Ovarian lesions are commonly encountered pathologies that cannot be categorized clinicoradiologically.Definite diagnosis is of great importance for therapeutic and prognostic purposes.Histopathology gives accurate dia...Ovarian lesions are commonly encountered pathologies that cannot be categorized clinicoradiologically.Definite diagnosis is of great importance for therapeutic and prognostic purposes.Histopathology gives accurate diagnosis in most cases.Few cases need supportive tests like immunohistochemistry.Objective:to study the histomorphological diversity of ovarian lesions,their age and location in North of Iraq(Mosul and Duhok).Patients and methods:In the period extended from January 2008 to December 2011,161 cases of ovarian lesions were collected from pathology departments in Azadi General Hospital“Duhok”and Al-Jamhori Teaching Hospital“Mosul”.Automated tissue processor was used for histologic study and Streptavidin-biotin method on paraffin sections was applied for immunohistochemistry.Result:There was a wide age range,most being in the third decade.The right ovaries were more common involved than the left.Histologically,58(36%)cases were non-neoplastic and 103 were neoplastic including 90(55.9%)benign and 9(5.6%)malignant tumors.The remaining 4(2.4%)cases comprised borderline serous cystadenoma.Conclusion:Most ovarian lesions were functional non-neoplastic followed by benign neoplastic.Apart from few cases,diagnosis was merely histological without any ancillary test.展开更多
Accompanying rapid developments in hepatic surgery,the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically.This has led to many...Accompanying rapid developments in hepatic surgery,the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically.This has led to many changes in the surgicopathological spectrum of PHSOLs,and has contributed to a theoretical basis for modern hepatic surgery and oncological pathology.Between 1982 and 2009 at the Eastern Hepatobiliary Surgery Hospital (EHBH) in Shanghai,31 901 patients underwent surgery and were diagnosed as having a PHSOL.In this paper,we present an analysis of the PHSOL cases at the EHBH for this time period,along with results from a systematic literature review.We describe a surgicopathological spectrum comprising more than 100 types of PHSOLs that can be stratified into three types:tumor-like,benign,and malignant.We also stratified the PHSOLs into six subtypes derived from hepatocytes;cholangiocytes;vascular,lymphoid and hemopoietic tissues;muscular,fibrous and adipose tissues;neural and neuroendocrine tissues;and miscellaneous tissues.The present study provides a new classification system that can be used as a current reference for clinicians and pathologists to make correct diagnoses and differential diagnoses among various PHSOLs.展开更多
A case of florid reactive periostitis ossificans(RPO) arising in a long bone is presented. This is a rare bone proliferation with a pronounced periosteal reaction. Less than 100 cases have been described in the litera...A case of florid reactive periostitis ossificans(RPO) arising in a long bone is presented. This is a rare bone proliferation with a pronounced periosteal reaction. Less than 100 cases have been described in the literature with far fewer outside the bones of the hand, feet, fingers, and toes. Although the etiology is unknown, a relationship to preceding trauma is suggested. The imaging and histologic features show an overlap with other bone lesions including bizarre parosteal osteochondromatous proliferation, subungual exostosis, and malignant surface tumors of bone and cartilage which include, periosteal and parosteal osteosarcoma. It is important to recognize the clinical presentation and diagnostic features of RPO as a benign entity so that it is not mistaken for a more aggressive neoplasm. We present a case of a right distal humeral lesion that on histopathological review revealed florid RPO. This diagnosis was not suspected on imaging studies, but was made on open biopsy of the mass. The patient remains disease free, years postoperatively. In addition to presenting this unique case report, we review the pertinent literature, and offer a differential diagnosis and treatment strategy for its management.展开更多
