BACKGROUND Current concepts of beauty are increasingly subjective,influenced by the viewpoints of others.The aim of the study was to evaluate divergences in the perception of dental appearance and smile esthetics amon...BACKGROUND Current concepts of beauty are increasingly subjective,influenced by the viewpoints of others.The aim of the study was to evaluate divergences in the perception of dental appearance and smile esthetics among patients,laypersons and dental practitioners.The study goals were to evaluate the influence of age,sex,education and dental specialty on the participants’judgment and to identify the values of different esthetic criteria.Patients sample included 50 patients who responded to a dental appearance questionnaire(DAQ).Two frontal photographs were taken,one during a smile and one with retracted lips.Laypersons and dentists were asked to evaluate both photographs using a Linear Scale from(0-10),where 0 represent(absolutely unaesthetic)and 10 represent(absolutely aesthetic).One-way analysis of variance(ANOVA)and t-test analysis were measured for each group.Most patients in the sample expressed satisfaction with most aspects of their smiles and dental appearance.Among laypersons(including 488 participants),47 pictures“with lips”out of 50 had higher mean aesthetic scores compared to pictures“without lips”.Among the dentist sample,90 dentists’perception towards the esthetic smile and dental appearance for photos“with lips”and“without lips”were the same for 23 out of 50 patients.Perception of smile aesthetics differed between patients,laypersons and dentists.Several factors can contribute to shape the perception of smile aesthetic.AIM To compare the perception of dental aesthetic among patients,laypersons,and professional dentists,to evaluate the impact of age,sex,educational background,and income on the judgments made by laypersons,to assess the variations in experience,specialty,age,and sex on professional dentists’judgment,and to evaluate the role of lips,skin shade and tooth shade in different participants’judgments.METHODS Patients sample included 50 patients who responded to DAQ.Two frontal photographs were taken:one during a smile and one with retracted lips.Laypersons and dentists were asked to evaluate both photographs using a Linear Scale from(0-10),where 0 represent(absolutely unaesthetic)and 10 represent(absolutely aesthetic).One-way ANOVA and t-test analysis were measured for each group.RESULTS Most patients in the sample expressed satisfaction with most aspects of their smiles and dental appearance.Among laypersons(including 488 participants),47 pictures“with lips”out of 50 had higher mean aesthetic scores compared to pictures“without lips”.Whereas among the dentist sample,90 dentists’perception towards the esthetic smile and dental appearance for photos“with lips”and“without lips”were the same for 23 out of 50 patients.Perception of smile aesthetics differed between patients,laypersons and dentists.CONCLUSION Several factors can contribute to shape the perception of smile aesthetic.展开更多
This study examined the non-medical factors that influence expectant mothers to opt for caesarean deliveries in Ghana. Data on 395 expectant mothers across the ten regions of Ghana who were located in urban, semi-rura...This study examined the non-medical factors that influence expectant mothers to opt for caesarean deliveries in Ghana. Data on 395 expectant mothers across the ten regions of Ghana who were located in urban, semi-rural and rural areas, and spanned a period of five years (from 2012 to 2016) were obtained from the Ghana Health Service. In fitting the logistic regression model, data on 355 expectant mothers (i.e. 89.9% of the data) was assigned to the analysis sample while 40 (i.e. 10.1%) was assigned to the hold-out sample. The hold-out sample together with other statistical measures of overall model fit, pseudo R2 measures and classification accuracy were used to validate the results obtained from the analysis sample. Significance was tested at p = 0.05. Determinants including, educational level of expectant mother, parity of expectant mother, baby’s birth weight, previous caesarean delivery, location of expectant mother, age of expectant mother and, period within the year of childbirth had a significant effect on caesarean delivery. The study recommended that health practitioners should be able to foretell expectant mothers who are likely to undergo caesarean delivery in order for them to prepare financially and psychologically to avoid further complications. Due to the significant positive attitude of women towards caesarean delivery rather than normal delivery, it is necessary to inform them about the advantages of normal delivery and the health hazards associated with caesarean delivery to the mother and child.展开更多
