Accurate watermelon yield estimation is crucial to the agricultural value chain,as it guides the allocation of agricultural resources as well as facilitates inventory and logistics planning.The conventional method of ...Accurate watermelon yield estimation is crucial to the agricultural value chain,as it guides the allocation of agricultural resources as well as facilitates inventory and logistics planning.The conventional method of watermelon yield estimation relies heavily onmanual labor,which is both time-consuming and labor-intensive.To address this,this work proposes an algorithmic pipeline that utilizes unmanned aerial vehicle(UAV)videos for detection and counting of watermelons.This pipeline uses You Only Look Once version 8 s(YOLOv8s)with panorama stitching and overlap partitioning,which facilitates the overall number estimation ofwatermelons in field.The watermelon detection model,based on YOLOv8s and obtained using transfer learning,achieved a detection accuracy of 99.20%,demonstrating its potential for application in yield estimation.The panorama stitching and overlap partitioning based detection and counting method uses panoramic images as input and effectively mitigates the duplications comparedwith the video tracking based detection and countingmethod.The counting accuracy reached over 96.61%,proving a promising application for yield estimation.The high accuracy demonstrates the feasibility of applying this method for overall yield estimation in large watermelon fields.展开更多
Capacity reduction is a major problem faced by wireless mesh networks. An efficient way to alleviate this problem is proper channel assignment. Current end-toend channel assignment schemes usually focus on the case wh...Capacity reduction is a major problem faced by wireless mesh networks. An efficient way to alleviate this problem is proper channel assignment. Current end-toend channel assignment schemes usually focus on the case where channels in distinct frequency bands are assigned to mesh access and backbone, but actually backbone network and access network can use the same IEEE 802.11 technology. Besides, these channel assignment schemes only utilize orthogonal channels to perform channel assignment, and the resulting network interference dramatically degrades network performance. Moreover, Internet-oriented traffic is considered only, and peerto-peer traffic is omitted, or vice versa. The traffic type does not match the practical network. In this paper, we explore how to exploit partially overlapped channels to perform endto-end channel assignment in order to achieve effective end-to-end flow transmissions. The proposed flow-based end-to-end channel assignment schemes can conquer the limitations aforementioned. Simulations reveal that loadaware channel assignment can be applied to networks with stable traffic load, and it can achieve near-optimal performance; Traffic-irrelevant channel assignment is suitable for networks with frequent change of traffic load,and it can achieve good balance between performance and overhead. Also, partially overlapped channels' capability of improving network performance is situation-dependent, they should be used carefully.展开更多
This paper investigates a wireless system with multi-Unmanned Aerial Vehicles(UAVs)for improving the overall throughput.In contrast to previous studies that optimize the locations of UAVs and channel assignment separa...This paper investigates a wireless system with multi-Unmanned Aerial Vehicles(UAVs)for improving the overall throughput.In contrast to previous studies that optimize the locations of UAVs and channel assignment separately,this paper considers the two issues jointly by exploiting Partially Overlapped Channels(POCs).The optimization problem of maximizing network throughput is formulated as a non-convex and non-linear problem.In order to find a practical solution,the problem is decomposed into two subproblems,which are iteratively optimized.First,the optimal locations of UAVs are determined under a fixed channel assignment scheme by solving the mixed-integer second-order cone problem.Second,an efficient POC allocation scheme is determined via the proposed channel assignment algorithm.Simulation results show that the proposed approach not only significantly improves system throughput and service reliability compared with the cases in which only orthogonal channels and stationary UAVs are considered,but also achieves similar performance using the exhaustive search algorithm with lower time complexity.展开更多
We present our experimental ablation results for partially overlapped dual nanosecond laser beams(PO-DB)on metal and glass surfaces.Numerical simulations are performed to evaluate the crater reduction potential of the...We present our experimental ablation results for partially overlapped dual nanosecond laser beams(PO-DB)on metal and glass surfaces.Numerical simulations are performed to evaluate the crater reduction potential of the PO-DB setup.Damage probability experiments proved the collaboration of two beams within the overlap region.Bright-field and three-dimensional profile measurements verify the reduced ablation area from the proposed PODB scheme.Laser-induced plasma is generated when transparent glass is ablated.Atomic emission of Na I(~589.95nm)shows comparable signal between the PO-DB set and the traditional single laser beam set.The proposed PO-DB ablation mechanism could also be applied to femtosecond laser systems.展开更多
