Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairments in the initial stage, which lead to severe cognitive dysfunction in the later stage. Action observation therapy (AOT) is...Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairments in the initial stage, which lead to severe cognitive dysfunction in the later stage. Action observation therapy (AOT) is a multisensory cognitive rehabilitation technique where the patient initially observes the actions and then tries to perform. The study aimed to examine the impact of AOT along with usual physiotherapy interventions to reduce depression, improve cognition and balance of a patient with AD. A 67 years old patient with AD was selected for this study because the patient has been suffering from depression, dementia, and physical dysfunction along with some other health conditions like diabetes and hypertension. Before starting intervention, a baseline assessment was done through the Beck Depression Inventory (BDI) tool, the Mini-Cog Scale, and the Berg Balance Scale (BBS). The patient received 12 sessions of AOT along with usual physiotherapy interventions thrice a week for four weeks, which included 45 minutes of each session. After four weeks of intervention, the patient demonstrated significant improvement in depression, cognition, and balance, whereas the BDI score declined from moderate 21/63 to mild 15/63 level of depression. The Mini-Cog score improved from 2/5 to 4/5, and the BBS score increased from 18/56 to 37/56. It is concluded that AOT along with usual physiotherapy intervention helps to reduce depression, improve cognition and balance of people with AD.展开更多
Limit theorems for non-additive probabilities or non-linear expectations are challenging issues which have attracted a lot of interest recently.The purpose of this paper is to study the strong law of large numbers and...Limit theorems for non-additive probabilities or non-linear expectations are challenging issues which have attracted a lot of interest recently.The purpose of this paper is to study the strong law of large numbers and the law of the iterated logarithm for a sequence of random variables in a sub-linear expectation space under a concept of extended independence which is much weaker and easier to verify than the independence proposed by Peng[20].We introduce a concept of extended negative dependence which is an extension of the kind of weak independence and the extended negative independence relative to classical probability that has appeared in the recent literature.Powerful tools such as moment inequality and Kolmogorov’s exponential inequality are established for these kinds of extended negatively independent random variables,and these tools improve a lot upon those of Chen,Chen and Ng[1].The strong law of large numbers and the law of iterated logarithm are also obtained by applying these inequalities.展开更多
Globally, mountains encompass spectacular landscapes and a great diversity of species. However, Savannah’s mountains in Sudan have been affected by the loss of diversity due to human activities and climate changes. T...Globally, mountains encompass spectacular landscapes and a great diversity of species. However, Savannah’s mountains in Sudan have been affected by the loss of diversity due to human activities and climate changes. Therefore, this study aims to assess changes in wildlife diversity in Jebel-Eldair Nation Park (JENP) based on only reports from patrolling activities, especially in the absence of regular wildlife monitoring programs. Reports of monthly wildlife observations during patrolling trips were used for the summer season in 2010 and 2018. Findings showed a moderate to high decline in the most important wildlife species (i.e. lion, wild dog, and crest porcupine). Six others are documented as rare species in reserve, including the civet, spotted hyena, striped hyena, jackal, seraval, and Siberian bird. Contrary and despite the diversity reduction, some species witnessed increases in their observation frequency, such as lesser kudu, caracal, monitor, and lunar bird. Moreover, human settlements, agricultural activities, and other anthropogenic factors were found to be the main drivers of biodiversity reduction in JENP. The study recommends adopting this method to detect changes in wildlife communities, especially in a situation of deficiency and lack of funding to conduct regular monitoring programs.展开更多
