Structural development defects essentially refer to code structure that violates object-oriented design principles. They make program maintenance challenging and deteriorate software quality over time. Various detecti...Structural development defects essentially refer to code structure that violates object-oriented design principles. They make program maintenance challenging and deteriorate software quality over time. Various detection approaches, ranging from traditional heuristic algorithms to machine learning methods, are used to identify these defects. Ensemble learning methods have strengthened the detection of these defects. However, existing approaches do not simultaneously exploit the capabilities of extracting relevant features from pre-trained models and the performance of neural networks for the classification task. Therefore, our goal has been to design a model that combines a pre-trained model to extract relevant features from code excerpts through transfer learning and a bagging method with a base estimator, a dense neural network, for defect classification. To achieve this, we composed multiple samples of the same size with replacements from the imbalanced dataset MLCQ1. For all the samples, we used the CodeT5-small variant to extract features and trained a bagging method with the neural network Roberta Classification Head to classify defects based on these features. We then compared this model to RandomForest, one of the ensemble methods that yields good results. Our experiments showed that the number of base estimators to use for bagging depends on the defect to be detected. Next, we observed that it was not necessary to use a data balancing technique with our model when the imbalance rate was 23%. Finally, for blob detection, RandomForest had a median MCC value of 0.36 compared to 0.12 for our method. However, our method was predominant in Long Method detection with a median MCC value of 0.53 compared to 0.42 for RandomForest. These results suggest that the performance of ensemble methods in detecting structural development defects is dependent on specific defects.展开更多
The design of finite element analysis program using object-oriented programming (OOP) techniques is presented. The objects, classes and the subclasses used in the programming are explained. The system of classes libra...The design of finite element analysis program using object-oriented programming (OOP) techniques is presented. The objects, classes and the subclasses used in the programming are explained. The system of classes library of finite element analysis program and Windows-type Graphical User Interfaces by VC + + and its MFC are developed. The reliability, reusability and extensibility of program are enhanced. It is a reference to develop the large-scale, versatile and powerful systems of object-oriented finite element software.展开更多
A multi-objective linear programming problem is made from fuzzy linear programming problem. It is due the fact that it is used fuzzy programming method during the solution. The Multi objective linear programming probl...A multi-objective linear programming problem is made from fuzzy linear programming problem. It is due the fact that it is used fuzzy programming method during the solution. The Multi objective linear programming problem can be converted into the single objective function by various methods as Chandra Sen’s method, weighted sum method, ranking function method, statistical averaging method. In this paper, Chandra Sen’s method and statistical averaging method both are used here for making single objective function from multi-objective function. Two multi-objective programming problems are solved to verify the result. One is numerical example and the other is real life example. Then the problems are solved by ordinary simplex method and fuzzy programming method. It can be seen that fuzzy programming method gives better optimal values than the ordinary simplex method.展开更多
Detecting well-known design patterns in object-oriented program source code can help maintainers understand the design of a program. Through the detection, the understandability, maintainability, and reusability of ob...Detecting well-known design patterns in object-oriented program source code can help maintainers understand the design of a program. Through the detection, the understandability, maintainability, and reusability of object-oriented programs can be improved. There are automated detection techniques;however, many existing techniques are based on static analysis and use strict conditions composed on class structure data. Hence, it is difficult for them to detect and distinguish design patterns in which the class structures are similar. Moreover, it is difficult for them to deal with diversity in design pattern applications. To solve these problems in existing techniques, we propose a design pattern detection technique using source code metrics and machine learning. Our technique judges candidates for the roles that compose design patterns by using machine learning and measurements of several metrics, and it detects design patterns by analyzing the relations between candidates. It suppresses false negatives and distinguishes patterns in which the class structures are similar. As a result of experimental evaluations with a set of programs, we confirmed that our technique is more accurate than two conventional techniques.展开更多
