In Algeria, as in all countries in the developing world, obesity has become more and more common in adults, suggesting a worsening of risk factors for cardiovascular disease and diabetes for these generations. This st...In Algeria, as in all countries in the developing world, obesity has become more and more common in adults, suggesting a worsening of risk factors for cardiovascular disease and diabetes for these generations. This study aims to assess the prevalence of obesity by anthropometry in adults in the city of Constantine over the year 2010-2011, and to explore its relationship with certain determining factors. A cross-sectional study with cluster sampling and stratification on sex allowed us to estimate the frequency of all categories of BMI. For this purpose, 320 adults living in Constantine were interviewed. In 2011, the prevalence of obesity was 35.84%. Women are more affected by obesity than men (40.83% vs. 22.08%). The prevalence of abdominal obesity, according to IDF, was 81.0% for women vs. 56.2% for men; according to NCEP ATP III, it was 64.3% in women vs. 35.9% in men. Obesity is more common in families of low socioeconomic status. Similarly, level of education and obesity are inversely correlated. People who have a sedentary lifestyle are more likely to be obese than those who are physically active. Obesity is a serious condition that results in significant health care costs. There is a need to undertake epidemiological surveillance in childhood. Urgent preventive actions are required. Promotion of a healthy balanced diet and physical exercise is a priority in the prevention of obesity.展开更多
Objective Assessment of the comprehensive relationship among apolipoprotein CIII(apoCⅢ) levels, inflammation, and metabolic disorders is rare. Methods A total of 1455 consecutive patients not treated with lipid-low...Objective Assessment of the comprehensive relationship among apolipoprotein CIII(apoCⅢ) levels, inflammation, and metabolic disorders is rare. Methods A total of 1455 consecutive patients not treated with lipid-lowering drugs and undergoing coronary angiography were enrolled in this cross-sectional study. A mediation analysis was used to detect the underlying role of apoCⅢ in the association of inflammation with metabolic syndrome(MetS). Results Patients with MetS showed higher levels of apoCⅢ [95.1(73.1-131.4) vs. 81.7(58.6-112.4) μg/mL, P 〈 0.001] and inflammatory markers [high sensitivity C-reactive protein, 1.7(0.8-3.4) vs. 1.1(0.5-2.2) mg/L; white blood cell count,(6.48 ± 1.68) vs.(6.11 ± 1.67) × 10~9/L]. The levels of apoCⅢ and inflammatory markers increased with the number of metabolic risk components(all P 〈 0.001). Furthermore, apoCⅢ levels were associated with virtually all individual MetS risk factors and inflammatory markers(all P 〈 0.05). Importantly, the prevalence of MetS in each metabolic disorder rose as apoCⅢ levels increased(all P 〈 0.05). Mediation analysis showed that apoCⅢ partially mediated the effect of inflammation on MetS independently from triglycerides. Conclusion Plasma apoCⅢ levels were significantly associated with the development and severity of MetS, and a role of apoCⅢ in the effect of inflammation on the development of MetS was identified.展开更多
Purpose Understanding the prevalence and trends of obesity in preschool children is of critical importance for public health policy.Thus,the object of the present study was to assess the prevalence and trends of obesi...Purpose Understanding the prevalence and trends of obesity in preschool children is of critical importance for public health policy.Thus,the object of the present study was to assess the prevalence and trends of obesity in Chinese preschool children from 1996 to 2019,and to examine the differences among different population according to year,gender,age,urban/rural and geographical area.Methods Four online databases(Chinese National Knowledge Infrastructure,Wanfang Data Resource System,Weipu Chi-nese Journal Service Platform and PubMed)were searched for studies published from January 1990 to May 2019 using predefined inclusion/exclusion criteria.Random effects meta-analysis was used to calculate the prevalence of obesity.Results Forty-three studies with a total of 765,255 Chinese preschool children aged 3-6 years were included in this meta-analysis.The prevalence of obesity in the whole sample was 6.41%(95%CI:5.74%-7.78%,P<0.000,I^(2)=99.79%;obtained after trim-and-fill adjustment).There was no significant difference(P=0.222)in the prevalence of obesity during five peri-ods(1996-2000,2001-2005,2006-2010,2011-2015,2016-2019).The obesity prevalence of boys was higher than girls(P=0.007),and the obesity prevalence increased with age(P=0.000).In 2006-2010,the prevalence of obesity among urban areas was about three times than that of rural areas(P=0.001).However,the difference was decreased during 2011-2015(P=0.788).In rural areas,the obesity prevalence in 2011-2015 was two times more than that in 2006-2010(P=0.005).Geographical area was a strong determinant of heterogeneity for Chinese preschool children(P=0.001).Conclusion There was no significant difference of the obesity prevalence among any five-year periods from 1996 to 2019.The prevalence of obesity in boys was higher than girls and increased with age.Though the prevalence of obesity in rural area was lower than the urban area,the speed of the increasing of the prevalence after 2010 in rural area should be noted.Public health intervention such as physical activity promotion and nutrition education should be conducted on preschool children for obesity prevention to promote their healthy development.展开更多
文摘In Algeria, as in all countries in the developing world, obesity has become more and more common in adults, suggesting a worsening of risk factors for cardiovascular disease and diabetes for these generations. This study aims to assess the prevalence of obesity by anthropometry in adults in the city of Constantine over the year 2010-2011, and to explore its relationship with certain determining factors. A cross-sectional study with cluster sampling and stratification on sex allowed us to estimate the frequency of all categories of BMI. For this purpose, 320 adults living in Constantine were interviewed. In 2011, the prevalence of obesity was 35.84%. Women are more affected by obesity than men (40.83% vs. 22.08%). The prevalence of abdominal obesity, according to IDF, was 81.0% for women vs. 56.2% for men; according to NCEP ATP III, it was 64.3% in women vs. 35.9% in men. Obesity is more common in families of low socioeconomic status. Similarly, level of education and obesity are inversely correlated. People who have a sedentary lifestyle are more likely to be obese than those who are physically active. Obesity is a serious condition that results in significant health care costs. There is a need to undertake epidemiological surveillance in childhood. Urgent preventive actions are required. Promotion of a healthy balanced diet and physical exercise is a priority in the prevention of obesity.
