A Localization Algorithm Using a Mobile Anchor Node Based on Region Determination in Underwater Wireless Sensor Networks

At present, most underwater positioning algorithms improve the positioning accuracy by increasing the number of anchor nodes which resulting in the increasing energy consumption. To solve this problem, the paper proposes a localization algorithm assisted by mobile anchor node and based on region determination(LMRD), which not only improves the positioning accuracy of nodes positioning but also reduces the energy consumption. This algorithm is divided into two stages: region determination stage and location positioning stage. In the region determination stage, the target region is divided into several sub-regions by the region division strategy with the smallest overlap rate which can reduce the number of virtual anchor nodes and lock the target node to a sub-region, and then through the planning of mobile nodes to optimize the travel path, reduce the moving distance, and reduce system energy consumption. In the location positioning stage, the target node location can be calculated using the HILBERT path planning and trilateration. The simulation results show that the proposed algorithm can improve the positioning accuracy when the energy consumption is reduced.

Clinical value of regional lymph node sorting in gastric cancer

BACKGROUND Increasing evidence have shown that regional lymph node metastasis is a critical prognostic factor in gastric cancer(GC).In addition,lymph node dissection is a key factor in determining the appropriate treatment for GC.However,the association between the number of positive lymph nodes and area of lymph node metastasis in GC remains unclear.AIM To investigate the clinical value of regional lymph node sorting after radical gastrectomy for GC.METHODS This study included 661 patients with GC who underwent radical gastrectomy at Tianjin Medical University General Hospital between January 2012 and June 2020.The patients were divided into regional sorting and non-sorting groups.Clinicopathological data were collected and retrospectively reviewed to determine the differences in the total number of lymph nodes and number of positive lymph nodes between the groups.Independent sample t-tests were used for intergroup comparisons.Continuous variables that did not conform to a normal distribution were expressed as median(interquartile range),and the Mann-Whitney U test was used for inter-group comparisons.RESULTS There were no significant differences between the groups in terms of the surgical method,tumor site,immersion depth,and degree of differentiation.The total number of lymph nodes was significantly higher in the regional sorting group(n=324)than in the non-sorting group(n=337)(32.5 vs 21.2,P<0.001).There was no significant difference in the number of positive lymph nodes between the two groups.A total of 212 patients with GC had lymph node metastasis in the lymph node regional sorting group,including 89(41.98%)cases in the first dissection station and 123(58.02%)cases in the second dissection station.Binary and multivariate logistic regression results showed that the number of positive lymph nodes(P<0.001)was an independent risk factor for lymph node metastases at the second dissection station.CONCLUSION Regional sorting of lymph nodes after radical gastrectomy may increase the number of detected lymph nodes,thereby improving the reliability and accuracy of lymph node staging in clinical practice.

Accuracy of Ultrasound Examination of Loco-Regional Lymph Nodes in Breast Cancer Follow-Up and Its Role in the Axillary Surgical Management

Objective: Major international guidelines have not standardized the sequence of diagnostic examinations during the follow-up of a patient with a diagnosed breast cancer. The aim of this study is to investigate the accuracy of sonography in the diagnosis of loco-regional lymphatic recurrences in comparison to the core needle biopsy results. Materials and Methods: Among 6455 patients who were followed up with clinical examination, mammography and ultrasound between January 2004 and November 2011, 125 (1.93%) patients had to be investigated with a core needle biopsy of a sonographically suspicious loco-regional lymph node. Results: Among the whole series, a total of 142 ultrasound-guided core needle biopsies were performed. Follow-up for the primary tumor lasted for a median time of 6.1 years (range 1 - 27 years). Ultrasound of suspicious loco-regional lymph nodes showed a sensitivity of 89.5%, a specificity of 87.1% and a positive predictive value of 89.5%. Conclusions: In our experience, ultrasound of suspicious loco-regional lymph nodes showed good accuracy and it should be a part of the standard examinations performed during follow-up for breast cancer.

