This work is concerned with a kind of optimal control problem for a size-structured biological population model.Well-posedness of the state system and an adjoint system are proved by means of Banach's fixed point the...This work is concerned with a kind of optimal control problem for a size-structured biological population model.Well-posedness of the state system and an adjoint system are proved by means of Banach's fixed point theorem.Existence and uniqueness of optimal control are shown by functional analytical approach.Optimality conditions describing the optimal strategy are established via tangent and normal cones technique.The results are of the first ones for this novel structure.展开更多
Background Asian population are at increased risk of bleeding during the warfarin treatment,so the recommended optimal international normalized ratio(INR)level may be lower in Asians than in Westerners.The aim of this...Background Asian population are at increased risk of bleeding during the warfarin treatment,so the recommended optimal international normalized ratio(INR)level may be lower in Asians than in Westerners.The aim of this prospective multicenter study was to determine the optimal INR level in Thai patients with non-valvular atrial fibrillation(NVAF).Methods Patients with NVAF who were on warfarin for stroke prevention were recruited from 27 hospitals in the nationwide COOL-AF registry in Thailand.We collected demographic data,medical history,risk factors for stroke and bleeding,concomitant disease,electrocardiogram and laboratory data including INR and antithrombotic medications.Outcome measurements included ischemic stroke/transient ischemic attack(TIA)and major bleeding.Optimal INR level was assessed by the calculation of incidence density for six INR ranges(<1.5,1.5–1.99,2–2.49,2.5–2.99,3–3.49,and≥3.5).Results A total of 2,232 patients were included.The mean age of patients was 68.5±10.6 years.The mean follow-up duration was 25.7±10.6 months.There were 63 ischemic stroke/TIA and 112 major bleeding events.The lowest prevalence of ischemic stroke/TIA and major bleeding events occurred within the INR range of 2.0–2.99 for patients<70 years and 1.5–2.99 for patients≥70 years.Conclusions The INR range associated with the lowest risk of ischemic stroke/TIA and bleeding in the Thai population was 2.0–2.99 for patients<70 years and 1.5–2.99 for patients≥70 years.The rates of major bleeding and ischemic stroke/TIA were both higher than the rates reported in Western population.展开更多
Owing to technological developments,Medical image analysis has received considerable attention in the rapid detection and classification of diseases.The brain is an essential organ in humans.Brain tumors cause loss of...Owing to technological developments,Medical image analysis has received considerable attention in the rapid detection and classification of diseases.The brain is an essential organ in humans.Brain tumors cause loss of memory,vision,and name.In 2020,approximately 18,020 deaths occurred due to brain tumors.These cases can be minimized if a brain tumor is diagnosed at a very early stage.Computer vision researchers have introduced several techniques for brain tumor detection and classification.However,owing to many factors,this is still a challenging task.These challenges relate to the tumor size,the shape of a tumor,location of the tumor,selection of important features,among others.In this study,we proposed a framework for multimodal brain tumor classification using an ensemble of optimal deep learning features.In the proposed framework,initially,a database is normalized in the form of high-grade glioma(HGG)and low-grade glioma(LGG)patients and then two pre-trained deep learning models(ResNet50 and Densenet201)are chosen.The deep learning models were modified and trained using transfer learning.Subsequently,the enhanced ant colony optimization algorithm is proposed for best feature selection from both deep models.The selected features are fused using a serial-based approach and classified using a cubic support vector machine.The experimental process was conducted on the BraTs2019 dataset and achieved accuracies of 87.8%and 84.6%for HGG and LGG,respectively.The comparison is performed using several classification methods,and it shows the significance of our proposed technique.展开更多
