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Cyclic shear behavior of en-echelon joints under constant normal stiffness conditions 被引量:1
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作者 Bin Wang Yujing Jiang +3 位作者 Qiangyong Zhang Hongbin Chen Richeng Liu Yuanchao Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第9期3419-3436,共18页
To reveal the mechanism of shear failure of en-echelon joints under cyclic loading,such as during earthquakes,we conducted a series of cyclic shear tests of en-echelon joints under constant normal stiffness(CNS)condit... To reveal the mechanism of shear failure of en-echelon joints under cyclic loading,such as during earthquakes,we conducted a series of cyclic shear tests of en-echelon joints under constant normal stiffness(CNS)conditions.We analyzed the evolution of shear stress,normal stress,stress path,dilatancy characteristics,and friction coefficient and revealed the failure mechanisms of en-echelon joints at different angles.The results show that the cyclic shear behavior of the en-echelon joints is closely related to the joint angle,with the shear strength at a positive angle exceeding that at a negative angle during shear cycles.As the number of cycles increases,the shear strength decreases rapidly,and the difference between the varying angles gradually decreases.Dilation occurs in the early shear cycles(1 and 2),while contraction is the main feature in later cycles(310).The friction coefficient decreases with the number of cycles and exhibits a more significant sensitivity to joint angles than shear cycles.The joint angle determines the asperities on the rupture surfaces and the block size,and thus determines the subsequent shear failure mode(block crushing and asperity degradation).At positive angles,block size is more greater and asperities on the rupture surface are smaller than at nonpositive angles.Therefore,the cyclic shear behavior is controlled by block crushing at positive angles and asperity degradation at negative angles. 展开更多
关键词 En-echelon joint Cyclic shear tests Shear stress normal displacement Constant normal stiffness(CNS)
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Reversible solid-liquid conversion enabled by self-capture effect for stable non-flow zinc-bromine batteries 被引量:1
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作者 Xixi Zhang Xiaoke Wang +7 位作者 Guangmeng Qu Tairan Wang Xiliang Zhao Jun Fan Cuiping Han Xijin Xu Chunyi Zhi Hongfei Li 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第6期1035-1044,共10页
Non-flow aqueous zinc-bromine batteries without auxiliary components(e.g.,pumps,pipes,storage tanks)and ion-selective membranes represent a cost-effective and promising technology for large-scale energy storage.Unfort... Non-flow aqueous zinc-bromine batteries without auxiliary components(e.g.,pumps,pipes,storage tanks)and ion-selective membranes represent a cost-effective and promising technology for large-scale energy storage.Unfortunately,they generally suffer from serious diffusion and shuttle of polybromide(Br^(-),Br^(3-))due to the weak physical adsorption between soluble polybromide and host carbon materials,which results in low energy efficiency and poor cycling stability.Here,we develop a novel self-capture organic bromine material(1,10-bis[3-(trimethylammonio)propyl]-4,4'-bipyridinium bromine,NVBr4)to successfully realize reversible solid complexation of bromide components for stable non-flow zinc-bromine battery applications.The quaternary ammonium groups(NV^(4+)ions)can effectively capture the soluble polybromide species based on strong chemical interaction and realize reversible solid complexation confined within the porous electrodes,which transforms the conventional“liquid-liquid”conversion of soluble bromide components into“liquid-solid”model and effectively suppresses the shuttle effect.Thereby,the developed non-flow zinc-bromide battery provides an outstanding voltage platform at 1.7 V with a notable specific capacity of 325 mAh g^(-1)NVBr4(1 A g^(-1)),excellent rate capability(200 mAh g^(-1)NVBr4 at 20 A g^(-1)),outstanding energy density of 469.6 Wh kg^(-1)and super-stable cycle life(20,000 cycles with 100%Coulombic efficiency),which outperforms most of reported zinc-halogen batteries.Further mechanism analysis and DFT calculations demonstrate that the chemical interaction of quaternary ammonium groups and bromide species is the main reason for suppressing the shuttle effect.The developed strategy can be extended to other halogen batteries to obtain stable charge storage. 展开更多
关键词 Solid-liquid conversion Self-capture non-flow zinc-bromine batteries Quaternary ammonium
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Extraction of Acoustic Normal Mode Depth Functions Using Range-Difference Method with Vertical Linear Array Data
