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基于CAPE-OPEN标准的简捷炼油过程建模及常减压蒸馏流程在线模拟
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作者 焦云强 陈玉石 王建平 《石油炼制与化工》 CAS CSCD 北大核心 2024年第8期164-177,共14页
简捷炼油过程模型广泛应用于运行监测、在线计算、实时优化等领域,但大多数模型只是将输入、输出变量进行关联,无法计算出各组分流量组成,难以集成在模拟软件中进行全流程模拟。本研究简化了炼油分离过程,开发了基于CAPE-OPEN标准的简... 简捷炼油过程模型广泛应用于运行监测、在线计算、实时优化等领域,但大多数模型只是将输入、输出变量进行关联,无法计算出各组分流量组成,难以集成在模拟软件中进行全流程模拟。本研究简化了炼油分离过程,开发了基于CAPE-OPEN标准的简捷炼油塔模型。首先,将炼油过程简化为连续的分离单元,根据实际产品数据校正模型参数,实现某一实际工况流程模拟;其次,将模型参数与实际工况操作变量数据相结合,采用径向基函数插值确定操作变量对模型参数的影响关系,实现多种工况流程模拟;最后,通过常减压蒸馏工业装置实例的3种工况进行验证。结果表明:各工况模拟结果与Aspen计算结果相比,初馏塔塔顶油馏出温度点偏差大多在2%以内,常减压蒸馏塔各侧线油的馏出温度点平均偏差在3%以内;与实际结果相比,平均误差都在5%以内,符合工程允许误差范围要求。所建模型的计算速度快,各塔均在0.2 s左右完成计算,适用于在线生产、调度等。 展开更多
关键词 简捷炼油模型 过程建模 CAPE-open 在线模拟计算 常减压蒸馏装置
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我国高质量教育资源供给机制创新与路径研究——来自美国“#GoOpen”计划的启示
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作者 刘和海 屈昊 《中国电化教育》 北大核心 2024年第2期69-78,99,共11页
数字化是当下教育改革的重点,也是未来教育发展的趋势。无论是作为“十四五”规划中的战略举措,还是党的二十大中提出的必然要求,构建数字化教育资源为主体的高质量教育资源体系在当下具有必要性与迫切性。美国#GoOpen计划自实施以来,... 数字化是当下教育改革的重点,也是未来教育发展的趋势。无论是作为“十四五”规划中的战略举措,还是党的二十大中提出的必然要求,构建数字化教育资源为主体的高质量教育资源体系在当下具有必要性与迫切性。美国#GoOpen计划自实施以来,在教育资源数字化、个性化、均等化三个方面均取得了一定成果。通过对该计划官方文件与政策进行解读,对其内涵与特点进行分析,我国在进行高质量教育资源建设及其供给路径探究过程中应当重视统筹规划,循序渐进,同时完善多重考核与评估机制,结合社会多方力量,保证每个学习者的享有权利,最终走向教育公平,共同发展。 展开更多
关键词 #Goopen 开放教育资源 高质量教育资源 供给路径
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基于YOLO-OpenMax的水声通信信号开集识别方法
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作者 李杰 李勇斌 +2 位作者 郑娄 王彬 黄焱 《信息工程大学学报》 2024年第3期258-264,271,共8页
水声通信信号调制方式随着技术进步从典型的传统调制方式发展为水声通信机厂商私有开发的新型调制方式,这使得现有的水声通信信号闭集调制识别技术实用性受到制约,但现阶段鲜有研究基于深度学习的水声通信信号调制方式的开集识别方法。... 水声通信信号调制方式随着技术进步从典型的传统调制方式发展为水声通信机厂商私有开发的新型调制方式,这使得现有的水声通信信号闭集调制识别技术实用性受到制约,但现阶段鲜有研究基于深度学习的水声通信信号调制方式的开集识别方法。针对此现状,提出一种基于YOLO图像检测识别网络和OpenMax模型的开集识别方法。利用YOLOv5网络的输出特点,将传统OpenMax模型的处理方法进行改进,提出一种两步测试方法,实现了在多径信道下的水声通信信号的开集识别。仿真实验表明:在归一化系数为0.5,信噪比等于10 dB条件下的归一化开集识别准确率达到90%以上,实测数据同样验证了本文方法的有效性。 展开更多
关键词 水声通信 调制方式识别 开集识别 两步测试流程
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Effect of Mouth Opening Training Stick Combined with Oral Massage on Mouth Opening Difficulty in Head and Neck Cancer Patients after Treatment
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作者 Jinhua Liu Qiong Wen 《Journal of Biosciences and Medicines》 2024年第6期43-51,共9页
Objective: To study the application effect of mouth-opening training sticks combined with oral massage on patients with mouth-opening difficulty after treatment for head and neck cancer. Methods: Using convenient samp... Objective: To study the application effect of mouth-opening training sticks combined with oral massage on patients with mouth-opening difficulty after treatment for head and neck cancer. Methods: Using convenient sampling, 60 patients with mouth-opening difficulty after treatment for head and neck cancer admitted to the Oncology Department from February 2022 to October 2023 were selected for a 2-week exercise and nursing program. The patients were divided into a control group (February 1, 2022 to November 30, 2022) and an observation group (December 1, 2022 to October 31, 2023), with 30 patients in each group. The control group underwent routine mouth-opening functional exercises combined with cork for oral support training, while the observation group underwent routine mouth-opening functional exercises combined with oral massage and mouth-opening training sticks for oral support training. The mouth-opening degree, mouth-opening difficulty level, comfort level, compliance, and quality of life were observed in both groups. Results: Before the intervention, there were no statistically significant differences in mouth-opening degree and mouth-opening difficulty level between the two groups (P > 0.05). After the intervention, the mouth-opening degree, mouth-opening difficulty level, oral comfort level, compliance, and QLICP-HN scores in the observation group were all better than those in the control group, with statistically significant differences (P < 0.05). Conclusion: The combination of mouth-opening training sticks and oral massage with mouth-opening functional exercises can effectively improve the degree of mouth-opening difficulty, enhance oral comfort, increase compliance with mouth-opening exercises, and improve quality of life. 展开更多
关键词 Head and Neck Cancer Difficulty in opening the Mouth open Mouth Training Stick Oral Massage Rehabilitation Effect
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OpenAI发布首个文生视频模型Sora 被引量:1