In this paper, some necessary and sufficient optimality conditions are obtained for a fractional multiple objective programming involving semilocal E-convex and related functions. Also, some dual results are establish...In this paper, some necessary and sufficient optimality conditions are obtained for a fractional multiple objective programming involving semilocal E-convex and related functions. Also, some dual results are established under this kind of generalized convex functions. Our results generalize the ones obtained by Preda[J Math Anal Appl, 288(2003) 365-382].展开更多
The principal-subordinate hierarchical multi-objective programming model of initial water rights allocation was developed based on the principle of coordinated and sustainable development of different regions and wate...The principal-subordinate hierarchical multi-objective programming model of initial water rights allocation was developed based on the principle of coordinated and sustainable development of different regions and water sectors within a basin. With the precondition of strictly controlling maximum emissions rights, initial water rights were allocated between the first and the second levels of the hierarchy in order to promote fair and coordinated development across different regions of the basin and coordinated and efficient water use across different water sectors, realize the maximum comprehensive benefits to the basin, promote the unity of quantity and quality of initial water rights allocation, and eliminate water conflict across different regions and water sectors. According to interactive decision-making theory, a principal-subordinate hierarchical interactive iterative algorithm based on the satisfaction degree was developed and used to solve the initial water rights allocation model. A case study verified the validity of the model.展开更多
An uncertain multi-objective programming problem is a special type of mathematical multi-objective programming involving uncertain variables. This type of problem is important because there are several uncertain varia...An uncertain multi-objective programming problem is a special type of mathematical multi-objective programming involving uncertain variables. This type of problem is important because there are several uncertain variables in real-world problems.Therefore, research on the uncertain multi-objective programming problem is highly relevant, particularly those problems whose objective functions are correlated. In this paper, an approach that solves an uncertain multi-objective programming problem under the expected-variance value criterion is proposed. First, we define the basic framework of the approach and review concepts such as a Pareto efficient solution and expected-variance value criterion using an order relation between various uncertain variables.Second, the uncertain multi-objective problem is converted into an uncertain single-objective programming problem via a linear weighted method or ideal point method. Then the problem is transformed into a deterministic single objective programming problem under the expected-variance value criterion. Third, four lemmas and two theorems are proved to illustrate that the optimal solution of the deterministic single-objective programming problem is an efficient solution to the original uncertainty problem. Finally, two numerical examples are presented to validate the effectiveness of the proposed approach.展开更多
An object oriented multi robotic graphic simulation environment is described in this paper. Object oriented programming is used to model the physical objects of the robotic workcell in the form of software objects ...An object oriented multi robotic graphic simulation environment is described in this paper. Object oriented programming is used to model the physical objects of the robotic workcell in the form of software objects or classes. The virtual objects are defined to provide the user with a user friendly interface including realistic graphic simulation and clarify the software architecture. The programming method of associating the task object with active object effectively increases the software reusability, maintainability and modifiability. Task level programming is also demonstrated through a multi robot welding task that allows the user to concentrate on the most important aspects of the tasks. The multi thread programming technique is used to simulate the interaction of multiple tasks. Finally, a virtual test is carried out in the graphic simulation environment to observe design and program errors and fix them before downloading the software to the real workcell.展开更多
A primal-dual infeasible interior point algorithm for multiple objective linear programming (MOLP) problems was presented. In contrast to the current MOLP algorithm. moving through the interior of polytope but not con...A primal-dual infeasible interior point algorithm for multiple objective linear programming (MOLP) problems was presented. In contrast to the current MOLP algorithm. moving through the interior of polytope but not confining the iterates within the feasible region in our proposed algorithm result in a solution approach that is quite different and less sensitive to problem size, so providing the potential to dramatically improve the practical computation effectiveness.展开更多
