Effect of Mouth Opening Training Stick Combined with Oral Massage on Mouth Opening Difficulty in Head and Neck Cancer Patients after Treatment

Objective: To study the application effect of mouth-opening training sticks combined with oral massage on patients with mouth-opening difficulty after treatment for head and neck cancer. Methods: Using convenient sampling, 60 patients with mouth-opening difficulty after treatment for head and neck cancer admitted to the Oncology Department from February 2022 to October 2023 were selected for a 2-week exercise and nursing program. The patients were divided into a control group (February 1, 2022 to November 30, 2022) and an observation group (December 1, 2022 to October 31, 2023), with 30 patients in each group. The control group underwent routine mouth-opening functional exercises combined with cork for oral support training, while the observation group underwent routine mouth-opening functional exercises combined with oral massage and mouth-opening training sticks for oral support training. The mouth-opening degree, mouth-opening difficulty level, comfort level, compliance, and quality of life were observed in both groups. Results: Before the intervention, there were no statistically significant differences in mouth-opening degree and mouth-opening difficulty level between the two groups (P > 0.05). After the intervention, the mouth-opening degree, mouth-opening difficulty level, oral comfort level, compliance, and QLICP-HN scores in the observation group were all better than those in the control group, with statistically significant differences (P < 0.05). Conclusion: The combination of mouth-opening training sticks and oral massage with mouth-opening functional exercises can effectively improve the degree of mouth-opening difficulty, enhance oral comfort, increase compliance with mouth-opening exercises, and improve quality of life.

Personalization for Massive Product Innovation Using Open Architecture

Product innovation is creation of new concepts to plan and realize technological and functional details in the product to satisfy market and customer needs. One of the key drivers to product innovation is reactions of the product to users’ needs. Product innovation needs a cognitive design method based on needs of variant users for the product personalization. In this paper, an open concept is introduced to provide ways to meet user’s individual need in product lifespan. It is for industries to propose product concepts based on open sources, develop and support the product on the public capability. Using the open concept in the product architecture, called open?architecture product(OAP), can improve the product personalization leading to massive product innovation. To promote this promise of the OAP, effective methods are discussed for the OAP development. This paper introduces research on OAPs using adaptable design methods to meet product personalization. Adaptable design is based on the modular structure for product adaptability using function modules and adaptable interfaces. The proposed method provides solutions for planning modules and implementation of OAPs. Methods of OAP module planning, detail and interface design are described for transformation of product concepts into physical structures. A multiple?purpose electrical car is developed in a case study to show effectiveness of the proposed method.

Open-Innovation in the Electrical and Electronic Industries: Engineered Bio-Fluid Compositions Are Paving the Way, and Testing Therewith

Engineered Biofluids are paving the way to industrialized and specifically produced and tailored functional fluids such as coolant and dielectric, high purity traceable media, for the electrical and electronic industries. Dielectric fluid compositions are commonly used in electrical devices, particularly in transformers. These liquids have the aim to isolate the various conductive elements of the device and to limit the heating of the equipment during its operation;in order to minimize, or maintain at higher power, the size of the device and to increase the lifespan of it. Concomitantly a number of bio and traditional processing advancements are made associated with pioneering process technologies which are outlined within the prime context of this paper. Enzyme Engineering and Cocktailing add “A New Dimension to Softer Greener Chem-Bio Approaches” which are referenced beyond curiosity purpose. Some of them are possibly “revolutionary” more than evolutionary. Testing has to evolve accordingly to appreciate the challenges ahead in semi-extreme conditions which are relevant to climate changes as well. A significant part of this orientation work addresses and exemplifies these necessary testing innovations, likely adaptable to smart and responsive connecting, and further down the line bigger data role and learning machine evolutionary concepts. One other innovative part of this exploratory work, is the influence that such illustrative localized testing, with integrated sensors/induced-tracers, and online interpretation, may have on the smart grid developments;whereby production, transmission, distribution and consumption of energy can be made more reliable, more effective and more predictive and can also have an impact on the performance, reliability and sustainability of the equipment itself. Those technologies and associated testing can support environmental, technological and societal awareness;helping to revert some trends being climate changes, fossil fuel preservation and other planetary challenges to maintain the overall and localized fundamental equilibriums.