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《电器》 2024年第3期63-63,共1页
2024年2月16日,OpenAI发布首个文生视频模型Sora。Sora模型可以通过文本描述生成60秒长视频,还可以对视频色彩风格等要素精确理解,创造出人物表情丰富、情感生动的视频内容。据介绍,Sora模型有三大突出亮点,实现了AIGC领域的里程碑式进展。
关键词 文本描述 open 表情丰富 色彩风格 视频 AI 突出亮点
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A chaotic hierarchical encryption/watermark embedding scheme for multi-medical images based on row-column confusion and closed-loop bi-directional diffusion
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作者 张哲祎 牟俊 +1 位作者 Santo Banerjee 曹颖鸿 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期228-237,共10页
Security during remote transmission has been an important concern for researchers in recent years.In this paper,a hierarchical encryption multi-image encryption scheme for people with different security levels is desi... Security during remote transmission has been an important concern for researchers in recent years.In this paper,a hierarchical encryption multi-image encryption scheme for people with different security levels is designed,and a multiimage encryption(MIE)algorithm with row and column confusion and closed-loop bi-directional diffusion is adopted in the paper.While ensuring secure communication of medical image information,people with different security levels have different levels of decryption keys,and differentiated visual effects can be obtained by using the strong sensitivity of chaotic keys.The highest security level can obtain decrypted images without watermarks,and at the same time,patient information and copyright attribution can be verified by obtaining watermark images.The experimental results show that the scheme is sufficiently secure as an MIE scheme with visualized differences and the encryption and decryption efficiency is significantly improved compared to other works. 展开更多
关键词 chaotic hierarchical encryption multi-medical image encryption differentiated visual effects row-column confusion closed-loop bi-directional diffusion transform domain watermark embedding
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Open-Source Software Defined Networking Controllers:State-of-the-Art,Challenges and Solutions for Future Network Providers
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作者 Johari Abdul Rahim Rosdiadee Nordin Oluwatosin Ahmed Amodu 《Computers, Materials & Continua》 SCIE EI 2024年第7期747-800,共54页
Software Defined Networking(SDN)is programmable by separation of forwarding control through the centralization of the controller.The controller plays the role of the‘brain’that dictates the intelligent part of SDN t... Software Defined Networking(SDN)is programmable by separation of forwarding control through the centralization of the controller.The controller plays the role of the‘brain’that dictates the intelligent part of SDN technology.Various versions of SDN controllers exist as a response to the diverse demands and functions expected of them.There are several SDN controllers available in the open market besides a large number of commercial controllers;some are developed tomeet carrier-grade service levels and one of the recent trends in open-source SDN controllers is the Open Network Operating System(ONOS).This paper presents a comparative study between open source SDN controllers,which are known as Network Controller Platform(NOX),Python-based Network Controller(POX),component-based SDN framework(Ryu),Java-based OpenFlow controller(Floodlight),OpenDayLight(ODL)and ONOS.The discussion is further extended into ONOS architecture,as well as,the evolution of ONOS controllers.This article will review use cases based on ONOS controllers in several application deployments.Moreover,the opportunities and challenges of open source SDN controllers will be discussed,exploring carriergrade ONOS for future real-world deployments,ONOS unique features and identifying the suitable choice of SDN controller for service providers.In addition,we attempt to provide answers to several critical questions relating to the implications of the open-source nature of SDN controllers regarding vendor lock-in,interoperability,and standards compliance,Similarly,real-world use cases of organizations using open-source SDN are highlighted and how the open-source community contributes to the development of SDN controllers.Furthermore,challenges faced by open-source projects,and considerations when choosing an open-source SDN controller are underscored.Then the role of Artificial Intelligence(AI)and Machine Learning(ML)in the evolution of open-source SDN controllers in light of recent research is indicated.In addition,the challenges and limitations associated with deploying open-source SDN controllers in production networks,how can they be mitigated,and finally how opensource SDN controllers handle network security and ensure that network configurations and policies are robust and resilient are presented.Potential opportunities and challenges for future Open SDN deployment are outlined to conclude the article. 展开更多
