The Internet of Things(IoT)has witnessed a significant surge in adoption,particularly through the utilization of Wireless Sensor Networks(WSNs),which comprise small internet-connected devices.These deployments span va...The Internet of Things(IoT)has witnessed a significant surge in adoption,particularly through the utilization of Wireless Sensor Networks(WSNs),which comprise small internet-connected devices.These deployments span various environments and offer a multitude of benefits.However,the widespread use of battery-powered devices introduces challenges due to their limited hardware resources and communication capabilities.In response to this,the Internet Engineering Task Force(IETF)has developed the IPv6 Routing Protocol for Low-power and Lossy Networks(RPL)to address the unique requirements of such networks.Recognizing the critical role of RPL in maintaining high performance,this paper proposes a novel approach to optimizing power consumption.Specifically,it introduces a developed sensor motes topology integrated with a Radio Duty Cycling(RDC)mechanism aimed at minimizing power usage.Through rigorous analysis,the paper evaluates the power efficiency of this approach through several simulations conducted across different network topologies,including random,linear,tree,and elliptical topologies.Additionally,three distinct RDC mechanisms—CXMAC,ContikiMAC,and NullRDC—are investigated to assess their impact on power consumption.The findings of the study,based on a comprehensive and deep analysis of the simulated results,highlight the efficiency of ContikiMAC in power conservation.This research contributes valuable insights into enhancing the energy efficiency of RPL-based IoT networks,ultimately facilitating their widespread deployment and usability in diverse environments.展开更多
Background Out-of-hospital patients presenting with atypical chest pain and complete left bundle branch block(LBBB)have to be stratified for the presence of coronary artery disease and the risk of developing heart fai...Background Out-of-hospital patients presenting with atypical chest pain and complete left bundle branch block(LBBB)have to be stratified for the presence of coronary artery disease and the risk of developing heart failure(HF).We investigated the pro-gnostic role of coronary CT-angiography(CTA)and echocardiographic global longitudinal strain(GLS)in those patients in a mid-term follow-up.Methods Out-of-hospital patients with LBBB underwent echocardiography and a 64-slice CT angiography were evaluated ret-rospectively.Development of HF or a cardiovascular death were the events scheduled.Results Seventy-eight patients(32 female;mean age:66.0±10.4 years were enrolled.During a follow-up of 33 months(IQR:17-77),one patient(1.5%)experienced a cardiovascular death,14 patients(17.9%)required urgent outpatient visits due to acute de-compensated HF(12 hospitalizations).Echocardiography showed a slightly reduced left ventricular ejection fraction(LVEF)(50.0%±9.8%)and GLS within the normal range(-16.2%±4.1%).CTA analysis showed coronary stenosis>50%in 28 patients(35.9%).A high Agatston score(>100)was observed in 29.5%.Notably,25 patients(32.1%)were diagnosed with left main coron-ary artery disease and 15 patients(16.7%)underwent revascularization during the follow up.Significant associations were ob-served between events and LVEF(P=0.001),diastolic dysfunction grade≥2(P=0.02),GLS(P<0.001),multiple coronary stenos-is(P=0.04)and Agatston score(P=0.05).Multivariate analysis confirmed the relationships with LVEF(R^(2)=0.89,P<0.001),dia-stolic dysfunction(R^(2)=3.30,P=0.04),GLS(R^(2)=1.43,P<0.001),and Agatston score(R^(2)=1.01,P=0.05).Conclusions In patients with complete LBBB,CTA and GLS identified those at a high risk of development HF.展开更多
This study presents a two-echelon inventory routing problem (2E-IRP) with an end-of-tour replenishment (ETR) policy whose distribution network consists of a supplier, several distribution centers (DCs) and several ret...This study presents a two-echelon inventory routing problem (2E-IRP) with an end-of-tour replenishment (ETR) policy whose distribution network consists of a supplier, several distribution centers (DCs) and several retailers on a multi-period planning horizon. A formulation of the problem based on vehicle indices is proposed in the form of a mixed integer linear program (MILP). The mathematical model of the problem is solved using a branch and cut (B&C) algorithm. The results of the tests are compared to the results of a branch and price (B&P) algorithm from the literature on 2E-IRP with a classical distribution policy. The results of the tests show that the B&C algorithm solves 197 out of 200 instances (98.5%). The comparison of the B&C and B&P results shows that 185 best solutions are obtained with the B&C algorithm on 197 instances (93.9%). Overall, the B&C algorithm achieves cost reductions ranging from 0.26% to 41.44% compared to the classic 2E-IRP results solved with the B&P algorithm, with an overall average reduction of 18.08%.展开更多
To improve the amylose content(AC)and resistant starch content(RSC)of maize kernel starch,we employed the CRISPR/Cas9 system to create mutants of starch branching enzyme I(SBEI)and starch branching enzyme IIb(SBEIIb)....To improve the amylose content(AC)and resistant starch content(RSC)of maize kernel starch,we employed the CRISPR/Cas9 system to create mutants of starch branching enzyme I(SBEI)and starch branching enzyme IIb(SBEIIb).A frameshift mutation in SBEI(E1,a nucleotide insertion in exon 6)led to plants with higher RSC(1.07%),lower hundred-kernel weight(HKW,24.71±0.14 g),and lower plant height(PH,218.50±9.42 cm)compared to the wild type(WT).Like the WT,E1 kernel starch had irregular,polygonal shapes with sharp edges.A frameshift mutation in SBEIIb(E2,a four-nucleotide deletion in exon 8)led to higher AC(53.48%)and higher RSC(26.93%)than that for the WT.E2 kernel starch was significantly different from the WT regarding granule morphology,chain length distribution pattern,X-ray diffraction pattern,and thermal characteristics;the starch granules were more irregular in shape and comprised typical B-type crystals.Mutating SBEI and SBEIIb(E12)had a synergistic effect on RSC,HKW,PH,starch properties,and starch biosynthesis-associated gene expression.SBEIIa,SS1,SSIIa,SSIIIa,and SSIIIb were upregulated in E12 endosperm compared to WT endosperm.This study lays the foundation for rapidly improving the starch properties of elite maize lines.展开更多