Background:During these moments of anxiety,fear and to some extent despair,it is imperative for everyone to have access to the right information.This can be achieved through breaking down the science and medical termi...Background:During these moments of anxiety,fear and to some extent despair,it is imperative for everyone to have access to the right information.This can be achieved through breaking down the science and medical terminologies used to express the scenarios emanating from the COVID-19 pandemic.Forward:This commentary focuses on the most asked questions that,when not answered with scientific grounds to convince the non-medics can result in non-science based“infodemics”.The brief history behind COVID-19 pandemic,the science of SARS-CoV-2,the taxonomies used,a brief on the Pathophysiology of SARS-CoV-2,the genetic make up,most vulnerable indivduals,antibodies against COVID-19,mother to baby transmission,conspiracy theories reagading the virus being weaponized,mutations occurring with SARS-CoV-2 and reoccurrence of COVID-19 in the future are all explained at great length.The review made references to the existing publications regarding this pandemic.Conclusion:While the science regarding this virus is not exhausted,we confirmed that,the knowledge gap between non-medics and medics is wide.The results emerging from the pandemic to form data are questionable,so it is our collective responsibility to fight against this virus in order to stop further spreading by providing the right information to the public.If we would not come together to fight and win this battle,we might be witnessing many large cities turning into emerging epicenters of COVID-19.展开更多
BACKGROUND: Few studies have examined the association of layperson characteristics with cardiopulmonary resuscitation(CPR) provision. Previous studies suggested provider characteristics, including age and gender, were...BACKGROUND: Few studies have examined the association of layperson characteristics with cardiopulmonary resuscitation(CPR) provision. Previous studies suggested provider characteristics, including age and gender, were associated with CPR quality, particularly chest compression(CC) depth. We sought to determine the association of subject characteristics, including age and gender with layperson CPR quality during an unannounced simulated CPR event. We hypothesized shallower CC depth in females, and older-aged subjects.METHODS: As part of a larger multicenter randomized controlled trial of CPR training for cardiac patients' caregivers, CPR skills were assessed 6 months after training. We analyzed associations between subject characteristics and CC rate, CC depth and no-? ow time. Each variable was analyzed independently; signi? cant predictors determined via univariate analysis were assessed in a multivariate regression model.RESULTS: A total of 521 laypersons completed a 6-month CPR skills assessment and were included in the analysis. Mean age was 51.8±13.7 years, 75% were female, 57% were Caucasian. Overall, mean CC rate was 88.5±25.0 per minute, CC depth was 50.9±2.0 mm, and mean no-flow time was 15.9±2.7 sec/min. CC depth decreased signi? cantly in subjects >62 years(P<0.001). Male subjects performed deeper CCs than female subjects(47.5±1.7 vs. 41.9±0.6, P<0.001).CONCLUSION: We found that layperson age >62 years and female gender are associated with shallower CC depth.展开更多
BACKGROUND:Diverse models of automated external defibrillators(AEDs)possess distinctive features.This study aimed to investigate whether laypersons trained with one type of AED could intelligently use another initial ...BACKGROUND:Diverse models of automated external defibrillators(AEDs)possess distinctive features.This study aimed to investigate whether laypersons trained with one type of AED could intelligently use another initial contact type of AED with varying features.METHODS:This was a prospective crossover simulation experimental study conducted among college students.Subjects were randomly trained with either AED1(AED1 group)or AED2(AED2 group),and the AED operation performance was evaluated individually(Phase I test).At the 6-month follow-up AED performance test(Phase II test),half of the subjects were randomly switched to use another type of AED,which formed two switches(Switch A:AED1-1 group vs.AED2-1 group;Switch B:AED2-2 group vs.AED1-2 group).RESULTS:A total of 224 college students participated in the study.In the phase I test,a significantly higher proportion of successful defibrillation and shorter shock delivery time to achieve successful defibrillation was observed in the AED2 group than in the AED1 group.In the phase II test,no statistical differences were observed in the proportion of successful defibrillation in Switch A(51.4%vs.36.6%,P=0.19)and Switch B(78.0%vs.53.7%,P=0.08).The median shock delivery time within participants achieving successful defibrillation was significantly longer in the switched group than that of the initial group in both Switch A(89[81-107]s vs.124[95-135]s,P=0.006)and Switch B(68[61.5-81.5]s vs.95.5[55-131]s,P<0.001).CONCLUSION:College students were able to effectively use AEDs different from those used in the initial training after six months,although the time to shock delivery was prolonged.展开更多
