This paper described T cell proliferative response by an alternative pathway in normal subjects and In patients with malignant diseases. Two McAbs, Anti-CCTl and Lo-CD2-act recognizing two distinct epitopes on E-recep...This paper described T cell proliferative response by an alternative pathway in normal subjects and In patients with malignant diseases. Two McAbs, Anti-CCTl and Lo-CD2-act recognizing two distinct epitopes on E-receptor (CD2) were used to costimulate PBMC. Proliferative responsiveness was measured by 3H-thymidine incorporation. It was found that 82% of 72 nonnal subjects gave proliferative response whereas only 23% of the 93 patients did. The average cpm±SD in patients with bladder cancer (118±2314), kidney cancer (1619±2719) or lymphoma (2518±4057) was significantly lower than that in normal subjects (4935±2314), (P<0.001). These results indicate that T cell proliferation through the alternative pathway was significantly depressed in patients with cancer, and this can be used as a new parameter to monitor the immune status of cancer patients.展开更多
IN July, 1993, an international seminar titled "Chinese Women and Development—Status, Health and Employment" was sponsored by the Women’s Studies Center at Tianjin Normal University. More than 100 internat...IN July, 1993, an international seminar titled "Chinese Women and Development—Status, Health and Employment" was sponsored by the Women’s Studies Center at Tianjin Normal University. More than 100 international and domestic specialists and workers who deal with women’s issues attended. At the conference, the Women’s Research Institute of the All-China Women’s Federation disclosed the results of an investigation about the status of women in China, which was launched in the early 1990s on a nationwide scale. The results showed that China’s economic reform has greatly affected women. As a result, many researchers who began their research by considering China’s present economic situation, tried to determine the influences the展开更多
文摘This paper described T cell proliferative response by an alternative pathway in normal subjects and In patients with malignant diseases. Two McAbs, Anti-CCTl and Lo-CD2-act recognizing two distinct epitopes on E-receptor (CD2) were used to costimulate PBMC. Proliferative responsiveness was measured by 3H-thymidine incorporation. It was found that 82% of 72 nonnal subjects gave proliferative response whereas only 23% of the 93 patients did. The average cpm±SD in patients with bladder cancer (118±2314), kidney cancer (1619±2719) or lymphoma (2518±4057) was significantly lower than that in normal subjects (4935±2314), (P<0.001). These results indicate that T cell proliferation through the alternative pathway was significantly depressed in patients with cancer, and this can be used as a new parameter to monitor the immune status of cancer patients.
文摘IN July, 1993, an international seminar titled "Chinese Women and Development—Status, Health and Employment" was sponsored by the Women’s Studies Center at Tianjin Normal University. More than 100 international and domestic specialists and workers who deal with women’s issues attended. At the conference, the Women’s Research Institute of the All-China Women’s Federation disclosed the results of an investigation about the status of women in China, which was launched in the early 1990s on a nationwide scale. The results showed that China’s economic reform has greatly affected women. As a result, many researchers who began their research by considering China’s present economic situation, tried to determine the influences the