基金partially supported by the Capital Special Foundation of Clinical Application Research(Z121107001012015)the Capital Health Development Fund(2011400302,201614035)+1 种基金the Beijing Natural Science Foundation(7131014)CAMS Major Collaborative Innovation Project(2016-I2M-1-011)
文摘Objective Assessment of the comprehensive relationship among apolipoprotein CIII(apoCⅢ) levels, inflammation, and metabolic disorders is rare. Methods A total of 1455 consecutive patients not treated with lipid-lowering drugs and undergoing coronary angiography were enrolled in this cross-sectional study. A mediation analysis was used to detect the underlying role of apoCⅢ in the association of inflammation with metabolic syndrome(MetS). Results Patients with MetS showed higher levels of apoCⅢ [95.1(73.1-131.4) vs. 81.7(58.6-112.4) μg/mL, P 〈 0.001] and inflammatory markers [high sensitivity C-reactive protein, 1.7(0.8-3.4) vs. 1.1(0.5-2.2) mg/L; white blood cell count,(6.48 ± 1.68) vs.(6.11 ± 1.67) × 10~9/L]. The levels of apoCⅢ and inflammatory markers increased with the number of metabolic risk components(all P 〈 0.001). Furthermore, apoCⅢ levels were associated with virtually all individual MetS risk factors and inflammatory markers(all P 〈 0.05). Importantly, the prevalence of MetS in each metabolic disorder rose as apoCⅢ levels increased(all P 〈 0.05). Mediation analysis showed that apoCⅢ partially mediated the effect of inflammation on MetS independently from triglycerides. Conclusion Plasma apoCⅢ levels were significantly associated with the development and severity of MetS, and a role of apoCⅢ in the effect of inflammation on the development of MetS was identified.
基金supported by“the Fundamental Research Funds for the Central Universities(Beijing Sport University 2020047)”.
文摘Purpose Understanding the prevalence and trends of obesity in preschool children is of critical importance for public health policy.Thus,the object of the present study was to assess the prevalence and trends of obesity in Chinese preschool children from 1996 to 2019,and to examine the differences among different population according to year,gender,age,urban/rural and geographical area.Methods Four online databases(Chinese National Knowledge Infrastructure,Wanfang Data Resource System,Weipu Chi-nese Journal Service Platform and PubMed)were searched for studies published from January 1990 to May 2019 using predefined inclusion/exclusion criteria.Random effects meta-analysis was used to calculate the prevalence of obesity.Results Forty-three studies with a total of 765,255 Chinese preschool children aged 3-6 years were included in this meta-analysis.The prevalence of obesity in the whole sample was 6.41%(95%CI:5.74%-7.78%,P<0.000,I^(2)=99.79%;obtained after trim-and-fill adjustment).There was no significant difference(P=0.222)in the prevalence of obesity during five peri-ods(1996-2000,2001-2005,2006-2010,2011-2015,2016-2019).The obesity prevalence of boys was higher than girls(P=0.007),and the obesity prevalence increased with age(P=0.000).In 2006-2010,the prevalence of obesity among urban areas was about three times than that of rural areas(P=0.001).However,the difference was decreased during 2011-2015(P=0.788).In rural areas,the obesity prevalence in 2011-2015 was two times more than that in 2006-2010(P=0.005).Geographical area was a strong determinant of heterogeneity for Chinese preschool children(P=0.001).Conclusion There was no significant difference of the obesity prevalence among any five-year periods from 1996 to 2019.The prevalence of obesity in boys was higher than girls and increased with age.Though the prevalence of obesity in rural area was lower than the urban area,the speed of the increasing of the prevalence after 2010 in rural area should be noted.Public health intervention such as physical activity promotion and nutrition education should be conducted on preschool children for obesity prevention to promote their healthy development.