Canopy and branch architectures in high-density orchards can be crucial in production and fruit quality. The influence of two canopy orientations (Upright and Tilted) in combination with two arm (branch) architectures...Canopy and branch architectures in high-density orchards can be crucial in production and fruit quality. The influence of two canopy orientations (Upright and Tilted) in combination with two arm (branch) architectures (Shortened or Overlapped) on tree growth, yield components, fruit quality, and leaf mineral nutrients in an “Aztec Fuji” apple (Malus domestica Bork.) high-density orchard was studied over five years. Tilted trees with shortened arm configuration (TilShArm) always had significantly larger trunk cross-sectional area (TCSA) than Upright trees with an Overlapped arm configuration (UpOverArm) every year from 2012 to 2016. Trees with a TilShArm system had more cumulative fruit per tree than those with an Upright orientation. Trees with a tilted canopy (TilShArm and TilOverArm) tended to have higher yield per tree and yield per hectare than those with an upright system. Trees with a TilShArm system were more precocious and had more yield per tree than those with an upright canopy orientation in 2012. When values were polled over five years, trees with an upright canopy-shortened arm system (UpShArm) treatment had a lower biennial bearing index (BBI) than those with an upright canopy-overlapped system (UpOverArm). Trees receiving an arm shortening (UpShArm or TilShArm) configuration often had larger fruits than those with overlapped arms (UpOverArm and TilOverArm). Fruit from trees receiving an UpOverArm had higher fruit firmness than those from trees with other canopy-branch arrangements at harvest due to their smaller size. Fruit from trees with a TilShArm and TilOverArm had significantly higher water core and bitter pit but lower sunburn than trees with an upright canopy (UpShArm and UpOverArm). Leaves from trees with an UpOverArm canopy-branch configuration had the lowest leaf Ca but the highest leaf K and Fe concentrations among all treatments.展开更多
Let{Z_(n)}_(n)≥0 be a critical or subcritical d-dimensional branching random walk started from a Poisson random measure whose intensity measure is the Lebesugue measure on R^(d).Denote by R_(n):=sup{u>0:Z_(n)({x∈...Let{Z_(n)}_(n)≥0 be a critical or subcritical d-dimensional branching random walk started from a Poisson random measure whose intensity measure is the Lebesugue measure on R^(d).Denote by R_(n):=sup{u>0:Z_(n)({x∈R^(d):∣x∣<u})=0}the radius of the largest empty ball centered at the origin of Z_(n).In this work,we prove that after suitable renormalization,Rn converges in law to some non-degenerate distribution as n→∞.Furthermore,our work shows that the renormalization scales depend on the offspring law and the dimension of the branching random walk.This completes the results of Révész[13]for the critical binary branching Wiener process.展开更多
Development of pore structures of activated carbon(AC)from activation of biomass with ZnCl_(2) relies on content and structure of cellulose/hemicellulose in the feedstock.Thermal pretreatment of biomass could induce d...Development of pore structures of activated carbon(AC)from activation of biomass with ZnCl_(2) relies on content and structure of cellulose/hemicellulose in the feedstock.Thermal pretreatment of biomass could induce dehydration and/or aromatization to change the structure of cellulose/hemicellulose.This might interfere with evolution of structures of AC,which was investigated herein via thermal pretreatment of willow branch(WB)from 200 to 360℃and the subsequent activation with ZnCl_(2) at 550℃.The results showed that thermal pretreatment at 360℃(WB-360)could lead to substantial pyrolysis to form biochar,with a yield of 31.9%,accompanying with nearly complete destruction of cellulose crystals and remarkably enhanced aromatic degree.However,cellulose residual in WB-360 could still be activated to form AC-360 with specific surface area of 1837.9 m~2·g^(-1),which was lower than that in AC from activation of untreated WB(AC-blank,2077.8 m~2·g^(-1)).Nonetheless,the AC-200 from activation of WB-200 had more developed pores(2113.9 m~2·g^(-1))and superior capability for adsorption of phenol,due to increased permeability of ZnCl_(2) to the largely intact cellulose structure in WB-200.The thermal pretreatment did increase diameters of micropores of AC but reduced the overall yield of AC(26.8%for AC-blank versus 18.0%for AC-360),resulting from accelerated cracking but reduced intensity of condensation.In-situ infrared characterization of the activation showed that ZnCl_(2) mainly catalyzed dehydration,dehydrogenation,condensation,and aromatization but not cracking,suppressing the formation of derivatives of cellulose and lignin in bio-oil.The thermal pretreatment formed phenolic-OH and C=O with higher chemical innerness,which changed the reaction network in activation,shifting morphology of fibrous structures in AC-blank to“melting surface”in AC-200 or AC-280.展开更多
Mantle branch structure is the third tectonic unit of multiple evolution of a mantle branch. It is not only the main mechanism of intercontinental orogeny, but also an important ore-forming and ore-control structure. ...Mantle branch structure is the third tectonic unit of multiple evolution of a mantle branch. It is not only the main mechanism of intercontinental orogeny, but also an important ore-forming and ore-control structure. Studies on geotectonic evolution, regional geological characteristics and oreforming and ore-control structures have shown that since the Mesozoic the Da Hinggan Mts. region has entered a typical intercontinental orogenic stage, and it is closely related to mantle branch activities. The south-central segment of the Da Hinggan Mts. is a typical mantle branch structure and possesses obvious magmatic-metamorphic complexes in the core, detachment slip beds in the periphery and overlapped fault depression basins. Moreover, all of these are the principal factors leading to ore formation and ore control in the region. This paper also further explores the mechanism of mineralization in the south-central segment of the Da Hinggan, summaries the rules of mineralization, puts forward the models of mineralization and points out future ore-exploring orientation.展开更多
Using observational data of Argos satellite-tracked drifters from 1988 to 2012, we analyzed seasonal characteristics of the surface Kuroshio branch(KB) intrusion into the South China Sea(SCS). The analysis results are...Using observational data of Argos satellite-tracked drifters from 1988 to 2012, we analyzed seasonal characteristics of the surface Kuroshio branch(KB) intrusion into the South China Sea(SCS). The analysis results are as follows.The surface KB originates from the southern Balintang Channel(BLTC) and Babuyan Channel(BBYC). It begins in late September, reaches peak strength in November–December, and declines at the end of March. The mean speed of drifters along the KB path during their traverse of the Luzon Strait(LS) was 43% faster than during the two days before entering the LS for the flow originating from the southern BLTC, but there was a 24% increase in speed for the flow from the BBYC. The observations show that in winter, monthly-mean sea-level anomalies(SLAs) were positive southwest of Taiwan Island and extended to the northern LS. The SLAs were negative northwest of Luzon Island and extended to the southern LS, which acted like a pump, forcing a part of Kuroshio water westward into the SCS. The condition under which the KB forms was solved by a set of simplified motion equations. The results indicate that whether the KB can form depends upon the sea-level gradient at the central LS and region to the west, as well as the location, speed and direction of Kuroshio surface water when it enters the LS.展开更多
