Image Motion Compensation of Off-Axis TMA Three-Line ArrayAerospace Mapping Cameras

To enhance the image motion compensation accuracy of off-axis three-mirror anastigmatic( TMA)three-line array aerospace mapping cameras,a new method of image motion velocity field modeling is proposed in this paper. Firstly,based on the imaging principle of mapping cameras,an analytical expression of image motion velocity of off-axis TMA three-line array aerospace mapping cameras is deduced from different coordinate systems we established and the attitude dynamics principle. Then,the case of a three-line array mapping camera is studied,in which the simulation of the focal plane image motion velocity fields of the forward-view camera,the nadir-view camera and the backward-view camera are carried out,and the optimization schemes for image motion velocity matching and drift angle matching are formulated according the simulation results. Finally,this method is verified with a dynamic imaging experimental system. The results are indicative of that when image motion compensation for nadir-view camera is conducted using the proposed image motion velocity field model,the line pair of target images at Nyquist frequency is clear and distinguishable. Under the constraint that modulation transfer function( MTF) reduces by 5%,when the horizontal frequencies of the forward-view camera and the backward-view camera are adjusted uniformly according to the proposed image motion velocity matching scheme,the time delay integration( TDI) stages reach 6 at most. When the TDI stages are more than 6,the three groups of camera will independently undergo horizontal frequency adjustment. However, when the proposed drift angle matching scheme is adopted for uniform drift angle adjustment,the number of TDI stages will not exceed 81. The experimental results have demonstrated the validity and accuracy of the proposed image motion velocity field model and matching optimization scheme,providing reliable basis for on-orbit image motion compensation of aerospace mapping cameras.

Optimization-based mode selection scheme for OAM millimeter wave system in the off-axis misalignment case

Millimeter-wave transmission combined with Orbital Angular Momentum(OAM)has the advantage of reducing the loss of beam power and increasing the system capacity.However,to fulfill this advantage,the antennas at the transmitter and receiver must be parallel and coaxial;otherwise,the accuracy of mode detection at the receiver can be seriously influenced.In this paper,we design an OAM millimeter-wave communication system for overcoming the above limitation.Specifically,the first contribution is that the power distribution between different OAM modes and the capacity of the system with different mode sets are analytically derived for performance analysis.The second contribution lies in that a novel mode selection scheme is proposed to reduce the total interference between different modes.Numerical results show that system performance is less affected by the offset when the mode set with smaller modes or larger intervals is selected.

Collision off-axis position dependence of relativistic nonlinear Thomson inverse scattering of an excited electron in a tightly focused circular polarized laser pulse

This paper presents a novel view of the impact of electron collision off-axis positions on the dynamic properties and relativistic nonlinear Thomson inverse scattering of excited electrons within tightly focused, circularly polarized laser pulses of varying intensities. We examine the effects of the transverse ponderomotive force, specifically how the deviation angle and speed of electron motion are affected by the initial off-axis position of the electron and the peak amplitude of the laser pulse. When the laser pulse intensity is low, an increase in the electron's initial off-axis distance results in reduced spatial radiation power, improved collimation, super-continuum phenomena generation, red-shifting of the spectrum's harmonic peak, and significant symmetry in the radiation radial direction. However, in contradiction to conventional understandings,when the laser pulse intensity is relatively high, the properties of the relativistic nonlinear Thomson inverse scattering of the electron deviate from the central axis, changing direction in opposition to the aforementioned effects. After reaching a peak, these properties then shift again, aligning with the previous direction. The complex interplay of these effects suggests a greater nuance and intricacy in the relationship between laser pulse intensity, electron position, and scattering properties than previously thought.

异氟烷麻醉对小鼠自发肌电及TUS/TMAS诱发肌电的影响

经颅超声刺激(TUS)和经颅磁声耦合刺激(TMAS)调控运动皮层效果明显,但受限于清醒状态动物难以束缚,已有研究大多在麻醉状态下进行,对麻醉减弱调控效果的分析集中于中枢神经系统。本研究记录了异氟烷麻醉下24只小鼠的肢体自发肌电和TUS/TMAS诱发肌电,定量分析了麻醉对自发肌电和诱发肌电发放率、潜伏期、时长和幅值的影响。结果显示,随着异氟烷输出浓度从0.40%增加至0.75%,每周期内小鼠自发肌电频次减少约50%,肌电发放时长变短,呈抑制状态;TUS/TMAS诱发肌电的成功率分别降低约50%和70%、潜伏期均延长约0.1 s、时长分别缩短约0.3和0.5 s,表明TUS/TMAS对运动皮层的调控效果随麻醉程度的加深而减弱。肢体自发和诱发肌电在发放率和时长上存在关联性特征,提示麻醉状态下小鼠自发肌电抑制状态可能是刺激效果减弱的影响因素之一。

