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Esophageal motility in patients with sliding hiatal hernia with reflux esophagitis 被引量:11
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作者 YE Ping LI Zhao-shen +3 位作者 XU Guo-ming ZOU Duo-wu XU Xiao-rong LU Ren-hua 《Chinese Medical Journal》 SCIE CAS CSCD 2008年第10期898-903,共6页
Background Patients with sliding hiatus hernia (HH) and reflux esophagitis (RE) usually suffer from esophageal dysmotility. The aim of the present study was to investigate the role of acid reflux and duodenal gast... Background Patients with sliding hiatus hernia (HH) and reflux esophagitis (RE) usually suffer from esophageal dysmotility. The aim of the present study was to investigate the role of acid reflux and duodenal gastroesophageal reflux (DGER), esophageal manometry, and esophageal dysmotility by applying the barium meal examination. Methods RE with HH was initially diagnosed using the reflux disease questionnaire, and was further confirmed by a barium meal examination and an endoscopy. The radiographic technique was used to test for spasms, strictures, and the coarseness of the mucosa, also was to study the types of reflux and clearance. Then, the esophageal manometry, the esophageal 24-hour pH, and the bilirubin monitoring were observed. Results Fifty-five patients were diagnosed as HH combined with RE and divided into two groups according to the severity of their esophagitis: group HH1 (grades A and B) and group HH2 (grades C and D). The barium meal examination revealed that the mucosa was either granular or nodular in all cases. The dump reflux and delayed clearance were more significant in patients in the HH2 group than those in the HH1 group (P 〈0.05). The percentages of total, supine, and upright acid exposure time were greater in patients with HH than those in the control group (P 〈0.01), but the differences between the HH1 and the HH2 groups were not significant. Lower esophageal sphictor pressure (LESP) was lower in the HH group than in the control group (P 〈0.05). Three DGER parameters: the percentage of time with absorbance greater than 0.14, the number of bile reflux episodes, the number of bile refluxes lasting longer than 5 minutes were (28.43±23.34), (40.57±31.30), and (15.15±8.72), respectively in the HH2 group; these statistics were significantly higher than those for the HH1 (P 〈0.05). The frequency and amplitude of peristalsis were all lower in HH patients than in the control (P 〈0.05). Of all the patients, 54.3% (30 of 55) with acid reflux and DGER simultaneously in the HH group exhibited refluxes of barium from the stomach to the esophagus in the recumbent position, and 29.4% (5 in 17) with delayed clearance in the HH group were correlated with esophageal body peristalses. The result was that the frequency and amplitude of peristalsis were less and the duration of esophageal peristalsis was longer than those of control group. Conclusions Esophageal dysmotility may play an important role in the severity of RE combined with HH. Esophageal motility results on a barium examination may coincide with esophageal manometry, 24-hour pH, and bilirubin monitoring in the RE and HH, but the radiologic method was the simplest to apply. 展开更多
关键词 barium meal examination ph and bilirubin monitoring MANOMETRY duodengastroesophageal reflux reflux esophagitis
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