Sentinel-Node-Driven Personalized Radiation Techniques Ranging from Partial Breast Irradiation to Regional Nodal Radiation after Breast-Conserving Surgery

Background: Breast-conserving surgery (BCS) followed by whole breast irradiation (WBI) has become the standard of care for treating patients with early-stage breast cancer. Recently, various radiation techniques followed by BCS have been reported. We have been investigating “personalized radiotherapy after BCS” ranging from accelerated partial breast irradiation (APBI) to WBI with regional nodal irradiation (RNI) based on the axillary node status. In this study, we compared different cohorts that received personalized radiotherapy. Method: Of 317 consecutive patients who underwent BCS followed by radiotherapy since November 2007, 187 who received APBI and 122 who received WBI were analyzed. Results: The local-only recurrence rate was 1.1% in the APBI group and 3.3% in the WBI group, and the regional-only recurrence rate was 1.1% for APBI and 0.8% for WBI. Conclusions: The clinical efficacy of APBI for local control after BCS was comparable to that of WBI ± RNI. Although this study was based on a small number of patients with a short follow-up period, the feasibility of breast-conserving therapy using multicatheter brachytherapy to achieve acceptable clinical outcomes was demonstrated.

基于Region多层结构P2P计算网络模型

分布式P2P网络Gnutella模型中共享信息查询的路由协议为“洪泛”算法,其协议机制仅在应用层实现,缺乏对Internet底层通信子网路由资源的利用,存在可扩展性、性能与效率不高的问题.以“小世界和幂规律”模型为理论基础,以层和域为基本逻辑管理单位,按用户需求和共享目的组织域,提出了基于Region多层结构P2P网络模型RLP2P(region-layerP2P),实现了其系统原型;实现了一个优化的MultilayerLight-Gossip分级路由策略;量化分析了表征模型数据通道质量指标的压力和伸展率,提出了综合考虑压力和伸展率的思想.模拟分析表明,RLP2P模型可以有效地解决可扩展性、性能与效率不高问题,且网络规模越大,其综合性能的优越性越明显,因此,模型是合理、有效的.

On the road to standardization of D2 lymph node dissection in a European population of patients with gastric cancer

The amount of lymph node dissection(LD) required during surgical treatment of gastric cancer surgery has been quite controversial.In the 1970 s and 1980 s,Japanese surgeons developed a doctrine of aggressive preventive gastric cancer surgery that was based on extended(D2) LD volumes.The West has relatively lower incidence rates of gastric cancer,and in Europe and the United States the most common LD volume was D0-1.This eventually caused a scientific conflict between the Eastern and Western schools of surgical thought.:Japanese surgeons determinedly used D2 LD in surgical practice,whereas European surgeons insisted on repetitive clinical trials in the European patient population.Today,however,one can observe the results of this complex evolution of views.The D2 LD is regarded as an unambiguous standard of gastric cancer surgical treatment in specialized European centers.Such a consensus of the Eastern and Western surgical schools became possible due to the longstanding scientific and practical search for methods that would help improve the results of gastric cancer surgeries using evidence-based medicine.Today,we can claim that D2 LD could improve the prognosis in European populations of patients with gastric cancer,but only when the surgical quality of LD execution is adequate.

考虑极限诱导分岔的静态电压稳定域

随着高比例可再生能源在电力系统中的广泛应用,可再生能源的波动性和随机性对电力系统静态电压稳定评估带来挑战,电力系统静态电压稳定域(static voltage stability region,SVSR)可以全面分析和监测电力系统电压稳定性,其关键是快速准确地构建稳定域边界。针对传统连续潮流法和非线性规划法计算量大的问题,提出一种基于SVSR边界拓扑性质的SVSR边界构建优化模型,根据边界连续且光滑的性质,由已知边界点通过预测-校正方法直接计算相邻边界点。在此模型基础上提出一种极限诱导分岔识别方法,构建考虑极限诱导分岔的SVSR边界。最后通过算例分析验证了所提方法的可行性和准确性。

