An L(0,1)-labelling of a graph G is an assignment of nonnegative integers to the vertices of G such that the difference between the labels assigned to any two adjacent vertices is at least zero and the difference betw...An L(0,1)-labelling of a graph G is an assignment of nonnegative integers to the vertices of G such that the difference between the labels assigned to any two adjacent vertices is at least zero and the difference between the labels assigned to any two vertices which are at distance two is at least one. The span of an L(0,1)-labelling is the maximum label number assigned to any vertex of G. The L(0,1)-labelling number of a graph G, denoted by λ0.1(G) is the least integer k such that G has an L(0,1)-labelling of span k. This labelling has an application to a computer code assignment problem. The task is to assign integer control codes to a network of computer stations with distance restrictions. A cactus graph is a connected graph in which every block is either an edge or a cycle. In this paper, we label the vertices of a cactus graph by L(0,1)-labelling and have shown that, △-1≤λ0.1(G)≤△ for a cactus graph, where △ is the degree of the graph G.展开更多
Condense matter methods and mathematical models used in solving problems in solid state physics are transformed to high energy quantum cosmology in order to estimate the magnitude of the missing dark energy of the uni...Condense matter methods and mathematical models used in solving problems in solid state physics are transformed to high energy quantum cosmology in order to estimate the magnitude of the missing dark energy of the universe. Looking at the problem from this novel viewpoint was rewarded by a rather unexpected result, namely that the gap labelling method of integrated density of states for three dimensional icosahedral quasicrystals is identical to the previously measured and theoretically concluded ordinary energy density of the universe, namely a mere 4.5 percent of Einstein’s energy density, i.e. E(O) = mc2/22 where E is the energy, m is the mass and c is the speed of light. Consequently we conclude that the missing dark energy density must be E(D) = 1 - E(O) = mc2(21/22) in agreement with all known cosmological measurements and observations. This result could also be interpreted as a strong evidence for the self similarity of the geometry of spacetime, which is an expression of its basic fractal nature.展开更多
MULTIPLE sclerosis (MS) is a common inflammatory demyelinating disorder of central nervous system, and the disease burder could be well evaluated by conven-tional magnetic resonance imaging (MRI),1 including T2-we...MULTIPLE sclerosis (MS) is a common inflammatory demyelinating disorder of central nervous system, and the disease burder could be well evaluated by conven-tional magnetic resonance imaging (MRI),1 including T2-weighted, fluid-attenuatd inversion recovery, and postcontrast Tl-weighted sequences. 2 We investigated the perfusion state of MS plaques using brain perfusion imaging in a 12-year-old boy with MS.展开更多
Building up graph models to simulate scale-free networks is an important method since graphs have been used in researching scale-free networks. One use labelled graphs for distinguishing objects of communication and i...Building up graph models to simulate scale-free networks is an important method since graphs have been used in researching scale-free networks. One use labelled graphs for distinguishing objects of communication and information networks. In this paper some methods are given for constructing larger felicitous graphs from smaller graphs having special felicitous labellings, and some network models are shown to be felicitous.展开更多
In this study,the nitrogen removal performance of partial denitrificaiton/anammox(PDA)process was investigated by using an UASB reactor.High total nitrogen(TN)removal efficiency(91.97%)was achieved at an influent nitr...In this study,the nitrogen removal performance of partial denitrificaiton/anammox(PDA)process was investigated by using an UASB reactor.High total nitrogen(TN)removal efficiency(91.97%)was achieved at an influent nitrogen loading rate of 0.64 kg/(m3·d).Anammox bacteria did execute the function of converting nitrate to nitrite in PDA system according to ^(15)N isotope labeling experiments and the contribution was approximately 36.3%.Candidatus_Brocadia,Candidatus_Kuenenia and Thauera were functional strains for anammox and denitrification process,respectively.Thauera and Candidatus_Brocadia were more important for TN removal at high loading rates(0.64 kg/(m3·d)).This result can provide a theoretical and technical foundation for the application of the PDA process.展开更多
This paper described the ~3H NMR determination of the positions and content of 24 tritium labeled aromatic and heterocyclic compounds prepared by catalytic tritiation derivatives, pyrrole, 1,2,4-triazole, thiazole, be...This paper described the ~3H NMR determination of the positions and content of 24 tritium labeled aromatic and heterocyclic compounds prepared by catalytic tritiation derivatives, pyrrole, 1,2,4-triazole, thiazole, benzothiazole, purine and derivatives, indole, indanol, piperidine and derivative, diphenylamine, N- phenylanthranilic acid, 8- OH- quinoline, naphthol, diphenylether have been tritiated by catalytic exchange method using tritiated water and platinum catalyst (from the dioxide and sodium borohydride), and the pattern of labelling has been assigned by ~3H NMR spectroscopy. The results show that this exchange process can give general labelling compounds at various time and temperatures. For 4-Br-diphenylether, Raney nickel was used instead of Pt as a catalyst.展开更多
