Field reversed configuration(FRC)is widely considered as an ideal target plasma for magnetoinertial fusion.However,its confinement and stability,both proportional to the radius,will deteriorate inevitably during radia...Field reversed configuration(FRC)is widely considered as an ideal target plasma for magnetoinertial fusion.However,its confinement and stability,both proportional to the radius,will deteriorate inevitably during radial compression.Hence,we propose a new fusion approach based on axial compression of a large-sized FRC.The axial compression can be made by plasma jets or plasmoids converging onto the axial ends of the FRC.The parameter space that can reach the ignition condition while preserving the FRC's overall quality is studied using a numerical model based on different FRC confinement scalings.It is found that ignition is possible for a large FRC that can be achieved with the current FRC formation techniques if compression ratio is greater than 50.A more realistic compression is to combine axial with moderate radial compression,which is also presented and calculated in this work.展开更多
This study aims to improve the performances of the high-pressure water descaling technology used in steel hot rolling processes.In particular,a 2050 mm hot rolling line is considered,and the problem is investigated by...This study aims to improve the performances of the high-pressure water descaling technology used in steel hot rolling processes.In particular,a 2050 mm hot rolling line is considered,and the problem is investigated by means of a fluid–structure interaction(FSI)method by which the descaling effect produced by rolling coils with different section sizes is examined.Assuming a flat fan-shaped nozzle at the entrance of the R1R2 roughing mill,the outflow field characteristics and the velocity distribution curve on the strike line(at a target distance of 30–120 mm)are determined.It is found that the velocity in the center region of the water jet with different target distances is higher than that in the boundary region.As the target distance increases,the velocity of the water jet in the central region decreases.Through comparison with experimental results,it is shown that the simulation model can accurately predict the impact position of the high-pressure water on the impact plate,thereby providing a computational scheme that can be used to optimize the nozzle space layout and improve the slabs’descent effect for different rolling specifications.展开更多
Interaction between high-intensity pulsed ion beam (HIPIB) and a double-layer target with titanium film on top of aluminum substrate was simulated. The two-dimensional nonlinear thermal conduction equations, with th...Interaction between high-intensity pulsed ion beam (HIPIB) and a double-layer target with titanium film on top of aluminum substrate was simulated. The two-dimensional nonlinear thermal conduction equations, with the deposited energy in the target taken as source term, were derived and solved by finite differential method. As a result, the two-dimensional spatial and temporal evolution profiles of temperature were obtained for a titanium/aluminum double-layer target irradiated by a pulse of HIPIB. The effects of ion beam current density on the phase state of the target materials near the film and substrate interface were analyzed. Both titanium and aluminum were melted near the interface after a shot when the ion beam current density fell in the range of 100 A/cm2 to 200 A/cm2.展开更多
Objective: To evaluate the effect of magnetic nanoparticle containing 5-fluorouracil (5-FU) targeting in treating chol- angiocarcinoma based on internal magnetic fields built inside the tumor. Methods: 32 nude mice of...Objective: To evaluate the effect of magnetic nanoparticle containing 5-fluorouracil (5-FU) targeting in treating chol- angiocarcinoma based on internal magnetic fields built inside the tumor. Methods: 32 nude mice of BABL/C bearing ectopic tumor were built by subcutaneouly injecting cholangiocarcinoma cell line QBC 939. Three weeks after tumor inoculation, the animal models were divided equally into four groups at random including: (a) group A, consisting of internal magnetic field built by magnetic biliary stent wires inserted into tumor tissue and receiving magnetic nanoparticles containing 5-FU administered via tail vein injection at 250 mg/kg for consecutive five days; (b) group B, receiving placebo (sodium chloride); (c) group C, receiving pure magnetic biliary stent wires without the applying of magnetic nanoparticles; (d) group D, consisting of external magnetic fields and the same treatment of magnetic nanoparticles containing 5-FU as group A. The tumor volumes were measured every 3 days, totally six times from treatment started. Tumor tissues were observed by transmission electron microscope when the nude mice were killed after the observation period. Results: The experimental group (group A) showed significantly therapeutic efficacy. Moreover, apoptosis of tumor cells could be easily detected in this group. Conclusion: Magnetic particles containing 5-FU combined with internal magnetic field can effectively treat cholangiocarcinoma, and its therapeutic efficacy is better than that of the traditional method based on external magnetic fields.展开更多
