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Effectiveness and safety of early lens extraction during par plana vitrectomy for proliferative diabetes retinopathy with mild cataract:a randomized clinical trial
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作者 Wei-Bo Feng Lei Zheng +17 位作者 Ying-Qi Li Yong-Hao Li Guo-Ming Zhang Xian Wang Bing-Qian Liu Ling Jin Yi-Nuo Huang Yang-Fan Yang Zi-Dong Chen Da-Hui Ma Qing-Shan Chen Chao-Jun Qin Bing-Min Feng Zhu-Min Yang Xing Huang Cheng-Jie Yang Sheng-Hui Liu Ming-Xing Wu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期528-536,共9页
●AIM:To evaluate the effectiveness and safety of early lens extraction during pars plana vitrectomy(PPV)for proliferative diabetic retinopathy(PDR)compared to those of PPV with subsequent cataract surgery.●METHODS:T... ●AIM:To evaluate the effectiveness and safety of early lens extraction during pars plana vitrectomy(PPV)for proliferative diabetic retinopathy(PDR)compared to those of PPV with subsequent cataract surgery.●METHODS:This multicenter randomized controlled trial was conducted in three Chinese hospitals on patients with PDR,aged>45y,with mild cataracts.The participants were randomly assigned to the combined(PPV combined with simultaneously cataract surgery,i.e.,phacovitrectomy)or subsequent(PPV with subsequent cataract surgery 6mo later)group and followed up for 12mo.The primary outcome was the change in best-corrected visual acuity(BCVA)from baseline to 6mo,and the secondary outcomes included complication rates and medical expenses.●RESULTS:In total,129 patients with PDR were recruited and equally randomized(66 and 63 in the combined and subsequent groups respectively).The change in BCVA in the combined group[mean,36.90 letters;95%confidence interval(CI),30.35–43.45]was significantly better(adjusted difference,16.43;95%CI,8.77–24.08;P<0.001)than in the subsequent group(mean,22.40 letters;95%CI,15.55–29.24)6mo after the PPV,with no significant difference between the two groups at 12mo.The overall surgical risk of two sequential surgeries was significantly higher than that of the combined surgery for neovascular glaucoma(17.65%vs 3.77%,P=0.005).No significant differences were found in the photocoagulation spots,surgical time,and economic expenses between two groups.In the subsequent group,the duration of work incapacity(22.54±9.11d)was significantly longer(P<0.001)than that of the combined group(12.44±6.48d).●CONCLUSION:PDR patients aged over 45y with mild cataract can also benefit from early lens extraction during PPV with gratifying effectiveness,safety and convenience,compared to sequential surgeries. 展开更多
关键词 lens extraction pars plana vitrectomy proliferative diabetic retinopathy cataract simultaneously operations
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Analysis of Ultrasonic Emulsification Surgery and Small Incision Cataract Extracapsular Extraction Surgery for Cataract Clinical Treatment Level Improvement
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作者 Chunyan Ji 《Journal of Clinical and Nursing Research》 2024年第2期196-200,共5页
Objective:To analyze the efficacy of ultrasonic emulsification and small incision cataract extracapsular extraction in cataract patients.Methods:96 cataract patients admitted from May 2021 to May 2023 were selected an... Objective:To analyze the efficacy of ultrasonic emulsification and small incision cataract extracapsular extraction in cataract patients.Methods:96 cataract patients admitted from May 2021 to May 2023 were selected and randomly grouped into group A(ultrasonic emulsification)and group B(small-incision extracapsular cataract extraction),with 48 cases each.Results:At 1 week,1-month,and 3 months post-operation,the visual