This paper shows that, for every unit interval graph, there is a labelling which is simultaneously optimal for the following seven graph labelling problems: bandwidth, cyclic bandwidth, profile, fill-in, cutwidth, mod...This paper shows that, for every unit interval graph, there is a labelling which is simultaneously optimal for the following seven graph labelling problems: bandwidth, cyclic bandwidth, profile, fill-in, cutwidth, modified cutwidth, and bandwidth sum(linear arrangement).展开更多
Objective To study the relationship between apoptosis and hypertrophy of the left ventricie (LV) before and after its regression with antihypertensive treatment. Methods Forty 12- week old spontaneously. hypertensive ...Objective To study the relationship between apoptosis and hypertrophy of the left ventricie (LV) before and after its regression with antihypertensive treatment. Methods Forty 12- week old spontaneously. hypertensive rats(SHR were randomly divided into 2 groups, one given enalapril (SHR - d grouP) and the other without treatment (SHR group). Twenty normotensive Wistar Kyoto rats of the same age served as controls (WKY group). The changes of body weight and blood pressure were observed for 3 months. The rats were killed at the 24th week of age. The weight of LV, the body weight (B W), and the ratio of LV/BW were compared between the groups. Then by in situ specific labelling of nuclear DNA fragmentation, the apoptosis in the wall of the left ventricle was compared between them. RcsuIts The index of apoptosis was SHR - d>SHR> WKY The dofference was significant. ConcIusion The hypertrophy of the LV and its regression is very’likely related with the imbalance between the proloferation and death of cells of the muscle in the LV.展开更多
The design of large disk array architectures leads to interesting combinatorial problems. Minimizing the number of disk operations when writing to consecutive disks leads to the concept of “cluttered orderings” whic...The design of large disk array architectures leads to interesting combinatorial problems. Minimizing the number of disk operations when writing to consecutive disks leads to the concept of “cluttered orderings” which were introduced for the complete graph by Cohen et al. (2001). Mueller et al. (2005) adapted the concept of wrapped Δ-labellings to the complete bipartite case. In this paper, we give some sequence in order to generate wrapped Δ-labellings as cluttered orderings for the complete bipartite graph. New sequence we give is different from the sequences Mueller et al. gave, though the same graphs in which these sequences are labeled.展开更多
The need to inform consumers about the health impact of their food choices is ever more pressing in a world where obesity is a growing problem. Concerns over food safety, its origins and its environmental impacts are ...The need to inform consumers about the health impact of their food choices is ever more pressing in a world where obesity is a growing problem. Concerns over food safety, its origins and its environmental impacts are also growing, as frequently reported in the popular press in many parts of the world. Nutritional and health information on food labels is quite well developed, but the complex nature of the information presented may hinder widespread use of the existing labels. In comparison, there has been little widespread success of carbon labels on food, and their usefulness in reducing carbon emissions from consumption is uncertain. In an attempt to address the need for clearer information on health and environmental impacts of food purchases, we present a novel dual-purpose food labelling system which provides information on both health and environmental impacts of food items. This paper presents results from a pilot study introducing a novel approach to food labelling: a simplified, combined carbon and health label to inform consumers simultaneously about the environmental and health impacts of their choices. Environmental impacts of various food categories were calculated on the basis of their relative energy use along the supply chain by using a newly designed Food Energy Index. Health impacts were based on the NuVal system developed in the USA in 2010. As part of the Norfolk Island Carbon and Health Evaluation study (NICHE), labels were designed, tested and displayed on 25 food categories for a 3-month period in the main supermarket on Norfolk Island (Australia). The in-store labelling trial was followed by a consumer survey on their attitudes to the labels. The results from this pilot trial indicate that consumers were supportive of food labelling including both environmental and health impacts, but the information provided in the dual labels was not sufficient to induce changes in consumption between food categories. We conclude that simple label design is clearly essential, and our findings warrant further investigation, including a broader study using a larger population and a wider range of food categories.展开更多