Security and reliability must be focused on control sys- tems firstly, and fault detection and diagnosis (FDD) is the main theory and technology. Now, there are many positive results in FDD for linear networked cont...Security and reliability must be focused on control sys- tems firstly, and fault detection and diagnosis (FDD) is the main theory and technology. Now, there are many positive results in FDD for linear networked control systems (LNCSs), but nonlinear networked control systems (NNCSs) are less involved. Based on the T-S fuzzy-modeling theory, NNCSs are modeled and network random time-delays are changed into the unknown bounded uncertain part without changing its structure. Then a fuzzy state observer is designed and an observer-based fault detection approach for an NNCS is presented. The main results are given and the relative theories are proved in detail. Finally, some simulation results are given and demonstrate the proposed method is effective.展开更多
China: the future of nuclear powerWang Yonggan: In terms of the highlighted issue ofenergy security, oil is of paramount importance, coal isthe foundation and electricity is the pivot according
The heads of state of China and the U.S. reached a consensus in Osaka at the end of June, agreeing to restart trade negotiations on the basis of equality and mutual respect. The U.S. side stated that it would no longe...The heads of state of China and the U.S. reached a consensus in Osaka at the end of June, agreeing to restart trade negotiations on the basis of equality and mutual respect. The U.S. side stated that it would no longer impose new tariffs on Chinese imports, sending a positive sign of the U.S.-China relationship to the international community. On July 3, the Washington Post published an open letter signed by 100 people from the academic, diplomatic, military, and business circles of the U.S. to President Trump and the U.S. Congress, affirming that the consensus is the intention of the two peoples and is in line with the expectations of the international community. The decline in U.S.- China relations is not in line with U.S. and global interests, and China is not an enemy of the U.S., nor does China pose a threat to U.S. national security.展开更多
An innate sensitivity to and phobia of China’s rise seem to have gripped someWestern observers for years.Early back in the 19th century,Napoleon warned the West to“let Chinasleep”.“There lies a sleeping giant,”be...An innate sensitivity to and phobia of China’s rise seem to have gripped someWestern observers for years.Early back in the 19th century,Napoleon warned the West to“let Chinasleep”.“There lies a sleeping giant,”begins his well-known remark.“Let hersleep.For when she wakes,she will shake the world.”In the 1990s,these展开更多
The rapid growth of IT industry in the information age has brought broad prospects to China and the world UESTC,an important research and innovation center of China,is now engaged in the implementation of the great st...The rapid growth of IT industry in the information age has brought broad prospects to China and the world UESTC,an important research and innovation center of China,is now engaged in the implementation of the great strategic plans of"Strengthening the military power with Science展开更多
Introduction:Alzheimer’s disease(AD)begins to develop decades prior to its clinical manifestation(Sperling et al.,2011),and while it is the most common form of dementia,as of yet there is no cure.Two of the most...Introduction:Alzheimer’s disease(AD)begins to develop decades prior to its clinical manifestation(Sperling et al.,2011),and while it is the most common form of dementia,as of yet there is no cure.Two of the most researched pathological features contributing to disease development are the extracellular amyloid plaques composed of amyloid-beta proteins(Aβ)and neurofibrillary tangles of tau proteins.Another feature of AD is the progression of early neuronal excitability/hyperactivity to silencing/hypoactivity(Palop and Mucke,2010),展开更多
Objective In order to reduce the interfering noise from the earth surface, scientists have carried out multi-geophysical borehole observations and the related study. This study aims at improving signal-to-noise ratio ...Objective In order to reduce the interfering noise from the earth surface, scientists have carried out multi-geophysical borehole observations and the related study. This study aims at improving signal-to-noise ratio obtained from the observation data to obtain zero noise data, which will be of great help to improve geophysical studies. Insights from this study will be significant for the earthquake disaster reduction, resource exploration and environmental protection.展开更多