acuity of group A was higher and the astigmatism value was lower than that of group B(P<0.05);at 12h,24h,and 48h post-operation,the intraocular pressure of group A was higher than that of group B(P<0.05);the thickness of macular area of group A was lower than that of group B at 1 week and 1-month post-operation(P<0.05).Conclusion:Ultrasonic emulsification in cataract patients was slightly better than small incision cataract extracapsular extraction in correcting astigmatism,improving visual acuity,and regulating macular thickness.However,due to the high energy of ultrasonic emulsification,the risk of complications such as high postoperative intraocular pressure was higher.Small-incision extracapsular cataract extraction has better application value in economically disadvantaged areas. 展开更多
关键词 cataract cataract ultrasonic emulsification Small incision cataract extracapsular extraction Therapeutic efficacy
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Efficacy of combined cataract extraction and endoscopic cyclophotocoagulation for the reduction of intraocular pressure and medication burden 被引量:12
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作者 Sammie J.Roberts Matthew Mulvahill +3 位作者 Jeffrey R.SooHoo Mina B.Pantcheva Malik Y.Kahook Leonard K.Seibold 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2016年第5期693-698,共6页
AIM: To report on the efficacy of combined endoscopic cyclophotocoagulation(ECP) and phacoemulsification cataract extraction(PCE) with intraocular lens placement for reduction of intraocular pressure(IOP) and m... AIM: To report on the efficacy of combined endoscopic cyclophotocoagulation(ECP) and phacoemulsification cataract extraction(PCE) with intraocular lens placement for reduction of intraocular pressure(IOP) and medication burden in glaucoma.·METHODS: A retrospective case review of 91 eyes(73patients) with glaucoma and cataract that underwent combined PCE/ECP surgery was performed. Baseline demographic and ocular characteristics were recorded,as well as intraocular pressure, number of glaucoma medications, and visual acuity postoperatively with 12-month follow-up. Treatment failure was defined as less than 20% reduction in IOP from baseline on two consecutive visits(at 1, 3, 6, or 12 mo postoperatively),IOP ≥21 mm Hg or ≤5 mm Hg on two consecutive visits, or additional glaucoma surgery performed within12 mo after PCE/ECP.·RESULTS: Overall, mean medicated IOP was reduced from 16.65 mm Hg at baseline to 13.38 mm Hg at 12mo(P 0.0001). Mean number of glaucoma medications was reduced from 1.88 medications at baseline to 1.48 medications at 12mo(P =0.0003). At 3mo postoperatively,the success rate was 73.6%(95%CI: 63.3, 81.5), 57.1% at6mo(95% CI: 46.3, 66.6), and 49.7% at 12mo(95% CI:38.9, 59.6). Patient demographic characteristics were not associated with treatment success. The only ocular characteristic associated with treatment success was a higher baseline IOP.· CONCLUSION: Combined PCE/ECP surgery is an effective surgical option for the reduction of IOP and medication burden in glaucoma patients. Patients withhigher baseline IOP levels are most likely to benefit from this procedure. 展开更多
关键词 endoscopic cyclophotocoagulation GLAUCOMA cataract extraction
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Inhibitory Effect of Short-Term Palpebral Margin Cleaning with Antibiotic Eye Drops on Ocular Surface Flora before Cataract Extraction:A New Preoperative Antibacterial Method 被引量:3
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作者 Xiaoyong Chen Hongyuan Cai +1 位作者 Yinan Liu Jing Hong 《Chinese Medical Sciences Journal》 CAS CSCD 2022年第2期118-126,共9页
