Cognitive Behavioral Therapy:A Strategy for Depressive Moods Reduction of in Patients Experiencing Chronic Obstructive Pulmonary Emphysema Disease

Patients with Chronic Obstructive Pulmonary Disease(COPD)often experience difficulty breathing,decreased exercise tolerance and respiratory function as the disease progresses.Pulmonary rehabilitation training can improve respiratory symptoms,increase exercise tolerance and quality of life through exercise stimulation.However,after the end of pulmonary rehabilitation training,the patient's movement behavior is not easy to maintain.Cognitive behavioral therapy(CBT)can effectively enhance cognition,strengthen the motivation of"regular motor behavior",and maintain motor behavior,which can be used as a maintenance strategy for pulmonary rehabilitation training.Objective:To study the effect of cognitive behavioral therapy on the rehabilitation effect and the changing stage of"regular motor behavior"in COPD patients.Methods:30 patients consulted in the Rehabilitation Department of the Third Veterans Hospital of Sichuan Province were interviewed by telephone,and the exercise status and rehabilitation status were recorded and analyzed.From 30 patients,severe and extremely severe(GOLD grade III-IV)in motivation period of"regular exercise behavior"(not starting regular exercise but had exercise thoughts)were randomly divided into two groups.Pulmonary rehabilitation group(CBT-PR group,n=15)conducted one-to-one CBT intervention for 30-40 minutes to discuss the reasons for regular exercise and teach exercise precautions and principles using exercise education form;conventional pulmonary rehabilitation group(conventional PR group,n=15)conducted intensive pulmonary rehabilitation education without consultation and discussion.Both groups underwent 4 weeks of outpatient rehabilitation training,And the regular exercise ability was detected in the first and third months after training(6-Minutes Walking Distance,6-WMD;Short Physical Performance Battery,SPPB),(International Physical Activity Questionnaire,IPAQ),(St.George's Respiratory Scale,St.George's Respiratory Questionnaire,SGRQ),change.

Interleukin-6 in bronchoalveolar lavage fluid from patients with COPD

Objective To obtain new insights into the behavior of Interleukin-6(IL-6)in bronchoalveolar lavage fluid (BALF)and released from alveolar macrophages(AM)in chronic obstructive pulmonary diseases (COPD),and reveal the relationship between IL-6 and the development of emphysema in COPD.Methods IL-6 in BALF and released by AM in BALF were examined in 7 non-smoking subjects and 21 patients with COPD.According to the 95% confidence limits of IL-6 in BALF from non-smoking subjects,the patients were divided into two groups:those who were within the limits were assigned to the first group,and those who were above the limits were assigned to the second group.Results The concentration of IL-6 released by AM was much higher in the second group than in the first one.Between the two groups,significant differences were found in pulmonary function.Conclusion Our results suggest that the concentration of IL-6 released by AM may be related with pulmonary function,and IL-6 may play a role in the development of emphysema in patients with COPD.