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Psychosocial Factors Associated with Transfer Anxiety among Open Heart Surgery Patients Transferred from the Intensive Care Unit to the General Ward
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作者 Jaya Rijal Wipa Sae-Sia Luppana Kitrungrote 《Health》 2020年第12期1583-1597,共15页
<strong>Introduction:</strong> Patient’s transfer from the intensive care unit (ICU) to the general ward indicates their improving health status. However, the transfer produces anxiety when patients enter... <strong>Introduction:</strong> Patient’s transfer from the intensive care unit (ICU) to the general ward indicates their improving health status. However, the transfer produces anxiety when patients enter an unfamiliar environment with different care protocols and circumstances. <strong>Objectives:</strong> This study aimed to examine the level of ICU transfer anxiety among open heart surgery patients and determine the psychosocial factors associated with ICU transfer anxiety among open heart surgery patients. <strong>Methods:</strong> Data were collected in a cardiac center in Kathmandu City, Nepal among 95 open heart surgery patients within 24 hours of their transfer from an ICU to a general ward. The study used four self-reported questionnaires, namely the modified Mishel Uncertainty in Illness Scale for Adults, modified Brief COPE Inventory, Nurses’ Support Questionnaire, and State Anxiety Inventory. <strong>Results:</strong> Fifty-two patients (54.7%) had a high level of transfer anxiety. Spearman’s rank correlation showed that uncertainty in illness, coping, and nurses’ support were significantly related to transfer anxiety (<em>p</em> < 0.001). <strong>Conclusion:</strong> The results of this study suggest nurses to address uncertainty in illness of the patients, improve their coping abilities, and provide need-based nursing support to them during the transitional phase. Besides, clinicians and governmental agencies should contribute to implication of transitional guidelines, which can reduce transfer anxiety and promote health and recovery of the patients. 展开更多
关键词 Transfer Anxiety UNCERTAINTY COPING Intensive Care Unit open heart Surgery
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RELEASE OF SERUM TROPONIN I AND ITS RELATIONSHIP TO MULTIFACTORS FOLLOWING OPEN HEART SURGERY IN CHILDREN
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作者 蔡及明 史珍英 +3 位作者 周燕萍 陈玲 苏肇伉 杨艳敏 《Journal of Shanghai Second Medical University(Foreign Language Edition)》 2005年第2期91-95,共5页
Objective To be released specifically after myocardial damage. The goal of this study was to measure serum cardiac troponin I levels after open heart surgery in children, and to evaluate relevance between TnTi and per... Objective To be released specifically after myocardial damage. The goal of this study was to measure serum cardiac troponin I levels after open heart surgery in children, and to evaluate relevance between TnTi and perioperative multi-factors. Methods Fifty-seven consecutive pediatric patients undergoing elective correction of congenital heart diseases were divided into group A ( TOF, n =31 ) and group B ( VSD, n =26). Blood sampies were drawn preoperatively, 5min( T0 ) , 6h( T6 ) , 12h( T12 ) , 24h( T24 ) , 48h( T48 ) , 72h( T72 ) after removal of aortic cross clamping. Myocardial protection consisted of moderate systemic hypothermia ( 30℃- 32℃ ), cold crystalloid cardioplegia and topical cooling. Demographic information, cardiac defect, repair procedure, duration of bypass ( CPBT) , cross-clamping time ( CCT) , clinical score for cardiac function, electrocardiographic changes and outcomes were recorded. Results Compared with the baseline value, serum concentration of troponin I peaked at T0 ( P 〈 0. 01 ), and fell to normal level at T72 ( P 〉 0. 05 ). Peak CTnI was 118 and 55 times higher than the baseline value, respectively in group A and group B. There was a positive correlation between peak CTnI and CPBT, CCT ( r = 0. 51 ; P 〈 0. 01 ), myocardial operative injury after ventriculotomy and muscle resection ( r = 0. 35, P 〈0. 01 ). Also the peak CTnl value was correlated to the clinical score for cardiac function (r = -0. 52; P 〈0. 01). 2.3μg/L was a cutoff value which was highly predictive for postoperative recovery and inotropic support. Conclusion Postoperative serum troponin I is a highly specific and sensitive marker for myocardial ischemia and injury; therefore, its measurement may contribute to the assessment of recovery and outcome after open heart surgery. 展开更多