Objective To explore the clinical significance of the combined application of palpebral margin cleaning and antibiotic eye drops in inhibiting bacterial growth in the palpebral margin and conjunctival sacs before cata... Objective To explore the clinical significance of the combined application of palpebral margin cleaning and antibiotic eye drops in inhibiting bacterial growth in the palpebral margin and conjunctival sacs before cataract extraction.Methods In this study,61 patients(97 eyes)with age-related cataract who underwent phacoemulsification and intraocular lens implantation were selected,and randomly grouped.In the experimental group,the combined application of palpebral margin cleaning with cotton pads and levofloxacin eye drops was given for three days before the surgery.In the control group,levofloxacin eye drops alone were applied for three consecutive days.Bacteria samples from the conjunctival sac and eyelid margins were cultivated and identified before and three days after taking antimicrobial measures,respectively.Results In the experimental group,the positive rates of the two bacteria samples were 100%(50/50)and 40%(20/50)before and 10%(5/50)and 0%(0/50)after the treatment.In the control group,the positive rates of the two bacteria samples were 97.9%(46/47)and 29.8%(14/47)before and 40.4%(19/47)and 10.6%(5/47)after the treatment.The positive rates between the two groups were not significantly different before taking antimicrobial measures(P=0.485 and 0.395),while they were significantly different after taking antimicrobial measures(P=0.001 and 0.024).Conclusion Combined application of eyelid and palpebral margin cleaning with cotton pads and antibiotic eye drops before cataract extraction imparted excellent antibacterial effects. 展开更多
关键词 antibiotic prophylaxis cataract extraction eyelid cleaning MICROBIOTA
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Liquefaction for cataract extraction 被引量:1
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作者 Georgios Labiris Aspasia Toli +3 位作者 Damaskini Polychroni Maria Gkika Dimitrios Angelonias Vassilios P.Kozobolis 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2016年第2期306-311,共6页
A systematic review of the recent literature regarding the implementation of the liquefaction in cataract surgery and its short-term and long-term outcomes in various parameters that affect the quality of patients" l... A systematic review of the recent literature regarding the implementation of the liquefaction in cataract surgery and its short-term and long-term outcomes in various parameters that affect the quality of patients" life, including visual rehabilitation and possible complications was performed based on the PubMed, Medline, Nature and the American Academy of Ophthalmology databases in November 2013 and data from 14 comparative studies were included in this narrative review. Liquefaction is an innovative technology for cataract extraction that uses micropulses of balanced salt solution to liquefy the lens nucleus. Most studies reported that liquefaction is a reliable technology for mild to moderate cataracts, while fragmentation difficulties may be encountered with harder nuclei. 展开更多
关键词 Aqualase LIQUEFACTION cataract extraction ENDOTHELIUM corneal thermal injury
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Graft survival and visual outcome after simultaneous penetrating keratoplasty and cataract extraction 被引量:1
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作者 Mansour M. Al-Mohaimeed 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2013年第3期385-389,共5页
