Pleiotrophin fights Brd2 for neuronal differentiation

Bromodomain containing 2 （Brd2） protein belongs to the Bromodomains and Extra Terminal domain （BET） family of chromatin adaptors characterized by the presence of two N-terminal tandem bromodomains and an exclusive C-terminal extra terminal domain （ET） （Belkina and Denis, 2012; Shi and Vakoc, 2014）. Bromodomains are involved in recognizing acetylated histone tails and other acetylated proteins while the ET domain has been implicated in protein-protein interaction.

Part-Time Nurse Faculty Intent to Remain Employed in Academia: A Cross-Sectional Study

The purpose of this study was to test and refine a model of part-time nurse faculty intent to remain employed in the academic organization. Cross-sectional survey methods were used. A total of 282 part-time nurse faculty working in colleges or universities in Ontario, Canada were invited to participate. Survey instruments and items measured demographic, workplace, nurse responses to the workplace, and external variables. Correlation, multiple regression, and mediation analyses were conducted using data from 119 participants (47.6% response rate). Of the 19 variables hypothesized to affect intent to remain employed in the academic organization, seven influenced intent to remain. The resulting model indicated that the older the part-time nurse faculty member, the lower the level of intent to remain and the more years worked in the organization, the higher the level of intent to remain. The more opportunities perceived to exist outside of the employing organization, the higher the level of intent to remain. Additionally, the more satisfied part-time nurse faculty were with their job overall, the higher their level of intent to remain. In the workplace, the more support from the leader, the more formal or informal recognition received, and the more fair work procedures were perceived to be, the higher levels of part-time nurse faculty intent to remain employed in the academic organization, mediated by job satisfaction. Although age, organizational tenure, and external career opportunities are non-modifiable variables, deans and directors can encourage part-time nurse faculty to remain employed in their academic job by focusing on enhancing overall job satisfaction. Effective strategies may include formal or informal acknowledgement of good performance, consistent verbal and behavioural support, and implementation of procedural practices, such as performance evaluations and pay raises in a fair manner.

A Realistic Portrayal of Reservation Life： A Postcolonial Reading of The Absolutely True Diary of a Part-Time Indian＊

The Absolutely True Diary of a Part-Time Indian is a 2007 National Book Award novel for young adults by Sherman Alexie. Inspired by his own experiences of growing up, award-winning author Sherman Alexie chronicles the contemporary adolescence of one unlucky boy trying to rise above the life everyone expects him to live. As a bildungsroman, the novel honestly depicts the real life in reservation as well as protagonist Arnold＇s personal development in misfortune. The novel addresses various themes. Through close reading of the novel and with the help of some theories from postcolonial criticism, the present paper tries to analyze the bleak reality of reservation life and protagonist Arnold＇s struggle for social success, thus interpreting the themes of othering, alienation, unhomeliness, double consciousness, and hope presented in the novel

Part-Time Learners’Perceptions of Success During Emergency Remote Teaching and Implications for Future

The Faculty of Lifelong Learning at South East Technological University’s Carlow campus is one of the largest providers of part-time,adult learning in the Irish HE sector.Therefore,the perspectives of our part-time learners offer us valuable insights into adult learner experiences in the Irish HE sector.The outbreak of Covid 19 saw us pivot our provision to an emergency remote teaching(ERT)model in the first wave of the epidemic.The faculty undertook an extensive study of its learners in 2021 to examine the impacts of ERT on learners,and this article takes a qualitative approach to the findings of this study,looking specifically at learners’comments about success,and the barriers to success,which ERT posed.Our study provided an opportunity to learn about our learners’conceptions of student identity,and how they interpret success as part-time learners.

Difficulties and Breakthrough Strategies in the Team Construction of Part-time Teachers in Application-oriented Universities

Strengthening the team construction of part-time teachers is required by the transformation and development of the universities,the realization of their goals of being developed into an application-oriented universities and their talent cultivation and long-term development.The existing problem regarding the part-time teachers in current application-oriented universities are the low proportion of part-time teachers,a shortage of high level parttime teachers,the absence of relevant laws and regulations,a lack of systematic policies or financial support for part-time teachers as well as the unsound management mechanism with insufficient scientific and reasonable employment scheme for part-time teachers.To strengthen the team construction of the part-time teachers in application-oriented universities,firstly we should improve the existing laws,regulations and policies and broaden the financial support channels.Secondly,we should develop the recruitment channels for part-time teachers and pay attention to introducing high-tech and highly-skilled talents.Thirdly,we should improve the management over part-time teachers and promote their value.Fourthly,it should adopt a people-oriented management concept and establish an effective evaluation and incentive mechanism for part-time teachers.

