<b>Background: </b>Though painless abortion is a safe, effective and excellent method of artificial abortion, intravenous anesthesia cannot effectively expand the cervix. Hard and tight cervix often affect...<b>Background: </b>Though painless abortion is a safe, effective and excellent method of artificial abortion, intravenous anesthesia cannot effectively expand the cervix. Hard and tight cervix often affects the operation and easily inducesabortion complications. Misoprostol can induce uterine contraction and soften the cervix. <b>Objective:</b> To investigate the clinical effect of misoprostol on abortion before and after painless induced abortion. <b>Methods:</b> 600 case pregnant women were divided into three groups: A, B and C, 200 case in each group. All patients were anesthetized. In group A, misoprostol 0.2 ug was placed in the posterior fornix of vagina 2 hours before the operation of induced abortion;in group B, misoprostol 0.2 ug was not only placed in the posterior fornix of vagina 2 hours before the operation of induced abortion but also taken orally 2 hours and 6 hours after the operation;in group C, misoprostol was not used before and after the operation. The operation time, intraoperative bleeding volume, postoperative bleeding, the percentage of cervical relaxation and the rate of incomplete abortion among the three groups were compared. <b>Results:</b> Compared with group A and group B, the operation time of group C was longer and the amount of bleeding was more (P < 0.05), but there was no significant difference between group A and group B (P > 0.05). The duration of bleeding in group B was less than that in group A (P < 0.05). The percentage of cervical relaxation in group A and B was higher than that in group C (P < 0.05). The rate of incomplete abortion in group B < group A < group C (P < 0.05), and there was no residual uterine cavity in group B. <b>Conclusion:</b> The use of misoprostol before and after painless induced abortion can not only shorten the time of operation, reduce intraoperative and postoperative vaginal bleeding, but also has not incurred incomplete abortion(primary outcome).展开更多
Objective: This project is to analyze and evaluate the efYect of the painless technique in the visual induced abortion. Methods: 300 pregnant women who needed induced abortion and had no contraindication were selected...Objective: This project is to analyze and evaluate the efYect of the painless technique in the visual induced abortion. Methods: 300 pregnant women who needed induced abortion and had no contraindication were selected as the research objects. Under the condition of the informed consent of the pregnant women, they were divided into two groups according to the different methods of the induced abortion. 150 cases in the observation group were treated with the painless technique for visual abortion, and 150 cases in the control group were treated with the painless technique for the blind curettage. Relevant surgical indicators and complications were compared between the two groups. Results: The operation time, the vaginal bleeding time, the induced abortion syndrome, the uterine aspiration incompleteness, and the postoperative infection in the observation group were significantly lower than those in the control group. The difference between the two groups was significant (P 0.05), with the statistical significance. The incidence of complications in the observation group (8.33%) was significantly lower than that in the control group (37.50%). The difference between the two groups was significant (P 0.05), with the statistical significance. Conclusion: The visual induced abortion with the painless technique is of great value in the outpatient induced abortion, and it is worth adopting and applying.展开更多
目的采用系统评价地佐辛和芬太尼分别复合丙泊酚用于无痛人流术的效果和安全性。方法电子检索Cochrane图书馆、Pubmed、中国知网、万方数据库、维普资讯网中从建库到2015年1月发表的关于地佐辛和芬太尼分别复合丙泊酚用于无痛人流的随...目的采用系统评价地佐辛和芬太尼分别复合丙泊酚用于无痛人流术的效果和安全性。方法电子检索Cochrane图书馆、Pubmed、中国知网、万方数据库、维普资讯网中从建库到2015年1月发表的关于地佐辛和芬太尼分别复合丙泊酚用于无痛人流的随机对照试验,根据Cochrane系统评价的方法评价纳入研究的质量和提取资料,采用Rev Man 5.2软件进行统计分析。结果共纳入15篇临床随机对照试验共计1262例患者。分析结果显示:1有效性:与芬太尼复合丙泊酚组比较,地佐辛复合组能够显著减少丙泊酚的总用量(MD=-29.36,95%CI-41.60^-17.12,P=0.0100),缩短术后苏醒时间(MD=-1.62,95%CI-2.06^-1.18,P<0.0001);2不良反应:术后地佐辛复合丙泊酚组恶心呕吐、呼吸抑制、头晕的发生率均低于芬太尼组复合丙泊酚组,差异有统计学意义(OR=0.28、0.20、0.43,95%CI分别为0.17~0.46、0.13~0.31、0.26~0.73),术中体动的发生率两组比较,差异无统计学意义(OR=0.64,95%CI 0.40~1.04,P=0.07)。结论现有临床证据表明,地佐辛复合丙泊酚与芬太尼复合丙泊酚用于无痛人流术相比,可以缩短苏醒时间,减少丙泊酚的总用量及不良反应的发生,其效果更好、安全性更高。展开更多