关键词 cardiac troponin I myocardial injury open heart surgery cardiac function
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CHANGES ON RECEPTOR EXPRESSIONAND PRODUCTION OF INTERLEUKIN-2 IN CIRCULATING LYMPHOCYTE POPULATION AFTER OPEN HEART SURGERY 被引量:1
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作者 罗爱林 田玉科 金士翱 《Chinese Medical Sciences Journal》 CAS CSCD 1997年第4期220-223,共4页
To evaluate the change of perioperative cell mediated immunity after cardiac operation with cardiopul-monary bypass (CPB), so as to provide some information for timely prevention and treatment against post-operative i... To evaluate the change of perioperative cell mediated immunity after cardiac operation with cardiopul-monary bypass (CPB), so as to provide some information for timely prevention and treatment against post-operative immunological disorder, 40 patients were studied. By searching for the effects of CPB and anes-thesia, interleukln-2 receptor (IL-2R) expression upon the surface of peripheral blood mononuclear cells(PBMC), as well as interleukin-2 (IL-2) production in vitro was traced 55 min after anesthesia, at end ofCPB, on postoperative 1, 7, and 14 day versus preanesthesia control. Our data demonstrated that expres-sion of IL-2R on PBMC was significantly suppressed in all comparing with the baseline value, meanwhile,IL-2 production in vitro also statistically dropped. However,no statistical difference was found on perioper-ative IL 2R expression and IL-2 synthesis in the cholecystectomy group. We conclude that postoperativeimmunological disorder seems to be the main factor, which could be denoted as reduced IL 2R expressionon PBMC and lL-2 synthesis in vitro for sepsis, even multiple system organ failure developed after cardiacsurgery. 展开更多
关键词 interleukin-2 receptor INTERLEUKIN-2 open heart surgery
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Release of Serum Troponin I and its Relationship to Multifactors Following Open Heart Surgery in Children
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作者 CAI Ji-ming SHI Zhen-ying ZHOU Yan-ping CHEN Lin SU Zhao-kang YANG Yan-min 《上海第二医科大学学报》 CSCD 北大核心 2005年第10期1053-1053,共1页
关键词 血清肌钙蛋白I 开放性心脏手术 儿童 致病因子
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Effect of Oxygen Therapy by Venturi Mask versus Non Invasive Ventillation on the Outcome of Patients Who Devolope Hypoxia after Open Heart Surgery
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作者 Yousry El-Saied Rizk Tarek Samy Essawy +2 位作者 Ahmed Hamdy Abd Elrahman Ali Mohamed Ahmed El-Gazzar Abdelkhalek Fouad Mahmoud 《Open Journal of Anesthesiology》 2018年第9期241-254,共14页
Background: Cardiothoracic surgery is a common cause of acute respiratory failure and is associated with increased morbidity and mortality. We aimed to compare the outcomes of open heart surgery patients treated using... Background: Cardiothoracic surgery is a common cause of acute respiratory failure and is associated with increased morbidity and mortality. We aimed to compare the outcomes of open heart surgery patients treated using oxygen delivery devices with patients who receive NIV as a first-line therapy for hypoxemic respiratory failure. Materials and Methods: 40 patients who developed acute hypoxemic respiratory failure after open heart surgery and admitted to cardiothoracic ICU 20 patients received NIV and 20 patient received oxygen by venture mask. For all patients the following measurements were performed before and after CPAP AND Venture use: CBC, blood urea, serum creatinine body temperature, chest X-ray, Arterial blood gases (arterial pH, sodium bicarbonate, pcO2, SpO2 and PaO2-to-FiO2 