Recently generation of strong magnetic(B)fields has been demonstrated in capacitor coils heated by high power laser pulses[S.Fujioka et al.,Sci.Rep.3,1170(2013)].This paper will present a direct measurement of B field...Recently generation of strong magnetic(B)fields has been demonstrated in capacitor coils heated by high power laser pulses[S.Fujioka et al.,Sci.Rep.3,1170(2013)].This paper will present a direct measurement of B field generated with an open-ended coil target driven by a nanosecond laser pulse using ultrafast proton radiography.The radiographs are analyzed with particle-tracing simulations.The B field at the coil center is inferred to be ~50 T at an irradiance of ~5×10^(14) W·cm^(-2).The B field generation is attributed to the background cold electron flow pointing to the laser focal spot,where a target potential is induced due to the escape of energetic electrons.展开更多
Nanoparticle-mediated drug delivery is recognized as a promising option for targeted treatment of atherosclerosis. In this paper, the Eulerian-Lagrangian technique is adopted to simulate the delivery of drug-loaded na...Nanoparticle-mediated drug delivery is recognized as a promising option for targeted treatment of atherosclerosis. In this paper, the Eulerian-Lagrangian technique is adopted to simulate the delivery of drug-loaded nanoparticles to patient-specific atherosclerotic plaque with the aid of an external magnetic field. Plaques and vascular walls are introduced as porous media formulated by the Darcy-Forchheimer model in this targeted transport process. The results demonstrate that the delivery efficiency of particles to atherosclerosis depends on the external magnetic field, such as configuration and intensity, in which the configuration angle of the current wire is a key factor and the double current wires have advantages over the single current wire. Meanwhile, the delivery efficiency gradually decreases as the distance between the plaque cap and the current wire increases. Further, although augmenting the current or magnetic susceptibility can generally improve the delivery efficiency of nanoparticles, this increase is not apparent when small-sized nanoparticles are employed as drug transport particles. The results obtained can potentially serve as the guideline to optimize regimens for the targeted therapy of atherosclerosis.展开更多
A novel robot navigation algorithm with global path generation capability is presented. Local minimum is a most intractable but is an encountered frequently problem in potential field based robot navigation.Through ap...A novel robot navigation algorithm with global path generation capability is presented. Local minimum is a most intractable but is an encountered frequently problem in potential field based robot navigation.Through appointing appropriately some virtual local targets on the journey, it can be solved effectively. The key concept employed in this algorithm are the rules that govern when and how to appoint these virtual local targets. When the robot finds itself in danger of local minimum, a virtual local target is appointed to replace the global goal temporarily according to the rules. After the virtual target is reached, the robot continues on its journey by heading towards the global goal. The algorithm prevents the robot from running into local minima anymore. Simulation results showed that it is very effective in complex obstacle environments.展开更多
In the initial phase of the physics experiment, the double-null divertor plates used consist of graphite armor tiles, Mo-alloy intermediate layers and Cu-alloy coolant tubes. In the later operating phase, tungsten wil...In the initial phase of the physics experiment, the double-null divertor plates used consist of graphite armor tiles, Mo-alloy intermediate layers and Cu-alloy coolant tubes. In the later operating phase, tungsten will be used as armor tiles. A multi-physical field numerical analysis method is used in this paper. Its analysis model reflects more realistically the real divertor structure than other models. Two-dimensional (2D) and three-dimensional (3D) fluid flow field, temperature distribution and thermal stress analyses of the divertor plates are carried out by the ANSYS code. During the physics experimental phase with a heat flux of 1 MW/m2, a coolant velocity of 5.48 m/s, and a thermal stress of 750 kg/cm2, the graphite armor tiles successfully meet the requirements of temperature, thermal stress and sputtering erosion. The tungsten armor will be considered as a second candidate. The result of simulation can be used for upgrading the design parameters of the HL-2A poloidal divertor.展开更多
