The major enrichment type of shale oil in the Chang 7_(3) shale of Upper Triassic Yanchang Formation in the Ordos Basin is unknown.This paper analyzes the organic matter transformation ratio,hydrocarbon expulsion effi...The major enrichment type of shale oil in the Chang 7_(3) shale of Upper Triassic Yanchang Formation in the Ordos Basin is unknown.This paper analyzes the organic matter transformation ratio,hydrocarbon expulsion efficiency and roof/floor sealing conditions of the Chang 7_(3) shale,and evaluates the major enrichment type of shale oil in this interval.The average organic matter transformation ratio of the Chang 7_(3) shale is about 45%;in other words,more than 50%of the organic matters have not transformed to hydrocarbons,and the lower the maturity,the greater the proportion of untransformed organic matters.The cumulative hydrocarbon expulsion efficiency of the transformed hydrocarbon is 27.5% on average,and the total proportion of untransformed organic matters plus retained hydrocarbons is greater than 70%.The relative hydrocarbon expulsion efficiency of the Chang 7_(3) shale is 60%on average,that is,about 40% of hydrocarbons retain in the shale.The Chang 7_(3) shale corresponds to Chang 7_(1+2) and Chang 8 sandstones as the roof and floor,respectively,and is further overlaid by Chang 6 shale,where extensive low porosity and low permeability–tight oil reservoirs have formed in the parts with relatively good porosity and permeability.Moreover,the Chang 7_(3) shale is tested to be in a negative pressure system(the pressure coefficient of 0.80–0.85).Therefore,the roof/floor sealing conditions of the Chang 7_(3) shale are poor.The retained hydrocarbons appear mostly in absorbed status,with low mobility.It is concluded that the medium–high mature shale oil is not the major enrichment type of shale oil in the Chang 7_(3) shale,but there may be enrichment opportunity for shale oil with good mobility in the areas where the sealing conditions are good without faults and fractures and oil reservoirs are formed off Chang 7_(1+2),Chang 6 and Chang 8.Furthermore,low–medium mature shale oil is believed to have great potential and is the major enrichment type of shale oil in the Chang 7_(3) shale.It is recommended to prepare relevant in-situ conversion technologies by pilot test and figure out the resource availability and distribution.展开更多
Changes in soil biological and biochemical properties under different land uses in the subtropical region of China were investigated in order to develop rational cultivation and fertilization management. A small water...Changes in soil biological and biochemical properties under different land uses in the subtropical region of China were investigated in order to develop rational cultivation and fertilization management. A small watershed of subtropical region of China was selected for this study. Land uses covered paddy fields, vegetable farming, fruit trees, upland crops, bamboo stands, and forestry. Soil biological and biochemical properties included soil organic C and nutrient contents, mineralization of soil organic C, and soil microbial biomass and community functional diversity. Soil organic C and total N contents, microbial biomass C and N, and respiration intensity under different land uses were changed in the following order: paddy fields (and vegetable farming) 〉 bamboo stands 〉 fruit trccs (and upland). The top surface (0-15 cm) paddy fields (and vegetable farming) were 76.4 and 80.8% higher in soil organic C and total N contents than fruit trees (and upland) soils, respectively. Subsurface paddy soils (15-30 cm) were 59.8 and 67.3% higher in organic C and total N than upland soils, respectively. Soil microbial C, N and respiration intensity in paddy soils (0-15 cm) were 6.36, 3.63 and 3.20 times those in fruit tree (and upland) soils respectively. Soil microbial metabolic quotient was in the order: fruit trees (and upland) 〉 forestry 〉 paddy fields. Metabolic quotient in paddy soils was only 47.7% of that in fruit tree (and upland) soils. Rates of soil organic C mineralization during incubation changed in the order: paddy fields 〉 bamboo stands 〉 fruit trees (and upland) and soil bacteria population: paddy fields 〉 fruit trees (and upland) 〉 forestry. No significant difference was found for fungi and actinomycetes populations. BIOLOG analysis indicated a changing order of paddy fields 〉 fruit trees (and upland) 〉 forestry in values of the average well cell development (AWCD) and functional diversity indexes of microbial community. Results also showed that the conversion from paddy fields to vegetable farming for 5 years resulted in a dramatic increase in soil available phosphorus content while insignificant changes in soil organic C and total N content due to a large inputs of phosphate fertilizers. This conversion caused 53, 41.5, and 41.3% decreases in soil microbial biomass C, N, and respiration intensity, respectively, while 23.6% increase in metabolic quotient and a decrease in soil organic C mineralization rate. Moreover, soil bacteria and actinomycetes populations were increased slightly, while fungi population increased dramatically. Functional diversity indexes of soil microbial community decreased significantly. It was concluded that land uses in the subtropical region of China strongly affected soil biological and biochemical properties. Soil organic C and nutrient contents, mineralization of organic C and functional diversity of microbial community in paddy fields were higher than those in upland and forestry. Overuse of chemical fertilizers in paddy fields with high fertility might degrade soil biological properties and biochemical function, resulting in deterioration of soil biological quality.展开更多