基于RSS_GN RRT算法的狭长空间路径规划

针对RRT算法在狭长空间中存在的收敛速度慢及规划路径不平滑的问题,提出了一种RSS_GN RRT算法。为了提升算法的收敛速度,提出了引导节点导向策略与分区域采样策略,极大地减少了算法对无效区域的搜索;其次,算法引入了采样角度约束策略来提高规划路径的质量,并采用父节点拓展选择的方法有效解决了由角度约束引起的迭代次数增加的问题。此外,算法可根据感知信息进行地图地动态重构并规划避障路径,提高了算法在低速动态环境中的适应性。仿真结果显示,在狭长通道环境中,RSS_GN RRT算法在规划路径的耗时上比RRT、Goal_bias RRT、角度约束下的RRT、Informed RRT*及DR-RRT算法分别减少了77.3%,51.9%,84.7%,98.8%和60.3%。在迭代次数上,相比于上述算法,分别减少了95.9%,92%,98.3%,98.3%和89.5%。路径的平均曲率也分别降低了94.1%,93.2%,88.7%,91%和92.9%。仿真结果证明了RSS_GN RRT算法在提升规划速度和改善路径质量方面具有显著优势。同时,本文采用了阿克曼模型的小车实测了算法的局部避障能力。经测试,小车可对行驶途中出现的障碍物进行合理避让。

高分辨MR成像联合ADC值预测直肠癌新辅助放化疗后区域淋巴结转移的价值

目的 探讨高分辨MR成像联合表观扩散系数(ADC)值预测直肠癌新辅助放化疗(nCRT)后区域淋巴结转移的效能。方法纳入青岛大学附属青岛市中心医院2020年5月至2022年5月收治的93局部进展期直肠癌患者为研究对象,于nCRI前、结束时6~8周接受高分辨率MRI T2WI、弥散加权成像检查并在1周内行全直肠系膜切除术。根据术后病理结果分为淋巴结转移组(n=24)和未转移组(n=69)。比较两组nCRT前、后淋巴结短径、长径、ADC值及其变化百分比绝对值(Δ%),分析高分辨MR成像联合ADC值预测直肠癌nCRT后区域淋巴结转移的价值。结果 转移组nCRT前后淋巴结短径均大于非转移组,nCRT前ADC值均小于非转移组(P<0.05);转移组Δ短径%、ΔADC%值均小于非转移组(P<0.05);但两组nCRT前后长径及Δ长径%值比较,差异无统计学意义(P>0.05);经Logistic回归分析显示,Δ短径%、MDC%是直肠癌患者nCRT后区域淋巴结转移的独立预测指标;绘制受试者工作曲线(ROC)显示,Δ短径%、ΔADC%单独及联合预测直肠癌患者nCRT后区域淋巴结转移的曲线下面积(AUC)分别为0.748、0.852、0.879,具有一定预测价值。结论 高分辨MR成像联合ADC值预测直肠癌nCRT后区域淋巴结转移具有一定的价值,其中淋巴结短径与ADC值变化可有效提示nCRT后区域淋巴结转移情况。