Clinical effect of laparoscopic radical resection of colorectal cancer based on propensity score matching

BACKGROUND The incidence of colorectal cancer(CRC)is increasing annually.Laparoscopic radical resection of CRC is a minimally invasive procedure preferred in clinical practice.AIM To investigate the clinical effect of laparoscopic radical resection of CRC on the basis of propensity score matching(PSM).METHODS The clinical data of 100 patients who received inpatient treatment for CRC at Changde Hospital,Xiangya School of Medicine,Central South University(The First People’s Hospital of Changde City)were analyzed retrospectively.The control group included patients who underwent open surgery(n=43),and those who underwent laparoscopic surgery formed the observation group(n=57).The baseline information of both groups was equipoised using 1×1 PSM.Differences in the perioperative parameters,inflammatory response,immune function,degree of pain,and physical status between the groups were analyzed.RESULTS Thirty patients from both groups were successfully matched.After PSM,baseline data showed no statistically significant differences between the groups:(1)Periop-erative parameters:The observation group had a longer surgery time,less intra-operative blood loss,earlier first ambulation and first anal exhaust times,and shorter gastric tube indwelling time than the control group;(2)Inflammatory response:24 h after surgery,the levels of interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α)between groups were higher than preoperatively.IL-6,CRP,and TNF-αlevels in the observation group were lower than in the control group;(3)Immune function:At 24 h after surgery,counts of CD4-positive T-lymphocytes(CD4+)and CD4+/CD8-positive T-lymphocytes(CD8+)in both groups were lower than those before surgery,whereas CD8+was higher than that before surgery.At 24 h after surgery,both CD4+counts and CD4+/CD8+in the observation group were higher than those in the control group,whereas CD8+counts were lower;(4)Degree of pain:The visual analog scale scores in the observation group were lower than those in the control group at 24 and 72 h after surgery;and(5)Physical status:One month after surgery,the Karnofsky performance score in the observation group was higher than that in the control group.CONCLUSION Laparoscopic radical resection of CRC has significant benefits,such as reducing postoperative pain and postoperative inflammatory response,avoiding excessive immune inhibition,and contributing to postoperative recovery.

New AI-IP-EI Trilogy Opens Innovation to New Dimensions;Another Chip in “the Innovation Wall”, What About Emotional Intelligence (EI)?

The red thread of the AI-IP-EI Trilogy fate of this study, may have the appearance of a pot-pourri of intellectual and intelligence natures, as a matter of fact that it emanates from the genesis and practical synergism of the trilogy components. Concretely: The paper goes from: AI (Artificial Intelligence)—to the related IP (Intellectual Property) domain—to the relevance of EI (Emotional Intelligence);thus, forming the new AI-IP-EI Trilogy and its attributes and specific impacts to the new innovation process, and business model dimensions. These impacts are outlined and illustrated in part in essays of specific sections and all along. Several concrete study cases are used in the various dedicated sections;such as cases respective to the inventor status, and the EI factor, to the sport education innovative dimension, as well as to biases as inevitably promoting and revealing, to drastically enlarge open innovation supported by constructivism and creations of musical group as a model of open reflexive education. Overall resulting adapted business models appear to have a massive potential, and a multidimensional reach with a necessary attention to the IP policy on going definition. The durable green dimension is exemplified as well. The Ethics-plus, “@LEAST?”, said corpus is proposed. Could a human centric, AI-adapted-IP policy, internationally embraced, take part to some level of arbitrage, normative and enduring reliability in the field of interest? This seems to be “en route”. Shall the EI (Emotional Intelligence) factor be supervised? Likely so. Is traditional open innovation renewed to a more comprehensive, more inclusive dimension reminding best business practice and now “beyond”? Definitely, and will remain an opportunity, all along the 4IR quantum game changer to come. Neither seeking an in-depth expert analysis, nor a grand public over-simplified bavardage, of the trilogy, AI-IP-EI, four authors here propose an illustrated view of scientific, educational, visionary, demonstrative value to the subject matter. They are aged about 30-40-50-60, being IP & Innovation strategist, future IP lawyer, children-teacher and professional academy sport coach, illustrator and bio-advanced materials engineering “Fellow Scientist”. With experience of large and smaller organizations, being involved innovators, inventors and private artists as well, they are sharing their “non-jargonized down-to-earth”, forward looking views through a structured analysis of the trilogy using realistic examples and data from rather diverse specialized independent sources, biotechnology, nanomaterials, sport… New invention and inventorship is been “reconceptualized” at least from an “insighter or insider” viewpoint, and sport team approach more broadly revisited from its academy level to its commercial asset impact, via educational virtues and values. Music group constructivism enters the scene as well with its exemplary reflexivity and alterity valued for open innovation. Science is the prime lead. “Emotional intelligence, EI, is still an emerging area within AI” and beyond? A new open innovation scheme is taking place. This prompted our intention to further contribute to this matter. Is EI, the tree gently challenging the wind? Generated by AI and IP streams and scientific applications therewith? Naturally. Conclusions are encouraging the follow-up of promising orientations underlined by the AI-IP-EI Trilogy, favoring human centric feature adoptions.