AIM: To evaluate the indications, complications, and visual and graft survival outcomes in eyes that had undergone simultaneous cataract extraction and penetrating keratoplasty (PKP). ·METHODS: We described a ret... AIM: To evaluate the indications, complications, and visual and graft survival outcomes in eyes that had undergone simultaneous cataract extraction and penetrating keratoplasty (PKP). ·METHODS: We described a retrospective study of 101 patients who had undergone simultaneous cataract extraction and PKP at King Khaled Eye Specialist Hospital between January 1, 2001, and December 31, 2002. All patients were followed up postoperatively with maximum follow-up 68 months. ·RESULTS: The mean age of patients was 61 years. The mean overall follow -up was 27 months. The most common indications for surgery were corneal scarring (45.5% ), previous failed graft (15.8% ), corneal ulcer (12.9% ), Fuchs endothelial dystrophy (8.9% ), stromal dystrophy (2.9% ), and other conditions (14.5% ). Overall, 69 grafts (68.3% ) remained clear at final follow -up. Previous glaucoma or postoperative glaucoma had no statistically significant effects on graft outcome (P 】0.05). The graft rejection rate (17.8% ) was a significant risk factor for failure (P =0.00). Age, gender, indications for surgery, corneal graft diameter, and intraoperative vitreous loss had no statistically significant effects on the PKP outcome (P 】0.05). Postoperative visual acuity was significantly associated with preoperative visual acuity (P 【0.01). ·CONCLUSION: The present study provides evidence that performing a combined procedure results in more rapid visual rehabilitation and good graft clarity. 展开更多
关键词 penetrating keratoplasty cataract extraction graft failure
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More than 10 Years of Experience with Immediate Sequential Bilateral Cataract Extraction (ISBCE)--A Retrospective Study 被引量:1
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作者 Ivo Guber Ciara Bergin Jorg Stürmer 《Open Journal of Ophthalmology》 2014年第4期139-144,共6页
Background: To evaluate the safety of immediate sequential bilateral cataract extraction (ISBCE) with respect to indications, visual outcomes, complications, benefits and disadvantages. Methods: This is a retrospectiv... Background: To evaluate the safety of immediate sequential bilateral cataract extraction (ISBCE) with respect to indications, visual outcomes, complications, benefits and disadvantages. Methods: This is a retrospective review of all ISBCEs performed at Kantonsspital Winterthur, Switzerland, between April 2000 and September 2013. The case notes of 500 eyes of 250 patients were reviewed. Of these 500 eyes, 472 (94.4%) had a straight forward phacoemulsification with posterior chamber intraocular lens implantation;21 (4.2%) had a planned extracapsular cataract extraction;4 (0.8%) had an intracapsular cataract extraction and 3 (0.6%) had a combined phacoemulsification with trabeculectomy. Results: Over 66% of eyes achieved improved visual acuity (at least 3 Snellen lines) following ISBCE. Median preoperative best corrected visual acuity (BCVA) was 0.5 LogMAR;the interquartile range was [0.4, 1] LogMAR. At one week control the median BCVA was 0.3 LogMAR, IQR [0.1, 0.5] LogMAR. At one month the median BCVA was 0.15 LogMAR, IQR [0.05, 0.3] (p < 0.01). There were no sight-threatening intraoperative or postoperative complications observed. Conclusions: ISBCE is an effective and safe option with high degree of patient satisfaction. The relative benefits of ISBCE should be balanced against the theoretically enhanced risks. 展开更多
关键词 cataract cataract Surgery Immediate Sequential Bilateral cataract extraction
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A Clinical Analysis of 120 Cases with Traumatic Cataract Treated by Extracapsular Cataract Extraction and Posterior Chamber Intraocular Lens Implantation