探讨常规超声及剪切波弹性成像在甲状腺乳头状癌颈部淋巴结转移中的影响因素

目的:探讨常规超声中的不同指标及剪切波弹性成像(SWE)中的不同弹性模量值对甲状腺乳头状癌(PTC)患者颈部淋巴结转移的影响,并进一步探讨SWE中的不同弹性模量值的诊断效能,找出其最佳诊断界值。方法:选取2017年6月—2023年6月在青岛大学附属医院就诊的92例(122枚肿大淋巴结)患者,均经病理或FNA诊断为PTC,且均安排接受甲状腺切除手术并进行颈部淋巴结清扫,测量最大弹性值(Emax-2)、平均弹性值(Emean-2)、最小弹性值(Emin-2)和弹性标准差(SD-2),确定受试者工作特征(ROC)曲线下面积、95%置信区间,灵敏度、特异度及约登指数,并比较SWE中各弹性模量值的诊断性能。结果:122枚肿大淋巴结中,恶性淋巴结63枚(51.64%);良性淋巴结59枚(48.36%)。颈部良性组与恶性组的短径、纵横比、形态、有无钙化、有无淋巴门、血流分型、Emean-2、Emax-2、Emin-2、SD-2对比,差异有统计学意义(P<0.05);而性别、年龄、长径对比,差异无统计学意义(P>0.05)。ROC曲线分析结果显示,淋巴结中Emax-2、Emean-2、Emin-2、SD-2值的曲线下面积分别为0.868、0.861、0.824、0.776,以Emax-2的诊断效能最佳,以28.00 kPa为诊断界值时,分别对应的灵敏度为84.13%、特异度为83.64%、约登指数为0.678。结论:常规超声中淋巴结的短径、纵横比、形态、有无钙化、有无淋巴门和血流分型及SWE的4个弹性模量值均有助于对甲状腺乳头状癌颈部淋巴结是否转移进行鉴别诊断,其中Emax-2约登指数最佳,诊断效能最高。

无人机河湖巡检中BPT结点区域合并算法应用研究

针对无人机河湖巡检图像存在较高的域内异质性、域间同质性,使用单阶段的分割算法易形成不完整目标区域提取结果等问题,设计一种基于二叉划分树结点的区域合并算法。算法包含初始分割、区域合并2个阶段,采用分水岭算法进行初始分割形成误分割率较低的过分割区域集,对过分割区域集合中的区域对进行相似性度量,根据过相似性度量结果构建BPT树,遍历BPT树确定过分割区域集合的合并次序。在河湖巡检数据集上,与自适应区域合并进行对比,结果表明:基于二叉划分树结点的区域合并算法的分割精度、时间效率均优于自适应区域合并算法,可以实现目标在图像中的精确提取。

胃癌区域淋巴结体积测量:球面感兴趣区CT阈值法和手动勾画计算容积法的比较

目的:比较和分析两种基于CT影像的胃癌区域淋巴结体积测量方法--球面感兴趣区(Sphere ROI) CT阈值法和手动勾画计算容积法的一致性。方法:收集接受根治性手术治疗的81例胃癌患者资料,根据纳入和排除标准,从转移性、非转移性淋巴结中各选取50枚进行测量和分析,比较两种方法测量淋巴结体积的一致性。一致性检验采用Kappa检验和组内相关系数(ICC)检验。结果:2名医师应用手动勾画计算容积法测量淋巴结体积的一致性(Kappa=0.823,ICC=0.980),以及应用Sphere ROI CT阈值法测量淋巴结体积的一致性(Kappa=0.892,ICC=0.992)均良好,且后者优于前者。另一方面,医师A在不同时间点应用手动勾画计算容积法测量淋巴结体积的一致性(Kappa=0.822, ICC=0.988),以及应用Sphere ROI CT阈值法测量淋巴结体积的一致性(Kappa=0.874,ICC=0.994)也较好,且后者优于前者。结论:Sphere ROI CT阈值法在胃癌区域淋巴结体积测量的一致性优于手动勾画计算容积法,且操作更简单便捷,推荐在胃癌区域淋巴结体积测量上优先考虑使用Sphere ROI CT阈值法。

从“反磁力中心”到“区域节点城市”——论新时代大城市新城建设的功能迭代与规划策略

新时代的新城建设,在应对大城市(含超大、特大城市,下同)发展挑战中的作用与规划策略正在发生变化。本文基于田园城市、区域多中心主义、全球城市网络和“流空间”等理论概念,以“基础性”和“战略性”为视角,对国内外新城建设历程作回溯,并对发展趋势作阐释:一方面,新城作为疏解大城市中心城区人口和产业的“反磁力”中心的作用仍在延续;另一方面,新城的功能亦不断迭代,以至蜕变为“区域节点城市”。鉴于此,本文最后探讨新时代的新城认知更新和规划策略。由于大城市往往具有全球城市的链接特性,而先进生产服务业在空间上呈现集聚和分散两种趋势,可在不同等级中心布局;某些重点新城作为市域的副中心,则可成为全球/区域生产性服务业网络中的节点城市。因而,在新时代的规划中,要主动谋划和引导新城功能迭代,发挥新城作为大城市的功能疏解与区域节点城市的双重作用。