IP &Innovation, within the Context of Frontier Technologies;A Matter of Accessibility with “Open” Questions?

Through a series of duly cited, and quoted (“–”), excerpts, originating mostly from two Technology Trends reports, WIPO (2019), WIPO (2021), an attempt to establish a pseudo dialog is proposed, in order to surface a few questions accessible to a larger public of innovators, who may have an interest in the IP accessibility dimension using Frontier Technologies (such as AI, IoT, 3D…). AT, Assistive Technology, is instrumental as a uniquely faceted example. The illustrations’ section extends the consideration and integration of additional “traits” of the field of interest and related. Intuitive answers are “reachable” and further literature is provided on the relevant matters and connected. The emphasis is on educational, illustrative and demonstrative value.

基于CAPE-OPEN标准的简捷炼油过程建模及常减压蒸馏流程在线模拟

简捷炼油过程模型广泛应用于运行监测、在线计算、实时优化等领域,但大多数模型只是将输入、输出变量进行关联,无法计算出各组分流量组成,难以集成在模拟软件中进行全流程模拟。本研究简化了炼油分离过程,开发了基于CAPE-OPEN标准的简捷炼油塔模型。首先,将炼油过程简化为连续的分离单元,根据实际产品数据校正模型参数,实现某一实际工况流程模拟;其次,将模型参数与实际工况操作变量数据相结合,采用径向基函数插值确定操作变量对模型参数的影响关系,实现多种工况流程模拟;最后,通过常减压蒸馏工业装置实例的3种工况进行验证。结果表明:各工况模拟结果与Aspen计算结果相比,初馏塔塔顶油馏出温度点偏差大多在2%以内,常减压蒸馏塔各侧线油的馏出温度点平均偏差在3%以内;与实际结果相比,平均误差都在5%以内,符合工程允许误差范围要求。所建模型的计算速度快,各塔均在0.2 s左右完成计算,适用于在线生产、调度等。

我国高质量教育资源供给机制创新与路径研究——来自美国“#GoOpen”计划的启示

数字化是当下教育改革的重点,也是未来教育发展的趋势。无论是作为“十四五”规划中的战略举措,还是党的二十大中提出的必然要求,构建数字化教育资源为主体的高质量教育资源体系在当下具有必要性与迫切性。美国#GoOpen计划自实施以来,在教育资源数字化、个性化、均等化三个方面均取得了一定成果。通过对该计划官方文件与政策进行解读,对其内涵与特点进行分析,我国在进行高质量教育资源建设及其供给路径探究过程中应当重视统筹规划,循序渐进,同时完善多重考核与评估机制,结合社会多方力量,保证每个学习者的享有权利,最终走向教育公平,共同发展。

Market capitalization shock effects on open innovation models in e‑commerce:golden cut q‑rung orthopair fuzzy multicriteria decision‑making analysis