Objective:The number of liver cancer patients in China accounts for more than half of the world.However,China currently lacks national,multicenter economic burden data,and meanwhile,measuring the differences among dif...Objective:The number of liver cancer patients in China accounts for more than half of the world.However,China currently lacks national,multicenter economic burden data,and meanwhile,measuring the differences among different subgroups will be informative to formulate corresponding policies in liver cancer control.Thus,the aim of the study was to measure the economic burden of liver cancer by various subgroups.Methods:A hospital-based,multicenter and cross-sectional survey was conducted during 2012・2014,covering 39 hospitals and 21 project sites in 13 provinces across China.The questionnaire covers clinical information,sociology,expenditure,and related variables.All expenditure data were reported in Chinese Yuan(CNY)using 2014 values.Results:A total of 2,223 liver cancer patients were enrolled,of whom 59.61%were late-stage cases(III-IV),and 53.8%were hepatocellular carcinoma.The average total expenditure per liver cancer patient was estimated as 53,220 CNY,including 48,612 CNY of medical expenditures(91.3%)and 4,608 CNY of non-medical expenditures(8.7%).The average total expenditures in stage I,H,m and stage IV were 52,817 CNY,50,877 CNY,50,678 CNY and 54,089 CNY(P>0.05),respectively.Non-medical expenditures including additional meals,additional nutrition care,transportation,accommodation and hired informal nursing were 1,453 CNY,839 CNY,946 CNY,679 CNY and 200 CNY,respectively.The one-year out-of-pocket expenditure of a newly diagnosed patient was 24,953 CNY,and 77.2%of the patients suffered an unmanageable financial burden.Multivariate analysis showed that overall expenditure differed in almost all subgroups(P<0.05),except for sex,clinical stage,and pathologic type.Conclusions:There was no difference in treatment expenditure for liver cancer patients at different clinical stages,which suggests that maintaining efforts on treatment efficacy improvement is important but not enough.To fiirtherly reduce the overall economic burden from liver cancer,more effort should be given to primary and secondary prevention strategies.展开更多
Background:Treatment of tuberculosis(TB)in China is partially covered by national programs and health insurance schemes,though TB patients often face considerable medical expenditures.For some,especially those from po...Background:Treatment of tuberculosis(TB)in China is partially covered by national programs and health insurance schemes,though TB patients often face considerable medical expenditures.For some,especially those from poorer households,non-medical costs,such as transport,accommodation,and nutritional supplementation may be a substantial additional burden.In this article we aim to evaluate these non-medical costs induced by seeking TB care using data from a large scale cross-sectional survey.Methods:A total of 797 TB cases from three cities were randomly selected using a stratified cluster sampling design.Inpatient medical costs,outpatient medical costs,and direct non-medical costs related to TB treatment were collected using in-person interviews by trained interviewers.Mean and median non-medical costs for different sub-groups were calculated and compared using Kruskal-Wallis and Mann–Whitney U tests.Regression analysis was conducted to assess the influence of different patient characteristics on total non-medical cost.Results:The median non-medical cost was RMB 1429,with interquartile range RMB 424–2793.The median non-medical costs relating to inpatient treatment,outpatient treatment,and additional nutrition supplementation were RMB 540,91,and 900,respectively.Of the 797 cases,20%reported catastrophic expenditure on non-medical costs.Statistically significant differences were detected between different cities,age groups,geographical locations,inpatient/outpatient care,education levels and family income groups.Conclusions:Non-medical costs relating to TB treatment are a serious financial burden for many TB patients.Financial assistance that can limit this burden is urgently needed during the treatment period,especially for the poor.展开更多
Madhuca longifolia(M. longifolia) is also known as Mahua belonging to the family sapoteace family. M. longifolia is used in traditional and folklore system of medicine widely across India, Nepal, and Sri Lanka for its...Madhuca longifolia(M. longifolia) is also known as Mahua belonging to the family sapoteace family. M. longifolia is used in traditional and folklore system of medicine widely across India, Nepal, and Sri Lanka for its various pharmacological properties as in snake bites and in diabetes. Phytochemicals studies documented the different bioactive constituents, namely,glycosides, flavonoids, terpenes and saponins. The pharmacological studies proved that it possess wide range of biological activities such as antiulcer, antiinflammatory, antioxidant and antidiabetic activities. The toxicity studies reveal its non-toxic effect even at larger doses.Thus M. longifolia can be considered as a therapeutic agent for specific diseases. Scientific investigation on various isolated bioactive components and its efficacy on diseases proved the future usefulness of different species of Madhuca. This review summarizes the phytochemical,pharmacological, medicinal and non-medicinal uses of M. longifolia. Further exploration on M.longifolia for its therapeutic potential is however required for depth traditional knowledge.展开更多