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作者 GAO Siyu LI Weilu +2 位作者 ZHANG Yinquan LI Xiaolei WANG Ning 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第4期871-882,共12页
Data-derived normal mode extraction is an effective method for extracting normal mode depth functions in the absence of marine environmental data.However,when the corresponding singular vectors become nonunique when t... Data-derived normal mode extraction is an effective method for extracting normal mode depth functions in the absence of marine environmental data.However,when the corresponding singular vectors become nonunique when two or more singular values obtained from the cross-spectral density matrix diagonalization are nearly equal,this results in unsatisfactory extraction outcomes for the normal mode depth functions.To address this issue,we introduced in this paper a range-difference singular value decomposition method for the extraction of normal mode depth functions.We performed the mode extraction by conducting singular value decomposition on the individual frequency components of the signal's cross-spectral density matrix.This was achieved by using pressure and its range-difference matrices constructed from vertical line array data.The proposed method was validated using simulated data.In addition,modes were successfully extracted from ambient noise. 展开更多
关键词 range difference depth function extraction normal mode
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NORMALIZED SOLUTIONS FOR THE GENERAL KIRCHHOFF TYPE EQUATIONS
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作者 Wenmin LIU Xuexiu ZHONG Jinfang ZHOU 《Acta Mathematica Scientia》 SCIE CSCD 2024年第5期1886-1902,共17页
In the present paper,we prove the existence,non-existence and multiplicity of positive normalized solutions(λ_(c),u_(c))∈R×H^(1)(R^(N))to the general Kirchhoff problem-M■,satisfying the normalization constrain... In the present paper,we prove the existence,non-existence and multiplicity of positive normalized solutions(λ_(c),u_(c))∈R×H^(1)(R^(N))to the general Kirchhoff problem-M■,satisfying the normalization constraint f_(R)^N u^2dx=c,where M∈C([0,∞))is a given function satisfying some suitable assumptions.Our argument is not by the classical variational method,but by a global branch approach developed by Jeanjean et al.[J Math Pures Appl,2024,183:44–75]and a direct correspondence,so we can handle in a unified way the nonlinearities g(s),which are either mass subcritical,mass critical or mass supercritical. 展开更多
关键词 normalized solution Kirchhoff type equations general nonlinearities asymptotic behavior
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Schur Forms and Normal-Nilpotent Decompositions
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作者 LI Zhen 《应用数学和力学》 CSCD 北大核心 2024年第9期1200-1211,共12页
Real and complex Schur forms have been receiving increasing attention from the fluid mechanics community recently,especially related to vortices and turbulence.Several decompositions of the velocity gradient tensor,su... Real and complex Schur forms have been receiving increasing attention from the fluid mechanics community recently,especially related to vortices and turbulence.Several decompositions of the velocity gradient tensor,such as the triple decomposition of motion(TDM)and normal-nilpotent decomposition(NND),have been proposed to analyze the local motions of fluid elements.However,due to the existence of different types and non-uniqueness of Schur forms,as well as various possible definitions of NNDs,confusion has spread widely and is harming the research.This work aims to clean up this confusion.To this end,the complex and real Schur forms are derived constructively from the very basics,with special consideration for their non-uniqueness.Conditions of uniqueness are proposed.After a general discussion of normality and nilpotency,a complex NND and several real NNDs as well as normal-nonnormal decompositions are constructed,with a brief comparison of complex and real decompositions.Based on that,several confusing points are clarified,such as the distinction between NND and TDM,and the intrinsic gap between complex and real NNDs.Besides,the author proposes to extend the real block Schur form and its corresponding NNDs for the complex eigenvalue case to the real eigenvalue case.But their justification is left to further investigations. 展开更多
关键词 Schur form normal matrix nilpotent matrix tensor decomposition vortex identification
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NORMALITY AND THE NUMBER OF ZEROS
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作者 WANG Guang-sheng WEI Dong-mei XU Yan 《数学杂志》 2024年第5期377-382,共6页