文摘<b>Background: </b>Though painless abortion is a safe, effective and excellent method of artificial abortion, intravenous anesthesia cannot effectively expand the cervix. Hard and tight cervix often affects the operation and easily inducesabortion complications. Misoprostol can induce uterine contraction and soften the cervix. <b>Objective:</b> To investigate the clinical effect of misoprostol on abortion before and after painless induced abortion. <b>Methods:</b> 600 case pregnant women were divided into three groups: A, B and C, 200 case in each group. All patients were anesthetized. In group A, misoprostol 0.2 ug was placed in the posterior fornix of vagina 2 hours before the operation of induced abortion;in group B, misoprostol 0.2 ug was not only placed in the posterior fornix of vagina 2 hours before the operation of induced abortion but also taken orally 2 hours and 6 hours after the operation;in group C, misoprostol was not used before and after the operation. The operation time, intraoperative bleeding volume, postoperative bleeding, the percentage of cervical relaxation and the rate of incomplete abortion among the three groups were compared. <b>Results:</b> Compared with group A and group B, the operation time of group C was longer and the amount of bleeding was more (P < 0.05), but there was no significant difference between group A and group B (P > 0.05). The duration of bleeding in group B was less than that in group A (P < 0.05). The percentage of cervical relaxation in group A and B was higher than that in group C (P < 0.05). The rate of incomplete abortion in group B < group A < group C (P < 0.05), and there was no residual uterine cavity in group B. <b>Conclusion:</b> The use of misoprostol before and after painless induced abortion can not only shorten the time of operation, reduce intraoperative and postoperative vaginal bleeding, but also has not incurred incomplete abortion(primary outcome).
文摘Objective: This project is to analyze and evaluate the efYect of the painless technique in the visual induced abortion. Methods: 300 pregnant women who needed induced abortion and had no contraindication were selected as the research objects. Under the condition of the informed consent of the pregnant women, they were divided into two groups according to the different methods of the induced abortion. 150 cases in the observation group were treated with the painless technique for visual abortion, and 150 cases in the control group were treated with the painless technique for the blind curettage. Relevant surgical indicators and complications were compared between the two groups. Results: The operation time, the vaginal bleeding time, the induced abortion syndrome, the uterine aspiration incompleteness, and the postoperative infection in the observation group were significantly lower than those in the control group. The difference between the two groups was significant (P 0.05), with the statistical significance. The incidence of complications in the observation group (8.33%) was significantly lower than that in the control group (37.50%). The difference between the two groups was significant (P 0.05), with the statistical significance. Conclusion: The visual induced abortion with the painless technique is of great value in the outpatient induced abortion, and it is worth adopting and applying.
文摘目的采用系统评价地佐辛和芬太尼分别复合丙泊酚用于无痛人流术的效果和安全性。方法电子检索Cochrane图书馆、Pubmed、中国知网、万方数据库、维普资讯网中从建库到2015年1月发表的关于地佐辛和芬太尼分别复合丙泊酚用于无痛人流的随机对照试验,根据Cochrane系统评价的方法评价纳入研究的质量和提取资料,采用Rev Man 5.2软件进行统计分析。结果共纳入15篇临床随机对照试验共计1262例患者。分析结果显示:1有效性:与芬太尼复合丙泊酚组比较,地佐辛复合组能够显著减少丙泊酚的总用量(MD=-29.36,95%CI-41.60^-17.12,P=0.0100),缩短术后苏醒时间(MD=-1.62,95%CI-2.06^-1.18,P<0.0001);2不良反应:术后地佐辛复合丙泊酚组恶心呕吐、呼吸抑制、头晕的发生率均低于芬太尼组复合丙泊酚组,差异有统计学意义(OR=0.28、0.20、0.43,95%CI分别为0.17~0.46、0.13~0.31、0.26~0.73),术中体动的发生率两组比较,差异无统计学意义(OR=0.64,95%CI 0.40~1.04,P=0.07)。结论现有临床证据表明,地佐辛复合丙泊酚与芬太尼复合丙泊酚用于无痛人流术相比,可以缩短苏醒时间,减少丙泊酚的总用量及不良反应的发生,其效果更好、安全性更高。