Getting Into Fights

They were married,but since the argument they had a few days earlier,they hadnEt been talking to each other.

APEC Fights Ebola

UNDER blue Beijing skies November＇s Asia-Pacific Economic Cooperation （APEC） Summit 2014 made a firm statement in the fight against the Ebola epidemic. The deadly disease was one of the central topics President Xi Jinping and President Barack Obama discussed during their bilateral talks on the sidelines of the APEC Informal Leaders＇ Meeting.

啮齿类动物Playfighting的行为学研究进展

Playfighting是一种常见的社会性互动形式,具有互惠性和合作性等特点。其贯穿于动物的整个生命周期,并且会通过影响动物的社交、认知和运动等进一步影响大脑的执行功能。啮齿类动物的playfighting行为因具有易识别、易量化等特点,而被广泛研究。本文主要以大鼠和金仓鼠为例,整理概述了近年来啮齿类动物playfighting行为的研究现状,包括行为模式及其相关影响因素,希望为今后进一步研究playfighting行为提供参考。

中华优秀传统廉洁文化融入高校思政课论析

中华优秀传统廉洁文化贯古通今、蔚为大观,将其融入思政课程,有利于党的事业薪火相传、永续发展,有利于当代学生启智润心、立根塑魂,有利于思政课程提质增效、与时俱进。中华优秀传统廉洁文化内涵丰富,包括律己以廉、清廉自洁的传统廉洁文化精华,戒奢尚俭、克己奉公的廉洁自律道德操守,德法并举、廉为政本的传统廉洁文化氛围。在融入过程中,需要统筹布局顶层规划,坚持系统性原则、实践性原则、灵活性原则,以塑造育人机制;坚持融料融点融机,立足学科专业、着眼育人目标、紧扣热点堵点,以提升融入效能;加强课程体系建设,抓住时代之问、结合学术逻辑、融入现实生活,以深化课程逻辑。

无人机在消防救援中的应用研究

无人机技术在消防灭火救援中扮演着非常重要的角色,不仅优化了传统救援方式,还提高了灭火效率和救援人员的安全性。文章介绍了火灾救援面临的风险与挑战,论述了无人机技术在消防领域的应用优缺点,阐释了应用无人机参与灭火救援的重要性,并在相关政策基础上指出了无人机在消防领域的发展前景。

轮式格斗机器人的设计与实现

面向本科机器人方向实践教学,设计一款轮式格斗机器人。该机器人可以实现自主登台、自动巡航、自主视觉寻敌攻击、落台后重新登台等功能。首先,进行机器人的机械结构设计。通过合理的机械结构设计以及合理的传感器安装布置,可以有效改善机器人的结构强度、灵活性、稳定性和机动性。其次,进行机器人控制系统设计,其中,包括机器人控制系统元器件选型设计、机器人的控制策略及控制算法设计、路径规划算法设计、目标识别与视觉跟踪算法设计。最后,采用现场测试的方法对机器人的性能进行优化提升。在不同环境下,通过机器人现场表现进行测试和分析,评估机器人的性能和稳定性,并针对性地进行改进和优化。通过轮式格斗机器人的设计与实现训练,有助于提升机器人工程专业本科生在机器人领域的设计实践和问题分析能力。

客运架空索道应急救援处置初探

客运架空索道是一种高空远距离的交通工具,其安全性和可靠性是非常重要的,但在特殊情况下,如因自然灾害或技术故障等造成紧急情况,客运架空索道的应急救援处置就显得尤为重要。本文分析客运架空索道事故情况,对索道应急救援处置进行了探讨,并给出救援对策建议。

新质战斗力背景下大模型赋能国防科技创新路径预测研究

[目的/意义]国防科技创新助力新质战斗力发展已成为我国战略需求,有效预测国防科技创新路径对于切实提高国防科技创新能力、打造我国新质战斗力具有重要意义。[方法/过程]针对国防科技创新突变性、不确定性与高风险性特征,文章根据国防科技创新路径预测核心要素,构建大模型赋能国防科技创新路径预测逻辑框架,利用军事需求识别、军工企业关键技术预测与创新政策挖掘子模型,对国防科技创新路径预测进行理论分析。[结果/结论]研究发现,大模型能够有效预测国防科技的发展趋势和关键技术突破点,为国防科技创新决策提供科学依据,切实推动新质生产力与新质战斗力深度融合。