To simulate the process of cold roll-forming process, a new method isadopted. The theoretical foundation of this method is an elastic-plastic large deformation splinefinite strip method based on object-oriented progra...To simulate the process of cold roll-forming process, a new method isadopted. The theoretical foundation of this method is an elastic-plastic large deformation splinefinite strip method based on object-oriented programming. Combined with the computer graphicstechnology, the visual simulation of cold roll-forming is completed and the system is established.By analyzing common channel steel, the process is shown and explained including theory method, modeland result display. So the simulation system is already a kind of mature and effective tool toanalyze the process of cold roll forming.展开更多
The objective of the present study is to develop the irrigation planning model and to apply the same in the form of Two-Phase Multi Objective Fuzzy Linear Programming (TPMOFLP) approach for crop planning in command ar...The objective of the present study is to develop the irrigation planning model and to apply the same in the form of Two-Phase Multi Objective Fuzzy Linear Programming (TPMOFLP) approach for crop planning in command area of Jayakwadi Project Stage I, Maharashtra State, India. The development of TPMOFLP model is on the basis of various Linear Programming (LP) models and Multi Objective Fuzzy Linear Programming (MOFLP) models, these models have been applied for maximization of the Net Benefits (NB), Crop production (CP), Employment Generation (EG) and Manure Utilization (MU) respectively. The significant increase in the value of level of satisfaction (λ) has been found from 0.58 to 0.65 by using the TPMOFLP approach as compare to that of MOFLP model based on maxmin approach. The two-phase approach solution provides NB = 1503.56 Million Rupees, CP = 335729.30 Tons, EG = 29.74 Million Man days and MU = 160233.70 Tons respectively. The proposed model will be helpful for the Decision Maker (DM) to take a decision under conflicting situation while planning for different conflicting objectives simultaneously and has potential to find out an integrated irrigation planning with prime consideration for economic, social and environmental issue.展开更多
BACKGROUND The combination of programmed cell death protein-1(PD-1)inhibitor and che-motherapy is approved as a standard first-or second-line treatment in patients with advanced oesophageal or gastric cancer.However,i...BACKGROUND The combination of programmed cell death protein-1(PD-1)inhibitor and che-motherapy is approved as a standard first-or second-line treatment in patients with advanced oesophageal or gastric cancer.However,it is unclear whether this combination is superior to chemotherapy alone.AIM To assess the comparative effectiveness and tolerability of combining PD-1 inhibitors with chemotherapy vs chemotherapy alone in patients with advanced gastric cancer,gastroesophageal junction(GEJ)cancer,or oesophageal carcinoma.METHODS We searched the PubMed and Embase databases for studies that compared the efficacy and tolerance of PD-1 inhibitors in combination with chemotherapy vs chemotherapy alone in patients with advanced oesophageal or gastric cancer.We employed either random or fixed models to analyze the outcomes of each clinical trial,en-compassing data on overall survival(OS),progression-free survival(PFS),objective response rate,and adverse events(AEs).RESULTS Nine phase 3 clinical trials(7016 advanced oesophageal and gastric cancer patients)met the inclusion criteria.Our meta-analysis demonstrated that the pooled PD-1 inhibitor+chemotherapy group had a significantly longer OS than the chemotherapy-alone group[hazard ratio(HR)=0.76,95%confidence interval(CI):0.71-0.81];the pooled PFS result was consistent with that of OS(HR=0.67,95%CI:0.61-0.74).The count of patients achieving an objective response in the PD-1 inhibitor+chemotherapy group surpassed that of the chemotherapy-alone group[odds ratio(OR)=1.86,95%CI:1.59-2.18].AE incidence was also higher in the combination-therapy group than in the chemotherapy-alone group,regardless of whether≥grade 3 only(OR=1.30,95%CI:1.07-1.57)or all AE grades(OR=1.88,95%CI:1.39-2.54)were examined.We performed a subgroup analysis based on the programmed death-ligand 1(PD-L1)combined positive score(CPS)and noted extended OS and PFS durations within the CPS≥1,CPS≥5,and CPS≥10 subgroups of the PD-1 inhibitor+chemotherapy group.CONCLUSION In contrast to chemotherapy alone,the combination of PD-1 inhibitor and chemotherapy appears to present a more favorable option for initial or subsequent treatment in patients with gastric cancer,GEJ tumor,or oesophageal cancer.This holds true particularly for individuals with PD-L1 CPS scores of≥5 and≥10.展开更多
A scheme for general purposed FDTD visual scientific computing software is introduced in this paper using object-oriented design (OOD) method. By abstracting the parameters of FDTD grids to an individual class and sep...A scheme for general purposed FDTD visual scientific computing software is introduced in this paper using object-oriented design (OOD) method. By abstracting the parameters of FDTD grids to an individual class and separating from the iteration procedure, the visual software can be adapted to more comprehensive computing problems. Real-time gray degree graphic and wave curve of the results can be achieved using DirectX technique. The special difference equation and data structure in dispersive medium are considered, and the peculiarity of parameters in perfectly matched layer are also discussed.展开更多
