Seventy-eight cases of retinoblastoma (Rb) diagnosed at the Eye ENT Hospital, Shanghai Medical University from 1953 to 1985 were studied. The results of multiple logistic regression analysis and conditional probabilit...Seventy-eight cases of retinoblastoma (Rb) diagnosed at the Eye ENT Hospital, Shanghai Medical University from 1953 to 1985 were studied. The results of multiple logistic regression analysis and conditional probability model showed that high fetal order had a moderate risk (OR=1.28, P<0.05) of developing unilateral Rb. Both unilateral and bilateral cases were independent of parental ages, and no interaction could be found between fetal order and paternal of maternal age; also, the effect of fetal order was not confounded by parental ages.展开更多
Understanding the relationship between fish parental age and offspring performance over their life cycle is crucial for aquaculturists.This study investigates the effect of parental age for both 1-and 2-year-old fish ...Understanding the relationship between fish parental age and offspring performance over their life cycle is crucial for aquaculturists.This study investigates the effect of parental age for both 1-and 2-year-old fish on the growth and survival rates of their larval to grow-out stages for two wild and domesticated strains of bighead catfish(Clarias macrocephalus).Fish were sampled from the Vietnamese Mekong Delta where wild adult fish were collected from a conservation area in Ca Mau Province and domesticated fish were taken from a hatchery in Can Tho.Four offspring treatments of 1-and 2-year-old broodstock strains were reared for 3 successive periods:40 days for fingerling rearing in static tanks with water exchange,60 days for juveniles,and 90 days for grow-out in recirculating systems.The final weight of fish at 190 days varied from 96.7 to 144.7 g.The growth of offspring was not affected by parental age(P>0.05),over the 3 rearing periods.However,the domesticated fish strain showed significantly better growth rates than the wild fish strain(P<0.05).Feed conversion ratios were comparable across fish treatments.Survival rates did not differ at the fingerling(21.8%-36.4%)and juvenile(69.0%-73.3%)stages.However,significant differences were found at the grow-out stage(69.3%-84.0%),with offspring from 2-year-old parents of both strains having greater survival rates.Overall,1-and 2-year-old fish appear to be suitable for bighead catfish breeders.展开更多
The early earthquake warning system in China is being improved to issue alerts five to 10 seconds after tremors occur, said Pan Huaiwen, head of the China Earthquake Networks Center （CENC）.
Background： Genetic factors are the main cause of early miscarriage. This study aimed to investigate aneuploidy in spontaneous abortion by fluorescence in situ hybridization （FISH） using probes for 13, 16, 18, 21, ...Background： Genetic factors are the main cause of early miscarriage. This study aimed to investigate aneuploidy in spontaneous abortion by fluorescence in situ hybridization （FISH） using probes for 13, 16, 18, 21, 22, X and Y chromosomes. Methods： A total of 840 chorionic samples from spontaneous abortion were collected and examined by FISH. We analyzed the incidence and type of abnormal cases and sex ratio in the samples. We also analyzed the relationship between the rate of aneuploidy and parental age, the rate of aneuploidy between recurrent abortion and sporadic abortion, the difference in incidence of aneuploidy between samples from previous artificial abortion and those from no previous induced abortion. Results： A total of 832 samples were finally analyzed. 368 （44.23%） were abnormal, in which 84.24% （310/368） were aneuploidies and 15.76% （58/368） were polyploidies. The first was trisomyl6 （121/310）, followed by trisomy 22, and X monosomy. There was no significant difference in the rate ofaneuploidy in the advanced maternal age group （≥35 years old） and young maternal age group （〈35 years old）. However, the rate oftrisomy 22 and the total rate of trisomies 21, 13, and 18 （the number oftrisomy 21 plus trisomy 13 and trisomy 18 together） showed significantly different in two groups. We found no skewed sex ratio. There was no significant difference in the rate of aneuploidy between recurrent miscarriage and sporadic abortion or between the samples fi＇om previous artificial abortion and those from no previous artificial abortion. Conclusions： Aneuploidy is a principal factor of miscarriage and total parental age is a risk factor. There is no skewed sex ratio in spontaneous abortion. There is also no difference in the rate of aneuploidy between recurrent abortion and sporadic abortion or between previous artificial abortion and no previous induced abortion.展开更多
文摘Seventy-eight cases of retinoblastoma (Rb) diagnosed at the Eye ENT Hospital, Shanghai Medical University from 1953 to 1985 were studied. The results of multiple logistic regression analysis and conditional probability model showed that high fetal order had a moderate risk (OR=1.28, P<0.05) of developing unilateral Rb. Both unilateral and bilateral cases were independent of parental ages, and no interaction could be found between fetal order and paternal of maternal age; also, the effect of fetal order was not confounded by parental ages.