ratio). Results: Mean PO2 and SO2 have increased after using of both venture and Cpap, increase in both PCO2 and HCO3 levels after using Venturi mask, CPAP mask was superior to venturi mask in avoiding the need of intubation, decreasing The ICU stay median length and also median length of hospitalization, all were lower in CPAP group than venture group. Also the mortality rate was lower in CPAP group than the venturi group. Conclusion: Using CPAP mask in severe AHRF following open heart surgery can avoid intubation, decreases the levels of tachypnea and arterial hypoxemia, decreases ICU stay, the length of hospitalization and also decreases the mortality rate compared with patients receiving high-concentration oxygen therapy with venture mask. 展开更多
关键词 open heart Surgery VENTURE MASK CPAP MASK Non INVASIVE Ventilation O2 Therapy
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Combination of balanced ultrafiltration with modified ultrafiltration attenuates pulmonary injury in patients undergoing open heart surgery 被引量:19
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作者 黄惠民 姚廷俊 +4 位作者 王伟 朱德明 张蔚 陈虹 付维定 《Chinese Medical Journal》 SCIE CAS CSCD 2003年第10期1504-1507,共4页
Objective To explore the effects of ultrafiltration technique in preventing and relieving pulmonary injury in children undergoing open heart surgery and cardiopulmonary bypass (CPB). Methods Thirty cases with congenit... Objective To explore the effects of ultrafiltration technique in preventing and relieving pulmonary injury in children undergoing open heart surgery and cardiopulmonary bypass (CPB). Methods Thirty cases with congenital heart defects were divided into a control group and an experimental group. In the control group,conventional cardiopulmonary bypass was used without ultrafiltration; while in the experimental group,cardiopulmonary bypass with balanced ultrafiltration and modified ultrafiltration were used. Pulmonary static compliance (C stat ),airway resistance (R aw ),alveolar-arterial oxygen difference (A-a DO 2),hematocrit (HCT),serum albumin (Alb),interleukin-6 (IL-6),endothelia-1 (ET-1) and thromboxane (TXB 2) were measured. Results The pulmonary function was improved,HCT and serum albumin concentrations were increased,and some harmful medium-size solutes were decreased in the experimental groups compared with the control group.Conclusions Combination of balanced ultrafiltration with modified ultrafiltration can effectively concentrate blood,exclude harmful inflammatory mediators,and attenuate lung edema and inflammatory responsive pulmonary injury. 展开更多
关键词 ultrafiltration · open heart surgery · cardiopulmonary bypass · pulmonary preservation
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Comparative study on cerebral injury after open heart surgery in patients with congenital and rheumatic heart disease 被引量:3
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作者 王咏 肖颖彬 +2 位作者 陈林 钟前进 王学锋 《Chinese Journal of Traumatology》 CAS 2005年第4期249-252,共4页
Objective: To comparatively study the different effects of open heart surgery on brain tissues of patients with congenital and rheumatic heart disease. Methods: Forty patients with congenital heart disease (CHD, CHD g... Objective: To comparatively study the different effects of open heart surgery on brain tissues of patients with congenital and rheumatic heart disease. Methods: Forty patients with congenital heart disease (CHD, CHD group, n=20) or rheumatic heart disease (RHD, RHD group, n=20) underwent on-pump (cardiopulmonary bypass, CPB) heart-beating open heart surgery. Blood samples before CPB, and 20 minutes, 1 hour, 24 hours and 7 days after CPB were collected, and the levels of neuron-specific enolase (NSE) and protein S-100b in the plasma were determined with enzyme-linked immunoadsorbent assay (ELISA), respectively. All the patients were examined with electroencephalogram (EEG) before and 1 week after operation. The changes of NSE, S-100b and EEG compared to verify the difference of postoperative cerebral injury between CHD cases and RHD cases. Results: The plasma level of S-100b