关键词 ONOS open source software SDN software defined networking
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Atomically Dispersed Ruthenium Catalysts with Open Hollow Structure for Lithium-Oxygen Batteries
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作者 Xin Chen Yu Zhang +5 位作者 Chang Chen Huinan Li Yuran Lin Ke Yu Caiyun Nan Chen Chen 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第2期154-164,共11页
Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult... Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult decomposition of discharge products at present.Here,we have developed N-doped carbon anchored atomically dispersed Ru sites cathode catalyst with open hollow structure(h-RuNC)for Lithium–oxygen battery.On one hand,the abundance of atomically dispersed Ru sites can effectively catalyze the formation and decomposition of discharge products,thereby greatly enhancing the redox kinetics.On the other hand,the open hollow structure not only enhances the mass activity of atomically dispersed Ru sites but also improves the diffusion efficiency of catalytic molecules.Therefore,the excellent activity from atomically dispersed Ru sites and the enhanced diffusion from open hollow structure respectively improve the redox kinetics and cycling stability,ultimately achieving a high-performance lithium–oxygen battery. 展开更多
关键词 Atomically dispersed open hollow structure Discharge product LITHIUM Oxygen battery
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基于Open CASCADE的拱桥建模研究
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作者 黄飞 《铁路技术创新》 2024年第2期63-70,共8页
几何引擎是三维BIM建模软件中的核心组件,对软件的性能、准确性、互操作性和用户体验等方面有着重要影响。商业软件的几何引擎虽然经过了多年的发展和优化具有较好的性能和稳定性,但常受限于软件厂商提供的API接口和商业软件所需要的系... 几何引擎是三维BIM建模软件中的核心组件,对软件的性能、准确性、互操作性和用户体验等方面有着重要影响。商业软件的几何引擎虽然经过了多年的发展和优化具有较好的性能和稳定性,但常受限于软件厂商提供的API接口和商业软件所需要的系统环境,无法对底层数据进行访问或修改,灵活性较差,且不具备完全自主商业版权。基于开源几何引擎的应用在很多领域已有相关的研究成果,但在桥梁工程领域较少,基于开源几何引擎Open CASCADE对桥梁工程领域的模型构建技术进行探索,实现自主可控的桥梁工程三维建模平台,以拱桥为研究对象,结合几何引擎的模型构建技术,实现拱桥模型的创建。探索开源几何引擎在桥梁工程领域的建模实现能力,为实现更多桥型的三维建模以及基于模型更进一步的衍生应用积累经验,并为打造自主可控的桥梁工程建模软件提供参考。 展开更多
关键词 桥梁工程 BIM 开源几何引擎 open CASCADE 拱桥建模 自主可控
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The Effect of Uterine Artery Occlusion with Tourniquet on Ovarian Reserve during Open Myomectomy at a University Teaching Hospital in Southern Nigeria
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作者 William Amebeobari Mube Justina Omoikhefe Alegbeleye Ngozi Clare Orazulike 《Advances in Reproductive Sciences》 CAS 2024年第1期37-50,共14页
Background: The most common surgical treatment for symptomatic uterine fibroids, particularly in women with fertility concerns, is open myomectomy. Given the high vascularity of the uterus, haemorrhage during the proc... Background: The most common surgical treatment for symptomatic uterine fibroids, particularly in women with fertility concerns, is open myomectomy. Given the high vascularity of the uterus, haemorrhage during the procedure is a serious risk that is often mitigated with a uterine tourniquet. Aim and Objectives: To evaluate the effect of uterine artery occlusion with a tourniquet during open myomectomy on ovarian reserve using serial anti-Mullerian hormone (AMH) measurements. Materials and Methods: This was a prospective longitudinal study with a quasi-experimental design and a convenient sampling technique. The study enrolled 47 women who had abdominal myomectomy between September 1, 2021, and March 31, 2022, at the University of Port Harcourt Teaching Hospital. Blood samples were collected before anaesthesia was administered in theatre, on day two, and three months after open abdominal myomectomy for anti-Mullerian hormone assay. The data was collected using a semi-structured proforma, entered into an Excel spreadsheet, and analyzed using SPSS version 25.0 with a 95% confidence interval. Statistical significance level was set at 0.05. Results: The pre-surgery AMH mean value was 1.67 ± 1.44 ng/ml, while the values after using a uterine tourniquet at myomectomy on the second day and three months later were 1.22 ± 1.24 ng/ml and 1.59 ± 1.43 ng/ml, respectively. There was no statistically significant change in AMH levels, and there was no statistically significant relationship between blood loss and tourniquet time and AMH after open abdominal myomectomy. Conclusion: The use of a uterine tourniquet and blood loss during open myomectomy has no effect on ovarian reserve. 展开更多