The labelling and imaging of tumor cells were investigated via arginine-glycine-aspartic acidcysteine(RGDC) peptide-labelled quantum dots(QDs). The results show that RGDC modified QDs can label SMMC-7721 tumor cel...The labelling and imaging of tumor cells were investigated via arginine-glycine-aspartic acidcysteine(RGDC) peptide-labelled quantum dots(QDs). The results show that RGDC modified QDs can label SMMC-7721 tumor cells and adhere to cellular membrane. In constrast, the unmodified QDs are mainly dispersed around the cell. We also found that the RGDC-QDs can penetrate into the cell at 2 h of incubation. After 6 h of incubation, RGDC-QDs can accumulate in a unique intracellular region.展开更多
Correct drug labelling is central for ensuring proper drug dispensing and thus for patient safety. Labelling errors may result in adverse health outcomes. The objective of this study was, therefore, to assess the effe...Correct drug labelling is central for ensuring proper drug dispensing and thus for patient safety. Labelling errors may result in adverse health outcomes. The objective of this study was, therefore, to assess the effect of labelling on the quality of drug dispensing and patient knowledge about dispensed drugs in Jimma University model and specialized hospital outpatient Pharmacies. Individual packages with prescribed drugs were examined using pretested questionnaire and observational check lists during the dispensing process. Patients’ knowledge about drugs dispensed to them was assessed at the exit interview using a pretested questionnaire. Out of 743 prescribed drugs, 682 (91.8%) were dispensed to 426 patients. The average labelling score (range from 0 to 6) of dispensed drugs in Model and Outpatient pharmacy was 2.00 (95% CI 1.97 to 2.04) and 1.73 (95% CI 1.6 to 1.8) respectively, with overall average labelling score of 1.90 (95% CI 1.84 to 1.91). The average patient knowledge score (range from 0 t0 5) was 3.45 (95% CI 3.31 to 3.59) and 3.5 (95% CI 3.35 to 3.64) for model and outpatient pharmacy, respectively, while the overall average knowledge score was 3.46 (95% CI 3.37 to 3.57). Major labelling problems were absence of patient’s name and dose followed by frequency of administration, duration of treatment, and the reason for prescription. Literacy status of patients had a significant effect on their knowledge (p 0.05). We recommend that corrective measures targeting both, labelling and patients’ knowledge should be implemented to improve the patients’ safety and drug therapy adherence.展开更多
A recently discovered approach including de Brujin graphs and Eulerian circuits are used to DNA sequencing and fragment assembly, and to simplify DNA graphs through a series of transformations on graphs and digraphs i...A recently discovered approach including de Brujin graphs and Eulerian circuits are used to DNA sequencing and fragment assembly, and to simplify DNA graphs through a series of transformations on graphs and digraphs in the field of bioinformatics. Since numbered graphs provide underlying mathematical models in studying the wide variety of seemingly unrelated practical applications, so graph colorings often are used to divide large systems into subsystems. A new graph labeling has been introduced and investigated.展开更多
Automated labelling of radiology reports using natural language processing allows for the labelling of ground truth for large datasets of radiological studies that are required for training of computer vision models.T...Automated labelling of radiology reports using natural language processing allows for the labelling of ground truth for large datasets of radiological studies that are required for training of computer vision models.This paper explains the necessary data preprocessing steps,reviews the main methods for automated labelling and compares their performance.There are four main methods of automated labelling,namely:(1)rules-based text-matching algorithms,(2)conventional machine learning models,(3)neural network models and(4)Bidirectional Encoder Representations from Transformers(BERT)models.Rules-based labellers perform a brute force search against manually curated keywords and are able to achieve high F1 scores.However,they require proper handling of negative words.Machine learning models require preprocessing that involves tokenization and vectorization of text into numerical vectors.Multilabel classification approaches are required in labelling radiology reports and conventional models can achieve good performance if they have large enough training sets.Deep learning models make use of connected neural networks,often a long short-term memory network,and are similarly able to achieve good performance if trained on a large data set.BERT is a transformer-based model that utilizes attention.Pretrained BERT models only require fine-tuning with small data sets.In particular,domain-specific BERT models can achieve superior performance compared with the other methods for automated labelling.展开更多
