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Carbon dioxide partial pressure and carbon fluxes of air-water interface in Taihu Lake, China 被引量:2
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作者 范成新 胡维平 +3 位作者 Phillip W. Ford 陈宇炜 瞿文川 张路 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2005年第1期29-38,共10页
To obtain carbon dioxide (CO2) flux between water-air interface of Taihu lake, monthly water samplers at 14 sites and the local meteorological data of the lake were collected and analyzed in 1998. Carbon dioxide par... To obtain carbon dioxide (CO2) flux between water-air interface of Taihu lake, monthly water samplers at 14 sites and the local meteorological data of the lake were collected and analyzed in 1998. Carbon dioxide partial pressures (pCO2) at air-water interface in the lake were calculated using alkalinity, pH, ionic strength, active coefficient, and water temperature. The carbon fluxes at different sublakes and areas were estimated by concentration gradient between water and air in consideration of Schmidt numbers of 600 and daily mean windspeed at 10 m above water surface. The results indicated that the mean values of pCO2 in Wuli Lake,Meiliang Bay, hydrophyte area, west littoral zone, riverine mouths, and the open lake areas were 1 807.8±1 071.4(mean±standard deviation)μatm (latm=1.013 25×10^5pa), 416.3±217.0μatm, 576.5±758.8μatm, 304.2±9.43.5μatm, 1 933.6±1 144.7 μatm, and 448.5±202.6μatm, respectively. Maximum and minimum pCO2 values were found in the hypertrophic (4 053.7μatm) and the eutrophic (3.2 μatm) areas. The riverine mouth areas have the maximum fluxes (82.0±62.8 mmol/m^2a). But there was no significant difference between eutrophic and mesotrophic areas in pCO2 and the flux of CO2. The hydrophyte area, however, has the minimum (--0.58±12.9mmol/m^2a). In respect to CO2 equilibrium, input of the rivers will obviously influence inorganic carbon distribution in the riverine estuary. For example, the annual mean CO2 flux in Zhihugang River estuary was 19 times of that in Meiliang Bay, although the former is only a part of the latter. The sites in the body of the lake show a clear seasonal cycle with pCO2 higher than atmospheric equilibrium in winter, and much lower than atmospheric in summer due to CO2 consumption by photosynthesis. The CO2 amount of the net annual evasion that enters the atmosphere is 28.42×10^4 t/a, of which those from the west littoral zone and the open lake account for 53.8% and 36.7%, respectively. 展开更多
关键词 carbon dioxide partial pressure air-water interface carbon flux trophic area river input Taihu Lake
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Changes of end-tidal carbon dioxide during cardiopulmonary resuscitation from ventricular f ibrillation versus asphyxial cardiac arrest 被引量:7
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作者 Qing-ming Lin Xiang-shao Fang +3 位作者 Li-li Zhou Yue Fu Jun Zhu Zi-tong Huang 《World Journal of Emergency Medicine》 CAS 2014年第2期116-121,共6页
BACKGROUND: Partial pressure of end-tidal carbon dioxide(PETCO2) has been used to monitor the effectiveness of precordial compression(PC) and regarded as a prognostic value of outcomes in cardiopulmonary resuscitation... BACKGROUND: Partial pressure of end-tidal carbon dioxide(PETCO2) has been used to monitor the effectiveness of precordial compression(PC) and regarded as a prognostic value of outcomes in cardiopulmonary resuscitation(CPR). This study was to investigate changes of PETCO2 during CPR in rats with ventricular fi brillation(VF) versus asphyxial cardiac arrest.METHODS: Sixty-two male Sprague-Dawley(SD) rats were randomly divided into an asphyxial group(n=32) and a VF group(n=30). PETCO2 was measured during CPR from a 6-minute period of VF or asphyxial cardiac