以银杏古树为节点的环渤海地区国家森林步道建设构想

银杏古树是中国历史文化的重要标识,以银杏古树作为节点建设森林步道可能具有重要的生态、经济和文化意义。文中以环渤海地区为研究对象,调查区域内银杏古树128处161株,评价其区域适宜性、旅游适宜性、建设适宜性,认为总体上银杏古树适宜作为环渤海森林步道的节点。从综合评价来看,适宜作为步道节点的银杏古树,共计100处117株,其中32株古树重点推荐作为途经节点。初步设计了以银杏古树为节点的环渤海地区森林步道选线方案,由6条线路构成,即大连—丹东—迁安线、北京北线、北京南线、易县—肥城线、肥城—淄博—海阳线、肥城—莒县—荣成线,途经银杏古树79处96株,总里程约为7352 km。在此基础上,根据环渤海森林步道以银杏古树为节点这一特色,提出优化建设机制、加强银杏古树原真性保护、加强步道生态保护、强化资金保障、推进步道使用、加强代表性景观的宣传等建议。

进展期食管胃结合部恶性肿瘤主动脉旁淋巴结转移患者的危险因素及预后分析

目的 通过对比进展期食管胃结合部恶性肿瘤患者一般临床病理特征及区域淋巴结转移状态,探讨患者主动脉旁淋巴结转移阳性的危险因素及其预后。方法 收集224例手术根治性切除食管胃结合部恶性肿瘤患者临床病理资料,对影响第16组淋巴结转移的危险因素进行单因素χ2检验和多因素Logistic回归分析。生存分析采用Kaplan-Meier法,生存率比较采用Log rank检验。结果(1)单因素分析见Siewert分型、肿瘤大小、病理分期、T分期、N分期与主动脉旁淋巴结转移阳性相关(均P<0.05)。多因素分析发现Siewert分型、肿瘤大小均是其转移阳性的独立危险因素(均P<0.001)。(2)纳入的17组区域淋巴结与主动脉旁淋巴结转移相关的单因素分析中,除No.5、No.6、No.111、No.112组淋巴结与主动脉旁淋巴结转移阳性不相关(均P>0.05),剩余13组区域淋巴结均与其相关。多因素分析发现,No.7、No.11p、No.110组淋巴结均是其转移阳性的独立危险因素(均P<0.05)。进一步分析发现,当至少其中一组区域淋巴结转移时,阳性转移率高达47.4%(3组均阴性时仅4.7%)。(3)主动脉旁淋巴结转移阳性患者术后1年、3年累积生存率分别为76.5%、8.1%,阴性患者分别为98.3%、76.8%。Log rank检验表明两组总生存率存在明显差异(P<0.001)。结论(1)进展期食管胃结合部恶性肿瘤患者术前检查应明确患者的肿瘤分型及大小,建议SiewertⅡ、Ⅲ型和肿瘤直径>6 cm的患者行主动脉旁淋巴结清扫术。(2)术中行No.7、No.11p、No.110淋巴结冰冻活检病理,发现转移阳性后行主动脉旁淋巴结清扫术,有助于术中对清扫主动脉旁淋巴结的判断。

