The Nature of Inertia Explained Using the Field Theory

Analysis of free fall and acceleration of the mass on the Earth shows that using abstract entities such as absolute space or inertial space to explain mass dynamics leads to the violation of the principle of action and reaction. Many scientists including Newton, Mach, and Einstein recognized that inertial force has no reaction that originates on mass. Einstein calls the lack of reaction to the inertial force a serious criticism of the space-time continuum concept. Presented is the hypothesis that the inertial force develops in an interaction of two masses via the force field. The inertial force created by such a field has reaction force. The dynamic gravitational field predicted is strong enough to be detected in the laboratory. This article describes the laboratory experiment which can prove or disprove the hypothesis of the dynamic gravitational field. The inertial force, calculated using the equation for the dynamic gravitational field, agrees with the behavior of inertial force observed in the experiments on the Earth. The movement of the planets in our solar system calculated using that equation is the same as that calculated using Newton’s method. The space properties calculated by the candidate equation explain the aberration of light and the results of light propagation experiments. The dynamic gravitational field can explain the discrepancy between the observed velocity of stars in the galaxy and those predicted by Newton’s theory of gravitation without the need for the dark matter hypothesis.

Noether symmetry and conserved quantity for dynamical system with non-standard Lagrangians on time scales

This paper focuses on studying the Noether symmetry and the conserved quantity with non-standard Lagrangians, namely exponential Lagrangians and power-law Lagrangians on time scales. Firstly, for each case, the Hamilton prin- ciple based on the action with non-standard Lagrangians on time scales is established, with which the corresponding Euler-Lagrange equation is given. Secondly, according to the invariance of the Hamilton action under the infinitesimal transformation, the Noether theorem for the dynamical system with non-standard Lagrangians on time scales is established. The proof of the theorem consists of two steps. First, it is proved under the infinitesimal transformations of a special one-parameter group without transforming time. Second, utilizing the technique of time-re-parameterization, the Noether theorem in a general form is obtained. The Noether-type conserved quantities with non-standard Lagrangians in both clas- sical and discrete cases are given. Finally, an example in Friedmann-Robertson-Walker spacetime and an example about second order Duffing equation are given to illustrate the application of the results.

A Project Management and Decision Support System for Non-standard Equipment's Eexecuting Work

Based on the features of the non-standard equipment executing work, a project management and decision support system oriented to the non-standard equipment is developed, and the information model, function model as well as the structure framework of the system are also introduced in this paper.

Canonical Transformations and Poisson Theory for Dynamics with Non-Standard Lagrangians

The canonical transformation and Poisson theory of dynamical systems with exponential,power-law,and logarithmic non-standard Lagrangians are studied,respectively.The criterion equations of canonical transformation are established,and four basic forms of canonical transformations are given.The dynamic equations with non-standard Lagrangians admit Lie algebraic structure.From this,we es-tablish the Poisson theory,which makes it possible to find new conservation laws through known conserved quantities.Some examples are put forward to demonstrate the use of the theory and verify its effectiveness.

Orthotopic liver transplantation for giant liver haemangioma: A case report

In liver haemangiomas, the risk of complication rises with increasing size, and treatment can be obligatory. Here we present a case of a 46-year-old female who suffered from a giant haemangioma causing severe portal hypertension and vena cava compression, leading to therapy refractory ascites, hyponatremia and venostasis-associated thrombosis with pulmonary embolism. The patients did not experience tumour rupture or consumptive coagulopathy. Surgical resection was impossible because of steatosis of the non-affected liver. Orthotopic liver transplantation was identified as the only treatment option. The patient's renal function remained stable even though progressive morbidity and organ allocation were improbable according to the patient's lab model for end-stage liver disease(lab MELD) score. Therefore, non-standard exception status was approved by the European organ allocation network "Eurotransplant". The patient underwent successful orthotopic liver transplantation 16 mo after admission to our centre. Our case report indicates the underrepresentation of morbidity associated with refractory ascites in the lab MELD-based transplant allocation system, and it indicates the necessity of promptly applying for non-standard exception status to enable transplantation in patients with a severe clinical condition but low lab MELD score. Our case highlights the fact that liver transplantation should be considered early in patients with non-resectable, symptomatic benign liver tumours.