arrest.RESULTS: The initial values of PETCO2 immediately after PC in the VF group were signifi cantly lower than those in the asphyxial group(12.8±4.87 mmHg vs. 49.2±8.13 mmHg, P=0.000). In the VF group, the values of PETCO2 after 6 minutes of PC were significantly higher in rats with return of spontaneous circulation(ROSC), compared with those in rats without ROSC(16.5±3.07 mmHg vs. 13.2±2.62 mmHg, P=0.004). In the asphyxial group, the values of PETCO2 after 2 minutes of PC in rats with ROSC were signifi cantly higher than those in rats without ROSC(20.8±3.24 mmHg vs. 13.9±1.50 mmHg, P=0.000). Receiver operator characteristic(ROC) curves of PETCO2 showed signifi cant sensitivity and specifi city for predicting ROSC in VF versus asphyxial cardiac arrest.CONCLUSIONS: The initial values of PETCO2 immediately after CPR may be helpful in differentiating the causes of cardiac arrest. Changes of PETCO2 during CPR can predict outcomes of CPR. 展开更多
关键词 partial pressure of end-tidal carbon dioxide Cardiac arrest Cardiopulmonary resuscitation Return of spontaneous circulation RATS
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Arterial and End-Tidal Carbon Dioxide in Supine Obese Patients during General Anesthesia
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作者 Kenichi Satoh Mami Chikuda +4 位作者 Ayako Ohashi Miho Kumagai Masahito Sato Akiyoshi Kuji Shigeharu Joh 《Open Journal of Anesthesiology》 2015年第5期79-84,共6页
Background: We investigated the differences between partial pressure of arterial carbon dioxide and end-tidal carbon dioxide (P(a-ET)CO2) with respect to the Broca-Katsura index (BKI), which is an obesity index, in ob... Background: We investigated the differences between partial pressure of arterial carbon dioxide and end-tidal carbon dioxide (P(a-ET)CO2) with respect to the Broca-Katsura index (BKI), which is an obesity index, in obese patients during general anesthesia. Materials and Methods: From January 2003 to December 2013, we studied 601 patients aged 16 years old or over undergoing general anesthesia. Patients had American Society of Anesthesiology physical status I and II and we reviewed their anesthetic charts. The P(a-ET)CO2 with respect to the BKI divided patients into two groups: 16 to 2 values between the two groups. Results: In patients aged 16 to 2 was 2.2 ± 3.1 mmHg at BKI 2 was 3.2 ± 4.1 mmHg at BKI 2 tends to increase in obese patients during general anesthesia with increasing BKI in patients aged 16 to < 65 years old. 展开更多
关键词 arterial-Alveolar carbon dioxide Tension Difference Broca-Katsura index End-Tidal carbon dioxide partial pressure of arterial carbon dioxide SUPinE Position
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Temporal and spatial variability of the carbon cycle in the east of China's seas:a three-dimensional physical-biogeochemical modeling study 被引量:1
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作者 JI Xuanliang LIU Guimei +2 位作者 GAO Shan WANG Hui ZHANG Miaoyin 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2017年第3期60-71,共12页
In the east of China's seas, there is a wide range of the continental shelf. The nutrient cycle and the carbon cycle in the east of China's seas exhibit a strong variability on seasonal to decadal time scales. On th... In the east of China's seas, there is a wide range of the continental shelf. The nutrient cycle and the carbon cycle in the east of China's seas exhibit a strong variability on seasonal to decadal time scales. On the basis of a regional ocean modeling system(ROMS), a three dimensional physical-biogeochemical model including the carbon cycle with the resolution(1/12)°×(1/12)° is established to investigate the physical variations, ecosystem responses and carbon cycle consequences in the east of China's seas. The