基于WEP-QTP模型的近65 a黄河源区径流演变分析

为研究黄河源区径流演变规律,以WEP-QTP(The Water and Energy transfer Processes in the Qinghai⁃Tibet Plateau)模型为基础构建基于水热耦合的黄河源区冻土水文模型。采用玛曲站2019—2021年冻融期逐日土壤温度及土壤液态含水率对模型进行验证,率定期及验证期决定系数(R2)均值为0.8左右,均方根误差(RMSE)均值分别为1.0℃及0.04左右;采用8个冻土监测点1971—2000年冻融期逐日冻土深度进行验证,决定系数(R2)均值为0.89,均方根误差(RMSE)均值为214.81 mm。模型模拟黄河源区1956—2020年逐月流量过程,效率系数(NSE)为0.8左右,相对误差(RE)为5%左右,表明模型能较好地模拟黄河源区径流过程。利用M-K趋势检验分析得到1956—2020年黄河源区径流呈不显著增加趋势,其变化趋势是降水与气温共同影响的结果。冻融期、非冻融期径流与全年趋势一致。降水增加、气候变暖及冻土退化使径流组分发生变化,地表径流及地下径流均呈增加趋势,但地下径流在全年及冻融期增加趋势更加显著。

Noether's theorem for non-conservative Hamilton system based on El-Nabulsi dynamical model extended by periodic laws

This paper focuses on the Noether symmetries and the conserved quantities for both holonomic and nonholonomic systems based on a new non-conservative dynamical model introduced by E1-Nabulsi. First, the E1-Nabulsi dynamical model which is based on a fractional integral extended by periodic laws is introduced, and E1-Nabulsi-Hamilton＇s canoni- cal equations for non-conservative Hamilton system with holonomic or nonholonomic constraints are established. Second, the definitions and criteria of E1-Nabulsi-Noether symmetrical transformations and quasi-symmetrical transformations are presented in terms of the invariance of E1-Nabulsi-Hamilton action under the infinitesimal transformations of the group. Fi- nally, Noether＇s theorems for the non-conservative Hamilton system under the E1-Nabulsi dynamical system are established, which reveal the relationship between the Noether symmetry and the conserved quantity of the system.

Periodic Modulation of Nonlinearity in a Two-Core Photonic Crystal Fiber: A Numerical Investigation

We present a numerical investigation of the propagation and the switching of ultra-short pulses (100 fs) in a two-core nonlinear coupler of photonic crystal fibers constructed with periodically modulated the non-linearity fiber (PMNL-PFC). Our simulations are taking into account different amplitude and frequency modulations of the PMNL-PFC. A coupler for coupling whose length is Lc = 1.8 cm, the transmission characteristics, the compression factor, the crosstalk (Xtalk) and extinction ratio (Xratio) levels of the first order solitons were studied for low to high pump energies considering 2Lc. By an analysis on the reference channel (channel 2), it is observed that at low modulation frequencies an increase occurs in the switching power increasing transmission efficiency. For high modulation frequencies, the transmitted energy efficiency loses. The switching pulses are stronger for low frequency and high amplitude modulation. The Xtalk is a function of the measurement made on the secondary channel (channel 1). It was observed that this unwanted high-frequency energy increases to lessen the measure of the amplitude modulation. In summary, we have demonstrated that introduction of a non-linearity profile takes the periodically modulated PMNL-PFC to strong variations at transmission efficiency, Xtalk, Xratio a function of frequency and modulation amplitude and the input power.

