Due to the mismatch of the circuit oscillators,there will always be a frequency offset between the transmitter and the receiver.In the adjacent channel interference(ACI)suppression system using the reconstruction and ...Due to the mismatch of the circuit oscillators,there will always be a frequency offset between the transmitter and the receiver.In the adjacent channel interference(ACI)suppression system using the reconstruction and cancellation method,the frequency offset decreases the accuracy of the reconstructed signal and introduces a time-varying term in the interference cancellation,resulting in poor performance of the ACI suppression.In this paper,the relationship between the normalized frequency offset,signal-to-noise ratio and the loss of interference suppression capability is analyzed through formula derivation and simulation.The validity of the frequency offset compensation method based on the pilot sequence is verified,and the relationship between the sequence length and the estimation accuracy is given.This paper provides necessary method reference and data support for the engineering of ACI suppression.展开更多
Passive detection of low-slow-small(LSS)targets is easily interfered by direct signal and multipath clutter,and the traditional clutter suppression method has the contradiction between step size and convergence rate.I...Passive detection of low-slow-small(LSS)targets is easily interfered by direct signal and multipath clutter,and the traditional clutter suppression method has the contradiction between step size and convergence rate.In this paper,a frequency domain clutter suppression algorithm based on sparse adaptive filtering is proposed.The pulse compression operation between the error signal and the input reference signal is added to the cost function as a sparsity constraint,and the criterion for filter weight updating is improved to obtain a purer echo signal.At the same time,the step size and penalty factor are brought into the adaptive iteration process,and the input data is used to drive the adaptive changes of parameters such as step size.The proposed algorithm has a small amount of calculation,which improves the robustness to parameters such as step size,reduces the weight error of the filter and has a good clutter suppression performance.展开更多
The influence of frequency modulation (FM) interfer- ence on correlation detection performance of the pseudo random code continuous wave (PRC-CW) radar is analyzed. It is found that the correlation output deterior...The influence of frequency modulation (FM) interfer- ence on correlation detection performance of the pseudo random code continuous wave (PRC-CW) radar is analyzed. It is found that the correlation output deteriorates greatly when the FM inter- ference power exceeds the anti-jamming limit of the radar. Accord- ing to the fact that the PRC-CW radar echo is a wideband pseudo random signal occupying the whole TF plane, while the FM in- terference only concentrates in a small portion, a new method is proposed based on adaptive short-time Fourier transform (STFT) and time-varying filtering for FM interference suppression. This method filters the received signal by using a binary mask to excise only the portion of the TF plane corrupted by the interference. Two types of interference, linear FM (LFM) and sinusoidal FM (SFM), under different signal-to-jamming ratio (S JR) are studied. It is shown that the proposed method can effectively suppress the FM interference and improve the performance of target detection.展开更多
The adaptive digital beamforming technique in the space-polarization domain suppresses the interference with forming the coupling nulls of space and polarization domain.When there is the interference in mainlobe,it wi...The adaptive digital beamforming technique in the space-polarization domain suppresses the interference with forming the coupling nulls of space and polarization domain.When there is the interference in mainlobe,it will cause serious mainlobe distortion,that the target detection suffers from.To overcome this problem and make radar cope with the complex multiple interferences scenarios,we propose a multiple mainlobe and/or sidelobe interferences suppression method for dual polarization array radar.Specifically,the proposed method consists of a signal preprocessing based on the proposed angle estimation with degree of polarization(DoP),and a filtering criterion based on the proposed linear constraint.The signal preprocessing provides the accurate estimated parameters of the interference,which contributes to the criterion for null-decoupling in the space-polarization domain of mainlobe.The proposed method can reduce the mainlobe distortion in the space-polarization domain while suppressing the multiple mainlobe and/or sidelobe interferences.The effectiveness of the proposed method is verified by simulations.展开更多