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作者 汤崇凯 马赛芬 《The Journal of Biomedical Research》 CAS 1998年第1期44-46,共3页
Extracapsular cataract extraction was performed combined with posterior chamber intraocular lens implantation on 120 inpatients (122 eyes) with traumatic cataract from 1992 to 1997. The results revealed that this comb... Extracapsular cataract extraction was performed combined with posterior chamber intraocular lens implantation on 120 inpatients (122 eyes) with traumatic cataract from 1992 to 1997. The results revealed that this combined operation can make most of them get useful visual acuity, although they were often accompanied with several comlicated eye injuries. We think the most important thing is to choose suitable opertion time, the reasonable operation method and take close followup after operation. 展开更多
关键词 traumatic cataract extracapsular cataract extraction (ECCE) posterior chamber intraocular lens(PCIOL) implantation combined operation
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Self-management of cataract extraction among diabetes patients
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作者 Funke Elizabeth AKINTUNDE Olaolorunpo OLORUNFEMI +4 位作者 Rasidi Akinade SALAWU Mary Olabisi OYEKANMI Babatunde Abdul-latef ADEYENI Olawale Rasheed OLADAPO Jeminat Omotade SODIMU 《Journal of Integrative Nursing》 2021年第4期170-175,共6页
Background:Diabetes-related cataract extraction is a minor surgery required to regain full vision.One of the recognized factors that can delay or prevent full-vision recovery is poor management,and most of this manage... Background:Diabetes-related cataract extraction is a minor surgery required to regain full vision.One of the recognized factors that can delay or prevent full-vision recovery is poor management,and most of this management is being carried out by patients themselves.Objective:This study aimed to assess the knowledge of diabetes patients on self-management after cataract extraction in two tertiary hospitals in Osun State.Methods:A cross-sectional descriptive design was conducted among 97 diabetes patients who underwent cataract extraction and were attending clinics and follow-up visits in Osun State.A self-structured questionnaire was used for data collection.Results:Moderate knowledge was found among the participants on an appropriate diet(56.7%),prevention of injury risk(57.5%),prevention of infection risk(50.9%),and low knowledge on the technique of administration of eye drop(60.8%)after cataract extraction,whereas 74.7%of the total respondents were knowledgeable on the indication for follow-up visit after cataract extraction,these results were found to be below the expected knowledge level.Conclusion:An intensive and comprehensive educational initiative by nurses should be tailored to meet the specific needs of diabetes patients with cataract surgery.Nurses also need to implement the use of checklist which will enhance learning and improve patient understanding of self-management after cataract extraction. 展开更多
关键词 cataract extraction diabetes patient SELF-MANAGEMENT NIGERIA postoperative cataract care
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Inhibitory Effects of Grape Seed Proanthocyanidin Extract on Selenite-induced Cataract Formation and Possible Mechanism 被引量:14
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作者 张璇 胡义珍 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2012年第4期613-619,共7页