非小细胞肺癌组织中lncRNA FOXD2-AS1、miR-1913表达与患者生存期的关系

目的探究非小细胞肺癌(NSCLC)组织中长链非编码RNA(lncRNA)FOXD2-AS1、miR-1913的表达与患者生存期的关系。方法选取2017年11月—2019年11月滨州医学院烟台附属医院肿瘤中心收治的NSCLC患者100例癌组织和癌旁组织作为研究对象。根据术后3年预后情况分为生存组58例和死亡组42例,采用实时荧光定量—聚合酶链式反应(qRT-PCR)测定组织中lncRNA FOXD2-AS1、miR-1913表达水平;Pearson法分析NSCLC组织中lncRNA FOXD2-AS1与miR-1913表达水平的相关性;用Kaplan-Meier法分析NSCLC组织中lncRNA FOXD2-AS1、miR-1913表达与预后的关系;Cox分析NSCLC患者预后的影响因素。结果与癌旁组织比较,NSCLC组织中lncRNA FOXD2-AS1表达水平升高,miR-1913表达水平降低(t/P=11.439/<0.001、17.709/<0.001);Target Scan Human网址预测lncRNA FOXD2-AS1与miR-1913间存在结合位点;NSCLC组织中lncRNA FOXD2-AS1与miR-1913表达水平呈负相关(r=-0.406,P<0.001);与生存组比较,死亡组患者癌组织中lncRNA FOXD2-AS1表达水平升高,miR-1913表达水平降低(t/P=6.973/<0.001、6.307/<0.001);TNM分期为Ⅲ+Ⅳ期、发生淋巴结转移、低分化程度的NSCLC患者癌组织lncRNA FOXD2-AS1高表达比例高于TNM分期为Ⅰ+Ⅱ期、未发生淋巴结转移、中/高分化程度的NSCLC患者(χ^(2)/P=5.962/0.015、5.104/0.024、6.150/0.013),而miR-1913低表达比例高于TNM分期为Ⅰ+Ⅱ期、未发生淋巴结转移、中/高分化程度的NSCLC患者(χ^(2)/P=11.457/0.001、7.695/0.006、11.349/0.001);lncRNA FOXD2-AS1高表达NSCLC患者3年生存率低于lncRNA FOXD2-AS1低表达患者,miR-1913高表达患者3年生存率高于miR-1913低表达NSCLC患者(χ^(2)/P=7.830/0.005、6.125/0.013);多因素Cox分析显示,miR-1913高是NSCLC患者预后的保护因素[OR(95%CI)=0.864(0.774~0.964)],lncRNA FOXD2-AS1高、TNMⅢ+Ⅳ期、有淋巴结转移、分化程度低是NSCLC患者预后的危险因素[OR(95%CI)=2.544(1.481~4.370)、3.647(1.614~8.242)、2.544(1.481~4.370)、2.986(1.361~6.553)]。结论NSCLC组织中lncRNA FOXD2-AS1表达水平升高,miR-1913的表达水平降低,两者与患者预后生存期有关。

Einstein-Podolsky-Rosen entanglement in time-dependent periodic pumping non-degenerate optical parametric amplifier

The solution of the time-dependent periodic pumping non-degenerate optical parametric amplifier （NOPA） is derived when the pump depletion is considered both above and below thresholds. Based on this solution, the quantum fluctuation calculated shows that a high entanglement and a good squeezing degree of the parametric light beams are achieved near and above thresholds. We adopt two kinds of pump fields： （i） a continuously modulated pump with a sinusoidal envelope; （ii） a sequence of laser pulses with Gaussian envelopes. We analyse the time evolution of continuous variable entanglement by analytical and numerical calculations, and show that the periodic driven pumping also improves the degree of entanglement. The squeezing and Einstein-Podolsky-Rosen （EPR） entanglement by using the two pumping driven functions are investigated from below to above the threshold regions, the tendencies are nearly the same, and the Caussian driven function is superior to that of the sine driven function, when the maximum squeezing and the minimum variance of quantum fluctuation are considered. In the meantime, the generalization of frequency degenerate OPA to frequency non-degenerated OPA problem is investigated.

ON THE BOUNDEDNESS AND PERIODICITY OF THESOLUTIONS OF A CERTAIN VECTOR DIFFERENTIALEQUATION OF THIRD-ORDER

There are given sufficient conditions for the ultimate boundedness of solutions and for the existence of periodic solutions of a certain vector differential equation of third-order.

Wave Period Distributions in Non-Gaussian Mixed Sea States

The wave period probability densities in non-Gaussian mixed sea states are calculated by utilizing a transformed Gaussian process method. The transformation relating the non-Gaussian process and the original Gaussian process is obtained based on the equivalence of the level up-crossing rates of the two processes. A saddle point approximation procedure is applied for calculating the level up-crossing rates in this study. The accuracy and efficiency of the transformed Gaussian process method are validated by comparing the results predicted by using the method with those predicted by the Monte Carlo simulation method.

Aperture Field Estimation in Waveguide for Non-Sinusoidal Periodic Excitation

In this paper an attempt has been made to find the aperture field distribution in a rectangular waveguide for non-sinusoidal, periodic excitations using Multiple Cavity Modeling Technique. The excitation functions, considered, are square, trapezoidal and clipped sine wave in nature. In the present analysis these time domain excitation functions have been represented in terms of a truncated Fourier series consisting of the fundamental frequency and its higher harmonics. Within the waveguide the fundamental frequency will give rise to a dominant mode excitation whereas the higher order modes will excite dominant as higher order modes. If the higher harmonics are assumed suppressed then the waveguide is subjected only to a dominant mode excitation. Results for dominant mode reflection coefficient (magnitude), VSWR and complex transmission coefficient have been computed and compared with theoretical data. The excellent agreement between them validates the analysis.