ROMS-Nutrient Phytoplankton Zooplankton Detritus(NPZD) model is driven by daily air-sea fluxes(wind stress, long wave radiation, short wave radiation, sensible heat and latent heat, freshwater fluxes) that derived from the National Centers for Environmental Prediction(NCEP) reanalysis2 from 1982 to 2005. The coupled model is capable of reproducing the observed seasonal variation characteristics over the same period in the East China Sea. The integrated air-sea CO_2 flux over the entire east of China's seas reveals a strong seasonal cycle, functioning as a source of CO_2 to the atmosphere from June to October, while serving as a sink of CO_2 to the atmosphere in the other months. The 24 a mean value of airsea CO_2 flux over the entire east of China's seas is about 1.06 mol/(m^2·a), which is equivalent to a regional total of3.22 Mt/a, indicating that in the east of China's seas there is a sink of CO_2 to the atmosphere. The partial pressure of carbon dioxide in sea water in the east of China's seas has an increasing rate of 1.15 μatm/a(1μtm/a=0.101 325Pa), but p H in sea water has an opposite tendency, which decreases with a rate of 0.001 3 a^(–1) from 1982 to 2005.Biological activity is a dominant factor that controls the pCO_2 air in the east of China's seas, and followed by a temperature. The inverse relationship between the interannual variability of air-sea CO_2 flux averaged from the domain area and Ni?o3 SST Index indicates that the carbon cycle in the east of China's seas has a high correlation with El Ni?o-Southern Oscillation(ENSO). 展开更多
关键词 the east of China's seas physical-biogeochemical model partial pressure of carbon dioxide in sea water air-sea CO2 flux
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How and why chemicals from tobacco smoke can induce a rise in blood pressure
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作者 Aurelio Leone 《World Journal of Pharmacology》 2012年第1期10-20,共11页
The primary objective of this article is to analyze the role of tobacco smoke compounds able to damage the cardiovascular system and, in particular, to interfere with blood pressure. They are products of tobacco plant... The primary objective of this article is to analyze the role of tobacco smoke compounds able to damage the cardiovascular system and, in particular, to interfere with blood pressure. They are products of tobacco plant leaves, like nicotine, thiocyanate and aromatic amines, and a chemical derived from cigarette com-bustion, carbon monoxide. Of the other thousands of chemicals, there is no clear evidence of cardiovascular damage. Nicotine and its major metabolite, cotinine, usually increase blood pressure by a direct action and an action stimulating neuro-humoral metabolites of the body as well as sympathetic stimulation. An indirect mechanism of damage exerted by elevated carboxyhe-moglobin concentrations is mediated by carbon mon-oxide, which, mainly induces arterial wall damage and, consequently, late rising in blood pressure by a toxic direct action on endothelial and blood cells. Thiocya-nate, in turn, reinforces the hypoxic effects determined by carbon monoxide. Aromatic amines, depending on their chemical structure, may exert toxic effects on the cardiovascular system although they have little effect on blood pressure. A rise in blood pressure determined by smoking compounds is a consequence of both their direct toxicity and the characteristics of their chemical chains that are strongly reactive with a large number of molecules for their spatial shape. In addition, a rise in blood pressure has been documented in individuals smoking a cigarette, acutely and chronically, with irre-versible artery wall alterations several years after begin-ning smoking. Since cigarette smoking has a worldwide diffusion, the evidence of this topic meets the interest of both the scientifc community and those individuals aiming to control smoking. 展开更多