In the reliability designing procedure of the vehicle components, when the distribution styles of the random variables are unknown or non-normal distribution, the result evaluated contains great error or even is wrong...In the reliability designing procedure of the vehicle components, when the distribution styles of the random variables are unknown or non-normal distribution, the result evaluated contains great error or even is wrong if the reliability value R is larger than 1 by using the existent method, in which case the formula is necessary to be revised. This is obviously inconvenient for programming. Combining reliability-based optimization theory, robust designing method and reliability based sensitivity analysis, a new method for reliability robust designing is proposed. Therefore the influence level of the designing parameters’ changing to the reliability of vehicle components can be obtained. The reliability sensitivity with respect to design parameters is viewed as a sub-objective function in the multi-objective optimization problem satisfying reliability constraints. Given the first four moments of basic random variables, a fourth-moment technique and the proposed optimization procedure can obtain reliability-based robust design of automobile components with non-normal distribution parameters accurately and quickly. By using the proposed method, the distribution style of the random parameters is relaxed. Therefore it is much closer to the actual reliability problems. The numerical examples indicate the following: (1) The reliability value obtained by the robust method proposed increases (】0.04%) comparing to the value obtained by the ordinary optimization algorithm; (2) The absolute value of reliability-based sensitivity decreases (】0.01%), and the robustness of the products’ quality is improved accordingly. Utilizing the reliability-based optimization and robust design method in the reliability designing procedure reduces the manufacture cost and provides the theoretical basis for the reliability and robust design of the vehicle components.展开更多
By means of analysing the mechanism of blending materials,a general blending efficiency model was proposed.Applying this general model to an example 9 a suitable formula of blending efficiency which is more accurate t...By means of analysing the mechanism of blending materials,a general blending efficiency model was proposed.Applying this general model to an example 9 a suitable formula of blending efficiency which is more accurate than those in papers[2-3]was obtained.Finally,a high-precision optimal combining prediction formula for calculating blending efficiency was proposed.展开更多
Recently medical image classification plays a vital role in medical image retrieval and computer-aided diagnosis system.Despite deep learning has proved to be superior to previous approaches that depend on handcrafted...Recently medical image classification plays a vital role in medical image retrieval and computer-aided diagnosis system.Despite deep learning has proved to be superior to previous approaches that depend on handcrafted features;it remains difficult to implement because of the high intra-class variance and inter-class similarity generated by the wide range of imaging modalities and clinical diseases.The Internet of Things(IoT)in healthcare systems is quickly becoming a viable alternative for delivering high-quality medical treatment in today’s e-healthcare systems.In recent years,the Internet of Things(IoT)has been identified as one of the most interesting research subjects in the field of health care,notably in the field of medical image processing.For medical picture analysis,researchers used a combination of machine and deep learning techniques as well as artificial intelligence.These newly discovered approaches are employed to determine diseases,which may aid medical specialists in disease diagnosis at an earlier stage,giving precise,reliable,efficient,and timely results,and lowering death rates.Based on this insight,a novel optimal IoT-based improved deep learning model named optimization-driven deep belief neural network(ODBNN)is proposed in this article.In context,primarily image quality enhancement procedures like noise removal and contrast normalization are employed.Then the preprocessed image is subjected to feature extraction techniques in which intensity histogram,an average pixel of RGB channels,first-order statistics,Grey Level Co-Occurrence Matrix,Discrete Wavelet Transform,and Local Binary Pattern measures are extracted.After extracting these sets of features,the May Fly optimization technique is adopted to select the most relevant features.The selected features are fed into the proposed classification algorithm in terms of classifying similar input images into similar classes.The proposed model is evaluated in terms of accuracy,precision,recall,and f-measure.The investigation evident the performance of incorporating optimization techniques for medical image classification is better than conventional techniques.展开更多