The technical feasibility of in situ upgrading technology to develop the enormous oil and gas resource potential in low-maturity shale is widely acknowledged.However,because of the large quantities of energy required ...The technical feasibility of in situ upgrading technology to develop the enormous oil and gas resource potential in low-maturity shale is widely acknowledged.However,because of the large quantities of energy required to heat shale,its economic feasibility is still a matter of debate and has yet to be convincingly demonstrated quantitatively.Based on the energy conservation law,the energy acquisition of oil and gas generation and the energy consumption of organic matter cracking,shale heat-absorption,and surrounding rock heat dissipation during in situ heating were evaluated in this study.The energy consumption ratios for different conditions were determined,and the factors that influence them were analyzed.The results show that the energy consumption ratio increases rapidly with increasing total organic carbon(TOC)content.For oil-prone shales,the TOC content corresponding to an energy consumption ratio of 3 is approximately 4.2%.This indicates that shale with a high TOC content can be expected to reduce the project cost through large-scale operation,making the energy consumption ratio after consideration of the project cost greater than 1.In situ heating and upgrading technology can achieve economic benefits.The main methods for improving the economic feasibility by analyzing factors that influence the energy consumption ratio include the following:(1)exploring technologies that efficiently heat shale but reduce the heat dissipation of surrounding rocks,(2)exploring technologies for efficient transformation of organic matter into oil and gas,i.e.,exploring technologies with catalytic effects,or the capability to reduce in situ heating time,and(3)establishing a horizontal well deployment technology that comprehensively considers the energy consumption ratio,time cost,and engineering cost.展开更多
In the era of Internet economics, e-business has become one of the most important strategic factors for enterprise development, so theoretical systems are needed to help enterprises develop e-business transformation s...In the era of Internet economics, e-business has become one of the most important strategic factors for enterprise development, so theoretical systems are needed to help enterprises develop e-business transformation strategies. A review of enterprise transformation theory identified five critical organization dimensions of e-business transformation, corporate strategy and vision transformation, organizational structure, product and market transformation, business process transformation, and corporate culture transformation. An e-business transformation process model was developed based on the five dimensions. This model can help enterprises to more effectively implement e-business transformation strategies.展开更多
The introduction of materials with dual-functionalities,i.e.,the catalytic(adsorption)features to inhibit shuttle effects at the cathode side,and the capability to facilitate homogenous Li-ion fluxes at the anode side...The introduction of materials with dual-functionalities,i.e.,the catalytic(adsorption)features to inhibit shuttle effects at the cathode side,and the capability to facilitate homogenous Li-ion fluxes at the anode side,is a promising strategy to realize high performance lithium-sulfur batteries(LSBs).Herein,a facile and rational organic“ligand-induced”(trimesic acid(TMA))transformation tactic is proposed,which achieves the regulation of electronic performance and d-band center of bimetallic oxides(NiFe_(2)O_(4))to promote bidirectional sulfur conversion kinetics and stabilize the Li plating/striping during the charge/discharge process.The battery assembled with NiFe_(2)O_(4)-TMA modified separator exhibits a remarkable initial specific capacity of 1476.6 mAh·g^(-1)at 0.1 C,outstanding rate properties(661.1 mAh·g^(-1)at 8.0 C),and excellent cycling ability.The“ligand-induced”transformation tactic proposed in this work will open a whole new possibility for tuning the electronic structure and d-band center to enhance the performance of LSBs.展开更多