Objective The eastern extending range of the Paleo-Tethys Ocean in southwest China has always been focused and controversial. At the beginning of this century some scholars proposed that the Paleo-Tethys Branch Ocean...Objective The eastern extending range of the Paleo-Tethys Ocean in southwest China has always been focused and controversial. At the beginning of this century some scholars proposed that the Paleo-Tethys Branch Ocean may extend to the Babu-Pingxiang and Cengxi areas along the stouthwestern margin of the South China Block (Cai and Zhang, 2009). However, the pivotal proof of Late Paleozoic ophoilite and magmatic rocks was absent or sporadical in the Guangxi Zhuang Autonomous Region, resulting in insufficient evidence to support this viewpoint. For the first time this work reported the Late Devonian tuff in the Qinzhou area in the south of the Guangxi Zhuang Autonomous Region and conducted zircon U-Pb dating on it in order to constrain the extension of the Paleo-Tethys Ocean in the South China Block.展开更多
AIM:To identify factors contributing to visual improvement after treatment of macular edema(ME)secondary to branch retinal vein occlusion(BRVO),and to assess the interaction between laser therapy and intravitreal rani...AIM:To identify factors contributing to visual improvement after treatment of macular edema(ME)secondary to branch retinal vein occlusion(BRVO),and to assess the interaction between laser therapy and intravitreal ranibizumab(IVR).METHODS:We retrospectively reviewed the medical records of patients who had been treated for BRVO-related ME at our hospital.Records were traceable for at least 12 mo,and evaluated factors included age,sex,medical history,smoking history,treatment methods,foveal hemorrhage,and change in visual acuity.Treatments included laser therapy,IVR,sub-Tenon’s capsule injection of triamcinolone(STTA),a combination,or no intervention.Multivariate logistic regression analysis and interaction terms were used to assess the clinical efficacy of the treatments,and odds ratios(OR)and 95%confidence intervals(CI)were calculated.RESULTS:Seventy-three patients(34 men,39 women;73 eyes)with a mean age of 69.4±12.1 y were included.Patients who underwent IVR monotherapy,laser monotherapy,and STTA+laser had significantly higher best corrected visual acuity at 12 mo compared to baseline(P<0.001,<0.001,and 0.019,respectively).Logistic regression analysis without interaction terms found that IVR was a significant visual acuity recovery factor(adjusted OR:3.89,95%CI:1.25-12.1,P=0.019).Adjusted OR using an interaction model by logistic regression was 16.6(95%CI:2.54-108.47,P=0.003)with IVR treatment,and 8.25(95%CI:1.34-50.57,P=0.023)with laser treatment.No interaction was observed(adjusted OR:0.07,95%CI:0.01-0.75,P=0.029).CONCLUSION:IVR contributes to improvements in visual acuity at 12 mo in ME secondary to BRVO.No interaction is observed between laser therapy and IVR treatments.展开更多
Background: It is crucial for the army to know the prevalence of obstructive sleep apnea(OSA) syndrome in activeduty army personnel. Little information has been reported on the prevalence of OSA and clinical features ...Background: It is crucial for the army to know the prevalence of obstructive sleep apnea(OSA) syndrome in activeduty army personnel. Little information has been reported on the prevalence of OSA and clinical features in activeduty army personnel. This study was aimed to estimate the prevalence of snoring and risk of developing OSA in activeduty army personnel in Thailand and to identify the co-morbidities of OSA. In total, 1107 participants who were aged20–60 years and were deployed to the three southernmost provinces of Thailand were enrolled. All the participants completed the Phramongkutklao(PMK) Hospital OSA Questionnaire that was modified and validated from the Berlin Questionnaire and underwent physical examination. The participants were 1107 active-duty army personnel in the three southernmost provinces of Thailand, both males and females, aged 20–60 years.Methods: The PMK OSA Questionnaire was used to assess the risk of OSA together with interviewing for snoring,fatigue, falling asleep and day-time sleepiness. Physical examination of the neck, chest and hip circumference,and height was performed. Information concerning physical training, co-morbid diseases, smoking and alcoholic consumption was collected.Results: The prevalence of snoring was 58.5, and 4.8% met the PMK OSA Questionnaire criteria, thus indicating a high risk of OSA. The information obtained indicated that laryngopharyngeal reflux(LPR), current smoking and alcoholic consumption were significantly higher in the high-risk OSA group.Conclusions: Early detection and treatment of OSA in active-duty army personnel are imperative. Physical examination and polysomnography can be used to reveal the high-risk group. High body mess index(BMI), laryngopharyngeal reflux, current smoking and alcoholic consumption are modifiable factors for OSA and are avoidable. A policy to decrease the BMI and risk of LPR, as well as to stop smoking and alcoholic consumption, should be applied.展开更多
The general form of the north-branch of the Changjiang River mouth has changed much as a result of the change of the main stream lines of the Nantong reach of the Changjiang River and the influence of human activities...The general form of the north-branch of the Changjiang River mouth has changed much as a result of the change of the main stream lines of the Nantong reach of the Changjiang River and the influence of human activities since 1915. By the 1930s, the main stream lines of the Nantong reach of the Changjiang River has shifted to the Tongzhou Bar west channel. The north-branch at the Changjiang River mouth has become atrophic because of Tongzhou Bar east channel's deposition. After 1958, Toughal Bar and Jiangxin Bar were exploited. And in 1970, the north channel of Jiangxin Bar was blocked up. All these things make the water of the north-branch more difficult to pass through. It leads to the decline of the total discharge percentage of the north-branch. And it causes the rising tide to go back to the south-branch. However, since 1978, with the development of Tongzhou Bar east channel and its left bank being scoured, the water amount of the north-branch has been increasing. And the water,load and salt of going back to the south-branch has been becoming less.展开更多
The Fifteenth Natlonal Con-gress,a very important andgrand trans—century meeting inthe history Of CCP,was inaugu-rated in Beijing on September 12,1997. Guangdong Customs have sentrepresentatives to attend the Party’...The Fifteenth Natlonal Con-gress,a very important andgrand trans—century meeting inthe history Of CCP,was inaugu-rated in Beijing on September 12,1997. Guangdong Customs have sentrepresentatives to attend the Party’sCongress for the first time in his-tory.Among the two representa-tives is Liu Wenjie,director ofGuangdong CUStoms Branch Of-fice and of Guangzhou Customs.On September 23 after conclusionof the Coilgress,this reporter inte-Viewed directory Liu Wenjie in展开更多
