Following fertilization in mammals, the zygote initiates the developmental program, which has a transient capacity to generate cell types of both embryonic and extraembryonic lineages, which is defined as totipotency ...Following fertilization in mammals, the zygote initiates the developmental program, which has a transient capacity to generate cell types of both embryonic and extraembryonic lineages, which is defined as totipotency (Condic, 2014). In mice,only zygotes and blastomeres of 2-cell stage embryos are considered totipotent, since they have the ability to develop into a full展开更多
基金supported by the National Natural Science Foundation of China (Nos. 31621004 and 81571356)the Key Research Projects of the Frontier Science of the Chinese Academy of Sciences (QYZDY-SSWSMC002)+1 种基金the Key Deployment Projects of the Chinese Academy of Sciences (ZDRW-ZS-2017-5)the Youth Innovation Promotion Association CAS (No. 2017113)
文摘Following fertilization in mammals, the zygote initiates the developmental program, which has a transient capacity to generate cell types of both embryonic and extraembryonic lineages, which is defined as totipotency (Condic, 2014). In mice,only zygotes and blastomeres of 2-cell stage embryos are considered totipotent, since they have the ability to develop into a full