About 170 nations have been affected by the COvid VIrus Disease-19(COVID-19)epidemic.On governing bodies across the globe,a lot of stress is created by COVID-19 as there is a continuous rise in patient count testing p...About 170 nations have been affected by the COvid VIrus Disease-19(COVID-19)epidemic.On governing bodies across the globe,a lot of stress is created by COVID-19 as there is a continuous rise in patient count testing positive,and they feel challenging to tackle this situation.Most researchers concentrate on COVID-19 data analysis using the machine learning paradigm in these situations.In the previous works,Long Short-Term Memory(LSTM)was used to predict future COVID-19 cases.According to LSTM network data,the outbreak is expected tofinish by June 2020.However,there is a chance of an over-fitting problem in LSTM and true positive;it may not produce the required results.The COVID-19 dataset has lower accuracy and a higher error rate in the existing system.The proposed method has been introduced to overcome the above-mentioned issues.For COVID-19 prediction,a Linear Decreasing Inertia Weight-based Cat Swarm Optimization with Half Binomial Distribution based Convolutional Neural Network(LDIWCSO-HBDCNN)approach is presented.In this suggested research study,the COVID-19 predicting dataset is employed as an input,and the min-max normalization approach is employed to normalize it.Optimum features are selected using Linear Decreasing Inertia Weight-based Cat Swarm Optimization(LDIWCSO)algorithm,enhancing the accuracy of classification.The Cat Swarm Optimization(CSO)algorithm’s convergence is enhanced using inertia weight in the LDIWCSO algorithm.It is used to select the essential features using the bestfitness function values.For a specified time across India,death and confirmed cases are predicted using the Half Binomial Distribution based Convolutional Neural Network(HBDCNN)technique based on selected features.As demonstrated by empirical observations,the proposed system produces significant performance in terms of f-measure,recall,precision,and accuracy.展开更多
冷热电联产(combined cooling, heating and power,CCHP)系统与微电网的结合有利于促进消纳可再生能源,为了提升CCHP型微电网的经济性、环保性和稳定性,提出了两阶段优化调度模型。离线优化阶段基于需求侧响应策略,建立了基于归一化法...冷热电联产(combined cooling, heating and power,CCHP)系统与微电网的结合有利于促进消纳可再生能源,为了提升CCHP型微电网的经济性、环保性和稳定性,提出了两阶段优化调度模型。离线优化阶段基于需求侧响应策略,建立了基于归一化法向约束法的多目标规划模型,并用熵权-TOPSIS法筛选最优结果。在线优化阶段建立了基于动态矩阵控制算法的有限时域优化模型,对离线优化结果进行跟踪优化和反馈校正,以降低不确定性因素的影响。最后,设计对比方案进行分析,验证了所提优化模型的有效性。展开更多
街道景观空间对市民健康和城市风貌具有重要影响。既往研究中常以归一化植被指数(NDVI)和绿视率(GVI)来分别代表二维和三维的绿色指标,但对二者的指标相关性研究甚少。采用基于深度学习的图像语义分割方法分析百度街景计算代表性街道的G...街道景观空间对市民健康和城市风貌具有重要影响。既往研究中常以归一化植被指数(NDVI)和绿视率(GVI)来分别代表二维和三维的绿色指标,但对二者的指标相关性研究甚少。采用基于深度学习的图像语义分割方法分析百度街景计算代表性街道的GVI,利用GF-1卫星数据计算NDVI,比较分析城市街道的GVI和NDVI指标特征及相关性。结果表明,1)中山市中心城区各代表街道GVI指标参差不齐,从8.06%到36.00%,其中石岐街道兴中道GVI最高;2)各街道观测点的NDVI均值随着缓冲区尺度的增加也随之呈现出不同变化,NDVI均值具有强烈的尺度敏感性;3)50 m GVI和DNVI均值的皮尔逊相关系数最高,达到0.832。在此基础上分析街道景观存在的不足并给出优化建议,为城市街景评估、空间优化、景观提升提供参考。展开更多
基金Supported by the ZPNSFC (LY12A01023)the National Natural Science Foundation of China (11271104,11061017)
文摘This work is concerned with a kind of optimal control problem for a size-structured biological population model.Well-posedness of the state system and an adjoint system are proved by means of Banach's fixed point theorem.Existence and uniqueness of optimal control are shown by functional analytical approach.Optimality conditions describing the optimal strategy are established via tangent and normal cones technique.The results are of the first ones for this novel structure.
基金the Health System Research Institute(59-053)the Heart Association of Thailand under the Royal Patronage of H.M.the King.All authors had no conflicts of interest to disclose.The authors gratefully acknowledge Pontawee Kaewcomdee and Olaree Chaiphet for data management,and all investigators and nurse coordinators of the COOL-AF registry.
文摘Background Asian population are at increased risk of bleeding during the warfarin treatment,so the recommended optimal international normalized ratio(INR)level may be lower in Asians than in Westerners.The aim of this prospective multicenter study was to determine the optimal INR level in Thai patients with non-valvular atrial fibrillation(NVAF).Methods Patients with NVAF who were on warfarin for stroke prevention were recruited from 27 hospitals in the nationwide COOL-AF registry in Thailand.We collected demographic data,medical history,risk factors for stroke and bleeding,concomitant disease,electrocardiogram and laboratory data including INR and antithrombotic medications.Outcome measurements included ischemic stroke/transient ischemic attack(TIA)and major bleeding.Optimal INR level was assessed by the calculation of incidence density for six INR ranges(<1.5,1.5–1.99,2–2.49,2.5–2.99,3–3.49,and≥3.5).Results A total of 2,232 patients were included.The mean age of patients was 68.5±10.6 years.The mean follow-up duration was 25.7±10.6 months.There were 63 ischemic stroke/TIA and 112 major bleeding events.The lowest prevalence of ischemic stroke/TIA and major bleeding events occurred within the INR range of 2.0–2.99 for patients<70 years and 1.5–2.99 for patients≥70 years.Conclusions The INR range associated with the lowest risk of ischemic stroke/TIA and bleeding in the Thai population was 2.0–2.99 for patients<70 years and 1.5–2.99 for patients≥70 years.The rates of major bleeding and ischemic stroke/TIA were both higher than the rates reported in Western population.