increased significantly 20 minutes after CPB and was still higher than the preoperative level at 24 hours after operation in both groups (P< 0.01). The plasma level of NSE increased more significantly in the CHD group than in the RHD group 20 minutes after CPB and it returned to the normal level 24 hours after CPB in the CHD group but remained at a high level in the RHD group (P< 0.01). The levels of NSE and S-100b returned to the normal levels on the 7th day after CPB. Abnormal EEG was found in 75% of the patients in the CHD group and 60% in the RHD group. Conclusions: On-pump heart-beating open heart surgery can cause certain cerebral injury in the patients with CHD or RHD. The injury was more severe and recovered more quickly in the CHD group than in the RHD group. 展开更多
关键词 Brain injuries Rheumatic heart disease Cardiopulmonary bypass open heart surgery
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Efficacy of amiodarone and lidocaine for preventing ventricular fibrillation after aortic cross-clamp release in open heart surgery:a meta-analysis of randomized controlled trials 被引量:2
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作者 Yong ZHENG Qiang GU +4 位作者 Hong-wu CHEN Huai-ming PENG Dong-yu JIA Yu ZHOU Mei-xiang XIANG 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2017年第12期1113-1122,共10页
Objective: The relative preventative efficacy of amiodarone and lidocaine for ventricular fibrillation(VF) after release of an aortic cross-clamp(ACC) during open heart surgery has not been determined. This meta-... Objective: The relative preventative efficacy of amiodarone and lidocaine for ventricular fibrillation(VF) after release of an aortic cross-clamp(ACC) during open heart surgery has not been determined. This meta-analysis was designed to systematically evaluate the influence of amiodarone, lidocaine, or placebo on the incidence of VF after ACC. Methods: Prospective randomized controlled trials(RCTs) that compared the VF-preventative effects of amiodarone with lidocaine, or amiodarone or lidocaine with placebo were included. Pub Med, EMBASE, and the Cochrane Library were searched for relevant RCTs. Fixed or randomized effect models were applied according to the heterogeneity of the data from the selected studies. Results: We included eight RCTs in the analysis. Pooled results suggested that the preventative effects of amiodarone and lidocaine were comparable(relative risk(RR)=1.12, 95% confidence interval(CI): 0.70 to 1.80, P=0.63), but both were superior to the placebo(amiodarone, RR=0.71, 95% CI: 0.51 to 1.00, P=0.05; lidocaine, RR=0.63, 95% CI: 0.46 to 0.88, P=0.006). The percentage of patients requiring electric defibrillation counter shocks(DCSs) did not differ significantly among patients administered amiodarone(RR=0.21, 95% CI: 0.04 to 1.19, P=0.08), lidocaine(RR=2.44, 95% CI: 0.13 to 44.02, P=0.55), or the placebo(RR=0.56, 95% CI: 0.25 to 1.25, P=0.16). Conclusions: Amiodarone and lidocaine are comparably effective in preventing VF after ACC, but the percentage of patients who subsequently require DCSs does not differ among those administered amiodarone, lidocaine, or placebo. 展开更多
关键词 AMIODARONE LIDOCAINE Ventricular fibrillation open heart surgery
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OpenSSL HeartBleed漏洞分析及检测技术研究 被引量:5
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作者 强小辉 陈波 陈国凯 《计算机工程与应用》 CSCD 北大核心 2016年第9期88-95,101,共9页
HeartBleed漏洞是一个严重的安全漏洞。分析了OpenSSL中心跳机制的源代码,在代码层次总结了HeartBleed漏洞产生的原因。采用Python语言实现了漏洞检测脚本工具,通过发送心跳信息长度与长度字段不一致的心跳数据包,并根据响应数据包的类... HeartBleed漏洞是一个严重的安全漏洞。分析了OpenSSL中心跳机制的源代码,在代码层次总结了HeartBleed漏洞产生的原因。采用Python语言实现了漏洞检测脚本工具,通过发送心跳信息长度与长度字段不一致的心跳数据包,并根据响应数据包的类型和响应数据的长度,判断目标是否存在HeartBleed漏洞。针对应用OpenSSL的Web网站以及网络服务的服务器进行了检测实验。与已有检测工具的比较实验表明,实现的检测脚本工具检测范围广,检测时间快,正确率高,可以有效完成HeartBleed漏洞的检测工作。 展开更多
关键词 安全套接层协议(SSL) openSSL heartBleed漏洞 漏洞检测 软件安全开发
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基于HEART沟通模式的“态度-定义-开放思维-计划-实施”护理方案在数字化导板种植中的应用
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作者 吴少梅 刘会茹 陈俊兰 《中国当代医药》 CAS 2024年第21期176-180,共5页