Temperature (T) and salinity (S) profiles from conductivity-temperature-depth data collected during the Northern South China Sea Open Cruise from August 16 to September 13, 2008 are assimilated using Ensemble Kalm...Temperature (T) and salinity (S) profiles from conductivity-temperature-depth data collected during the Northern South China Sea Open Cruise from August 16 to September 13, 2008 are assimilated using Ensemble Kalman Filter (EnKF). An adaptive observational error strategy is used to prevent filter from diverging. In the meantime, aiming at the limited improvement in some sites caused by the T and S biases in the model, a T-S constraint scheme is adopted to improve the assimilation performance, where T and S are separately updated at these locations. Validation is performed by comparing assimilated outputs with independent in situ data (satellite remote sensing sea level anomaly (SLA), the OSCAR velocity product and shipboard ADCP). The results show that the new EnKF assimilation scheme can significantly reduce the root mean square error (RMSE) of oceanic T and S compared with the control run and traditional EnKF. The system can also improve the simulation of circulations and SLA.展开更多
文摘Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive impairments in the initial stage, which lead to severe cognitive dysfunction in the later stage. Action observation therapy (AOT) is a multisensory cognitive rehabilitation technique where the patient initially observes the actions and then tries to perform. The study aimed to examine the impact of AOT along with usual physiotherapy interventions to reduce depression, improve cognition and balance of a patient with AD. A 67 years old patient with AD was selected for this study because the patient has been suffering from depression, dementia, and physical dysfunction along with some other health conditions like diabetes and hypertension. Before starting intervention, a baseline assessment was done through the Beck Depression Inventory (BDI) tool, the Mini-Cog Scale, and the Berg Balance Scale (BBS). The patient received 12 sessions of AOT along with usual physiotherapy interventions thrice a week for four weeks, which included 45 minutes of each session. After four weeks of intervention, the patient demonstrated significant improvement in depression, cognition, and balance, whereas the BDI score declined from moderate 21/63 to mild 15/63 level of depression. The Mini-Cog score improved from 2/5 to 4/5, and the BBS score increased from 18/56 to 37/56. It is concluded that AOT along with usual physiotherapy intervention helps to reduce depression, improve cognition and balance of people with AD.
基金Research supported by grants from the NSF of China(1173101212031005)+2 种基金Ten Thousands Talents Plan of Zhejiang Province(2018R52042)NSF of Zhejiang Province(LZ21A010002)the Fundamental Research Funds for the Central Universities。
文摘Limit theorems for non-additive probabilities or non-linear expectations are challenging issues which have attracted a lot of interest recently.The purpose of this paper is to study the strong law of large numbers and the law of the iterated logarithm for a sequence of random variables in a sub-linear expectation space under a concept of extended independence which is much weaker and easier to verify than the independence proposed by Peng[20].We introduce a concept of extended negative dependence which is an extension of the kind of weak independence and the extended negative independence relative to classical probability that has appeared in the recent literature.Powerful tools such as moment inequality and Kolmogorov’s exponential inequality are established for these kinds of extended negatively independent random variables,and these tools improve a lot upon those of Chen,Chen and Ng[1].The strong law of large numbers and the law of iterated logarithm are also obtained by applying these inequalities.
文摘Globally, mountains encompass spectacular landscapes and a great diversity of species. However, Savannah’s mountains in Sudan have been affected by the loss of diversity due to human activities and climate changes. Therefore, this study aims to assess changes in wildlife diversity in Jebel-Eldair Nation Park (JENP) based on only reports from patrolling activities, especially in the absence of regular wildlife monitoring programs. Reports of monthly wildlife observations during patrolling trips were used for the summer season in 2010 and 2018. Findings showed a moderate to high decline in the most important wildlife species (i.e. lion, wild dog, and crest porcupine). Six others are documented as rare species in reserve, including the civet, spotted hyena, striped hyena, jackal, seraval, and Siberian bird. Contrary and despite the diversity reduction, some species witnessed increases in their observation frequency, such as lesser kudu, caracal, monitor, and lunar bird. Moreover, human settlements, agricultural activities, and other anthropogenic factors were found to be the main drivers of biodiversity reduction in JENP. The study recommends adopting this method to detect changes in wildlife communities, especially in a situation of deficiency and lack of funding to conduct regular monitoring programs.