关键词 Smoking chemicals blood pressure NICOTinE carbon monoxide arterial damage
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pCO_2 and carbon fluxes across sea-air interface in the Changjiang Estuary and Hangzhou Bay 被引量:6
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作者 高学鲁 宋金明 +2 位作者 李学刚 李宁 袁华茂 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2008年第3期289-295,共7页
Partial pressure of CO2(pCO2) was investigated in the Changjiang(Yangtze River) Estuary,Hangzhou Bay and their adjacent areas during a cruise in August 2004,China.The data show that pCO2 in surface waters of the studi... Partial pressure of CO2(pCO2) was investigated in the Changjiang(Yangtze River) Estuary,Hangzhou Bay and their adjacent areas during a cruise in August 2004,China.The data show that pCO2 in surface waters of the studied area was higher than that in the atmosphere with only exception of a patch east of Zhoushan Archipelago.The pCO2 varied from 168 to 2 264 μatm,which fell in the low range compared with those of other estuaries in the world.The calculated sea-air CO2 fluxes decreased offshore and varied from -10.0 to 88.1 mmol m-2 d-1 in average of 24.4 ± 16.5 mmol m-2 d-1.Although the area studied was estimated only 2 × 104 km2,it emitted(5.9 ± 4.0) × 103 tons of carbon to the atmosphere every day.The estuaries and their plumes must be further studied for better understanding the role of coastal seas playing in the global oceanic carbon cycle. 展开更多
关键词 partial pressure of carbon dioxide spatial distribution sea-air exchange Changjiang Estuary Hangzhou Bay
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Analysis of metabolic alterations in Arabidopsis following changes in the carbon dioxide and oxygen partial pressures 被引量:2
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作者 Alexandra Florian Stefan Timm +4 位作者 Zoran Nikoloski Takayuki Tohge Hermann Bauwe Wagner L.Araujo Alisdair R.Fernie 《Journal of Integrative Plant Biology》 SCIE CAS CSCD 2014年第9期941-959,共19页
As sessile organisms,plants are subject to a multitude of environmental variations including several which directly affect their interaction with the atmosphere.Given the indiscriminant nature of Rubisco,the relative ... As sessile organisms,plants are subject to a multitude of environmental variations including several which directly affect their interaction with the atmosphere.Given the indiscriminant nature of Rubisco,the relative rates of photosynthesis and photorespiration are known to be responsive to changes in gas composition.However,comprehensive profiling methods have not yet been applied in order to characterize the wider consequences of these changes on primary metabolism in general.Moreover,although transcriptional profiling has revealed that a subset of photorespiratory enzymes are co-expressed,whether transcriptional responses play a role in short-term responses to atmospheric compositional changes remains unknown.To address these questions,plants Arabidopsis thaliana(Arabidopsis) ecotype Columbia(Col-O) grown under normal air conditions were transferred to different CO_2 and O_2 concentrations and characterized at the physiological,molecular,and metabolic levels following this transition.The results reveal alterations in the components,which are directly involved in,or supporting,photorespiration,including transcripts and metabolite levels.The results further highlight that the majority of the regulation of these pathways is not mediated at the level of transcription and that the photorespiratory pathway is essential also in conditions in which flux through the pathway is minimized,yet suggest that flux through this pathway is not mediated at the level of transcription. 展开更多