We describe an uncommon case of a patient with a metastatic adenocarcinoma of ovarian origin presented as a gastric subepithelial tumor(SET) and that was diagnosed by endoscopic ultrasound fine-needle biopsy(EUS-FNB)....We describe an uncommon case of a patient with a metastatic adenocarcinoma of ovarian origin presented as a gastric subepithelial tumor(SET) and that was diagnosed by endoscopic ultrasound fine-needle biopsy(EUS-FNB). Malignant gastric lesions are rarely metastatic and the primary tumor is mainly breast, lung, esophageal cancer or cutaneous melanoma. Gastric metastasis from ovarian cancer is unusual, presenting synchronously with the primary tumor but also several years later than the initial diagnosis. From an endoscopic point of view, gastric metastasis does not present specific features. They may mimic both a primary gastric tumor or, less frequently, an SET.This case demonstrates the importance of EUS-FNB in distinguishing SETs and how this may alter treatment and prognosis.展开更多
The descending duodenum is rarely involved in Schistosoma japonicum(S. japonicum) infection. Here, we report a case of acute Schistosoma infection, which presented with abdominal pain, abdominal distension and irregul...The descending duodenum is rarely involved in Schistosoma japonicum(S. japonicum) infection. Here, we report a case of acute Schistosoma infection, which presented with abdominal pain, abdominal distension and irregular fever. Tumor-like lesions were observed in the descending duodenum. Simultaneously, heterogeneity in hepatic perfusion was demonstrated by dynamic computed tomography scanning. Biopsy of the descending duodenum showed the deposition of Schistosoma eggs. Following administration of the antihelminthic drug praziquantel, the patient showed rapid clinical improvement. In conclusion, we report a patient with acute S. japonicum infection presenting as tumor-like lesions in the descending duodenum and heterogeneity of blood perfusion in liver parenchyma.展开更多
In the present investigation, gross and microscopic lesions of the ovaries were studied in two hundred and ten (210) adult non-pregnant she-camels. Fresh samples of ovaries were collected from she-camels at the point ...In the present investigation, gross and microscopic lesions of the ovaries were studied in two hundred and ten (210) adult non-pregnant she-camels. Fresh samples of ovaries were collected from she-camels at the point of slaughter in Al-Ahsa abattoir, Eastern region of Kingdom of Saudi Arabia. These samples were subjected to histopathological studies and stained by routine Hematoxylin and Eosin stain. Grossly, of the 210 ovarian tissues examined, 30 (14.28%) had ovarian lesions of one type or another, whereas 180 (85.71%) camels were apparently healthy. Only 6 (2.85%) ovaries showed unilateral ovarian hypoplasia, whereas 4 (1.9%) showed bilateral ovarian hypoplasia. Cystic ovaries were observed in a total of 13 of the collected samples of ovaries, of these 8 (3.8%) were diagnosed as follicular cystic ovaries, while 5 (2.38%) were luteal cystic ovaries. Ovarian abscess appeared in only one sample of the collected ovaries. While ovarian tumors were observed in a total of 6 of the collected samples distributed as, two fibromas, three dermoid cysts, and only one hemangioma. The present study indicates that follicular cysts, luteal cysts and ovarian hypoplasia were the most common ovarian disorders in non-pregnant she-camels in Al-Ahsa region of the Eastern Province of Kingdom of Saudi Arabia.展开更多
目的初步比较第四代达芬奇机器人辅助单孔腹腔镜手术与传统单孔腹腔镜手术治疗儿童及青少年卵巢良性病变的临床效果。方法回顾性分析2018年1月至2023年3月在武汉大学中南医院行第四代达芬奇机器人辅助单孔腹腔镜手术和传统单孔腹腔镜手...目的初步比较第四代达芬奇机器人辅助单孔腹腔镜手术与传统单孔腹腔镜手术治疗儿童及青少年卵巢良性病变的临床效果。方法回顾性分析2018年1月至2023年3月在武汉大学中南医院行第四代达芬奇机器人辅助单孔腹腔镜手术和传统单孔腹腔镜手术的儿童及青少年卵巢良性病变患者临床资料,采取第四代达芬奇机器人辅助单孔腹腔镜手术(robot-assisted laparoscopic single port surgery,R-LESS)13例(R-LESS组),采取传统单孔腹腔镜手术(laparoscopic single port surgery,LESS)22例(LESS组)。统计两组患儿手术时间、术中出血量、卵巢扭转情况、卵巢肿瘤体积、术中有无卵巢肿瘤破裂、是否放置引流管、术后并发症发生率、住院时间、住院费用以及随访情况。结果R-LESS组与LESS组手术时间[161.38(103.00,201.00)min比136.31(100.50,171.50)min]、术中出血量[21.15(10.00,32.50)mL比45.23(10.00,50.00)mL]、卵巢扭转发生率(15%比32%)、术中卵巢肿瘤破裂发生率(23%比36%)、引流管放置率(23%比23%)、术后并发症发生率(8%比6%)以及随访时间[20.70(11.00,29.50)个月比28.09(9.25,46.25)个月]比较,差异均无统计学意义(P>0.05);R-LESS组较LESS组术后住院时间减少[4.23(3.00,5.00)d比5.05(3.75,6.25)d],住院费用增多[(40557.01±4036.29)元比(26456.32±6413.30)元],差异有统计学意义(P<0.05)。结论R-LESS手术治疗儿童及青少年卵巢良性病变安全可行。与LESS手术相比,R-LESS术后患儿恢复更快,但住院费用较高。R-LESS手术可作为治疗儿童及青少年卵巢良性病变的一种选择,未来仍需进行大样本对比研究以进一步验证。展开更多
