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抗生素后效应的研究进展及其临床意义 被引量:13
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作者 许静 赵真玲 吴学晋 《中国临床药学杂志》 CAS 1999年第4期255-258,共4页
抗生素后效应(post-antibiotic effect,PAE)系指细菌与抗生素短暂接触,当药物浓度下降;低于最低抑菌浓度(MIC)或清除后,细菌的生长仍受到持续抑制的效应.从微观角度讲,PAE是指抗生素与细菌短暂接触后,持续抑制细胞分裂,使生存数目减少.7... 抗生素后效应(post-antibiotic effect,PAE)系指细菌与抗生素短暂接触,当药物浓度下降;低于最低抑菌浓度(MIC)或清除后,细菌的生长仍受到持续抑制的效应.从微观角度讲,PAE是指抗生素与细菌短暂接触后,持续抑制细胞分裂,使生存数目减少.70年代中期Mcdonald和Craig等提出了抗生素后效应这一理论.近年来,国内外对PAE的研究愈渐深入和广泛.PAE作为重要的药效学参数,对于指导临床合理应用抗生素具有重要的实际意义.1 PAE的机制抗生素产生PAE的机理目前尚不明确. 展开更多
关键词 抗生素后效应 PAE PALE PA-SME EDP3
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抗结核药后效应
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作者 张天民 《结核病与胸部肿瘤》 2003年第3期244-246,共3页
关键词 抗结核药 抗生素后效应 PAE 抗生素后亚抑菌浓度效应 MIC 抗生素后促白细胞效应 PALE
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AlN隔离层生长时间对AlGaN/AlN/GaN HEMT材料电学性能的影响
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作者 钟林健 邢艳辉 +5 位作者 韩军 陈翔 朱启发 范亚明 邓旭光 张宝顺 《发光学报》 EI CAS CSCD 北大核心 2014年第7期830-834,共5页
利用金属有机化学气相沉积(MOCVD)设备,在蓝宝石(0001)面上外延不同生长时间AlN隔离层的AlxGa1-xN/AlN/GaN结构的高电子迁移率的晶体管(HEMT),研究了AlN隔离层厚度对HEMT材料电学性能的影响。研究发现采用脉冲法外延(PALE)技术生长AlN... 利用金属有机化学气相沉积(MOCVD)设备,在蓝宝石(0001)面上外延不同生长时间AlN隔离层的AlxGa1-xN/AlN/GaN结构的高电子迁移率的晶体管(HEMT),研究了AlN隔离层厚度对HEMT材料电学性能的影响。研究发现采用脉冲法外延(PALE)技术生长AlN隔离层的时间为12 s(1 nm左右)时,HEMT材料的方块电阻最小,电子迁移率为1 500 cm2·V-1·s-1,二维电子气(2DEG)浓度为1.16×1013cm-2。AFM测试结果表明,一定厚度范围内的AlN隔离层并不会对材料的表面形貌产生重大的影响。HRXRD测试结果表明,AlGaN/AlN/GaN具有好的异质结界面。 展开更多
关键词 AlN厚度 PALE MOCVD HEMT 电学性能
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Identification and Fine Mapping of a Gene Related to Pale Green Leaf Phenotype near the Centromere Region in Rice(Oryza sativa) 被引量:11
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作者 ZHU Li LiuWenzhen WU Chao LUAN Wei jiang Fu Ya ping Hu Guo cheng SI Hua min SUN Zong xiu 《Rice science》 SCIE 2007年第3期172-180,共9页
A thermo-insensitive pale green leaf mutant (pgl2) was isolated from T-DNA inserted transgenic lines of rice (Oryza sativa L. subsp, japonica cv. Nipponbare). Genetic analysis indicated that the phenotype was caus... A thermo-insensitive pale green leaf mutant (pgl2) was isolated from T-DNA inserted transgenic lines of rice (Oryza sativa L. subsp, japonica cv. Nipponbare). Genetic analysis indicated that the phenotype was caused by a recessive mutation in a single nuclear-encoded gene. To map the PGL2gene, an F2 population was constructed by crossing the mutant with Longtefu (Oryza sativa L. subsp, indica). The PGL2 locus was roughly linked to SSR marker RM331 on chromosome 8. To finely map the gene, 14 new InDel markers were developed around the marker, and PGL2 was further mapped to a 2.37 Mb centromeric region. Analysis on chlorophyll contents of leaves showed that there was no obvious difference between the mutant and the wild type in total chlorophyll (Chl) content, while the ratio of Chl a / Chl b in the mutant was only about 1, which was distinctly lower than that in the wild type, suggesting that the PGL2 gene was related to the conversion between Chl a and Chl b. Moreover, the method of primer design around the centromeric region was discussed, which would provide insight into fine mapping of the functional genes in plant centromeres. 展开更多
关键词 CENTROMERE GENE fine mapping pale green leaf mutant chlorophyll a chlorophyll b RICE
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PALEOGENE(?) DEPOSYSTEMS AND BASIN EVOLUTION IN THE EASTERN TIBETAN PLATEAU: NANGQIAN AND XIALAXIU BASINS 被引量:5
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作者 Brian K. Horton 1,3 , Zhou Jiangyu 2, Matt S. Spurlin 1, An Yin 1, Wang Jianghai 2 (1 Department of Earth and Space Sciences, University of California, Los Angeles,CA 90095\|1567 USA 2 Guangzhou Institute of Geochemistry, Chinese Academy of Sc 《地学前缘》 EI CAS CSCD 2000年第S1期282-283,共2页