Ketamine is a dissociative anaesthetic.It is listed by the World Health Organisation[1]in its Model List of Essential Medicines,which are basic drugs required for any health-care system.Indeed,clinically ketamine poss...Ketamine is a dissociative anaesthetic.It is listed by the World Health Organisation[1]in its Model List of Essential Medicines,which are basic drugs required for any health-care system.Indeed,clinically ketamine possesses hypnotic,analgesic and amnesic effects.It is commonly used as induction展开更多
Introduction: Therapeutic patient education is a continuous, integrated, patient-centered process. A study was conducted in the Asthma School in the pneumophtisiology department of Senegal. Overall goal was to determi...Introduction: Therapeutic patient education is a continuous, integrated, patient-centered process. A study was conducted in the Asthma School in the pneumophtisiology department of Senegal. Overall goal was to determine the influence of therapeutic education on the quality of life of asthmatics. Method: Transverse study, descriptive and evaluative therapeutic education provided in the school of asthma on quality of life for asthma patients. Data were analyzed through IBM SPSS (Statistical Package for Social Science) version 20. Results: 100 asthmatic patients were included with a sex ratio of 0.37. The average age of the patients was 36.76 years old. The majority (81.3%) (n = 39) being new participants. The average scores for symptoms, exposure to stimuli, emotions and limiting activities stay higher for adherent patients as well as the score overall quality of life. Conclusion: The school of asthma, associated with the therapeutic management, can improve the control of the disease and the quality of life of the patient.展开更多
基金Princess Nourah Bint Abdulrahman University Researchers,No.PNURSP2024R115.
文摘BACKGROUND Current concepts of beauty are increasingly subjective,influenced by the viewpoints of others.The aim of the study was to evaluate divergences in the perception of dental appearance and smile esthetics among patients,laypersons and dental practitioners.The study goals were to evaluate the influence of age,sex,education and dental specialty on the participants’judgment and to identify the values of different esthetic criteria.Patients sample included 50 patients who responded to a dental appearance questionnaire(DAQ).Two frontal photographs were taken,one during a smile and one with retracted lips.Laypersons and dentists were asked to evaluate both photographs using a Linear Scale from(0-10),where 0 represent(absolutely unaesthetic)and 10 represent(absolutely aesthetic).One-way analysis of variance(ANOVA)and t-test analysis were measured for each group.Most patients in the sample expressed satisfaction with most aspects of their smiles and dental appearance.Among laypersons(including 488 participants),47 pictures“with lips”out of 50 had higher mean aesthetic scores compared to pictures“without lips”.Among the dentist sample,90 dentists’perception towards the esthetic smile and dental appearance for photos“with lips”and“without lips”were the same for 23 out of 50 patients.Perception of smile aesthetics differed between patients,laypersons and dentists.Several factors can contribute to shape the perception of smile aesthetic.AIM To compare the perception of dental aesthetic among patients,laypersons,and professional dentists,to evaluate the impact of age,sex,educational background,and income on the judgments made by laypersons,to assess the variations in experience,specialty,age,and sex on professional dentists’judgment,and to evaluate the role of lips,skin shade and tooth shade in different participants’judgments.METHODS Patients sample included 50 patients who responded to DAQ.Two frontal photographs were taken:one during a smile and one with retracted lips.Laypersons and dentists were asked to evaluate both photographs using a Linear Scale from(0-10),where 0 represent(absolutely unaesthetic)and 10 represent(absolutely aesthetic).One-way ANOVA and t-test analysis were measured for each group.RESULTS Most patients in the sample expressed satisfaction with most aspects of their smiles and dental appearance.Among laypersons(including 488 participants),47 pictures“with lips”out of 50 had higher mean aesthetic scores compared to pictures“without lips”.Whereas among the dentist sample,90 dentists’perception towards the esthetic smile and dental appearance for photos“with lips”and“without lips”were the same for 23 out of 50 patients.Perception of smile aesthetics differed between patients,laypersons and dentists.CONCLUSION Several factors can contribute to shape the perception of smile aesthetic.