肠道菌群代谢物TMAO与非酒精性脂肪性肝病的关系

目的检测NAFLD患者血清氧化三甲胺(TMAO)及其前体代谢物水平,及肠道中直肠真杆菌、多形拟杆菌、乳酸杆菌和双歧杆菌的表达量,探讨肠道菌群代谢物TMAO在NAFLD病程进展中的作用。方法随机选取118例受试者,分为NAFLD组86例和健康对照组32例,采用高效液相色谱串联质谱法检测受试者血清中TMAO及其前体代谢物的水平,qRT-PCR法检测粪便中目标细菌DNA的表达量。结果NAFLD患者血清TMAO、三甲胺(TMA)及胆碱水平明显升高(P<0.05),肝脏脂肪含量与TMAO的水平具有正相关性(P<0.05);NAFLD患者粪便中乳酸杆菌、直肠真杆菌表达量增加(P<0.05),双歧杆菌、多形拟杆菌表达量减少(P<0.05);血清TMAO水平与粪便中直肠真杆菌的数量呈正相关(r=0.280,P<0.05),与双歧杆菌的数量呈负相关(r=-0.332,P<0.05)。结论血清TMAO水平与NAFLD的严重程度呈正相关,NAFLD患者肠道菌群结构失衡,且与TMAO存在关联,推断肠道菌群可能通过代谢生成TMAO在NAFLD病程进展中起重要作用。

Simultaneous detection of CH_(4)and CO_(2)through dual modulation off-axis integrated cavity output spectroscopy

This study established a novel method for the simultaneous detection of two-component gases.Radio frequency(RF)white noise disturbance laser current and wavelength modulation were simultaneously used to improve the off-axis integrated cavity output spectroscopy technique,and a high-precision dual modulation OA-ICOS(RF-WM-OA-ICOS)system was established.The two laser beams were coupled into one laser beam that was applied incident to the cavity of RF-WM-OA-ICOS system.The second harmonic signals of CH_(4)and CO_(2)gas simultaneously appeared in the rising or falling edge of a triangular wave.This method was used to measure CH_(4)and CO_(2)with different concentrations.The results indicated that the proposed system has high stability and can accurately and simultaneously measure the concentrations of CH_(4)and CO_(2),with an optimal integration time of 220 s.The minimum detection limit was 10 ppb for CH_(4)and 1.5 ppm for CO_(2).The corresponding noise equivalent absorption sensitivity values were calculated as 2.67×10^(-13)cm^(-1)·Hz^(-1/2)and 5.18×10^(-11)cm^(-1)·Hz^(-1/2),respectively.The proposed dual-component gas simultaneous detection method can also be used for high-precision simultaneous detection of other gases.Therefore,this study may serve as a reference for developing portable multicomponent gas analyzers.

Characteristic Analysis of Off-Axis Meta-Lens

Meta-lens are a new type of planar optical element that can flexibly manipulate the phase, polarization and amplitude of the beam, and are currently receiving a great deal of attention as they are easier to process and manufacture. Off-axis meta-lens are a special type of meta-lens with a certain degree of dispersion that can be used as a beam-splitting element, providing a unique and feasible way to realize micro-miniature instruments. We analyze the effects of different numerical apertures and off-axis angles on the spectral resolution, focusing efficiency and simulation results of off-axis meta-lens to provide ideas for subsequent research and application of off-axis meta-lens. A number of off-axis meta-lens with parameters NA = 0.408 α = 13°, NA = 0.18 α = 13° and NA = 0.408 α = 20° were simulated through Lumerical software. The results show that the off-axis angle is related to the resolution;the larger the angle, the better the spectral resolution but the lower the focusing efficiency;when the numerical aperture is smaller, the smaller the coverage of the phase distribution, which will lead to a larger deviation between simulation and theory. The designer needs to balance the numerical aperture, off-axis angle and other parameters reasonably according to the requirements in order to achieve the desired effect. The findings of this study have important reference values for the theoretical analysis of off-axis meta-lens and the design of parameters in practical applications. .