Paleogene sedimentary basins exposed across much of the central and eastern Tibetan Plateau may record the early history of plateau uplift related to the Indo\|Asian collision. We conducted sedimentological and strati... Paleogene sedimentary basins exposed across much of the central and eastern Tibetan Plateau may record the early history of plateau uplift related to the Indo\|Asian collision. We conducted sedimentological and stratigraphic investigations in the northeastern Qiangtang terrane, eastern Tibetan Plateau. Our results indicate development of several nonmarine basins during Paleogene(?) time, probably synchronous with northeast\|southwest contractional deformation. The Nangqian and Xialaxiu basins (96°~97°E, 32°~33°N) are composed of 500~ 20000m thick successions of primarily clastic sediment indicative of lacustrine and alluvial\|fan depositional processes. Paleocurrent measurements and sediment compositional data indicate local sediment source areas composed of Carboniferous\|Triassic carbonate and sandstone and minor Tertiary volcanic rocks. The large variability of provenance and facies types suggest that each basin evolved independently, as opposed to regional development of a single integrated basin which was partitioned by later deformation. 展开更多
关键词 ALLUVIAL fan basin contraction deposystem LACUSTRINE PALE ogene QIANGTANG Tibet
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江西省设施农业用地使用效率度量分析 被引量:1
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作者 黄伟 邸思霖 周应恒 《南方农业》 2022年第21期5-13,共9页
发展设施农业关系到我国的农业现代化和乡村振兴,各级政府一直关注设施农业用地的合理使用。针对以往文献提出的农业用地使用效率度量方法不适用于设施农业用地这个问题,通过农业生产模型推导出设施农业用地的使用效率指标——PALE指标... 发展设施农业关系到我国的农业现代化和乡村振兴,各级政府一直关注设施农业用地的合理使用。针对以往文献提出的农业用地使用效率度量方法不适用于设施农业用地这个问题,通过农业生产模型推导出设施农业用地的使用效率指标——PALE指标,提出了一套假设检验用于考查某个地区的设施农业用地的使用效率情况及其变化原因。用时变双重差分模型(Time-varying DID model)和江西省的数据,度量了江西省设施农业用地的PALE指标,并对相关假设进行了检验,结果发现江西省设施农业用地的使用情况较好,需要注意提高设施农业用地的使用效率。 展开更多
关键词 设施农业用地 土地使用效率 农业生产函数 Time-varying DID分析 PALE指标 江西省
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Who Invented Whom?——Picking up Cues in Pale Fire
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作者 颜希 刘诗永 +1 位作者 白丹 蒲芸 《海外英语》 2021年第10期220-221,229,共3页
Reading Nabokov's Pale Fire is a magical discovery of artistry. Years elapsed, the"who invented whom"question remains an enigma. Through expounding four current interpretations and tracing the relationsh... Reading Nabokov's Pale Fire is a magical discovery of artistry. Years elapsed, the"who invented whom"question remains an enigma. Through expounding four current interpretations and tracing the relationship among the major characters, the real author behind this intriguing work—Nabokov is reshaped. Meanwhile, several fundamental ideas prevalent in his literary creation are discussed, casting some light on the philosophy behind his literary creation. 展开更多
关键词 NABOKOV Pale Fire POEM Kinbote SHADE Gradus Botkin
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On the Dual “Defamiliarization” Method and Its Source in Pale Fire
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作者 ZHAO Hong-jun GULIDIYAER Dilimulati 《Journal of Literature and Art Studies》 2021年第3期158-160,共3页
Nabokov believes that “art is a method by which the writer is able to cause a special aesthetic experience among thereader”;language, structure, style and other means of expression are always more important than the... Nabokov believes that “art is a method by which the writer is able to cause a special aesthetic experience among thereader”;language, structure, style and other means of expression are always more important than the plot of thework. We can find a vivid embodiment of this creation view in Pale Fire. Because of the method“defamiliarization”, the aesthetics of the whole novel is expressed in three key steps: the introduction of poeticambiguity on Shade’s poem;an explanation of poetic ambiguity by means of Kinbote’s commentary;regenarationof ambiguity through the suspension of Kinbote’s commentary from Shade’s poetic language. The artistic theme ofambiguity is a manifestation of the author’s hidden feelings for the homeland. Nabokov, as an expatriate Russianwriter, is experiencing not only a deep relationship with his homeland, but also a sense of bitterness from being inexile. His impression and memories of hometown beacame the inspiration for creation. 展开更多