Valuable dropsonde data were obtained from multiple field campaigns targeting tropical cyclones,namely Higos,Nangka,Saudel,and Atsani,over the western North Pacific by the Hong Kong Observatory and Taiwan Central Weat...Valuable dropsonde data were obtained from multiple field campaigns targeting tropical cyclones,namely Higos,Nangka,Saudel,and Atsani,over the western North Pacific by the Hong Kong Observatory and Taiwan Central Weather Bureau in 2020.The conditional nonlinear optimal perturbation(CNOP)method has been utilized in real-time to identify the sensitive regions for targeting observations adhering to the procedure of real-time field campaigns for the first time.The observing system experiments were conducted to evaluate the effect of dropsonde data and CNOP sensitivity on TC forecasts in terms of track and intensity,using the Weather Research and Forecasting model.It is shown that the impact of assimilating all dropsonde data on both track and intensity forecasts is case-dependent.However,assimilation using only the dropsonde data inside the sensitive regions displays unanimously positive effects on both the track and intensity forecast,either of which obtains comparable benefits to or greatly reduces deterioration of the skill when assimilating all dropsonde data.Therefore,these results encourage us to further carry out targeting observations for the forecast of tropical cyclones according to CNOP sensitivity.展开更多
A novel modified four path method (FPM) is presented for calculating coupling field of super-low altitude aircraft target. Based on the hybrid method PO + MEC (Physical Optics and Method of Equivalent Currents), the a...A novel modified four path method (FPM) is presented for calculating coupling field of super-low altitude aircraft target. Based on the hybrid method PO + MEC (Physical Optics and Method of Equivalent Currents), the antenna radiation pattern is introduced to consider the multipath interference from side lobe of seeker. The modified FPM is used to calculate the coupling field from super-low altitude aircraft target above different terrestrial environments. The curves of scattering coefficient are analyzed. The influences of height of target, root mean square (RMS), and incident angle on coupling field characteristics are discussed. The simulation results can be used for reference in detection for super-low altitude target and optimization for radar system.展开更多
The automatic identification of underwater noncooperative targets without label records remains an arduous task considering the marine noise interference and the shortage of labeled samples.In particular,the data-driv...The automatic identification of underwater noncooperative targets without label records remains an arduous task considering the marine noise interference and the shortage of labeled samples.In particular,the data-driven mechanism of deep learning cannot identify false samples,aggravating the difficulty in noncooperative underwater target recognition.A semi-supervised ensemble framework based on vertical line array fusion and the sparse adversarial co-training algorithm is proposed to identify noncooperative targets effectively.The sound field cross-correlation compression(SCC)feature is developed to reduce noise and computational redundancy.Starting from an incomplete dataset,a joint adversarial autoencoder is constructed to extract the sparse features with source depth sensitivity,aiming to discover the unknown underwater targets.The adversarial prediction label is converted to initialize the joint co-forest,whose evaluation function is optimized by introducing adaptive confidence.The experiments prove the strong denoising performance,low mean square error,and high separability of SCC features.Compared with several state-of-the-art approaches,the numerical results illustrate the superiorities of the proposed method due to feature compression,secondary recognition,and decision fusion.展开更多
For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve ...For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve this problem,a calibration method based on flexible planar target is proposed.In this method,distortion factor is firstly acquired by the invariance of cross ratio,and existing feature points are adjusted with the distortion factor.Then,a large number of points that will be used for the calibration are constructed with the adjusted feature points.Simultaneously,Tsai method is modified so as to reduce the complexity of calibration,which makes the process linear.The simulation and real experiments show that the method proposed in this paper is simple,linear,accurate and robust,and the precision of this method is close to that of Tsai method using abundant points.The method can satisfy the requirement of high precision calibration for camera with large field-of-view.展开更多
针对无人机复杂环境下的全局航迹规划问题,将人工势场法与双向RRTs(Rapidly-exploring random trees)算法结合,提出一种改进双向RRTs算法。首先,目标偏置策略引导采样点以一定概率顺着目标点生成,同时随机树新节点受到障碍物斥力和目标...针对无人机复杂环境下的全局航迹规划问题,将人工势场法与双向RRTs(Rapidly-exploring random trees)算法结合,提出一种改进双向RRTs算法。首先,目标偏置策略引导采样点以一定概率顺着目标点生成,同时随机树新节点受到障碍物斥力和目标点引力的合力影响有效避开障碍物生长,提高航迹搜寻效率,其次对随机树的节点扩展考虑了无人机飞行性能约束条件,最后采用3阶贝塞尔函数进一步航迹优化。仿真结果表明:二维和三维复杂环境中改进双向RRTs算法相比传统RRT、双向RRTs算法航迹搜索耗时减少了71.3%、24.7%和41.0%、18.6%,验证了改进算法全局搜索能力的快速性和有效性,能很好的应用于无人机离线全局航迹规划场合。展开更多
