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双表型鼻腔鼻窦肉瘤1例
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作者 潘志宇 余少卿 +2 位作者 张晓林 常永军 李敬文 《中国耳鼻咽喉头颈外科》 CSCD 2022年第11期738-739,共2页
1 临床资料 患者,男,75岁,因反复左鼻出血半月余,于2021-09-16入院。患者半月余前无明显诱因下突然出现左鼻出血,出血量中,不能自止,无全身性出血,无紫癜、瘀斑、呕血等症状。行鼻腔填塞后出血明显缓解,但仍有间断渗血;随后出现嗅觉减... 1 临床资料 患者,男,75岁,因反复左鼻出血半月余,于2021-09-16入院。患者半月余前无明显诱因下突然出现左鼻出血,出血量中,不能自止,无全身性出血,无紫癜、瘀斑、呕血等症状。行鼻腔填塞后出血明显缓解,但仍有间断渗血;随后出现嗅觉减退及左侧面部胀痛,持续1周。查体:鼻腔黏膜稍充血,左侧鼻腔嗅区及中鼻道充满灰褐色新生物,表面光滑,触之易出血。 展开更多
关键词 肉瘤(Sarcoma) 鼻腔(Nasal Cavity) 鼻窦肿瘤(paranasal sinus neoplasms) S100蛋白(S100 Proteins) 平滑肌肌球蛋白(Smooth Muscle Myosins)
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Improved Performance in Differentiating Benign from Malignant Sinonasal Tumors Using Diffusion-weighted Combined with Dynamic Contrast-enhanced Magnetic Resonance Imaging 被引量:10
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作者 Xin-Yan Wang Fei Yan +3 位作者 Hui Hao Jian-Xing Wu Qing-Hua Chen Jun-Fang Xian 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第5期586-592,共7页
Background:Differentiating benign from malignant sinonsal lesions is essential for treatment planning as well as determining the patient's prognosis,but the differentiation is often difficult in clinical practice.Th... Background:Differentiating benign from malignant sinonsal lesions is essential for treatment planning as well as determining the patient's prognosis,but the differentiation is often difficult in clinical practice.The study aimed to determine whether the combination of diffusion-weighted (DW) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can improve the performance in differentiating benign from malignant sinonasal tumors.Methods:This retrospective study included 197 consecutive patients with sinonasal tumors (116 malignant tumors and 81 benign tumors).All patients underwent both DW and DCE-MRI in a 3-T magnetic resonance scanner.Two different settings ofb values (0,700 and 0,1000 s/mm^2) and two different strategies of region of interest (ROI) including whole slice (WS) and partial slice (PS) were used to calculate apparent diffusion coefficients (ADCs).A DW parameter with WS ADCsb0.1000 and two DCE-MRI parameters (time intensity curve [TIC] and time to peak enhancement [Tpeak]) were finally combined to use in differentiating the benign from the malignant tumors in this study.Results:The mean ADCs of malignant sinonasal tumors (WS ADCsb0,1000=1.084 × 10^-3 mm^2/s) were significantly lower than those of benign tumors (WS ADCsb0,1000=1.617 × 10^-3 mm^2/s,P 〈 0.001).The accuracy using WS ADCsb0,1000 alone was 83.7% in differentiating the benign from the malignant tumors (85.3% sensitivity,81.2% specificity,86.4% positive predictive value [PPV],and 79.5% negative predictive value [NPV]).The accuracy using DCE with Tpeak and TIC alone was 72.1% (69.1% sensitivity,74.1% specificity,77.5% PPV,and 65.1% NPV).Using DW-MRI parameter was superior than using DCE parameters in differentiation between benign and malignant sinonasal tumors (P 〈 0.001).The accuracy was 87.3% (90.5% sensitivity,82.7% specificity,88.2% PPV,and 85.9% NPV) using DW-MRI combined with DCE-MRI,which was superior than that using DCE-MRI alone or using DW-MRI alone (both P 〈 0.001) in differentiating the benign from the malignant tumors.Conclusions:Diffusion-weighted combined with DCE-MRI can improve imaging performance in differentiating benign from malignant sinonasal tumors,which has the potential to improve diagnostic accuracy and to provide added value in the management for these tumors. 展开更多
关键词 DIFFUSION-WEIGHTED Dynamic Contrast-enhanced Magnetic Resonance Imaging Nasal Cavity Neoplasm paranasal sinus
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