The traditional linear programming model is deterministic. The way that uncertainty is handled is to compute the range of optimality. After the optimal solution is obtained, typically by the simplex method, one consid...The traditional linear programming model is deterministic. The way that uncertainty is handled is to compute the range of optimality. After the optimal solution is obtained, typically by the simplex method, one considers the effect of varying each objective function coefficient, one at a time. This yields the range of optimality within which the decision variables remain constant. This sensitivity analysis is useful for helping the analyst get a sense for the problem. However, it is unrealistic because objective function coefficients tend not to stand still. They are typically profit contributions from products sold and are subject to randomly varying selling prices. In this paper, a realistic linear program is created for simultaneously randomizing the coefficients from any probability distribution. Furthermore, we present a novel approach for designing a copula of random objective function coefficients according to a specified rank correlation. The corresponding distribution of objective function values is created. This distribution is examined directly for central tendency, spread, skewness and extreme values for the purpose of risk analysis. This enables risk analysis and business analytics, emerging topics in education and preparation for the knowledge economy.展开更多
In this paper, we present an algorithm to solve the inequality constrained multi-objective programming (MP) by using a penalty function with objective parameters and constraint penalty parameter. First, the penalty fu...In this paper, we present an algorithm to solve the inequality constrained multi-objective programming (MP) by using a penalty function with objective parameters and constraint penalty parameter. First, the penalty function with objective parameters and constraint penalty parameter for MP and the corresponding unconstraint penalty optimization problem (UPOP) is defined. Under some conditions, a Pareto efficient solution (or a weakly-efficient solution) to UPOP is proved to be a Pareto efficient solution (or a weakly-efficient solution) to MP. The penalty function is proved to be exact under a stable condition. Then, we design an algorithm to solve MP and prove its convergence. Finally, numerical examples show that the algorithm may help decision makers to find a satisfactory solution to MP.展开更多
In this paper we discuss about infeasibility diagnosis and infeasibility resolution, when the constraint method is used for solving multi objective linear programming problems. We propose an algorithm for resolution o...In this paper we discuss about infeasibility diagnosis and infeasibility resolution, when the constraint method is used for solving multi objective linear programming problems. We propose an algorithm for resolution of infeasibility, which is a combination of interactive, weighting and constraint methods.Numerical examples are provided to illustrate the techniques developed.展开更多
Students often face difficulties while taking basic programming courses due to several factors. In response, research has presented subjective assessments for diagnosing learning problems to improve the teaching of pr...Students often face difficulties while taking basic programming courses due to several factors. In response, research has presented subjective assessments for diagnosing learning problems to improve the teaching of programming in higher education. In this paper, the authors propose an Object Oriented conceptual map model and organize this approach into three levels: constructing a Concept Effect Propagation Table, constructing Test Item-Concept Relationships and diagnosing Student Learning Problems with Matrix Composition. The authors' work is a modification of the approaches of Chert and Bai as well as Chu et al., as the authors use statistical methods, rather than fuzzy sets, for the authors' analysis. This paper includes a statistical summary, which has been tested on a small sample of students in King Abdulaziz University, Jeddah, Saudi Arabia, illustrating the learning problems in an Object Oriented course. The experimental results have demonstrated that this approach might aid learning and teaching in an effective way.展开更多
According to Hainan Island's biological characteristics, and existing structure of productivity of tropical crops and local climatic conditions, this paper carries on regional division of tropical crops by fuzzy m...According to Hainan Island's biological characteristics, and existing structure of productivity of tropical crops and local climatic conditions, this paper carries on regional division of tropical crops by fuzzy mathematics. Based on calculation of basic parameters for tl1e formation of production, near-tem optimum models of tropical crops structure of each region was established by means of multi-objective programming, and a far-term grey programming model was set up through the above-mentioned near-term model and prediction of future parameters. Conclusion shows that the near-term programming may raise the profit by 5. 1-55.7 percent and far-tem programming by 54-90 percent, both gainingobvious economic benefits.展开更多