关键词 Pale Fire NABOKOV “defamiliarization” HOMELAND
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Etsuko’s Pursuit of Identity:An Interpretation of A Pale View of Hills from the Perspective of Spatial Criticism
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作者 HU Sheng-hao 《Journal of Literature and Art Studies》 2020年第10期873-879,共7页
On the basis of Etsuko’s memory,A Pale View of Hills,a masterpiece of Kazuo Ishiguro,narrates Etsuko’s life experiences and her identity construction.The paper analyses the novel from the perspective of spatial crit... On the basis of Etsuko’s memory,A Pale View of Hills,a masterpiece of Kazuo Ishiguro,narrates Etsuko’s life experiences and her identity construction.The paper analyses the novel from the perspective of spatial criticism proposed by Edward Soja and explores the three-dimensional spaces constructed in the novel in order to explore Etsuko’s attempts to leave the marginal space and analyse her pursuit of identity.The paper comes to the conclusion that by constructing Thirdspace open to all cultures,Etsuko eliminates the dichotomy between Firstspace and Secondspace and embraces her hybrid identity. 展开更多
关键词 Kazuo Ishiguro A Pale View of Hills spatial criticism
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Activating a Protocol for Prevention, Management and Follow up of Dermal Filler Injection Related Vascular Occlusion (A Clinical Audit)
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作者 Ahmed Abdelmoez Alsayed 《Modern Plastic Surgery》 2020年第4期120-126,共7页
With the increased demand for dermal filler injections, more complications and adverse events are reported. Vascular occlusion is one of the most serious complications. The need urges to adopt a powerful protocol to m... With the increased demand for dermal filler injections, more complications and adverse events are reported. Vascular occlusion is one of the most serious complications. The need urges to adopt a powerful protocol to manage such cases. The private practice I am working for has six branches in the middle east. I tried to investigate if there were any vascular occlusion incidences through the last three years. Four cases without sufficient details were found. A protocol was adopted from a scientific reference to deal with similar cases properly. A re-audit was done after six months to test the efficiency of the suggested protocol. 展开更多
关键词 DERMAL FILLER VASCULAR OCCLUSION Code: Pale
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Interpretation of the Poem‘Pale Fire'in Vladimir Nabokov's Pale Fire
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作者 霍甜甜 《海外英语》 2014年第4X期162-164,共3页
With its uttermost innovate form and its puzzle content, Pale Fire has sustained Nabokov the most intensive scholarly attention ever since its publication. Despite a great deal of criticism on the novel Pale Fire the ... With its uttermost innovate form and its puzzle content, Pale Fire has sustained Nabokov the most intensive scholarly attention ever since its publication. Despite a great deal of criticism on the novel Pale Fire the poem Pale Fire within it has been neglected. This essay commits to analyze this poem from four perspectives, namely its symmetrical structure, the counterpoint of the poem, its parody and intertextuality and its meta-poetic element. By doing the detailed examination this essay proves that this 999 line poem embodies the significant themes of this novel, which are the counterpoint and"a Web of Sense". 展开更多