This study investigated the inhibitory effect of grape seed proanthocyanidin extract(GSPE) on selenite-induced cataract formation in rats and the possible mechanism.Eighty 8-day-old Sprague-Dawley rats were divided ra... This study investigated the inhibitory effect of grape seed proanthocyanidin extract(GSPE) on selenite-induced cataract formation in rats and the possible mechanism.Eighty 8-day-old Sprague-Dawley rats were divided randomly into 5 groups:control group,model group,three GSPE groups(low dose,medium dose and high dose).Control group received subcutaneous injection of physiological saline.Model group was given subcutaneous injection of sodium selenite(20 μmol/kg body weight) on the postpartum day 10,and once every other day for consecutive three times thereafter.GSPE treated groups were respectively administered GSPE at doses of 50,100,and 200 mg/kg body weight intragastrically 2 days prior to the selenite injection(that was,on the postpartum day 8),and once daily for fourteen consecutive days thereafter.The opacity of lenses was observed,graded and photographed under the slit lamp microscopy and the maximal diameter of the nuclear cataract plaques was measured.The lenses were analyzed for superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GSH-PX),malondialdehyde(MDA),calcium(Ca 2+),nitric oxide(NO) and anti-hydroxyl radical ability(anti-OH).The histomorphology of lenses was observed with HE staining under a light microscope.The levels of calpainⅡ,and iNOS protein and mRNA expression in lenses were detected by using immunohistochemistry and real-time quantitative RT-PCR.The results showed subcutaneous injection of sodium selenite led to severe nuclear cataract in model group,and the achievement ratio of model group was 100%.As compared with model group,the degree of lenses opacity and the maximal diameter of nuclear cataract plaques were significantly reduced in GSPE-treated groups.Moreover,we observed selenite treatment caused a significant decrease in the activities of antioxidative enzymes(SOD,CAT,GSH-PX) and anti-OH ability,accompanied by a significant increase in the levels of MDA,NO,Ca 2+ as well as iNOS,and calpainⅡ protein and mRNA expression.Administration of GSPE could dose-dependently preserve the activities of these antioxidative enzymes and anti-OH ability,accompanied by a significant reduction in the levels of MDA,NO,Ca 2+ as well as iNOS,and calpainⅡ protein and mRNA expression.These results suggested that GSPE markedly prevented selenite-induced cataract formation probably by suppressing the generation of lipid peroxidation and free radicals as well as the activation of iNOS,and calpainⅡ in the lenses. 展开更多
关键词 grape seed proanthocyanidin extract selenite-induced cataract oxidative stress INOS calpainⅡ
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激光辅助巩膜切除及白内障摘除联合房角分离治疗闭角型青光眼
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作者 谢九冰 陈喜月 +3 位作者 岳向东 陈艳辉 姜伟 杨杉杉 《实用医学杂志》 CAS 北大核心 2024年第2期213-218,共6页
目的探究激光辅助巩膜切除及白内障摘除联合房角分离治疗闭角型青光眼的临床疗效。方法选择闭角型青光眼患者162例为研究对象,分为观察组81例行激光辅助巩膜切除及白内障摘除联合房角分离术,对照组81例行白内障摘除联合房角分离术,观察... 目的探究激光辅助巩膜切除及白内障摘除联合房角分离治疗闭角型青光眼的临床疗效。方法选择闭角型青光眼患者162例为研究对象,分为观察组81例行激光辅助巩膜切除及白内障摘除联合房角分离术,对照组81例行白内障摘除联合房角分离术,观察两组患者治疗效果。结果观察组患者术后视力、BCVA、房角宽度、角膜内皮细胞计数高于对照组,眼压、中央前房深度、角膜厚度均低于对照组,观察组不良反应发生率(6.2%)低于对照组(13.6%)。术后随访,两组眼压均无再升高,对照组滤过泡高度降低无观察组明显;术后1个月观察组BCVA、角膜内皮细胞计数高于对照组(P<0.05),角膜厚度低于对照组(P<0.05),术后3个月、6个月差异均无统计学意义;散光情况术后3个月观察组优于对照组,术后1个月、6个月差异无统计学意义(P>0.05)。结论激光辅助巩膜切除及白内障摘除联合房角分离术治疗闭角型青光眼临床效果好,安全性高。 展开更多
关键词 激光辅助巩膜切除 白内障摘除 房角分离 闭角型青光眼
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小儿白内障摘除术后青光眼nomogram预测模型建立和效能评价
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作者 史萌萌 陈高腾 孙广莉 《河南医学研究》 CAS 2024年第18期3317-3321,共5页