Nowadays,wireless local area network(WLAN)has become prevalent Internet access due to its low-cost gadgets,flexible coverage and hasslefree simple wireless installation.WLAN facilitates wireless Internet services to u...Nowadays,wireless local area network(WLAN)has become prevalent Internet access due to its low-cost gadgets,flexible coverage and hasslefree simple wireless installation.WLAN facilitates wireless Internet services to users with mobile devices like smart phones,tablets,and laptops through deployment of multiple access points(APs)in a network field.Every AP operates on a frequency band called channel.Popular wireless standard such as IEEE 802.11n has a limited number of channels where frequency spectrum of adjacent channels overlaps partially with each other.In a crowded environment,users may experience poor Internet services due to channel collision i.e.,interference from surrounding APs that affects the performance of the WLAN system.Therefore,it becomes a challenge to maintain expected performance in a crowded environment.A mathematical model of throughput considering interferences from surrounding APs can play an important role to set up a WLAN system properly.While set up,assignment of channels considering interference can maximize network performance.In this paper,we investigate the signal propagation of APs under interference of partially overlapping channels for both bonded and non-bonded channels.Then,a throughput estimation model is proposed using difference of operating channels and received signal strength indicator(RSSI).Then,a channel assignment algorithm is introduced using proposed throughput estimation model.Finally,the efficiency of the proposal is verified by numerical experiments using simulator.The results show that the proposal selects the best channel combination of bonded and non-bonded channels that maximize the performance.展开更多
In this paper, according to the AR4JA codes in deep space communication, two kinds of iterative decoding including partly parallel decoding and overlapped partly parallel decoding are analyzed, and the advantages and ...In this paper, according to the AR4JA codes in deep space communication, two kinds of iterative decoding including partly parallel decoding and overlapped partly parallel decoding are analyzed, and the advantages and disadvantages of them are listed. A modified overlapped partly parallel decoding that not only inherits the advantages of the two algorithms, but also overcomes the shortcomings of the two algorithms is proposed. The simulation results show that the three kinds of decoding have the same decoding performance; modified overlapped partly parallel decoding improves the iterative convergence rate and the throughput of system.展开更多
In this paper, a locally non-orthogonal overlapping Yee (OY) FDTD method is proposed in order to accurately calculates the optical force on dielectric and dispersive nanoparticles. It extends our previous work to geom...In this paper, a locally non-orthogonal overlapping Yee (OY) FDTD method is proposed in order to accurately calculates the optical force on dielectric and dispersive nanoparticles. It extends our previous work to geometries with sharp corners and dispersive materials. In addition to consistently achieving the smallest errors in comparison to the standard FDTD method, the OY approach is a stable non-orthogonal FDTD method that attains second-order convergence when sharp corners are present.展开更多
BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitor...BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitors(PPIs)are considered the referring medications for GERD.Nevertheless,PPIs must be managed carefully because their use,especially chronic,could be linked with some adverse effects.An effective and safe alternative pharmacological tool for GERD is needed.After the identification of potentially new medications to flank PPIs,it is mandatory to revise and improve good clinical practices even through a consensus process.AIM To optimize diagnosis and treatment guidelines for GERD through a consensus based on Delphi method.METHODS The availability of clinical studies describing the action of the multicomponent/multitarget medication Nux vomica-Heel,subject of the consensus,is the basic prerequisite for the consensus itself.A modified Delphi process was used to reach a consensus among a panel of Italian GERD specialists on the overlapping approach PPIs/Nux vomica-Heel as a new intervention model for the management of GERD.The Voting Consensus group was composed of 49 Italian Medical Doctors with different specializations:Gastroenterology,otolaryngology,geriatrics,and general medicine.A scientific committee analyzed the literature,determined areas that required investigation(in agreement with the multiple-choice questionnaire results),and identified two topics of interest:(1)GERD disease;and(2)GERD treatment.Statements for each of these topics were then formulated and validated.The Delphi process involved two rounds of questioning submitted to the panel experts using an online platform.RESULTS According to their routinary GERD practice and current clinical evidence,the panel members provided feedback to each questionnaire statement.The experts evaluated 15 statements and reached consensus on all 15.The statements regarding the GERD disease showed high levels of agreement,with consensus ranging from 70%to 92%.The statements regarding the GERD treatment also showed very high levels of agreement,with consensus ranging from 90%to 100%.This Delphi process was able to reach consensus among physicians in relevant aspects of GERD management,such as the adoption of a new approach to treat patients with GERD based on the overlapping between PPIs and Nux vomica-Heel.The consensus was unanimous among the physicians with different specializations,underlying the uniqueness of the agreement reached to identify in the overlapping approach between PPIs and Nux vomica-Heel a new intervention model for GERD management.The results support that an effective approach to deprescribe PPIs through a progressive decalage timetable(reducing PPIs administration to as-needed use),should be considered.CONCLUSION Nux vomica-Heel appears to be a valid opportunity for GERD treatment to favor the deprescription of PPIs and to maintain low disease activity together with the symptomatology remission.展开更多