This research paper analyzes revenue trends in e-commerce,a sector with an annual sales volume of more than 340 billion dollars.The article evaluates,despite a scarcity of data,the effects on e-commerce development of the ubiquitous lockdowns and restriction measures introduced by most countries during the pandemic period.The analysis covers monthly data from January 1996 to February 2021.The research paper analyzes relative changes in the original time series through the autocorrelation function.The objects of this analysis are Amazon and Alibaba,as they are benchmarks in the e-commerce industry.This paper tests the shock effect on the e-commerce companies Alibaba in China and Amazon in the USA,concluding that it is weaker for companies with small market capitalizations.As a result,the effect on estimated e-trade volume in the USA was approximately 35%in 2020.Another evaluation considers fuzzy decision-making methodology.For this purpose,balanced scorecard-based open financial innovation models for the e-commerce industry are weighted with multistepwise weight assessment ratio analysis based on q-rung orthopair fuzzy sets and the golden cut.Within this framework,a detailed analysis of competitors should be made.The paper proves that this situation positively affects the development of successful financial innovation models for the e-commerce industry.Therefore,it may be possible to attract greater attention from e-commerce companies for these financial innovation products.

The Evolution of China’s National Innovation System During the 40 Years of Reform and Opening Up

From the perspective of economic system transformations and scientific and technological system reforms, this paper investigates the evolution of China’s national innovation system (NIS) during the 40 years of reform and opening up. It concludes that China’s NIS has evolved from weak to strong, from a follower groping its way onto the track of independent innovation with Chinese characteristics. China’s innovation system has experienced a trajectory from “introduction and imitation of complete sets of technology” to “market for technology and imitative innovation,” to “integrated and secondary innovation” and on to “integrated, secondary, collaborative and original innovation combined.” The path of independent innovation with Chinese characteristics is a natural choice of economic, societal, and technological development in the new era.

Open Innovation： A Systematic Literature Analysis

What is open innovation？ There are different definitions of open innovation, depending, at least, on three parameters： source, ownership, or users of the knowledge linked to innovation. The aim of the paper is to make a systematic literature review, to map open innovation studies, and to re-conceptualize the openness according to two dimensions： degree of technology convergence and ontology of openness. In particular, we propose a classification of open innovation, based on the distinction between the originator/developer of the knowledge and the user. Users are a ubiquitous category, because they can be originators, as well as customers of the innovation itself. Therefore, we point out that there are three types of open innovation, whose degree of openness is defined according to an ontological dimension： at users’ level, at an industry level, and among different fields or industries. Firm’s structure affects the propensity to open innovation adoption; and the type of innovation itself. Finally, we identify another literature gap： the relationship between the open innovation model and grand challenge. Even if open innovation seems to be ideally connected to grand challenges and many industries actually adopt this model, there seems to emerge a gap in literature. Therefore, we propose a conceptual model for future researches.

Inheritance and Innovation of Xi Jinping’s Theory and Practice of Opening Up

Adherence to China’s fundamental national policy of opening up is the only means of developing socialism that incorporates Chinese characteristics.General Secretary Xi Jinping has proposed the construction of a global community with a shared future,explaining the conceptual significance of engaging with the outside world.He has emphasized the importance of following the path of peaceful development and abiding by a mutually beneficial win-win strategy to unlock the country.He has postulated the Belt and Road Initiative and sought international cooperation,laying a robust material foundation to promote increasingly accessible relations between China and other nations worldwide.He has further illuminated the practical value of opening up.Xi Jinping’s conception of opening up represents the inheritance and innovation of a theory of world history and the conceptual and functional significance of unlocking the nation in the manner of Marx,Engels,and Deng Xiaoping.China’s strategy of opening up in the new era is marked by the idea of harmony but not uniformity.This policy was founded on innovation and development,based on China’s achievements through 40 years of reform.

Leveraging Digital Entrepreneurship Through Collaboration Between Incumbent Firms and Entrepreneurial Ventures： An Inbound Open Innovation Perspective

Considering that traditional research and development （R＆D） models cannot keep up with the disruptive advances, the incumbent firms should consider external sources for obtaining and commercializing digital innovations. By contrast, entrepreneurial ventures have the necessary tech development skills and agility to create digital innovations. There has never been a better time for incumbent firms and entrepreneurial ventures to collaborate One paradigm that establishes such mutual beneficial partnership is called ＂inbound open innovation＂. Based on a multiple-cases design, this research provides evidence of the benefits, the degree of co-creation required, and the various collaboration schemes that emerge through an open innovation initiative

Adhering to Opening and Innovation,Building A First-Class Yangzhou

Located in central Jiangsu Prov- ince,Yangzhou is situated north of the Yangtze River and south of the Huai River.The Beijing- Hangzhou Grand Canal runs down from the north,right through the center of Yangzhou,and continues due south.