文摘Security and reliability must be focused on control sys- tems firstly, and fault detection and diagnosis (FDD) is the main theory and technology. Now, there are many positive results in FDD for linear networked control systems (LNCSs), but nonlinear networked control systems (NNCSs) are less involved. Based on the T-S fuzzy-modeling theory, NNCSs are modeled and network random time-delays are changed into the unknown bounded uncertain part without changing its structure. Then a fuzzy state observer is designed and an observer-based fault detection approach for an NNCS is presented. The main results are given and the relative theories are proved in detail. Finally, some simulation results are given and demonstrate the proposed method is effective.
文摘China: the future of nuclear powerWang Yonggan: In terms of the highlighted issue ofenergy security, oil is of paramount importance, coal isthe foundation and electricity is the pivot according
文摘The heads of state of China and the U.S. reached a consensus in Osaka at the end of June, agreeing to restart trade negotiations on the basis of equality and mutual respect. The U.S. side stated that it would no longer impose new tariffs on Chinese imports, sending a positive sign of the U.S.-China relationship to the international community. On July 3, the Washington Post published an open letter signed by 100 people from the academic, diplomatic, military, and business circles of the U.S. to President Trump and the U.S. Congress, affirming that the consensus is the intention of the two peoples and is in line with the expectations of the international community. The decline in U.S.- China relations is not in line with U.S. and global interests, and China is not an enemy of the U.S., nor does China pose a threat to U.S. national security.
文摘An innate sensitivity to and phobia of China’s rise seem to have gripped someWestern observers for years.Early back in the 19th century,Napoleon warned the West to“let Chinasleep”.“There lies a sleeping giant,”begins his well-known remark.“Let hersleep.For when she wakes,she will shake the world.”In the 1990s,these
文摘The rapid growth of IT industry in the information age has brought broad prospects to China and the world UESTC,an important research and innovation center of China,is now engaged in the implementation of the great strategic plans of"Strengthening the military power with Science
文摘Introduction:Alzheimer’s disease(AD)begins to develop decades prior to its clinical manifestation(Sperling et al.,2011),and while it is the most common form of dementia,as of yet there is no cure.Two of the most researched pathological features contributing to disease development are the extracellular amyloid plaques composed of amyloid-beta proteins(Aβ)and neurofibrillary tangles of tau proteins.Another feature of AD is the progression of early neuronal excitability/hyperactivity to silencing/hypoactivity(Palop and Mucke,2010),
基金supported by the National Science Foundation of China (grant No.1374052)
文摘Objective In order to reduce the interfering noise from the earth surface, scientists have carried out multi-geophysical borehole observations and the related study. This study aims at improving signal-to-noise ratio obtained from the observation data to obtain zero noise data, which will be of great help to improve geophysical studies. Insights from this study will be significant for the earthquake disaster reduction, resource exploration and environmental protection.
基金The Strategic Priority Research Program of the Chinese Academy of Sciences under contract No.XDA10010405the Promgram of Guangdong Province Department of Science and Technology No.2012A032100004+1 种基金the National Natural Science Foundation of China under contract Nos 41476012,41521005 and 41406131the Knowledge Innovation Program of the Chinese Academy of Sciences under contract Nos SQ201001 and SQ201205
文摘Temperature (T) and salinity (S) profiles from conductivity-temperature-depth data collected during the Northern South China Sea Open Cruise from August 16 to September 13, 2008 are assimilated using Ensemble Kalman Filter (EnKF). An adaptive observational error strategy is used to prevent filter from diverging. In the meantime, aiming at the limited improvement in some sites caused by the T and S biases in the model, a T-S constraint scheme is adopted to improve the assimilation performance, where T and S are separately updated at these locations. Validation is performed by comparing assimilated outputs with independent in situ data (satellite remote sensing sea level anomaly (SLA), the OSCAR velocity product and shipboard ADCP). The results show that the new EnKF assimilation scheme can significantly reduce the root mean square error (RMSE) of oceanic T and S compared with the control run and traditional EnKF. The system can also improve the simulation of circulations and SLA.