双源CT能谱成像多参数在宫颈癌区域淋巴结定性诊断中的价值研究

目的 分析双源CT能谱成像多参数对宫颈癌区域淋巴结的定性诊断价值。方法 选择2021年5月至2022年5月新疆维吾尔自治区人民医院收治的102例经病理活检诊断为宫颈癌且存在区域淋巴结肿大患者,年龄27~68岁,平均年龄51.23岁;身体质量指数21~29 kg/m^(2),平均身体质量指数22.86 kg/m^(2);根据国际妇产科联盟(FIGO)分期标准,Ⅰ期15例,Ⅱ期39例,Ⅲ期42例,Ⅳ期6例;组织病理学类型,鳞癌86例,腺癌12例,腺鳞癌3例,透明细胞癌1例。所有患者均进行双源CT能谱成像检查,行动脉期及静脉期增强扫描,检测标准化碘浓度(NIC)和能谱曲线斜率(λHU);根据术后淋巴结的病理结果,分为淋巴结转移组和淋巴结未转移组,比较两组动脉期及静脉期的NIC、λHU,使用受试者工作特性(ROC)曲线分析其诊断效能。结果 在102例经病理活检诊断为宫颈癌且存在区域淋巴结肿大患者中,CT检出淋巴结共531个。根据术后淋巴结的病理诊断,分为淋巴结转移组345个和淋巴结未转移组186个。淋巴结转移组动脉期及静脉期的NIC、λHU均大于淋巴结未转移组,差异均有统计学意义(动脉期:0.41±0.19 vs 0.20±0.12,6.78±1.43 vs 2.41±0.55。静脉期:0.68±0.56 vs 0.39±0.27,5.85±1.37 vs 3.72±0.61。P <0.05);经ROC曲线分析,动脉期NIC、λHU及静脉期NIC、λHU定性诊断宫颈癌区域淋巴结的ROC曲线下面积(AUC)分别为0.925、0.905和0.935、0.930,最佳截断值分别为0.44、7.53和0.76、5.95,灵敏度分别为76.65%、68.91%和72.53%、75.76%,特异度分别为81.92%、93.47%和74.58%、82.43%。结论 运用双源CT能谱成像多参数进行定量分析,在宫颈癌区域淋巴结定性诊断中具有较大意义,可作为术前判断区域淋巴结转移的重要依据之一。

基于改进双树RRT^(*)算法的冗余机械臂末端路径规划

针对冗余机械臂的冗余特性与相关RRT^(*)算法在规划机械臂末端路径的应用中存在的搜索效率较低、收敛性不稳定以及没有充分考虑到机械臂末端几何构型与自身运动特性对路径规划影响的问题,提出一种改进策略。首先,引入一种基于根尾节点连线夹角的采样点选择方式,并设置目标逼近区域。根据连续采样成功次数动态选择改进采样与随机采样。接着,将双树扩展策略与上述方法相结合。最后,将初始可行路径进行二次重连得到最终的优化路径。通过验证,改进双树RRT^(*)方法能够有效地提升搜索效率、收敛性以及路径的优越性。虚拟碰撞体与胶囊碰撞体的引入也能较好地应对机械臂末端结构与运动特性带来的影响。使用Mujoco物理仿真引擎进行机械臂运动验证,证明该策略可以为冗余机械臂末端规划出一条较优的可行路径。

基于冗余筛选管控评估机制的移动传感网超宽带稳定传输算法

为了优化WSN网络的数据传输特性,设计了基于冗余筛选管控评估的移动WSN超宽带稳定传输算法。基于冗余传输调度机制对区域予以初次分割,通过能量评估方式快速达到区域聚类稳定生存效果,结合构建区域节点能量阈值的方法提高聚类冗余效率,以降低超宽带条件下的节点受限概率。采用区域边界控制方式,通过优化骨干节点剩余能量的方式增强骨干节点工作效率,降低因骨干节点而导致的区域传输抖动,确保中继传输节点性能最佳,以降低链路抖动现象。通过骨干节点能力对传输节点予以甄选,从而提升网络链路传输能力,进一步降低抖动现象对传输性能带来的不利影响。仿真实验表明,所提算法具有更低的网络链路累计抖动频次及更好的网络传输带宽。