In this paper, a modified method to find the efficient solutions of multi-objective linear fractional programming (MOLFP) problems is presented. While some of the previously proposed methods provide only one efficient...In this paper, a modified method to find the efficient solutions of multi-objective linear fractional programming (MOLFP) problems is presented. While some of the previously proposed methods provide only one efficient solution to the MOLFP problem, this modified method provides multiple efficient solutions to the problem. As a result, it provides the decision makers flexibility to choose a better option from alternatives according to their financial position and their level of satisfaction of objectives. A numerical example is provided to illustrate the modified method and also a real life oriented production problem is modeled and solved.展开更多
This paper describes the object-oriented implementational method of finite element structural analysis, gives the basic concepts of the object-oriented method and objectoriented programming, develops a complete class ...This paper describes the object-oriented implementational method of finite element structural analysis, gives the basic concepts of the object-oriented method and objectoriented programming, develops a complete class hierarchy structure of object-oriented finite element structural analysis, and gives a part C+ + code description.展开更多
文摘Structural development defects essentially refer to code structure that violates object-oriented design principles. They make program maintenance challenging and deteriorate software quality over time. Various detection approaches, ranging from traditional heuristic algorithms to machine learning methods, are used to identify these defects. Ensemble learning methods have strengthened the detection of these defects. However, existing approaches do not simultaneously exploit the capabilities of extracting relevant features from pre-trained models and the performance of neural networks for the classification task. Therefore, our goal has been to design a model that combines a pre-trained model to extract relevant features from code excerpts through transfer learning and a bagging method with a base estimator, a dense neural network, for defect classification. To achieve this, we composed multiple samples of the same size with replacements from the imbalanced dataset MLCQ1. For all the samples, we used the CodeT5-small variant to extract features and trained a bagging method with the neural network Roberta Classification Head to classify defects based on these features. We then compared this model to RandomForest, one of the ensemble methods that yields good results. Our experiments showed that the number of base estimators to use for bagging depends on the defect to be detected. Next, we observed that it was not necessary to use a data balancing technique with our model when the imbalance rate was 23%. Finally, for blob detection, RandomForest had a median MCC value of 0.36 compared to 0.12 for our method. However, our method was predominant in Long Method detection with a median MCC value of 0.53 compared to 0.42 for RandomForest. These results suggest that the performance of ensemble methods in detecting structural development defects is dependent on specific defects.
文摘The design of finite element analysis program using object-oriented programming (OOP) techniques is presented. The objects, classes and the subclasses used in the programming are explained. The system of classes library of finite element analysis program and Windows-type Graphical User Interfaces by VC + + and its MFC are developed. The reliability, reusability and extensibility of program are enhanced. It is a reference to develop the large-scale, versatile and powerful systems of object-oriented finite element software.
文摘A multi-objective linear programming problem is made from fuzzy linear programming problem. It is due the fact that it is used fuzzy programming method during the solution. The Multi objective linear programming problem can be converted into the single objective function by various methods as Chandra Sen’s method, weighted sum method, ranking function method, statistical averaging method. In this paper, Chandra Sen’s method and statistical averaging method both are used here for making single objective function from multi-objective function. Two multi-objective programming problems are solved to verify the result. One is numerical example and the other is real life example. Then the problems are solved by ordinary simplex method and fuzzy programming method. It can be seen that fuzzy programming method gives better optimal values than the ordinary simplex method.
文摘Detecting well-known design patterns in object-oriented program source code can help maintainers understand the design of a program. Through the detection, the understandability, maintainability, and reusability of object-oriented programs can be improved. There are automated detection techniques;however, many existing techniques are based on static analysis and use strict conditions composed on class structure data. Hence, it is difficult for them to detect and distinguish design patterns in which the class structures are similar. Moreover, it is difficult for them to deal with diversity in design pattern applications. To solve these problems in existing techniques, we propose a design pattern detection technique using source code metrics and machine learning. Our technique judges candidates for the roles that compose design patterns by using machine learning and measurements of several metrics, and it detects design patterns by analyzing the relations between candidates. It suppresses false negatives and distinguishes patterns in which the class structures are similar. As a result of experimental evaluations with a set of programs, we confirmed that our technique is more accurate than two conventional techniques.