Metal-organic frameworks(MOFs)have always been the focus of chemists due to their diverse structures,adjustable pore size and high stability since they came into being.In recent years,as one of the most significant ap...Metal-organic frameworks(MOFs)have always been the focus of chemists due to their diverse structures,adjustable pore size and high stability since they came into being.In recent years,as one of the most significant applications of MOFs porous materials,photocatalytic organic compounds transformation has made full-grown progress both in the preparation of the catalysts themselves and in the scope of specific applications.Herein,we summarize the research progress of MOFs catalysts for photocatalytic transformations of organic compounds in recent three years.Some outstanding works on the preparation and synthesis strategies of photocatalysts are introduced firstly,including internal optimization and modification of MOFs,POM@MOF composite and core-shell MOF@COF hybrids.The second part is about the application of diverse types of organic reactions,including dual-function organic reactions,catalytic oxidation reactions,comprehensive utilization of CO_(2) and degradation of organic pollutants.Besides,the development opportunities and some problems to be solved in this field are proposed.展开更多
The nanotechnology industry advances rapidly,and at the vanguard are the promising silver nanoparticles(Ag NPs),which have diverse applications.These nanometer-sized particles have been shown to inhibit the ability ...The nanotechnology industry advances rapidly,and at the vanguard are the promising silver nanoparticles(Ag NPs),which have diverse applications.These nanometer-sized particles have been shown to inhibit the ability of bacteria to produce adenosine triphosphate(ATP),a molecule necessary for chemical energy transport in cells.The antimicrobial properties of Ag NPs(and Ag+)make them valued antibacterial展开更多
The application of semiconductors-based photocatalysts in organic transformation has been limited by the low light utilization efficiency and the rapid recombination of photo-induced charge carriers.In this paper,we h...The application of semiconductors-based photocatalysts in organic transformation has been limited by the low light utilization efficiency and the rapid recombination of photo-induced charge carriers.In this paper,we have successfully fabricated a hollow cuboctahedral nanostructure(CNNCH),which is composed of N-doped carbon layer and CuO/NiO p-n heterojunctions.The hollow structure in CNNCH can effectively favor the light utilization through the multiple light reflection and scattering.The separation of photo-induced charge carriers can be highly improved by the exitence of charge transfer pathways between the p-n heterojunctions and semiconductor/N-doped carbon layer interfaces.Due to the above advantages,hollow cuboctahedral CNNCH as the photocatalyst has behaved high performance towards the photocatalytic cross-dehydrogenative coupling reaction.展开更多
Photocatalytic organic transformation is an efficient, energysaving and environmentally friendly strategy for organic synthesis. The key to developing a green and economical route for photocatalytic organic synthesis ...Photocatalytic organic transformation is an efficient, energysaving and environmentally friendly strategy for organic synthesis. The key to developing a green and economical route for photocatalytic organic synthesis lies in the construction of optimal photocatalysts. Covalent organic frameworks(COFs), a kind of porous crystalline materials with characteristics of high surface area, excellent porosity, and superior thermo-chemical stability, have driven people to explore their potential as photocatalysts in photocatalytic organic transformations by virtue of their structural versatility and designability. Furthermore, the insolubility of COFs makes it possible to recycle the catalysts by simple technical means. In recent years, researchers have made great efforts to develop both the design strategies of COFs as heterogeneous photocatalysts and the reaction types of photocatalytic organic transformations. In this review, we focus on the design of COF-based photocatalytic materials and analyze the influence factors of photocatalytic performance. Moreover, we summarize the application of COFbased photocatalysts in photocatalytic organic conversion. Finally, the perspectives on new opportunities and challenges in the field are discussed.展开更多
Tissue engineering(TE)is promising for the regeneration of failed organs.However,immune rejection,shortage of seed cells,and unintegrated blood vessels restrict the development and clinical application of TE.The last ...Tissue engineering(TE)is promising for the regeneration of failed organs.However,immune rejection,shortage of seed cells,and unintegrated blood vessels restrict the development and clinical application of TE.The last factor is the most challenging and intractable.Harnessing the mature blood vessel network in existing dispensable organs could be a powerful approach to effectively overcome the obstacles.After being remodeled to harbor an immunosuppressive and proregenerative niche,these potential target organs can be transformed into other organs with specific physiological functions,compensating the latter's failed native functions.Organ transformation,such as a hepatized spleen,represents an effective and encouraging TE strategy.In this review,we discuss the current development and obstacles of TE and its feasibility and superiority in organ transformation.展开更多
基金Supported by the National Natural Science Foundation of China(U22B6004).