文摘Ovarian lesions are commonly encountered pathologies that cannot be categorized clinicoradiologically.Definite diagnosis is of great importance for therapeutic and prognostic purposes.Histopathology gives accurate diagnosis in most cases.Few cases need supportive tests like immunohistochemistry.Objective:to study the histomorphological diversity of ovarian lesions,their age and location in North of Iraq(Mosul and Duhok).Patients and methods:In the period extended from January 2008 to December 2011,161 cases of ovarian lesions were collected from pathology departments in Azadi General Hospital“Duhok”and Al-Jamhori Teaching Hospital“Mosul”.Automated tissue processor was used for histologic study and Streptavidin-biotin method on paraffin sections was applied for immunohistochemistry.Result:There was a wide age range,most being in the third decade.The right ovaries were more common involved than the left.Histologically,58(36%)cases were non-neoplastic and 103 were neoplastic including 90(55.9%)benign and 9(5.6%)malignant tumors.The remaining 4(2.4%)cases comprised borderline serous cystadenoma.Conclusion:Most ovarian lesions were functional non-neoplastic followed by benign neoplastic.Apart from few cases,diagnosis was merely histological without any ancillary test.
基金Supported by The National Nature Science Foundation of China,No.30872506 and No.81072026
文摘Accompanying rapid developments in hepatic surgery,the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically.This has led to many changes in the surgicopathological spectrum of PHSOLs,and has contributed to a theoretical basis for modern hepatic surgery and oncological pathology.Between 1982 and 2009 at the Eastern Hepatobiliary Surgery Hospital (EHBH) in Shanghai,31 901 patients underwent surgery and were diagnosed as having a PHSOL.In this paper,we present an analysis of the PHSOL cases at the EHBH for this time period,along with results from a systematic literature review.We describe a surgicopathological spectrum comprising more than 100 types of PHSOLs that can be stratified into three types:tumor-like,benign,and malignant.We also stratified the PHSOLs into six subtypes derived from hepatocytes;cholangiocytes;vascular,lymphoid and hemopoietic tissues;muscular,fibrous and adipose tissues;neural and neuroendocrine tissues;and miscellaneous tissues.The present study provides a new classification system that can be used as a current reference for clinicians and pathologists to make correct diagnoses and differential diagnoses among various PHSOLs.
基金Supported by The University of Alabama at Birmingham,Alabama and The Orthopaedic Center,Birmingham,AL,United States
文摘A case of florid reactive periostitis ossificans(RPO) arising in a long bone is presented. This is a rare bone proliferation with a pronounced periosteal reaction. Less than 100 cases have been described in the literature with far fewer outside the bones of the hand, feet, fingers, and toes. Although the etiology is unknown, a relationship to preceding trauma is suggested. The imaging and histologic features show an overlap with other bone lesions including bizarre parosteal osteochondromatous proliferation, subungual exostosis, and malignant surface tumors of bone and cartilage which include, periosteal and parosteal osteosarcoma. It is important to recognize the clinical presentation and diagnostic features of RPO as a benign entity so that it is not mistaken for a more aggressive neoplasm. We present a case of a right distal humeral lesion that on histopathological review revealed florid RPO. This diagnosis was not suspected on imaging studies, but was made on open biopsy of the mass. The patient remains disease free, years postoperatively. In addition to presenting this unique case report, we review the pertinent literature, and offer a differential diagnosis and treatment strategy for its management.
文摘We describe an uncommon case of a patient with a metastatic adenocarcinoma of ovarian origin presented as a gastric subepithelial tumor(SET) and that was diagnosed by endoscopic ultrasound fine-needle biopsy(EUS-FNB). Malignant gastric lesions are rarely metastatic and the primary tumor is mainly breast, lung, esophageal cancer or cutaneous melanoma. Gastric metastasis from ovarian cancer is unusual, presenting synchronously with the primary tumor but also several years later than the initial diagnosis. From an endoscopic point of view, gastric metastasis does not present specific features. They may mimic both a primary gastric tumor or, less frequently, an SET.This case demonstrates the importance of EUS-FNB in distinguishing SETs and how this may alter treatment and prognosis.