In this paper,we study normal families of meromorphic functions.By using the idea in[11],we obtain some normality criteria for families of meromorphic functions that concern the number of zeros of the differential pol... In this paper,we study normal families of meromorphic functions.By using the idea in[11],we obtain some normality criteria for families of meromorphic functions that concern the number of zeros of the differential polynomial,which extends the related result of Li,and Chen et al..An example is given to show that the hypothesis on the zeros of a(z)is necessary. 展开更多
关键词 Meromorphic function normal family differential polynomial ZERO
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Shear mechanical properties and frictional sliding responses of rough joint surfaces under dynamic normal displacement conditions
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作者 ZHU Qiang YIN Qian +9 位作者 TAO Zhi-gang HE Man-chao ZHENG Bo-wen JING Hong-wen REN Shu-lin ZHANG Qiang MENG Bo BAI Dong-feng WU Sai-sai WU Jiang-yu 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第7期2393-2410,共18页
A comprehensive understanding of the dynamic frictional characteristics in rock joints under high normal load and strong confinement is essential for ensuring the safety of deep engineering construction and mitigating... A comprehensive understanding of the dynamic frictional characteristics in rock joints under high normal load and strong confinement is essential for ensuring the safety of deep engineering construction and mitigating geological disasters.This study conducted shear experiments on rough rock joints under displacement-controlled dynamic normal loads,investigating the shear behaviors of joints across varying initial normal loads,normal loading frequencies,and normal loading amplitudes.Experimental results showed that the peak/valley shear force values increased with initial normal loads and normal loading frequencies but showed an initial increase followed by a decrease with normal loading amplitudes.Dynamic normal loading can either increase or decrease shear strength,while this study demonstrates that higher frequencies lead to enhanced friction.Increased initial normal loading and normal loading frequency result in a gradual decrease in joint roughness coefficient(JRC)values of joint surfaces after shearing.Positive correlations existed between frictional energy dissipation and peak shear forces,while post-shear joint surface roughness exhibited a negative correlation with peak shear forces through linear regression analysis.This study contributes to a better understanding of the sliding responses and shear mechanical characteristics of rock joints under dynamic disturbances. 展开更多
关键词 dynamic normal displacement shear strength variations phase lag phenomenon STICK-SLIP
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A novel mitigation measure for normal fault-induced deformations on pile-raft systems
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作者 Mohammadreza Jahanshahi Nowkandeh Mehdi Ashtiani 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第1期15-33,共19页
Evidence from recent earthquakes has shown destructive consequences of fault-induced permanent ground movement on structures.Such observations have increased the demand for improvements in the design of structures tha... Evidence from recent earthquakes has shown destructive consequences of fault-induced permanent ground movement on structures.Such observations have increased the demand for improvements in the design of structures that are dramatically vulnerable to surface fault ruptures.In this study a novel connection between the raft and the piles is proposed to mitigate the hazards associated with a normal fault on pile-raft systems by means of 3D finite element(FE)modeling.Before embarking on the parametric study,the strain-softening constitutive law used for numerical modeling of the sand has been validated against centrifuge test results.The exact location of the fix-head and unconnected pile-raft systems relative to the outcropping fault rupture in the free-field is parametrically investigated,revealing different failure mechanisms.The performance of the proposed connection for protecting the pile-raft system against normal fault-induced deformations is assessed by comparing the geotechnical and structural responses of both types of foundation.The results indicate that the pocket connection can relatively reduce the cap rotation and horizontal and vertical displacements of the raft in most scenarios.The proposed connection decreases the bending moment response of the piles to their bending moment capacity,verging on a fault offset of 0.6 m at bedrock. 展开更多
关键词 normal fault rupture failure mechanism pile-raft system pocket connection finite element modeling
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Depth-Guided Vision Transformer With Normalizing Flows for Monocular 3D Object Detection
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作者 Cong Pan Junran Peng Zhaoxiang Zhang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期673-689,共17页