基金supported by National Natural Science Foundation of China(No.12175226)。
文摘Field reversed configuration(FRC)is widely considered as an ideal target plasma for magnetoinertial fusion.However,its confinement and stability,both proportional to the radius,will deteriorate inevitably during radial compression.Hence,we propose a new fusion approach based on axial compression of a large-sized FRC.The axial compression can be made by plasma jets or plasmoids converging onto the axial ends of the FRC.The parameter space that can reach the ignition condition while preserving the FRC's overall quality is studied using a numerical model based on different FRC confinement scalings.It is found that ignition is possible for a large FRC that can be achieved with the current FRC formation techniques if compression ratio is greater than 50.A more realistic compression is to combine axial with moderate radial compression,which is also presented and calculated in this work.
基金The research was funded by Science and Technology Project of Hebei Education Department(Project Number:QN2022198).Y.C.received the grant.
文摘This study aims to improve the performances of the high-pressure water descaling technology used in steel hot rolling processes.In particular,a 2050 mm hot rolling line is considered,and the problem is investigated by means of a fluid–structure interaction(FSI)method by which the descaling effect produced by rolling coils with different section sizes is examined.Assuming a flat fan-shaped nozzle at the entrance of the R1R2 roughing mill,the outflow field characteristics and the velocity distribution curve on the strike line(at a target distance of 30–120 mm)are determined.It is found that the velocity in the center region of the water jet with different target distances is higher than that in the boundary region.As the target distance increases,the velocity of the water jet in the central region decreases.Through comparison with experimental results,it is shown that the simulation model can accurately predict the impact position of the high-pressure water on the impact plate,thereby providing a computational scheme that can be used to optimize the nozzle space layout and improve the slabs’descent effect for different rolling specifications.
基金supported by National Natural Science Foundation of China (No.10975026)
文摘Interaction between high-intensity pulsed ion beam (HIPIB) and a double-layer target with titanium film on top of aluminum substrate was simulated. The two-dimensional nonlinear thermal conduction equations, with the deposited energy in the target taken as source term, were derived and solved by finite differential method. As a result, the two-dimensional spatial and temporal evolution profiles of temperature were obtained for a titanium/aluminum double-layer target irradiated by a pulse of HIPIB. The effects of ion beam current density on the phase state of the target materials near the film and substrate interface were analyzed. Both titanium and aluminum were melted near the interface after a shot when the ion beam current density fell in the range of 100 A/cm2 to 200 A/cm2.
基金Supported by a grant from the National High-Tech Research and Development Program (863 Program) of China (No: 2002AA214061).
文摘Objective: To evaluate the effect of magnetic nanoparticle containing 5-fluorouracil (5-FU) targeting in treating chol- angiocarcinoma based on internal magnetic fields built inside the tumor. Methods: 32 nude mice of BABL/C bearing ectopic tumor were built by subcutaneouly injecting cholangiocarcinoma cell line QBC 939. Three weeks after tumor inoculation, the animal models were divided equally into four groups at random including: (a) group A, consisting of internal magnetic field built by magnetic biliary stent wires inserted into tumor tissue and receiving magnetic nanoparticles containing 5-FU administered via tail vein injection at 250 mg/kg for consecutive five days; (b) group B, receiving placebo (sodium chloride); (c) group C, receiving pure magnetic biliary stent wires without the applying of magnetic nanoparticles; (d) group D, consisting of external magnetic fields and the same treatment of magnetic nanoparticles containing 5-FU as group A. The tumor volumes were measured every 3 days, totally six times from treatment started. Tumor tissues were observed by transmission electron microscope when the nude mice were killed after the observation period. Results: The experimental group (group A) showed significantly therapeutic efficacy. Moreover, apoptosis of tumor cells could be easily detected in this group. Conclusion: Magnetic particles containing 5-FU combined with internal magnetic field can effectively treat cholangiocarcinoma, and its therapeutic efficacy is better than that of the traditional method based on external magnetic fields.