目的探讨分析数字化导板种植患者实施基于HEART沟通模式的“态度-定义-开放思维-计划-实施”护理方案的应用效果。方法选取2021年1月至2023年1月广东省中山市口腔医院种植修复中心收治的108例数字化导板种植患者作为研究对象,按照随机... 目的探讨分析数字化导板种植患者实施基于HEART沟通模式的“态度-定义-开放思维-计划-实施”护理方案的应用效果。方法选取2021年1月至2023年1月广东省中山市口腔医院种植修复中心收治的108例数字化导板种植患者作为研究对象,按照随机数字表法分为护理A组(54例)与护理B组(54例)。护理A组采用常规临床护理方法,护理B组则在A组护理方案上采用基于HEART沟通模式的“态度-定义-开放思维-计划实施”护理方法。比较两组患者的护理满意度、焦虑评分、疼痛程度、种植体边缘骨吸收状态、临床指标改善情况、自我效能、疾病知晓率与治疗依从性。结果护理B组患者干预后的总满意度高于护理A组,差异有统计学意义(P<0.05);护理B组患者干预后的焦虑评分低于护理A组,差异有统计学意义(P<0.05);护理B组患者干预后的疼痛程度指标低于护理A组,差异有统计学意义(P<0.05);护理B组患者在术后1、3、5个月的种植体边缘骨吸收状态低于护理A组,差异有统计学意义(P<0.05);护理B组患者干预后的并发症总发生率低于护理A组,差异有统计学意义(P<0.05)。结论数字化导板种植患者实施基于HEART沟通模式的护理干预的效果显著,不仅可提高患者的满意度,还可减轻其焦虑与疼痛程度,有利于改善骨吸收状态,并发症少,值得推广。 展开更多
关键词 heart沟通模式 “态度-定义-开放思维-计划-实施”护理 数字化导板 种植
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Metabolic Acidosis in the Surgical Intensive Care Unit: Risk Factors, Clinical Correlates and Outcome. Findings from a High Dependency Heart and Vascular Surgical Center in Nigeria 被引量:1
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作者 P. K. Uduagbamen M. Sanusi +3 位作者 O. B. Udom O. F. Salami A. D. Adebajo O. J. Alao 《World Journal of Cardiovascular Surgery》 2020年第11期226-241,共16页
<strong>Background:</strong> <span style="font-size:12px;font-family:Verdana;">Metabolic acidosis (MA) is a common finding on the surgical ward, more so in the intensive care unit. Diseases... <strong>Background:</strong> <span style="font-size:12px;font-family:Verdana;">Metabolic acidosis (MA) is a common finding on the surgical ward, more so in the intensive care unit. Diseases affecting the major organ systems of the body and higher grades of surgery are common risk factors for MA. It is associated with poor treatment outcome. </span><b><span style="font-size:12px;font-family:Verdana;">Aim</span></b><b><span style="font-size:12px;font-family:Verdana;">:</span></b><b><span style="font-size:10.0pt;font-family:;" "=""> </span></b><span style="font-size:12px;font-family:Verdana;">To determine the risk factors and clinical correlates of metabolic acidosis and assess its relationship with treatment outcome. </span><b><span style="font-size:12px;font-family:Verdana;">Methodology:</span></b><span style="font-size:12px;font-family:Verdana;"> A retrospective study at the “Tristate Heart and vascular Center” in Ilishan-Remo South west Nigeria, on patients that had cardiac and vascular surgeries </span><span style="font-size:12px;font-family:Verdana;">from</span><span style="font-size:10.0pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;"> January 2015 to De</span><span style="font-family:Verdana;font-size:12px;">cember 2019. Three hundred and forty two participants took part in the </span><span style="font-family:Verdana;font-size:12px;">study. The demographic, clinical and laboratory findings were entered. Statistical analysis was with Student’s t-test and Chi square. </span></span><b><span style="font-size:12px;font-family:Verdana;">Results:</span></b><span style="font-size:12px;font-family:Verdana;"> Two hundred and six males and 136 females were studied. The incidence</span><span style="font-size:12px;font-family:Verdana;">s</span><span style="font-size:10.0pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;"> of metabolic acidosis prior to induction, on post-operative day one (POD</span><sup><span style="font-family:Verdana;font-size:12px;">1</span></sup><span style="font-family:Verdana;font-size:12px;">) and on POD</span><sup><span style="font-family:Verdana;font-size:12px;">28</span></sup> <span style="font-family:Verdana;font-size:12px;">were 20.7%, 39.8% and 14.1%</span></span><span style="font-size:12px;font-family:Verdana;"> respectively</span><span style="font-size:12px;font-family:Verdana;">. Nine (2.6%) participants died</span><span style="font-size:10.0pt;font-family:;" "=""><span style="font-family:Verdana;font-size:12px;"> during admission, of this, 6 (66.7%) had MA at presentation but all (100%) had MA on POD</span><sup><span style="font-family:Verdana;font-size:12px;">1</span></sup><span style="font-family:Verdana;font-size:12px;">. The Risk factors for MA were advanced age, comorbidities, open heart surgery, elevated systolic blood pressure and low eGFR. Metabolic acidosis was a risk factor for prolonged hospital stay, perioperative death and declining kidney function which was commoner among participants with preexisting kidney dysfunction.