The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision variables.However,in practical problems,the intera...The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision variables.However,in practical problems,the interaction among decision variables is intricate,leading to large group sizes and suboptimal optimization effects;hence a large-scale multi-objective optimization algorithm based on weighted overlapping grouping of decision variables(MOEAWOD)is proposed in this paper.Initially,the decision variables are perturbed and categorized into convergence and diversity variables;subsequently,the convergence variables are subdivided into groups based on the interactions among different decision variables.If the size of a group surpasses the set threshold,that group undergoes a process of weighting and overlapping grouping.Specifically,the interaction strength is evaluated based on the interaction frequency and number of objectives among various decision variables.The decision variable with the highest interaction in the group is identified and disregarded,and the remaining variables are then reclassified into subgroups.Finally,the decision variable with the strongest interaction is added to each subgroup.MOEAWOD minimizes the interactivity between different groups and maximizes the interactivity of decision variables within groups,which contributed to the optimized direction of convergence and diversity exploration with different groups.MOEAWOD was subjected to testing on 18 benchmark large-scale optimization problems,and the experimental results demonstrate the effectiveness of our methods.Compared with the other algorithms,our method is still at an advantage.展开更多
BACKGROUND Autoimmune hepatitis(AIH)and primary biliary cholangitis(PBC)are two common clinical autoimmune liver diseases,and some patients have both diseases;this feature is called AIH-PBC overlap syndrome.Autoimmune...BACKGROUND Autoimmune hepatitis(AIH)and primary biliary cholangitis(PBC)are two common clinical autoimmune liver diseases,and some patients have both diseases;this feature is called AIH-PBC overlap syndrome.Autoimmune thyroid disease(AITD)is the most frequently overlapping extrahepatic autoimmune disease.Immunoglobulin(IgG)4-related disease is an autoimmune disease recognized in recent years,characterized by elevated serum IgG4 levels and infiltration of IgG4-positive plasma cells in tissues.CASE SUMMARY A 68-year-old female patient was admitted with a history of right upper quadrant pain,anorexia,and jaundice on physical examination.Laboratory examination revealed elevated liver enzymes,multiple positive autoantibodies associated with liver and thyroid disease,and imaging and biopsy suggestive of pancreatitis,hepatitis,and PBC.A diagnosis was made of a rare and complex overlap syndrome of AIH,PBC,AITD,and IgG4-related disease.Laboratory features improved on treatment with ursodeoxycholic acid,methylprednisolone,and azathioprine.CONCLUSION This case highlights the importance of screening patients with autoimmune diseases for related conditions.展开更多
BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent years.Mycobacterium canariasense(M.canariasense)was first reported as an opportunistic pathogen in 2004,but there have been v...BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent years.Mycobacterium canariasense(M.canariasense)was first reported as an opportunistic pathogen in 2004,but there have been very few case reports since then.Nocardia is a genus of aerobic and Gram-positive bacilli,and these species are also opportunistic pathogens and in the Mycobacteriales order.Conventional methods for diagnosis of NTM are inefficient.Metagenomic next-generation sequencing(mNGS)can rapidly detect many pathogenic microorganisms,even rare species.Most NTM and Nocardia infections occur in immunocompromised patients with atypical clinical symptoms.There are no previous reports of infection by M.canariasense and Nocardia farcinica(N.farcinica),especially in immunocompetent patients.This case report describes an immunocompetent 52-year-old woman who had overlapping infections of M.canariasense,N.farcinica,and Candida parapsilosis(C.parapsilosis)based on mNGS.CASE SUMMARY A 52-year-old woman presented with a productive cough and chest pain for 2 wk,and recurrent episodes of moderate-grade fever for 1 wk.She received antibiotics for 1 wk at a local hospital,and experienced defervescence,but the productive cough and chest pain persisted.We collected samples of a lung lesion and alveolar lavage fluid for mNGS.The lung tissue was positive for M.canariasense,N.farcinica,and C.parapsilosis,and the alveolar lavage fluid was positive for M.canariasense.The diagnosis was pneumonia,and application of appropriate antibiotic therapy cured the patient.CONCLUSION Etiological diagnosis is critical for patients with infectious diseases.mNGS can identify rare and novel pathogens,and does not require a priori knowledge.展开更多
The quality of synthetic aperture radar(SAR)image degrades in the case of multiple imaging projection planes(IPPs)and multiple overlapping ship targets,and then the performance of target classification and recognition...The quality of synthetic aperture radar(SAR)image degrades in the case of multiple imaging projection planes(IPPs)and multiple overlapping ship targets,and then the performance of target classification and recognition can be influenced.For addressing this issue,a method for extracting ship targets with overlaps via the expectation maximization(EM)algorithm is pro-posed.First,the scatterers of ship targets are obtained via the target detection technique.Then,the EM algorithm is applied to extract the scatterers of a single ship target with a single IPP.Afterwards,a novel image amplitude estimation approach is pro-posed,with which the radar image of a single target with a sin-gle IPP can be generated.The proposed method can accom-plish IPP selection and targets separation in the image domain,which can improve the image quality and reserve the target information most possibly.Results of simulated and real mea-sured data demonstrate the effectiveness of the proposed method.展开更多