基金This study was funded in part by the Can Tho University Improvement Project VN14-P6,supported by a Japanese ODA loan.
文摘Understanding the relationship between fish parental age and offspring performance over their life cycle is crucial for aquaculturists.This study investigates the effect of parental age for both 1-and 2-year-old fish on the growth and survival rates of their larval to grow-out stages for two wild and domesticated strains of bighead catfish(Clarias macrocephalus).Fish were sampled from the Vietnamese Mekong Delta where wild adult fish were collected from a conservation area in Ca Mau Province and domesticated fish were taken from a hatchery in Can Tho.Four offspring treatments of 1-and 2-year-old broodstock strains were reared for 3 successive periods:40 days for fingerling rearing in static tanks with water exchange,60 days for juveniles,and 90 days for grow-out in recirculating systems.The final weight of fish at 190 days varied from 96.7 to 144.7 g.The growth of offspring was not affected by parental age(P>0.05),over the 3 rearing periods.However,the domesticated fish strain showed significantly better growth rates than the wild fish strain(P<0.05).Feed conversion ratios were comparable across fish treatments.Survival rates did not differ at the fingerling(21.8%-36.4%)and juvenile(69.0%-73.3%)stages.However,significant differences were found at the grow-out stage(69.3%-84.0%),with offspring from 2-year-old parents of both strains having greater survival rates.Overall,1-and 2-year-old fish appear to be suitable for bighead catfish breeders.
文摘The early earthquake warning system in China is being improved to issue alerts five to 10 seconds after tremors occur, said Pan Huaiwen, head of the China Earthquake Networks Center （CENC）.
文摘Background： Genetic factors are the main cause of early miscarriage. This study aimed to investigate aneuploidy in spontaneous abortion by fluorescence in situ hybridization （FISH） using probes for 13, 16, 18, 21, 22, X and Y chromosomes. Methods： A total of 840 chorionic samples from spontaneous abortion were collected and examined by FISH. We analyzed the incidence and type of abnormal cases and sex ratio in the samples. We also analyzed the relationship between the rate of aneuploidy and parental age, the rate of aneuploidy between recurrent abortion and sporadic abortion, the difference in incidence of aneuploidy between samples from previous artificial abortion and those from no previous induced abortion. Results： A total of 832 samples were finally analyzed. 368 （44.23%） were abnormal, in which 84.24% （310/368） were aneuploidies and 15.76% （58/368） were polyploidies. The first was trisomyl6 （121/310）, followed by trisomy 22, and X monosomy. There was no significant difference in the rate ofaneuploidy in the advanced maternal age group （≥35 years old） and young maternal age group （〈35 years old）. However, the rate oftrisomy 22 and the total rate of trisomies 21, 13, and 18 （the number oftrisomy 21 plus trisomy 13 and trisomy 18 together） showed significantly different in two groups. We found no skewed sex ratio. There was no significant difference in the rate of aneuploidy between recurrent miscarriage and sporadic abortion or between the samples fi＇om previous artificial abortion and those from no previous artificial abortion. Conclusions： Aneuploidy is a principal factor of miscarriage and total parental age is a risk factor. There is no skewed sex ratio in spontaneous abortion. There is also no difference in the rate of aneuploidy between recurrent abortion and sporadic abortion or between previous artificial abortion and no previous induced abortion.