The features of branching and growth studied included height, diameter at breast height (DBH), total number of branches, annual height growth, annual branch elongation in the year of elongating, annual branch number f...The features of branching and growth studied included height, diameter at breast height (DBH), total number of branches, annual height growth, annual branch elongation in the year of elongating, annual branch number for four consecutive years, diameter of branches of different ages, and diameter of stem where branch-whorl originates. For features of total growth and overall branching, no significant differences were found between families, except for DBH. For annual features, no significant differences were found in annual stem height growth, annual branch elongation in the year of elongation and diameter of branches. In the last four years, differences in number of branches were not significant in the first two years but were significant in the last two year; differences in stem diameter where branch-whorls grow were significant for the four consecutive years. Trend of annual growth and branching features of families can be divided into three types as increasing type, stable type and fluctuating type. Most of families have an increasing type with respect of annual height growth and annual branch elongation, while most families belong to a fluctuating type with annual branch number. The results indicated that in the fifth year after planted in seedling seed orchard, differences between families were mostly insignificant. This result may have two main explanations: one is the growth rhyme in early ages of Masson pine, the other one is the complex paternal components to form the open-pollinated families. Family selection seemed to be not useful based on the result. It is suggested to select some of families in the nursery instead of to use all the families when establishing seedling seed orchards with open-pollinated families from plus-trees.展开更多
ObjectiveThe thesis aims at investigating the distribution and structural characteristics of various branches in canopy of Korla fragrant pear. MethodStatistic work and analysis were conducted on the numbers and distr...ObjectiveThe thesis aims at investigating the distribution and structural characteristics of various branches in canopy of Korla fragrant pear. MethodStatistic work and analysis were conducted on the numbers and distribution characteristics of various branches in each cubic lattice by using the canopy cellular method. ResultThe results showed that: The total number of scaffold branches of evacuation layered tree shape was 97, which mainly distributed in the lower layer and middle part of the canopy; the total number of scaffold branches of open-center tree shape was 94, which mainly distributed in the lower layer and middle part of the canopy. The total number of annual branches of evacuation layered tree shape was 3 920, which mainly distributed in the middle layer and outer part of the canopy; and the total number of annual branches of the open-center tree shape was 3 183, which mainly distributed in middle layer and outer part of the canopy. The total number of perennial branches of evacuation layered tree shape was 2 184, which mainly distributed in lower layer and outer part of the canopy; the total number of perennial branches of open-center tree shape was 1 444, which mainly distributed in middle layer and outer part of the canopy. ConclusionThe total number and the distribution positions of scaffold branches in the canopy of each tree shape were basically the same. The total numbers of annual branches of the two kinds of tree shapes were different, but the distribution positions were basically the same. The total numbers and the distribution positions of perennial branches in the canopy of the two kinds of tree shapes were different.展开更多
Based on the natural resources in Ganzi Tibetan Autonomous Prefecture, screening experiment of strains and nutrient sources for culture of Armillariella mellea rhizomoph branch was carried out with 3 strains of A. mel...Based on the natural resources in Ganzi Tibetan Autonomous Prefecture, screening experiment of strains and nutrient sources for culture of Armillariella mellea rhizomoph branch was carried out with 3 strains of A. mellea, 2 types of main nutrient sources and 3 kinds of auxiliary nutrient sources. Total 18 treatments were designed. The results showed that with the A. mellea strain separated from the tubers of wild Gastrodia elata BI. by tissue isolation as mother strain, the shrubs such as Prunus tatsienensis Batal and Quercus spinosa David ex Franch as the main nutrient sources, and the agricultural products such as corn and potato as the supplementary nutrient sources, the growth of A. mellea rhizomoph branch was best in bottle.展开更多
[Objective] The aim was to construct promoter of maize starch-branching enzyme sbe Ⅱb gene specifically expressed in seed.[Method] The promoter sequence of maize starch-branching enzyme sbe Ⅱb gene was amplified by ...[Objective] The aim was to construct promoter of maize starch-branching enzyme sbe Ⅱb gene specifically expressed in seed.[Method] The promoter sequence of maize starch-branching enzyme sbe Ⅱb gene was amplified by LA-PCR and then cloned into pMD18-T vector.Subsequently,the promoter was cloned into pBI121 vector to construct plant expression vector pBI121-sbe Ⅱb.Recombinant plasmid pSBE-GUS was constructed by connecting GUS gene into pBI121-sbe Ⅱb and transformed into tobacco mediated by Agrobacterium tumefaciens,before detection by PCR and Southern blot.The biochemical analysis and fluorescence detection of GUS activity were performed in different parts of the tobacco by Gene Gun Method and Agrobacterium tumefaciens transformation respectively.[Result] The homology between promoter sequence cloned in this experiment and the corresponding sequence announced in the GenBank reached 98.52%.Four transformed tobaccos were obtained by PCR and Southern blot after co-culture and selective culture.A small number of blue spots appeared in leaves,and the spots could barely been seen in the stems and roots,while a large number of blue spots were found in seeds.So,it could be concluded that the promoter of sbeⅡb gene was specifically expressed in seeds.[Conclusion] Promoter of maize starch branching enzyme sbe Ⅱb specifically expressed in seeds was successfully cloned.展开更多
A parameter estimation algorithm of the continuous hidden Markov model isintroduced and the rigorous proof of its convergence is also included. The algorithm uses theViterbi algorithm instead of K-means clustering use...A parameter estimation algorithm of the continuous hidden Markov model isintroduced and the rigorous proof of its convergence is also included. The algorithm uses theViterbi algorithm instead of K-means clustering used in the segmental K-means algorithm to determineoptimal state and branch sequences. Based on the optimal sequence, parameters are estimated withmaximum-likelihood as objective functions. Comparisons with the traditional Baum-Welch and segmentalK-means algorithms on various aspects, such as optimal objectives and fundamentals, are made. Allthree algorithms are applied to face recognition. Results indicate that the proposed algorithm canreduce training time with comparable recognition rate and it is least sensitive to the training set.So its average performance exceeds the other two.展开更多