关键词 Uterine Tourniquet open Abdominal Myomectomy Ovarian Reserve Anti-Mullerian Hormone NIGERIA
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A comparative study on characteristics of retracted publications across different open access levels
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作者 Er-Te Zheng Hui-Zhen Fu 《Journal of Data and Information Science》 CSCD 2024年第2期22-40,共19页
Purpose:Recently,global science has shown an increasing open trend,however,the characteristics of research integrity of open access(OA)publications have rarely been studied.The aim of this study is to compare the char... Purpose:Recently,global science has shown an increasing open trend,however,the characteristics of research integrity of open access(OA)publications have rarely been studied.The aim of this study is to compare the characteristics of retracted articles across different OA levels and discover whether OA level influences the characteristics of retracted articles.Design/methodology/approach:The research conducted an analysis of 6,005 retracted publications between 2001 and 2020 from the Web of Science and Retraction Watch databases.These publications were categorized based on their OA levels,including Gold OA,Green OA,and non-OA.The study explored retraction rates,time lags and reasons within these categories.Findings:The findings of this research revealed distinct patterns in retraction rates among different OA levels.Publications with Gold OA demonstrated the highest retraction rate,followed by Green OA and non-OA.A comparison of retraction reasons between Gold OA and non-OA categories indicated similar proportions,while Green OA exhibited a higher proportion due to falsification and manipulation issues,along with a lower occurrence of plagiarism and authorship issues.The retraction time lag was shortest for Gold OA,followed by non-OA,and longest for Green OA.The prolonged retraction time for Green OA could be attributed to an atypical distribution of retraction reasons.A comparative study on characteristics of retracted publications across different open access levels Research limitations:There is no exploration of a wider range of OA levels,such as Hybrid OA and Bronze OA.Practical implications:The outcomes of this study suggest the need for increased attention to research integrity within the OA publications.The occurrences offalsification,manipulation,and ethical concerns within Green OA publications warrant attention from the scientific community.Originality/value:This study contributes to the understanding of research integrity in the realm of OA publications,shedding light on retraction patterns and reasons across different OA levels. 展开更多
关键词 open access Retracted publications Reasons for retraction Retraction time lag BIBLIOMETRICS
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Spatial Distribution Feature Extraction Network for Open Set Recognition of Electromagnetic Signal
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作者 Hui Zhang Huaji Zhou +1 位作者 Li Wang Feng Zhou 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期279-296,共18页
This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distri... This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distribution feature extraction layer in SDFEN replaces convolutional output neural networks with the spatial distribution features that focus more on inter-sample information by incorporating class center vectors.The designed hybrid loss function considers both intra-class distance and inter-class distance,thereby enhancing the similarity among samples of the same class and increasing the dissimilarity between samples of different classes during training.Consequently,this method allows unknown classes to occupy a larger space in the feature space.This reduces the possibility of overlap with known class samples and makes the boundaries between known and unknown samples more distinct.Additionally,the feature comparator threshold can be used to reject unknown samples.For signal open set recognition,seven methods,including the proposed method,are applied to two kinds of electromagnetic signal data:modulation signal and real-world emitter.The experimental results demonstrate that the proposed method outperforms the other six methods overall in a simulated open environment.Specifically,compared to the state-of-the-art Openmax method,the novel method achieves up to 8.87%and 5.25%higher micro-F-measures,respectively. 展开更多