Monocular 3D object detection is challenging due to the lack of accurate depth information.Some methods estimate the pixel-wise depth maps from off-the-shelf depth estimators and then use them as an additional input t... Monocular 3D object detection is challenging due to the lack of accurate depth information.Some methods estimate the pixel-wise depth maps from off-the-shelf depth estimators and then use them as an additional input to augment the RGB images.Depth-based methods attempt to convert estimated depth maps to pseudo-LiDAR and then use LiDAR-based object detectors or focus on the perspective of image and depth fusion learning.However,they demonstrate limited performance and efficiency as a result of depth inaccuracy and complex fusion mode with convolutions.Different from these approaches,our proposed depth-guided vision transformer with a normalizing flows(NF-DVT)network uses normalizing flows to build priors in depth maps to achieve more accurate depth information.Then we develop a novel Swin-Transformer-based backbone with a fusion module to process RGB image patches and depth map patches with two separate branches and fuse them using cross-attention to exchange information with each other.Furthermore,with the help of pixel-wise relative depth values in depth maps,we develop new relative position embeddings in the cross-attention mechanism to capture more accurate sequence ordering of input tokens.Our method is the first Swin-Transformer-based backbone architecture for monocular 3D object detection.The experimental results on the KITTI and the challenging Waymo Open datasets show the effectiveness of our proposed method and superior performance over previous counterparts. 展开更多
关键词 Monocular 3D object detection normalizing flows Swin Transformer
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Neuroimaging in atypical normal tension glaucoma:debating routine implementation in the absence of classic neurological findings
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作者 Umay Güvenç Gülizar Demirok +1 位作者 Güner Üney Selma Uzman 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期509-517,共9页
●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTG)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was... ●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTG)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was conducted on 90 atypical NTG patients who underwent cranial magnetic resonance imaging(MRI)due to atypical symptoms.The demographic characteristics,clinical parameters,and radiological findings were recorded.●RESULTS:Among the patients,66.7%had abnormal radiology results,with the most common findings being gliosis(34.4%),sequelae of cerebrovascular events and vascular malformations(14.4%),and benign intracranial mass lesions(11%).Non-glaucomatous visual field defects were more frequently observed in patients with abnormal neuroimaging results.However,there were no significant differences in intraocular pressure,optic disc parameters,retinal nerve fiber layer thickness,and visual field indices between patients with normal and abnormal radiological results.The mean age of the patients was 58.74y.Interestingly,there was a significant age difference,with the abnormal radiology group having a higher median age(P=0.021).●CONCLUSION:The study highlights the importance of cranial imaging in older NTG patients to detect underlying pathologies and prevent misdiagnosis.It suggests that neuroimaging may be warranted in NTG patients with atypical visual field defects incompatible with glaucoma.However,routine neuroimaging in all NTG patients without classic neurological signs may not be necessary. 展开更多
关键词 normal tension glaucoma NEUROIMAGING atypical visual field defects
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Shear band evolution and acoustic emission characteristics of sandstone containing non-persistent flaws
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作者 Shuting Miao Peng-Zhi Pan +1 位作者 Chuanqing Zhang Lei Huo 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第2期497-513,共17页
Direct shear tests were conducted on sandstone specimens under different constant normal stresses to study the coalescence of cracks between non-persistent flaws and the shear sliding characteristics of the shear-form... Direct shear tests were conducted on sandstone specimens under different constant normal stresses to study the coalescence of cracks between non-persistent flaws and the shear sliding characteristics of the shear-formed fault.Digital image correlation and acoustic emission(AE)techniques were used to monitor the evolution of shear bands at the rock bridge area and microcracking behaviors.The experimental results revealed that the shear stresses corresponding to the peak and sub-peak in the stressdisplacement curve are significantly affected by the normal stress.Strain localization bands emerged at both the tip of joints