关键词 Vladimir NABOKOV PALE FIRE The POEM PALE FIRE
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Prevalence of Iron Deficiency Anaemia in School and College Going Students of District Shaheed Benazirabad Sindh Province, Pakistan
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作者 Niaz Hussain Jamali Hidayatullah Mahesar Muhammad Aqeel Bhutto 《Open Journal of Blood Diseases》 2016年第4期67-78,共12页
The present study aimed to estimate the occurrence of Iron Deficiency anemia (IDA) in school and college going students (aged 11 - 18 years). Anemia is the most public health problem in school age children. It has a w... The present study aimed to estimate the occurrence of Iron Deficiency anemia (IDA) in school and college going students (aged 11 - 18 years). Anemia is the most public health problem in school age children. It has a wide range of adverse results involving, poor cognitive performance, poor development of infants, preschool and school-aged children. Anemia also causes the impairment of physical capacity, work performance of adolescents and adults, reduction in immune competence and increased morbidity from infections in all age groups. Our study based on 1686 volunteers was randomly selected from different Government High schools and colleges. A Questionnaire was utilized for data collection. BMI was also calculated by dividing weight in kg by the square of height in meters. Hemoglobin (Hb), Hematocrite (Hct), Mean Corpuscular volume (MCV), Mean Corpuscular hemoglobin concentration (MCHC), white blood cell (WBC) and red blood cell was examined using Sysmex kx-21N hemoglobin auto analyzer (Hedwin, 2008). The total percentage of anaemic students (43.1%) and non-anaemic (56.9%) were observed in district Shaheed Benazirabad. The mean Hb level of anaemic students (11.1 ± 4.94) was observed. In males (12.7%) and females (30.4%) anemic was observed. The prevalence of anemia high (16.2%) was observed in the age of 14 - 16 years. The majority of anemic patients (30.2%) belonged to low income group. Area wise prevalence, in rural areas 27.8% and urban areas 15.3% volunteers anaemic was observed. Taluka wise occurrence of anaemia in taluka Sakrand was (14.6%), in taluka Kazi Ahmed (15.0%), in taluka Daur (8.0%) and in taluka Nawabshah was (5.5%). Clinically signs and symptoms showed, pale skin 57.7% and weakness 42.3% were observed in school children. 展开更多
关键词 Iron Deficiency Anaemia (IDA) Haemglobin (Hb) Red Blood Cell (RBC) White Blood Cell (WBC) Hematocrit (Hct) Body Mass Index (BMI) School Children Pale Skin
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Paleogeothermal gradient and geologic thermal history of the Turpan-Hami Basin, Xinjiang 被引量:1
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作者 柳益群 吴涛 +1 位作者 崔旱云 冯乔 《Science China Earth Sciences》 SCIE EI CAS 1998年第1期62-68,共7页
Synthetical research has been done on the geological thermal history of the Turpan\|Hami Basin by using vitrinite reflectance, fluid inclusion geothermometry and fission track. The geotemperature of the Turpan\|Hami B... Synthetical research has been done on the geological thermal history of the Turpan\|Hami Basin by using vitrinite reflectance, fluid inclusion geothermometry and fission track. The geotemperature of the Turpan\|Hami Basin has the character that suggests higher temperature in the past, in the east and south of the basin, and in the areas of large\|fracture, and lower temperature in the present day and in the west and north of the basin. This feature is controlled by the difference of burial depth of basement and heat flow values, which made Permian source rock mature in the late Triassic and Jurassic source rock mature at the end of Jurassic and the early Tertiary. 展开更多
关键词 Turpan\|Hami Basin VITRINITE reflectance fluid inclusion GEOTHERMOMETRY APATITE FISSION track PALE ogeothermal gradient.