基金supported by the National Basic Research Program of China(Grant No.2013CBA01501)the National Nature Science Foundation of China(Grant Nos.11135012,11520101003 and 11375262)the National High Technology Research and Development Program of China.
文摘Recently generation of strong magnetic(B)fields has been demonstrated in capacitor coils heated by high power laser pulses[S.Fujioka et al.,Sci.Rep.3,1170(2013)].This paper will present a direct measurement of B field generated with an open-ended coil target driven by a nanosecond laser pulse using ultrafast proton radiography.The radiographs are analyzed with particle-tracing simulations.The B field at the coil center is inferred to be ~50 T at an irradiance of ~5×10^(14) W·cm^(-2).The B field generation is attributed to the background cold electron flow pointing to the laser focal spot,where a target potential is induced due to the escape of energetic electrons.
基金Project supported by the National Natural Science Foundation of China(Nos.11772046 and 81870345)。
文摘Nanoparticle-mediated drug delivery is recognized as a promising option for targeted treatment of atherosclerosis. In this paper, the Eulerian-Lagrangian technique is adopted to simulate the delivery of drug-loaded nanoparticles to patient-specific atherosclerotic plaque with the aid of an external magnetic field. Plaques and vascular walls are introduced as porous media formulated by the Darcy-Forchheimer model in this targeted transport process. The results demonstrate that the delivery efficiency of particles to atherosclerosis depends on the external magnetic field, such as configuration and intensity, in which the configuration angle of the current wire is a key factor and the double current wires have advantages over the single current wire. Meanwhile, the delivery efficiency gradually decreases as the distance between the plaque cap and the current wire increases. Further, although augmenting the current or magnetic susceptibility can generally improve the delivery efficiency of nanoparticles, this increase is not apparent when small-sized nanoparticles are employed as drug transport particles. The results obtained can potentially serve as the guideline to optimize regimens for the targeted therapy of atherosclerosis.
文摘A novel robot navigation algorithm with global path generation capability is presented. Local minimum is a most intractable but is an encountered frequently problem in potential field based robot navigation.Through appointing appropriately some virtual local targets on the journey, it can be solved effectively. The key concept employed in this algorithm are the rules that govern when and how to appoint these virtual local targets. When the robot finds itself in danger of local minimum, a virtual local target is appointed to replace the global goal temporarily according to the rules. After the virtual target is reached, the robot continues on its journey by heading towards the global goal. The algorithm prevents the robot from running into local minima anymore. Simulation results showed that it is very effective in complex obstacle environments.
文摘In the initial phase of the physics experiment, the double-null divertor plates used consist of graphite armor tiles, Mo-alloy intermediate layers and Cu-alloy coolant tubes. In the later operating phase, tungsten will be used as armor tiles. A multi-physical field numerical analysis method is used in this paper. Its analysis model reflects more realistically the real divertor structure than other models. Two-dimensional (2D) and three-dimensional (3D) fluid flow field, temperature distribution and thermal stress analyses of the divertor plates are carried out by the ANSYS code. During the physics experimental phase with a heat flux of 1 MW/m2, a coolant velocity of 5.48 m/s, and a thermal stress of 750 kg/cm2, the graphite armor tiles successfully meet the requirements of temperature, thermal stress and sputtering erosion. The tungsten armor will be considered as a second candidate. The result of simulation can be used for upgrading the design parameters of the HL-2A poloidal divertor.
