We present a formulation of the single-trajectory entropy using the trajectories ensemble. The single-trajectory entropy is affected by its surrounding trajectories via the distribution function. The single-trajectory...We present a formulation of the single-trajectory entropy using the trajectories ensemble. The single-trajectory entropy is affected by its surrounding trajectories via the distribution function. The single-trajectory entropies are studied in two typical potentials, i.e., harmonic potential and double-well potential, and in viscous environment by interacting trajectory method. The results of the trajectory methods are in agreement well with the numerical methods(Monte Carlo simulation and difference equation). The single-trajectory entropies increasing(decreasing) could be caused by absorption(emission) heat from(to) the thermal environment. Also, some interesting trajectories, which correspond to the rare evens in the processes, are demonstrated.展开更多
BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution.Despite its clinical utility,the TSF thickness trajectories and their correlatio...BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution.Despite its clinical utility,the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly investigated.AIM To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause mortality.METHODS This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition Survey.Latent class trajectory modeling was employed to identify distinct trajectories of TSF thickness.Subjects were classified into subgroups reflective of their respective TSF thickness trajectory.We utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality,including contributory factors.RESULTS Upon adjustment for multiple confounding factors,we discerned that males in the‘Class 2:Thin-stable’and‘Class 3:Thin-moderate’TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the‘Class 1:Extremely thin’subgroup.In the mediation analyses,the Geriatric Nutritional Risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and mortality.For females,a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly cohort.CONCLUSION In males and non-elderly females,lower TSF thickness trajectories are significantly predictive of heightened mortality risk,independent of single-point TSF thickness,body mass index,and waist circumference.展开更多
Background Increasing resilience is a priority in modern pig breeding.Recent research shows that general resilience can be quantified via variability in longitudinal data.The collection of such longitudinal data on we...Background Increasing resilience is a priority in modern pig breeding.Recent research shows that general resilience can be quantified via variability in longitudinal data.The collection of such longitudinal data on weight,feed intake and feeding behaviour in pigs has been facilitated by the development of technologies such as automated feeding stations.The goal of this study was to investigate resilience traits,which were estimated as deviations from longitudinal weight,feed intake and feeding behaviour data during the finishing phase.A dataset with 324,207 records between the age of 95 and 155 days on 5,939 Pietrain pigs with known pedigree and genomic information was used.We provided guidelines for a rigid quality control of longitudinal body weight data,as we found that outliers can significantly affect results.Gompertz growth curve analysis,linear modelling and trajectory analyses were used for quantifying resilience traits.Results To our knowledge,this is the first study comparing resilience traits from longitudinal body weight,feed intake and feeding behaviour data in pigs.We demonstrated that the resilience traits are lowly to moderately heritable for deviations in body weight(h2=2.9%–20.2%),in feed intake(9.4%–23.3%)and in feeding behaviour(16.2%–28.3%).Additionally,these traits have good predictive abilities in cross-validation analyses.Deviations in individual body weight and feed intake trajectories are highly correlated(rg=0.78)with low to moderate favourable genetic correlations with feed conversion ratio(rg=0.39–0.49).Lastly,we showed that some resilience traits,such as the natural logarithm of variances of observed versus predicted body weights(lnvarweight),are more robust to lower observation frequencies and are repeatable over three different time periods of the finishing phase.Conclusions Our results will help future studies investigating resilience traits and resilience-related traits.Moreover,our study provides first results on standardization of quality control and efficient data sampling from automated feeding station data.Our findings will be valuable for breeding organizations as they offer evidence that pigs’general resilience can be selected on with good accuracy.Moreover,this methodology might be extended to other species to quantify resilience based on longitudinal data.展开更多