文摘This study examined the non-medical factors that influence expectant mothers to opt for caesarean deliveries in Ghana. Data on 395 expectant mothers across the ten regions of Ghana who were located in urban, semi-rural and rural areas, and spanned a period of five years (from 2012 to 2016) were obtained from the Ghana Health Service. In fitting the logistic regression model, data on 355 expectant mothers (i.e. 89.9% of the data) was assigned to the analysis sample while 40 (i.e. 10.1%) was assigned to the hold-out sample. The hold-out sample together with other statistical measures of overall model fit, pseudo R2 measures and classification accuracy were used to validate the results obtained from the analysis sample. Significance was tested at p = 0.05. Determinants including, educational level of expectant mother, parity of expectant mother, baby’s birth weight, previous caesarean delivery, location of expectant mother, age of expectant mother and, period within the year of childbirth had a significant effect on caesarean delivery. The study recommended that health practitioners should be able to foretell expectant mothers who are likely to undergo caesarean delivery in order for them to prepare financially and psychologically to avoid further complications. Due to the significant positive attitude of women towards caesarean delivery rather than normal delivery, it is necessary to inform them about the advantages of normal delivery and the health hazards associated with caesarean delivery to the mother and child.
文摘Background:During these moments of anxiety,fear and to some extent despair,it is imperative for everyone to have access to the right information.This can be achieved through breaking down the science and medical terminologies used to express the scenarios emanating from the COVID-19 pandemic.Forward:This commentary focuses on the most asked questions that,when not answered with scientific grounds to convince the non-medics can result in non-science based“infodemics”.The brief history behind COVID-19 pandemic,the science of SARS-CoV-2,the taxonomies used,a brief on the Pathophysiology of SARS-CoV-2,the genetic make up,most vulnerable indivduals,antibodies against COVID-19,mother to baby transmission,conspiracy theories reagading the virus being weaponized,mutations occurring with SARS-CoV-2 and reoccurrence of COVID-19 in the future are all explained at great length.The review made references to the existing publications regarding this pandemic.Conclusion:While the science regarding this virus is not exhausted,we confirmed that,the knowledge gap between non-medics and medics is wide.The results emerging from the pandemic to form data are questionable,so it is our collective responsibility to fight against this virus in order to stop further spreading by providing the right information to the public.If we would not come together to fight and win this battle,we might be witnessing many large cities turning into emerging epicenters of COVID-19.
文摘BACKGROUND: Few studies have examined the association of layperson characteristics with cardiopulmonary resuscitation(CPR) provision. Previous studies suggested provider characteristics, including age and gender, were associated with CPR quality, particularly chest compression(CC) depth. We sought to determine the association of subject characteristics, including age and gender with layperson CPR quality during an unannounced simulated CPR event. We hypothesized shallower CC depth in females, and older-aged subjects.METHODS: As part of a larger multicenter randomized controlled trial of CPR training for cardiac patients' caregivers, CPR skills were assessed 6 months after training. We analyzed associations between subject characteristics and CC rate, CC depth and no-? ow time. Each variable was analyzed independently; signi? cant predictors determined via univariate analysis were assessed in a multivariate regression model.RESULTS: A total of 521 laypersons completed a 6-month CPR skills assessment and were included in the analysis. Mean age was 51.8±13.7 years, 75% were female, 57% were Caucasian. Overall, mean CC rate was 88.5±25.0 per minute, CC depth was 50.9±2.0 mm, and mean no-flow time was 15.9±2.7 sec/min. CC depth decreased signi? cantly in subjects >62 years(P<0.001). Male subjects performed deeper CCs than female subjects(47.5±1.7 vs. 41.9±0.6, P<0.001).CONCLUSION: We found that layperson age >62 years and female gender are associated with shallower CC depth.
