Reversible data hiding is an information hiding technique that requires the retrieval of the error free cover image after the extraction of the secret image.We suggested a technique in this research that uses a recurs...Reversible data hiding is an information hiding technique that requires the retrieval of the error free cover image after the extraction of the secret image.We suggested a technique in this research that uses a recursive embedding method to increase capacity substantially using the Integer wavelet transform and the Arnold transform.The notion of Integer wavelet transforms is to ensure that all coefficients of the cover images are used during embedding with an increase in payload.By scrambling the cover image,Arnold transform adds security to the information that gets embedded and also allows embedding more information in each iteration.The hybrid combination of Integer wavelet transform and Arnold transform results to build a more efficient and secure system.The proposed method employs a set of keys to ensure that information cannot be decoded by an attacker.The experimental results show that it aids in the development of a more secure storage system and withstand few tampering attacks The suggested technique is tested on many image formats,including medical images.Various performance metrics proves that the retrieved cover image and hidden image are both intact.This System is proven to withstand rotation attack as well.展开更多
传统抗体偶联药物(antibody drug conjugates,ADC)通过将单克隆抗体与细胞毒性药物相结合,实现对癌细胞的精准打击,但在稳定性、靶向性、疗效及安全性等方面依然存在诸多不足。新型ADC,如双特异性、位点特异性、双有效载荷和前药型ADC,...传统抗体偶联药物(antibody drug conjugates,ADC)通过将单克隆抗体与细胞毒性药物相结合,实现对癌细胞的精准打击,但在稳定性、靶向性、疗效及安全性等方面依然存在诸多不足。新型ADC,如双特异性、位点特异性、双有效载荷和前药型ADC,通过同时结合2个不同抗原或表位、选择更稳定的连接子、与抗体特定氨基酸位点偶联、携带不同药物有效载荷以及采用前药策略等优化方法,在保留传统ADC作用特点的基础上,显著提高药物的稳定性、靶向性、疗效和安全性,能更好地满足临床治疗的需求。新型ADC可能会在未来的癌症治疗中发挥重要的作用。探讨新型ADC在癌症治疗中的进展并分析其优势与挑战,可为开发抗癌策略提供理论支持,为药物研发提供方向。展开更多
文摘Reversible data hiding is an information hiding technique that requires the retrieval of the error free cover image after the extraction of the secret image.We suggested a technique in this research that uses a recursive embedding method to increase capacity substantially using the Integer wavelet transform and the Arnold transform.The notion of Integer wavelet transforms is to ensure that all coefficients of the cover images are used during embedding with an increase in payload.By scrambling the cover image,Arnold transform adds security to the information that gets embedded and also allows embedding more information in each iteration.The hybrid combination of Integer wavelet transform and Arnold transform results to build a more efficient and secure system.The proposed method employs a set of keys to ensure that information cannot be decoded by an attacker.The experimental results show that it aids in the development of a more secure storage system and withstand few tampering attacks The suggested technique is tested on many image formats,including medical images.Various performance metrics proves that the retrieved cover image and hidden image are both intact.This System is proven to withstand rotation attack as well.
文摘传统抗体偶联药物(antibody drug conjugates,ADC)通过将单克隆抗体与细胞毒性药物相结合,实现对癌细胞的精准打击,但在稳定性、靶向性、疗效及安全性等方面依然存在诸多不足。新型ADC,如双特异性、位点特异性、双有效载荷和前药型ADC,通过同时结合2个不同抗原或表位、选择更稳定的连接子、与抗体特定氨基酸位点偶联、携带不同药物有效载荷以及采用前药策略等优化方法,在保留传统ADC作用特点的基础上,显著提高药物的稳定性、靶向性、疗效和安全性,能更好地满足临床治疗的需求。新型ADC可能会在未来的癌症治疗中发挥重要的作用。探讨新型ADC在癌症治疗中的进展并分析其优势与挑战,可为开发抗癌策略提供理论支持,为药物研发提供方向。