The success of deep transfer learning in fault diagnosis is attributed to the collection of high-quality labeled data from the source domain.However,in engineering scenarios,achieving such high-quality label annotatio...The success of deep transfer learning in fault diagnosis is attributed to the collection of high-quality labeled data from the source domain.However,in engineering scenarios,achieving such high-quality label annotation is difficult and expensive.The incorrect label annotation produces two negative effects:1)the complex decision boundary of diagnosis models lowers the generalization performance on the target domain,and2)the distribution of target domain samples becomes misaligned with the false-labeled samples.To overcome these negative effects,this article proposes a solution called the label recovery and trajectory designable network(LRTDN).LRTDN consists of three parts.First,a residual network with dual classifiers is to learn features from cross-domain samples.Second,an annotation check module is constructed to generate a label anomaly indicator that could modify the abnormal labels of false-labeled samples in the source domain.With the training of relabeled samples,the complexity of diagnosis model is reduced via semi-supervised learning.Third,the adaptation trajectories are designed for sample distributions across domains.This ensures that the target domain samples are only adapted with the pure-labeled samples.The LRTDN is verified by two case studies,in which the diagnosis knowledge of bearings is transferred across different working conditions as well as different yet related machines.The results show that LRTDN offers a high diagnosis accuracy even in the presence of incorrect annotation.展开更多
The Internet revolution has resulted in abundant data from various sources,including social media,traditional media,etcetera.Although the availability of data is no longer an issue,data labelling for exploiting it in ...The Internet revolution has resulted in abundant data from various sources,including social media,traditional media,etcetera.Although the availability of data is no longer an issue,data labelling for exploiting it in supervised machine learning is still an expensive process and involves tedious human efforts.The overall purpose of this study is to propose a strategy to automatically label the unlabeled textual data with the support of active learning in combination with deep learning.More specifically,this study assesses the performance of different active learning strategies in automatic labelling of the textual dataset at sentence and document levels.To achieve this objective,different experiments have been performed on the publicly available dataset.In first set of experiments,we randomly choose a subset of instances from training dataset and train a deep neural network to assess performance on test set.In the second set of experiments,we replace the random selection with different active learning strategies to choose a subset of the training dataset to train the same model and reassess its performance on test set.The experimental results suggest that different active learning strategies yield performance improvement of 7% on document level datasets and 3%on sentence level datasets for auto labelling.展开更多
Having as a starting point of the problematic energy consumption of buildings, it studied the panorama of energy efficiency, emphasizing the Brazilian program of the INMETRO (Instituto Nacional de Metrologia, Normali...Having as a starting point of the problematic energy consumption of buildings, it studied the panorama of energy efficiency, emphasizing the Brazilian program of the INMETRO (Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial), PROCEL “Edifica” (national program for energy efficiency in buildings), contained in the norm RTQ-C (technical requirements of the quality for the level of energetic efficiency of commercial, service, and public buildings). For a better understanding of the regulation, it elected a building, emblematic in the city of Passo Fundo, RS, Brazil, illustrating the perspective of the program. The building was classified in accordance with the two methodologies presented by the program: prescriptive and simulation, so it was possible to investigate the peculiarities of each methodology and the own regulation. After the application of the methodologies, we came to the conclusion that the prescriptive method is less accurate and requires more dedication by the evaluator to do all the calculations and surveys required, however, it is the fastest tool and accessible to the field professionals. The simulation on the other hand, is a more accurate methodology and reaches levels of analysis that the prescriptive method does not reach, but still is a tool that needs large initial financial contribution and prior knowledge.展开更多
