Artificial Intelligence (AI) has progressively impacted healthcare around the world. The increasing need for readily available mental health services, coupled with the swift advancement of novel technologies, prompts ...Artificial Intelligence (AI) has progressively impacted healthcare around the world. The increasing need for readily available mental health services, coupled with the swift advancement of novel technologies, prompts conversations over the viability of psychotherapy approaches using engagements with AI. Despite the positive impacts, there are recognizable drawbacks associated with the application of AI in psychotherapy. Establishing a therapeutic alliance is difficult for non-human entities. Psychotherapy is a task too complex for limited artificial intelligence. AI appears capable of handling jobs that are clearly defined and relatively straightforward. Besides, AI malfunctions, data confidentiality, informed consent, and risk of bias are potential concerns. We present a literature update of possible solutions to overcome these concerns.展开更多
Despite increasing evidence about the value and importance of breastfeeding, less than half of the world's infants and youngchildren (aged 0-36 months) are breastfed as recommended. This Series paper examines the ...Despite increasing evidence about the value and importance of breastfeeding, less than half of the world's infants and youngchildren (aged 0-36 months) are breastfed as recommended. This Series paper examines the social, political, and economic reasonsfor this problem. First, this paper highlights the power of the commercial milk formula (CMF) industry to commodify the feedingof infants and young children;influence policy at both national and international levels in ways that grow and sustain CMF markets;and externalise the social, environmental, and economic costs of CMF. Second, this paper examines how breastfeeding isundermined by economic policies and systems that ignore the value of care work by women, including breastfeeding, and by theinadequacy of maternity rights protection across the world, especially for poorer women. Third, this paper presents three reasonswhy health systems often do not provide adequate breastfeeding protection, promotion, and support. These reasons are thegendered and biomedical power systems that deny women-centred and culturally appropriate care;the economic and ideologicalfactors that accept, and even encourage, commercial influence and conflicts of interest;and the fiscal and economic policies thatleave governments with insufficient funds to adequately protect, promote, and support breastfeeding. We outline six sets of widerangingsocial, political, and economic reforms required to overcome these deeply embedded commercial and structural barriersto breastfeeding.展开更多
Dear Editor, This letter is concerned with the evolution strategy for addressing multi-objective feature selection problems in classification. Previous methods suffer from limitations such as being trapped in local op...Dear Editor, This letter is concerned with the evolution strategy for addressing multi-objective feature selection problems in classification. Previous methods suffer from limitations such as being trapped in local optima and lacking stability. To overcome them, we propose a novel eliteguided mechanism based on information theory. Firstly, an elite solution is generated through a dimension reduction strategy and incorporated to the initialization population.展开更多
Intelligent and connected vehicles(ICVs)are confronted with critically complex traffic scenarios and safety challenges that have attracted increasing attention from academia and industry.The intelligent safety of ICVs...Intelligent and connected vehicles(ICVs)are confronted with critically complex traffic scenarios and safety challenges that have attracted increasing attention from academia and industry.The intelligent safety of ICVs involves several technologies and requires the common efforts of researchers and engineers,including the safety of the intended functionality(SOTIF),the safety of artificial intelligence,the intricacies of cybersecurity,and ethical dilemmas.Ensuring the intelligent safety of ICVs presents substantial chal-lenges in both research and commercialization,particularly SOTIF,which refers to the absence of unreasonable risk owing to hazards resulting from functional insufficiencies of the intended functiona-lity or reasonably foreseeable misuse by person.Because of the limited scene coverage ability of training samples and the practical application conditions without boundary restrictions,it is very dif-ficult to find the functional insufficiency of the intended function-ality and overcome it under dynamic unknown scenarios,which is also the source of SOTIF.展开更多
Precision medicine is a growing field worldwide.Despite its potential benefit to many patients,several major obstacles must be overcome before precision medicine can be more widely used in clinical practice.The main o...Precision medicine is a growing field worldwide.Despite its potential benefit to many patients,several major obstacles must be overcome before precision medicine can be more widely used in clinical practice.The main obstacles are associated with the quality of samples used for genomic analysis。展开更多
Osteoporosis,a metabolic bone disease characterized by low bone mineral density and deterioration of bone microarchitecture,has led to a high risk of fatal osteoporotic fractures worldwide.Accumulating evidence has re...Osteoporosis,a metabolic bone disease characterized by low bone mineral density and deterioration of bone microarchitecture,has led to a high risk of fatal osteoporotic fractures worldwide.Accumulating evidence has revealed that sexual dimorphism is a notable feature of osteoporosis,with sex-specific differences in epidemiology and pathogenesis.Specifically,females are more susceptible than males to osteoporosis,while males are more prone to disability or death from the disease.To date,sex chromosome abnormalities and steroid hormones have been proven to contribute greatly to sexual dimorphism in osteoporosis by regulating the functions of bone cells.Understanding the sex-specific differences in osteoporosis and its related complications is essential for improving treatment strategies tailored to women and men.This literature review focuses on the mechanisms underlying sexual dimorphism in osteoporosis,mainly in a population of aging patients,chronic glucocorticoid administration,and diabetes.Moreover,we highlight the implications of sexual dimorphism for developing therapeutics and preventive strategies and screening approaches tailored to women and men.Additionally,the challenges in translating bench research to bedside treatments and future directions to overcome these obstacles will be discussed.展开更多