关键词 carbon dioxide partial pressures gene expression metabolic profiling oxygen partial pressures
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Reconstructing sea surface temperature, sea surface salinity and partial pressure of carbon dioxide in atmosphere in the Okinawa Trough during the Holocene and their paleoclimatic implications 被引量:3
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作者 MENGXianwei LIUYanguang +3 位作者 LlUZhenxia DUDewen HUANGQiyu Y.Saito 《Chinese Science Bulletin》 SCIE EI CAS 2003年第B06期88-92,共5页
The sediment core DGKS9603 collected from the Okinawa Trough was used as research target. By use of unsaturated index U37^k of long-chain alkenone, δ^13C of POC and of planktonic foraminifera (G sacculifer), the evol... The sediment core DGKS9603 collected from the Okinawa Trough was used as research target. By use of unsaturated index U37^k of long-chain alkenone, δ^13C of POC and of planktonic foraminifera (G sacculifer), the evolutions of sea surface temperature and partial pressure of carbon dioxide in the atmosphere during the Holocene were reconstructed in the Okinawa Trough. And in combination of δ^18O of planktonic foraminifera, the relative difference of sea surface salinity during the Holocene was also reconstructed.Consequently, three cooling events (E1-E3) were identified,each of which occurred at 1.7-1.6, 5.1-4.8 and 8.1-7.4kaBP (cal), respectively. Of the three events, E2 and E3 are globally comparable, their occurrence mechanism would be that the main stream of the Kuroshio Current shifted eastward due to the enhanced circulation of the northeastern Pacific Ocean, which was driven in turn by amplified intensity of sunshine and subsequent enhancement of subtropical high pressure; E1 corresponds to the Small Ice-Age Event occurring between 1550 and 1850AD in China. In the Okinawa Trough, E1 might be also related to the eastward shift of main stream of the Kuroshio current driven by powerful Asia winter monsoon. 展开更多
关键词 冲绳岛海槽 全新世 二氧化碳 温度 盐度 日本海流 亚热带高气压 太平洋 气候变化
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通气效率和静息潮气末二氧化碳分压对肺癌切除术后心肺并发症的预测价值
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作者 魏丽丽 孙嗣善 韩锦胜 《临床肿瘤学杂志》 CAS 2024年第6期591-595,共5页
目的分析每分钟通气量与二氧化碳输出量(V_(E)/VCO_(2))斜率和静息潮气末二氧化碳分压(PetCO_(2))对肺癌切除术后心肺并发症的预测价值。方法收集2020年3月至2023年11月期间201例接受肺切除手术的早期非小细胞肺癌患者。所有患者术前均... 目的分析每分钟通气量与二氧化碳输出量(V_(E)/VCO_(2))斜率和静息潮气末二氧化碳分压(PetCO_(2))对肺癌切除术后心肺并发症的预测价值。方法收集2020年3月至2023年11月期间201例接受肺切除手术的早期非小细胞肺癌患者。所有患者术前均进行肺功能检查、心肺运动试验。随访记录患者术后30 d内的术后心肺并发症、重症监护病房(ICU)住院时间(LOS)、医院LOS、ICU再次入住率和死亡率。结果共有32例患者发生术后心肺并发症,纳入并发症组,其余患者纳入无并发症组(n=169)。并发症组患者的医院LOS、ICU LOS、ICU再次入住率均高于无并发症组(P<0.05)。与无并发症组相比,并发症组静息PetCO_(2)、V_(E)/VCO_(2)斜率显著升高(P<0.05)。经单因素及多因素Logistics分析,静息PetCO_(2)、V_(E)/VCO_(2)斜率为肺癌切除术后发生心肺并发症的独立影响因素(P<0.05)。静息PetCO_(2)预测肺癌切除术后发生心肺并发症的受试者工作特征曲线下面积为0.810(95%CI:0.741~0.880),与VE/VCO_(2)斜率[0.795(95%CI:0.720~0.871)]无显著差异。经Spearman秩相关分析及多元线性回归校正,静息PetCO_(2)与ICU LOS(r=-0.295,P<0.001)、医院LOS((V-0.271,P<0.001)呈负相关;VE/VCO_(2)斜率与ICU LOS(r=0.314,P<0.001)、医院LOS(r=0.301,P<0.001)呈正相关。结论静息PetCO_(2)和V_(E)/VCO_(2)斜率预测肺癌切除术后心肺并发症效能相似,这表明静息PetCO_(2)可以作为不能或不愿意接受CPET的患者的V_(E)/VCO_(2)斜率替代品。 展开更多
关键词 每分钟通气量与二氧化碳输出量 静息潮气末二氧化碳分压 肺癌 肺切除术 心肺并发症
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动态监测经皮血气分析指标和炎性指标对新生儿呼吸窘迫综合征并发支气管肺发育不良的预测价值
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作者 杨华蕾 王小雷 +2 位作者 田金凤 魏培培 聂军红 《实用临床医药杂志》 CAS 2024年第14期60-66,共7页