Open Innovation and New Mechanism of Market-Based Technology Diffusion from MNCs

The international community has blamed developing countries for the lack of intellectual property rights(IPR)protection-not least the“forced technology transfers”-in attracting foreign direct investment(FDI).This paper employs the largesample contract data of multinational companies’(MNCs)IT R&D transactions in China to discuss this controversy from a unique perspective of MNCs in the role of contractors.Our findings suggest that MNCs initially guarded their know-how before the 2000s under closed innovation,but have started to take the initiative to transfer technology to local partners as open innovation held sway.China’s structured market entities and huge demand for technology transactions have served as key drivers for MNCs to transfer technology,which has been further boosted by the new business model of open innovation.This paper’s empirical analysis not only helps unravel the“black box”of technology transfers by MNCs,but reveals how late-moving developing countries may make better use of FDI referencing China’s experience on the three dimensions of market opportunities,structured entities,and economies of scale.

Innovation of Chinese Discourse in the Context of Reform and Opening Up

Through reform and opening up,China has moved from the edge of the world arena to the center and this great historical change in its development has created new requirements for the innovation of Chinese discourse.The remarkable achievements of reform and opening up have not only maintained the vitality of Chinese discourse,but also built the inherent foundation for holding confidence in discourse.The key reason why the policy of reform and opening up has facilitated the historic construction of Chinese discourse is that it is a scientific answer to the questions of our times about how to build socialism in a country relatively backward in the level of economy and education.In a new era for the cause of socialism with Chinese characteristics,the innovations and development of Chinese discourse have shown new features rarely seen before,among which the most significant is that constructing Chinese discourse is no longer a matter of individual cases but more of a common phenomenon.In the historic journey towards an all-round in-depth reform,broader theoretical space has been created for Chinese discourse.In addition,it is an important signpost in the path of promoting innovative development of Chinese discourse in a new era,namely,how to"tell China’s stories well",and establish an appropriate mode for conveying Chinese discourse to the world.

Inbound Open Innovation, Business Model Design and Firm Innovation Performance

Through systematic literature review,this study constructs a relationship model of the impact of inbound open innovation on firm innovation performance,and introduced two-dimensional business model design(novelty and efficiency)as mediation variables.It is preliminary confirmed theoretically that inbound open innovation has a positive impact on firm innovation performance,and the rationality of business model playing a mediation role in the relationship between inbound open innovation and innovation performance.Through questionnaire survey and empirical analysis,it is concluded that inbound open innovation has a positive impact on firm innovation performance;Two-dimensional business model design(novelty and efficiency)play a completely positive mediation role in the relationship between inbound open innovation and innovation performance.Based on these findings,this paper developed recommendations for future research.

HAVING FULL UNDERSTANDING OF THE TIMES, COMPLYING WITH THE TREND, STANDING FAST AND MAKING INNOVATIONS: ON CHINA'S DIPLOMACY IN FOUR DECADES OF REFORM AND OPENING-UP

The year 1978 was destined to be an extraordinary year in contemporary Chinese history,which witnessed the convening of the grd Plenary Session of the iuth National Congress of the Communist Party of China,the adoption of reform and opening up policy and setting of new journey of China's diplomacy.

Artificial Self-Recovery Opens up a New Journey of Autonomous Health of Mechanical Equipments

1.Introduction With the implementation of modern production strategies,such as“Industry 4.0”and“Made in China 2025,”the development of high-end mechanical equipment is gradually reaching a high degree of parameterization,digitalization,networking,and intelligence[1].High-end mechanical equipment no longer consists of traditional single devices,but is closely linked to the overall production process;that is,a variety of devices interact with each other and collectively form a complex system.However,faults can lead to production delays throughout the system and even seriously threaten the safety of workers[2].In addition,equipment operating in unmanned air or space vehicles(including space robots)cannot be repaired by humans if they break down[3].Until recently,the typical method of addressing machine faults was primarily the“fault cure”method,which involves manually shutting down,inspecting,and repairing the equipment to restore normal operation.Accordingly,the maintenance cycle of the traditional“fault cure”method is time-consuming,and the quality of the maintenance depends on the skills of the technician[4].