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Modifed pennes' equation modelling bio-heat transfer in living tissues: analytical and numerical analysis 被引量:1
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作者 Ahmed Lakhssassi Emmanuel Kengne Hicham Semmaoui 《Natural Science》 2010年第12期1375-1385,共11页
Based on modified version of the Pennes' bio-heat transfer equation, a simplified one- dimensional bio-heat transfer model of the living tissues in the steady state has been applied on whole body heat transfer stu... Based on modified version of the Pennes' bio-heat transfer equation, a simplified one- dimensional bio-heat transfer model of the living tissues in the steady state has been applied on whole body heat transfer studies, and by using the Weierstrass' elliptic function, its corresponding analytic periodic and non-periodic solutions have been derived in this paper. Using the obtained analytic solutions, the effects of the thermal diffusivity, the temperature-inde- pendent perfusion component, and the temperature-dependent perfusion component in living tissues are analyzed numerically. The results show that the derived analytic solution is useful to easily and accurately study the thermal behavior of the biological system, and can be extended to applications such as parameter measurement, temperature field reconstruction and clinical treatment. 展开更多
关键词 bio-heat transfer equation pennes' Modified equation Weierstrass' FUNCTIONS JACOBI ELLIPTIC FUNCTIONS
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Investigation of nonlinear temperature distribution in biological tissues by using bioheat transfer equation of Pennes’ type 被引量:3
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作者 Ahmed Lakhssassi Emmanuel Kengne Hicham Semmaoui 《Natural Science》 2010年第3期131-138,共8页
In this paper, a two level finite difference scheme of Crank-Nicholson type is constructed and used to numerically investigate nonlinear temperature distribution in biological tissues described by bioheat transfer equ... In this paper, a two level finite difference scheme of Crank-Nicholson type is constructed and used to numerically investigate nonlinear temperature distribution in biological tissues described by bioheat transfer equation of Pennes’ type. For the equation under consideration, the thermal conductivity is either depth-dependent or tem-perature-dependent, while blood perfusion is temperature-dependent. In both cases of depth- dependent and temperature-dependent thermal conductivity, it is shown that blood perfusion decreases the temperature of the living tissue. Our numerical simulations show that neither the localization nor the magnitude of peak tempera-ture is affected by surface temperature;however, the width of peak temperature increases with surface temperature. 展开更多
关键词 Bioheat transfer equation of pennes TYPE pennes Bioheat transfer equation Modified Crank-Nicholson Method TWO-LEVEL FINITE DIFFERENCE Scheme
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Extended Generalized Riccati Equation Mapping for Thermal Traveling-Wave Distribution in Biological Tissues through a Bio-Heat Transfer Model with Linear/Quadratic Temperature-Dependent Blood Perfusion 被引量:1
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作者 Emmanuel Kengne Fathi Ben Hamouda Ahmed Lakhssassi 《Applied Mathematics》 2013年第10期1471-1484,共14页
Analytical thermal traveling-wave distribution in biological tissues through a bio-heat transfer (BHT) model with linear/quadratic temperature-dependent blood perfusion is discussed in this paper. Using the extended g... Analytical thermal traveling-wave distribution in biological tissues through a bio-heat transfer (BHT) model with linear/quadratic temperature-dependent blood perfusion is discussed in this paper. Using the extended generalized Riccati equation mapping method, we find analytical traveling wave solutions of the considered BHT equation. All the travelling wave solutions obtained have been used to explicitly investigate the effect of linear and quadratic coefficients of temperature dependence on temperature distribution in tissues. We found that the parameter of the nonlinear superposition formula for Riccati can be used to control the temperature of living tissues. Our results prove that the extended generalized Riccati equation mapping method is a powerful tool for investigating thermal traveling-wave distribution in biological tissues. 展开更多