目的探讨动态监测经皮氧分压[p_(tc)(O_(2))]、经皮二氧化碳分压[p_(tc)(CO_(2))]与血清淀粉样蛋白A(SAA)、白细胞介素-6(IL-6)水平对新生儿呼吸窘迫综合征(NRDS)患儿并发支气管肺发育不良(BPD)的预测价值。方法选取240例NRDS患儿作为... 目的探讨动态监测经皮氧分压[p_(tc)(O_(2))]、经皮二氧化碳分压[p_(tc)(CO_(2))]与血清淀粉样蛋白A(SAA)、白细胞介素-6(IL-6)水平对新生儿呼吸窘迫综合征(NRDS)患儿并发支气管肺发育不良(BPD)的预测价值。方法选取240例NRDS患儿作为研究对象,根据是否并发BPD分为BPD组108例和非BPD组132例。比较2组患儿出生后第1、7、14天时p_(tc)(O_(2))、p_(tc)(CO_(2))、SAA、IL-6水平,采用Spearman相关分析法探讨各指标间的相关性及其与病情程度的相关性,采用相对危险度(RR)和95%置信区间(CI)评价各指标对NRDS患儿并发BPD的影响,采用受试者工作特征(ROC)曲线、决策曲线分析各指标预测BPD的效能及临床净获益。结果出生后第1天,2组患儿p_(tc)(O_(2))、p_(tc)(CO_(2))和血清SAA、IL-6水平比较,差异均无统计学意义(P>0.05);出生后第7、14天,BPD组p_(tc)(O_(2))低于非BPD组,p_(tc)(CO_(2))和血清SAA、IL-6水平高于非BPD组,差异有统计学意义(P<0.05)。相关性分析结果显示,患儿BPD程度与出生后第7天时p_(tc)(O_(2))呈负相关(r=-0.724,P<0.05),与出生后第7天时p_(tc)(CO_(2))、SAA、IL-6呈正相关(r=0.635、0.830、0.715,P<0.05);患儿肺功能障碍程度与出生后第7天时p_(tc)(O_(2))呈负相关(r=-0.719,P<0.05),与出生后第7天时p_(tc)(CO_(2))、SAA、IL-6呈正相关(r=0.673、0.756、0.696,P<0.05);出生后第7天时,BPD患儿p_(tc)(O_(2))分别与SAA、IL-6呈负相关(r=-0.605、-0.623,P<0.05),p_(tc)(CO_(2))分别与SAA、IL-6呈正相关(r=0.618、0.650,P<0.05)。ROC曲线显示,出生后第7天p_(tc)(O_(2))、p_(tc)(CO_(2))、SAA、IL-6联合预测NRDS并发BPD的效能优于四者单独预测,曲线下面积为0.938(95%CI:0.899~0.965)。p_(tc)(CO_(2))、SAA、IL-6高表达者并发BPD的风险是低表达者的2.256、1.668、1.667倍,p_(tc)(O_(2))高表达者并发BPD的风险是低表达者的0.568倍。决策曲线分析结果显示,当阈值在0.2~0.9时,出生后第7天时p_(tc)(O_(2))、p_(tc)(CO_(2))、SAA、IL-6联合模型预测NRDS患儿合并BPD的净获益率优于四者单独预测。结论p_(tc)(O_(2))、p_(tc)(CO_(2))、SAA、IL-6均与NRDS并发BPD患儿病情严重程度密切相关,四者联合检测有助于提高对NRDS并发BPD的预测效能及净获益率。 展开更多
关键词 新生儿呼吸窘迫综合征 支气管肺发育不良 经皮氧分压 经皮二氧化碳分压 淀粉样蛋白A 白细胞介素-6
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经皮二氧化碳分压监测在硬质支气管镜下Feng′s EBUS-TBNB中的应用
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作者 骆玉兔 孙亚楠 +1 位作者 潘家华 万南生 《南通大学学报(医学版)》 2024年第1期45-48,共4页
目的:探讨经皮二氧化碳分压(transcutaneous partial pressure of carbon dioxide,PtcCO_(2))监测在硬质支气管镜下冯氏气管内超声引导纵隔切开活检(Feng′s endobronchial ultrasound-guided transbronchial node biopsy,Feng′s EBUS-... 目的:探讨经皮二氧化碳分压(transcutaneous partial pressure of carbon dioxide,PtcCO_(2))监测在硬质支气管镜下冯氏气管内超声引导纵隔切开活检(Feng′s endobronchial ultrasound-guided transbronchial node biopsy,Feng′s EBUS-TBNB)中的应用。方法:收集2019年8月—2022年8月期间天津医科大学总医院收治的纵隔疾病患者128例,随机分成Feng′s EBUS-TBNB组和支气管内超声引导针吸活检术(endobronchial ultrasound-guided transbronchial needle aspiration,EBUS-TBNA)组,患者均予高频喷射通气行硬质支气管镜下操作及PtcCO_(2)监测,EBUS-TBNA组患者行EBUS-TBNA,Feng′s EBUS-TBNB组患者行Feng′s EBUS-TBNB术,比较两组患者术前(T0)、通气开始时(T_(1))、通气10 min后(T_(2))、通气20 min后(T3)、通气30 min后(T_(4))、通气40 min后(T_(5))、通气50 min后(T_(6))、通气60 min后(T_(7))心率(heart rate,HR)、平均动脉压(mean arterial pressure,MAP)和PtcCO_(2)的变化。结果:T_(1)~T_(7)时,两组患者HR、MAP和PtcCO_(2)水平均明显高于T0时(P<0.05)。T0~T_(2)时,两组患者HR、MAP和PtcCO_(2)水平比较差异无统计学意义(P>0.05);T3~T_(5)时,Feng′s EBUS-TBNB组HR、MAP和PtcCO_(2)水平均明显高于EBUS-TBNA组(P<0.05);而T_(6)~T_(7)时,两组患者HR、MAP和PtcCO_(2)水平比较差异无统计学意义(P>0.05)。结论:将PtcCO_(2)应用于Feng′s EBUS-TBNB中,可间接反映患者HR、MAP水平变化,值得临床推广应用。 展开更多
关键词 纵隔疾病 经皮二氧化碳分压 硬质支气管镜 冯氏气管内超声引导纵隔切开活检 心率 平均动脉压
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腹腔镜手术中呼气末二氧化碳分压监测在临床麻醉中的应用
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作者 潘科 《襄阳职业技术学院学报》 2024年第1期102-104,共3页
目的探讨呼气末二氧化碳分压(PETCO_(2))监测能否准确反映全麻下腹腔镜手术在二氧化碳气腹下动脉血二氧化碳水平。方法回顾性分析2021年1月至2023年2月襄阳职业技术学院附属医院收治的80例全麻下腹腔镜手术患者的临床资料,监测二氧化碳... 目的探讨呼气末二氧化碳分压(PETCO_(2))监测能否准确反映全麻下腹腔镜手术在二氧化碳气腹下动脉血二氧化碳水平。方法回顾性分析2021年1月至2023年2月襄阳职业技术学院附属医院收治的80例全麻下腹腔镜手术患者的临床资料,监测二氧化碳气腹前后患者PETCO_(2)与动脉血二氧化碳分压(PaCO_(2))的变化,分析二者的相关性,同时记录手术期间发现不良事件的能力。结果患者二氧化碳气腹前后PETCO_(2)与PaCO_(2)的变化均有显著性差异(P<0.05);而发现术中不良事件的能力方面,PETCO_(2)灵敏性明显优于PaCO_(2),二者比较有极显著性差异(P<0.01)。结论临床麻醉中应用PETCO_(2)监测全麻下腹腔镜手术可以有效反映二氧化碳水平变化,具有连续性,亦能更及时发现手术中不良事件,有较高的临床价值。 展开更多
关键词 呼气末二氧化碳分压 腹腔镜手术 临床麻醉
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益气养阴汤联合西药治疗特发性肺纤维化缓解期临床研究 被引量:2
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作者 徐小小 叶新新 +1 位作者 李献超 潘锟镭 《新中医》 CAS 2024年第1期56-60,共5页