and the rock bridge,and their extension and interaction near the peak stress caused a surge in the AE hit rate and a significant decrease in the AE b value.Short and curvilinear strain bands were detected at low normal stress,while high normal stress generally led to more microcracking events and longer coplanar cracks at the rock bridge area.Furthermore,an increase in normal stress resulted in a higher AE count rate and more energetic AE events during friction sliding along the shearformed fault.It was observed that the elastic energy released during the crack coalescence at the prepeak stage was much greater than that released during friction sliding at the post-peak stage.More than 75%of AE events were located in the low-frequency band(0e100 kHz),and this proportion continued to rise with increasing normal stress.Moreover,more AE events of low AF value and high RA value were observed in specimens subjected to high normal stress,indicating that greater normal stress led to more microcracks of shear nature. 展开更多
关键词 Shear band evolution Acoustic emission(AE) Crack coalescence normal stress Shear sliding
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Normalized glandular dose coefficients for digital breast tomosynthesis using detailed Chinese breast models
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作者 Jia-Hao Wang Rui Qiu +4 位作者 An-Kang Hu Ye-Qi Liu Zhen Wu Hui Zhang Jun-Li Li 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第5期42-59,共18页
The rise in breast cancer diagnoses among Chinese women has necessitated the use of X-ray breast screening,which carries a radiation risk.This study aimed to provide a dosimetry protocol for the Chinese female populat... The rise in breast cancer diagnoses among Chinese women has necessitated the use of X-ray breast screening,which carries a radiation risk.This study aimed to provide a dosimetry protocol for the Chinese female population to replace the traditional standard that utilizes simplified breast models,for the accurate estimation of the mean glandular dose of a patient undergoing digital breast tomosynthesis(DBT).The first set of detailed Chinese female breast models and representative breast parameters was constructed.Considering backscatter radiation and computational efficiency,we improved the combination of these models and the Chinese reference adult female whole-body voxel phantom.Image acquisition for four commercial DBT systems that are widely employed in China was simulated using the Monte Carlo method to obtain the normalized glandular dose coefficients of DBT(D_(gN)^(DBT))and the glandular depth dose(D_(g)^(dep)(z))for different breast characteristics and X-ray spectra.We calculated a series of D_(gN)^(DBT) values for breasts with different percentage mass glandularities(5%,25%,50%,75%,and 100%)and compressed breast thicknesses(2,3,4,5,6,and 7 cm)at various tube potentials(25,28,30,32,35,and 49 kV)and target/filter combinations(W/Rh,W/Al,Mo/Mo,Rh/Rh,and Rh/Ag).The parameter dependence of the breast characteristics and beam conditions on D_(gN)^(DBT) in detailed breast models was investigated.The D_(gN)^(DBT) results were 14.6-51.0%lower than those of the traditional dosimetry standard in China.The difference in D_(gN)^(DBT) was mainly due to a decrease in the depth of the main energy deposition area caused by the glandular distribution along the depth direction.The results obtained in this study may be used to improve breast dosimetry in China and provide more detailed information on risk assessment during DBT. 展开更多
关键词 Digital breast tomosynthesis normalized glandular dose coefficients Detailed breast model Monte Carlo simulation
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Strategies for Cultivating Public Funded Targeted Normal Students Based on Goal Management Theory : A Case Study of East, West and North Guangdong
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作者 Yiqiong HUANG 《Meteorological and Environmental Research》 2024年第3期36-41,共6页
Public funded targeted normal students are an important component of China's teacher team construction.Since its implementation in 2007,a large number of outstanding rural teachers who have been striving on the fr... Public funded targeted normal students are an important component of China's teacher team construction.Since its implementation in 2007,a large number of outstanding rural teachers who have been striving on the front line of education have been trained.Based on the theory of goal management,this paper explores the problems and countermeasures in the training of public funded targeted normal students.It strives to solve the problems of low willingness to teach and high default rates among public funded normal students,and hopes that the suggestions proposed in this paper can further promote the effective implementation of policies for public funded normal students. 展开更多