Improved theory of generalized meteo-ballistic weighting factor functions and their use

It follows from the analysis of artillery fire errors that approximately two-thirds of the inaccuracy of indirect artillery fire is caused by inaccuracies in the determination of the meteo parameters included in fire error budget model.Trajectories calculated under non-standard conditions are considered to be perturbed.The tools utilized for the analysis of perturbed trajectories are weighting factor functions(WFFs)which are a special kind of sensitivity functions.WFFs are used for calculation of meteo ballistic elements B(ballistic wind w B,densityρB,virtual temperatureτB,pressure p B)as well.We have found that the existing theory of WFF calculation has several significant shortcomings.The aim of the article is to present a new,improved theory of generalized WFFs that eliminates the deficiencies found.Using this theory will improve methods for designing firing tables,fire control systems algorithms,and meteo message generation algorithms.

Functional annotation and enrichment analysis of differentially expressed serum proteins in patients with type 2 diabetes after dapagliflozin

BACKGROUND Only 50% of patients with type 2 diabetes mellitus(T2DM) can control their blood glucose levels. Dapagliflozin is a selective inhibitor of sodium-glucose cotransporter 2(SGLT-2) that improves the insulin sensitivity of the liver and peripheral tissues. Many studies confirmed that SGLT2 inhibitors reduce blood glucose and have multiple beneficial effects such as weight loss, lipid regulation, and kidney protection. Nevertheless, the mechanisms of the renal and cardiovascular protective effects of dapagliflozin from the perspective of differentially expressed proteins in the serum of T2DM patients have not been intensively explored so far.AIM To identify differentially expressed proteins associated with dapagliflozin treatment in patients with T2DM.METHODS Twenty T2DM patients [hemoglobin A1c(HbA1c) 7.0%-10.0%] were enrolled at The Affiliated Hospital of Inner Mongolia Medical University between January 1, 2017 and December 1, 2018. They received dapagliflozin(10 mg/d) for 3 mo, and the HbA1c < 7.0% target was achieved. The changes in clinical indexes were compared before and after treatments. Label-free quantitative proteomics was used to identify differentially expressed proteins using the serum samples of five patients. The identified differentially expressed proteins were analyzed using various bioinformatics tools.RESULTS Dapagliflozin significantly improved the clinical manifestation of the patients. There were 18 downregulated proteins and one upregulated protein in the serum samples of patients after dapagliflozin administration. Bioinformatics analyses, including subcellular localization, Eu Karyotic Orthologous Groups, Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes annotations, were used to profile the biological characteristics of the 19 differentially expressed proteins. Based on the literature and function enrichment analysis, two downregulated proteins, myeloperoxidase(MPO) and alpha Ⅱ B integrin(ITGA2B), and one upregulated protein, podocalyxin(PCX), were selected for enzyme linked immunosorbent assay validation. These validated differentially expressed proteins had multiple correlations with clinical indexes, including Hb Ac1 and fasting C-peptide.CONCLUSION Dapagliflozin has hypoglycemic effects and regulates the serum expressions of MPO, ITGA2B, and PCX, possibly contributing to the effects of dapagliflozin on oxidative stress, insulin resistance, and lipid metabolism.

UPLC-QTOF/MS Method for Screening and Determination of 59 Non-labeled Components in Veterinary Drug Preparations

[Objectives]This study was conducted to provide an accurate and reliable method for rapid high-throughput screening of veterinary drug preparations.[Methods]For the matrixes of veterinary drug preparations,high-performance liquid chromatography-high resolution quadrupole time-of-flight mass spectrometry(UPLC-QTOF/MS)was used to establish a fast screening method for 59 non-standard components in five categories of antiviral agents,aminoglycosides,quinolones,sulfonamides,and tetracyclines in veterinary drugs.The target drugs were separated by a Waters ACQUITY UPLC HSS T3 chromatographic column(50 mm×2.1 mm,1.8μm),and data were collected in the positive ion mode.Good separation of the 59 drugs was achieved within 7 min.[Results]In the concentration range of 0-100 ng/ml,each drug showed a good linear relationship,and the correlation coefficients were all greater than 0.999.The detection limits of the 59 drugs were in the range of 0.1-0.5 mg/ml,and the recovery under the addition concentration of 5 mg/ml was in the range of 85.2%-103.8%.[Conclusions]The method is fast,simple,accurate,and highly sensitive,and is suitable for high-throughput screening and qualitative identification of non-standard components in veterinary drug preparations.