BACKGROUND Survival in patients with autoimmune liver disease overlap syndromes(AILDOS)compared to those with single autoimmune liver disease is unclear.AIM To investigate the survival of patients with AILDOS and asse...BACKGROUND Survival in patients with autoimmune liver disease overlap syndromes(AILDOS)compared to those with single autoimmune liver disease is unclear.AIM To investigate the survival of patients with AILDOS and assess the accuracy of non-invasive serum models for predicting liver-related death.METHODS Patients with AILDOS were defined as either autoimmune hepatitis and primary biliary cholangitis overlap(AIH-PBC)or autoimmune hepatitis and primary sclerosing cholangitis overlap(AIH-PSC)and were identified from three tertiary centres for this cohort study.Liver-related death or transplantation(liver-related mortality)was determined using a population-based data linkage system.Prognostic scores for liver-related death were compared for accuracy[including liver outcome score(LOS),Hepascore,Mayo Score,model for end-stage liver disease(MELD)score and MELD incorporated with serum sodium(MELD-Na)score].RESULTS Twenty-two AILDOS patients were followed for a median of 3.1 years(range,0.35-7.7).Fourteen were female,the median age was 46.7 years(range,17.8 to 82.1)and median Hepascore was 1(range,0.07-1).At five years post enrolment,57%of patients remained free from liver-related mortality(74%AIH-PBC,27%AIH-PSC).There was no significant difference in survival between AIH-PBC and AIH-PSC.LOS was a significant predictor of liver-related mortality(P<0.05)in patients with AIH-PBC(n=14)but not AIH-PSC(n=8).A LOS cut-point of 6 discriminated liver-related mortality in AIH-PBC patients(P=0.012,log-rank test,100%sensitivity,77.8%specificity)(Harrell's C-statistic 0.867).The MELD score,MELD-Na score and Mayo Score were not predictive of liver-related mortality in any group.CONCLUSION Survival in the rare,AILDOS is unclear.The current study supports the LOS as a predictor of liver-related mortality in AIH-PBC patients.Further trials investigating predictors of survival in AILDOS are required.展开更多
Since the new curriculum reform,labor education has gradually shed its marginalized position in the“five educations,”and the labor curriculum has become an independent course officially separated from comprehensive ...Since the new curriculum reform,labor education has gradually shed its marginalized position in the“five educations,”and the labor curriculum has become an independent course officially separated from comprehensive practical activity courses.Exploring the practical path of labor curriculum in compulsory education in China has become the primary task of labor education in China.Based on the practical situation of labor curriculum in compulsory education in China,drawing on the theory of overlapping influence domains,and from the perspective of collaborative education among family,school,and community,this paper proposes a curriculum practical path of“school-led”family-school-community collaboration and a curriculum practical path guided by“student-centered”sentiment,in order to provide references for the practice of labor curriculum in compulsory education in China.展开更多
The influences of strength coefficient K, work hardening exponent n and thickness t of the overlapping sheet on bulging process are analyzed based on hardening material model. Also, bulging experiments are carried out...The influences of strength coefficient K, work hardening exponent n and thickness t of the overlapping sheet on bulging process are analyzed based on hardening material model. Also, bulging experiments are carried out by taking the aluminum alloy LF21 as formed sheet metal, and selecting overlapping sheet with different thicknesses and material properties, by which accuracy of the above analysis result is verified in the aspects of geometric shape, thickness distribution and limit bulging height. The results show that higher strength coefficient K, larger work hardening exponent n and proper thickness of the overlapping sheet are helpful to improve the formability and forming uniformity of formed sheet metal.展开更多
A resolution method based on Gaussian-like distribution for overlapped linear sweep polarographic peaks was proposed to simultaneously detect the polymetallic components, such as Zn(Ⅱ) and Co(Ⅱ), coexisting in t...A resolution method based on Gaussian-like distribution for overlapped linear sweep polarographic peaks was proposed to simultaneously detect the polymetallic components, such as Zn(Ⅱ) and Co(Ⅱ), coexisting in the leaching solution of zinc hydrometallurgy. A Gaussian-like distribution was constructed as the sub-model of overlapped peaks by analyzing the characteristics of linear sweep polarographic curve. Then, the abscissas of each peak and trough were pinpointed through multi-resolution wavelet decomposition, the curve and its derivative curves were fitted by using nonlinear weighted least squares (NWLS). Finally, overlapped peaks were resolved into independent sub-peaks based on fitted reconstruction parameters. The experimental results show that the relative error of half-wave potential pinpointed by multi-resolution wavelet decomposition is less than 1% and the accuracy of Ip fitted by NWLS is higher than 96%. The proposed resolution method is effective for overlapped linear sweep polarographic peaks of Zn(Ⅱ) and Co(Ⅱ).展开更多
[Objective] To establish an efficient, convenient and economical method for site-directed mutagenesis. [Method] The target mutation was introduced into primers designed by DNAMAN5.0 software. Through overlap extension...[Objective] To establish an efficient, convenient and economical method for site-directed mutagenesis. [Method] The target mutation was introduced into primers designed by DNAMAN5.0 software. Through overlap extension PCR for twice obtained the mutation gene which of the full length of the recombinant Human Tissue type plasminogen activator (Reteplase). The mutation gene cloned it into pEASY- blunt simple cloning vector for sequencing. [Result] The sequencing results showed that three site mutations were fully consistent with the expected results (10~ site had been added a base-pair of A, C had been changed into G at 137~ site, G had been changed into A at 686~ site).Three site mutations were introduced by using overlap extension PCR on one-step. The overall rate of obtaining the mutant sites was 100%. Site-directed mutagenesis will clone the recombinant Human Tissue type plas- minogen activator and laid the basis for the functional study. [Conclusion] Site-directed mutagenesis was successfully implemented based on the overlap extension PCR which is an efficient, convenient and economical DNA-directed mutagenesis method.展开更多
基金supported by the National Natural Science Foundation of China(32371999)Science and Technology Program of Yulin City,China(2023-CXY-183)+1 种基金Open Project of Key Laboratory of Agricultural Equipment for Hilly and Mountainous Areas in Southeastern China(Co-construction by Ministry and Province),Ministry of Agriculture and Rural Affairs,China(QSKF2023002)National Foreign Expert Project,Ministry of Science and Technology,China(QN2022172006L,DL2022172003L).