基金National Natural Science Foundation of China(72074144,81703303)Innovative Research Team of High-level Local Universities in Shanghai(No.SHSMU-ZDCX20212801)approved by the Joint Research Ethics Board of the Shanghai Jiao Tong University School of Public Health and Nursing(SJUPN-201714).
文摘BACKGROUND:Diverse models of automated external defibrillators(AEDs)possess distinctive features.This study aimed to investigate whether laypersons trained with one type of AED could intelligently use another initial contact type of AED with varying features.METHODS:This was a prospective crossover simulation experimental study conducted among college students.Subjects were randomly trained with either AED1(AED1 group)or AED2(AED2 group),and the AED operation performance was evaluated individually(Phase I test).At the 6-month follow-up AED performance test(Phase II test),half of the subjects were randomly switched to use another type of AED,which formed two switches(Switch A:AED1-1 group vs.AED2-1 group;Switch B:AED2-2 group vs.AED1-2 group).RESULTS:A total of 224 college students participated in the study.In the phase I test,a significantly higher proportion of successful defibrillation and shorter shock delivery time to achieve successful defibrillation was observed in the AED2 group than in the AED1 group.In the phase II test,no statistical differences were observed in the proportion of successful defibrillation in Switch A(51.4%vs.36.6%,P=0.19)and Switch B(78.0%vs.53.7%,P=0.08).The median shock delivery time within participants achieving successful defibrillation was significantly longer in the switched group than that of the initial group in both Switch A(89[81-107]s vs.124[95-135]s,P=0.006)and Switch B(68[61.5-81.5]s vs.95.5[55-131]s,P<0.001).CONCLUSION:College students were able to effectively use AEDs different from those used in the initial training after six months,although the time to shock delivery was prolonged.
基金This study was supported by the State Key Projects Specialized on Infectious Diseases(No.2O17ZX1O2O12O1-008-002,No.2O17ZX1O2O12O1-OO6-OO3)Sanming Project of Medicine in Shenzhen(No.SZSM201911015)+2 种基金the National Natural Science Foundation of China(No.81974492,No.81773521)Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2019-I2M-2-004)the Natural Science Foundation of Guangdong Province(No.2020A151501478).
文摘Objective:The number of liver cancer patients in China accounts for more than half of the world.However,China currently lacks national,multicenter economic burden data,and meanwhile,measuring the differences among different subgroups will be informative to formulate corresponding policies in liver cancer control.Thus,the aim of the study was to measure the economic burden of liver cancer by various subgroups.Methods:A hospital-based,multicenter and cross-sectional survey was conducted during 2012・2014,covering 39 hospitals and 21 project sites in 13 provinces across China.The questionnaire covers clinical information,sociology,expenditure,and related variables.All expenditure data were reported in Chinese Yuan(CNY)using 2014 values.Results:A total of 2,223 liver cancer patients were enrolled,of whom 59.61%were late-stage cases(III-IV),and 53.8%were hepatocellular carcinoma.The average total expenditure per liver cancer patient was estimated as 53,220 CNY,including 48,612 CNY of medical expenditures(91.3%)and 4,608 CNY of non-medical expenditures(8.7%).The average total expenditures in stage I,H,m and stage IV were 52,817 CNY,50,877 CNY,50,678 CNY and 54,089 CNY(P>0.05),respectively.Non-medical expenditures including additional meals,additional nutrition care,transportation,accommodation and hired informal nursing were 1,453 CNY,839 CNY,946 CNY,679 CNY and 200 CNY,respectively.The one-year out-of-pocket expenditure of a newly diagnosed patient was 24,953 CNY,and 77.2%of the patients suffered an unmanageable financial burden.Multivariate analysis showed that overall expenditure differed in almost all subgroups(P<0.05),except for sex,clinical stage,and pathologic type.Conclusions:There was no difference in treatment expenditure for liver cancer patients at different clinical stages,which suggests that maintaining efforts on treatment efficacy improvement is important but not enough.To fiirtherly reduce the overall economic burden from liver cancer,more effort should be given to primary and secondary prevention strategies.
