Enantiomerically pure a-substituted bamino esters were prepared from natural L-a-amino acids through Arndt-Eistert homologation and diastereoselective aalkylation.
Oxidation of perfluoroalkanesulfinate usually resulted in the formation of the correspon-ding sulfonyl derivatives,thus reaction with hydrogen peroxide or halogen（Cl,Br,I）gavesulfonic acid or sulfonyl halides.Howeve...Oxidation of perfluoroalkanesulfinate usually resulted in the formation of the correspon-ding sulfonyl derivatives,thus reaction with hydrogen peroxide or halogen（Cl,Br,I）gavesulfonic acid or sulfonyl halides.However in comparison with alkanesulfinate the perfluo-ro analog was shown to be relatively inert toward oxidizing agents.展开更多
基金The project is generously supported by the National Natural Science Foundation of China (Grant No. 29972002 20172002)+1 种基金 the Trans-Century Training Programme Foundation for the Talents by Ministry of Education and Bayer Co. Ltd (Germany). We thank Dr
文摘Enantiomerically pure a-substituted bamino esters were prepared from natural L-a-amino acids through Arndt-Eistert homologation and diastereoselective aalkylation.
文摘Oxidation of perfluoroalkanesulfinate usually resulted in the formation of the correspon-ding sulfonyl derivatives,thus reaction with hydrogen peroxide or halogen（Cl,Br,I）gavesulfonic acid or sulfonyl halides.However in comparison with alkanesulfinate the perfluo-ro analog was shown to be relatively inert toward oxidizing agents.