Leprosy Annihilator Director:Lin Haiyan Length:Two Episodes Producer:Documentary Center of Shandong Radio and Television Broadcasting Platform:bilibili The film series narrate the story of a 70-year-long national init...Leprosy Annihilator Director:Lin Haiyan Length:Two Episodes Producer:Documentary Center of Shandong Radio and Television Broadcasting Platform:bilibili The film series narrate the story of a 70-year-long national initiative to prevent and control leprosy.Several generations of Chinese medical professionals worked tirelessly to overcome the infectious disease that has plagued humanity for thousands of years.The film shares the little-known history with an impressive production to increase awareness of the endeavor in modern times.展开更多
A young Chinese baker became a world champion by pursuing his passion and working hard to overcome challenges.Adancing lion,giant panda,roller coaster,and a merry-go-round in eye-popping shapes-when these elements are...A young Chinese baker became a world champion by pursuing his passion and working hard to overcome challenges.Adancing lion,giant panda,roller coaster,and a merry-go-round in eye-popping shapes-when these elements are grouped together,what kind of magic can happen?Winning magic if you are Gong Xin,a Gen Z baker from China who made a one-meter-high artistic creation using all of these elements.He won the ninth World Bread Competition(Mondial du Pain)as a result.Many Chinese found it hard to believe what he had done after seeing pictures.“This is virtually a work of art,”and“it is equivalent to a foreigner taking first place in a dumpling-making contest in China,”were some of the many online comments.As the host of the competition,France,famous for its bread-making techniques,was beaten into second place,leaving the French media shocked that a Chinese baker had won the famous world bread contest.展开更多
China strives to overcome challenges to maximising the value of data.Data plays a crucial role in our daily lives,enabling personalised services based on consumer habits,granting loans based on credit histories,and fa...China strives to overcome challenges to maximising the value of data.Data plays a crucial role in our daily lives,enabling personalised services based on consumer habits,granting loans based on credit histories,and facilitating telemedicine through the use of medical data.These applications are made possible by the processing and exchange of large volumes of data.展开更多
Over decades,he faithfully adhered to the"life forbidden zone,"where he always fought on the front line of maintaining the Qinghai-Xizang Railway at an area with an average altitude of 4,700 meters and above...Over decades,he faithfully adhered to the"life forbidden zone,"where he always fought on the front line of maintaining the Qinghai-Xizang Railway at an area with an average altitude of 4,700 meters and above.It is at this place where he led his team to face the hardest"obstacles"and overcome all sorts of problems and difficulties,thanks to the harsh freezing temperature environment.It is the place where he and his team have worked together to achieve a miraculous maintenance of the frozen-soil-featured railway line on top of the world.He is Gao Qiansheng.展开更多
Catastrophic forgetting describes the fact that machine learning models will likely forget the knowledge of previously learned tasks after the learning process of a new one.It is a vital problem in the continual learn...Catastrophic forgetting describes the fact that machine learning models will likely forget the knowledge of previously learned tasks after the learning process of a new one.It is a vital problem in the continual learning scenario and recently has attracted tremendous concern across different communities.We explore the catastrophic forgetting phenomena in the context of quantum machine learning.It is found that,similar to those classical learning models based on neural networks,quantum learning systems likewise suffer from such forgetting problem in classification tasks emerging from various application scenes.We show that based on the local geometrical information in the loss function landscape of the trained model,a uniform strategy can be adapted to overcome the forgetting problem in the incremental learning setting.Our results uncover the catastrophic forgetting phenomena in quantum machine learning and offer a practical method to overcome this problem,which opens a new avenue for exploring potential quantum advantages towards continual learning.展开更多
文摘Artificial Intelligence (AI) has progressively impacted healthcare around the world. The increasing need for readily available mental health services, coupled with the swift advancement of novel technologies, prompts conversations over the viability of psychotherapy approaches using engagements with AI. Despite the positive impacts, there are recognizable drawbacks associated with the application of AI in psychotherapy. Establishing a therapeutic alliance is difficult for non-human entities. Psychotherapy is a task too complex for limited artificial intelligence. AI appears capable of handling jobs that are clearly defined and relatively straightforward. Besides, AI malfunctions, data confidentiality, informed consent, and risk of bias are potential concerns. We present a literature update of possible solutions to overcome these concerns.