基金This study was supported by the grants of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare(HI18C1216)the grant of the National Research Foundation of Korea(NRF-2020R1I1A1A01074256)the Soonchunhyang University Research Fund.
文摘Owing to technological developments,Medical image analysis has received considerable attention in the rapid detection and classification of diseases.The brain is an essential organ in humans.Brain tumors cause loss of memory,vision,and name.In 2020,approximately 18,020 deaths occurred due to brain tumors.These cases can be minimized if a brain tumor is diagnosed at a very early stage.Computer vision researchers have introduced several techniques for brain tumor detection and classification.However,owing to many factors,this is still a challenging task.These challenges relate to the tumor size,the shape of a tumor,location of the tumor,selection of important features,among others.In this study,we proposed a framework for multimodal brain tumor classification using an ensemble of optimal deep learning features.In the proposed framework,initially,a database is normalized in the form of high-grade glioma(HGG)and low-grade glioma(LGG)patients and then two pre-trained deep learning models(ResNet50 and Densenet201)are chosen.The deep learning models were modified and trained using transfer learning.Subsequently,the enhanced ant colony optimization algorithm is proposed for best feature selection from both deep models.The selected features are fused using a serial-based approach and classified using a cubic support vector machine.The experimental process was conducted on the BraTs2019 dataset and achieved accuracies of 87.8%and 84.6%for HGG and LGG,respectively.The comparison is performed using several classification methods,and it shows the significance of our proposed technique.
基金supported by National Natural Science Foundation of China (Grant Nos. 51135003, U1234208, 51205050)New Teachers' Fund for Doctor Stations of Ministry of Education of China (Grant No.20110042120020)+1 种基金Fundamental Research Funds for the Central Universities, China (Grant No. N110303003)China Postdoctoral Science Foundation (Grant No. 2011M500564)
文摘In the reliability designing procedure of the vehicle components, when the distribution styles of the random variables are unknown or non-normal distribution, the result evaluated contains great error or even is wrong if the reliability value R is larger than 1 by using the existent method, in which case the formula is necessary to be revised. This is obviously inconvenient for programming. Combining reliability-based optimization theory, robust designing method and reliability based sensitivity analysis, a new method for reliability robust designing is proposed. Therefore the influence level of the designing parameters’ changing to the reliability of vehicle components can be obtained. The reliability sensitivity with respect to design parameters is viewed as a sub-objective function in the multi-objective optimization problem satisfying reliability constraints. Given the first four moments of basic random variables, a fourth-moment technique and the proposed optimization procedure can obtain reliability-based robust design of automobile components with non-normal distribution parameters accurately and quickly. By using the proposed method, the distribution style of the random parameters is relaxed. Therefore it is much closer to the actual reliability problems. The numerical examples indicate the following: (1) The reliability value obtained by the robust method proposed increases (】0.04%) comparing to the value obtained by the ordinary optimization algorithm; (2) The absolute value of reliability-based sensitivity decreases (】0.01%), and the robustness of the products’ quality is improved accordingly. Utilizing the reliability-based optimization and robust design method in the reliability designing procedure reduces the manufacture cost and provides the theoretical basis for the reliability and robust design of the vehicle components.
文摘By means of analysing the mechanism of blending materials,a general blending efficiency model was proposed.Applying this general model to an example 9 a suitable formula of blending efficiency which is more accurate than those in papers[2-3]was obtained.Finally,a high-precision optimal combining prediction formula for calculating blending efficiency was proposed.
基金This research is financially supported by the Deanship of Scientific Research at King Khalid University under research grant number(RGP.2/202/43).