关键词 bio-heat transfer pennes bio-heat Model TEMPERATURE-DEPENDENT Blood Perfusion Thermal Therapy EXTENDED GENERALIZED Riccati equation MAPPING Method
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A Mathematical Model to Solve Bio-Heat Transfer Problems through a Bio-Heat Transfer Equation with Quadratic Temperature-Dependent Blood Perfusion under a Constant Spatial Heating on Skin Surface 被引量:1
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作者 Emmanuel Kengne Idir Mellal +1 位作者 Mariem Ben Hamouda Ahmed Lakhssassi 《Journal of Biomedical Science and Engineering》 2014年第9期721-730,共10页
We consider the one-dimensional bio-heat transfer equation with quadratic temperature-dependent blood perfusion, which governs the temperature distribution inside biological tissues. Using an extended mapping method w... We consider the one-dimensional bio-heat transfer equation with quadratic temperature-dependent blood perfusion, which governs the temperature distribution inside biological tissues. Using an extended mapping method with symbolic computation, we obtain the exact analytical thermal traveling wave solution, which describes the non-uniform temperature distribution inside the bodies. The found exact solution is used to investigate the temperature distribution in the tissues. It is found that the surrounding medium with higher temperature does not necessarily imply that the tissue will quickly (after a short duration of heating process) reach the desired temperature. It is also found that increased perfusion causes a decline in local temperature. 展开更多
关键词 bio-heat transfer PROBLEMS pennes bio-heat Model TEMPERATURE-DEPENDENT Blood PERFUSION Thermal Therapy Extended Mapping Method
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基于混合生物热传导模型的Pennes方程的改进 被引量:2
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作者 马吉明 张向梅 +2 位作者 苏日建 赵进超 郭盛楠 《郑州轻工业学院学报(自然科学版)》 CAS 2015年第2期16-21,共6页
在血管树模拟研究的基础上,运用混合生物热传导模型并采用考虑血管和组织间局部传热的血液灌注率,改进了传统的Pennes生物传热方程.运用COMSOL Multiphysics对其进行仿真,并对改进前后Pennes方程求解结果进行比较,结果表明,改进后的Pen... 在血管树模拟研究的基础上,运用混合生物热传导模型并采用考虑血管和组织间局部传热的血液灌注率,改进了传统的Pennes生物传热方程.运用COMSOL Multiphysics对其进行仿真,并对改进前后Pennes方程求解结果进行比较,结果表明,改进后的Pennes方程能够显示出血管树对组织区域温度分布的局部影响,而传统Pennes方程则只表述了组织中温度分布的均匀形式. 展开更多
关键词 pennes 方程 血管树 混合生物热传导模型
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An Analytic Solution of One-dimensional Steady-state Pennes' Bioheat Transfer Equation in Cylindrical Coordinates 被引量:2
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作者 Kai Yue Xinxin Zhang Fan Yu 《Journal of Thermal Science》 SCIE EI CAS CSCD 2004年第3期255-258,共4页
Based on the Pennes’ bioheat transfer equation, a simplified one-dimensional bioheat transfer model of the cylindrical living tissues in the steady state has been set up for application in limb and whole body heat tr... Based on the Pennes’ bioheat transfer equation, a simplified one-dimensional bioheat transfer model of the cylindrical living tissues in the steady state has been set up for application in limb and whole body heat transfer studies, and by using the Bessel’s equation, its corresponding analytic solution has been derived in this paper. With the obtained analytic solution, the effects of the thermal conductivity, the blood perfusion, the metabolic heat generation, and the coefficient of heat transfer on the temperature distribution in living tissues are analyzed. The results show that the derived analytic solution is useful to easily and accurately study the thermal behavior of the biological system, and can be extended to such applications as parameter measurement, temperature field reconstruction and clinical treatment. 展开更多
关键词 bioheat transfer pennes equation ANALYTIC solution BESSEL functions.