BACKGROUND Left bundle branch pacing(LBBP)is a novel pacing modality of cardiac resynchronization therapy(CRT)that achieves more physiologic native ventricular activation than biventricular pacing(BiVP).AIM To explore...BACKGROUND Left bundle branch pacing(LBBP)is a novel pacing modality of cardiac resynchronization therapy(CRT)that achieves more physiologic native ventricular activation than biventricular pacing(BiVP).AIM To explore the validity of electromechanical resynchronization,clinical and echocardiographic response of LBBP-CRT.METHODS Systematic review and Meta-analysis were conducted in accordance with the standard guidelines as mentioned in detail in the methodology section.RESULTS In our analysis,the success rate of LBBP-CRT was determined to be 91.1%.LBBP CRT significantly shortened QRS duration,with significant improvement in echocardiographic parameters,including left ventricular ejection fraction,left ventricular end-diastolic diameter and left ventricular end-systolic diameter in comparison with BiVP-CRT.CONCLUSION A significant reduction in New York Heart Association class and B-type natriuretic peptide levels was also observed in the LBBP-CRT group vs BiVP-CRT group.Lastly,the LBBP-CRT cohort had a reduced pacing threshold at follow-up as compared to BiVP-CRT.展开更多
文摘The Internet of Things(IoT)has witnessed a significant surge in adoption,particularly through the utilization of Wireless Sensor Networks(WSNs),which comprise small internet-connected devices.These deployments span various environments and offer a multitude of benefits.However,the widespread use of battery-powered devices introduces challenges due to their limited hardware resources and communication capabilities.In response to this,the Internet Engineering Task Force(IETF)has developed the IPv6 Routing Protocol for Low-power and Lossy Networks(RPL)to address the unique requirements of such networks.Recognizing the critical role of RPL in maintaining high performance,this paper proposes a novel approach to optimizing power consumption.Specifically,it introduces a developed sensor motes topology integrated with a Radio Duty Cycling(RDC)mechanism aimed at minimizing power usage.Through rigorous analysis,the paper evaluates the power efficiency of this approach through several simulations conducted across different network topologies,including random,linear,tree,and elliptical topologies.Additionally,three distinct RDC mechanisms—CXMAC,ContikiMAC,and NullRDC—are investigated to assess their impact on power consumption.The findings of the study,based on a comprehensive and deep analysis of the simulated results,highlight the efficiency of ContikiMAC in power conservation.This research contributes valuable insights into enhancing the energy efficiency of RPL-based IoT networks,ultimately facilitating their widespread deployment and usability in diverse environments.
文摘Background Out-of-hospital patients presenting with atypical chest pain and complete left bundle branch block(LBBB)have to be stratified for the presence of coronary artery disease and the risk of developing heart failure(HF).We investigated the pro-gnostic role of coronary CT-angiography(CTA)and echocardiographic global longitudinal strain(GLS)in those patients in a mid-term follow-up.Methods Out-of-hospital patients with LBBB underwent echocardiography and a 64-slice CT angiography were evaluated ret-rospectively.Development of HF or a cardiovascular death were the events scheduled.Results Seventy-eight patients(32 female;mean age:66.0±10.4 years were enrolled.During a follow-up of 33 months(IQR:17-77),one patient(1.5%)experienced a cardiovascular death,14 patients(17.9%)required urgent outpatient visits due to acute de-compensated HF(12 hospitalizations).Echocardiography showed a slightly reduced left ventricular ejection fraction(LVEF)(50.0%±9.8%)and GLS within the normal range(-16.2%±4.1%).CTA analysis showed coronary stenosis>50%in 28 patients(35.9%).A high Agatston score(>100)was observed in 29.5%.Notably,25 patients(32.1%)were diagnosed with left main coron-ary artery disease and 15 patients(16.7%)underwent revascularization during the follow up.Significant associations were ob-served between events and LVEF(P=0.001),diastolic dysfunction grade≥2(P=0.02),GLS(P<0.001),multiple coronary stenos-is(P=0.04)and Agatston score(P=0.05).Multivariate analysis confirmed the relationships with LVEF(R^(2)=0.89,P<0.001),dia-stolic dysfunction(R^(2)=3.30,P=0.04),GLS(R^(2)=1.43,P<0.001),and Agatston score(R^(2)=1.01,P=0.05).Conclusions In patients with complete LBBB,CTA and GLS identified those at a high risk of development HF.
文摘This study presents a two-echelon inventory routing problem (2E-IRP) with an end-of-tour replenishment (ETR) policy whose distribution network consists of a supplier, several distribution centers (DCs) and several retailers on a multi-period planning horizon. A formulation of the problem based on vehicle indices is proposed in the form of a mixed integer linear program (MILP). The mathematical model of the problem is solved using a branch and cut (B&C) algorithm. The results of the tests are compared to the results of a branch and price (B&P) algorithm from the literature on 2E-IRP with a classical distribution policy. The results of the tests show that the B&C algorithm solves 197 out of 200 instances (98.5%). The comparison of the B&C and B&P results shows that 185 best solutions are obtained with the B&C algorithm on 197 instances (93.9%). Overall, the B&C algorithm achieves cost reductions ranging from 0.26% to 41.44% compared to the classic 2E-IRP results solved with the B&P algorithm, with an overall average reduction of 18.08%.
基金supported by the National Key Research and Development Program of China(2023YFD1202901)the China Agriculture Research System of MOF and MARA(CARS-02-06)the Key Area Research and Development Program of Guangdong Province(2018B020202008).
文摘To improve the amylose content(AC)and resistant starch content(RSC)of maize kernel starch,we employed the CRISPR/Cas9 system to create mutants of starch branching enzyme I(SBEI)and starch branching enzyme IIb(SBEIIb).A frameshift mutation in SBEI(E1,a nucleotide insertion in exon 6)led to plants with higher RSC(1.07%),lower hundred-kernel weight(HKW,24.71±0.14 g),and lower plant height(PH,218.50±9.42 cm)compared to the wild type(WT).Like the WT,E1 kernel starch had irregular,polygonal shapes with sharp edges.A frameshift mutation in SBEIIb(E2,a four-nucleotide deletion in exon 8)led to higher AC(53.48%)and higher RSC(26.93%)than that for the WT.E2 kernel starch was significantly different from the WT regarding granule morphology,chain length distribution pattern,X-ray diffraction pattern,and thermal characteristics;the starch granules were more irregular in shape and comprised typical B-type crystals.Mutating SBEI and SBEIIb(E12)had a synergistic effect on RSC,HKW,PH,starch properties,and starch biosynthesis-associated gene expression.SBEIIa,SS1,SSIIa,SSIIIa,and SSIIIb were upregulated in E12 endosperm compared to WT endosperm.This study lays the foundation for rapidly improving the starch properties of elite maize lines.