Recent Developments of Image Based Measurement Methods for Application to Transonic Flows in Industrial Wind Tunnels

The experimental investigation of unsteady complex flow fields in wind tunnels requires advanced measurement techniques. The most important of such image based measurement techniques are those for the measurement of planar flow velocity fields, planar pressure distribution, model location and deformation, model temperature and quantitative high speed flow visualization. The applications as carried out by DLR range from low speed flows to transonic flows, from high lift configurations to propellers and rotors, from wake vortex investigations in catapult facilities and water towing tanks to investigations of vortex break down phenomena on delta wings. The capability to use image based measurement techniques in transonic flows requires dedicated technical developments and experienced scientists due to the special environment of a transonic wind tunnel. In this paper an overview of the state-of-the art of the application of image based measurement techniques in transonic flows as performed by DLR＇s Institute of Aerodynamics and Flow Technology will be given.

Square-Root Dynamics of a SIR-Model in Fractional Order

In this paper, we consider an SIR-model for which the interaction term is the square root of the susceptible and infected individuals in the form of fractional order differential equations. First the non-negative solution of the model in fractional order is presented. Then the local stability analysis of the model in fractional order is discussed. Finally, the general solutions are presented and a discrete-time finite difference scheme is constructed using the nonstandard finite difference (NSFD) method. A comparative study of the classical Runge-Kutta method and ODE45 is presented in the case of integer order derivatives. The solutions obtained are presented graphically.

Simulation Program to Determine Sample Size and Power for a Multiple Logistic Regression Model with Unspecified Covariate Distributions

Binary logistic regression models are commonly used to assess the association between outcomes and covariates. Many covariates are inherently continuous, and have a variety of distributions, including those that are heavily skewed to the left or right. Existing theoretical formulas, criteria, and simulation programs cannot accurately estimate the sample size and power of non-standard distributions. Therefore, we have developed a simulation program that uses Monte Carlo methods to estimate the exact power of a binary logistic regression model. This power calculation can be used for distributions of any shape and covariates of any type (continuous, ordinal, and nominal), and can account for nonlinear relationships between covariates and outcomes. For illustrative purposes, this simulation program is applied to real data obtained from a study on the influence of smoking on 90-day outcomes after acute atherothrombotic stroke. Our program is applicable to all effect sizes and makes it possible to apply various statistical methods, logistic regression and related simulations such as Bayesian inference with some modifications.

Modeling the Dynamics of Malaria Transmission with Bed Net Protection Perspective

We propose and analyze an epidemiological model to evaluate the effectiveness of bed nets as a prophylactic measure in malaria-endemic areas. The main purpose in this work is the modeling of the aggressiveness of anopheles mosquitoes relative to the way humans use to protect themselves against bites of mosquitoes. This model is a system of several differential equations: the number of equations depends on the particular assumptions of the model. We compute the basic reproduction number, and show that if, the disease free equilibrium (DFE) is globally asymptotically stable on the non-negative orthant. If, the system admits a unique endemic equilibrium (EE) that is globally and asymptotically stable. Numerical simulations are presented corresponding to scenarios typical of malaria-endemic areas, based on data collected in the literature. Finally, we discuss the relative effectiveness of different kinds of bed nets.

Shrinkage, Strength of High and Ordinary Concrete Incorporating Kosovo and Japanese Fly-ash

Ordinary and high performance concrete （OC-C 25/30 and HPC C-50/60） made with fly ash has found numerous applications all over the world since 1970. In Kosovo, fly ash as cement substitution in concrete has not been utilized yet despite the large amount that is produced annually and the positive economical-environment aspects of such technique. This hesitance is due to the laek of experience in the concrete engineering field and because of the chemical composition of Kosovo fly ash, which is classified as non-standard high calcium fly ash （KF）. In light of this fact, this study intended to develop further. So, this paper reports the consistency, workability, shrinkage, high and ordinary compressive strength of concrete containing different percentage of non-class high calcium fly ash as Portland cement substitution （first case-Kosovo fly ash KF） comparing results with F class-low caleium fly ash content （second ease-Japanese fly ash JF） which is common used as cement replacement.

An Expository on Some Nonstandard Compactifications

Three classical compactification procedures are presented with nonstandard flavour. This is to illustrate the applicability of Nonstandard analytic tool to beginners interested in Nonstandard analytic methods. The general procedure is as follows: A suitable equivalence relation is defined on an enlargement *X of the space X which is a completely regular space or a locally compact Hausdorff space or a locally compact Abelian group. Accordingly, every f in C(X,R) (the space of bounded continuous real valued functions on X) or Cc(X,R) (the space of continuous real valued functions on X with compact support) or the dual group Γ of the locally compact Abelian group G is extended to the set of the above mentioned equivalence classes. A compact topology on is obtained as the weak topology generated by these extensions of f. Then X is naturally imbedded densely in .

