Purposes: To observe the characteristics of local electroretinogram (LERG) in normal subjects and patients with maculopathies, and to evaluate the applied worth of LERG and pattern visual evoked potential (PVEP) in ma...Purposes: To observe the characteristics of local electroretinogram (LERG) in normal subjects and patients with maculopathies, and to evaluate the applied worth of LERG and pattern visual evoked potential (PVEP) in maculopathies. Methods: LERGs at 5° and 15° macular regions were recorded from 27 normal subjects (54 eyes). The factors of age, different eyes and stimulate areas for LERG influence were observed. Meanwhile, the LERG and PVEP were recorded from 25 patients (35 eyes) with maculopathies for making contrast study. Results: In normal subjects, there was no significant influence of age to LERG. As the stimulated areas increased, the a- and b-wave amplitudes of LERG increased. In the patients with maculopathies, the a- and b-wave amplitudes of LERG at 5°, 10°and 15° macular regions were significantly lowered and the mean values of P1 latency were prolonged and N1-P1 amplitudes of VEP were lowered, comparing with the control group. In the nearing stimulated area (5°LERG and 14. 9×19°PVEP.),展开更多
Purpose:To study pattern reversal visual evoked potential(PVEPs)and deter-mine the developmental character and mature time of visual function in normal in-fants t different months of age.Methods:PVEPs were recorded fr...Purpose:To study pattern reversal visual evoked potential(PVEPs)and deter-mine the developmental character and mature time of visual function in normal in-fants t different months of age.Methods:PVEPs were recorded from115normal infants at3,6,9,12moths age.P1latency for different checks(1°40′，25′，6′）was analyzed and compared to those of normal adults,Changes of N1,N2latency of PVEPs were also exam-ioned.Results:P1 latency for all checks(1°40′,25′，6′）was significantly longer at 3months than at 6months of age(P<0.05),but no significant differences can be seen after 6months of age for largen(1°40′）and intermediate(25′）checks(P>0.05).P1latency for larger checks(1°40′）reached adult level after 3months of age,but not for the intermediate check(25′）,while P1latency for small check(6′）presented the character of fluctuation.Conclusion:The visual system continued to develop after birth and appeared a certain regularity,Our results showed thatP1latency for larger check(1°40′）reached adult levels after 3months of age.ButP1latency for intermediate check still has not reached adult levels after 3months of age.To deterine the age at which adult levels are finally reached,infants of 12months and older must be tested.The reason why P1latency for smaller check(6′）presented the character of fluctuation should be the temporal tuning function developing much more slowly.Eye Science1995;11:161-164.展开更多
Visual functions and nutrition metabolic characteristics werestudied in 8 subjects(16 eyes)with tobacco-toxic optic neuropathy(TTON).Their visual functions tested by psychophysical and electrophysiologicmethods showed...Visual functions and nutrition metabolic characteristics werestudied in 8 subjects(16 eyes)with tobacco-toxic optic neuropathy(TTON).Their visual functions tested by psychophysical and electrophysiologicmethods showed that:1.central vision diminished in 16 eyes,2.dyschromatopsias were found in 14 tested eyes,3.bilateral symmetricalcentral or cecocentral scotomas were the visual field characteristics in allcases,4.PVEP were severe abnormal in 3 spatial frequencies in all cases and56.3% of 15' checkboard ...展开更多
A novel method based on the extended infomax approach of independent component analysis (ICA) is proposed for the single trial estimation of multi channel pattern reversal visual evoked potential (PVEP). The clin...A novel method based on the extended infomax approach of independent component analysis (ICA) is proposed for the single trial estimation of multi channel pattern reversal visual evoked potential (PVEP). The clinical applications illustrate the encouraging performance of the method. The number of trials needed is reduced to 3, but the estimated VEP complex is clearer than that obtained by conventional ensemble averaging with 50 trials. By analyzing the time course and spatial pattern of the independent components (ICs) of the multi channel PVEP, one component is found to be reasonably related to the P100 peak.展开更多
文摘Purposes: To observe the characteristics of local electroretinogram (LERG) in normal subjects and patients with maculopathies, and to evaluate the applied worth of LERG and pattern visual evoked potential (PVEP) in maculopathies. Methods: LERGs at 5° and 15° macular regions were recorded from 27 normal subjects (54 eyes). The factors of age, different eyes and stimulate areas for LERG influence were observed. Meanwhile, the LERG and PVEP were recorded from 25 patients (35 eyes) with maculopathies for making contrast study. Results: In normal subjects, there was no significant influence of age to LERG. As the stimulated areas increased, the a- and b-wave amplitudes of LERG increased. In the patients with maculopathies, the a- and b-wave amplitudes of LERG at 5°, 10°and 15° macular regions were significantly lowered and the mean values of P1 latency were prolonged and N1-P1 amplitudes of VEP were lowered, comparing with the control group. In the nearing stimulated area (5°LERG and 14. 9×19°PVEP.),
文摘Purpose:To study pattern reversal visual evoked potential(PVEPs)and deter-mine the developmental character and mature time of visual function in normal in-fants t different months of age.Methods:PVEPs were recorded from115normal infants at3,6,9,12moths age.P1latency for different checks(1°40′，25′，6′）was analyzed and compared to those of normal adults,Changes of N1,N2latency of PVEPs were also exam-ioned.Results:P1 latency for all checks(1°40′,25′，6′）was significantly longer at 3months than at 6months of age(P<0.05),but no significant differences can be seen after 6months of age for largen(1°40′）and intermediate(25′）checks(P>0.05).P1latency for larger checks(1°40′）reached adult level after 3months of age,but not for the intermediate check(25′）,while P1latency for small check(6′）presented the character of fluctuation.Conclusion:The visual system continued to develop after birth and appeared a certain regularity,Our results showed thatP1latency for larger check(1°40′）reached adult levels after 3months of age.ButP1latency for intermediate check still has not reached adult levels after 3months of age.To deterine the age at which adult levels are finally reached,infants of 12months and older must be tested.The reason why P1latency for smaller check(6′）presented the character of fluctuation should be the temporal tuning function developing much more slowly.Eye Science1995;11:161-164.
基金This study was supported by Zhongshan ophthalmic Center,SUMS.
文摘Visual functions and nutrition metabolic characteristics werestudied in 8 subjects(16 eyes)with tobacco-toxic optic neuropathy(TTON).Their visual functions tested by psychophysical and electrophysiologicmethods showed that:1.central vision diminished in 16 eyes,2.dyschromatopsias were found in 14 tested eyes,3.bilateral symmetricalcentral or cecocentral scotomas were the visual field characteristics in allcases,4.PVEP were severe abnormal in 3 spatial frequencies in all cases and56.3% of 15' checkboard ...
基金Supported by the National Natural Science Foundation of China( No.5 993 7160 )
文摘A novel method based on the extended infomax approach of independent component analysis (ICA) is proposed for the single trial estimation of multi channel pattern reversal visual evoked potential (PVEP). The clinical applications illustrate the encouraging performance of the method. The number of trials needed is reduced to 3, but the estimated VEP complex is clearer than that obtained by conventional ensemble averaging with 50 trials. By analyzing the time course and spatial pattern of the independent components (ICs) of the multi channel PVEP, one component is found to be reasonably related to the P100 peak.