</span></span><b><span style="font-size:12px;font-family:Verdana;"> Conclusion: </span></b><span><span>The incidence of metabolic acidosis was 20.7% at induction of anesthesia, rose to 39.8% on POD</span><sup><span>1</span></sup><span> and by POD</span><sup><span>28</span></sup><span>, it has significantly reduced to 14.1%. While advancing age and comorbidities were risk factors for MA, the occurrence of MA increased the risk of declining kidney function, prolonged hospital stay and death.</span></span> 展开更多
关键词 Metabolic Acidosis PERIOPERATIVE Anesthetic Induction Post-Operative Day open heart VASCULAR COMORBIDITIES Kidney Function
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Renal Outcomes and Myocardial Performance after On-Pump Beating Heart versus Conventional On-Pump Surgery in Patients with Preoperative Low Glomerular Filtration Rate
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作者 Salih Colak Davut Azboy +5 位作者 Zeki Temizturk Hakan Atalay Omer Faruk Dogan Dilek Dogan Emjed Khalil Kenan Abdurrahman Kara 《World Journal of Cardiovascular Diseases》 2016年第11期433-445,共14页
Objective: Acute kidney disease develops 16% - 30% of patients with preoperative impaired renal functions. Our aim of this study was to compare postoperative renal outcomes using two open heart surgery techniques, on-... Objective: Acute kidney disease develops 16% - 30% of patients with preoperative impaired renal functions. Our aim of this study was to compare postoperative renal outcomes using two open heart surgery techniques, on-pump beating heart (OPBH) and conventional on-pump (COP), in patients who have preoperative low glomerular filtration rate (eGFR) as an indicator of creatinine clearance. Methods: From 2004 to 2015, 341 patients with preoperative creatinine clearance were lower than 90 ml/min/1.73m2 were selected for this study. On-Pump beating heart was performed in 111 patients (Group I). Conventional on-pump technique was used in 200 patients. In the remaining patients, we measured postoperative Tumor Necrosis Factor Alpha (TNF-alpha), cardiac troponin I (cTn-I), Brain natriuretic peptid (NT-Pro- BNP), creati-nine (Cr), blood urea nitrogen (BUN) and postoperative eGFR daily until day four after surgery. Results: There were no differences in baseline levels of TNF-alpha, NT-Pro-BNP, BUN, cTn-I, Cr levels between the groups. Cardiopulmonary bypass (CPB) time were much longer and cumulative inotrope use was significantly higher in patients underwent COP (P Conclusion: Our study showed that on-pump beating heart CABG technique provides a morbidity benefit and is associated with a lower risk of peroperative LOS in patients with mild renal disfunction. Our study results suggest that OPBH is superior to the COP in terms of postoperative renal injury and cardiac mediators. 展开更多
关键词 open heart Surgery Beating heart Postoperative Renal Failure
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SURGICAL EXPERIENCE OF COMPLEX CONGENITAIL HEART DEFECTS IN CHILDREN AND INFANTS
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作者 丁文祥 苏肇伉 徐志伟 《Medical Bulletin of Shanghai Jiaotong University》 CAS 1992年第1期58-62,共5页
From January 1982 to June 1990, 2730 patients with congenital heart defects (CHDS) were treated at Xinhua Hospital there were 537 cases of complex lesions. Fifty of 537 patients died, the hospital mortality rate was 9... From January 1982 to June 1990, 2730 patients with congenital heart defects (CHDS) were treated at Xinhua Hospital there were 537 cases of complex lesions. Fifty of 537 patients died, the hospital mortality rate was 9.31%. On the basis of our clinical experience, it is important that the accurate diagnosis was made promptly in neonate with complex CHDs. The surgical results can be improved by the use of PGEI and balloon atrial septostomy in the cyanotic neonate. For the congestive CHDs, the operation must be per formed in the early life to prevent pulmonary hypertension. Improved methods of preoperative and postoperative care have contributed to these results. 展开更多