文摘Accurate watermelon yield estimation is crucial to the agricultural value chain,as it guides the allocation of agricultural resources as well as facilitates inventory and logistics planning.The conventional method of watermelon yield estimation relies heavily onmanual labor,which is both time-consuming and labor-intensive.To address this,this work proposes an algorithmic pipeline that utilizes unmanned aerial vehicle(UAV)videos for detection and counting of watermelons.This pipeline uses You Only Look Once version 8 s(YOLOv8s)with panorama stitching and overlap partitioning,which facilitates the overall number estimation ofwatermelons in field.The watermelon detection model,based on YOLOv8s and obtained using transfer learning,achieved a detection accuracy of 99.20%,demonstrating its potential for application in yield estimation.The panorama stitching and overlap partitioning based detection and counting method uses panoramic images as input and effectively mitigates the duplications comparedwith the video tracking based detection and countingmethod.The counting accuracy reached over 96.61%,proving a promising application for yield estimation.The high accuracy demonstrates the feasibility of applying this method for overall yield estimation in large watermelon fields.
基金supported by the National Natural Science Foundation of China under Grants No.61373124
文摘Capacity reduction is a major problem faced by wireless mesh networks. An efficient way to alleviate this problem is proper channel assignment. Current end-toend channel assignment schemes usually focus on the case where channels in distinct frequency bands are assigned to mesh access and backbone, but actually backbone network and access network can use the same IEEE 802.11 technology. Besides, these channel assignment schemes only utilize orthogonal channels to perform channel assignment, and the resulting network interference dramatically degrades network performance. Moreover, Internet-oriented traffic is considered only, and peerto-peer traffic is omitted, or vice versa. The traffic type does not match the practical network. In this paper, we explore how to exploit partially overlapped channels to perform endto-end channel assignment in order to achieve effective end-to-end flow transmissions. The proposed flow-based end-to-end channel assignment schemes can conquer the limitations aforementioned. Simulations reveal that loadaware channel assignment can be applied to networks with stable traffic load, and it can achieve near-optimal performance; Traffic-irrelevant channel assignment is suitable for networks with frequent change of traffic load,and it can achieve good balance between performance and overhead. Also, partially overlapped channels' capability of improving network performance is situation-dependent, they should be used carefully.
基金Thanks to the National Natural Science Foundation of China under Grant No.61702387 for the support of the research in this paper.
文摘This paper investigates a wireless system with multi-Unmanned Aerial Vehicles(UAVs)for improving the overall throughput.In contrast to previous studies that optimize the locations of UAVs and channel assignment separately,this paper considers the two issues jointly by exploiting Partially Overlapped Channels(POCs).The optimization problem of maximizing network throughput is formulated as a non-convex and non-linear problem.In order to find a practical solution,the problem is decomposed into two subproblems,which are iteratively optimized.First,the optimal locations of UAVs are determined under a fixed channel assignment scheme by solving the mixed-integer second-order cone problem.Second,an efficient POC allocation scheme is determined via the proposed channel assignment algorithm.Simulation results show that the proposed approach not only significantly improves system throughput and service reliability compared with the cases in which only orthogonal channels and stationary UAVs are considered,but also achieves similar performance using the exhaustive search algorithm with lower time complexity.
基金the National Natural Science Foundation of China under Grant Nos 61525503 and 41603059the National Key Research and Development Project of China under Grant No 2016YFC14000701the Shenzhen Basic Research Project(JCY20160428092445411).
文摘We present our experimental ablation results for partially overlapped dual nanosecond laser beams(PO-DB)on metal and glass surfaces.Numerical simulations are performed to evaluate the crater reduction potential of the PO-DB setup.Damage probability experiments proved the collaboration of two beams within the overlap region.Bright-field and three-dimensional profile measurements verify the reduced ablation area from the proposed PODB scheme.Laser-induced plasma is generated when transparent glass is ablated.Atomic emission of Na I(~589.95nm)shows comparable signal between the PO-DB set and the traditional single laser beam set.The proposed PO-DB ablation mechanism could also be applied to femtosecond laser systems.