The aim of the research was to examine ewe and goat cheese labelling on the market of the Republic of Croatia. During the four years (2012-2016) of the research, 133 cheeses from retail supermarket chains were selecte...The aim of the research was to examine ewe and goat cheese labelling on the market of the Republic of Croatia. During the four years (2012-2016) of the research, 133 cheeses from retail supermarket chains were selected by the random-choice method by the responsible inspection of the Republic of Croatia and analysed at the Reference Laboratory for Milk and Dairy Products of the Department of Dairy Science at the Faculty of Agriculture University of Zagreb. To check the correct labelling of cheeses, the chemical composition of cheese was examined: the fat content, the dry matter content, the fat in dry matter content, and the water content in the fat-free cheese compound were calculated according to the Ordinance on Cheeses and Cheese Products, which refers to cheeses manufactured in the Republic of Croatia, and Regulation EU (2011) of the European Parliament and the Council on providing information to consumers about food products, which covers foreign cheeses. The presence of cow milk in cheeses labelled as products manufactured exclusively from ewe or goat milk was tested by the reference method using iso-electric focusing to determine any adulteration according to Commission Regulation (2008). The results of analysis in this research show the condition of the quality and correct labelling of ewe and goat cheeses on the market of the Republic of Croatia. Of the 133 cheeses analysed, 67 cheeses (50%) did not correspond to the values stated on the declaration or to legal regulations, while the presence of cow milk was found in 30% of the cheeses analysed. The research results indicate the need to carry out continuous systematic control in the interest of protecting consumers and those manufacturers who are following good manufacturing practices.展开更多
基金National Natural Science Foundation of China(No.10671074 and No.60673048)Natural Science Foundation of Education Ministry of Anhui Province(No.KJ2007B124 and No.2006KJ256B)
文摘An L(0,1)-labelling of a graph G is an assignment of nonnegative integers to the vertices of G such that the difference between the labels assigned to any two adjacent vertices is at least zero and the difference between the labels assigned to any two vertices which are at distance two is at least one. The span of an L(0,1)-labelling is the maximum label number assigned to any vertex of G. The L(0,1)-labelling number of a graph G, denoted by λ0.1(G) is the least integer k such that G has an L(0,1)-labelling of span k. This labelling has an application to a computer code assignment problem. The task is to assign integer control codes to a network of computer stations with distance restrictions. A cactus graph is a connected graph in which every block is either an edge or a cycle. In this paper, we label the vertices of a cactus graph by L(0,1)-labelling and have shown that, △-1≤λ0.1(G)≤△ for a cactus graph, where △ is the degree of the graph G.
文摘Condense matter methods and mathematical models used in solving problems in solid state physics are transformed to high energy quantum cosmology in order to estimate the magnitude of the missing dark energy of the universe. Looking at the problem from this novel viewpoint was rewarded by a rather unexpected result, namely that the gap labelling method of integrated density of states for three dimensional icosahedral quasicrystals is identical to the previously measured and theoretically concluded ordinary energy density of the universe, namely a mere 4.5 percent of Einstein’s energy density, i.e. E(O) = mc2/22 where E is the energy, m is the mass and c is the speed of light. Consequently we conclude that the missing dark energy density must be E(D) = 1 - E(O) = mc2(21/22) in agreement with all known cosmological measurements and observations. This result could also be interpreted as a strong evidence for the self similarity of the geometry of spacetime, which is an expression of its basic fractal nature.
文摘MULTIPLE sclerosis (MS) is a common inflammatory demyelinating disorder of central nervous system, and the disease burder could be well evaluated by conven-tional magnetic resonance imaging (MRI),1 including T2-weighted, fluid-attenuatd inversion recovery, and postcontrast Tl-weighted sequences. 2 We investigated the perfusion state of MS plaques using brain perfusion imaging in a 12-year-old boy with MS.
文摘Building up graph models to simulate scale-free networks is an important method since graphs have been used in researching scale-free networks. One use labelled graphs for distinguishing objects of communication and information networks. In this paper some methods are given for constructing larger felicitous graphs from smaller graphs having special felicitous labellings, and some network models are shown to be felicitous.
基金supported by the Natural Science Foundation of Shandong Province (ZR2019MEE038)the Fundamental Research Funds for the Central Universities (19CX02038A)the Key R&D Program of Shandong Province (Major Scientific and Technological Innovation Project 2019JZZY020502)
文摘In this study,the nitrogen removal performance of partial denitrificaiton/anammox(PDA)process was investigated by using an UASB reactor.High total nitrogen(TN)removal efficiency(91.97%)was achieved at an influent nitrogen loading rate of 0.64 kg/(m3·d).Anammox bacteria did execute the function of converting nitrate to nitrite in PDA system according to ^(15)N isotope labeling experiments and the contribution was approximately 36.3%.Candidatus_Brocadia,Candidatus_Kuenenia and Thauera were functional strains for anammox and denitrification process,respectively.Thauera and Candidatus_Brocadia were more important for TN removal at high loading rates(0.64 kg/(m3·d)).This result can provide a theoretical and technical foundation for the application of the PDA process.