关键词 Electromagnetic signal recognition deep learning feature extraction open set recognition
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A highly sensitive fluorescent probe RN-NA reveals peroxynitrite as a novel biomarker for primary open angle glaucoma
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作者 Bo Qin Yuan Lei +3 位作者 Luo Bao You-Jia Zhang Ke-Yin Liu Yu-Hong Chen 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第2期219-227,共9页
AIM:To directly quantify peroxynitrite(ONOO-)using a highly sensitive fluorescence resonance energy transfer probe RN-NA,investigate the association between ONOOand primary open angle glaucoma(POAG),and clarify whethe... AIM:To directly quantify peroxynitrite(ONOO-)using a highly sensitive fluorescence resonance energy transfer probe RN-NA,investigate the association between ONOOand primary open angle glaucoma(POAG),and clarify whether RN-NA could be used as a potential tool for POAG diagnosis.METHODS:Plasma and aqueous humor(AH)samples were collected from POAG patients(n=100,age:59.70±6.87y)and age-related cataract(ARC)patients(n=100,age:61.15±4.60y)admitted to our hospital.Next,RN-NA was used to detect ONOO-in plasma and AH samples,and the relationship between ONOO-level and POAG was analyzed using binary logistic regression.Besides,Pearson correlation analysis was applied to characterize the correlation of the levels of ONOO-with the patients’age,intraocular pressure(IOP),and mean deviation of visual field testing.The ONOO-scavenger MnTMPyP was employed to treat the 3-morpholinosyndnomine(SIN-1)-induced ocular hypertension in mice(n=7,6-8wk).Finally,the IOP and ONOO-in both eyes were measured 30min after the last drug treatment.RESULTS:ONOO-levels of AH and plasma were significantly higher in the POAG group than in the ARC group(P<0.01).Additionally,ONOO-levels were closely correlated with POAG in a binary logistic regression analysis[odds ratio(OR)=1.008,95%confidence interval(CI):1.002-1.013,P<0.01 for AH;OR=1.004,95%CI:1.002-1.006,P<0.001 for plasma].Pearson correlation analysis showed that ONOO-levels in AH or plasma were positively associated with visual field defects(R=0.51,P<0.01 for AH;R=0.45,P<0.001 for plasma),and ONOO-levels in plasma and AH were correlated in the POAG group(R=0.69,P<0.001).However,administering MnTMPyP to mouse eyes reversed the elevated IOP caused by SIN-1(P<0.05).CONCLUSION:ONOO-levels in AH and plasma,detected by RN-NA,are significantly related to POAG and positively correlated with visual field defects in POAG patients.Hence,ONOO-is a potential biomarker of POAG,especially advanced POAG.Besides,anti-nitration compounds may be novel ocular hypotensive agents based on the animal study. 展开更多
关键词 PEROXYNITRITE fluorescent probe RN-NA primary open angle glaucoma 3-morpholinosyndnomine
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Understanding the correlation between energy-state mismatching and open-circuit voltage loss in bulk heterojunction solar cells
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作者 Hyun-Seock Yang Danbi Kim +7 位作者 Chang-Mok Oh Vellaiappillai Tamilavan Pesi MHangoma Hojun Yi Bo RLee Insoo Shin In-Wook Hwang Sung Heum Park 《Carbon Energy》 SCIE EI CAS CSCD 2024年第5期164-174,共11页
Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires ener... Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires energy-state matching between the donor and acceptor at the BHJ interfaces.Thus,both geometrically and energetically accessible delocalized state matching at the hot energy level is crucial for achieving efficient PICT.In this study,an effective method for quantifying the hot state matching of OPVs was developed.The degree of energy-state matching between the electron donor and acceptor at BHJ interfaces was quantified using a mismatching factor(MF)calculated from the modified optical density of the BHJ.Furthermore,the correlation between the open-circuit voltage(Voc)of the OPV device and energy-state matching at the BHJ interface was investigated using the calculated MF.The OPVs with small absolute MF values exhibited high Voc values.This result clearly indicates that the energy-state matching between the donor and acceptor is crucial for achieving a high Voc in OPVs.Because the MF indicates the degree of energy-state matching,which is a critical factor for suppressing energy loss,it can be used to estimate the Voc loss in OPVs. 展开更多