文摘Canopy and branch architectures in high-density orchards can be crucial in production and fruit quality. The influence of two canopy orientations (Upright and Tilted) in combination with two arm (branch) architectures (Shortened or Overlapped) on tree growth, yield components, fruit quality, and leaf mineral nutrients in an “Aztec Fuji” apple (Malus domestica Bork.) high-density orchard was studied over five years. Tilted trees with shortened arm configuration (TilShArm) always had significantly larger trunk cross-sectional area (TCSA) than Upright trees with an Overlapped arm configuration (UpOverArm) every year from 2012 to 2016. Trees with a TilShArm system had more cumulative fruit per tree than those with an Upright orientation. Trees with a tilted canopy (TilShArm and TilOverArm) tended to have higher yield per tree and yield per hectare than those with an upright system. Trees with a TilShArm system were more precocious and had more yield per tree than those with an upright canopy orientation in 2012. When values were polled over five years, trees with an upright canopy-shortened arm system (UpShArm) treatment had a lower biennial bearing index (BBI) than those with an upright canopy-overlapped system (UpOverArm). Trees receiving an arm shortening (UpShArm or TilShArm) configuration often had larger fruits than those with overlapped arms (UpOverArm and TilOverArm). Fruit from trees receiving an UpOverArm had higher fruit firmness than those from trees with other canopy-branch arrangements at harvest due to their smaller size. Fruit from trees with a TilShArm and TilOverArm had significantly higher water core and bitter pit but lower sunburn than trees with an upright canopy (UpShArm and UpOverArm). Leaves from trees with an UpOverArm canopy-branch configuration had the lowest leaf Ca but the highest leaf K and Fe concentrations among all treatments.
基金supported by the National Key R&D Program of China(2022YFA1006102).
文摘Let{Z_(n)}_(n)≥0 be a critical or subcritical d-dimensional branching random walk started from a Poisson random measure whose intensity measure is the Lebesugue measure on R^(d).Denote by R_(n):=sup{u>0:Z_(n)({x∈R^(d):∣x∣<u})=0}the radius of the largest empty ball centered at the origin of Z_(n).In this work,we prove that after suitable renormalization,Rn converges in law to some non-degenerate distribution as n→∞.Furthermore,our work shows that the renormalization scales depend on the offspring law and the dimension of the branching random walk.This completes the results of Révész[13]for the critical binary branching Wiener process.
基金supported by the National Natural Science Foundation of China(52276195)Program for Supporting Innovative Research from Jinan(202228072)Program of Agricultural Development from Shandong(SD2019NJ015)。
文摘Development of pore structures of activated carbon(AC)from activation of biomass with ZnCl_(2) relies on content and structure of cellulose/hemicellulose in the feedstock.Thermal pretreatment of biomass could induce dehydration and/or aromatization to change the structure of cellulose/hemicellulose.This might interfere with evolution of structures of AC,which was investigated herein via thermal pretreatment of willow branch(WB)from 200 to 360℃and the subsequent activation with ZnCl_(2) at 550℃.The results showed that thermal pretreatment at 360℃(WB-360)could lead to substantial pyrolysis to form biochar,with a yield of 31.9%,accompanying with nearly complete destruction of cellulose crystals and remarkably enhanced aromatic degree.However,cellulose residual in WB-360 could still be activated to form AC-360 with specific surface area of 1837.9 m~2·g^(-1),which was lower than that in AC from activation of untreated WB(AC-blank,2077.8 m~2·g^(-1)).Nonetheless,the AC-200 from activation of WB-200 had more developed pores(2113.9 m~2·g^(-1))and superior capability for adsorption of phenol,due to increased permeability of ZnCl_(2) to the largely intact cellulose structure in WB-200.The thermal pretreatment did increase diameters of micropores of AC but reduced the overall yield of AC(26.8%for AC-blank versus 18.0%for AC-360),resulting from accelerated cracking but reduced intensity of condensation.In-situ infrared characterization of the activation showed that ZnCl_(2) mainly catalyzed dehydration,dehydrogenation,condensation,and aromatization but not cracking,suppressing the formation of derivatives of cellulose and lignin in bio-oil.The thermal pretreatment formed phenolic-OH and C=O with higher chemical innerness,which changed the reaction network in activation,shifting morphology of fibrous structures in AC-blank to“melting surface”in AC-200 or AC-280.
基金co-supported by the National Natural Science Foundation Project (No.40872137,40372103)Crisis Mines Study Project (No.20089948)Inner Mongolia Geological Exploring Important Project (No.2004-05)
文摘Mantle branch structure is the third tectonic unit of multiple evolution of a mantle branch. It is not only the main mechanism of intercontinental orogeny, but also an important ore-forming and ore-control structure. Studies on geotectonic evolution, regional geological characteristics and oreforming and ore-control structures have shown that since the Mesozoic the Da Hinggan Mts. region has entered a typical intercontinental orogenic stage, and it is closely related to mantle branch activities. The south-central segment of the Da Hinggan Mts. is a typical mantle branch structure and possesses obvious magmatic-metamorphic complexes in the core, detachment slip beds in the periphery and overlapped fault depression basins. Moreover, all of these are the principal factors leading to ore formation and ore control in the region. This paper also further explores the mechanism of mineralization in the south-central segment of the Da Hinggan, summaries the rules of mineralization, puts forward the models of mineralization and points out future ore-exploring orientation.
基金The National Key Research and Development Program of China under contract Nos 2016YFC1401403,2016YFB0201103 and 2017YFA0604101the Strategic Priority Research Program of Chinese Academy of Sciences under contract No.XDA11020301+1 种基金the National Natural Science Foundation of China under contract No.41206025the China Ocean Mineral Resources R&D Association Program under contract No.DY135-E2-1-06
文摘Using observational data of Argos satellite-tracked drifters from 1988 to 2012, we analyzed seasonal characteristics of the surface Kuroshio branch(KB) intrusion into the South China Sea(SCS). The analysis results are as follows.The surface KB originates from the southern Balintang Channel(BLTC) and Babuyan Channel(BBYC). It begins in late September, reaches peak strength in November–December, and declines at the end of March. The mean speed of drifters along the KB path during their traverse of the Luzon Strait(LS) was 43% faster than during the two days before entering the LS for the flow originating from the southern BLTC, but there was a 24% increase in speed for the flow from the BBYC. The observations show that in winter, monthly-mean sea-level anomalies(SLAs) were positive southwest of Taiwan Island and extended to the northern LS. The SLAs were negative northwest of Luzon Island and extended to the southern LS, which acted like a pump, forcing a part of Kuroshio water westward into the SCS. The condition under which the KB forms was solved by a set of simplified motion equations. The results indicate that whether the KB can form depends upon the sea-level gradient at the central LS and region to the west, as well as the location, speed and direction of Kuroshio surface water when it enters the LS.