基金Foundation item: Supported by Hunan Provincial Natural Science Foundation of China(05JJ40103) Supported by Soft Science Research Fund of Hunan Province(2006ZK3028) Supported by Scientific Research Fund of Hunan Provincial Education Department(105B0707, 08C470)
文摘In this paper, some necessary and sufficient optimality conditions are obtained for a fractional multiple objective programming involving semilocal E-convex and related functions. Also, some dual results are established under this kind of generalized convex functions. Our results generalize the ones obtained by Preda[J Math Anal Appl, 288(2003) 365-382].
基金supported by the Public Welfare Industry Special Fund Project of the Ministry of Water Resources of China (Grant No. 200701028)the Humanities and Social Science Foundation Program of Hohai University (Grant No. 2008421411)
文摘The principal-subordinate hierarchical multi-objective programming model of initial water rights allocation was developed based on the principle of coordinated and sustainable development of different regions and water sectors within a basin. With the precondition of strictly controlling maximum emissions rights, initial water rights were allocated between the first and the second levels of the hierarchy in order to promote fair and coordinated development across different regions of the basin and coordinated and efficient water use across different water sectors, realize the maximum comprehensive benefits to the basin, promote the unity of quantity and quality of initial water rights allocation, and eliminate water conflict across different regions and water sectors. According to interactive decision-making theory, a principal-subordinate hierarchical interactive iterative algorithm based on the satisfaction degree was developed and used to solve the initial water rights allocation model. A case study verified the validity of the model.
基金supported by the National Natural Science Foundation of China(71601183 71571190)
文摘An uncertain multi-objective programming problem is a special type of mathematical multi-objective programming involving uncertain variables. This type of problem is important because there are several uncertain variables in real-world problems.Therefore, research on the uncertain multi-objective programming problem is highly relevant, particularly those problems whose objective functions are correlated. In this paper, an approach that solves an uncertain multi-objective programming problem under the expected-variance value criterion is proposed. First, we define the basic framework of the approach and review concepts such as a Pareto efficient solution and expected-variance value criterion using an order relation between various uncertain variables.Second, the uncertain multi-objective problem is converted into an uncertain single-objective programming problem via a linear weighted method or ideal point method. Then the problem is transformed into a deterministic single objective programming problem under the expected-variance value criterion. Third, four lemmas and two theorems are proved to illustrate that the optimal solution of the deterministic single-objective programming problem is an efficient solution to the original uncertainty problem. Finally, two numerical examples are presented to validate the effectiveness of the proposed approach.
文摘An object oriented multi robotic graphic simulation environment is described in this paper. Object oriented programming is used to model the physical objects of the robotic workcell in the form of software objects or classes. The virtual objects are defined to provide the user with a user friendly interface including realistic graphic simulation and clarify the software architecture. The programming method of associating the task object with active object effectively increases the software reusability, maintainability and modifiability. Task level programming is also demonstrated through a multi robot welding task that allows the user to concentrate on the most important aspects of the tasks. The multi thread programming technique is used to simulate the interaction of multiple tasks. Finally, a virtual test is carried out in the graphic simulation environment to observe design and program errors and fix them before downloading the software to the real workcell.
基金Supported by the Doctoral Educational Foundation of China of the Ministry of Education(20020486035)
文摘A primal-dual infeasible interior point algorithm for multiple objective linear programming (MOLP) problems was presented. In contrast to the current MOLP algorithm. moving through the interior of polytope but not confining the iterates within the feasible region in our proposed algorithm result in a solution approach that is quite different and less sensitive to problem size, so providing the potential to dramatically improve the practical computation effectiveness.
基金This project is supported by Provincial Natural Science Foundation of Hebei (No.502214).