文摘The major enrichment type of shale oil in the Chang 7_(3) shale of Upper Triassic Yanchang Formation in the Ordos Basin is unknown.This paper analyzes the organic matter transformation ratio,hydrocarbon expulsion efficiency and roof/floor sealing conditions of the Chang 7_(3) shale,and evaluates the major enrichment type of shale oil in this interval.The average organic matter transformation ratio of the Chang 7_(3) shale is about 45%;in other words,more than 50%of the organic matters have not transformed to hydrocarbons,and the lower the maturity,the greater the proportion of untransformed organic matters.The cumulative hydrocarbon expulsion efficiency of the transformed hydrocarbon is 27.5% on average,and the total proportion of untransformed organic matters plus retained hydrocarbons is greater than 70%.The relative hydrocarbon expulsion efficiency of the Chang 7_(3) shale is 60%on average,that is,about 40% of hydrocarbons retain in the shale.The Chang 7_(3) shale corresponds to Chang 7_(1+2) and Chang 8 sandstones as the roof and floor,respectively,and is further overlaid by Chang 6 shale,where extensive low porosity and low permeability–tight oil reservoirs have formed in the parts with relatively good porosity and permeability.Moreover,the Chang 7_(3) shale is tested to be in a negative pressure system(the pressure coefficient of 0.80–0.85).Therefore,the roof/floor sealing conditions of the Chang 7_(3) shale are poor.The retained hydrocarbons appear mostly in absorbed status,with low mobility.It is concluded that the medium–high mature shale oil is not the major enrichment type of shale oil in the Chang 7_(3) shale,but there may be enrichment opportunity for shale oil with good mobility in the areas where the sealing conditions are good without faults and fractures and oil reservoirs are formed off Chang 7_(1+2),Chang 6 and Chang 8.Furthermore,low–medium mature shale oil is believed to have great potential and is the major enrichment type of shale oil in the Chang 7_(3) shale.It is recommended to prepare relevant in-situ conversion technologies by pilot test and figure out the resource availability and distribution.
基金the National Natural Science Foundation of China (40471066) the Knowledge Innovation Program of the Chinese Academy of Sciences (KZCX3-SW-417).
文摘Changes in soil biological and biochemical properties under different land uses in the subtropical region of China were investigated in order to develop rational cultivation and fertilization management. A small watershed of subtropical region of China was selected for this study. Land uses covered paddy fields, vegetable farming, fruit trees, upland crops, bamboo stands, and forestry. Soil biological and biochemical properties included soil organic C and nutrient contents, mineralization of soil organic C, and soil microbial biomass and community functional diversity. Soil organic C and total N contents, microbial biomass C and N, and respiration intensity under different land uses were changed in the following order: paddy fields (and vegetable farming) 〉 bamboo stands 〉 fruit trccs (and upland). The top surface (0-15 cm) paddy fields (and vegetable farming) were 76.4 and 80.8% higher in soil organic C and total N contents than fruit trees (and upland) soils, respectively. Subsurface paddy soils (15-30 cm) were 59.8 and 67.3% higher in organic C and total N than upland soils, respectively. Soil microbial C, N and respiration intensity in paddy soils (0-15 cm) were 6.36, 3.63 and 3.20 times those in fruit tree (and upland) soils respectively. Soil microbial metabolic quotient was in the order: fruit trees (and upland) 〉 forestry 〉 paddy fields. Metabolic quotient in paddy soils was only 47.7% of that in fruit tree (and upland) soils. Rates of soil organic C mineralization during incubation changed in the order: paddy fields 〉 bamboo stands 〉 fruit trees (and upland) and soil bacteria population: paddy fields 〉 fruit trees (and upland) 〉 forestry. No significant difference was found for fungi and actinomycetes populations. BIOLOG analysis indicated a changing order of paddy fields 〉 fruit trees (and upland) 〉 forestry in values of the average well cell development (AWCD) and functional diversity indexes of microbial community. Results also showed that the conversion from paddy fields to vegetable farming for 5 years resulted in a dramatic increase in soil available phosphorus content while insignificant changes in soil organic C and total N content due to a large inputs of phosphate fertilizers. This conversion caused 53, 41.5, and 41.3% decreases in soil microbial biomass C, N, and respiration intensity, respectively, while 23.6% increase in metabolic quotient and a decrease in soil organic C mineralization rate. Moreover, soil bacteria and actinomycetes populations were increased slightly, while fungi population increased dramatically. Functional diversity indexes of soil microbial community decreased significantly. It was concluded that land uses in the subtropical region of China strongly affected soil biological and biochemical properties. Soil organic C and nutrient contents, mineralization of organic C and functional diversity of microbial community in paddy fields were higher than those in upland and forestry. Overuse of chemical fertilizers in paddy fields with high fertility might degrade soil biological properties and biochemical function, resulting in deterioration of soil biological quality.