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脉冲Er:YAG激光辐照多层牙齿组织换热特性分析
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作者 王栋 何昭炜 马俊青 《口腔生物医学》 2024年第4期217-222,244,共7页
目的:研究不同激光输入方式下,牙齿组织内部能量的沉积分布特征,搭建激光输入参数与牙齿组织内部温升的定性关系。方法:基于Pennes生物热传导方程,考虑牙齿组织的层状结构以及激光辐照时牙齿外表面与周围环境的热交换,构建Er:YAG激光辐... 目的:研究不同激光输入方式下,牙齿组织内部能量的沉积分布特征,搭建激光输入参数与牙齿组织内部温升的定性关系。方法:基于Pennes生物热传导方程,考虑牙齿组织的层状结构以及激光辐照时牙齿外表面与周围环境的热交换,构建Er:YAG激光辐照牙齿组织的热输运模型。借助有限差分法,对不同激光输入方式下牙齿组织内部温升的时-空分布特征进行了数值模拟和对比分析。结果:激光能量输入方式的改变(脉冲功率、脉宽、脉冲个数、脉冲间隔)对于牙齿组织的温升将产生显著的作用效果,并且其作用效果会随着深度的增加而逐渐衰减;输入总能量一定的前提下,输入方式的作用效果仅集中在照射表面附近,对于组织内部牙髓腔壁面的温升几乎不产生影响。此外,牙齿组织外表面与周围环境的热交换一定程度上抑制牙齿组织的温升并加速其冷却进程。结论:激光输入方式对牙齿组织的温升效果存在重要影响,在其与牙齿组织过程前后需考虑外表面与环境的热交换。 展开更多
关键词 ER:YAG激光 层状牙齿组织 光热效应 pennes生物热传导方程 表面热交换
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激光诱导间质热疗中生物组织的温度场研究 被引量:9
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作者 包美芳 钱志余 +3 位作者 李韪韬 肖笛 王晋阳 钱露 《光子学报》 EI CAS CSCD 北大核心 2011年第5期718-721,共4页
激光诱导间质热疗疗效评估的前提是必须获得准确的激光在不同功率、不同照射时间的生物组织温度场分布.利用多物理场直接耦合分析软件COMSOL Multiphysics构建了在组织光学参量不变情况下的三维有限元传热模型.该模型基于Pennes生物传... 激光诱导间质热疗疗效评估的前提是必须获得准确的激光在不同功率、不同照射时间的生物组织温度场分布.利用多物理场直接耦合分析软件COMSOL Multiphysics构建了在组织光学参量不变情况下的三维有限元传热模型.该模型基于Pennes生物传热方程和轴对称高斯形状的激光光束热源方程,参量针对离体猪肝组织,考虑到了生物组织热物性密度、比热和热导率随温度变化的情况.仿真获得激光功率为0.77 W、0.95 W、1.23 W,照射时间为10~90 s,径向距离0~2 mm范围和轴向距离0~4 mm范围的温度场数据集.利用拟合算法,获得了自变量为激光功率、照射时间、径向距离和轴向距离的生物组织温度场分布模型.将功率为0.88 W和1.05 W时的结果与Pennes方程结果相比较,两者误差在5%以内. 展开更多
关键词 激光诱导间质热疗 温度场 有限元 pennes生物传热方程
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高频ns脉冲串作用下肝脏肿瘤热效应的多参数有限元仿真 被引量:3
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作者 米彦 芮少琴 +4 位作者 李成祥 姚陈果 徐进 卞昌浩 唐雪峰 《高电压技术》 EI CAS CSCD 北大核心 2017年第8期2477-2485,共9页
为了综合传统不可逆电穿孔和ns脉冲的特点,充分发挥脉冲电场非热治疗肿瘤的优势,将高频ns脉冲串引入到消融肿瘤组织的应用中,并研究了此高频ns脉冲串在生物组织中产生的热效应。通过多参数有限元方法对施加1对针电极的肝脏和肿瘤组织的... 为了综合传统不可逆电穿孔和ns脉冲的特点,充分发挥脉冲电场非热治疗肿瘤的优势,将高频ns脉冲串引入到消融肿瘤组织的应用中,并研究了此高频ns脉冲串在生物组织中产生的热效应。通过多参数有限元方法对施加1对针电极的肝脏和肿瘤组织的温度以及热损伤进行了仿真,施加的电压范围为1~4 k V,脉冲宽度范围为50~500 ns,重复频率介于100 k Hz^1 MHz之间,脉冲串长度为100μs,脉冲串的重复频率为1 Hz。使用Pennes生物传热方程计算电热耦合下的温度,并根据Arrhenius公式计算热损伤。结果表明:肿瘤在单个脉冲串作用下在100μs时刻达到的最高温度为49.26℃;在1 s时刻最高温度为40.4℃,经过1 s时刻之后热损伤的累积程度只有0.001 6,不会造成热损伤;通过参数拟合,可以得到任意参数下的组织温度以及热损伤。研究结果可为将来的实验研究提供参数选择的理论依据。 展开更多
关键词 温度 热损伤 肿瘤 高频ns脉冲串 pennes生物传热方程 有限元
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激光辐照下皮肤组织中温度场的理论分析和数值模拟 被引量:6
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作者 沈桂平 谢树森 《福建师范大学学报(自然科学版)》 CAS CSCD 2002年第4期26-29,共4页
基于 Pennes传热方程 ,采用更能反映活体组织真实情况的血液灌注率和代谢热产率 ,从理论上分析了激光作用在生物皮肤组织时所引起的组织温度场变化 ,给出了皮肤组织温度变化的分析解 ,数值模拟了激光辐照下组织的温度场分布 .并讨论了... 基于 Pennes传热方程 ,采用更能反映活体组织真实情况的血液灌注率和代谢热产率 ,从理论上分析了激光作用在生物皮肤组织时所引起的组织温度场变化 ,给出了皮肤组织温度变化的分析解 ,数值模拟了激光辐照下组织的温度场分布 .并讨论了激光辐照时间、组织深度以及生物组织热物性对组织温升的影响 . 展开更多