Propagation of the off-axis superposition of partially coherent beams through atmospheric turbulence

The propagation properties of the off-axis superposition of partially coherent beams through atmospheric turbulence and their beam quality in terms of the mean-squared beam width w（z） and the power in the bucket （PIB） are studied in detail, where the effects of partial coherence, off-axis beam superposition and atmospheric turbulence are considered. The analytical expressions for the intensity, the beam width and the PIB are derived, and illustrative examples are given numerically. It is shown that the maximum intensity/max and the PIB decrease and w（z） increases as the refraction index structure constant Cn^2 increases. Therefore, the turbulence results in a degradation of the beam quality. However, the resulting partially coherent beam with a smaller value of spatial correlation parameter γ and larger values of separate distance Xd and beam number M is less affected by the turbulence than that with a larger value of y and smaller values of Xd and M. The main results obtained in this paper are explained physically.

Off-axis multi-wavelength dispersion controllingmetalens for multi-color imaging

Dispersion control is crucial in optical systems,and chromatic aberration is an important factor affecting imaging quality in imaging systems.Due to the inherent property of materials,dispersion engineering is complex and needs to trade off other aberration in traditional ways.Although metasurface offers an effective method to overcome these limits and results in well-engineered dispersion,off-axis dispersion control is still a challenging topic.In this paper,we design a single-layer metalens which is capable of focusing at three wavelengths(473 nm,532 nm,and 632 nm)with different incident angles(0°,-17°and 17°)into the same point.We also demonstrate that this metalens can provide an alternative for the bulky color synthetic prism in a 3-chips digital micromirror device(DMD)laser projection system.Through this approach,various off-axis dispersion controlling optical devices could be realized.

Far-field vector-diffraction of off-axis parabolic mirror under oblique incidence

Based on a full vector-diffraction theory, a detailed theoretical study is carried out, aiming at providing a clear insight into the effects of different focusing and off-axis parabola parameters on far-field vector-diffraction properties of an offaxis parabolic mirror in the presence of misalignments of the incoming beam. The physical origin of these effects is also explored. The results show that the far-field intensity profile is altered by the distortion-, coma-, and astigmatism-like aberrations, which are caused by oblique incidence rather than inherent aberrations for the off-axis configuration. The radius of 90% encircled energy also increases but does not change monotonically with incident beam size increasing, or rather,it first decreases and then increases. The focal shift strongly depends on the effective focal length and oblique incidence angle, but it is almost independent of the beam size, which affects the focusing spot patterns. The intensity distribution produces a higher astigmatic image with off-axis angle increasing. Coma-like aberration starts to become dominant with beam size increasing and results in larger curved propagation trajectory. The incident polarization also affects the intensity distribution. The variation in the Strehl ratio with oblique incidence angle strongly depends on the misalignment direction and beam size as well. In addition, we find that the difference in locus between the catacaustic and the diffraction focus in the meridian is small. But the locus of the sagittal foci is obviously different from the locus of the meridian foci and the catacaustic focus. Moreover, the peak intensity of the sagittal focus is maximum, and the ratio of the peak intensity to that in the meridian plane is approximately 1.5. Understanding these effects is valuable for assessing a practical focused intensity and describing the motion of charged particles under a strong electric field in ultraintense laser–matter interaction.

Study of structure-property relationship of semiconductor nanomaterials by off-axis electron holography

As the scaling down of semiconductor devices, it would be necessary to discover the structure-property relationship of semiconductor nanomaterials at nanometer scale. In this review, the quantitative characterization technique off-axis electron holography is introduced in details, followed by its applications in various semiconductor nanomaterials including group IV, compound and two-dimensional semiconductor nanostructures in static states as well as under various stimuli. The advantages and disadvantages of off-axis electron holography in material analysis are discussed, the challenges facing in-situ electron holographic study of semiconductor devices at working conditions are presented, and all the possible influencing factors need to be considered to achieve the final goal of fulfilling quantitative characterization of the structure-property relationship of semiconductor devices at their working conditions.