文摘To simulate the process of cold roll-forming process, a new method isadopted. The theoretical foundation of this method is an elastic-plastic large deformation splinefinite strip method based on object-oriented programming. Combined with the computer graphicstechnology, the visual simulation of cold roll-forming is completed and the system is established.By analyzing common channel steel, the process is shown and explained including theory method, modeland result display. So the simulation system is already a kind of mature and effective tool toanalyze the process of cold roll forming.
文摘The objective of the present study is to develop the irrigation planning model and to apply the same in the form of Two-Phase Multi Objective Fuzzy Linear Programming (TPMOFLP) approach for crop planning in command area of Jayakwadi Project Stage I, Maharashtra State, India. The development of TPMOFLP model is on the basis of various Linear Programming (LP) models and Multi Objective Fuzzy Linear Programming (MOFLP) models, these models have been applied for maximization of the Net Benefits (NB), Crop production (CP), Employment Generation (EG) and Manure Utilization (MU) respectively. The significant increase in the value of level of satisfaction (λ) has been found from 0.58 to 0.65 by using the TPMOFLP approach as compare to that of MOFLP model based on maxmin approach. The two-phase approach solution provides NB = 1503.56 Million Rupees, CP = 335729.30 Tons, EG = 29.74 Million Man days and MU = 160233.70 Tons respectively. The proposed model will be helpful for the Decision Maker (DM) to take a decision under conflicting situation while planning for different conflicting objectives simultaneously and has potential to find out an integrated irrigation planning with prime consideration for economic, social and environmental issue.
文摘BACKGROUND The combination of programmed cell death protein-1(PD-1)inhibitor and che-motherapy is approved as a standard first-or second-line treatment in patients with advanced oesophageal or gastric cancer.However,it is unclear whether this combination is superior to chemotherapy alone.AIM To assess the comparative effectiveness and tolerability of combining PD-1 inhibitors with chemotherapy vs chemotherapy alone in patients with advanced gastric cancer,gastroesophageal junction(GEJ)cancer,or oesophageal carcinoma.METHODS We searched the PubMed and Embase databases for studies that compared the efficacy and tolerance of PD-1 inhibitors in combination with chemotherapy vs chemotherapy alone in patients with advanced oesophageal or gastric cancer.We employed either random or fixed models to analyze the outcomes of each clinical trial,en-compassing data on overall survival(OS),progression-free survival(PFS),objective response rate,and adverse events(AEs).RESULTS Nine phase 3 clinical trials(7016 advanced oesophageal and gastric cancer patients)met the inclusion criteria.Our meta-analysis demonstrated that the pooled PD-1 inhibitor+chemotherapy group had a significantly longer OS than the chemotherapy-alone group[hazard ratio(HR)=0.76,95%confidence interval(CI):0.71-0.81];the pooled PFS result was consistent with that of OS(HR=0.67,95%CI:0.61-0.74).The count of patients achieving an objective response in the PD-1 inhibitor+chemotherapy group surpassed that of the chemotherapy-alone group[odds ratio(OR)=1.86,95%CI:1.59-2.18].AE incidence was also higher in the combination-therapy group than in the chemotherapy-alone group,regardless of whether≥grade 3 only(OR=1.30,95%CI:1.07-1.57)or all AE grades(OR=1.88,95%CI:1.39-2.54)were examined.We performed a subgroup analysis based on the programmed death-ligand 1(PD-L1)combined positive score(CPS)and noted extended OS and PFS durations within the CPS≥1,CPS≥5,and CPS≥10 subgroups of the PD-1 inhibitor+chemotherapy group.CONCLUSION In contrast to chemotherapy alone,the combination of PD-1 inhibitor and chemotherapy appears to present a more favorable option for initial or subsequent treatment in patients with gastric cancer,GEJ tumor,or oesophageal cancer.This holds true particularly for individuals with PD-L1 CPS scores of≥5 and≥10.
基金This project was supported by the National Natural Science Foundation (No. 69831020).
