目的:研究结肠息肉的中医证型分布,同时探讨其中医证型与病理类型及发病因素的相关性,旨在为结肠息肉临床辨证和中医防治提供依据。方法:通过回顾性研究的方法获取并整理结肠息肉患者的基本信息、中医证型、病理分型、血脂程度及结肠镜...目的:研究结肠息肉的中医证型分布,同时探讨其中医证型与病理类型及发病因素的相关性,旨在为结肠息肉临床辨证和中医防治提供依据。方法:通过回顾性研究的方法获取并整理结肠息肉患者的基本信息、中医证型、病理分型、血脂程度及结肠镜结果等信息,包括性别、年龄、饮食习惯、吸烟饮酒量、三酰甘油(Triglycerides,TG)、总胆固醇(Total Cholesterol,TC)、高密度脂蛋白(High-density Lipoprotein,HDL)、低密度脂蛋白(Low Density Lipoprotein,LDL)、息肉病理类型。统计分析结肠息肉中医证型与病理类型及发病因素之间的相关性。结果:①中医证型分布规律:大肠湿热证199例(39.5%)>肝郁气滞证127例(25.2%)>脾胃虚弱证101例(20.0%)>瘀血内停证46例(9.1%)>寒湿内阻证30例(5.9%)。②结肠息肉患者年龄大多≥45岁,447例,占88.86%;饮食习惯以肥甘厚味为主,有208例,占41.35%;吸烟者232例,占46.13%;饮酒者136例,占27.04%。③结肠息肉患者中腺瘤性息肉患者295例,占58.65%,非腺瘤性息肉患者208例,占41.35%。④非高总胆固醇血症124例,占24.65%,高总胆固醇血症379例,占75.35%;非高甘油三酯血症136例,占27.03%,高甘油三酯血症367例,占72.97%;非高脂血症139例,占27.63%,高脂血症364例,占72.37%;非低高密度脂蛋白血症222例,占44.13%,低高密度脂蛋白血症281例,占55.87%。结论:结肠息肉中医证型以大肠湿热证多见。腺瘤性息肉中医证型以大肠湿热证为主,非腺瘤性息肉中炎性息肉以大肠湿热证为主,增生性息肉以肝郁气滞证多见,差异具有统计学意义(P<0.05)。不同证型高总胆固醇血症分布具有差异(P<0.05),以大肠湿热证多见;不同证型高总胆固醇血症、高脂血症、低高密度脂蛋白血症分布无差异(P>0.05)。展开更多
BACKGROUND： With mechanical ventilation widely used in intensive care unit, the ventilator associated pneumonia （VAP） has become a common and serious complication in critically ill patients. Compared with adults, t...BACKGROUND： With mechanical ventilation widely used in intensive care unit, the ventilator associated pneumonia （VAP） has become a common and serious complication in critically ill patients. Compared with adults, the incidence of VAP and the mortality are higher in children in pediatric intensive care unit （PICU） because of immune deficiency, severe basic diseases, and increased use of artificial airway or mechanical ventilation. Hence it is of significance to study the epidemiology and changes of antibacterial susceptibility in order to reduce the incidence and mortality of VAP in children.METHODS： From January 2008 to June 2010, 2758 children were treated in PICU of Wuhan Children＇s Hospital. Among them, 171 received mechanical ventilation over 48 hours in PICU, and 46 developed VAP. The distribution and drug-resistance pattern of the pathogenic bacteria isolated from lower respiratory tract aspirations were analyzed. RESULTS：A total of 119 pathogenic microbial strains were isolated. Gram-negative bacilli （G-） were the most （65.55%）, followed by fungi （21.01%） and gram-positive cocci （G~, 13.45%）. Among them, the most common pathogens were Acinetobacter baummannii, Escherichia coli, Klebsiella pneumoniae, candida albicans and coagulase-negative staphylococci. Antibiotic susceptibility tests indicated that the multiple drug-resistances of G- and G＋to antibiotics were serious. Most of G- was sensitive to ciprofloxacin, amikacin, imipenem, meropenem, cefoperazone-sulbactam and piperacillin-tazobactam. The susceptibility of G＋ to vancomycin, teicoplanin and linezolid were 100%. Fungi were almost sensitive to all the antifungal agents. The primary pathogens of VAP were G-, and their multiple drug-resistances were serious. CONCLUSION： In clinical practice we should choose the most sensitive drug for VAP according to pathogenic test.展开更多