The growth trajectory of hailstones in clouds determines the ground intensity and spatial distribution of hailfall.A systematic study of hail trajectories can help improve the current scientific understanding of the m...The growth trajectory of hailstones in clouds determines the ground intensity and spatial distribution of hailfall.A systematic study of hail trajectories can help improve the current scientific understanding of the mechanisms by which hail forms in semi-arid regions of China and,in doing so,improve the quality of hail forecasts and warnings and help to prevent and mitigate disasters.In this study,the WRFv3.7.1 model was employed to provide the background field to drive the hailstone trajectory model.Cluster analysis was then used to classify hail trajectories to investigate the characteristics of different types of hail trajectories and the microphysical characteristics of hail formation.The differences in hail trajectories might be mainly due to differences in the background flow fields and microphysical fields of hail clouds in different regions.Comparative analysis revealed that as the maximum particle size of ground hailfall increased,the maximum supercooled cloud water content and the maximum updraft velocity for the formation and growth of hailstone increased.The larger the size when the hailstone reaches its maximum height,the larger the ground hailstone formed.Overall,the formation and growth of hailstone are caused by the joint action of the dynamical flow field and cloud microphysical processes.The physical processes of hailstone growth and main growth regions differ for different types of hail trajectories.Therefore,different catalytic schemes should be adopted in artificial hail prevention operations for different hail clouds and trajectories due to differences in hail formation processes and ground hailfall characteristics.展开更多
An increase in car ownership brings convenience to people’s life.However,it also leads to frequent traffic accidents.Precisely forecasting surrounding agents’future trajectories could effectively decrease vehicle-ve...An increase in car ownership brings convenience to people’s life.However,it also leads to frequent traffic accidents.Precisely forecasting surrounding agents’future trajectories could effectively decrease vehicle-vehicle and vehicle-pedestrian collisions.Long-short-term memory(LSTM)network is often used for vehicle trajectory prediction,but it has some shortages such as gradient explosion and low efficiency.A trajectory prediction method based on an improved Transformer network is proposed to forecast agents’future trajectories in a complex traffic environment.It realizes the transformation from sequential step processing of LSTM to parallel processing of Transformer based on attentionmechanism.To performtrajectory predictionmore efficiently,a probabilistic sparse self-attention mechanism is introduced to reduce attention complexity by reducing the number of queried values in the attention mechanism.Activate or not(ACON)activation function is adopted to select whether to activate or not,hence improving model flexibility.The proposed method is evaluated on the publicly available benchmarks nextgeneration simulation(NGSIM)and ETH/UCY.The experimental results indicate that the proposed method can accurately and efficiently predict agents’trajectories.展开更多
Objectives:This study was to longitudinally investigate the association between occupational change trajectories and mental health in the Korean population aged 45 years and older from the Korean Longitudinal Study of...Objectives:This study was to longitudinally investigate the association between occupational change trajectories and mental health in the Korean population aged 45 years and older from the Korean Longitudinal Study of Aging(KLo-SA).Methods:After excluding missing values,the data of 6,224 participants from thefirst to eighth waves of the KLo-SA were analyzed using t-test,Analysis of variance(ANOVA),Group-based Trajectory Model(GBTM)from 1–5th KLoSA and Time-Lagged Generalized estimating equation(GEE)model from 5–8th KLoSA to analyze the association between occupational change trajectories and mental health in the Korean population aged 45 years and older.Results:An analysis of the association between occupational change trajectories and mental health demonstrated that,among all age group,the“sustained in unemployment”group had a worse MMSE and CESD score compared to“sustained WC”group.unlike the under-54 age group,those aged≥55 years demonstrated reductions in the MMSE and CESD scores in the sustained unemployment and the changed working condition from Standard BC to Unemployment groups,whereas those who underwent a change from the Standard WC to unemployment group only demonstrated a reduction in MMSE scores.Conclusions:There was a close relationship between occupational change trajectories and mental health.Therefore,this study can serve as the foundation for policies and institutional measures to manage the deteriorate mental health in the late middle-aged and older population.展开更多