基金Supported by National Natural Science Foundation of China,No.81270506 and No.81570555Clinical Research Physician Program of Tongji Medical College,No.HUST(2017)
文摘The descending duodenum is rarely involved in Schistosoma japonicum(S. japonicum) infection. Here, we report a case of acute Schistosoma infection, which presented with abdominal pain, abdominal distension and irregular fever. Tumor-like lesions were observed in the descending duodenum. Simultaneously, heterogeneity in hepatic perfusion was demonstrated by dynamic computed tomography scanning. Biopsy of the descending duodenum showed the deposition of Schistosoma eggs. Following administration of the antihelminthic drug praziquantel, the patient showed rapid clinical improvement. In conclusion, we report a patient with acute S. japonicum infection presenting as tumor-like lesions in the descending duodenum and heterogeneity of blood perfusion in liver parenchyma.
文摘In the present investigation, gross and microscopic lesions of the ovaries were studied in two hundred and ten (210) adult non-pregnant she-camels. Fresh samples of ovaries were collected from she-camels at the point of slaughter in Al-Ahsa abattoir, Eastern region of Kingdom of Saudi Arabia. These samples were subjected to histopathological studies and stained by routine Hematoxylin and Eosin stain. Grossly, of the 210 ovarian tissues examined, 30 (14.28%) had ovarian lesions of one type or another, whereas 180 (85.71%) camels were apparently healthy. Only 6 (2.85%) ovaries showed unilateral ovarian hypoplasia, whereas 4 (1.9%) showed bilateral ovarian hypoplasia. Cystic ovaries were observed in a total of 13 of the collected samples of ovaries, of these 8 (3.8%) were diagnosed as follicular cystic ovaries, while 5 (2.38%) were luteal cystic ovaries. Ovarian abscess appeared in only one sample of the collected ovaries. While ovarian tumors were observed in a total of 6 of the collected samples distributed as, two fibromas, three dermoid cysts, and only one hemangioma. The present study indicates that follicular cysts, luteal cysts and ovarian hypoplasia were the most common ovarian disorders in non-pregnant she-camels in Al-Ahsa region of the Eastern Province of Kingdom of Saudi Arabia.
文摘目的初步比较第四代达芬奇机器人辅助单孔腹腔镜手术与传统单孔腹腔镜手术治疗儿童及青少年卵巢良性病变的临床效果。方法回顾性分析2018年1月至2023年3月在武汉大学中南医院行第四代达芬奇机器人辅助单孔腹腔镜手术和传统单孔腹腔镜手术的儿童及青少年卵巢良性病变患者临床资料,采取第四代达芬奇机器人辅助单孔腹腔镜手术(robot-assisted laparoscopic single port surgery,R-LESS)13例(R-LESS组),采取传统单孔腹腔镜手术(laparoscopic single port surgery,LESS)22例(LESS组)。统计两组患儿手术时间、术中出血量、卵巢扭转情况、卵巢肿瘤体积、术中有无卵巢肿瘤破裂、是否放置引流管、术后并发症发生率、住院时间、住院费用以及随访情况。结果R-LESS组与LESS组手术时间[161.38(103.00,201.00)min比136.31(100.50,171.50)min]、术中出血量[21.15(10.00,32.50)mL比45.23(10.00,50.00)mL]、卵巢扭转发生率(15%比32%)、术中卵巢肿瘤破裂发生率(23%比36%)、引流管放置率(23%比23%)、术后并发症发生率(8%比6%)以及随访时间[20.70(11.00,29.50)个月比28.09(9.25,46.25)个月]比较,差异均无统计学意义(P>0.05);R-LESS组较LESS组术后住院时间减少[4.23(3.00,5.00)d比5.05(3.75,6.25)d],住院费用增多[(40557.01±4036.29)元比(26456.32±6413.30)元],差异有统计学意义(P<0.05)。结论R-LESS手术治疗儿童及青少年卵巢良性病变安全可行。与LESS手术相比,R-LESS术后患儿恢复更快,但住院费用较高。R-LESS手术可作为治疗儿童及青少年卵巢良性病变的一种选择,未来仍需进行大样本对比研究以进一步验证。