Interference suppression is a challenge for radar researchers, especially when mainlobe and sidelobe interference coexist. We present a comprehensive anti-interference approach based on a cognitive bistatic airborne r...Interference suppression is a challenge for radar researchers, especially when mainlobe and sidelobe interference coexist. We present a comprehensive anti-interference approach based on a cognitive bistatic airborne radar. The risk of interception is reduced by lowering the launch energy of the radar transmitting terminal in the direction of interference;main lobe and sidelobe interferences are suppressed via cooperation between the two radars. The interference received by a single radar is extracted from the overall radar signal using multiple signal classification(MUSIC), and the interference is cross-located using two different azimuthal angles. Neural networks allowing good, non-linear nonparametric approximations are used to predict the location of interference, and this information is then used to preset the transmitting notch antenna to reduce the likelihood of interception. To simultaneously suppress mainlobe and sidelobe interferences, a blocking matrix is used to mask mainlobe interference based on azimuthal information, and an adaptive process is used to suppress sidelobe interference. Mainlobe interference is eliminated using the data received by the two radars. Simulation verifies the performance of the model.展开更多
This paper presents an improved error function of dithered signed-error constant modulus algorithm (IDSE-CMA) for blind multiuser interference suppression in DS/CDMA systems. It uses a different error function to re...This paper presents an improved error function of dithered signed-error constant modulus algorithm (IDSE-CMA) for blind multiuser interference suppression in DS/CDMA systems. It uses a different error function to replace the former one in sign operation of the DSE-CMA and compares their performance in multiple access interference (MAI) suppression ability. Simulations indicate that the new algorithm has better performance than the similar CMA in terms of convergence speed and steady-state performance:展开更多
In this paper, we propose a new technique to effectively suppress non-stationary interference signal for wireless networks. This technique combines a new scheme of interference signal estimation with the intelligent o...In this paper, we propose a new technique to effectively suppress non-stationary interference signal for wireless networks. This technique combines a new scheme of interference signal estimation with the intelligent optimization projection. In order to capture interference signal's subspace, a time-varying method is used to estimate the non-stationary interference.Orthogonal polynomials are used for the basis function instead of the power of the time to reduce the computational complexity.The interference is then removed from the corrupted signal by subspace projection, resulting in less distortion to the desired signal. The performance of this approach is validated by computer simulation.展开更多
Subset Parallel Adaptive Volterra Filter (SPAVF) design algorithm is proposed in this letter. Contri-bution factor is introduced in SPAVF, and it can get rid of redundant elements efficiently in the extended input vec...Subset Parallel Adaptive Volterra Filter (SPAVF) design algorithm is proposed in this letter. Contri-bution factor is introduced in SPAVF, and it can get rid of redundant elements efficiently in the extended input vector. Computational weight can be reduced largely, and BER performance of SPAVF can be improved by getting rid of the influence of redundant elements in the input vector. Simulation result proves its advantage compared to AVF and PSVF.展开更多
The negative impact on communication performance in wireless multi-hop communication net-work caused by limited bandwidth,high bit eror rate (BER),fading,noise and interference is alleviated by an adaptive filtering...The negative impact on communication performance in wireless multi-hop communication net-work caused by limited bandwidth,high bit eror rate (BER),fading,noise and interference is alleviated by an adaptive filtering game based on frequency subbands selection and predetemined threshold.Such threshold is being obtained in Gaussian and multipath fading channel according to the frequency-matching principle and BER performance.The dynamic selection of subbands will obtain high use efficiency without the help of frequency hopping,and propound a new thought to improve band limited communication for wireless multi-hop communication network.The effectiveness of the adaptive filtering method has been verified by interleaving spread spectrum orthogonal frequency division multiplexing (ISS-OFDM) in different interference conditions,and the simulating results based on network simulator 2 (NS2) indicate that system BER can be improved greatly.展开更多