文摘Despite increasing evidence about the value and importance of breastfeeding, less than half of the world's infants and youngchildren (aged 0-36 months) are breastfed as recommended. This Series paper examines the social, political, and economic reasonsfor this problem. First, this paper highlights the power of the commercial milk formula (CMF) industry to commodify the feedingof infants and young children;influence policy at both national and international levels in ways that grow and sustain CMF markets;and externalise the social, environmental, and economic costs of CMF. Second, this paper examines how breastfeeding isundermined by economic policies and systems that ignore the value of care work by women, including breastfeeding, and by theinadequacy of maternity rights protection across the world, especially for poorer women. Third, this paper presents three reasonswhy health systems often do not provide adequate breastfeeding protection, promotion, and support. These reasons are thegendered and biomedical power systems that deny women-centred and culturally appropriate care;the economic and ideologicalfactors that accept, and even encourage, commercial influence and conflicts of interest;and the fiscal and economic policies thatleave governments with insufficient funds to adequately protect, promote, and support breastfeeding. We outline six sets of widerangingsocial, political, and economic reforms required to overcome these deeply embedded commercial and structural barriersto breastfeeding.
基金supported in part by the Japan Society for the Promotion of Science (JSPS) KAKENHI (JP22H 03643)the Japan Science and Technology Agency (JST) (the establishment of university fellowships towards the creation of science technology innovation) (JPMJFS2115)。
文摘Dear Editor, This letter is concerned with the evolution strategy for addressing multi-objective feature selection problems in classification. Previous methods suffer from limitations such as being trapped in local optima and lacking stability. To overcome them, we propose a novel eliteguided mechanism based on information theory. Firstly, an elite solution is generated through a dimension reduction strategy and incorporated to the initialization population.
文摘Intelligent and connected vehicles(ICVs)are confronted with critically complex traffic scenarios and safety challenges that have attracted increasing attention from academia and industry.The intelligent safety of ICVs involves several technologies and requires the common efforts of researchers and engineers,including the safety of the intended functionality(SOTIF),the safety of artificial intelligence,the intricacies of cybersecurity,and ethical dilemmas.Ensuring the intelligent safety of ICVs presents substantial chal-lenges in both research and commercialization,particularly SOTIF,which refers to the absence of unreasonable risk owing to hazards resulting from functional insufficiencies of the intended functiona-lity or reasonably foreseeable misuse by person.Because of the limited scene coverage ability of training samples and the practical application conditions without boundary restrictions,it is very dif-ficult to find the functional insufficiency of the intended function-ality and overcome it under dynamic unknown scenarios,which is also the source of SOTIF.
基金the Japan Agency for Medical Research and Development(Grant Nos.20lk0201002j0001,21lk0201005j0001,and 22lk0201007j0001)。
文摘Precision medicine is a growing field worldwide.Despite its potential benefit to many patients,several major obstacles must be overcome before precision medicine can be more widely used in clinical practice.The main obstacles are associated with the quality of samples used for genomic analysis。
基金the National Natural Science Foundation of China (Grants 82170844 and 82270613)the Sichuan Science and Technology Program (Grants 2022YFH0045 and 2022YFH0102)+5 种基金the 111 Project (Grant B18035)the 1·3·5 project for Disciplines of Excellence at West China Hospital, Sichuan University (Grant ZYGD22007 and ZYJC21004)Ningbo Top Medical and Health Research Program (No.2023030514)Ningbo Medical and Health Brand Discipline (Grant No.PPXK2018–02)Ningbo Clinical Research Center for Otolaryngology Head and Neck Disease (Grant No.2022L005)the Ministry of Education, Singapore, (Grant MOE-000395-00) to LYC.