基金financially supported by the National Natural Science Foundation of China(grants No.41602105,41530966,41672106 and 41472086)China Postdoctoral Science Foundation(grant No.2016M590655)the fundamental Research Funds for the Central Universities,Ocean University of China
文摘Objective The eastern extending range of the Paleo-Tethys Ocean in southwest China has always been focused and controversial. At the beginning of this century some scholars proposed that the Paleo-Tethys Branch Ocean may extend to the Babu-Pingxiang and Cengxi areas along the stouthwestern margin of the South China Block (Cai and Zhang, 2009). However, the pivotal proof of Late Paleozoic ophoilite and magmatic rocks was absent or sporadical in the Guangxi Zhuang Autonomous Region, resulting in insufficient evidence to support this viewpoint. For the first time this work reported the Late Devonian tuff in the Qinzhou area in the south of the Guangxi Zhuang Autonomous Region and conducted zircon U-Pb dating on it in order to constrain the extension of the Paleo-Tethys Ocean in the South China Block.
文摘AIM:To identify factors contributing to visual improvement after treatment of macular edema(ME)secondary to branch retinal vein occlusion(BRVO),and to assess the interaction between laser therapy and intravitreal ranibizumab(IVR).METHODS:We retrospectively reviewed the medical records of patients who had been treated for BRVO-related ME at our hospital.Records were traceable for at least 12 mo,and evaluated factors included age,sex,medical history,smoking history,treatment methods,foveal hemorrhage,and change in visual acuity.Treatments included laser therapy,IVR,sub-Tenon’s capsule injection of triamcinolone(STTA),a combination,or no intervention.Multivariate logistic regression analysis and interaction terms were used to assess the clinical efficacy of the treatments,and odds ratios(OR)and 95%confidence intervals(CI)were calculated.RESULTS:Seventy-three patients(34 men,39 women;73 eyes)with a mean age of 69.4±12.1 y were included.Patients who underwent IVR monotherapy,laser monotherapy,and STTA+laser had significantly higher best corrected visual acuity at 12 mo compared to baseline(P<0.001,<0.001,and 0.019,respectively).Logistic regression analysis without interaction terms found that IVR was a significant visual acuity recovery factor(adjusted OR:3.89,95%CI:1.25-12.1,P=0.019).Adjusted OR using an interaction model by logistic regression was 16.6(95%CI:2.54-108.47,P=0.003)with IVR treatment,and 8.25(95%CI:1.34-50.57,P=0.023)with laser treatment.No interaction was observed(adjusted OR:0.07,95%CI:0.01-0.75,P=0.029).CONCLUSION:IVR contributes to improvements in visual acuity at 12 mo in ME secondary to BRVO.No interaction is observed between laser therapy and IVR treatments.
基金Sleep Center,Department of Otolaryngology,Phramongkutklao Hospital
文摘Background: It is crucial for the army to know the prevalence of obstructive sleep apnea(OSA) syndrome in activeduty army personnel. Little information has been reported on the prevalence of OSA and clinical features in activeduty army personnel. This study was aimed to estimate the prevalence of snoring and risk of developing OSA in activeduty army personnel in Thailand and to identify the co-morbidities of OSA. In total, 1107 participants who were aged20–60 years and were deployed to the three southernmost provinces of Thailand were enrolled. All the participants completed the Phramongkutklao(PMK) Hospital OSA Questionnaire that was modified and validated from the Berlin Questionnaire and underwent physical examination. The participants were 1107 active-duty army personnel in the three southernmost provinces of Thailand, both males and females, aged 20–60 years.Methods: The PMK OSA Questionnaire was used to assess the risk of OSA together with interviewing for snoring,fatigue, falling asleep and day-time sleepiness. Physical examination of the neck, chest and hip circumference,and height was performed. Information concerning physical training, co-morbid diseases, smoking and alcoholic consumption was collected.Results: The prevalence of snoring was 58.5, and 4.8% met the PMK OSA Questionnaire criteria, thus indicating a high risk of OSA. The information obtained indicated that laryngopharyngeal reflux(LPR), current smoking and alcoholic consumption were significantly higher in the high-risk OSA group.Conclusions: Early detection and treatment of OSA in active-duty army personnel are imperative. Physical examination and polysomnography can be used to reveal the high-risk group. High body mess index(BMI), laryngopharyngeal reflux, current smoking and alcoholic consumption are modifiable factors for OSA and are avoidable. A policy to decrease the BMI and risk of LPR, as well as to stop smoking and alcoholic consumption, should be applied.
文摘The general form of the north-branch of the Changjiang River mouth has changed much as a result of the change of the main stream lines of the Nantong reach of the Changjiang River and the influence of human activities since 1915. By the 1930s, the main stream lines of the Nantong reach of the Changjiang River has shifted to the Tongzhou Bar west channel. The north-branch at the Changjiang River mouth has become atrophic because of Tongzhou Bar east channel's deposition. After 1958, Toughal Bar and Jiangxin Bar were exploited. And in 1970, the north channel of Jiangxin Bar was blocked up. All these things make the water of the north-branch more difficult to pass through. It leads to the decline of the total discharge percentage of the north-branch. And it causes the rising tide to go back to the south-branch. However, since 1978, with the development of Tongzhou Bar east channel and its left bank being scoured, the water amount of the north-branch has been increasing. And the water,load and salt of going back to the south-branch has been becoming less.
文摘The Fifteenth Natlonal Con-gress,a very important andgrand trans—century meeting inthe history Of CCP,was inaugu-rated in Beijing on September 12,1997. Guangdong Customs have sentrepresentatives to attend the Party’sCongress for the first time in his-tory.Among the two representa-tives is Liu Wenjie,director ofGuangdong CUStoms Branch Of-fice and of Guangzhou Customs.On September 23 after conclusionof the Coilgress,this reporter inte-Viewed directory Liu Wenjie in
基金This paper was a part of the National Key Project of Science and Technology on Masson Pine breeding during 1996-2000.