关键词 Goal management Public funded targeted normal students Selection of normal students Training of normal students
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MULTIPLICITY OF NORMALIZED SOLUTIONS FOR THE FRACTIONAL SCHR?DINGER-POISSON SYSTEM WITH DOUBLY CRITICAL GROWTH
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作者 孟禹希 贺小明 《Acta Mathematica Scientia》 SCIE CSCD 2024年第3期997-1019,共23页
In this paper,we are concerned with solutions to the fractional Schrodinger-Poisson system■ with prescribed mass ∫_(R^(3))|u|^(2)dx=a^(2),where a> 0 is a prescribed number,μ> 0 is a paremeter,s ∈(0,1),2 <... In this paper,we are concerned with solutions to the fractional Schrodinger-Poisson system■ with prescribed mass ∫_(R^(3))|u|^(2)dx=a^(2),where a> 0 is a prescribed number,μ> 0 is a paremeter,s ∈(0,1),2 <q <2_(s)^(*),and 2_(s)^(*)=6/(3-2s) is the fractional critical Sobolev exponent.In the L2-subcritical case,we show the existence of multiple normalized solutions by using the genus theory and the truncation technique;in the L^(2)-supercritical case,we obtain a couple of normalized solutions by developing a fiber map.Under both cases,to recover the loss of compactness of the energy functional caused by the doubly critical growth,we need to adopt the concentration-compactness principle.Our results complement and improve upon some existing studies on the fractional Schrodinger-Poisson system with a nonlocal critical term. 展开更多
关键词 fractional Schrodinger-Poisson system normalized solutions variational methods L^(2)-subcritical L^(2)-supercritical
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Geometry and 3D seismic characterisation of post-rift normal faults in the Pearl River Mouth Basin,northern South China Sea
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作者 Yuanhang Liu Jinwei Gao +2 位作者 Wanli Chen Jiliang Wang Umair Khan 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2024年第4期25-39,共15页
Based on high-resolution 3D seismic data acquired in the Pearl(Zhujiang)River Mouth Basin of the northern South China Sea,this study investigated the geometry,spatial extension,and throw distribution of the post-rift ... Based on high-resolution 3D seismic data acquired in the Pearl(Zhujiang)River Mouth Basin of the northern South China Sea,this study investigated the geometry,spatial extension,and throw distribution of the post-rift normal fault through detailed seismic interpretation and fault modeling.A total of 289 post-rift normal faults were identified in the study area and can be classified into four types:(1)isolated normal faults above the carbonate platform;(2)isolated normal faults cutting through the carbonate platform;(3)conjugate normal faults,and(4)connecting normal faults.Throw distribution analysis on the fault planes show that the vertical throw profiles of most normal fault exhibit flat-topped profiles.Isolated normal faults above the carbonate platform exhibit roughly concentric ellipses with maximum throw zones in the central section whereas the normal faults cutting through the carbonate platform miss the lowermost section due to the chaotic seismic reflections in the interior of the carbonate platform.The vertical throws of conjugate normal faults anomalously decrease toward their intersection region on the fault plane whereas the connecting normal faults present two maximum throw zones in the central section of the fault plane.According to the symmetric elliptical distribution model of fault throw,an estimation was made indicating that normal faults cutting through the carbonate platform extended downward between-1308 s and-1780 s(two-way travel time)in depth and may not penetrate the entire Liuhua carbonate platform.Moreover,it is observed that the distribution of karst caves on the top of the carbonate platform disaccord with those of hydrocarbon reservoirs and the post-rift normal faults cutting through the carbonate platform in the study area.We propose that these karst caves formed most probably by corrosive fluids derived from magmatic activities during the Dongsha event,rather than pore waters or hydrocarbons. 展开更多
关键词 Post-rift normal faults fault throw Karst caves Corrosive fluids Pearl River Mouth Basin South China Sea
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Metabolic dysfunction-associated steatotic liver disease:The question of long-term high-normal alanine aminotransferase as a screening test
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作者 Terence N Moyana 《World Journal of Gastroenterology》 SCIE CAS 2024年第42期4576-4582,共7页