文摘Osteoporosis,a metabolic bone disease characterized by low bone mineral density and deterioration of bone microarchitecture,has led to a high risk of fatal osteoporotic fractures worldwide.Accumulating evidence has revealed that sexual dimorphism is a notable feature of osteoporosis,with sex-specific differences in epidemiology and pathogenesis.Specifically,females are more susceptible than males to osteoporosis,while males are more prone to disability or death from the disease.To date,sex chromosome abnormalities and steroid hormones have been proven to contribute greatly to sexual dimorphism in osteoporosis by regulating the functions of bone cells.Understanding the sex-specific differences in osteoporosis and its related complications is essential for improving treatment strategies tailored to women and men.This literature review focuses on the mechanisms underlying sexual dimorphism in osteoporosis,mainly in a population of aging patients,chronic glucocorticoid administration,and diabetes.Moreover,we highlight the implications of sexual dimorphism for developing therapeutics and preventive strategies and screening approaches tailored to women and men.Additionally,the challenges in translating bench research to bedside treatments and future directions to overcome these obstacles will be discussed.
文摘Leprosy Annihilator Director:Lin Haiyan Length:Two Episodes Producer:Documentary Center of Shandong Radio and Television Broadcasting Platform:bilibili The film series narrate the story of a 70-year-long national initiative to prevent and control leprosy.Several generations of Chinese medical professionals worked tirelessly to overcome the infectious disease that has plagued humanity for thousands of years.The film shares the little-known history with an impressive production to increase awareness of the endeavor in modern times.
文摘A young Chinese baker became a world champion by pursuing his passion and working hard to overcome challenges.Adancing lion,giant panda,roller coaster,and a merry-go-round in eye-popping shapes-when these elements are grouped together,what kind of magic can happen?Winning magic if you are Gong Xin,a Gen Z baker from China who made a one-meter-high artistic creation using all of these elements.He won the ninth World Bread Competition(Mondial du Pain)as a result.Many Chinese found it hard to believe what he had done after seeing pictures.“This is virtually a work of art,”and“it is equivalent to a foreigner taking first place in a dumpling-making contest in China,”were some of the many online comments.As the host of the competition,France,famous for its bread-making techniques,was beaten into second place,leaving the French media shocked that a Chinese baker had won the famous world bread contest.
文摘China strives to overcome challenges to maximising the value of data.Data plays a crucial role in our daily lives,enabling personalised services based on consumer habits,granting loans based on credit histories,and facilitating telemedicine through the use of medical data.These applications are made possible by the processing and exchange of large volumes of data.
文摘Over decades,he faithfully adhered to the"life forbidden zone,"where he always fought on the front line of maintaining the Qinghai-Xizang Railway at an area with an average altitude of 4,700 meters and above.It is at this place where he led his team to face the hardest"obstacles"and overcome all sorts of problems and difficulties,thanks to the harsh freezing temperature environment.It is the place where he and his team have worked together to achieve a miraculous maintenance of the frozen-soil-featured railway line on top of the world.He is Gao Qiansheng.
基金supported by the Start-Up Fund from Tsinghua University(Grant No.53330300320)the National Natural Science Foundation of China(Grant No.12075128)the Shanghai Qi Zhi Institute。
文摘Catastrophic forgetting describes the fact that machine learning models will likely forget the knowledge of previously learned tasks after the learning process of a new one.It is a vital problem in the continual learning scenario and recently has attracted tremendous concern across different communities.We explore the catastrophic forgetting phenomena in the context of quantum machine learning.It is found that,similar to those classical learning models based on neural networks,quantum learning systems likewise suffer from such forgetting problem in classification tasks emerging from various application scenes.We show that based on the local geometrical information in the loss function landscape of the trained model,a uniform strategy can be adapted to overcome the forgetting problem in the incremental learning setting.Our results uncover the catastrophic forgetting phenomena in quantum machine learning and offer a practical method to overcome this problem,which opens a new avenue for exploring potential quantum advantages towards continual learning.