基金jointly sponsored by the National Nature Scientific Foundation of China(Grant.Nos.41930971 and 41775061)the National Key Research and Development Program of China(Grant No.2018YFC1506402)。
文摘Valuable dropsonde data were obtained from multiple field campaigns targeting tropical cyclones,namely Higos,Nangka,Saudel,and Atsani,over the western North Pacific by the Hong Kong Observatory and Taiwan Central Weather Bureau in 2020.The conditional nonlinear optimal perturbation(CNOP)method has been utilized in real-time to identify the sensitive regions for targeting observations adhering to the procedure of real-time field campaigns for the first time.The observing system experiments were conducted to evaluate the effect of dropsonde data and CNOP sensitivity on TC forecasts in terms of track and intensity,using the Weather Research and Forecasting model.It is shown that the impact of assimilating all dropsonde data on both track and intensity forecasts is case-dependent.However,assimilation using only the dropsonde data inside the sensitive regions displays unanimously positive effects on both the track and intensity forecast,either of which obtains comparable benefits to or greatly reduces deterioration of the skill when assimilating all dropsonde data.Therefore,these results encourage us to further carry out targeting observations for the forecast of tropical cyclones according to CNOP sensitivity.
文摘A novel modified four path method (FPM) is presented for calculating coupling field of super-low altitude aircraft target. Based on the hybrid method PO + MEC (Physical Optics and Method of Equivalent Currents), the antenna radiation pattern is introduced to consider the multipath interference from side lobe of seeker. The modified FPM is used to calculate the coupling field from super-low altitude aircraft target above different terrestrial environments. The curves of scattering coefficient are analyzed. The influences of height of target, root mean square (RMS), and incident angle on coupling field characteristics are discussed. The simulation results can be used for reference in detection for super-low altitude target and optimization for radar system.
基金the National Natural Science Foundation of China(No.6210011631)in part by the China Postdoctoral Science Foundation(No.2021M692628)。
文摘The automatic identification of underwater noncooperative targets without label records remains an arduous task considering the marine noise interference and the shortage of labeled samples.In particular,the data-driven mechanism of deep learning cannot identify false samples,aggravating the difficulty in noncooperative underwater target recognition.A semi-supervised ensemble framework based on vertical line array fusion and the sparse adversarial co-training algorithm is proposed to identify noncooperative targets effectively.The sound field cross-correlation compression(SCC)feature is developed to reduce noise and computational redundancy.Starting from an incomplete dataset,a joint adversarial autoencoder is constructed to extract the sparse features with source depth sensitivity,aiming to discover the unknown underwater targets.The adversarial prediction label is converted to initialize the joint co-forest,whose evaluation function is optimized by introducing adaptive confidence.The experiments prove the strong denoising performance,low mean square error,and high separability of SCC features.Compared with several state-of-the-art approaches,the numerical results illustrate the superiorities of the proposed method due to feature compression,secondary recognition,and decision fusion.
基金Sponsored by the Fundamental Research Funds for the Central Universities(Grant No.HIT.NSRIF.2014019)
文摘For high precision calibration of camera with large field-of-view,massive calibration points will be needed if traditional methods are selected,which makes the calibration complex and time-consuming.In order to solve this problem,a calibration method based on flexible planar target is proposed.In this method,distortion factor is firstly acquired by the invariance of cross ratio,and existing feature points are adjusted with the distortion factor.Then,a large number of points that will be used for the calibration are constructed with the adjusted feature points.Simultaneously,Tsai method is modified so as to reduce the complexity of calibration,which makes the process linear.The simulation and real experiments show that the method proposed in this paper is simple,linear,accurate and robust,and the precision of this method is close to that of Tsai method using abundant points.The method can satisfy the requirement of high precision calibration for camera with large field-of-view.
文摘针对无人机复杂环境下的全局航迹规划问题,将人工势场法与双向RRTs(Rapidly-exploring random trees)算法结合,提出一种改进双向RRTs算法。首先,目标偏置策略引导采样点以一定概率顺着目标点生成,同时随机树新节点受到障碍物斥力和目标点引力的合力影响有效避开障碍物生长,提高航迹搜寻效率,其次对随机树的节点扩展考虑了无人机飞行性能约束条件,最后采用3阶贝塞尔函数进一步航迹优化。仿真结果表明:二维和三维复杂环境中改进双向RRTs算法相比传统RRT、双向RRTs算法航迹搜索耗时减少了71.3%、24.7%和41.0%、18.6%,验证了改进算法全局搜索能力的快速性和有效性,能很好的应用于无人机离线全局航迹规划场合。