Doubly Periodic Riemann Boundary Value Problem of Non-Normal Type for Analytic Functions on Two Parallel Curves

In this paper, we present and study a kind of Riemann boundary value problem of non-normal type for analytic functions on two parallel curves. Making use of the method of complex functions, we give the method for solving this kind of doubly periodic Riemann boundary value problem of non-normal type and obtain the explicit expressions of solutions and the solvable conditions for it.

TIME PERIODIC SOLUTIONS OF NON-ISENTROPIC COMPRESSIBLE MAGNETOHYDRODYNAMIC SYSTEM

In this paper, we study the non-isentropic compressible magnetohydrodynamic system with a time periodic external force in R^n. Under the condition that the optimal time decay rates are obtained by spectral analysis, we show that the existence, uniqueness and time-asymptotic stability of time periodic solutions when the space dimension n 〉 5. Our proof is based on a combination of the energy method and the contraction mapping theorem.

Periodic Solution for Stochastic Predator-Prey Systems with Nonlinear Harvesting and Impulses

In this paper, astochastic predator-prey systems with nonlinear harvesting and impulsive effect are investigated. Firstly, we show the existence and uniqueness of the global positive solution of the system. Secondly, by constructing appropriate Lyapunov function and using comparison theorem with an impulsive differential equation, we study that a positive periodic solution exists. Thirdly, we prove that system is globally attractive. Finally, numerical simulations are presented to show the feasibility of the obtained results.

Variations of Frost-free Period and Its Impact on Grain Yields in Henan Province during 1961-2013

The aim of this study was to investigate the responses of frost dates to global warming and its influences on grain yields. In this study, based on the frost date series defined by daily minimum ground temperature, the spatial and temporal characteristics of first frost date （FFD）, last frost date （LFD） and frost-free period （FFP） were analyzed. The impact of extending FFP on major crop yields was also studied. The results were as follows： FFD showed a significantly delaying trend of 2.2 d/10 y, and LFD presented an advancing trend of 2.4 d/10 y. FFP extended at a rate of 4.5 d/10 y due to the later FFD and earlier LFD. The most obvious trend of FFD was in westem Henan, while the most significant trend of LFD and FFP oc- curred in south central parts of the study area. However, in eestem region, the trends of FFD, LFD and FFP were not so obvious. Major crop yield showed a sig- nificant correlation with frost-free period for Henan during 1961-2013. The yields of grain, rice, wheat, and maize increased by 79.5, 90.0, 79.5 and 70.5 kg/hm2 with FFP extending by one day.

具有双密度制约和Non-Monotonic型功能反应的捕食扩散系统的周期解的存在性

利用重合度理论中的延拓定理,研究了一类具有双密度制约和Non-Monoton ic型功能反应的捕食者-食饵扩散系统正周期解的存在性问题。运用分析技巧获得了一个有界开集和至少存在一个周期正解的充分条件。揭示了当食饵群负载容纳量和捕食者种群增长率均足够大时,系统将产生生物性周期振荡现象。

肥胖儿童non-HDL-C、remnant cholesterol与亚临床动脉粥样硬化的关系

目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体质量儿童30例为III组(对照组)。比较3组儿童血脂指标,对肥胖组各项血脂指标与血浆致动脉粥样硬化指数(AIP)进行相关性分析,肥胖患儿体质指数、血脂指标与颈动脉内径、内膜-中层厚度(c-IMT)、血流参数进行相关性分析。结果:I组、II组的TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、non-HDL-C、remnant cholesterol、AIP均较对照组升高,高密度脂蛋白胆固醇(HDL-C)较对照组降低,且I组的remnant cholesterol、AIP均较II组升高。肥胖组儿童AIP与TG、non-HDL-C、remnant cholesterol呈正相关,与HDL-C呈负相关。37例行颈动脉超声检查的肥胖儿童的c-IMT较正常儿童的增厚。结论:non-HDL-C、remnant cholesterol在肥胖儿童亚临床AS中有重要作用,在肥胖儿童血脂异常的治疗中应关注non-HDL-C、remnant cholesterol的变化。

Periodic oscillation and fine structure of wedge-induced oblique detonation waves

An oblique detonation wave for a Mach 7 inlet flow over a long enough wedge of 30 turning angle is simulated numerically using Euler equation and one-step rection model.The fifth-order WENO scheme is adopted to capture the shock wave.The numerical results show that with the compression of the wedge wall the detonation wave front structure is divided into three sections：the ZND model-like strcuture,single-sided triple point structure and dual-headed triple point strucuture.The first structure is the smooth straight,and the second has the characteristic of the triple points propagating dowanstream only with the same velocity,while the dual-headed triple point structure is very complicated.The detonation waves facing upstream and downstream propagate with different velocities,in which the periodic collisions of the triple points cause the oscillation of the detonation wave front.This oscillation process has temporal and spatial periodicity.In addition,the triple point trace are recorded to obtain different cell structures in three sections.