Background: Workplace violence (WV) towards psychiatric staff has commonly been associated with Posttraumatic Stress Disorder (PTSD). However, prospective studies have shown that not all psychiatric staff who experien...Background: Workplace violence (WV) towards psychiatric staff has commonly been associated with Posttraumatic Stress Disorder (PTSD). However, prospective studies have shown that not all psychiatric staff who experience workplace violence experience post-traumatic stress. Purpose: We want to examine the longitudinal trajectories of PTSD in this population to identify possible subgroups that might be more at risk. Furthermore, we need to investigate whether certain risk factors of PTSD might identify membership in the subgroups. Method: In a sample of psychiatric staff from 18 psychiatric wards in Denmark who had reported an incident of WV, we used Latent Growth Mixture Modelling (LGMM) and further logistic regression analysis to investigate this. Results: We found three separate PTSD trajectories: a recovering, a delayed-onset, and a moderate-stable trajectory. Higher social support and negative cognitive appraisals about oneself, the world and self-blame predicted membership in the delayed-onset trajectory, while higher social support and lower accept coping predicted membership in the delayed-onset trajectory. Conclusion: Although most psychiatric staff go through a natural recovery, it is important to be aware of and identify staff members who might be struggling long-term. More focus on the factors that might predict these groups should be an important task for psychiatric departments to prevent posttraumatic symptomatology from work.展开更多
为定量识别城市非信控环形交叉口区域内的机动车冲突风险易发生点,降低环形交叉口的事故发生率,本文构建针对非信控环形交叉口机动车冲突风险识别模型。首先,利用无人机采集高精度、连续的多车辆轨迹视频,结合Kinovea视频运动分析软件...为定量识别城市非信控环形交叉口区域内的机动车冲突风险易发生点,降低环形交叉口的事故发生率,本文构建针对非信控环形交叉口机动车冲突风险识别模型。首先,利用无人机采集高精度、连续的多车辆轨迹视频,结合Kinovea视频运动分析软件实现运行车辆状态识别与跟踪,并记录车辆每一帧的运动数据;其次,基于交通冲突识别指标TTC(Time to Collision),提出适应环形交叉口道路线形特征的车辆TTC计算方法,并使用累计频率法确定严重、一般和轻微冲突的阈值分别为1.2,2.8,4.4 s;最后,通过绘制高峰和平峰交通冲突空间异步图,并结合交通冲突数和严重冲突率,对环形交叉口的36个子区段进行交通冲突风险等级评定。研究结果显示:在高峰时段,某一子区段的平均交通冲突发生次数约为15次,严重冲突率为17.45%;在平峰时段,某一子区段的平均交通冲突发生次数约为8次,严重冲突率为8.28%。重度风险区域在高峰时段占比达到50%,而在平峰时段为8.33%,这些重度风险区域主要集中在交织区段。因此,环形交叉口在高峰时段且位于交织区段的情况更易发生交通事故。本文研究成果有助于交通管理部门了解环形交叉口在不同时段和区段上的交通冲突情况和特征,以便采取相应的预警和管理措施。展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 12234013)the Natural Science Foundation of Shandong Province (Grant No. ZR2021LLZ009)。
文摘We present a formulation of the single-trajectory entropy using the trajectories ensemble. The single-trajectory entropy is affected by its surrounding trajectories via the distribution function. The single-trajectory entropies are studied in two typical potentials, i.e., harmonic potential and double-well potential, and in viscous environment by interacting trajectory method. The results of the trajectory methods are in agreement well with the numerical methods(Monte Carlo simulation and difference equation). The single-trajectory entropies increasing(decreasing) could be caused by absorption(emission) heat from(to) the thermal environment. Also, some interesting trajectories, which correspond to the rare evens in the processes, are demonstrated.
基金Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-015CAMS Innovation Fund for Medical Sciences,No.2021-1-12M-002+1 种基金CAMS Innovation Fund for Medical Sciences,No.2023-I2M-C&T-B-043Beijing Municipal Natural Science Foundation,No.M22014.
文摘BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution.Despite its clinical utility,the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly investigated.AIM To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause mortality.METHODS This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition Survey.Latent class trajectory modeling was employed to identify distinct trajectories of TSF thickness.Subjects were classified into subgroups reflective of their respective TSF thickness trajectory.We utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality,including contributory factors.RESULTS Upon adjustment for multiple confounding factors,we discerned that males in the‘Class 2:Thin-stable’and‘Class 3:Thin-moderate’TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the‘Class 1:Extremely thin’subgroup.In the mediation analyses,the Geriatric Nutritional Risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and mortality.For females,a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly cohort.CONCLUSION In males and non-elderly females,lower TSF thickness trajectories are significantly predictive of heightened mortality risk,independent of single-point TSF thickness,body mass index,and waist circumference.
基金This study was partially funded by an FR PhD fellowship(1104320N,WG)two SB PhD fellowships(1S05818N(CW)and 1S37119N(RM))of the Research Foundation Flanders(FWO)+1 种基金Moreover,RM and LC were also partly funded by a KU Leuven C2 project(C24/18/036)KH was funded by the UNIPIG project of VLAIO(HBC.2019.2866).