A new cross-channel interference suppression method is proposed to decrease the cross-channel interference in beat signals based on the short time Fourier transform (STY3") and the inverse short time Fourier transf...A new cross-channel interference suppression method is proposed to decrease the cross-channel interference in beat signals based on the short time Fourier transform (STY3") and the inverse short time Fourier transform (ISTFT) when the dual-orthogonal polarimetric frequency-modulated continu- ous wave (FMCW) radar adopts the opposite-slope linear frequency modulation signal pair in the simultaneous measurement mode. The STFT is applied only on the signals in the cross-interference intervals in the four polarimetric channels to decrease the computation complexity. A mask matrix for suppressing the interference is constructed using the constant false alarm ratio (CFAR) detection on the spectrograms by the STFY. The simulative results show that the cross-channel interference is effi- ciently suppressed by the proposed method. The comparison between the proposed method and the rejection method verifies the improved performance of the proposed method.展开更多
The key to narrow-band interference excision in frequency domain is to determine the excision thresh- old in direct-sequence spread-spectrum (DS-SS) systems. The excision threshold is a non-linear function related t...The key to narrow-band interference excision in frequency domain is to determine the excision thresh- old in direct-sequence spread-spectrum (DS-SS) systems. The excision threshold is a non-linear function related to the number and the power of interference, and attempting to get the exact relation of threshold related to the number and the power of interference is almost impossible. The N-sigma algorithm determines the excision threshold using subsection function; however, the excision threshold determined by this method is not exact. A new method to determine the threshold of N-sigma algorithm is proposed. The new method modifies the scale factor N by use of the membership function. The threshold determined by this method is consecutive and smooth, and it is closer to the fact than that of the initial N-sigma algorithm. The GPS signal and single-tone (CW) interference (that is, typical narrow-band interference) are implemented in the simulation, and the results are presented to demonstrate the validity of the new algorithm.展开更多
To overcome the inter-carrier interference (ICI) of orthogonal frequency division multiplexing (OFDM) systems subject to unknown carrier frequency offset (CFO) and multipath, this paper develops a blind adaptive...To overcome the inter-carrier interference (ICI) of orthogonal frequency division multiplexing (OFDM) systems subject to unknown carrier frequency offset (CFO) and multipath, this paper develops a blind adaptive interference suppression scheme based on independent component analysis (ICA). Taking into account statistical independence of subcarriers' signals of OFDM, the signal recovery mechanism is investigated to achieve the goal of blind equalization. The received OFDM signals can be considered as the mixed observation signals. The effect of CFO and multipath corresponds to the mixing matrix in the problem of blind source separation (BSS) framework. In this paper, the ICA- based OFDM system model is built, and the proposed ICA-based detector is exploited to extract source signals from the observation of a received mixture based on the assumption of statistical independence between the sources. The blind separation technique can increase spectral efficiency and provide robustness performance against erroneous parameter estimation problem. Theoretical analysis and simulation results show that compared with the conventional pilot-based scheme, the improved performance of OFDM systems is obtained by the proposed ICA-based detection technique.展开更多
Radio Frequency Interference (RFI) degrades the quality of focused Ultra-WideBand Syn- thetic Aperture Radar (UWB SAR) images. From both the theoretical analysis and real data valida- tion, it is concluded that target...Radio Frequency Interference (RFI) degrades the quality of focused Ultra-WideBand Syn- thetic Aperture Radar (UWB SAR) images. From both the theoretical analysis and real data valida- tion, it is concluded that target echo and RFI have different Region Of Support (ROS) in 2-D fast- time wavenumber and aperture wavenumber domain. Consequently, a novel adaptive filter is pro- posed according to the Wiener optimum criterion on the distinct ROS characteristics of target echo and RFI. Compared with the notch filter and the Least Mean Square (LMS) adaptive filter in previ- ous literatures, the proposed method is more computationally efficient with satisfactory suppression results. In terms of Signal-to-Interference Ratio Improvement (SIRI) and processing time, the per- formance of the proposed adaptive filter is verified with the field data collected with a UWB SAR system.展开更多
A new method of single sample polarization filtering is proposed. The algorithm is fast and suitable for the polarization processing of stationary or nonstationary polarized disturbed signals with one or more independ...A new method of single sample polarization filtering is proposed. The algorithm is fast and suitable for the polarization processing of stationary or nonstationary polarized disturbed signals with one or more independent disturbances. A ground wave polarimetric radar with the ability of radio disturbance suppression is then introduced. Some numerical results demonstrate the effectiveness of single sample polarization filtering method for ground wave polarimetric radar.展开更多