文摘目的:研究结肠息肉的中医证型分布,同时探讨其中医证型与病理类型及发病因素的相关性,旨在为结肠息肉临床辨证和中医防治提供依据。方法:通过回顾性研究的方法获取并整理结肠息肉患者的基本信息、中医证型、病理分型、血脂程度及结肠镜结果等信息,包括性别、年龄、饮食习惯、吸烟饮酒量、三酰甘油(Triglycerides,TG)、总胆固醇(Total Cholesterol,TC)、高密度脂蛋白(High-density Lipoprotein,HDL)、低密度脂蛋白(Low Density Lipoprotein,LDL)、息肉病理类型。统计分析结肠息肉中医证型与病理类型及发病因素之间的相关性。结果:①中医证型分布规律:大肠湿热证199例(39.5%)>肝郁气滞证127例(25.2%)>脾胃虚弱证101例(20.0%)>瘀血内停证46例(9.1%)>寒湿内阻证30例(5.9%)。②结肠息肉患者年龄大多≥45岁,447例,占88.86%;饮食习惯以肥甘厚味为主,有208例,占41.35%;吸烟者232例,占46.13%;饮酒者136例,占27.04%。③结肠息肉患者中腺瘤性息肉患者295例,占58.65%,非腺瘤性息肉患者208例,占41.35%。④非高总胆固醇血症124例,占24.65%,高总胆固醇血症379例,占75.35%;非高甘油三酯血症136例,占27.03%,高甘油三酯血症367例,占72.97%;非高脂血症139例,占27.63%,高脂血症364例,占72.37%;非低高密度脂蛋白血症222例,占44.13%,低高密度脂蛋白血症281例,占55.87%。结论:结肠息肉中医证型以大肠湿热证多见。腺瘤性息肉中医证型以大肠湿热证为主,非腺瘤性息肉中炎性息肉以大肠湿热证为主,增生性息肉以肝郁气滞证多见,差异具有统计学意义(P<0.05)。不同证型高总胆固醇血症分布具有差异(P<0.05),以大肠湿热证多见;不同证型高总胆固醇血症、高脂血症、低高密度脂蛋白血症分布无差异(P>0.05)。
文摘BACKGROUND： With mechanical ventilation widely used in intensive care unit, the ventilator associated pneumonia （VAP） has become a common and serious complication in critically ill patients. Compared with adults, the incidence of VAP and the mortality are higher in children in pediatric intensive care unit （PICU） because of immune deficiency, severe basic diseases, and increased use of artificial airway or mechanical ventilation. Hence it is of significance to study the epidemiology and changes of antibacterial susceptibility in order to reduce the incidence and mortality of VAP in children.METHODS： From January 2008 to June 2010, 2758 children were treated in PICU of Wuhan Children＇s Hospital. Among them, 171 received mechanical ventilation over 48 hours in PICU, and 46 developed VAP. The distribution and drug-resistance pattern of the pathogenic bacteria isolated from lower respiratory tract aspirations were analyzed. RESULTS：A total of 119 pathogenic microbial strains were isolated. Gram-negative bacilli （G-） were the most （65.55%）, followed by fungi （21.01%） and gram-positive cocci （G~, 13.45%）. Among them, the most common pathogens were Acinetobacter baummannii, Escherichia coli, Klebsiella pneumoniae, candida albicans and coagulase-negative staphylococci. Antibiotic susceptibility tests indicated that the multiple drug-resistances of G- and G＋to antibiotics were serious. Most of G- was sensitive to ciprofloxacin, amikacin, imipenem, meropenem, cefoperazone-sulbactam and piperacillin-tazobactam. The susceptibility of G＋ to vancomycin, teicoplanin and linezolid were 100%. Fungi were almost sensitive to all the antifungal agents. The primary pathogens of VAP were G-, and their multiple drug-resistances were serious. CONCLUSION： In clinical practice we should choose the most sensitive drug for VAP according to pathogenic test.