目的:观察益气养阴汤联合西药治疗特发性肺纤维化(IPF)缓解期的临床疗效。方法:采用随机数字表法将66例IPF缓解期患者分为试验组、对照组各33例。对照组给予常规西药治疗,试验组给予益气养阴汤联合西药治疗,2组连续治疗2个月。比较2组... 目的:观察益气养阴汤联合西药治疗特发性肺纤维化(IPF)缓解期的临床疗效。方法:采用随机数字表法将66例IPF缓解期患者分为试验组、对照组各33例。对照组给予常规西药治疗,试验组给予益气养阴汤联合西药治疗,2组连续治疗2个月。比较2组治疗前后中医证候积分、高分辨率CT(HRCT)半定量评分、肺功能指标[用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))、最大呼气峰流速(PEF)、肺总量(TLC)]、动脉血二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2)),评估2组临床疗效及不良反应发生情况。结果:试验过程中,试验组剔除2例,完成研究31例;对照组剔除3例,完成研究30例。治疗后,试验组总有效率为90.32%,高于对照组70.00%(P<0.05)。2组治疗后中医证候积分、HRCT半定量评分、PaCO_(2)水平均治疗前降低(P<0.05),PaO_(2)水平均升高(P<0.05);试验组治疗后中医证候积分、HRCT半定量评分、PaCO_(2)水平低于对照组(P<0.05),PaO_(2)水平高于对照组(P<0.05)。2组治疗后FVC、FEV_(1)、PEF、TLC水平均高于治疗前(P<0.05),且试验组治疗后肺功能指标均高于对照组(P<0.05)。试验组、对照组不良反应发生率分别为9.68%、13.33%,2组比较,差异无统计学意义(P>0.05)。结论:益气养阴汤联合西药治疗IPF缓解期疗效确切,能改善患者肺功能,缓解肺纤维化,安全性较高。 展开更多
关键词 特发性肺纤维化 缓解期 益气养阴汤 肺功能 动脉血二氧化碳分压 动脉血氧分压
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全麻术后苏醒期患者呼气末二氧化碳分压监测的研究进展
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作者 陈安龙 刘尚昆 +1 位作者 余遥 陈红 《护理学杂志》 CSCD 北大核心 2024年第17期126-128,F0003,共4页
综述呼气末二氧化碳分压监测在麻醉后苏醒室的应用,主要包括呼气末二氧化碳分压监测的优势、方法、波形分析及应用等,旨在为全麻术后苏醒期患者实施呼气末二氧化碳分压监测提供参考。
关键词 全身麻醉 麻醉苏醒室 苏醒期 呼气末二氧化碳分压 低氧血症 护理监测 综述文献
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感染性休克液体复苏完成时限对病情转归的影响
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作者 张丽 郑祥德 田琳 《临床误诊误治》 CAS 2024年第3期83-88,共6页
目的 探究感染性休克液体复苏完成时限对患者病情转归的影响。方法 选取2020年7月—2023年7月收治的感染性休克156例,根据液体复苏完成时限分为<1 h组68例、1~2 h组57例、≥2 h组31例。比较3组液体复苏前后急性生理和慢性健康状况评... 目的 探究感染性休克液体复苏完成时限对患者病情转归的影响。方法 选取2020年7月—2023年7月收治的感染性休克156例,根据液体复苏完成时限分为<1 h组68例、1~2 h组57例、≥2 h组31例。比较3组液体复苏前后急性生理和慢性健康状况评分(APACHEⅡ)、序贯器官衰竭评分(SOFA)、血流动力学指标[中心静脉压(CVP)、心指数、外周血管阻力指数(SVRI)、每搏量指数(SVI)]、血乳酸、pH值、动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))、血管外肺水指数(ELWI)、肺血管通透性指数(PVPI)、血肌酐、液体复苏量,以及去甲肾上腺素应用剂量、重症监护病房(ICU)住院时间、机械通气时间、28 d生存率。结果 <1 h组、1~2 h组复苏后APACHEⅡ、SOFA评分低于≥2 h组(P<0.05);≤1 h组、1~2 h组复苏后APACHEⅡ、SOFA评分无明显差异(P>0.05);<1 h组、1~2 h组复苏后CVP、心指数、SVI高于≥2 h组,SVRI低于≥2 h组(P<0.05);<1 h组、1~2 h组复苏后CVP、心指数、SVRI、SVI比较无明显差异(P>0.05)。<1 h组、1~2 h组复苏后血乳酸低于≥2 h组(P<0.05);<1 h组、1~2 h组复苏后血乳酸比较无明显差异(P>0.05);3组复苏后血pH值、PaO_(2)、PaCO_(2)比较无明显差异(P>0.05)。<1 h组复苏后ELWI、PVPI、血肌酐高于复苏前,并高于1~2 h组、≥2 h组(P<0.05);3组1 h液体复苏量比较无明显差异(P>0.05),<1 h组、1~2 h组、≥2 h组3 h液体复苏量呈依次降低趋势(P<0.05)。≥2 h组去甲肾上腺素剂量高于<1 h组、1~2 h组(P<0.05);<1 h组ICU住院时间、机械通气时间长于1~2 h组、≥2 h组(P<0.05)。1~2 h组、≥2 h组28 d生存率高于<1 h组(P<0.05,P<0.01)。结论 感染性休克患者初始液体复苏应在1~2 h内完成,能有效改善器官功能障碍和病情,维持血流动力学水平,加快恢复进程,促进病情良好转归。 展开更多
关键词 休克 脓毒性 液体复苏 完成时限 中心静脉压 血乳酸 动脉血氧分压 去甲肾上腺素 生存率
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改良俯卧位通气在病毒性肺炎清醒患者中的应用效果观察 被引量:1
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作者 张婷婷 姚娜 柳娟娟 《临床误诊误治》 CAS 2024年第5期35-41,共7页
目的观察改良俯卧位通气对病毒性肺炎清醒患者的应用效果。方法选取2022年4月—2023年2月病毒性肺炎清醒患者80例,采用随机数字表法分为2组,每组40例,对照组采取常规俯卧位通气,观察组采取改良俯卧位通气。观察2组康复情况、俯卧位前后... 目的观察改良俯卧位通气对病毒性肺炎清醒患者的应用效果。方法选取2022年4月—2023年2月病毒性肺炎清醒患者80例,采用随机数字表法分为2组,每组40例,对照组采取常规俯卧位通气,观察组采取改良俯卧位通气。观察2组康复情况、俯卧位前后血气指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))、血氧饱和度(SaO_(2))、氧合指数],血流动力学指标[心率(HR)、平均动脉压(MAP)、每搏输出量变异(SVV)、每搏输出量指数(SVI)],呼吸功能指标[气道平均压(Pmean)、气道峰压(Ppeak)、肺动态顺应性(Cydn)],血清核转录因子-κB(NF-κB)变化及压力性损伤情况。结果观察组住院时间短于对照组(P<0.01)。俯卧位1、2、4、8、16 h时2组PaO_(2)、PaCO_(2)、SaO_(2)、氧合指数均较俯卧位前改善,俯卧位24、36 h时2组Pmean、Ppeak、Cydn均较俯卧位前改善,俯卧位24、36 h时血清NF-κB水平均较俯卧位前改善(P<0.05),但2组间比较无差异(P>0.05);2组组间、组内不同时点HR、MAP、SVV、SVI比较均无差异(P>0.05);观察组压力性损伤发生率为2.50%(1/40)低于对照组的20.00%(8/40)(P<0.05)。结论病毒性肺炎清醒患者行改良俯卧位通气可达到与常规俯卧位通气相近的辅助治疗效果,并可提高氧合功能、改善呼吸功能及肺顺应性、减少炎症反应和压力性损伤事件,促进疾病早期康复。 展开更多
关键词 病毒性肺炎 改良俯卧位通气 清醒 压力性损伤 动脉血氧分压 血氧饱和度 平均动脉压 气道峰压
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心脏骤停患者呼气末二氧化碳分压与自主循环恢复关系的研究
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作者 王晓蕾 王秋艳 +4 位作者 于美军 陈静 曾君 李力平 吴双 《中华保健医学杂志》 2024年第2期159-161,共3页
目的探讨心脏骤停(CA)患者呼气末二氧化碳分压(P_(ET)CO_(2))与自主循环恢复(ROSC)的关系研究。方法回顾性选取2018年5月~2023年5月就诊于北京大学第三医院秦皇岛医院急诊科及重症医学科成人CA患者107例的数据。分析CA患者P_(ET)CO_(2)... 目的探讨心脏骤停(CA)患者呼气末二氧化碳分压(P_(ET)CO_(2))与自主循环恢复(ROSC)的关系研究。方法回顾性选取2018年5月~2023年5月就诊于北京大学第三医院秦皇岛医院急诊科及重症医学科成人CA患者107例的数据。分析CA患者P_(ET)CO_(2)水平与ROSC的关系。结果107例CA患者经心肺复苏术(CPR)抢救治疗后,73例患者自主循环恢复设为ROSC组,34例患者复苏失败设为无ROSC组。ROSC组在10、20和30 min时P_(ET)CO_(2)均高于无ROSC组,差异有统计学意义(t=29.457、56.934、51.801,P<0.05)。107例CA患者中共有67例患者存活(存活组),40例患者死亡(死亡组)。两组0 min时P_(ET)CO_(2)差异无统计学意义(t=0.504,P=0.615);存活组在10、20和30 min时P_(ET)CO_(2)均高于死亡组,差异有统计学意义(t=16.955、14.757、17.071,P<0.05);P_(ET)CO_(2)、CA对ROSC造成影响时,标准化路径系数分别为0.182、0.187、0.353,路径呈现出的0.05水平的显著性(Z=2.283、2.340、5.798,P<0.05)。结论CA患者P_(ET)CO_(2)水平与ROSC的关系为正向影响关系,可以监测并预估患者CPR质量。 展开更多