Multiple off-axis acoustic vortices generated by dual coaxial vortex beams

As a kind of special acoustic field, the helical wavefront of an acoustic vortex（AV） beam is demonstrated to have a pressure zero with phase singularity at the center in the transverse plane. The orbital angular momentum of AVs can be applied to the field of particle manipulation, which attracts more and more attention in acoustic researches. In this paper,by using the simplified circular array of point sources, dual coaxial AV beams are excited by the even-and odd-numbered sources with the topological charges of l_E and l_O based on the phase-coded approach, and the composite acoustic field with an on-axis center-AV and multiple off-axis sub-AVs can be generated by the superimposition of the AV beams for｜l_E｜ ≠ ｜l_O｜. The generation of edge phase dislocation is theoretically derived and numerically analyzed for l_E=-l_O. The numbers and the topological charges as well as the locations of the center-AV and sub-AVs are demonstrated, which are proved to be determined by the topological charges of the coaxial AV beams. The proposed approach breaks through the limit of only one on-axis AV with a single topological charge along the beam axis, and also provides the feasibility of off-axis particle trapping with multiple AVs in object manipulation.

系统性红斑狼疮合并TMA一例

一例早期确诊为系统性红斑狼疮的青年女性,病程长且反复发作,随着病程进展出现严重的血液系统损害,完善相关检查及肾活检后最终确诊为“狼疮肾炎Ⅳ+Ⅴ型伴TMA肾损伤”。予以激素冲击联合血浆置换、环磷酰胺联合贝利尤单抗免疫抑制治疗,取得较好效果。本病例警示临床医生对于狼疮肾炎的鉴别诊断,需考虑肾血管病变的存在,并积极治疗。

基于TMA/FMO3/TMAO通路探讨参竹心康方治疗慢性心力衰竭模型大鼠的作用机制

目的探讨参竹心康方对慢性心力衰竭模型大鼠的治疗作用及机制。方法将50只SPF级雄性SD大鼠按随机数字表法分为对照组,模型组,参竹心康方低、中、高剂量组,每组各10只。慢性心力衰竭大鼠模型的制备选择腹主动脉缩窄法,治疗组予参竹心康方灌胃,余下两组予生理盐水灌胃,此过程持续4周。末次给药后用小动物超声心动图检查大鼠心功能,WB检测肝脏黄素单氧化酶3(Flavin-containing monooxygenase 3,FMO3)表达水平,ELISA法测定血浆B型脑钠肽(Brain Natriuretic Peptide,BNP)、氧化三甲胺(Oxidetrimethylamine,TMAO)及粪便中三甲胺(Trimetlylamine,TMA)的表达,采用16SrDNA高通量测序法检测大鼠结肠内容物的菌群特征。结果与对照组比较,模型组LVESD、LVEDD指标水平明显升高,LVEF水平明显降低,差异有统计学意义(P<0.05);与模型组比较,参竹心康方低、中、高剂量组LVESD、LVEDD指标水平明显降低,LVEF水平明显升高,差异有统计学意义(P<0.05)。与对照组比较,模型组中FMO3的含量明显升高,差异有统计学意义(P<0.05);与模型组比较,参竹心康方低、中、高剂量组中FMO3的含量明显降低差异有统计学意义(P<0.05)。与对照组比较,模型组中TMA的表达量明显升高,差异有统计学意义(P<0.05);与模型组比较,参竹心康方低、中剂量组中TMA含量明显降低,差异有统计学意义(P<0.05)。与对照组比较,模型组大鼠血浆BNP、TMAO含量均明显升高,差异有统计学意义(P<0.05);药物治疗之后,参竹心康方低、中、高剂量组BNP、TMAO含量较模型组均明显降低,差异有统计学意义(P<0.05)。与对照组比较,模型组Shannon、Chao1指数值升高,Simpson指数值下降,差异有统计学意义(P<0.05)。参竹心康中剂量组Shannon、Chao1、Simpson指数值回调与模型组比较,差异有统计学意义(P<0.05)。肠道菌群的Alpha、Beta多样性分析表明,与对照组比较,模型组大鼠菌群丰度及多样性呈下降趋势,而参竹心康方组大鼠肠菌的丰富度及多样性均明显增加。结论参竹心康方对慢性心力衰竭大鼠的保护作用可能与改善肠道菌群紊乱、调控TMA/FMO3/TMAO通路及其相关蛋白的表达相关。

Optical Design for the Off-axis Reflective Optics with Wide Field

Reflective optics with wide field of view has been applied more and more widely in EUVL or space optics, and also plays an important role in promoting scientific and technological research. Among the reflective optics, the off-axis reflective optics is the most hopeful solution to the ever-highest demands of these applications. This paper gives the requirements of both the above mentioned applications and the similarities and differences between these two kinds of optical systems. Finally, a design example of off-axis reflective optics with wide field of view is presented and described.