文摘This paper described the ~3H NMR determination of the positions and content of 24 tritium labeled aromatic and heterocyclic compounds prepared by catalytic tritiation derivatives, pyrrole, 1,2,4-triazole, thiazole, benzothiazole, purine and derivatives, indole, indanol, piperidine and derivative, diphenylamine, N- phenylanthranilic acid, 8- OH- quinoline, naphthol, diphenylether have been tritiated by catalytic exchange method using tritiated water and platinum catalyst (from the dioxide and sodium borohydride), and the pattern of labelling has been assigned by ~3H NMR spectroscopy. The results show that this exchange process can give general labelling compounds at various time and temperatures. For 4-Br-diphenylether, Raney nickel was used instead of Pt as a catalyst.
文摘This paper shows that, for every unit interval graph, there is a labelling which is simultaneously optimal for the following seven graph labelling problems: bandwidth, cyclic bandwidth, profile, fill-in, cutwidth, modified cutwidth, and bandwidth sum(linear arrangement).
文摘Objective To study the relationship between apoptosis and hypertrophy of the left ventricie (LV) before and after its regression with antihypertensive treatment. Methods Forty 12- week old spontaneously. hypertensive rats(SHR were randomly divided into 2 groups, one given enalapril (SHR - d grouP) and the other without treatment (SHR group). Twenty normotensive Wistar Kyoto rats of the same age served as controls (WKY group). The changes of body weight and blood pressure were observed for 3 months. The rats were killed at the 24th week of age. The weight of LV, the body weight (B W), and the ratio of LV/BW were compared between the groups. Then by in situ specific labelling of nuclear DNA fragmentation, the apoptosis in the wall of the left ventricle was compared between them. RcsuIts The index of apoptosis was SHR - d>SHR> WKY The dofference was significant. ConcIusion The hypertrophy of the LV and its regression is very’likely related with the imbalance between the proloferation and death of cells of the muscle in the LV.
文摘The design of large disk array architectures leads to interesting combinatorial problems. Minimizing the number of disk operations when writing to consecutive disks leads to the concept of “cluttered orderings” which were introduced for the complete graph by Cohen et al. (2001). Mueller et al. (2005) adapted the concept of wrapped Δ-labellings to the complete bipartite case. In this paper, we give some sequence in order to generate wrapped Δ-labellings as cluttered orderings for the complete bipartite graph. New sequence we give is different from the sequences Mueller et al. gave, though the same graphs in which these sequences are labeled.
文摘The need to inform consumers about the health impact of their food choices is ever more pressing in a world where obesity is a growing problem. Concerns over food safety, its origins and its environmental impacts are also growing, as frequently reported in the popular press in many parts of the world. Nutritional and health information on food labels is quite well developed, but the complex nature of the information presented may hinder widespread use of the existing labels. In comparison, there has been little widespread success of carbon labels on food, and their usefulness in reducing carbon emissions from consumption is uncertain. In an attempt to address the need for clearer information on health and environmental impacts of food purchases, we present a novel dual-purpose food labelling system which provides information on both health and environmental impacts of food items. This paper presents results from a pilot study introducing a novel approach to food labelling: a simplified, combined carbon and health label to inform consumers simultaneously about the environmental and health impacts of their choices. Environmental impacts of various food categories were calculated on the basis of their relative energy use along the supply chain by using a newly designed Food Energy Index. Health impacts were based on the NuVal system developed in the USA in 2010. As part of the Norfolk Island Carbon and Health Evaluation study (NICHE), labels were designed, tested and displayed on 25 food categories for a 3-month period in the main supermarket on Norfolk Island (Australia). The in-store labelling trial was followed by a consumer survey on their attitudes to the labels. The results from this pilot trial indicate that consumers were supportive of food labelling including both environmental and health impacts, but the information provided in the dual labels was not sufficient to induce changes in consumption between food categories. We conclude that simple label design is clearly essential, and our findings warrant further investigation, including a broader study using a larger population and a wider range of food categories.