关键词 CONGENITAL heart disease CARDIAC SURGERY open-heart SURGERY
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Heart Surgery Practice in Sub Saharan Africa: Single Nigerian Institutional Midterm Results and Challenges
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作者 Jonathan O. Nwiloh Mobolaji A. Oludara Philip A. Adebola 《World Journal of Cardiovascular Surgery》 2014年第3期35-41,共7页
Background: The majority of prospective cardiac surgical patients in sub Saharan Africa lack access to open heart surgery. We reviewed our midterm results to identify the obstacles to growth and challenges with sustai... Background: The majority of prospective cardiac surgical patients in sub Saharan Africa lack access to open heart surgery. We reviewed our midterm results to identify the obstacles to growth and challenges with sustainability. Methods: Records of patients undergoing heart surgery at LASUTH from December 2004 to March 2006 were retrospectively reviewed for clinical and outcome data. Results: Twenty four patients age 10-50, mean 28.0 +/? 10.49 years and 13 (54.2%) males underwent surgery. 12 (50.0%) patients had mechanical valve replacements, 11 (45.8%) closure of septal defects and 1 (4.2%) left atrial myxoma resection. Logistic euroscore for valve patients was 5.81 +/? 4.74 while observed mortality was 8.3% (1/12). Overall 30 days operative mortality was 8.3% (2/24) and major morbidity 4.2% (1/24). Patients with septal defects closure stopped clinic visits within a year. Valve patients follow up was complete in 90.1% with mean duration of 55.2 +/? 15.3 months. Late events occurred only in females with mitral valve replacements. The 5-year freedom from thromboembolism and bleeding was 74.0% and survival 82.0% in valve patients. Conclusion: Despite limited resources heart surgery can safely be performed with good outcomes by trained local personnel under supervision of visiting foreign teams until they are proficient to operate independently. Patients with less complex congenital defects have excellent postsurgical outcomes, while patients with rheumatic valve replacement are subject to ongoing valve related morbidity and mortality therefore require lifetime follow up. Choice of prosthetic valve for the mostly indigent and poorly educated population remains a challenge. We now prefer stented tissue valve despite its known limitations, in child bearing age females desirous of childbirth and others unlikely to comply with anticoagulation regimen. Barriers to sustainability include poor infrastructures, few skilled manpower, inadequate funding and restricted patient access due to inability to pay without third party insurance or government Medicaid. 展开更多
关键词 open heart Surgery PROSTHETIC VALVE CHOICE ANTICOAGULATION
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左侧星状神经节阻滞对心内直视术患者血流动力学及预后的影响
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作者 徐明清 陈文 +2 位作者 万震威 张伟平 廖成全 《中国实用医药》 2024年第21期48-51,共4页
目的 探究左侧星状神经节阻滞对心内直视术患者血流动力学及预后的影响。方法 选取111例心内直视术患者作为研究对象,依据随机数字分配法分为观察组(56例)和对照组(55例)。对照组患者给予局部麻醉(局麻)后采集右侧颈内的血液标本并实行... 目的 探究左侧星状神经节阻滞对心内直视术患者血流动力学及预后的影响。方法 选取111例心内直视术患者作为研究对象,依据随机数字分配法分为观察组(56例)和对照组(55例)。对照组患者给予局部麻醉(局麻)后采集右侧颈内的血液标本并实行心内直视术,观察组患者在对照组基础上实行左侧星状神经节阻滞术。比较两组患者在逆行置管后(T0)、主动脉开放10 min(T1)、术后2 h(T2)、术后6 h(T3)、术后24 h(T4)时的血流动力学指标、血浆炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-8(IL-8)、白细胞介素-10(IL-10)]水平及血浆神经组织蛋白(S100β)、神经元特异性烯醇化酶(NSE)水平。结果 两组患者T0~T4时平均动脉压(MAP)、心率(HR)无明显差异(P>0.05)。两组患者T0时血浆炎症因子水平无明显差异(P>0.05);两组患者T1~T4时TNF-α、IL-8、IL-10均高于T0时,且观察组患者T1~T4时TNF-α、IL-8、IL-10均优于对照组(P<0.05)。两组患者TNF-α、IL-8、IL-10在T1~T4时随着时间变化先升高后降低,以T2时水平达到最高。T0~T4时,观察组患者S100β分别为(0.33±0.10)、(1.26±0.25)、(1.02±0.04)、(0.67±0.15)、(0.43±0.11)μg/L, NSE分别为(7.68±0.59)、(10.09±0.78)、(9.41±0.62)、(9.10±0.66)、(8.01±0.51)μg/L;对照组患者S100β分别为(0.31±0.08)、(1.52±0.35)、(1.18±0.12)、(1.05±0.33)、(0.52±0.25)μg/L, NSE分别为(7.56±0.65)、(11.35±1.33)、(10.66±1.01)、(10.56±1.02)、(8.98±0.68)μg/L。相比于T0时,两组患者的S100β、NSE水平在T1~T4时均有所上升(P<0.05);相比于对照组,观察组患者的S100β及NSE水平在T1~T4时均降低(P<0.05)。结论 左侧星状神经节阻滞对心内直视术患者血流动力学影响较小,且可减轻患者体内的炎症反应,改善神经因子。 展开更多