文摘A scheme for general purposed FDTD visual scientific computing software is introduced in this paper using object-oriented design (OOD) method. By abstracting the parameters of FDTD grids to an individual class and separating from the iteration procedure, the visual software can be adapted to more comprehensive computing problems. Real-time gray degree graphic and wave curve of the results can be achieved using DirectX technique. The special difference equation and data structure in dispersive medium are considered, and the peculiarity of parameters in perfectly matched layer are also discussed.
文摘The traditional linear programming model is deterministic. The way that uncertainty is handled is to compute the range of optimality. After the optimal solution is obtained, typically by the simplex method, one considers the effect of varying each objective function coefficient, one at a time. This yields the range of optimality within which the decision variables remain constant. This sensitivity analysis is useful for helping the analyst get a sense for the problem. However, it is unrealistic because objective function coefficients tend not to stand still. They are typically profit contributions from products sold and are subject to randomly varying selling prices. In this paper, a realistic linear program is created for simultaneously randomizing the coefficients from any probability distribution. Furthermore, we present a novel approach for designing a copula of random objective function coefficients according to a specified rank correlation. The corresponding distribution of objective function values is created. This distribution is examined directly for central tendency, spread, skewness and extreme values for the purpose of risk analysis. This enables risk analysis and business analytics, emerging topics in education and preparation for the knowledge economy.
文摘In this paper, we present an algorithm to solve the inequality constrained multi-objective programming (MP) by using a penalty function with objective parameters and constraint penalty parameter. First, the penalty function with objective parameters and constraint penalty parameter for MP and the corresponding unconstraint penalty optimization problem (UPOP) is defined. Under some conditions, a Pareto efficient solution (or a weakly-efficient solution) to UPOP is proved to be a Pareto efficient solution (or a weakly-efficient solution) to MP. The penalty function is proved to be exact under a stable condition. Then, we design an algorithm to solve MP and prove its convergence. Finally, numerical examples show that the algorithm may help decision makers to find a satisfactory solution to MP.
文摘In this paper we discuss about infeasibility diagnosis and infeasibility resolution, when the constraint method is used for solving multi objective linear programming problems. We propose an algorithm for resolution of infeasibility, which is a combination of interactive, weighting and constraint methods.Numerical examples are provided to illustrate the techniques developed.
文摘Students often face difficulties while taking basic programming courses due to several factors. In response, research has presented subjective assessments for diagnosing learning problems to improve the teaching of programming in higher education. In this paper, the authors propose an Object Oriented conceptual map model and organize this approach into three levels: constructing a Concept Effect Propagation Table, constructing Test Item-Concept Relationships and diagnosing Student Learning Problems with Matrix Composition. The authors' work is a modification of the approaches of Chert and Bai as well as Chu et al., as the authors use statistical methods, rather than fuzzy sets, for the authors' analysis. This paper includes a statistical summary, which has been tested on a small sample of students in King Abdulaziz University, Jeddah, Saudi Arabia, illustrating the learning problems in an Object Oriented course. The experimental results have demonstrated that this approach might aid learning and teaching in an effective way.
文摘According to Hainan Island's biological characteristics, and existing structure of productivity of tropical crops and local climatic conditions, this paper carries on regional division of tropical crops by fuzzy mathematics. Based on calculation of basic parameters for tl1e formation of production, near-tem optimum models of tropical crops structure of each region was established by means of multi-objective programming, and a far-term grey programming model was set up through the above-mentioned near-term model and prediction of future parameters. Conclusion shows that the near-term programming may raise the profit by 5. 1-55.7 percent and far-tem programming by 54-90 percent, both gainingobvious economic benefits.
文摘In this paper, a modified method to find the efficient solutions of multi-objective linear fractional programming (MOLFP) problems is presented. While some of the previously proposed methods provide only one efficient solution to the MOLFP problem, this modified method provides multiple efficient solutions to the problem. As a result, it provides the decision makers flexibility to choose a better option from alternatives according to their financial position and their level of satisfaction of objectives. A numerical example is provided to illustrate the modified method and also a real life oriented production problem is modeled and solved.
文摘This paper describes the object-oriented implementational method of finite element structural analysis, gives the basic concepts of the object-oriented method and objectoriented programming, develops a complete class hierarchy structure of object-oriented finite element structural analysis, and gives a part C+ + code description.