关键词 心脏骤停 呼气末二氧化碳分压 自主循环恢复
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TcPCO_2与TOF指导老年患者全麻术后拔管时机对呼吸系统不良事件发生的影响 被引量:1
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作者 魏晶晶 赵磊 +1 位作者 王天龙 肖玮 《北京医学》 CAS 2016年第6期510-514,共5页
目的探讨经皮组织CO_2分压(transcutaneous partial pressure of carbon dioxide,Tc PCO_2)监测联合四个成串刺激(train-of-four,TOF)监测指导老年患者拔管,对于降低老年患者全麻术后呼吸系统不良事件的临床价值。方法择期全麻手术... 目的探讨经皮组织CO_2分压(transcutaneous partial pressure of carbon dioxide,Tc PCO_2)监测联合四个成串刺激(train-of-four,TOF)监测指导老年患者拔管,对于降低老年患者全麻术后呼吸系统不良事件的临床价值。方法择期全麻手术老年患者(年龄〉65岁),随机分为常规组(C组)、TOF组(T组)、TOF联合Tc PCO_2(U)组。3组患者采用相同的麻醉管理方法。C组根据临床指标常规拔管,T组除达到常规拔管条件外还需满足TOF≥0.9,U组除满足常规拔管条件外,还需同时满足TOF≥0.9且Tc PCO_2恢复至术前基础水平±5 mm Hg。拔管后3组患者均返回麻醉恢复室(postanesthesia care unit,PACU),比较各组患者在拔管即刻、入PACU后即刻、入PACU后30 min、入PACU后60min呼吸系统不良事件的发生率。结果 40例患者纳入本研究,3组患者的一般资料比较,差异无统计学意义(P〉0.05);在拔管即刻,3组患者CO_2蓄积的发生率比较:C组与U组比较差异有统计学意义(66.7%vs.9.1%;χ^2=6.421,P=0.011),其余各个时刻T组与U组CO_2蓄积的发生率均低于C组,但无统计学意义(P〉0.017);与C组相比,T组与U组在各个时刻肌力恢复不佳及主观症状虚弱的发生率均低于C组,且有统计学意义(P〈0.017)。结论联合应用TOF与Tc PCO_2监测老年患者拔管,可以减少老年患者拔管后早期呼吸系统的并发症,提高安全性。 展开更多
关键词 老年患者 经皮组织CO2分压 四个成串刺激 全麻 拔管 呼吸道不良事件
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动脉血二氧化碳分压联合修正版Geneva评分对急性肺栓塞的联合预测效能
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作者 侯俊飞 柴卫芳 黄娜 《四川生理科学杂志》 2024年第2期378-380,425,共4页
目的:探讨动脉血二氧化碳分压(Partial pressure of carbon dioxide,PaCO_(2))联合修正版Geneva评分对急性肺栓塞(Pulmonary embolism,APE)的联合预测效能。方法:回顾性分析2019年1月至2022年12月于我院进行治疗的疑似急性肺栓塞患者的... 目的:探讨动脉血二氧化碳分压(Partial pressure of carbon dioxide,PaCO_(2))联合修正版Geneva评分对急性肺栓塞(Pulmonary embolism,APE)的联合预测效能。方法:回顾性分析2019年1月至2022年12月于我院进行治疗的疑似急性肺栓塞患者的临床资料265例。据计算机断层扫描肺血管造影术(Computed tomography pulmonary angiography,CTPA)检查结果将265例患者分为APE组(CPTA阳性)与Non-APE组(CPTA阴性),其中APE组138例,Non-APE组127例。收集并对比两组患者的临床资料,并分析PaCO_(2)联合修正版Geneva评分的联合预测效能。结果:APE组与Non-APE组患者的呼吸困难、咳血、晕厥、胸痛症状分布差异无统计学意义。APE组患者修正版Geneva评分分布明显高于Non-APE组(P<0.05);APE组PaCO_(2)<35 mmHg的患者明显多于Non-APE组(P<0.05)。PaCO_(2)联合修正版Geneva评分对于急性肺栓塞预测的曲线下面积(Area Under Curve,AUC)、95%CI高于单独指标。结论:PaCO_(2)联合修正版Geneva评分预测急性肺栓塞的曲线下面积显著高于单一指标,其敏感度显著优于单独修正版Geneva评分系统,特异度优于PaCO_(2)。 展开更多
关键词 动脉血二氧化碳分压 修正版Geneva 急性肺栓塞 预测效能
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血清CTRP3、BMP-7及PetCO_(2)对呼吸窘迫综合征患儿机械通气撤机的预测价值
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作者 王楠 车晓晴 +1 位作者 王浩然 刘卫平 《医学检验与临床》 2024年第8期10-14,38,共6页
目的:探讨新生儿呼吸窘迫综合征(NRDS)血清补体C1q-肿瘤坏死因子相关蛋白3(CTRP3)、骨形态发生蛋白-7(BMP-7)及呼吸末二氧化碳分压(PetCO_(2))对机械通气撤机的预测价值。方法:选取80例NRDS患儿为研究对象,依据撤机结局分为成功组54例... 目的:探讨新生儿呼吸窘迫综合征(NRDS)血清补体C1q-肿瘤坏死因子相关蛋白3(CTRP3)、骨形态发生蛋白-7(BMP-7)及呼吸末二氧化碳分压(PetCO_(2))对机械通气撤机的预测价值。方法:选取80例NRDS患儿为研究对象,依据撤机结局分为成功组54例、失败组26例。比较2组基线资料。分析不同组、不同严重程度患儿PetCO_(2)、血清CTRP3、BMP-7水平,分析其与生化指标、疾病严重程度相关性。评价PetCO_(2)、血清CTRP3、BMP-7对撤机结局的预测价值。采用SPSS24.0对数据进行分析,计数资料采用χ^(2)检验,计量资料采用t检验。结果:治疗12h、24h后成功组PetCO_(2)分别为(36.32±1.88)(mmHg)4、(33.06±1.79)(mmHg)4,血清BMP-7水平分别为(44.03±5.17)pg/mL、(41.16±4.88)pg/mL,血清℃TRP3水平分别为(345.59±60.03)μg/L、(377.41±75.80)μg/L;治疗12h、24h后失败组PetCO_(2),分别为(38.62±1.93)(mmHg)4、(38.57±1.90)(mmHg)4,血清BMP-7水平分别为(48.82±5.96)pg/mL、(48.39±5.63)pg/mL,血清CTRP3水平分别为(316.68±55.56)μg/L、(320.03±66.67)μg/L,治疗12h、24h后成功组PetCO_(2)、血清BMP-7水平低于失败组,血清CTRP3水平高于失败组(P<0.05);PetCO_(2)、BMP-7与PaO_(2)呈负相关,且与PaCO_(2)、SNAPPE-ⅡI评分、TGF-β1、IL-6、TNF-α、病情严重程度呈正相关,而CTRP3与之相反(P<0.05);治疗12h、24h后血清CTRP3、BMP-7及PetCO_(2),联合预测撤机结局的AUC大于单项预测(P<0.05)。结论:血清CTRP3、BMP-7及PetCO_(2),对NRDS患儿撤机结局预测具有应用价值。 展开更多
关键词 新生儿呼吸窘迫综合征 补体C1q-肿瘤坏死因子相关蛋白3 骨形态发生蛋白-7 呼吸末二氧化碳分压
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