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车前(Blond psyllium) 被引量:1
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《国外医药(植物药分册)》 2007年第6期277-278,共2页
关键词 PSYLLIUM 车前 PALE
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PALEONTOLOGY
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《Abstracts of Chinese Geological Literature》 2014年第4期99-106,共8页
20142263Lü Shaojun(Geological Survey of Jiangxi Province,Nanchang 330030,China)Early-Middle Permian Biostratigraphical Characteristics in Qiangduo Area,Tibet(Resources Survey&Environment,ISSN1671-4814,CN32-16... 20142263Lü Shaojun(Geological Survey of Jiangxi Province,Nanchang 330030,China)Early-Middle Permian Biostratigraphical Characteristics in Qiangduo Area,Tibet(Resources Survey&Environment,ISSN1671-4814,CN32-1640/N,34(4),2013,p.221-227,2illus.,2tables,22refs.)Key words:biostratigraphy,Lower Permian,Middle Permian。 展开更多
关键词 PERMIAN Nanchang Tibet JIANGXI MIDDLE NANJING PALE
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PETROLOGY IGNEOUS PETROLOGY
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《Abstracts of Chinese Geological Literature》 2007年第1期53-66,共14页
20070176 Chai Fengmei (State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China); Zhang Zhaochong Lamprophyre or Lamproite Dyke in the SW Tarim Block?-... 20070176 Chai Fengmei (State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing 100083, China); Zhang Zhaochong Lamprophyre or Lamproite Dyke in the SW Tarim Block?--Discussion on the Petrogenesis of These Rocks and Their Source Region (Journal of China University of Geosciences, ISSN1002-0705, CN42-1279/P, 17(1), 2006, p.13-24, 9 illus., 3 tables, 44 refs.) Key words: Lamprophyres, Tarim 展开更多
关键词 VOLCANIC MAGMATIC MANTLE dating tables ZIRCON PALE
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PALEONTOLOGY (2)PALEOBOTANY
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《Abstracts of Chinese Geological Literature》 2007年第2期113-113,共1页
20071213 Guo Xianpu(Institute of Geology, Chinese Academy of Geological Science,Bei- jing 100037);Wang Naiwen Palaeontolog- ical Proof of the Naij Tal Group-Complex as Melange Aggregation in the Eastern Kun- lun Oroge... 20071213 Guo Xianpu(Institute of Geology, Chinese Academy of Geological Science,Bei- jing 100037);Wang Naiwen Palaeontolog- ical Proof of the Naij Tal Group-Complex as Melange Aggregation in the Eastern Kun- lun Orogenic Belt and Its Geologic Signifi- cance(Geological Review,ISSN0371-5736, CN11-1952/P,52(3),2006,p.289-294, 2 illus.,2 plates,19 refs.) 展开更多
关键词 Eastern GENERA STRATA SEDIMENTARY PALEOBOTANY PALE
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PALEOBOTANY
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《Abstracts of Chinese Geological Literature》 2011年第4期108-108,共1页
20112464Quan Cheng(Key Lab.for Evolution of Past Life and Environment in Northeast Asia,MOE,Jilin University,Changchun 130026,China);Zhou Zhiyan Occurrence of Oligocene Ginkgo Megafossils
关键词 GINKGO Changchun NORTHEAST Jilin Heilongjiang PALE
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