Design between Architecture and Structure: Case Studies of Pilot Interventions on Italian Monumental Buildings

Two case studies,referring to historic Italian buildings housing city halls,provide an opportunity to investigate the design of non-standard elements aimed at protecting masonry vaults,with particular reference to the preliminary works prior to the actual structural restoration work.There is in fact a phase in which it is a priority to secure the vault to avert possible risks to the users of that portion of the building.This phase is temporarily intermediate between the detection and aggravation of injuries and the renovation and consolidation project.Although these are provisional works,they are intended for buildings that are often public and therefore intended for a wide range of users,such as schools,offices or monumental buildings.In analyzing traditional techniques and systems used in similar cases,the possibility of developing evolutionary aspects with respect to,above all,simple shoring techniques emerged.In these areas,hybrids between a structural and architectural project,it is possible to reconcile static requirements with architectural techniques of space management,attentive to the quality of the interior and the integration of the provisional work with the reference context.

A Sociolinguistic Analysis of Language Use in“My Fair Lady”

My Fair Lady is one of the most famous musical movies in the world and for years, many people are obsessed with this movie.This paper will analyze the language use of two short excerpts in this movie from a sociolinguistic perspective. Some key sociolinguisticconcepts concerning conversations, such as standard/non-standard English, class, politeness and taboo, gender and phatic communication are to be explored and used in the analysis.

Charged-current non-standard neutrino interactions at the LHC and HL-LHC

A series of new physics scenarios predict the existence of the extra charged gauge boson W’,which can induce charged-current(CC)non-standard neutrino interactions(NSIs).The theoretical constraints on the simplified W’model and further on the CC NSI parameters ε_(αβ)^-qq'Y from partial wave unitarity and W’decays are considered.The sensitivity of the process pp→W’→lv to the W’model at the LHC and high-luminosity(HL)LHC experiments is investigated by estimating the expected constraints on ε_(αβ)^-qq'Y (α=β=e orμ)using a Monte-Carlo(MC)simulation.We find that the interference effect plays an important role,and the LHC can strongly constrain ε_(αβ)^-qq'L .Compared with those at the 13 TeV LHC with L=139 fb^(-1),the expected constraints at the 14TeV LHC with L=3 ab^(-1)can be strengthened to approximately one order of magnitude.

Comparative Analysis of Curing Methods:Natural and Activated Lateritic Concrete

This work was on non-activated and activated lateritic soil used in proportions of 0%to 30%,to replace fine sand by wt.%,in the production of lateritic concrete.A mix of 1:2:4 was used,and the cube samples were cured in four(4)curing media of water,sand,polythene,and sawdust.The aim was to evaluate the effects of these curing methods on the mechanical strengths,and other properties of lateritic concrete.The sensitivity of the generated data was characterized statistically and developing linear regression models for predictions.For the Non-Activated Laterite soil(NALS,control mix(0%)),the design strength of 20 MPa was achieved by all the curing methods(standard and non-standard).However,for other replacement levels,water curing was adequate for 10%and 30%,sand at 10%,and sawdust for 20%and 30%,respectively.On the other hand,for the Activated Laterite soil(ALS),the 20 MPa design strength was met only at 0%replacement for all curing methods.Sawdust medium at 10%also satisfied the 20 MPa strength.

Gravitational Field as a Pressure Force from Logarithmic Lagrangians and Non-Standard Hamiltonians：The Case of Stellar Halo of Milky Way

Recently,the notion of non-standard Lagrangians was discussed widely in literature in an attempt to explore the inverse variational problem of nonlinear differential equations.Different forms of non-standard Lagrangians were introduced in literature and have revealed nice mathematical and physical properties.One interesting form related to the inverse variational problem is the logarithmic Lagrangian,which has a number of motivating features related to the Li′enard-type and Emden nonlinear differential equations.Such types of Lagrangians lead to nonlinear dynamics based on non-standard Hamiltonians.In this communication,we show that some new dynamical properties are obtained in stellar dynamics if standard Lagrangians are replaced by Logarithmic Lagrangians and their corresponding non-standard Hamiltonians.One interesting consequence concerns the emergence of an extra pressure term,which is related to the gravitational field suggesting that gravitation may act as a pressure in a strong gravitational field.The case of the stellar halo of the Milky Way is considered.

On Non-standard Hilbert Functions

. Let S = k[x1,..., xn] be a non-standard polynomial ring over a field k and let M be a finitely generated graded S-module. In this paper, we investigate the behaviour of Hilbert function of M and its relations with lattice point counting. More precisely, by using combinatorial tools, we prove that there exists a polytope such that the image of Hilbert function in some degree is equal to the number of lattice points of this polytope.