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Changes in oral trace gas concentrations following orthognathic surgery and intermaxillary fixation: a case study using selected ion flow tube mass spectrometry 被引量:1
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作者 Brian M. Ross 《International Journal of Oral Science》 SCIE CAS CSCD 2011年第3期160-164,共5页
Orthognathic surgery is frequently accompanied by intermaxillary fixation. Intermaxillary fixation impedes the maintenance of effective oral hygiene and prolonged fixation can result in periodontal disease. A potentia... Orthognathic surgery is frequently accompanied by intermaxillary fixation. Intermaxillary fixation impedes the maintenance of effective oral hygiene and prolonged fixation can result in periodontal disease. A potential shorter term effect is the generation of oral malodour. It is unclear, however, as to how the production of malodorous compounds in the oral cavity is altered post-surgery. Oral air concentration of sulphur containing compounds, short chain organic acids, ammonia, isoprene and acetone were measured using selected ion flow tube-mass spectrometry in a patient who had undergone orthognathic surgery with subsequent intermaxillary fixation. Total sulphide levels rose approximately 5-fold during fixation with metal ties, with smaller increases recorded for the other compounds measured with the exception of isoprene which remained close to baseline levels. Organic acid levels declined markedly once elastic ties had replaced metal ties, with a lesser reduction being observed in sulphide levels, with both declining further after the commencement of a chlorhexidinecontaining mouthwash. These data suggest that bacterial generation of a variety of malodorous compounds increases markedly following intermaxillary fixation. This single case also suggests that the use of elastic ties and effective oral hygiene techniques, including the use of chlorhexidine mouthwash, may help ameliorate such post-surgical effects. 展开更多
关键词 oral malodour HALITOSIS oral hygiene breath analysis organic acids SULPHIDES mass spectrometry
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西帕依固龈液体外抑制致臭菌及防治口臭的效果评价 被引量:2
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作者 罗颖 丁一 +3 位作者 王萌 邓赟 朱硃 谢萍 《中国医药导刊》 2009年第2期278-279,282,共3页
目的:本研究通过体外抑菌和体内试验,评价西帕依固龈液对口腔主要致臭菌抑菌作用及体内防治半胱氨酸激发性口臭的效果,为其进一步在临床应用提供依据。方法:采用琼脂稀释法,测定西帕依固龈液对牙龈卟啉单胞菌(Pg)、中间普雷沃菌(Pi)、... 目的:本研究通过体外抑菌和体内试验,评价西帕依固龈液对口腔主要致臭菌抑菌作用及体内防治半胱氨酸激发性口臭的效果,为其进一步在临床应用提供依据。方法:采用琼脂稀释法,测定西帕依固龈液对牙龈卟啉单胞菌(Pg)、中间普雷沃菌(Pi)、具核梭杆菌(Fn)的最低抑菌浓度(MIC);对10例志愿者采用自身前后对照试验,观察四种干预措施(无干预、清水、西帕依固龈液、口泰)对半胱氨酸激发性口臭的最大值水平、各时间点下降百分比及口气值的下降曲线的影响,评价西帕依固龈液防治口臭的效果。结果:西帕依同龈液对Pg、Fn的MIC是的1mg/mL,对Pi的MIC是0.5 mg/mL;西帕依固龈液对半胱氨酸激发的口臭试验亦有显著的防治效果。结论:西帕依固龈液对口腔主要致臭菌具有明显的抑制作用,可以有效抑制半胱氨酸激发的口臭。 展开更多
关键词 西帕依同龈液 抑菌 防治 半胱氨酸激发试验 口臭
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