目的建立小儿白内障摘除术后青光眼的nomogram预测模型,并评价其预测效能。方法回顾性分析2019年1月至2023年9月郑州大学第一附属医院收治的352例624眼小儿白内障摘除术患儿的临床资料,根据术后青光眼发生情况分为青光眼组、无青光眼组... 目的建立小儿白内障摘除术后青光眼的nomogram预测模型,并评价其预测效能。方法回顾性分析2019年1月至2023年9月郑州大学第一附属医院收治的352例624眼小儿白内障摘除术患儿的临床资料,根据术后青光眼发生情况分为青光眼组、无青光眼组。术后随访6个月~4.5 a,详细记录患儿术后青光眼发生情况,单因素、多因素logistic回归分析小儿白内障摘除术后发生青光眼的影响因素,基于多因素分析结果构建术后青光眼的nomogram预测模型,采用受试者工作特征(ROC)曲线分析该模型预测价值,并对该模型预测效能进行评价与验证。结果352例患儿术后6个月~4.5 a共发生46例术后青光眼,发生率为13.07%;青光眼患儿手术年龄[(5.82±1.90)个月]早于无青光眼组[(7.82±2.56)个月],核性白内障、伴其他眼部先天异常、先天性白内障家族史、角膜直径≤10 mm、眼内手术次数>1次、术后1个月中央角膜厚度(CCT)增加、术后瞳孔缘虹膜后粘连患儿占比高于无青光眼组,差异有统计学意义(P<0.05);logistic分析显示,手术年龄、核性白内障、伴其他眼部先天异常、先天性白内障家族史、角膜直径≤10 mm、术后1个月CCT增加、术后瞳孔缘虹膜后粘连是术后青光眼的独立影响因素(P<0.05);构建nomogram模型,其C-index为0.817,ROC曲线显示该模型预测术后青光眼的曲线下面积(AUC)为0.817,校准曲线、临床影响曲线评价显示,该模型具有良好应用价值及临床正向净收益。结论手术年龄、核性白内障、伴其他眼部先天异常、先天性白内障家族史、角膜直径≤10 mm、术后1个月CCT增加、术后瞳孔缘虹膜后粘连是小儿白内障摘除术后继发青光眼的独立影响因素,根据上述因素构建nomogram模型对术后青光眼具有一定预测价值,并具有良好区分度、校准度、实用度,可作为临床预测术后青光眼的有效模型,并对临床防治具有一定指导价值。 展开更多
关键词 先天性白内障 白内障摘除术 继发性青光眼 风险因素 nomogram模型 预测
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老年性白内障患者日间手术模式的构建与临床效果分析
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作者 项彩萍 李爱华 +1 位作者 燕玲 季青山 《中国临床保健杂志》 CAS 2024年第1期116-119,共4页
目的探讨80岁及以上老年白内障患者日间手术模式的构建与应用效果。方法回顾性分析2021年1—7月中国科学技术大学附属第一医院(安徽省立医院)收治的80岁及以上182例老年白内障患者资料,这些患者由同一位高年资医生手术,将普通眼科病房住... 目的探讨80岁及以上老年白内障患者日间手术模式的构建与应用效果。方法回顾性分析2021年1—7月中国科学技术大学附属第一医院(安徽省立医院)收治的80岁及以上182例老年白内障患者资料,这些患者由同一位高年资医生手术,将普通眼科病房住院91例患者作为对照组,日间眼科病房的91例患者作为观察组,比较2组对围术期相关知识的掌握程度、术后并发症发生率、住院费用,患者满意度。结果研究组患者对围术期相关知识的掌握程度及满意度均优于对照组,差异有统计学意义(P<0.05);2组术后并发症发生率比较,差异无统计学意义(P>0.05),且2组患者均无24 h非计划再手术。结论老年性白内障患者日间手术模式可有效降低平均住院日,减少住院费用,提高医患双方满意度,且不增加术后并发症。 展开更多
关键词 白内障摘除术 围手术期医护 病人满意度 手术后并发症 老年人
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小牛血去蛋白提取物眼用凝胶在老年性硬核性白内障小切口摘除手术中的应用效果
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作者 邢影 袁军 赵笑雨 《四川生理科学杂志》 2024年第1期203-205,共3页
目的:研究小牛血去蛋白提取物眼用凝胶在老年性硬核性白内障小切口摘除手术中的应用效果。方法:选取我院2021年6月至2022年12月诊治的老年性硬核性白内障患者152例(152眼)作为研究对象。随机将患者分为对照组和观察组,各76例。对照组采... 目的:研究小牛血去蛋白提取物眼用凝胶在老年性硬核性白内障小切口摘除手术中的应用效果。方法:选取我院2021年6月至2022年12月诊治的老年性硬核性白内障患者152例(152眼)作为研究对象。随机将患者分为对照组和观察组,各76例。对照组采取小切口摘除术,观察组在对照组基础上加用小牛血去蛋白提取物眼用凝胶治疗。分析对比两组术前及术后1、8 w的视力、前房炎性反应、角膜内皮细胞相关参数,其中视力采用标准视力量表测定,角膜内皮细胞相关参数采用SP-1P非接触型的角膜内皮细胞仪测量。结果:观察组术后1 w、8 w的矫正视力均较对照组显著提高(P<0.05);术后1 w前房炎性反应较对照组减轻(P<0.05)。两组术后1 w中央角膜厚度高于术前,而六边形细胞的比例、角膜内皮细胞的密度均显著低于术前;术后8 w中央角膜厚度显著低于术后1 w,六边形细胞的比例、角膜内皮细胞的密度均显著高于术后1 w;且观察组患者的术后1 w中央角膜厚度显著低于对照组,而六边形细胞的比例、角膜内皮细胞的密度显著高于对照组(P<0.05)。结论:小牛血去蛋白提取物眼用凝胶在老年性硬核性白内障小切口摘除手术中,能改善角膜内皮细胞相关参数。 展开更多
关键词 硬核性白内障 小切口摘除术 小牛血清去蛋白眼用凝胶 前房炎症反应
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超声乳化白内障摘出联合囊袋张力环植入术治疗高度近视伴白内障的效果及对人工晶体稳定性、视力状态的影响
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作者 沈颖 魏海英 《临床医学研究与实践》 2024年第17期104-108,共5页
目的分析超声乳化白内障摘出联合囊袋张力环植入术治疗高度近视伴白内障的效果。方法选择2019年2月至2022年3月收治的90例高度近视伴白内障患者为研究对象,以随机数字表法将其分为对照组和观察组,各45例。对照组接受超声乳化白内障摘出... 目的分析超声乳化白内障摘出联合囊袋张力环植入术治疗高度近视伴白内障的效果。方法选择2019年2月至2022年3月收治的90例高度近视伴白内障患者为研究对象,以随机数字表法将其分为对照组和观察组,各45例。对照组接受超声乳化白内障摘出治疗,观察组在对照组基础上加施囊袋张力环植入术治疗。比较两组的治疗效果。结果术后6个月,观察组的最佳矫正视力(BCVA)、角膜内皮细胞密度、六边形细胞百分率高于对照组,中央角膜厚度小于对照组(P<0.05)。术后3、6个月,观察组的晶体偏心量、倾斜角小于对照组(P<0.05)。术后6个月,观察组的三叶草像差、总高阶像差、球差、彗差优于对照组(P<0.05)。观察组的术后并发症总发生率低于对照组(P<0.05)。结论超声乳化白内障摘出联合囊袋张力环植入术治疗高度近视伴白内障可提高人工晶体稳定性,改善角膜质量,还能降低术后并发症发生风险,促进视力恢复,值得推广。 展开更多
关键词 超声乳化白内障摘出 囊袋张力环植入术 高度近视 白内障 视力状态
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Phaco drill与小切口非超声乳化白内障摘除术治疗硬核白内障患者的效果
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作者 汪军红 屈晶 《中外医学研究》 2024年第2期49-52,共4页
目的:探讨Phaco drill与小切口非超声乳化白内障摘除术治疗硬核白内障患者的效果。方法:回顾性选取2020年10月—2022年4月麻城市中医医院收治的60例硬核白内障患者。根据不同手术治疗方法将其分为Phaco组(n=25)和小切口组(n=35)。小切... 目的:探讨Phaco drill与小切口非超声乳化白内障摘除术治疗硬核白内障患者的效果。方法:回顾性选取2020年10月—2022年4月麻城市中医医院收治的60例硬核白内障患者。根据不同手术治疗方法将其分为Phaco组(n=25)和小切口组(n=35)。小切口组给予小切口非超声乳化白内障摘除术,Phaco组给予Phaco drill。比较两组术前、术后1个月眼睛恢复情况,术前,术后3 d、术后1个月及术后3个月角膜散光度,并发症。结果:术后1个月,Phaco组最佳矫正视力(best corrected visual acuity,BCVA)、眼压(intraocular pressure,IOP)、角膜内皮细胞(corneal endothelial cell,CEC)密度均高于小切口组,差异有统计学意义(P<0.05),两组中央角膜厚度(central corneal thickness,CCT)比较,差异无统计学意义(P>0.05)。重复测量方差分析显示,角膜散光度组间、时间、交互比较,差异有统计学意义(P<0.001)。术后3 d、术后1个月,Phaco组角膜散光度均低于小切口组,差异有统计学意义(P<0.05)。Phaco组术后并发症发生率低于小切口组,差异有统计学意义(P<0.05)。结论:Phaco drill治疗硬核白内障可促进患者恢复,近期对角膜散光度的影响较小,对角膜内皮损伤较小,且术后并发症发生率低。 展开更多