Different types of tumor microvessels in stageⅠ-ⅢA squamous cell lung cancer and their clinical significance

BACKGROUND Lung cancer(LC)is the leading cause of morbidity and mortality among malignant neoplasms.Improving the diagnosis and treatment of LC remains an urgent task of modern oncology.Previously,we established that in gastric,breast and cervical cancer,tumor microvessels(MVs)differ in morphology and have different prognostic significance.The connection between different types of tumor MVs and the progression of LC is not well understood.AIM To evaluate the morphological features and clinical significance of tumor MVs in lung squamous cell carcinoma(LUSC).METHODS A single-center retrospective cohort study examined medical records and archival paraffin blocks of 62 and 180 patients with stage I-IIIA LUSC in the training and main cohorts,respectively.All patients underwent radical surgery(R0)at the Orenburg Regional Cancer Clinic from May/20/2009 to December/14/2021.Tumor sections were routinely processed,and routine Mayer's hematoxylin and eosin staining and immunohistochemical staining for cluster of differentiation 34(CD34),podoplanin,Snail and hypoxia-inducible factor-1 alpha were performed.The morphological features of different types of tumor MVs,tumor parenchyma and stroma were studied according to clinicopathological characteristics and LUSC prognosis.Statistical analysis was performed using Statistica 10.0 software.Univariate and multivariate logistic regression analyses were performed to identify potential risk factors for LUSC metastasis to regional lymph nodes(RLNs)and disease recurrence.Receiver operating characteristic curves were constructed to discriminate between patients with and without metastases in RLNs and those with and without disease recurrence.The effectiveness of the predictive models was assessed by the area under the curve.Survival was analyzed using the Kaplan-Meier method.The log-rank test was used to compare survival curves between patient subgroups.A value of P<0.05 was considered to indicate statistical significance.RESULTS Depending on the morphology,we classified tumor vessels into the following types:normal MVs,dilated capillaries(DCs),atypical DCs,DCs with weak expression of CD34,"contact-type"DCs,structures with partial endothelial linings,capillaries in the tumor solid component and lymphatic vessels in lymphoid and polymorphocellular infiltrates.We also evaluated the presence of loose,fine fibrous connective tissue(LFFCT)and retraction clefts in the tumor stroma,tumor spread into the alveolar air spaces(AASs)and fragmentation of the tumor solid component.According to multivariate analysis,the independent predictors of LUSC metastasis in RLNs were central tumor location(P<0.00001),the presence of retraction clefts(P=0.003),capillaries in the tumor solid component(P=0.023)and fragmentation in the tumor solid component(P=0.009),whereas the independent predictors of LUSC recurrence were tumor grade 3(G3)(P=0.001),stage N2(P=0.016),the presence of LFFCT in the tumor stroma(P<0.00001),fragmentation of the tumor solid component(P=0.0001),and the absence of tumor spread through the AASs(P=0.0083).CONCLUSION The results obtained confirm the correctness of our previously proposed classification of different types of tumor vessels and may contribute to improving the diagnosis and treatment of LUSC.

能耗均衡与节能的自适应水下路由协议

针对水下传感器网络中节点能耗不均衡和能量有限的问题,提出一种能耗均衡与节能的自适应水下路由协议ECBES(energy consumption balanced and energy saving adaptive underwater routing protocol)。构建双区非均匀分层拓扑。基于能耗均衡因子,利用拓扑和节点剩余能量计算节点转发优先级,实现自适应转发节点选择,均衡网络能耗。与此同时,通过候选转发区域各分区域中节点参与转发数据包的比例确定次优候选转发区域,将次优候选转发区域作为初始策略,利用策略迭代思想确定最优候选转发区域,保证投递率的同时减少不同网络规模中重复数据包的转发,降低网络的整体能耗。仿真结果表明,ECBES相比VBF、ES-VBF和ALRP,在不同节点数量下,节点死亡率均最低,在保证数据包投递率的同时,能耗最少。