The 3-D beamforming scheme has elite as evolving interest because of its efficiency to empower assorted techniques such as vertical and horizontal domains and emanation beamforming according to subscriber's provis...The 3-D beamforming scheme has elite as evolving interest because of its efficiency to empower assorted techniques such as vertical and horizontal domains and emanation beamforming according to subscriber's provisions. Usually, 3-D beamforming communication is set up on FDD/TDD approach those effects on the performance of spectrum and energy efficiency. Co-frequency and CoTime Full Duplex(CCFD) is an effective solution to improve the spectrum and energy efficiency by transmitting and receiving simultaneously in frequency and time domain. While, CCFD communication often face the self-interference issue when communication occurs, simultaneously. Consequently, in this paper a self-interference elimination by physical feedback channel in CCFD for 3-D Beamforming communication scheme is proposed to improve the over-all system performance in terms of energy and spectrum efficiency. The simulation and analytical outcomes demonstrated that the proposed system is superior than the traditional one.展开更多
Objective: To explore the inhibition of the expression of c-Myc in human hepatocellular carcinoma via vector-based RNA interference (RNAi). Methods: Two RNA interference DNA templates targeting c-Myc oncogene were des...Objective: To explore the inhibition of the expression of c-Myc in human hepatocellular carcinoma via vector-based RNA interference (RNAi). Methods: Two RNA interference DNA templates targeting c-Myc oncogene were designed via online software and synthesized. By ligation, the fragments were inserted into pSilencer 1.0-U6 to construct the recombinant siRNA expressing plasmids. The identified recombinants were introduced into BEL-7402 cells with Lipofactamine. The inhibition of c-Myc expression, together with the expression of CDK4, hTERT and Gadd45β in c-Myc down-regulated BEL-7402 cells, were analyzed by semi-quantitative RT-PCR. Results: Two recombinant plasmids pSic-myc-1 and pSic-myc-2, which direct the yields of siRNAs targeting c-Myc in cells, were constructed. Among which, pSic-myc-2 was shown to trigger a RNAi-mediated inhibition of expression of c-Myc in BEL-7402 by up to 90%. In c-Myc knockdown BEL-7402 cells, the expression of CDK4 and hTERT were down-regulated with a ratio of 85% and 57%, respectively, while the expression of Gadd45β was up-regulated by up to 110%. Conclusion: The expression of c-Myc in BEL-7402 could be suppressed by vector-based RNA interference successfully. The knockdown of c-Myc in turn resulted in the changes of expression of genes related to cell proliferation and apoptosis. Thus, our study provided a preliminary data in searching of a c-Myc-targeted RNAi therapy of human hepatocellular carcinoma.展开更多
基金supported by the National Key R&D Program of China under grant 2018YFB1801903the National Natural Science Foundation of China under grants U19B2014,61771107,62071094,61701075,61601064,and 61531009。
文摘Due to the mismatch of the circuit oscillators,there will always be a frequency offset between the transmitter and the receiver.In the adjacent channel interference(ACI)suppression system using the reconstruction and cancellation method,the frequency offset decreases the accuracy of the reconstructed signal and introduces a time-varying term in the interference cancellation,resulting in poor performance of the ACI suppression.In this paper,the relationship between the normalized frequency offset,signal-to-noise ratio and the loss of interference suppression capability is analyzed through formula derivation and simulation.The validity of the frequency offset compensation method based on the pilot sequence is verified,and the relationship between the sequence length and the estimation accuracy is given.This paper provides necessary method reference and data support for the engineering of ACI suppression.
文摘Passive detection of low-slow-small(LSS)targets is easily interfered by direct signal and multipath clutter,and the traditional clutter suppression method has the contradiction between step size and convergence rate.In this paper,a frequency domain clutter suppression algorithm based on sparse adaptive filtering is proposed.The pulse compression operation between the error signal and the input reference signal is added to the cost function as a sparsity constraint,and the criterion for filter weight updating is improved to obtain a purer echo signal.At the same time,the step size and penalty factor are brought into the adaptive iteration process,and the input data is used to drive the adaptive changes of parameters such as step size.The proposed algorithm has a small amount of calculation,which improves the robustness to parameters such as step size,reduces the weight error of the filter and has a good clutter suppression performance.