文摘Background Increasing resilience is a priority in modern pig breeding.Recent research shows that general resilience can be quantified via variability in longitudinal data.The collection of such longitudinal data on weight,feed intake and feeding behaviour in pigs has been facilitated by the development of technologies such as automated feeding stations.The goal of this study was to investigate resilience traits,which were estimated as deviations from longitudinal weight,feed intake and feeding behaviour data during the finishing phase.A dataset with 324,207 records between the age of 95 and 155 days on 5,939 Pietrain pigs with known pedigree and genomic information was used.We provided guidelines for a rigid quality control of longitudinal body weight data,as we found that outliers can significantly affect results.Gompertz growth curve analysis,linear modelling and trajectory analyses were used for quantifying resilience traits.Results To our knowledge,this is the first study comparing resilience traits from longitudinal body weight,feed intake and feeding behaviour data in pigs.We demonstrated that the resilience traits are lowly to moderately heritable for deviations in body weight(h2=2.9%–20.2%),in feed intake(9.4%–23.3%)and in feeding behaviour(16.2%–28.3%).Additionally,these traits have good predictive abilities in cross-validation analyses.Deviations in individual body weight and feed intake trajectories are highly correlated(rg=0.78)with low to moderate favourable genetic correlations with feed conversion ratio(rg=0.39–0.49).Lastly,we showed that some resilience traits,such as the natural logarithm of variances of observed versus predicted body weights(lnvarweight),are more robust to lower observation frequencies and are repeatable over three different time periods of the finishing phase.Conclusions Our results will help future studies investigating resilience traits and resilience-related traits.Moreover,our study provides first results on standardization of quality control and efficient data sampling from automated feeding station data.Our findings will be valuable for breeding organizations as they offer evidence that pigs’general resilience can be selected on with good accuracy.Moreover,this methodology might be extended to other species to quantify resilience based on longitudinal data.
基金supported by the National Natural Science Foundation of China (Grant Nos. 41975176, 42061134009)the High Performance Computing Center of Nanjing University of Information Science and Technology for their support of this work
文摘The growth trajectory of hailstones in clouds determines the ground intensity and spatial distribution of hailfall.A systematic study of hail trajectories can help improve the current scientific understanding of the mechanisms by which hail forms in semi-arid regions of China and,in doing so,improve the quality of hail forecasts and warnings and help to prevent and mitigate disasters.In this study,the WRFv3.7.1 model was employed to provide the background field to drive the hailstone trajectory model.Cluster analysis was then used to classify hail trajectories to investigate the characteristics of different types of hail trajectories and the microphysical characteristics of hail formation.The differences in hail trajectories might be mainly due to differences in the background flow fields and microphysical fields of hail clouds in different regions.Comparative analysis revealed that as the maximum particle size of ground hailfall increased,the maximum supercooled cloud water content and the maximum updraft velocity for the formation and growth of hailstone increased.The larger the size when the hailstone reaches its maximum height,the larger the ground hailstone formed.Overall,the formation and growth of hailstone are caused by the joint action of the dynamical flow field and cloud microphysical processes.The physical processes of hailstone growth and main growth regions differ for different types of hail trajectories.Therefore,different catalytic schemes should be adopted in artificial hail prevention operations for different hail clouds and trajectories due to differences in hail formation processes and ground hailfall characteristics.
基金the SuzhouKey industrial technology innovation project SYG202031the Future Network Scientific Research Fund Project,FNSRFP-2021-YB-29.
文摘An increase in car ownership brings convenience to people’s life.However,it also leads to frequent traffic accidents.Precisely forecasting surrounding agents’future trajectories could effectively decrease vehicle-vehicle and vehicle-pedestrian collisions.Long-short-term memory(LSTM)network is often used for vehicle trajectory prediction,but it has some shortages such as gradient explosion and low efficiency.A trajectory prediction method based on an improved Transformer network is proposed to forecast agents’future trajectories in a complex traffic environment.It realizes the transformation from sequential step processing of LSTM to parallel processing of Transformer based on attentionmechanism.To performtrajectory predictionmore efficiently,a probabilistic sparse self-attention mechanism is introduced to reduce attention complexity by reducing the number of queried values in the attention mechanism.Activate or not(ACON)activation function is adopted to select whether to activate or not,hence improving model flexibility.The proposed method is evaluated on the publicly available benchmarks nextgeneration simulation(NGSIM)and ETH/UCY.The experimental results indicate that the proposed method can accurately and efficiently predict agents’trajectories.