文摘The technical feasibility of in situ upgrading technology to develop the enormous oil and gas resource potential in low-maturity shale is widely acknowledged.However,because of the large quantities of energy required to heat shale,its economic feasibility is still a matter of debate and has yet to be convincingly demonstrated quantitatively.Based on the energy conservation law,the energy acquisition of oil and gas generation and the energy consumption of organic matter cracking,shale heat-absorption,and surrounding rock heat dissipation during in situ heating were evaluated in this study.The energy consumption ratios for different conditions were determined,and the factors that influence them were analyzed.The results show that the energy consumption ratio increases rapidly with increasing total organic carbon(TOC)content.For oil-prone shales,the TOC content corresponding to an energy consumption ratio of 3 is approximately 4.2%.This indicates that shale with a high TOC content can be expected to reduce the project cost through large-scale operation,making the energy consumption ratio after consideration of the project cost greater than 1.In situ heating and upgrading technology can achieve economic benefits.The main methods for improving the economic feasibility by analyzing factors that influence the energy consumption ratio include the following:(1)exploring technologies that efficiently heat shale but reduce the heat dissipation of surrounding rocks,(2)exploring technologies for efficient transformation of organic matter into oil and gas,i.e.,exploring technologies with catalytic effects,or the capability to reduce in situ heating time,and(3)establishing a horizontal well deployment technology that comprehensively considers the energy consumption ratio,time cost,and engineering cost.
文摘In the era of Internet economics, e-business has become one of the most important strategic factors for enterprise development, so theoretical systems are needed to help enterprises develop e-business transformation strategies. A review of enterprise transformation theory identified five critical organization dimensions of e-business transformation, corporate strategy and vision transformation, organizational structure, product and market transformation, business process transformation, and corporate culture transformation. An e-business transformation process model was developed based on the five dimensions. This model can help enterprises to more effectively implement e-business transformation strategies.
基金This work was financially supported by the Natural Science Foundation of Guangdong Province(No.2019A1515011727)the Open Fund of the Guangdong Provincial Key Laboratory of Advance Energy Storage Materials.We also acknowledge the fund of Natural Science Foundation of Hubei Province(No.2021CFB011)the National Natural Science Foundation of China(Nos.52104309 and 52161033).
文摘The introduction of materials with dual-functionalities,i.e.,the catalytic(adsorption)features to inhibit shuttle effects at the cathode side,and the capability to facilitate homogenous Li-ion fluxes at the anode side,is a promising strategy to realize high performance lithium-sulfur batteries(LSBs).Herein,a facile and rational organic“ligand-induced”(trimesic acid(TMA))transformation tactic is proposed,which achieves the regulation of electronic performance and d-band center of bimetallic oxides(NiFe_(2)O_(4))to promote bidirectional sulfur conversion kinetics and stabilize the Li plating/striping during the charge/discharge process.The battery assembled with NiFe_(2)O_(4)-TMA modified separator exhibits a remarkable initial specific capacity of 1476.6 mAh·g^(-1)at 0.1 C,outstanding rate properties(661.1 mAh·g^(-1)at 8.0 C),and excellent cycling ability.The“ligand-induced”transformation tactic proposed in this work will open a whole new possibility for tuning the electronic structure and d-band center to enhance the performance of LSBs.