关键词 bulk heterojunction open circuit voltage organic photovoltaics photoinduced charge transfer voltage loss
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HiLog:OpenHarmony的高性能日志系统
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作者 吴圣垚 王枫 +4 位作者 武延军 凌祥 屈晟 罗天悦 吴敬征 《软件学报》 EI CSCD 北大核心 2024年第4期2055-2075,共21页
日志是计算机系统中记录事件状态信息的的重要载体,日志系统负责计算机系统的日志生成、收集和输出.OpenHarmony是新兴的、面向全设备、全场景的开源操作系统.在所述工作之前,包括日志系统在内OpenHarmony有许多关键子系统尚未构建,而Op... 日志是计算机系统中记录事件状态信息的的重要载体,日志系统负责计算机系统的日志生成、收集和输出.OpenHarmony是新兴的、面向全设备、全场景的开源操作系统.在所述工作之前,包括日志系统在内OpenHarmony有许多关键子系统尚未构建,而OpenHarmony的开源特性使第三方开发者可以为其贡献核心代码.为了解决Open Harmony日志系统缺乏的问题,主要开展如下工作:(1)分析当今主流日志系统的技术架构和优缺点;(2)基于OpenHarmony操作系统的异构设备互联特性设计HiLog日志系统模型规范;(3)设计并实现第1个面向OpenHarmony的日志系统HiLog,并贡献到OpenHarmony主线;(4)对HiLog日志系统的关键指标进行测试和对比试验.实验数据表明,在基础性能方面,HiLog和Log的日志写入阶段吞吐量分别为1500 KB/s和700 KB/s,相比Android日志系统吞吐量提升114%;在日志持久化方面,HiLog可以3.5%的压缩率进行持久化,并且丢包率小于6‰,远低于Log.此外,HiLog还具备数据安全、流量控制等新型实用能力. 展开更多
关键词 操作系统 日志系统 开源软件 数据安全 流量控制
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Evaluation of hybrid closed-loop insulin delivery system in type 1 diabetes in real-world clinical practice:One-year observational study
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作者 Ahmed Eldib Shilton Dhaver +8 位作者 Karim Kibaa Astrid Atakov-Castillo Tareq Salah Marwa Al-Badri Abdelrahman Khater Ryan McCarragher Omnia Elenani Elena Toschi Osama Hamdy 《World Journal of Diabetes》 SCIE 2024年第3期455-462,共8页
BACKGROUND In 2016,the Food and Drug Administration approved the first hybrid closed-loop(HCL)insulin delivery system for adults with type 1 diabetes(T1D).There is limited information on the impact of using HCL system... BACKGROUND In 2016,the Food and Drug Administration approved the first hybrid closed-loop(HCL)insulin delivery system for adults with type 1 diabetes(T1D).There is limited information on the impact of using HCL systems on patient-reported outcomes(PROs)in patients with T1D in real-world clinical practice.In this independent study,we evaluated glycemic parameters and PROs over one year of continuous use of Medtronic’s 670G HCL in real-world clinical practice.AIM To assess the effects of hybrid closed loop system on glycemic control and quality of life in adults with T1D.METHODS We evaluated 71 patients with T1D(mean age:45.5±12.1 years;59%females;body weight:83.8±18.7 kg,body mass index:28.7±5.6 kg/m2,A1C:7.6%±0.8%)who were treated with HCL at Joslin Clinic from 2017 to 2019.We measured A1C and percent of glucose time-in-range(%TIR)at baseline and 12 months.We measured percent time in auto mode(%TiAM)for the last two weeks preceding the final visit and assessed PROs through several validated quality-of-life surveys related to general health and diabetes management.RESULTS At 12 mo,A1C decreased by 0.3%±0.1%(P=0.001)and%TIR increased by 8.1%±2.5%(P=0.002).The average%TiAM was only 64.3%±32.8%and was not associated with A1C,%TIR or PROs.PROs,provided at baseline and at the end of the study,showed that the physical functioning submodule of 36Item Short-Form Health Survey increased significantly by 22.9%(P<0.001).Hypoglycemia fear survey/worry scale decreased significantly by 24.9%(P<0.000);Problem Areas In Diabetes reduced significantly by-17.2%(P=0.002).The emotional burden submodules of dietary diversity score reduced significantly by-44.7%(P=0.001).Furthermore,analysis of Clarke questionnaire showed no increase in awareness of hypoglycemic episodes.WHO-5 showed no improvements in subject’s wellbeing among participants after starting the 670G HCL system.Finally,analysis of Pittsburgh Sleep Quality Index showed no difference in sleep quality,sleep latency,or duration of sleep from baseline to 12 mo.CONCLUSION The use of HCL in real-world clinical practice for one year was associated with significant improvements in A1C,%TIR,physical functioning,hypoglycemia fear,emotional distress,and emotional burden related to diabetes management.However,these changes were not associated with time in auto mode. 展开更多
关键词 Artificial pancreas Continuous blood glucose monitor Type 1 diabetes Hybrid closed-loop insulin delivery Quality of life
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Indications of pro-inflammatory cytokines in laparoscopic and open liver resection for early-stage hepatocellular carcinoma