基金The study upon which this paper was written is part of the large program entitled“China National Health and Family Planning Commission and the Gates Foundation TB Project”-a collaboration between the Government of China and the Bill and Melinda Gates Foundation(Grant No.51914)implemented by the China Center of Disease Control and Prevention(CDC).
文摘Background:Treatment of tuberculosis(TB)in China is partially covered by national programs and health insurance schemes,though TB patients often face considerable medical expenditures.For some,especially those from poorer households,non-medical costs,such as transport,accommodation,and nutritional supplementation may be a substantial additional burden.In this article we aim to evaluate these non-medical costs induced by seeking TB care using data from a large scale cross-sectional survey.Methods:A total of 797 TB cases from three cities were randomly selected using a stratified cluster sampling design.Inpatient medical costs,outpatient medical costs,and direct non-medical costs related to TB treatment were collected using in-person interviews by trained interviewers.Mean and median non-medical costs for different sub-groups were calculated and compared using Kruskal-Wallis and Mann–Whitney U tests.Regression analysis was conducted to assess the influence of different patient characteristics on total non-medical cost.Results:The median non-medical cost was RMB 1429,with interquartile range RMB 424–2793.The median non-medical costs relating to inpatient treatment,outpatient treatment,and additional nutrition supplementation were RMB 540,91,and 900,respectively.Of the 797 cases,20%reported catastrophic expenditure on non-medical costs.Statistically significant differences were detected between different cities,age groups,geographical locations,inpatient/outpatient care,education levels and family income groups.Conclusions:Non-medical costs relating to TB treatment are a serious financial burden for many TB patients.Financial assistance that can limit this burden is urgently needed during the treatment period,especially for the poor.
文摘Madhuca longifolia(M. longifolia) is also known as Mahua belonging to the family sapoteace family. M. longifolia is used in traditional and folklore system of medicine widely across India, Nepal, and Sri Lanka for its various pharmacological properties as in snake bites and in diabetes. Phytochemicals studies documented the different bioactive constituents, namely,glycosides, flavonoids, terpenes and saponins. The pharmacological studies proved that it possess wide range of biological activities such as antiulcer, antiinflammatory, antioxidant and antidiabetic activities. The toxicity studies reveal its non-toxic effect even at larger doses.Thus M. longifolia can be considered as a therapeutic agent for specific diseases. Scientific investigation on various isolated bioactive components and its efficacy on diseases proved the future usefulness of different species of Madhuca. This review summarizes the phytochemical,pharmacological, medicinal and non-medicinal uses of M. longifolia. Further exploration on M.longifolia for its therapeutic potential is however required for depth traditional knowledge.
文摘Ketamine is a dissociative anaesthetic.It is listed by the World Health Organisation[1]in its Model List of Essential Medicines,which are basic drugs required for any health-care system.Indeed,clinically ketamine possesses hypnotic,analgesic and amnesic effects.It is commonly used as induction
文摘Introduction: Therapeutic patient education is a continuous, integrated, patient-centered process. A study was conducted in the Asthma School in the pneumophtisiology department of Senegal. Overall goal was to determine the influence of therapeutic education on the quality of life of asthmatics. Method: Transverse study, descriptive and evaluative therapeutic education provided in the school of asthma on quality of life for asthma patients. Data were analyzed through IBM SPSS (Statistical Package for Social Science) version 20. Results: 100 asthmatic patients were included with a sex ratio of 0.37. The average age of the patients was 36.76 years old. The majority (81.3%) (n = 39) being new participants. The average scores for symptoms, exposure to stimuli, emotions and limiting activities stay higher for adherent patients as well as the score overall quality of life. Conclusion: The school of asthma, associated with the therapeutic management, can improve the control of the disease and the quality of life of the patient.