文摘Recently medical image classification plays a vital role in medical image retrieval and computer-aided diagnosis system.Despite deep learning has proved to be superior to previous approaches that depend on handcrafted features;it remains difficult to implement because of the high intra-class variance and inter-class similarity generated by the wide range of imaging modalities and clinical diseases.The Internet of Things(IoT)in healthcare systems is quickly becoming a viable alternative for delivering high-quality medical treatment in today’s e-healthcare systems.In recent years,the Internet of Things(IoT)has been identified as one of the most interesting research subjects in the field of health care,notably in the field of medical image processing.For medical picture analysis,researchers used a combination of machine and deep learning techniques as well as artificial intelligence.These newly discovered approaches are employed to determine diseases,which may aid medical specialists in disease diagnosis at an earlier stage,giving precise,reliable,efficient,and timely results,and lowering death rates.Based on this insight,a novel optimal IoT-based improved deep learning model named optimization-driven deep belief neural network(ODBNN)is proposed in this article.In context,primarily image quality enhancement procedures like noise removal and contrast normalization are employed.Then the preprocessed image is subjected to feature extraction techniques in which intensity histogram,an average pixel of RGB channels,first-order statistics,Grey Level Co-Occurrence Matrix,Discrete Wavelet Transform,and Local Binary Pattern measures are extracted.After extracting these sets of features,the May Fly optimization technique is adopted to select the most relevant features.The selected features are fed into the proposed classification algorithm in terms of classifying similar input images into similar classes.The proposed model is evaluated in terms of accuracy,precision,recall,and f-measure.The investigation evident the performance of incorporating optimization techniques for medical image classification is better than conventional techniques.
文摘About 170 nations have been affected by the COvid VIrus Disease-19(COVID-19)epidemic.On governing bodies across the globe,a lot of stress is created by COVID-19 as there is a continuous rise in patient count testing positive,and they feel challenging to tackle this situation.Most researchers concentrate on COVID-19 data analysis using the machine learning paradigm in these situations.In the previous works,Long Short-Term Memory(LSTM)was used to predict future COVID-19 cases.According to LSTM network data,the outbreak is expected tofinish by June 2020.However,there is a chance of an over-fitting problem in LSTM and true positive;it may not produce the required results.The COVID-19 dataset has lower accuracy and a higher error rate in the existing system.The proposed method has been introduced to overcome the above-mentioned issues.For COVID-19 prediction,a Linear Decreasing Inertia Weight-based Cat Swarm Optimization with Half Binomial Distribution based Convolutional Neural Network(LDIWCSO-HBDCNN)approach is presented.In this suggested research study,the COVID-19 predicting dataset is employed as an input,and the min-max normalization approach is employed to normalize it.Optimum features are selected using Linear Decreasing Inertia Weight-based Cat Swarm Optimization(LDIWCSO)algorithm,enhancing the accuracy of classification.The Cat Swarm Optimization(CSO)algorithm’s convergence is enhanced using inertia weight in the LDIWCSO algorithm.It is used to select the essential features using the bestfitness function values.For a specified time across India,death and confirmed cases are predicted using the Half Binomial Distribution based Convolutional Neural Network(HBDCNN)technique based on selected features.As demonstrated by empirical observations,the proposed system produces significant performance in terms of f-measure,recall,precision,and accuracy.
文摘冷热电联产(combined cooling, heating and power,CCHP)系统与微电网的结合有利于促进消纳可再生能源,为了提升CCHP型微电网的经济性、环保性和稳定性,提出了两阶段优化调度模型。离线优化阶段基于需求侧响应策略,建立了基于归一化法向约束法的多目标规划模型,并用熵权-TOPSIS法筛选最优结果。在线优化阶段建立了基于动态矩阵控制算法的有限时域优化模型,对离线优化结果进行跟踪优化和反馈校正,以降低不确定性因素的影响。最后,设计对比方案进行分析,验证了所提优化模型的有效性。
文摘街道景观空间对市民健康和城市风貌具有重要影响。既往研究中常以归一化植被指数(NDVI)和绿视率(GVI)来分别代表二维和三维的绿色指标,但对二者的指标相关性研究甚少。采用基于深度学习的图像语义分割方法分析百度街景计算代表性街道的GVI,利用GF-1卫星数据计算NDVI,比较分析城市街道的GVI和NDVI指标特征及相关性。结果表明,1)中山市中心城区各代表街道GVI指标参差不齐,从8.06%到36.00%,其中石岐街道兴中道GVI最高;2)各街道观测点的NDVI均值随着缓冲区尺度的增加也随之呈现出不同变化,NDVI均值具有强烈的尺度敏感性;3)50 m GVI和DNVI均值的皮尔逊相关系数最高,达到0.832。在此基础上分析街道景观存在的不足并给出优化建议,为城市街景评估、空间优化、景观提升提供参考。