基金National Natural Science Foundation of China(21701078)for the financial support of this work。
文摘Metal-organic frameworks(MOFs)have always been the focus of chemists due to their diverse structures,adjustable pore size and high stability since they came into being.In recent years,as one of the most significant applications of MOFs porous materials,photocatalytic organic compounds transformation has made full-grown progress both in the preparation of the catalysts themselves and in the scope of specific applications.Herein,we summarize the research progress of MOFs catalysts for photocatalytic transformations of organic compounds in recent three years.Some outstanding works on the preparation and synthesis strategies of photocatalysts are introduced firstly,including internal optimization and modification of MOFs,POM@MOF composite and core-shell MOF@COF hybrids.The second part is about the application of diverse types of organic reactions,including dual-function organic reactions,catalytic oxidation reactions,comprehensive utilization of CO_(2) and degradation of organic pollutants.Besides,the development opportunities and some problems to be solved in this field are proposed.
文摘The nanotechnology industry advances rapidly,and at the vanguard are the promising silver nanoparticles(Ag NPs),which have diverse applications.These nanometer-sized particles have been shown to inhibit the ability of bacteria to produce adenosine triphosphate(ATP),a molecule necessary for chemical energy transport in cells.The antimicrobial properties of Ag NPs(and Ag+)make them valued antibacterial
基金This work was supported by the Natural Science Foundation of Jiangsu Province(Nos.BK20211549 and BK20191466)and Xuzhou City(No.KC20061)the National Natural Science Foundation of China(No.22072135).
文摘The application of semiconductors-based photocatalysts in organic transformation has been limited by the low light utilization efficiency and the rapid recombination of photo-induced charge carriers.In this paper,we have successfully fabricated a hollow cuboctahedral nanostructure(CNNCH),which is composed of N-doped carbon layer and CuO/NiO p-n heterojunctions.The hollow structure in CNNCH can effectively favor the light utilization through the multiple light reflection and scattering.The separation of photo-induced charge carriers can be highly improved by the exitence of charge transfer pathways between the p-n heterojunctions and semiconductor/N-doped carbon layer interfaces.Due to the above advantages,hollow cuboctahedral CNNCH as the photocatalyst has behaved high performance towards the photocatalytic cross-dehydrogenative coupling reaction.
基金supported by the National Natural Science Foundation of China (Nos.21774040,61435005,21805110).
文摘Photocatalytic organic transformation is an efficient, energysaving and environmentally friendly strategy for organic synthesis. The key to developing a green and economical route for photocatalytic organic synthesis lies in the construction of optimal photocatalysts. Covalent organic frameworks(COFs), a kind of porous crystalline materials with characteristics of high surface area, excellent porosity, and superior thermo-chemical stability, have driven people to explore their potential as photocatalysts in photocatalytic organic transformations by virtue of their structural versatility and designability. Furthermore, the insolubility of COFs makes it possible to recycle the catalysts by simple technical means. In recent years, researchers have made great efforts to develop both the design strategies of COFs as heterogeneous photocatalysts and the reaction types of photocatalytic organic transformations. In this review, we focus on the design of COF-based photocatalytic materials and analyze the influence factors of photocatalytic performance. Moreover, we summarize the application of COFbased photocatalysts in photocatalytic organic conversion. Finally, the perspectives on new opportunities and challenges in the field are discussed.
基金Fundo para o Desenvolvimento das Ciências e da Tecnologia(the Science and Technology Development Fund,Macao SAR),Grant/Award Number:FDCT 0060/2020/AGJSpanish Ministry of Health–Instituto de Salud Carlos III,Grant/Award Number:FIS PI20/00220+4 种基金Universidade de Macao(the University of Macao Research Committee),Grant/Award Number:MYRG2020‐00084‐ICMSNatural Science Foundation of Jiangsu Province,Grant/Award Number:BK20200318Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung(the Swiss National Science Foundation),Grant/Award Number:310030_185219&320030_189252the Stiftung für Leberkrankheiten(Swiss Liver Foundation)National Natural Science Foundation of China,Grant/Award Numbers:31961160701,31971309,and 32001069。
文摘Tissue engineering(TE)is promising for the regeneration of failed organs.However,immune rejection,shortage of seed cells,and unintegrated blood vessels restrict the development and clinical application of TE.The last factor is the most challenging and intractable.Harnessing the mature blood vessel network in existing dispensable organs could be a powerful approach to effectively overcome the obstacles.After being remodeled to harbor an immunosuppressive and proregenerative niche,these potential target organs can be transformed into other organs with specific physiological functions,compensating the latter's failed native functions.Organ transformation,such as a hepatized spleen,represents an effective and encouraging TE strategy.In this review,we discuss the current development and obstacles of TE and its feasibility and superiority in organ transformation.