基金Supported by the National Natural Science Foundation of China(Nos.30970719, 21043002)the Social Development Project of Science and Technology Department of Jilin Province, China(Nos.20106031, 20090133)+1 种基金the Project of Science and Technology Department of Changchun City, China(No.09SF02)the Fundamental Research Funds of Jilin University, China (No.200903098)
文摘The labelling and imaging of tumor cells were investigated via arginine-glycine-aspartic acidcysteine(RGDC) peptide-labelled quantum dots(QDs). The results show that RGDC modified QDs can label SMMC-7721 tumor cells and adhere to cellular membrane. In constrast, the unmodified QDs are mainly dispersed around the cell. We also found that the RGDC-QDs can penetrate into the cell at 2 h of incubation. After 6 h of incubation, RGDC-QDs can accumulate in a unique intracellular region.
文摘Correct drug labelling is central for ensuring proper drug dispensing and thus for patient safety. Labelling errors may result in adverse health outcomes. The objective of this study was, therefore, to assess the effect of labelling on the quality of drug dispensing and patient knowledge about dispensed drugs in Jimma University model and specialized hospital outpatient Pharmacies. Individual packages with prescribed drugs were examined using pretested questionnaire and observational check lists during the dispensing process. Patients’ knowledge about drugs dispensed to them was assessed at the exit interview using a pretested questionnaire. Out of 743 prescribed drugs, 682 (91.8%) were dispensed to 426 patients. The average labelling score (range from 0 to 6) of dispensed drugs in Model and Outpatient pharmacy was 2.00 (95% CI 1.97 to 2.04) and 1.73 (95% CI 1.6 to 1.8) respectively, with overall average labelling score of 1.90 (95% CI 1.84 to 1.91). The average patient knowledge score (range from 0 t0 5) was 3.45 (95% CI 3.31 to 3.59) and 3.5 (95% CI 3.35 to 3.64) for model and outpatient pharmacy, respectively, while the overall average knowledge score was 3.46 (95% CI 3.37 to 3.57). Major labelling problems were absence of patient’s name and dose followed by frequency of administration, duration of treatment, and the reason for prescription. Literacy status of patients had a significant effect on their knowledge (p 0.05). We recommend that corrective measures targeting both, labelling and patients’ knowledge should be implemented to improve the patients’ safety and drug therapy adherence.
文摘A recently discovered approach including de Brujin graphs and Eulerian circuits are used to DNA sequencing and fragment assembly, and to simplify DNA graphs through a series of transformations on graphs and digraphs in the field of bioinformatics. Since numbered graphs provide underlying mathematical models in studying the wide variety of seemingly unrelated practical applications, so graph colorings often are used to divide large systems into subsystems. A new graph labeling has been introduced and investigated.
文摘Automated labelling of radiology reports using natural language processing allows for the labelling of ground truth for large datasets of radiological studies that are required for training of computer vision models.This paper explains the necessary data preprocessing steps,reviews the main methods for automated labelling and compares their performance.There are four main methods of automated labelling,namely:(1)rules-based text-matching algorithms,(2)conventional machine learning models,(3)neural network models and(4)Bidirectional Encoder Representations from Transformers(BERT)models.Rules-based labellers perform a brute force search against manually curated keywords and are able to achieve high F1 scores.However,they require proper handling of negative words.Machine learning models require preprocessing that involves tokenization and vectorization of text into numerical vectors.Multilabel classification approaches are required in labelling radiology reports and conventional models can achieve good performance if they have large enough training sets.Deep learning models make use of connected neural networks,often a long short-term memory network,and are similarly able to achieve good performance if trained on a large data set.BERT is a transformer-based model that utilizes attention.Pretrained BERT models only require fine-tuning with small data sets.In particular,domain-specific BERT models can achieve superior performance compared with the other methods for automated labelling.
基金the National Key R&D Program of China(2022YFB3402100)the National Science Fund for Distinguished Young Scholars of China(52025056)+4 种基金the National Natural Science Foundation of China(52305129)the China Postdoctoral Science Foundation(2023M732789)the China Postdoctoral Innovative Talents Support Program(BX20230290)the Open Foundation of Hunan Provincial Key Laboratory of Health Maintenance for Mechanical Equipment(2022JXKF JJ01)the Fundamental Research Funds for Central Universities。
文摘The success of deep transfer learning in fault diagnosis is attributed to the collection of high-quality labeled data from the source domain.However,in engineering scenarios,achieving such high-quality label annotation is difficult and expensive.The incorrect label annotation produces two negative effects:1)the complex decision boundary of diagnosis models lowers the generalization performance on the target domain,and2)the distribution of target domain samples becomes misaligned with the false-labeled samples.To overcome these negative effects,this article proposes a solution called the label recovery and trajectory designable network(LRTDN).LRTDN consists of three parts.First,a residual network with dual classifiers is to learn features from cross-domain samples.Second,an annotation check module is constructed to generate a label anomaly indicator that could modify the abnormal labels of false-labeled samples in the source domain.With the training of relabeled samples,the complexity of diagnosis model is reduced via semi-supervised learning.Third,the adaptation trajectories are designed for sample distributions across domains.This ensures that the target domain samples are only adapted with the pure-labeled samples.The LRTDN is verified by two case studies,in which the diagnosis knowledge of bearings is transferred across different working conditions as well as different yet related machines.The results show that LRTDN offers a high diagnosis accuracy even in the presence of incorrect annotation.