The growing prevalence of metabolic dysfunction-associated steatotic liver disease(MASLD)is being driven by the obesity epidemic.The quest for solutions continues particularly with regard to early detection.This edito... The growing prevalence of metabolic dysfunction-associated steatotic liver disease(MASLD)is being driven by the obesity epidemic.The quest for solutions continues particularly with regard to early detection.This editorial comments on the utility of long-term high-normal alanine aminotransferase(ALT)in screening for MASLD.Chen et al found that new onset MASLD can be detected by repetitively high normal ALT.Implicit in this concept is the question of what should be the accepted upper limit of normal(ULN)for ALT.It was previously set at 40 IU/L based on studies that included people with subclinical liver disease but the new consensus is 30/19 U/L in healthy males/females.Thus,when Chen et al defines the ULN as 40 U/L,others may view it as excessively high.It is important to recognize the variables affecting ULN e.g.instrumentation,diurnal variations,exercise and ageing.These variables matter when the distinctions are subtle e.g.normal vs high-normal.In this regard,the utility of long-term high normal ALT as a disease marker could be enhanced by combining it with other biomarkers,imaging and MASLD genetics to create machine learning classifiers.All in all,Chen et al’s work on long-term high normal ALT as a marker of new-onset MASLD deserves merit. 展开更多
关键词 Metabolic dysfunction-associated steatotic liver disease Alanine aminotransferase PATHOPHYSIOLOGY Screening Upper limit of normal Biomarkers Predictive models
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A Normalizing Flow-Based Bidirectional Mapping Residual Network for Unsupervised Defect Detection
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作者 Lanyao Zhang Shichao Kan +3 位作者 Yigang Cen Xiaoling Chen Linna Zhang Yansen Huang 《Computers, Materials & Continua》 SCIE EI 2024年第2期1631-1648,共18页
Unsupervised methods based on density representation have shown their abilities in anomaly detection,but detection performance still needs to be improved.Specifically,approaches using normalizing flows can accurately ... Unsupervised methods based on density representation have shown their abilities in anomaly detection,but detection performance still needs to be improved.Specifically,approaches using normalizing flows can accurately evaluate sample distributions,mapping normal features to the normal distribution and anomalous features outside it.Consequently,this paper proposes a Normalizing Flow-based Bidirectional Mapping Residual Network(NF-BMR).It utilizes pre-trained Convolutional Neural Networks(CNN)and normalizing flows to construct discriminative source and target domain feature spaces.Additionally,to better learn feature information in both domain spaces,we propose the Bidirectional Mapping Residual Network(BMR),which maps sample features to these two spaces for anomaly detection.The two detection spaces effectively complement each other’s deficiencies and provide a comprehensive feature evaluation from two perspectives,which leads to the improvement of detection performance.Comparative experimental results on the MVTec AD and DAGM datasets against the Bidirectional Pre-trained Feature Mapping Network(B-PFM)and other state-of-the-art methods demonstrate that the proposed approach achieves superior performance.On the MVTec AD dataset,NF-BMR achieves an average AUROC of 98.7%for all 15 categories.Especially,it achieves 100%optimal detection performance in five categories.On the DAGM dataset,the average AUROC across ten categories is 98.7%,which is very close to supervised methods. 展开更多
关键词 Anomaly detection normalizing flow source domain feature space target domain feature space bidirectional mapping residual network
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Normalized Ground State Solutions of Nonlinear Choquard Equations with Nonconstant Potential
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作者 LI Nan ZHAO Hui-yan XU Li-ping 《Chinese Quarterly Journal of Mathematics》 2024年第3期250-261,共12页
In this paper,we mainly focus on the following Choquard equation-{△u-V(x)(I_(a*)|u|^(p))|u|^(p-2)u=λu,x∈R^(N),u∈H^(1)(R^(N))where N≥1,λ∈R will arise as a Lagrange multiplier,0<a<N and N+a/N<p<N+a+2/... In this paper,we mainly focus on the following Choquard equation-{△u-V(x)(I_(a*)|u|^(p))|u|^(p-2)u=λu,x∈R^(N),u∈H^(1)(R^(N))where N≥1,λ∈R will arise as a Lagrange multiplier,0<a<N and N+a/N<p<N+a+2/N Under appropriate hypotheses on V(x),we prove that the above Choquard equation has a normalized ground state solution by utilizing variational methods. 展开更多
关键词 Choquard equation Nonconstant potential function normalized ground state solutions Variational methods
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Unveiling the silent link:Normal-tension glaucoma's enigmatic bond with cardiac blood flow
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作者 Prasanna Venkatesh Ramesh Arvind Kumar Morya +5 位作者 Ajanya K Aradhya Pavithra Pannerselvam Sai Thaejesvi Gopalakrishnan Shruthy Vaishali Ramesh Aji Kunnath Devadas Navaneeth Krishna 《World Journal of Cardiology》 2024年第1期10-15,共6页