文摘The features of branching and growth studied included height, diameter at breast height (DBH), total number of branches, annual height growth, annual branch elongation in the year of elongating, annual branch number for four consecutive years, diameter of branches of different ages, and diameter of stem where branch-whorl originates. For features of total growth and overall branching, no significant differences were found between families, except for DBH. For annual features, no significant differences were found in annual stem height growth, annual branch elongation in the year of elongation and diameter of branches. In the last four years, differences in number of branches were not significant in the first two years but were significant in the last two year; differences in stem diameter where branch-whorls grow were significant for the four consecutive years. Trend of annual growth and branching features of families can be divided into three types as increasing type, stable type and fluctuating type. Most of families have an increasing type with respect of annual height growth and annual branch elongation, while most families belong to a fluctuating type with annual branch number. The results indicated that in the fifth year after planted in seedling seed orchard, differences between families were mostly insignificant. This result may have two main explanations: one is the growth rhyme in early ages of Masson pine, the other one is the complex paternal components to form the open-pollinated families. Family selection seemed to be not useful based on the result. It is suggested to select some of families in the nursery instead of to use all the families when establishing seedling seed orchards with open-pollinated families from plus-trees.
基金Supported by National Department Public Benefit Research Foundation(201304701-4)Science and Technology Planning Program of Xinjiang Uygur Autonomous RegionXinjiang Uygur Autonomous Region Fruit Major Subjects~~
文摘ObjectiveThe thesis aims at investigating the distribution and structural characteristics of various branches in canopy of Korla fragrant pear. MethodStatistic work and analysis were conducted on the numbers and distribution characteristics of various branches in each cubic lattice by using the canopy cellular method. ResultThe results showed that: The total number of scaffold branches of evacuation layered tree shape was 97, which mainly distributed in the lower layer and middle part of the canopy; the total number of scaffold branches of open-center tree shape was 94, which mainly distributed in the lower layer and middle part of the canopy. The total number of annual branches of evacuation layered tree shape was 3 920, which mainly distributed in the middle layer and outer part of the canopy; and the total number of annual branches of the open-center tree shape was 3 183, which mainly distributed in middle layer and outer part of the canopy. The total number of perennial branches of evacuation layered tree shape was 2 184, which mainly distributed in lower layer and outer part of the canopy; the total number of perennial branches of open-center tree shape was 1 444, which mainly distributed in middle layer and outer part of the canopy. ConclusionThe total number and the distribution positions of scaffold branches in the canopy of each tree shape were basically the same. The total numbers of annual branches of the two kinds of tree shapes were different, but the distribution positions were basically the same. The total numbers and the distribution positions of perennial branches in the canopy of the two kinds of tree shapes were different.
文摘Based on the natural resources in Ganzi Tibetan Autonomous Prefecture, screening experiment of strains and nutrient sources for culture of Armillariella mellea rhizomoph branch was carried out with 3 strains of A. mellea, 2 types of main nutrient sources and 3 kinds of auxiliary nutrient sources. Total 18 treatments were designed. The results showed that with the A. mellea strain separated from the tubers of wild Gastrodia elata BI. by tissue isolation as mother strain, the shrubs such as Prunus tatsienensis Batal and Quercus spinosa David ex Franch as the main nutrient sources, and the agricultural products such as corn and potato as the supplementary nutrient sources, the growth of A. mellea rhizomoph branch was best in bottle.
基金Supported by National Center of Transgenic Plant Research and Commercialization Special Fund(J99-13-001)Jilin Agricultural Science & Technology College Fund~~
文摘[Objective] The aim was to construct promoter of maize starch-branching enzyme sbe Ⅱb gene specifically expressed in seed.[Method] The promoter sequence of maize starch-branching enzyme sbe Ⅱb gene was amplified by LA-PCR and then cloned into pMD18-T vector.Subsequently,the promoter was cloned into pBI121 vector to construct plant expression vector pBI121-sbe Ⅱb.Recombinant plasmid pSBE-GUS was constructed by connecting GUS gene into pBI121-sbe Ⅱb and transformed into tobacco mediated by Agrobacterium tumefaciens,before detection by PCR and Southern blot.The biochemical analysis and fluorescence detection of GUS activity were performed in different parts of the tobacco by Gene Gun Method and Agrobacterium tumefaciens transformation respectively.[Result] The homology between promoter sequence cloned in this experiment and the corresponding sequence announced in the GenBank reached 98.52%.Four transformed tobaccos were obtained by PCR and Southern blot after co-culture and selective culture.A small number of blue spots appeared in leaves,and the spots could barely been seen in the stems and roots,while a large number of blue spots were found in seeds.So,it could be concluded that the promoter of sbeⅡb gene was specifically expressed in seeds.[Conclusion] Promoter of maize starch branching enzyme sbe Ⅱb specifically expressed in seeds was successfully cloned.
文摘A parameter estimation algorithm of the continuous hidden Markov model isintroduced and the rigorous proof of its convergence is also included. The algorithm uses theViterbi algorithm instead of K-means clustering used in the segmental K-means algorithm to determineoptimal state and branch sequences. Based on the optimal sequence, parameters are estimated withmaximum-likelihood as objective functions. Comparisons with the traditional Baum-Welch and segmentalK-means algorithms on various aspects, such as optimal objectives and fundamentals, are made. Allthree algorithms are applied to face recognition. Results indicate that the proposed algorithm canreduce training time with comparable recognition rate and it is least sensitive to the training set.So its average performance exceeds the other two.
文摘BACKGROUND Left bundle branch pacing(LBBP)is a novel pacing modality of cardiac resynchronization therapy(CRT)that achieves more physiologic native ventricular activation than biventricular pacing(BiVP).AIM To explore the validity of electromechanical resynchronization,clinical and echocardiographic response of LBBP-CRT.METHODS Systematic review and Meta-analysis were conducted in accordance with the standard guidelines as mentioned in detail in the methodology section.RESULTS In our analysis,the success rate of LBBP-CRT was determined to be 91.1%.LBBP CRT significantly shortened QRS duration,with significant improvement in echocardiographic parameters,including left ventricular ejection fraction,left ventricular end-diastolic diameter and left ventricular end-systolic diameter in comparison with BiVP-CRT.CONCLUSION A significant reduction in New York Heart Association class and B-type natriuretic peptide levels was also observed in the LBBP-CRT group vs BiVP-CRT group.Lastly,the LBBP-CRT cohort had a reduced pacing threshold at follow-up as compared to BiVP-CRT.