Properties of off-axis hollow Gaussian–Schell model vortex beam propagating in turbulent atmosphere

The analytical expression of off-axis hollow Gaussian–Schell model vortex beam(HGSMVB)generated by anisotropic Gaussian–Schell model source is first introduced.The evolution properties of off-axis HGSMVB propagating in turbulent atmosphere are analyzed.The results show that the off-axis HGSMVB with smaller coherence length or propagating in stronger turbulent atmosphere will evolve from dark hollow beam into Gaussian-like beam with a larger beam spot faster.The beams with different values of integer order N or the position for hollow and vortex factor R will have almost the same Gaussian-like spot distribution at the longer propagation distance.

Effects of trapped electrons on off-axis lower hybrid current drive in tokamaks

The effects of trapped electrons on off-axis lower hybrid current drive （LHCD） in tokamaks are studied, A computer code for solving the Fokker-Planck equation in a toroidal geometry is developed and employed. The code is suitable for various auxiliary heating and current drive schemes in tokamak plasmas. The influence of the resonance regime on the current drive efficiency as well as the influence of trapped particle fraction on the current drive efficiency are emphasized. It is shown that, as an electrostatic force, the lower hybrid wave causes some of the trapped electrons to be untrapped and lose their energy, which can cut the LHCD efficiency by about 30%. The ITER scaling law is also used to estimate the trapped electron effects.

Nonparaxial propagation of a vectorial apertured off-axis Lorentz beam

Based on the vectorial Ftayleigh-Sommerfeld integral formula and the complex Gaussian expansion of the hardedge aperture function, an analytical propagation expression for a nonparaxial vectorial off-axis Lorentz beam passing through a rectangular aperture is derived. The unapertured case, the far field expression and the scalar paraxial result are also presented as special cases of the general formulae, respectively. Some numerical examples are also given to show the propagation characteristics of a nonparaxial vectorial off-axis Lorentz beam through a rectangular aperture. It is indicated that the f parameter, the off-axis displacement and the truncation parameter all play an important role in determining nonparaxial propagation behaviour.

Controllable Crack Propagation in Off-Axis Crushing of Stitched Composite Absorbers

Crack growth resistance plays a different role in crashworthiness analysis since the progressive energy absorption is based on controllable fracture mechanisms. In this regard, the present paper studies the efficient crack growth resistance in off-axis crushing of composite tubular structures by implementing natural fiber yarns. One of the through-to-thickness reinforcement methods known as stitching has been chosen to influence the axial and off-axis crushing process. Improving the crack growth resistance and appropriate fiber breakage at different stages of crushing process can significantly improve the resistance force and consequently the energy absorption capability of composite absorbers in axial and off-axis crushing. This analysis will be applied to non-stitched and stitched CFRP composite boxes which showed brittle fracture and transverse shearing crushing modes under off-axis loading of 10 degrees. The analytical methods are also implemented to analysze the effect of various failure mechanisms such as bending, friction, bundle fracture, and interlaminar crack growth for the observed crushing modes. The proposed model is able to predict the crushing load and crush force efficiency in close agreement from experimental studies.

Laminate Tailoring of Composite Tubular Structures to Improve Crashworthiness Design at Off-Axis Loading

This paper presents experimental and numerical investigation on the parameters effecting energy absorption capability of composite tubular structures at oblique loading to improve crashworthiness performance. Various inclined angles of 5°, 10°, 20° and 30° were selected for the study of off-axis loading. The results indicate that by increasing the lateral inclination angle the mean crushing force and also energy absorption capability of all tested sections decreased. From design perspective, it is necessary to investigate the parameters effecting this phenomenon. The off-axis loading effect that causes significant reduction in energy absorption was investigated and the effected parameters were improved to increase energy absorption capability. To establish this study, 10° off-axis loading was chosen to illustrate the obtained improvement in energy absorption capability. Five cases were studied with combinations of ply-orientation and flat trimming with 45° chamfer. This method was applied to the integrated 10° off-axis loading and the final results showed significant improvement in energy absorption capability of composite absorbers. Finite element model (FEM) was developed to simulate the crushing process of axial and off-axis composite section in LS-DYNA and the results were in good agreement with the experimental data.