This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers alike.NTG,ch... This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers alike.NTG,characterized by optic nerve damage and visual field loss despite normal intraocular pressure,has long puzzled clinicians.One emerging perspective suggests that alterations in ocular blood flow,particularly within the optic nerve head,may play a pivotal role in its pathogenesis.While NTG shares commonalities with its high-tension counterpart,its unique pathogenesis and potential ties to cardiovascular health make it a fascinating subject of exploration.It navigates through the complex web of vascular dysregulation,blood pressure and perfusion pressure,neurovascular coupling,and oxidative stress,seeking to uncover the hidden threads that tie the heart and eyes together in NTG.This review explores into the intricate mechanisms connecting cardiovascular factors to NTG,shedding light on how cardiac dynamics can influence ocular health,particularly in cases where intraocular pressure remains within the normal range.NTG's enigmatic nature,often characterized by seemingly contradictory risk factors and clinical profiles,underscores the need for a holistic approach to patient care.Drawing parallels to cardiac health,we examine into the shared vascular terrain connecting the heart and the eyes.Cardiovascular factors,including systemic blood flow,endothelial dysfunction,and microcirculatory anomalies,may exert a profound influence on ocular perfusion,impacting the delicate balance within the optic nerve head.By elucidating the subtle clues and potential associations between cardiology and NTG,this review invites clinicians to consider a broader perspective in their evaluation and management of this elusive condition.As the understanding of these connections evolves,so too may the prospects for early diagnosis and tailored interventions,ultimately enhancing the quality of life for those living with NTG. 展开更多
关键词 normal tension glaucoma Vascular dysregulation Ocular blood flow Blood pressure Perfusion pressure Oxidative stress
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Stroke Patients’ Reintegration into Normal Living Post-Discharge from Inpatient Rehabilitation: An Integrative Review
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作者 Eric F. Tanlaka Omotunmise Agbeyangi +1 位作者 Adam Mulcaster Edward Cruz 《Open Journal of Therapy and Rehabilitation》 2024年第3期274-300,共27页
Background: Stroke rehabilitation professionals have historically focused rehabilitation on physical functions and overlooked the concept of community reintegration after discharge from inpatient rehabilitation. The l... Background: Stroke rehabilitation professionals have historically focused rehabilitation on physical functions and overlooked the concept of community reintegration after discharge from inpatient rehabilitation. The lack of focus on psychosocial functions post-stroke may lead to lower levels of satisfaction during community reintegration. Methods: This integrative review synthesized findings from research literature on stroke patients’ reintegration into the community after inpatient rehabilitation to address three research questions: a) What specific physical and psychosocial functions have been identified as predictors of successful reintegration into normal living after stroke?, b) How do physical and psychosocial functions promote successful reintegration into normal living after stroke?, and c) What factors have been identified that hinder stroke patients’ reintegration into normal living after stroke? Results: A systematic search of literature identified sixteen studies that provided significant context for the research questions. What physical and psychosocial functions of stroke patients included, for example, improved mobility, independence in daily activities, reduced disability, psychological well-being, self-efficacy, social support, and personal relationships. How physical and psychosocial functions promote reintegration included, for example, disability management, emotional well-being, self-care independence, sense of purpose, and employment influence. Factors that hinder stroke patients’ reintegration consisted of longer stride time, impaired balance/mobility, activities limitation, severe stroke, presence of comorbidity, depressive symptoms, speech and language challenges, inadequate self-efficacy, fear of falling, older age, low educational level, lack of social support, and social isolation. Conclusion: Successful community reintegration after stroke requires a shift of focus from rehabilitation interventions that target physical functions to include interventions that address psychosocial functions. 展开更多
关键词 STROKE Outpatient Rehabilitation Community Reintegration normal Living Functional Abilities
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