关键词 Phaco drill 小切口非超声乳化白内障摘除术 硬核白内障 最佳矫正视力 角膜散光度 并发症
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小切口白内障囊外摘除术与超声乳化术治疗硬核白内障患者的效果比较
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作者 陶平 《中国民康医学》 2024年第2期153-155,共3页
目的:比较小切口白内障囊外摘除术与超声乳化术治疗硬核白内障患者的效果。方法:回顾性分析2022年10月至2023年10月该院收治的90例硬核白内障患者的临床资料,按照手术方式不同将其分为对照组和观察组各45例。对照组采用超声乳化术治疗,... 目的:比较小切口白内障囊外摘除术与超声乳化术治疗硬核白内障患者的效果。方法:回顾性分析2022年10月至2023年10月该院收治的90例硬核白内障患者的临床资料,按照手术方式不同将其分为对照组和观察组各45例。对照组采用超声乳化术治疗,观察组采用小切口白内障囊外摘除术治疗。比较两组手术前后泪膜功能[泪膜破裂时间(BUT)、泪液分泌试验(STT)]、角膜功能[角膜厚度、角膜荧光染色(FL)评分]、视力水平及并发症发生率。结果:术后3 d,两组BUT、STT值及角膜厚度均小于术前,但观察组大于对照组,两组FL评分均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);术后3个月,两组患眼视力水平均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组术后并发症发生率为8.89%(4/45),低于对照组的35.56%(16/45),差异有统计学意义(P<0.05)。结论:小切口白内障囊外摘除术治疗硬核白内障患者效果良好,可提高患者视力水平,减少对泪膜、角膜功能的损伤,降低术后并发症发生率,效果和安全性优于超声乳化术。 展开更多
关键词 小切口 白内障囊外摘除术 超声乳化术 硬核白内障 泪膜功能 角膜功能
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两种术式联合治疗白内障合并青光眼的疗效分析
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作者 陆诗林 刘振豹 《系统医学》 2024年第6期51-54,共4页
目的探究白内障合并青光眼运用两种术式的有效性。方法选取聊城市第三人民医院于2021年2月—2023年2月收治的100例白内障合并青光眼患者为研究对象,利用随机数表法分为参照组(50例,白内障超声乳化人工晶体植入手术治疗)和研究组(50例,... 目的探究白内障合并青光眼运用两种术式的有效性。方法选取聊城市第三人民医院于2021年2月—2023年2月收治的100例白内障合并青光眼患者为研究对象,利用随机数表法分为参照组(50例,白内障超声乳化人工晶体植入手术治疗)和研究组(50例,改良小切口非超声乳化白内障摘除人工晶状体植入与小梁切除术联合治疗),比较两组患者的眼压、视力水平及前房深度。结果术后,研究组的眼压小于参照组,视力水平优于参照组,前房深度大于参照组,差异有统计学意义(P均<0.05)。研究组术后并发症总发生率(4.00%)低于参照组(16.00%),差异有统计学意义(χ^(2)=4.000,P=0.045)。结论白内障合并青光眼运用改良小切口非超声乳化白内障摘除人工晶状体植入与小梁切除术联合治疗的效果突出,可以更好地降低术后的眼压,提高视力水平和前房深度,降低并发症发生率。 展开更多
关键词 青光眼 改良小切口非超声乳化白内障摘除术 白内障 小梁切除手术 眼压 前房深度
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对比超声乳化术与小切口囊外摘除术治疗白内障的效果
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作者 李华萍 《临床研究》 2024年第1期53-56,共4页
目的分析超声乳化术与小切口囊外摘除术治疗白内障的效果差异。方法回顾性分析商丘市眼科医院2018年1月至2022年12月接受治疗的白内障患者189人(189眼)的数据实施。依据患者所接受的手术方法差异实施分组,分为A组(接受超声乳化手术,n=93... 目的分析超声乳化术与小切口囊外摘除术治疗白内障的效果差异。方法回顾性分析商丘市眼科医院2018年1月至2022年12月接受治疗的白内障患者189人(189眼)的数据实施。依据患者所接受的手术方法差异实施分组,分为A组(接受超声乳化手术,n=93)以及B组(接受小切口囊外摘除手术,n=96)。均选择术前(T_(1))、术后7 d(T_(2))、术后1个月(T_(3))、术后3个月(T_(4))共4个时间点的数据实施分析,对比两组患者治疗效果。对比两组患者不同时间点的视力情况、角膜内皮细胞数量、黄斑区厚度以及T_(4)时两组患者的黄斑水肿发生率,不同时间点手术源性角膜散光值,两组患者术后3个月内的并发症情况。结果T_(1)、T_(3)、T_(4)时间点,两组患者的裸眼视力、最佳矫正视力数据差异无统计学意义(P>0.05),T_(2)时间点,小切口囊外摘除手术组的裸眼视力、最佳矫正视力水平均优于于超声乳化术组,差异有统计学意义(P<0.05)。T_(1)时间点,两组患者的角膜内皮细胞数量数据差异无统计学意义(P>0.05),在T_(2)、T_(3)、T_(4)时间点,B组的角膜内皮细胞数量均高于A组,差异有统计学意义(P<0.05)。T_(1)、T_(4)时间点,两组患者的黄斑区厚度和T_(4)时两组患者的黄斑水肿发生率的数据差异无统计学意义(P>0.05),在T_(2)、T_(3)时间点,B组的黄斑区厚度均低于A组,差异有统计学意义(P<0.05)。两组患者不同时间点的手术源性角膜散光值数据差异无统计学意义(P>0.05)。B组术后3个月的并发症发生率低于A组,差异有统计学意义(P<0.05)。结论针对白内障的患者,超声乳化术和小切口囊外摘除术均为有效的手术方法,两种方法相比,小切口囊外摘除术更利于患者术后短期的恢复以及围手术期并发症的降低。 展开更多
关键词 超声乳化 小切口囊外摘除 白内障 晶状体 矫正视力
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飞秒激光LenSAR与LenSx联合白内障囊外摘除术在老年白内障患者治疗中的效果比较
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作者 魏小威 《中国医学工程》 2024年第6期75-78,共4页
目的比较飞秒激光LenSAR与LenSx联合白内障囊外摘除术在老年白内障患者治疗中的效果,以期为临床完善治疗方式提供依据。方法前瞻性选取永煤集团总医院2021年4月至2023年3月期间收治的老年白内障患者96例作为研究对象,依据随机抽签法分成... 目的比较飞秒激光LenSAR与LenSx联合白内障囊外摘除术在老年白内障患者治疗中的效果,以期为临床完善治疗方式提供依据。方法前瞻性选取永煤集团总医院2021年4月至2023年3月期间收治的老年白内障患者96例作为研究对象,依据随机抽签法分成SAR组与Sx组,每组48例。两组均行白内障囊外摘除术,其中SAR组行飞秒激光LenSAR治疗,Sx组行飞秒激光LenSx治疗,统计对比两组围术期指标、手术前后眼压、并发症发生率。结果SAR组前囊膜切开时间、尝试对接次数、预劈核时间以及激光发射时间均少于Sx组,负压吸引眼球时间长于Sx组(P<0.05);术后两组眼压较术前均升高,且SAR组眼压升高幅度高于Sx组(P<0.05);与Sx组27.08%相比,SAR组并发症发生率(8.33%)下降(P<0.05)。结论飞秒激光LenSAR与LenSx联合白内障囊外摘除术在老年白内障患者治疗中的效果各异,其中LenSAR便于接口对接,且并发症少,而LenSx能有效控制眼压且减少总负压吸引眼球时长。 展开更多
关键词 飞秒激光 LenSAR LenSx 白内障囊外摘除术 老年 白内障
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