文摘Nowadays,wireless local area network(WLAN)has become prevalent Internet access due to its low-cost gadgets,flexible coverage and hasslefree simple wireless installation.WLAN facilitates wireless Internet services to users with mobile devices like smart phones,tablets,and laptops through deployment of multiple access points(APs)in a network field.Every AP operates on a frequency band called channel.Popular wireless standard such as IEEE 802.11n has a limited number of channels where frequency spectrum of adjacent channels overlaps partially with each other.In a crowded environment,users may experience poor Internet services due to channel collision i.e.,interference from surrounding APs that affects the performance of the WLAN system.Therefore,it becomes a challenge to maintain expected performance in a crowded environment.A mathematical model of throughput considering interferences from surrounding APs can play an important role to set up a WLAN system properly.While set up,assignment of channels considering interference can maximize network performance.In this paper,we investigate the signal propagation of APs under interference of partially overlapping channels for both bonded and non-bonded channels.Then,a throughput estimation model is proposed using difference of operating channels and received signal strength indicator(RSSI).Then,a channel assignment algorithm is introduced using proposed throughput estimation model.Finally,the efficiency of the proposal is verified by numerical experiments using simulator.The results show that the proposal selects the best channel combination of bonded and non-bonded channels that maximize the performance.
基金Sponsored by the National Natural Science Foundation of China( Grant No. 61032003)the Fundamental Research Funds for the Central Universities( Grant No. HIT. NSRIF.2012021)
文摘In this paper, according to the AR4JA codes in deep space communication, two kinds of iterative decoding including partly parallel decoding and overlapped partly parallel decoding are analyzed, and the advantages and disadvantages of them are listed. A modified overlapped partly parallel decoding that not only inherits the advantages of the two algorithms, but also overcomes the shortcomings of the two algorithms is proposed. The simulation results show that the three kinds of decoding have the same decoding performance; modified overlapped partly parallel decoding improves the iterative convergence rate and the throughput of system.
文摘In this paper, a locally non-orthogonal overlapping Yee (OY) FDTD method is proposed in order to accurately calculates the optical force on dielectric and dispersive nanoparticles. It extends our previous work to geometries with sharp corners and dispersive materials. In addition to consistently achieving the smallest errors in comparison to the standard FDTD method, the OY approach is a stable non-orthogonal FDTD method that attains second-order convergence when sharp corners are present.
文摘BACKGROUND Gastro-esophageal reflux disease(GERD)may affect the upper digestive tract;up to 20%of population in Western nations are affected by GERD.Antacids,histamine H2-receptor antagonists,and Proton Pump Inhibitors(PPIs)are considered the referring medications for GERD.Nevertheless,PPIs must be managed carefully because their use,especially chronic,could be linked with some adverse effects.An effective and safe alternative pharmacological tool for GERD is needed.After the identification of potentially new medications to flank PPIs,it is mandatory to revise and improve good clinical practices even through a consensus process.AIM To optimize diagnosis and treatment guidelines for GERD through a consensus based on Delphi method.METHODS The availability of clinical studies describing the action of the multicomponent/multitarget medication Nux vomica-Heel,subject of the consensus,is the basic prerequisite for the consensus itself.A modified Delphi process was used to reach a consensus among a panel of Italian GERD specialists on the overlapping approach PPIs/Nux vomica-Heel as a new intervention model for the management of GERD.The Voting Consensus group was composed of 49 Italian Medical Doctors with different specializations:Gastroenterology,otolaryngology,geriatrics,and general medicine.A scientific committee analyzed the literature,determined areas that required investigation(in agreement with the multiple-choice questionnaire results),and identified two topics of interest:(1)GERD disease;and(2)GERD treatment.Statements for each of these topics were then formulated and validated.The Delphi process involved two rounds of questioning submitted to the panel experts using an online platform.RESULTS According to their routinary GERD practice and current clinical evidence,the panel members provided feedback to each questionnaire statement.The experts evaluated 15 statements and reached consensus on all 15.The statements regarding the GERD disease showed high levels of agreement,with consensus ranging from 70%to 92%.The statements regarding the GERD treatment also showed very high levels of agreement,with consensus ranging from 90%to 100%.This Delphi process was able to reach consensus among physicians in relevant aspects of GERD management,such as the adoption of a new approach to treat patients with GERD based on the overlapping between PPIs and Nux vomica-Heel.The consensus was unanimous among the physicians with different specializations,underlying the uniqueness of the agreement reached to identify in the overlapping approach between PPIs and Nux vomica-Heel a new intervention model for GERD management.The results support that an effective approach to deprescribe PPIs through a progressive decalage timetable(reducing PPIs administration to as-needed use),should be considered.CONCLUSION Nux vomica-Heel appears to be a valid opportunity for GERD treatment to favor the deprescription of PPIs and to maintain low disease activity together with the symptomatology remission.
基金supported in part by the Central Government Guides Local Science and TechnologyDevelopment Funds(Grant No.YDZJSX2021A038)in part by theNational Natural Science Foundation of China under(Grant No.61806138)in part by the China University Industry-University-Research Collaborative Innovation Fund(Future Network Innovation Research and Application Project)(Grant 2021FNA04014).