文摘The influence of frequency modulation (FM) interfer- ence on correlation detection performance of the pseudo random code continuous wave (PRC-CW) radar is analyzed. It is found that the correlation output deteriorates greatly when the FM inter- ference power exceeds the anti-jamming limit of the radar. Accord- ing to the fact that the PRC-CW radar echo is a wideband pseudo random signal occupying the whole TF plane, while the FM in- terference only concentrates in a small portion, a new method is proposed based on adaptive short-time Fourier transform (STFT) and time-varying filtering for FM interference suppression. This method filters the received signal by using a binary mask to excise only the portion of the TF plane corrupted by the interference. Two types of interference, linear FM (LFM) and sinusoidal FM (SFM), under different signal-to-jamming ratio (S JR) are studied. It is shown that the proposed method can effectively suppress the FM interference and improve the performance of target detection.
基金supported by the National Natural Science Foundation of China(6190149661871385)。
文摘The adaptive digital beamforming technique in the space-polarization domain suppresses the interference with forming the coupling nulls of space and polarization domain.When there is the interference in mainlobe,it will cause serious mainlobe distortion,that the target detection suffers from.To overcome this problem and make radar cope with the complex multiple interferences scenarios,we propose a multiple mainlobe and/or sidelobe interferences suppression method for dual polarization array radar.Specifically,the proposed method consists of a signal preprocessing based on the proposed angle estimation with degree of polarization(DoP),and a filtering criterion based on the proposed linear constraint.The signal preprocessing provides the accurate estimated parameters of the interference,which contributes to the criterion for null-decoupling in the space-polarization domain of mainlobe.The proposed method can reduce the mainlobe distortion in the space-polarization domain while suppressing the multiple mainlobe and/or sidelobe interferences.The effectiveness of the proposed method is verified by simulations.
文摘Interference suppression is a challenge for radar researchers, especially when mainlobe and sidelobe interference coexist. We present a comprehensive anti-interference approach based on a cognitive bistatic airborne radar. The risk of interception is reduced by lowering the launch energy of the radar transmitting terminal in the direction of interference;main lobe and sidelobe interferences are suppressed via cooperation between the two radars. The interference received by a single radar is extracted from the overall radar signal using multiple signal classification(MUSIC), and the interference is cross-located using two different azimuthal angles. Neural networks allowing good, non-linear nonparametric approximations are used to predict the location of interference, and this information is then used to preset the transmitting notch antenna to reduce the likelihood of interception. To simultaneously suppress mainlobe and sidelobe interferences, a blocking matrix is used to mask mainlobe interference based on azimuthal information, and an adaptive process is used to suppress sidelobe interference. Mainlobe interference is eliminated using the data received by the two radars. Simulation verifies the performance of the model.
基金Project supported by National Natural Science Foundation of Chi-na(Grant No .60172018)
文摘This paper presents an improved error function of dithered signed-error constant modulus algorithm (IDSE-CMA) for blind multiuser interference suppression in DS/CDMA systems. It uses a different error function to replace the former one in sign operation of the DSE-CMA and compares their performance in multiple access interference (MAI) suppression ability. Simulations indicate that the new algorithm has better performance than the similar CMA in terms of convergence speed and steady-state performance:
文摘In this paper, we propose a new technique to effectively suppress non-stationary interference signal for wireless networks. This technique combines a new scheme of interference signal estimation with the intelligent optimization projection. In order to capture interference signal's subspace, a time-varying method is used to estimate the non-stationary interference.Orthogonal polynomials are used for the basis function instead of the power of the time to reduce the computational complexity.The interference is then removed from the corrupted signal by subspace projection, resulting in less distortion to the desired signal. The performance of this approach is validated by computer simulation.