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作者 Kevin Tak-Pan Ng Li Pang +5 位作者 Jia-Qi Wang Wong Hoi She Simon Hing-Yin Tsang Chung Mau Lo Kwan Man Tan To Cheung 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2024年第3期257-264,共8页
Background:Our clinical practice of laparoscopic liver resection(LLR)had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma(HCC)over open liver resection(OLR),but the underlyi... Background:Our clinical practice of laparoscopic liver resection(LLR)had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma(HCC)over open liver resection(OLR),but the underlying mechanisms are not clear.This study was to find out whether systemic inflammation plays an important role.Methods:A total of 103 patients with early-stage HCC under liver resection were enrolled(LLR group,n=53;OLR group,n=50).The expression of 9 inflammatory cytokines in patients at preoperation,postoperative day 1(POD1)and POD7 was quantified by Luminex Multiplex assay.The relationships of the cytokines and the postoperative outcomes were compared between LLR and OLR.Results:Seven of the circulating cytokines were found to be significantly upregulated on POD1 after LLR or OLR compared to their preoperative levels.Compared to OLR,the POD1 levels of granulocytemacrophage colony-stimulating factor(GM-CSF),interleukin-6(IL-6),IL-8,and monocyte chemoattractant protein-1(MCP-1)in the LLR group were significantly lower.Higher POD1 levels of these cytokines were significantly correlated with longer operative time and higher volume of blood loss during operation.The levels of these cytokines were positively associated with postoperative liver injury,and the length of hospital stay.Importantly,a high level of IL-6 at POD1 was a risk factor for HCC recurrence and poor disease-free survival after liver resection.Conclusions:Significantly lower level of GM-CSF,IL-6,IL-8,and MCP-1 after liver resection represented a milder systemic inflammation which might be an important mechanism to offer better short-term and long-term outcomes in LLR over OLR. 展开更多
关键词 Laparoscopic liver resection open liver resection Hepatocellular carcinoma Postoperative cytokines Inflammatory responses
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Effect of Jianpi Shengxue Tablet on Iron Metabolism and Nutritional Status in Patients with Renal Anemia:A Prospective,Randomized,Open,Parallel Controlled and Multicenter Clinical Study
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作者 Juan YANG Meng-yuan LIANG +15 位作者 Yu LI Hao ZHANG Wei LI Jing LV Li-ping DONG Jing-song JIN Cheng YANG Qing-hong ZHANG Li LONG Rong ZOU Yi GAO Dan SONG Chun-qin PAN Ying YAO Xiao-lin ZHAN Xiao-hui WANG 《Current Medical Science》 SCIE CAS 2024年第3期603-610,共8页
Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled a... Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled and randomly divided into two groups.Patients in the control group were treated with polysaccharide-iron complex,and those in the experimental group were administered Jianpi Shengxue tablet.After 8 weeks of continuous treatment,the therapeutic outcomes regarding anemia were compared between the two groups.Results After treatment,the red blood cell(RBC)count,hematocrit(HCT),reticulocyte percentage(RET),ferritin(SF),serum iron(SI),transferrin saturation(TSAT),and serum albumin(ALB)all increased(P<0.01),and the clinical symptom score and total iron binding capacity decreased(P<0.01)in the experimental group.Moreover,the improvements in RBC,HCT,RET,SF,SI,TAST,ALB,and clinical symptoms(fatigue,anorexia,dull skin complexion,numbness of hands and feet)in the experimental group were significantly greater than those in the control group(P<0.05).The total effective rate for treating renal anemia was significantly higher in the experimental group than in the control group(P<0.01).Conclusion The Jianpi Shengxue tablet demonstrates efficacy in treating renal anemia,leading to significant improvements in the laboratory examination results and clinical symptoms of patients with renal anemia. 展开更多
关键词 Jianpi Shengxue tablet renal anemia RANDOMIZED open parallel control multicenter clinical study
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RB-DEM Modeling and Simulation of Non-Persisting Rough Open Joints Based on the IFS-Enhanced Method
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作者 Hangtian Song Xudong Chen +3 位作者 Chun Zhu Qian Yin Wei Wang Qingxiang Meng 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期337-359,共23页