关键词 数值模拟 激光福照 pennes传热方程 皮肤组织 温度场 激光生物医学
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亚低温治疗中颅脑径向温度的数值模拟 被引量:3
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作者 冯俊小 顾静 刘文杰 《华北电力大学学报(自然科学版)》 CAS 北大核心 2010年第1期78-82,共5页
近年来亚低温逐步应用于临床脑保护治疗。采用Pennes血液对流项处理方法,建立颅脑传热的一维球坐标模型,模拟正常状态下人脑温度分布和实施亚低温冷却治疗后的脑温变化。分析了模型中不同的物性参数对颅脑温度分布的影响,据此提出了有... 近年来亚低温逐步应用于临床脑保护治疗。采用Pennes血液对流项处理方法,建立颅脑传热的一维球坐标模型,模拟正常状态下人脑温度分布和实施亚低温冷却治疗后的脑温变化。分析了模型中不同的物性参数对颅脑温度分布的影响,据此提出了有效降低脑温的方法。 展开更多
关键词 亚低温 生物传热 pennes方程 颅脑模型 数值模拟
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亚低温治疗中颅脑温度场的三维数值模拟和实验研究 被引量:1
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作者 冯俊小 蒋彦军 顾静 《热科学与技术》 CAS CSCD 2007年第1期18-25,共8页
研究了亚低温治疗过程中颅脑温度场的变化规律及影响因素并提出降低颅脑温度的有效方法。基于Pennes生物传热方程,利用有限容积法建立颅脑传热的三维球坐标模型,数值方法求解亚低温治疗过程中颅脑内部的温度变化规律,通过活体动物试验... 研究了亚低温治疗过程中颅脑温度场的变化规律及影响因素并提出降低颅脑温度的有效方法。基于Pennes生物传热方程,利用有限容积法建立颅脑传热的三维球坐标模型,数值方法求解亚低温治疗过程中颅脑内部的温度变化规律,通过活体动物试验对该方法进行评价,并分析模型中主要参数:血液灌注率、新陈代谢率和动脉血液温度对颅脑温度分布的影响。通过数值计算,得到不同情况下颅脑的温度分布,给出降低脑温的有效方法。所建模型较真实反映了实际颅脑温度变化,数值模拟结果对亚低温治疗的深入探讨具有参考价值。 展开更多
关键词 亚低温 生物传热 pennes方程 数值模拟
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Effect of Metabolic Reactions on Thermoregulation in Human Males and Females Body 被引量:1
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作者 Saraswati Acharya D. B. Gurung V. P. Saxena 《Applied Mathematics》 2013年第5期39-48,共10页
The paper describes the study of metabolic effect relying on dermal thicknesses of males and females for temperature distribution of the layers of dermal part at various atmospheric temperatures. The study has been ca... The paper describes the study of metabolic effect relying on dermal thicknesses of males and females for temperature distribution of the layers of dermal part at various atmospheric temperatures. The study has been carried out for one dimensional steady and unsteady cases using finite element method. Lower percentage of muscle mass and higher percentage of adipose tissue in subcutaneous part of females result lower metabolic rate compared to males. Metabolism is considered as a heat source within the body tissue. The appropriate physical and physiological parameters together with suitable boundary conditions that affect the heat regulations have been incorporated in the model. 展开更多
关键词 Finite Element Method pennes bio-heat equation DERMAL Parts
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激光照射下生物组织内部温度分布的解析式
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作者 宋伟宏 熊国欣 +1 位作者 王天军 李立本 《山西师范大学学报(自然科学版)》 2010年第1期71-75,共5页
基于Pennes生物传热方程,建立血液灌注率随时间变化条件下,激光与生物活体组织热相互作用的理论模型,通过数学物理方程求解该模型得出一维瞬态温度时空分布的解析函数表达式,从而为激光在医学中的应用提供理论依据.
