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Oxidative Stress before and after Operation in Patients with Chronic Cholecystitis Containing Gallstone 被引量:10
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作者 ZHOU JUN FU , CHEN PENG , YANG JIN LU +, ZHU YOU GEN + PENG CHENG HONG , AND WU YU LIAN The 2nd Affiliated Hospital, Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejian 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2000年第4期254-262,共9页
To study the relationship of oxidative, antioxidative constituents and antioxidases in blood with chronic cholecystitis containing gallstone, levels of lipoperoxides (LPO), nitric oxide (NO), vitamin C(VC), vitamin E ... To study the relationship of oxidative, antioxidative constituents and antioxidases in blood with chronic cholecystitis containing gallstone, levels of lipoperoxides (LPO), nitric oxide (NO), vitamin C(VC), vitamin E (VE) and β carotene (β CAR) in plasma as well as level of LPO, activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH Px) in erythrocytes were investigated by spectrophotometric assay in 107 patients with this condition (PCg) and 100 healthy volunteers (HVs). Compared with HVs group, the average value of LPO and NO in plasma and that of LPO in erythrocytes of PCg group were significantly increased ( P <0.0001), while that of VC, VE and β CAR in plasma and the average activities of SOD, CAT and GSH Px in erythrocytes were significantly decreased ( P <0.0001). Linear regression and correlation analysis for 107 preoperative PCg showed that the value of LPO and NO in plasma and that of LPO in erythrocytes of PCg gradually increased ( P <0.0001), representing a significant linear positive correlation. The value of VC, VE and β CAR in plasma and that of SOD, CAT and GSH Px in erythrocytes of PCg gradually decreased ( P <0.0001), representing a significant linear negative correlation. Stepwise regression and correlation analysis for 107 preoperative PCg suggested that the closest correlation was observed between the course of disease and the value of NO and VC in plasma and that of SOD, GSH Px and LPO in erythrocytes, r =0.7306, F =32.1408, P <0.0001. Compared with the preoperative PCg group, the average value of LPO and NO in plasma and that of LPO in erythrocytes of the postoperative PCg group were significantly decreased ( P <0.0001). Furthermore, the average value of VC in plasma and that of SOD, CAT and GSH Px in erythrocytes of the postoperative PCg group were significantly increased ( P <0.0001), whereas no significant difference was found between their average value of VE and β CAR in plasma. These findings suggested that oxidative stress was an aggravating pathological condition in PCg group. Therefore, we recommend that in treating PCg, antioxidants such as VC, VE, β CAR should be given in order to alleviate their potential oxidative damages. 展开更多
关键词 Wang with Chronic Cholecystitis Containing Gallstone Oxidative Stress before and after operation in patients
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Investigation on the infectant target testing of the patient blood before transfusion and operation
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《中国输血杂志》 CAS CSCD 2001年第S1期344-,共1页
关键词 Investigation on the infectant target testing of the patient blood before transfusion and operation
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Should Doctors Be Allowed to Impose Operations on Patients?
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《Beijing Review》 2007年第52期46-47,共2页
Li Liyun,a 22-year-old who was in her ninth month of pregnancy,died of serious pneumonia at Chaoyang Hospital in west Beijing on November 21,after her husband refused to let doctors perform a Caesarean sec- tion.The h... Li Liyun,a 22-year-old who was in her ninth month of pregnancy,died of serious pneumonia at Chaoyang Hospital in west Beijing on November 21,after her husband refused to let doctors perform a Caesarean sec- tion.The hospital had offered to do the operation free of charge but the husband did not believe it. 展开更多
关键词 Should Doctors Be Allowed to Impose operations on patients BE
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