文摘Subset Parallel Adaptive Volterra Filter (SPAVF) design algorithm is proposed in this letter. Contri-bution factor is introduced in SPAVF, and it can get rid of redundant elements efficiently in the extended input vector. Computational weight can be reduced largely, and BER performance of SPAVF can be improved by getting rid of the influence of redundant elements in the input vector. Simulation result proves its advantage compared to AVF and PSVF.
基金Supported by the National Nature Science Foundation of China(No.61302074)the Specialized Research Fund for the Doctoral Program of Higher Education(No.20122301120004)+1 种基金the Natural Science Foundation of Heilongjiang Province(No.QC2013C061)Research Foundation of Education Bureau of Heilongjiang Province(No.12531480)
文摘The negative impact on communication performance in wireless multi-hop communication net-work caused by limited bandwidth,high bit eror rate (BER),fading,noise and interference is alleviated by an adaptive filtering game based on frequency subbands selection and predetemined threshold.Such threshold is being obtained in Gaussian and multipath fading channel according to the frequency-matching principle and BER performance.The dynamic selection of subbands will obtain high use efficiency without the help of frequency hopping,and propound a new thought to improve band limited communication for wireless multi-hop communication network.The effectiveness of the adaptive filtering method has been verified by interleaving spread spectrum orthogonal frequency division multiplexing (ISS-OFDM) in different interference conditions,and the simulating results based on network simulator 2 (NS2) indicate that system BER can be improved greatly.
基金Supported by the National Natural Science Foundation of China for Youth(No.41301397)
文摘A new cross-channel interference suppression method is proposed to decrease the cross-channel interference in beat signals based on the short time Fourier transform (STY3") and the inverse short time Fourier transform (ISTFT) when the dual-orthogonal polarimetric frequency-modulated continu- ous wave (FMCW) radar adopts the opposite-slope linear frequency modulation signal pair in the simultaneous measurement mode. The STFT is applied only on the signals in the cross-interference intervals in the four polarimetric channels to decrease the computation complexity. A mask matrix for suppressing the interference is constructed using the constant false alarm ratio (CFAR) detection on the spectrograms by the STFY. The simulative results show that the cross-channel interference is effi- ciently suppressed by the proposed method. The comparison between the proposed method and the rejection method verifies the improved performance of the proposed method.
文摘The key to narrow-band interference excision in frequency domain is to determine the excision thresh- old in direct-sequence spread-spectrum (DS-SS) systems. The excision threshold is a non-linear function related to the number and the power of interference, and attempting to get the exact relation of threshold related to the number and the power of interference is almost impossible. The N-sigma algorithm determines the excision threshold using subsection function; however, the excision threshold determined by this method is not exact. A new method to determine the threshold of N-sigma algorithm is proposed. The new method modifies the scale factor N by use of the membership function. The threshold determined by this method is consecutive and smooth, and it is closer to the fact than that of the initial N-sigma algorithm. The GPS signal and single-tone (CW) interference (that is, typical narrow-band interference) are implemented in the simulation, and the results are presented to demonstrate the validity of the new algorithm.
基金supported by a grant from the national High Technology Research and development Program of China(863 Program)(No.2012AA01A502)National Natural Science Foundation of China(No.61179006)Science and Technology Support Program of Sichuan Province(No.2014GZX0004)
文摘To overcome the inter-carrier interference (ICI) of orthogonal frequency division multiplexing (OFDM) systems subject to unknown carrier frequency offset (CFO) and multipath, this paper develops a blind adaptive interference suppression scheme based on independent component analysis (ICA). Taking into account statistical independence of subcarriers' signals of OFDM, the signal recovery mechanism is investigated to achieve the goal of blind equalization. The received OFDM signals can be considered as the mixed observation signals. The effect of CFO and multipath corresponds to the mixing matrix in the problem of blind source separation (BSS) framework. In this paper, the ICA- based OFDM system model is built, and the proposed ICA-based detector is exploited to extract source signals from the observation of a received mixture based on the assumption of statistical independence between the sources. The blind separation technique can increase spectral efficiency and provide robustness performance against erroneous parameter estimation problem. Theoretical analysis and simulation results show that compared with the conventional pilot-based scheme, the improved performance of OFDM systems is obtained by the proposed ICA-based detection technique.
