An analytical validation for the attenuation of lateral propagating light in sea ice

The attenuation of lateral propagating light （LPL） in sea ice was measured using an artificial light source in the Canadian Arctic during the 2007/2008 winter. The apparent attenuation coefficientμ（λ）for lateral prop-agating light was obtained from the measured logarithmic relative variation rate. In this study an analytical solution based on the strict optical theories is developed to validate the measured result. There is a good consistency between theoretical solution and measured data, by which a quite simple but very rigorous relationship among the light source, measurement geometry, and measured irradiance is established. The attenuation coefficients acquired by measurement and theory are the diffusion attenuation as an apparent optical property of ice, independent of the light source and shining condition. The attenuation ability of sea ice should be caused by the microstructure of sea ice, such as crystal size, ice density, brine volume, air inclusion, etc. It also includes the leak from both interfaces by directional scattering. It is verified that the measuring approach is operational and accurate to measure the attenuation of the LPL. The solution from this study did not tell the connection among the extinction and the inclusions of sea ice theoretically be-cause of insufficient understanding.

Monitoring of edema progression in permanent and transient MCAO model using SS-OCT

Cerebral edema is a severe complication of acute ischemic stroke with high mortality but limited treatment.Although parameters such as brain water content and intracranial pressure may represent the global assessment of edema,optical properties can appear heterogeneously throughout the cerebral tissue relative to the site of injury.In this study,we have monitored the edema formation and progression in both permanent and transient middle cerebral artery oc-clusion models in rats.Edema was reflected by the decrease of optical attenuation coefficient(OAC)value in OCT system.By utilizing swept-source optical coherence tomography(SS-OCT),we found that in photochemically induced permanent focal stroke model,both the edema size and edema index,steadily developed until the end of monitor(7 h).Comparatively,when transient ischemia was introduced with endothelin-1(ET-1),the edema was detected as early as 15 min,and began to recover after 30 min until monitor was finished(3 h).Despite the majority of the edema being recovered to some extent,the condition of a small region within the edema kept deteriorating,presumably due to the reperfusion damage which might result in serious clinical outcomes.Our study has compared the edema characteristics from two different acute ischemic stroke situations.This work not only confirms the capability of OCT to temporal and spatial monitor of edema but is also able to locate focal conditions at some areas that might highly determine the prognosis and treatment decisions.