基金the Deanship of Scientific Research at Shaqra University for supporting this work.
文摘The Internet revolution has resulted in abundant data from various sources,including social media,traditional media,etcetera.Although the availability of data is no longer an issue,data labelling for exploiting it in supervised machine learning is still an expensive process and involves tedious human efforts.The overall purpose of this study is to propose a strategy to automatically label the unlabeled textual data with the support of active learning in combination with deep learning.More specifically,this study assesses the performance of different active learning strategies in automatic labelling of the textual dataset at sentence and document levels.To achieve this objective,different experiments have been performed on the publicly available dataset.In first set of experiments,we randomly choose a subset of instances from training dataset and train a deep neural network to assess performance on test set.In the second set of experiments,we replace the random selection with different active learning strategies to choose a subset of the training dataset to train the same model and reassess its performance on test set.The experimental results suggest that different active learning strategies yield performance improvement of 7% on document level datasets and 3%on sentence level datasets for auto labelling.
文摘Having as a starting point of the problematic energy consumption of buildings, it studied the panorama of energy efficiency, emphasizing the Brazilian program of the INMETRO (Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial), PROCEL “Edifica” (national program for energy efficiency in buildings), contained in the norm RTQ-C (technical requirements of the quality for the level of energetic efficiency of commercial, service, and public buildings). For a better understanding of the regulation, it elected a building, emblematic in the city of Passo Fundo, RS, Brazil, illustrating the perspective of the program. The building was classified in accordance with the two methodologies presented by the program: prescriptive and simulation, so it was possible to investigate the peculiarities of each methodology and the own regulation. After the application of the methodologies, we came to the conclusion that the prescriptive method is less accurate and requires more dedication by the evaluator to do all the calculations and surveys required, however, it is the fastest tool and accessible to the field professionals. The simulation on the other hand, is a more accurate methodology and reaches levels of analysis that the prescriptive method does not reach, but still is a tool that needs large initial financial contribution and prior knowledge.
基金part of the research project entitled“Quality control of cheeses on the market aimed at increasing competitiveness”financed by the Ministry of Agriculture,Agricultural Research Council(Project No.2012-11-27)acknowledge for supplying cheese samples and for financially support to the Ministry of Agriculture of Republic of Croatia.
文摘The aim of the research was to examine ewe and goat cheese labelling on the market of the Republic of Croatia. During the four years (2012-2016) of the research, 133 cheeses from retail supermarket chains were selected by the random-choice method by the responsible inspection of the Republic of Croatia and analysed at the Reference Laboratory for Milk and Dairy Products of the Department of Dairy Science at the Faculty of Agriculture University of Zagreb. To check the correct labelling of cheeses, the chemical composition of cheese was examined: the fat content, the dry matter content, the fat in dry matter content, and the water content in the fat-free cheese compound were calculated according to the Ordinance on Cheeses and Cheese Products, which refers to cheeses manufactured in the Republic of Croatia, and Regulation EU (2011) of the European Parliament and the Council on providing information to consumers about food products, which covers foreign cheeses. The presence of cow milk in cheeses labelled as products manufactured exclusively from ewe or goat milk was tested by the reference method using iso-electric focusing to determine any adulteration according to Commission Regulation (2008). The results of analysis in this research show the condition of the quality and correct labelling of ewe and goat cheeses on the market of the Republic of Croatia. Of the 133 cheeses analysed, 67 cheeses (50%) did not correspond to the values stated on the declaration or to legal regulations, while the presence of cow milk was found in 30% of the cheeses analysed. The research results indicate the need to carry out continuous systematic control in the interest of protecting consumers and those manufacturers who are following good manufacturing practices.