文摘Radio Frequency Interference (RFI) degrades the quality of focused Ultra-WideBand Syn- thetic Aperture Radar (UWB SAR) images. From both the theoretical analysis and real data valida- tion, it is concluded that target echo and RFI have different Region Of Support (ROS) in 2-D fast- time wavenumber and aperture wavenumber domain. Consequently, a novel adaptive filter is pro- posed according to the Wiener optimum criterion on the distinct ROS characteristics of target echo and RFI. Compared with the notch filter and the Least Mean Square (LMS) adaptive filter in previ- ous literatures, the proposed method is more computationally efficient with satisfactory suppression results. In terms of Signal-to-Interference Ratio Improvement (SIRI) and processing time, the per- formance of the proposed adaptive filter is verified with the field data collected with a UWB SAR system.
文摘A new method of single sample polarization filtering is proposed. The algorithm is fast and suitable for the polarization processing of stationary or nonstationary polarized disturbed signals with one or more independent disturbances. A ground wave polarimetric radar with the ability of radio disturbance suppression is then introduced. Some numerical results demonstrate the effectiveness of single sample polarization filtering method for ground wave polarimetric radar.
基金supported by National Natural Science Foundation of China (Nos.61172107,61172110)National High Technical Research and Development Program (863 Program) of China (No.2015AA016306)+1 种基金Major Projects in Liaoning Province Science and Technology Innovation (No.201302001)Fundamental Research Funds for the Central Universities of China (No.DUT13LAB06)
文摘The 3-D beamforming scheme has elite as evolving interest because of its efficiency to empower assorted techniques such as vertical and horizontal domains and emanation beamforming according to subscriber's provisions. Usually, 3-D beamforming communication is set up on FDD/TDD approach those effects on the performance of spectrum and energy efficiency. Co-frequency and CoTime Full Duplex(CCFD) is an effective solution to improve the spectrum and energy efficiency by transmitting and receiving simultaneously in frequency and time domain. While, CCFD communication often face the self-interference issue when communication occurs, simultaneously. Consequently, in this paper a self-interference elimination by physical feedback channel in CCFD for 3-D Beamforming communication scheme is proposed to improve the over-all system performance in terms of energy and spectrum efficiency. The simulation and analytical outcomes demonstrated that the proposed system is superior than the traditional one.
基金Supported by grants from the Young Scientific and Technical InnovationFoundation of Fujian Province (No. 2004J067).
文摘Objective: To explore the inhibition of the expression of c-Myc in human hepatocellular carcinoma via vector-based RNA interference (RNAi). Methods: Two RNA interference DNA templates targeting c-Myc oncogene were designed via online software and synthesized. By ligation, the fragments were inserted into pSilencer 1.0-U6 to construct the recombinant siRNA expressing plasmids. The identified recombinants were introduced into BEL-7402 cells with Lipofactamine. The inhibition of c-Myc expression, together with the expression of CDK4, hTERT and Gadd45β in c-Myc down-regulated BEL-7402 cells, were analyzed by semi-quantitative RT-PCR. Results: Two recombinant plasmids pSic-myc-1 and pSic-myc-2, which direct the yields of siRNAs targeting c-Myc in cells, were constructed. Among which, pSic-myc-2 was shown to trigger a RNAi-mediated inhibition of expression of c-Myc in BEL-7402 by up to 90%. In c-Myc knockdown BEL-7402 cells, the expression of CDK4 and hTERT were down-regulated with a ratio of 85% and 57%, respectively, while the expression of Gadd45β was up-regulated by up to 110%. Conclusion: The expression of c-Myc in BEL-7402 could be suppressed by vector-based RNA interference successfully. The knockdown of c-Myc in turn resulted in the changes of expression of genes related to cell proliferation and apoptosis. Thus, our study provided a preliminary data in searching of a c-Myc-targeted RNAi therapy of human hepatocellular carcinoma.