我国非农劳动者超时工作的变化趋势研究——基于CSS2006-2021的分析

近年来,超时工作备受社会热议。根据传统劳动供给及相关理论,在社会变迁、经济转型背景下,本文利用CSS2006-2021数据和交叉分类(分层)随机效应的年龄-时期-队列模型(HAPC-CCREM),将非农劳动者超时工作的变化趋势纳入由宏观社会进程和微观生命历程构成的时间框架中进行研究。分析结果显示,2006-2011年间,我国非农劳动者超时工作的比例明显下降,2011-2021年间该比例波动较为平稳;并且,这种变化主要是反映社会经济发展的时期效应,而反映劳动力代际更替的队列效应并不明显。传统劳动供给及相关理论所涉的市场工资、人力资本、户口及就业身份、社会保障等因素对我国非农劳动者超时工作的可能性仍存在显著影响,并具有显著的时期效应,但队列效应并不显著。总之,2006年以来,宏观社会经济的时代发展是驱动我国非农劳动者超时工作的主要力量。

Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced non-small cell lung cancer： a meta-analysis

Objective： To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin（GP） in the treatment of advanced non-small cell lung cancer （NSCLC）. Methods： we performed a systematicsearch in the electronic databases such as Cochrane Library, Pubmed, Embase, Chinese Journal Full-text Database,Chinese Biomedical Literature Database, Chinese Science and Technology Periodical Full-text Database andWanfang Database up to 30 January 2017. Randomized controlled trials （RCT） of Shenqi Fuzheng Injectioncombined with GP chemotherapy in the treatment of advanced NSCLC were searched, and all the RCTs wereconducted on methodological quality assessment. Data extraction and data analysis were according to standards ofCochrane systematic review. Results： Eight trials were included including a total of 701 patients. Meta-analysisresults： Shenqi Fuzheng injection combined with GP chemotherapy could significantly improve the functionalstatus of patients with NSCLC （OR = 3.44, 95% CI [2.26, 5.25], P 〈 0.0001） and clinical treatment efficacy （OR =（OR = 0.31, 95%CI [0.20, 0.47], P 〈 0.0001. The rate of leukopenia （OR = .31, 95%CI [0.20,0.47], P 〈 0.0001）,thrombocytopenia （OR = 0.58, 95%CI [0.37, 0.91], P = 0.020）, hemoglobin decline （（OR = 0.31, 95%CI [0.16,0.59], P = 0.0004） and incidence of gastrointestinal reactions （OR = 0.58,P 〈 0.05） could be reduced. Conclusion：Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced NSCLC obtainedsignificantly clinical efficacy. The quality of the literature incorporated is low, the conclusion requires high-qualityresearch to further prove.

具双密度制约和Non-Monotonic型功能反应的捕食系统的周期性与全局稳定性

利用比较原理和重合度理论与Lyapunov函数,研究了一类具有双密度制约和Non-Monotonic型功能性反应食饵-捕食者系统的持久性和全局周期解的存在性及其全局稳定性,得到了周期系统存在唯一全局渐近稳定的正周期解的充分条件.所得结论推广了已有的结果.

Periodic Packing Mode for Trickle-Bed Reactors: Experiments and Modeling

A periodic packing mode of trickle-bed reactor (TBR) for the gas limited reaction was proposed. Hy-drogenation of 2-ethylanthraquinone over Pd/Al2O3 in a laboratory-scale TBR was taken as a test reaction for determining whether the periodic packing mode is advantageous. The effects of operating conditions and packing type on TBR performance were experimentally examined to demonstrate the cause-effect relationships. A mathe-matic model of TBR considering axial dispersion and fractional wetting was developed to quantitatively illuminate the reason of performance enhancement.

On the Existence of Time-periodic Solution to the Compressible Heat-conducting Navier-Stokes Equations

We study in this article the compressible heat-conducting Navier-Stokes equations in periodic domain driven by a time-periodic external force. The existence of the strong time-periodic solution is established by a new approach. First, we reformulate the system and consider some decay estimates of the linearized system.Under some smallness and symmetry assumptions on the external force, the existence of the time-periodic solution of the linearized system is then identi?ed as the ?xed point of a Poincare′ map which is obtained by the Tychonoff ?xed point theorem.Although the Tychonoff ?xed point theorem cannot directly ensure the uniqueness,but we could construct a set-valued function, the ?xed point of which is the timeperiodic solution of the original system. At last, the existence of the ?xed point is obtained by the Kakutani ?xed point theorem. In addition, the uniqueness of timeperiodic solution is also studied.