When the geological environment of rock masses is disturbed,numerous non-persisting open joints can appear within it.It is crucial to investigate the effect of open joints on the mechanical properties of rock mass.How... When the geological environment of rock masses is disturbed,numerous non-persisting open joints can appear within it.It is crucial to investigate the effect of open joints on the mechanical properties of rock mass.However,it has been challenging to generate realistic open joints in traditional experimental tests and numerical simulations.This paper presents a novel solution to solve the problem.By utilizing the stochastic distribution of joints and an enhanced-fractal interpolation system(IFS)method,rough curves with any orientation can be generated.The Douglas-Peucker algorithm is then applied to simplify these curves by removing unnecessary points while preserving their fundamental shape.Subsequently,open joints are created by connecting points that move to both sides of rough curves based on the aperture distribution.Mesh modeling is performed to construct the final mesh model.Finally,the RB-DEM method is applied to transform the mesh model into a discrete element model containing geometric information about these open joints.Furthermore,this study explores the impacts of rough open joint orientation,aperture,and number on rock fracture mechanics.This method provides a realistic and effective approach for modeling and simulating these non-persisting open joints. 展开更多
关键词 Non-persisting rough open joints stochastic distribution of joints enhanced-IFS method RB-DEM
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BSEC Method for Unveiling Open Clusters and its Application to Gaia DR3:83 New Clusters
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作者 Zhong-Mu Li Cai-Yan Mao 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2024年第5期169-184,共16页
Open clusters(OCs) are common in the Milky Way, but most of them remain undiscovered. There are numerous techniques, including some machine-learning algorithms, available for the exploration of OCs. However, each meth... Open clusters(OCs) are common in the Milky Way, but most of them remain undiscovered. There are numerous techniques, including some machine-learning algorithms, available for the exploration of OCs. However, each method has its limitations and therefore, different approaches to discovering OCs hold significant values. We develop a comprehensive approach method to automatically explore the data space and identify potential OC candidates with relatively reliable membership determination. This approach combines the techniques of Hierarchical Density-Based Spatial Clustering of Applications with Noise, Gaussian mixture model, and a novel cluster member identification technique, color excess constraint. The new method exhibits efficiency in detecting OCs while ensuring precise determination of cluster memberships. Because the main feature of this technique is to add an extra constraint(EC) for the members of cluster candidates using the homogeneity of color excess,compared to typical blind search codes, it is called Blind Search-Extra Constraint(BSEC) method. It is successfully applied to the Gaia Data Release 3, and 83 new OCs are found, whose color–magnitude diagrams(CMDs) are fitted well to the isochrones. In addition, this study reports 621 new OC candidates with discernible main sequence or red giant branch. It is shown that BSEC technique can discard some false negatives of previous works, which takes about three percentage of known clusters. It shows that as an EC, the color excess(or twocolor) constraint is useful for removing fake cluster member stars from the clusters that are identified from the positions and proper motions of stars, and getting more precise CMDs, when differential reddening of member stars of a cluster is not large(e.g., ΔE(G_(BP)-G_(RP)) < 0.5 mag). It makes the CMDs of 15% clusters clearer(in particular for the region near turnoff) and therefore is helpful for CMD and stellar population studies. Our result suggests that the color excess constraint is more appropriate for clusters with small differential reddening, such as globular clusters or older OCs, and clusters that the distances of member stars cannot be determined accurately. 展开更多
关键词 GALAXY stellar content-(Galaxy:)open clusters and associations general-stars fundamental parameters
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