关键词 左侧星状神经节阻滞 心内直视术 血流动力学 炎症因子
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右腋下小切口与胸骨正中切口两种入路方式治疗先天性心脏病患儿的效果观察
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作者 李晓恒 李燕平 +1 位作者 付晓可 李斌 《临床研究》 2024年第6期12-15,共4页
目的探讨先天性心脏病患者采取不同入路手术治疗的临床价值。方法抽取洛阳市中心医院2021年1月至2023年12月收入的先天性心脏病患儿70例,依据不同手术方式分为对照组与观察组,各35例,对照组接受胸骨正中切口,观察组接受右腋下小切口,对... 目的探讨先天性心脏病患者采取不同入路手术治疗的临床价值。方法抽取洛阳市中心医院2021年1月至2023年12月收入的先天性心脏病患儿70例,依据不同手术方式分为对照组与观察组,各35例,对照组接受胸骨正中切口,观察组接受右腋下小切口,对两组患儿临床指标(手术时间、体外循环时间、输血量、胸腔引流量、主动脉阻断时间、住院时间),疼痛程度,呼吸功能及并发症发生情况进行组间比较。结果两组患儿手术时间、体外循环时间、主动脉阻断时间相比,差异无统计学意义(P>0.05),观察组输血量、胸腔引流量均低于对照组,且住院时间短于对照组,差异有统计学意义(P<0.05);两组患儿各时间段呼吸功能指标相比,差异无统计学意义(P>0.05);观察组患儿各时间段疼痛程度评分均低于对照组,差异有统计学意义(P<0.05);两组患儿并发症发生风险相比,差异无统计学意义(P>0.05)。结论两种手术入路方式均可治疗先天性心脏病,且与胸骨正中切口相比,右腋下小切口不会影响患儿呼吸功能,且可改善疼痛程度,促进患儿快速康复,安全性较高,值得临床应用。 展开更多
关键词 先天性心脏病 心脏直视手术 右腋下小切口 胸骨正中切口
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象性合参论远志效用特色与优势 被引量:1
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作者 秦林 彭欣 《山东中医药大学学报》 2024年第2期144-149,共6页
采用药性与法象理论合参方法,融合现代药理与临床认识,阐释远志双调心神的作用机制,为远志治疗难治性病证提供药学与临床依据。研究发现,远志的特殊药象是其宁心安神功效的药材学基础,结合其“辛烈开窍”的性能特点,采用象性合参的方法... 采用药性与法象理论合参方法,融合现代药理与临床认识,阐释远志双调心神的作用机制,为远志治疗难治性病证提供药学与临床依据。研究发现,远志的特殊药象是其宁心安神功效的药材学基础,结合其“辛烈开窍”的性能特点,采用象性合参的方法,不仅有助于理解远志双调心神的特殊功效及其“安神不闭窍,开窍不动神”的药效特点,而且对认识用其治心神疾患、睡眠紊乱以及惊风、中风、癫痫等病证的作用优势,也提供了“象思维”的路径。象性合参还可揭示远志交通心肾的作用机制,并与其双调心神作用结合,拓展治疗心神失常之应用范围。因此,运用象性合参阐释远志的多重药理效用,是探析其治疗疑难杂病机制的重要方法。 展开更多
关键词 远志 法象药理 象性合参 安神开窍 双调心神 交通心肾
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胸骨正中劈开入路心脏术后并发胸部切口感染危险因素的病例对照研究
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作者 陈东升 刘建超 +6 位作者 冯泽坤 李双磊 何添 张广良 梁纯 陈犹白 韩岩 《解放军医学院学报》 CAS 2024年第3期245-251,共7页
背景胸骨正中劈开术是开胸心脏手术的常规入路,经此入路行心脏手术的患者术后可并发胸部切口感染(sternal wound infection,SWI),给患者造成巨大的心理和经济负担。目的探索SWI发生的危险因素,积极预防并降低其发病率。方法回顾性分析2... 背景胸骨正中劈开术是开胸心脏手术的常规入路,经此入路行心脏手术的患者术后可并发胸部切口感染(sternal wound infection,SWI),给患者造成巨大的心理和经济负担。目的探索SWI发生的危险因素,积极预防并降低其发病率。方法回顾性分析2011年1月—2021年1月于解放军总医院通过胸骨正中劈开入路行开胸心脏手术患者,筛选发生SWI的病例,并进行1∶4倾向性匹配。通过单因素Cox分析和LASSO回归筛选与SWI发生有关的特征指标,综合专家意见后进行多因素Cox回归确定切口感染的独立危险因素。结果5471例患者中61例在开胸手术后180 d内发生SWI,发病率为1.11%,其中44例为浅表胸骨切口感染,17例为深部胸骨切口感染。病例组男21例,女40例,中位年龄61岁;对照组男110例,女134例,中位年龄59岁。多因素Cox回归分析显示,体质量指数[HR(95%CI):1.07(1.00~1.14),P=0.038]、糖尿病[HR(95%CI):1.87(1.01~3.46),P=0.046]、心肌梗死[HR(95%CI):2.25(1.19~4.26),P=0.013]是SWI的独立危险因素。结论基于解放军总医院病例数据,本研究发现SWI的独立危险因素为糖尿病、高体质量指数和心肌梗死。这些因素可能通过破坏伤口愈合过程、损害组织修复和皮肤屏障完整性以及降低对细菌的抵抗力影响SWI的发生。 展开更多
关键词 胸部切口感染 伤口愈合 危险因素 前正中胸骨劈开术 心脏手术
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护士主导的心脏直视术后患者早期四级活动方案的构建
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作者 关亚萍 郑薇亮 +3 位作者 孙丽军 陈媛 丁洁莹 许佳佳 《护理学报》 2024年第22期67-72,共6页
目的构建护士主导的心脏直视术后患者早期四级活动方案。方法系统检索中国知网、万方、维普、PubMed、Medline、Cochrane Library数据库关于心脏直视术后患者早期活动的相关文献形成护士主导的心脏直视术后患者早期四级活动方案条目池;... 目的构建护士主导的心脏直视术后患者早期四级活动方案。方法系统检索中国知网、万方、维普、PubMed、Medline、Cochrane Library数据库关于心脏直视术后患者早期活动的相关文献形成护士主导的心脏直视术后患者早期四级活动方案条目池;然后通过专家小组会议对条目池进行修改形成方案的初稿;最后通过2轮德尔菲专家函询形成方案的终稿。结果2轮专家函询有效回收问卷分别为100%、93%;专家权威系数分别为0.900,0.930;肯德尔和谐系数分别为0.127、0.230,均具有统计学意义(P<0.001)。第2轮函询的变异系数为0~0.180,重要性评分为4.230~5.000,最终形成的护士主导的心脏直视术后患者早期四级活动方案包括3项一级指标、8项二级指标、27项三级指标。结论该研究构建的护士主导的心脏直视术后早期四级活动方案具有科学性与可行性,可为临床医护人员提供借鉴。 展开更多
关键词 护士主导 心脏直视术后 早期四级活动方案 德尔菲法
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手术室护理配合在婴幼儿患儿心脏直视手术中的应用效果探讨
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作者 张艳 《中国社区医师》 2024年第23期134-136,共3页
目的:探究婴幼儿患儿心脏直视手术中应用手术室护理配合的效果。方法:选择2020年7月—2022年7月泰安市妇幼保健院收治行心脏直视手术的婴幼儿患儿60例作为研究对象,以电脑随机形式分成对照组(30例)和观察组(30例)。其中对照组实施常规... 目的:探究婴幼儿患儿心脏直视手术中应用手术室护理配合的效果。方法:选择2020年7月—2022年7月泰安市妇幼保健院收治行心脏直视手术的婴幼儿患儿60例作为研究对象,以电脑随机形式分成对照组(30例)和观察组(30例)。其中对照组实施常规护理模式,观察组实施手术室护理配合模式,两组均连续随访3个月。比较两组患儿临床相关指标、肺功能、瘢痕及术后并发症发生率。结果:观察组患儿手术室停留时间、体外循环时间、主动脉阻断耗时均短于对照组(P<0.05)。观察组干预后肺动脉压力、气道阻力、静态肺顺应性、血小板计数、凝血酶原时间、激活全血凝固时间均优于对照组(P<0.05)。观察组干预后瘢痕评分低于对照组(P<0.05)。观察组患儿术后并发症发生率低于对照组(P<0.05)。结论:对婴幼儿患儿心脏直视手术中应用护理配合效果显著,其能够改善患儿临床相关指标,降低术后并发症发生率,预后良好。 展开更多
关键词 婴幼儿 心脏直视手术 护理配合
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