文摘Objectives:This study was to longitudinally investigate the association between occupational change trajectories and mental health in the Korean population aged 45 years and older from the Korean Longitudinal Study of Aging(KLo-SA).Methods:After excluding missing values,the data of 6,224 participants from thefirst to eighth waves of the KLo-SA were analyzed using t-test,Analysis of variance(ANOVA),Group-based Trajectory Model(GBTM)from 1–5th KLoSA and Time-Lagged Generalized estimating equation(GEE)model from 5–8th KLoSA to analyze the association between occupational change trajectories and mental health in the Korean population aged 45 years and older.Results:An analysis of the association between occupational change trajectories and mental health demonstrated that,among all age group,the“sustained in unemployment”group had a worse MMSE and CESD score compared to“sustained WC”group.unlike the under-54 age group,those aged≥55 years demonstrated reductions in the MMSE and CESD scores in the sustained unemployment and the changed working condition from Standard BC to Unemployment groups,whereas those who underwent a change from the Standard WC to unemployment group only demonstrated a reduction in MMSE scores.Conclusions:There was a close relationship between occupational change trajectories and mental health.Therefore,this study can serve as the foundation for policies and institutional measures to manage the deteriorate mental health in the late middle-aged and older population.
文摘Background: Workplace violence (WV) towards psychiatric staff has commonly been associated with Posttraumatic Stress Disorder (PTSD). However, prospective studies have shown that not all psychiatric staff who experience workplace violence experience post-traumatic stress. Purpose: We want to examine the longitudinal trajectories of PTSD in this population to identify possible subgroups that might be more at risk. Furthermore, we need to investigate whether certain risk factors of PTSD might identify membership in the subgroups. Method: In a sample of psychiatric staff from 18 psychiatric wards in Denmark who had reported an incident of WV, we used Latent Growth Mixture Modelling (LGMM) and further logistic regression analysis to investigate this. Results: We found three separate PTSD trajectories: a recovering, a delayed-onset, and a moderate-stable trajectory. Higher social support and negative cognitive appraisals about oneself, the world and self-blame predicted membership in the delayed-onset trajectory, while higher social support and lower accept coping predicted membership in the delayed-onset trajectory. Conclusion: Although most psychiatric staff go through a natural recovery, it is important to be aware of and identify staff members who might be struggling long-term. More focus on the factors that might predict these groups should be an important task for psychiatric departments to prevent posttraumatic symptomatology from work.
文摘为定量识别城市非信控环形交叉口区域内的机动车冲突风险易发生点,降低环形交叉口的事故发生率,本文构建针对非信控环形交叉口机动车冲突风险识别模型。首先,利用无人机采集高精度、连续的多车辆轨迹视频,结合Kinovea视频运动分析软件实现运行车辆状态识别与跟踪,并记录车辆每一帧的运动数据;其次,基于交通冲突识别指标TTC(Time to Collision),提出适应环形交叉口道路线形特征的车辆TTC计算方法,并使用累计频率法确定严重、一般和轻微冲突的阈值分别为1.2,2.8,4.4 s;最后,通过绘制高峰和平峰交通冲突空间异步图,并结合交通冲突数和严重冲突率,对环形交叉口的36个子区段进行交通冲突风险等级评定。研究结果显示:在高峰时段,某一子区段的平均交通冲突发生次数约为15次,严重冲突率为17.45%;在平峰时段,某一子区段的平均交通冲突发生次数约为8次,严重冲突率为8.28%。重度风险区域在高峰时段占比达到50%,而在平峰时段为8.33%,这些重度风险区域主要集中在交织区段。因此,环形交叉口在高峰时段且位于交织区段的情况更易发生交通事故。本文研究成果有助于交通管理部门了解环形交叉口在不同时段和区段上的交通冲突情况和特征,以便采取相应的预警和管理措施。