文摘The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision variables.However,in practical problems,the interaction among decision variables is intricate,leading to large group sizes and suboptimal optimization effects;hence a large-scale multi-objective optimization algorithm based on weighted overlapping grouping of decision variables(MOEAWOD)is proposed in this paper.Initially,the decision variables are perturbed and categorized into convergence and diversity variables;subsequently,the convergence variables are subdivided into groups based on the interactions among different decision variables.If the size of a group surpasses the set threshold,that group undergoes a process of weighting and overlapping grouping.Specifically,the interaction strength is evaluated based on the interaction frequency and number of objectives among various decision variables.The decision variable with the highest interaction in the group is identified and disregarded,and the remaining variables are then reclassified into subgroups.Finally,the decision variable with the strongest interaction is added to each subgroup.MOEAWOD minimizes the interactivity between different groups and maximizes the interactivity of decision variables within groups,which contributed to the optimized direction of convergence and diversity exploration with different groups.MOEAWOD was subjected to testing on 18 benchmark large-scale optimization problems,and the experimental results demonstrate the effectiveness of our methods.Compared with the other algorithms,our method is still at an advantage.
基金Supported by National Natural Science Foundation of China,No.82060123National Health Commission of Guizhou Province,No.gzwjk2019-1-082.
文摘BACKGROUND Autoimmune hepatitis(AIH)and primary biliary cholangitis(PBC)are two common clinical autoimmune liver diseases,and some patients have both diseases;this feature is called AIH-PBC overlap syndrome.Autoimmune thyroid disease(AITD)is the most frequently overlapping extrahepatic autoimmune disease.Immunoglobulin(IgG)4-related disease is an autoimmune disease recognized in recent years,characterized by elevated serum IgG4 levels and infiltration of IgG4-positive plasma cells in tissues.CASE SUMMARY A 68-year-old female patient was admitted with a history of right upper quadrant pain,anorexia,and jaundice on physical examination.Laboratory examination revealed elevated liver enzymes,multiple positive autoantibodies associated with liver and thyroid disease,and imaging and biopsy suggestive of pancreatitis,hepatitis,and PBC.A diagnosis was made of a rare and complex overlap syndrome of AIH,PBC,AITD,and IgG4-related disease.Laboratory features improved on treatment with ursodeoxycholic acid,methylprednisolone,and azathioprine.CONCLUSION This case highlights the importance of screening patients with autoimmune diseases for related conditions.
基金Supported by The Guangxi TCM Suitable Technology Development and Promotion Project,No.GZSY20-20.
文摘BACKGROUND Infections by non-tuberculous mycobacteria(NTM)have become more common in recent years.Mycobacterium canariasense(M.canariasense)was first reported as an opportunistic pathogen in 2004,but there have been very few case reports since then.Nocardia is a genus of aerobic and Gram-positive bacilli,and these species are also opportunistic pathogens and in the Mycobacteriales order.Conventional methods for diagnosis of NTM are inefficient.Metagenomic next-generation sequencing(mNGS)can rapidly detect many pathogenic microorganisms,even rare species.Most NTM and Nocardia infections occur in immunocompromised patients with atypical clinical symptoms.There are no previous reports of infection by M.canariasense and Nocardia farcinica(N.farcinica),especially in immunocompetent patients.This case report describes an immunocompetent 52-year-old woman who had overlapping infections of M.canariasense,N.farcinica,and Candida parapsilosis(C.parapsilosis)based on mNGS.CASE SUMMARY A 52-year-old woman presented with a productive cough and chest pain for 2 wk,and recurrent episodes of moderate-grade fever for 1 wk.She received antibiotics for 1 wk at a local hospital,and experienced defervescence,but the productive cough and chest pain persisted.We collected samples of a lung lesion and alveolar lavage fluid for mNGS.The lung tissue was positive for M.canariasense,N.farcinica,and C.parapsilosis,and the alveolar lavage fluid was positive for M.canariasense.The diagnosis was pneumonia,and application of appropriate antibiotic therapy cured the patient.CONCLUSION Etiological diagnosis is critical for patients with infectious diseases.mNGS can identify rare and novel pathogens,and does not require a priori knowledge.
基金This work was supported by the National Science Fund for Distinguished Young Scholars(62325104).
文摘The quality of synthetic aperture radar(SAR)image degrades in the case of multiple imaging projection planes(IPPs)and multiple overlapping ship targets,and then the performance of target classification and recognition can be influenced.For addressing this issue,a method for extracting ship targets with overlaps via the expectation maximization(EM)algorithm is pro-posed.First,the scatterers of ship targets are obtained via the target detection technique.Then,the EM algorithm is applied to extract the scatterers of a single ship target with a single IPP.Afterwards,a novel image amplitude estimation approach is pro-posed,with which the radar image of a single target with a sin-gle IPP can be generated.The proposed method can accom-plish IPP selection and targets separation in the image domain,which can improve the image quality and reserve the target information most possibly.Results of simulated and real mea-sured data demonstrate the effectiveness of the proposed method.