基于灭火救援指挥箱的化学泄漏事故辅助决策分析

在化学泄漏事故应急处置过程中,如何借助辅助手段和先进技术提高指挥决策的科学性,是目前指挥员急需解决的重要问题。在总结化学泄漏事故特点的基础上,结合灭火救援指挥箱的系统功能,分析了应急决策的方法和原则。以氨气泄漏事故为例,利用灭火救援指挥箱在信息查询、危害评估、态势标绘等方面的功能,分析了指挥员在查询事故信息、预测灾情变化、了解现场情况、部署救援力量以及制订救援方案的决策依据,从而为消防救援指挥员化学事故处置提供参考。

基于无人机倾斜摄影的地质综合测绘技术

以往的地质测绘方法主要运用单点测量的方式以点带面得到地质信息,存在坡面高程相对误差较大的问题,因此,本文提出以无人机倾斜摄影为核心的地质综合测绘技术。确定无人机合理的航行高度范围,结合侧视影像临界点规划无人机倾斜摄影航线。按照航线控制无人机采集全方面测绘数据,并进行测绘数据筛选和纠正。通过特征提取、影像匹配、运动恢复结构等环节,进行地质环境三维重建,再应用多视图立体视觉算法实现点云加密。依托于Delaunay三角网构建算法,生成地质测绘可视化场景,完成地质综合测绘。实验结果表明,应用本文设计的测绘技术得到的坡面高程测量值与实际值一致性较高,相对误差总是低于2%,符合地质测绘要求。

Whole-genome resequencing infers genomic basis of giant phenotype in Siamese fighting fish(Betta splendens)

Understanding the genetic basis of phenotypes is of importance in evolutionary biology and for genetic improvement of economically valuable animals.The giant phenotype of the fighting fish,Betta splendens,provides a unique opportunity to explore the genetic architecture of overgrowth in body size.As such,we re-sequenced and analyzed the genomes of 54 fighting fish.Genome-wide FST and selective sweep analyses using 3582429 DNA variants revealed three genomic regions at chr1,chr9,and chr11 that were associated with the giant phenotype.With a total length of~3.5 Mb,these regions showed high divergence between the giant and non-giant bettas.In contrast,no signature of selection was detected in the wild-type fish.Transcriptome analysis of brain and muscle samples from giant and normal bettas identified 14 candidate genes that were likely responsible for the giant phenotype.Overall,our data provide novel insights into the genetic basis of body size variation.The genome sequences,transcriptome sequences,DNA sequence variants,and candidate genes for body size provide valuable resources for further biological and evolutionary studies,as well as for rapid improvement in growth-related traits.

Three-Dimensional Kinematics Simulation of Robot Fighting Platform in Virtual Environment

A method of 3 D kinematics simulation of robot fighting platform （RFP） in virtual environment is proposed with the aim of enhancing vision telepresence. Based on the theory of space coordinate transformation, kinematics equat!ons of RFP are formulated; followed by applying a method of modeling using 3DMAX software to build an RFP＇s 3D geometric model before a 3D kinematics simulation system of RFP is completed based on virtual reality technology and Open Inventor VC ＋ ＋. Test results have indicated that this system can perform RFP＇s kinematics simulation in virtual environment. It can also imitate RFP＇s motion states and environmental features well. Moreover, not only can better real-time performances and interactions be achieved but also operator＇s vision telepresence be enhanced, therefore this approach may help lay the foundation for the realization of RFP＇s teleoperation with vision telepresence.

Fight fire with fire?Promoting physical activity and health through active video games

Physical inactivity has been identified as one of the leading causes of many chronic diseases such as cardiovascular disease,type 2 diabetes,and obesity.Technology such as video games plays a complicated role in physical inactivity—much like a double-edged sword.Traditionally,video games have contributed to the epidemic of physical inactivity and have

New neuroprotective perspectives in fighting oxidative stress and improving cellular energy metabolism by oleocanthal

Neurodegenerative diseases are a heterogeneous group of disorders characterized by a progressive dysfunction and death of neural cells which lead to compromised motor or cognitive function.Morphologically,the loss of neuron is associated with both gliosis and,frequently,with abnormal accumulation of extracellular and intracellular filamentous deposit in specific cell types.With a rapidly increasing aging population,these diseases are becoming a primary health problem(Albers and Beal,2000).

Using Link Analysis Technique with a Modified Shortest-Path Algorithm to Fight Money Laundering

Effective link analysis techniques are needed to help law enforcement and intelligence agencies fight money laundering. This paper presents a link analysis technique that uses a modified shortest-path algorithms to identify the strongest association paths between entities in a money laundering network. Based on two-tree Dijkstra and Priority＇First-Search （PFS） algorithm, a modified algorithm is presented. To apply the algorithm, a network representation transformation is made first.