A total of 40 Wistar rats, weighing 130-140 g, were allocated randomly into four groups. They were orally administrated with 0 （control group, GC）, 64.18 （low-dose group, GL）, 128.36 （middle-dose group, GM）, and...A total of 40 Wistar rats, weighing 130-140 g, were allocated randomly into four groups. They were orally administrated with 0 （control group, GC）, 64.18 （low-dose group, GL）, 128.36 （middle-dose group, GM）, and 256.72 （high-dose group, GH） mg aluminum chloride （AlCl3） per kilogram body weight in drinking water for 120 days. Kidney coefficient and aluminum （Al） concentrations in blood and kidney were determined, and renal autopsy and histological changes were observed. The results showed that kidney coefficient in all Al-treated groups were obviously lower than that in GC （P〈0.01） and there was a dose-effect relationship. The kidneys were solid, lusterless and pale brown with white necrosis point on surface. Under electron microscope, renal cortex became thin, the renal tubule was narrowed and the epithelium dissolved; the renal glomerulus became atrophied and the glomerular became vasodilator. The Al concentrations in blood and kidney were higher in all Al-treated rats than those in GC （P〈0.01）, and there was a dose-effect relationship. The results indicated that sub-chronic Al exposure could lead to Al accumulation in kidney, restrain the development of kidney and cause the pathologic damage in rats.展开更多
Struthio linxiaensis is the oldest fossil ostrich from Asia till today. This paper analyzes the microstructure of the eggshell of Struthio linxiaensis. The SEM and light microscopic results show that a pathological st...Struthio linxiaensis is the oldest fossil ostrich from Asia till today. This paper analyzes the microstructure of the eggshell of Struthio linxiaensis. The SEM and light microscopic results show that a pathological structure occurred associated with the formation of pore canal. The feature of this structure is that crystals of the columnar layer are around the lower part of the pore canal, and formed a broad structure. This structure unit contracts upwards more severely than the canal and looks like a ＂garlic＂, which was observed in aumiotes eggshells for the first time. Many evidences indicate that this structure was deposited with the columns simultaneously. The radial section view suggests that the ＂garlic structure＂ is not a result of antiperistaltic waves in the avian oviduct. The most possible process of the ＂garlic structure＂ formation is the column units around the pore canals with imperfect acidifying when calcified, or have some correlations with the changes in the protein profiles of the organic matrix in the calcareous eggshell.展开更多
基金Supported by the Postgraduate Innovative Scientific Research Foundation Program of Helongjiang Province (YJSCX2012-026HLJ)
文摘A total of 40 Wistar rats, weighing 130-140 g, were allocated randomly into four groups. They were orally administrated with 0 （control group, GC）, 64.18 （low-dose group, GL）, 128.36 （middle-dose group, GM）, and 256.72 （high-dose group, GH） mg aluminum chloride （AlCl3） per kilogram body weight in drinking water for 120 days. Kidney coefficient and aluminum （Al） concentrations in blood and kidney were determined, and renal autopsy and histological changes were observed. The results showed that kidney coefficient in all Al-treated groups were obviously lower than that in GC （P〈0.01） and there was a dose-effect relationship. The kidneys were solid, lusterless and pale brown with white necrosis point on surface. Under electron microscope, renal cortex became thin, the renal tubule was narrowed and the epithelium dissolved; the renal glomerulus became atrophied and the glomerular became vasodilator. The Al concentrations in blood and kidney were higher in all Al-treated rats than those in GC （P〈0.01）, and there was a dose-effect relationship. The results indicated that sub-chronic Al exposure could lead to Al accumulation in kidney, restrain the development of kidney and cause the pathologic damage in rats.
文摘Struthio linxiaensis is the oldest fossil ostrich from Asia till today. This paper analyzes the microstructure of the eggshell of Struthio linxiaensis. The SEM and light microscopic results show that a pathological structure occurred associated with the formation of pore canal. The feature of this structure is that crystals of the columnar layer are around the lower part of the pore canal, and formed a broad structure. This structure unit contracts upwards more severely than the canal and looks like a ＂garlic＂, which was observed in aumiotes eggshells for the first time. Many evidences indicate that this structure was deposited with the columns simultaneously. The radial section view suggests that the ＂garlic structure＂ is not a result of antiperistaltic waves in the avian oviduct. The most possible process of the ＂garlic structure＂ formation is the column units around the pore canals with imperfect acidifying when calcified, or have some correlations with the changes in the protein profiles of the organic matrix in the calcareous eggshell.