文摘BACKGROUND Survival in patients with autoimmune liver disease overlap syndromes(AILDOS)compared to those with single autoimmune liver disease is unclear.AIM To investigate the survival of patients with AILDOS and assess the accuracy of non-invasive serum models for predicting liver-related death.METHODS Patients with AILDOS were defined as either autoimmune hepatitis and primary biliary cholangitis overlap(AIH-PBC)or autoimmune hepatitis and primary sclerosing cholangitis overlap(AIH-PSC)and were identified from three tertiary centres for this cohort study.Liver-related death or transplantation(liver-related mortality)was determined using a population-based data linkage system.Prognostic scores for liver-related death were compared for accuracy[including liver outcome score(LOS),Hepascore,Mayo Score,model for end-stage liver disease(MELD)score and MELD incorporated with serum sodium(MELD-Na)score].RESULTS Twenty-two AILDOS patients were followed for a median of 3.1 years(range,0.35-7.7).Fourteen were female,the median age was 46.7 years(range,17.8 to 82.1)and median Hepascore was 1(range,0.07-1).At five years post enrolment,57%of patients remained free from liver-related mortality(74%AIH-PBC,27%AIH-PSC).There was no significant difference in survival between AIH-PBC and AIH-PSC.LOS was a significant predictor of liver-related mortality(P<0.05)in patients with AIH-PBC(n=14)but not AIH-PSC(n=8).A LOS cut-point of 6 discriminated liver-related mortality in AIH-PBC patients(P=0.012,log-rank test,100%sensitivity,77.8%specificity)(Harrell's C-statistic 0.867).The MELD score,MELD-Na score and Mayo Score were not predictive of liver-related mortality in any group.CONCLUSION Survival in the rare,AILDOS is unclear.The current study supports the LOS as a predictor of liver-related mortality in AIH-PBC patients.Further trials investigating predictors of survival in AILDOS are required.
文摘Since the new curriculum reform,labor education has gradually shed its marginalized position in the“five educations,”and the labor curriculum has become an independent course officially separated from comprehensive practical activity courses.Exploring the practical path of labor curriculum in compulsory education in China has become the primary task of labor education in China.Based on the practical situation of labor curriculum in compulsory education in China,drawing on the theory of overlapping influence domains,and from the perspective of collaborative education among family,school,and community,this paper proposes a curriculum practical path of“school-led”family-school-community collaboration and a curriculum practical path guided by“student-centered”sentiment,in order to provide references for the practice of labor curriculum in compulsory education in China.
基金Project(51205260)supported by the National Natural Science Foundation of ChinaProject(L2012046)supported by the Liaoning Provincial Committee of Education,China
文摘The influences of strength coefficient K, work hardening exponent n and thickness t of the overlapping sheet on bulging process are analyzed based on hardening material model. Also, bulging experiments are carried out by taking the aluminum alloy LF21 as formed sheet metal, and selecting overlapping sheet with different thicknesses and material properties, by which accuracy of the above analysis result is verified in the aspects of geometric shape, thickness distribution and limit bulging height. The results show that higher strength coefficient K, larger work hardening exponent n and proper thickness of the overlapping sheet are helpful to improve the formability and forming uniformity of formed sheet metal.
基金Project(2012BAF03B05)supported by the National Key Technology R&D Program of ChinaProject(61025015)supported by the National Natural Science Foundation for Distinguished Young Scholars of China+1 种基金Project(61273185)supported by the National Natural Science Foundation of ChinaProject(2012CK4018)supported by the Science and Technology Project of Hunan Province,China
文摘A resolution method based on Gaussian-like distribution for overlapped linear sweep polarographic peaks was proposed to simultaneously detect the polymetallic components, such as Zn(Ⅱ) and Co(Ⅱ), coexisting in the leaching solution of zinc hydrometallurgy. A Gaussian-like distribution was constructed as the sub-model of overlapped peaks by analyzing the characteristics of linear sweep polarographic curve. Then, the abscissas of each peak and trough were pinpointed through multi-resolution wavelet decomposition, the curve and its derivative curves were fitted by using nonlinear weighted least squares (NWLS). Finally, overlapped peaks were resolved into independent sub-peaks based on fitted reconstruction parameters. The experimental results show that the relative error of half-wave potential pinpointed by multi-resolution wavelet decomposition is less than 1% and the accuracy of Ip fitted by NWLS is higher than 96%. The proposed resolution method is effective for overlapped linear sweep polarographic peaks of Zn(Ⅱ) and Co(Ⅱ).
基金Supported by National Natural Science Foundation of China(31160032)~~
文摘[Objective] To establish an efficient, convenient and economical method for site-directed mutagenesis. [Method] The target mutation was introduced into primers designed by DNAMAN5.0 software. Through overlap extension PCR for twice obtained the mutation gene which of the full length of the recombinant Human Tissue type plasminogen activator (Reteplase). The mutation gene cloned it into pEASY- blunt simple cloning vector for sequencing. [Result] The sequencing results showed that three site mutations were fully consistent with the expected results (10~ site had been added a base-pair of A, C had been changed into G at 137~ site, G had been changed into A at 686~ site).Three site mutations were introduced by using overlap extension PCR on one-step. The overall rate of obtaining the mutant sites was 100%. Site-directed mutagenesis will clone the recombinant Human Tissue type plas- minogen activator and laid the basis for the functional study. [Conclusion] Site-directed mutagenesis was successfully implemented based on the overlap extension PCR which is an efficient, convenient and economical DNA-directed mutagenesis method.