关键词 激光 生物组织 pennes生物传热方程 热传导方程的解析解
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穿着特高压屏蔽服后个体热舒适系统的数值仿真研究
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作者 方玉群 何强 +3 位作者 赵寿生 肖伟民 谢鹏 秦威南 《中国体视学与图像分析》 2018年第1期60-67,共8页
本文基于通用Pennes生物传热学理论方程,对穿着屏蔽服的背部单元传热过程进行数值计算,得出了背部单元在不同温度环境下的温度分布,并建立了附加强制对流换热风扇的个体背部传热几何模型,确定了风扇对个体进行散热的可能性。在此基础上... 本文基于通用Pennes生物传热学理论方程,对穿着屏蔽服的背部单元传热过程进行数值计算,得出了背部单元在不同温度环境下的温度分布,并建立了附加强制对流换热风扇的个体背部传热几何模型,确定了风扇对个体进行散热的可能性。在此基础上,建立了个体数值模型,利用热舒适度的概念,分析加入舒适系统后的屏蔽服内部环境的单体能量耗散环境,并且借用热舒适评价指标PMV(Predicted Mean Vote)、PPD(Predicted Percentage Dissatisfied),建立适用于单体热舒适标准的研究体系。 展开更多
关键词 热舒适 pennes方程 生物传热
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Modeling on Metabolic Rate and Thermoregulation in Three Layered Human Skin during Carpentering, Swimming and Marathon
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作者 Dev Chandra Shrestha Saraswati Acharya Dil Bahadur Gurung 《Applied Mathematics》 2020年第8期753-770,共18页
Metabolisms play a vital role in thermoregulation in the human body. The metabolic rate varies with the activity levels and has different behaviors in nature depending on the physical activities of the person. During ... Metabolisms play a vital role in thermoregulation in the human body. The metabolic rate varies with the activity levels and has different behaviors in nature depending on the physical activities of the person. During the activity, metabolic rate increases rapidly at the beginning and then increases slowly to become almost constant after a certain time. So, its behavior is as logistics in nature. The high metabolic rate during activity causes the increase of body core temperature up to 39&#730;C <a href="#ref1">[1]</a> <a href="#ref2">[2]</a>. The logistic model of metabolic rate is used to re-model Pennes’ bioheat equation for the study of temperature distribution in three layered human dermal parts during carpentering, swimming and marathon. The finite element method is used to obtain the solution of the model equation. The results demonstrate that there is a significant change in tissue temperature due to sweating and ambient temperature variations. 展开更多
关键词 pennes bio-heat equation Metabolic Rate Finite Element Method Physical Activities THERMOREGULATION
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一种新的血流建模方法及其在红外人脸识别中的应用
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作者 谢志华 《山东大学学报(工学版)》 CAS 北大核心 2013年第5期1-5,12,共6页
为了从时延红外人脸图像中提取出更加稳定的血流特征,提出1种新的基于生物热传模型的人脸血流图建模方法,并应用于人脸识别。基于生物热传模型中经典的Pennes生物传热方程通过离散化建模,得到对应的血流图。然后,基于红外人脸图像低分... 为了从时延红外人脸图像中提取出更加稳定的血流特征,提出1种新的基于生物热传模型的人脸血流图建模方法,并应用于人脸识别。基于生物热传模型中经典的Pennes生物传热方程通过离散化建模,得到对应的血流图。然后,基于红外人脸图像低分辨率的特点,对得到的血流图采用经典主成分分析PCA(principal component analysis,PCA)+Fisher线性鉴别分析(Fisher linear discriminant analysis,FLD)的方法进行人脸识别。实验结果表明:本研究提出的血流计算方法充分考虑到血流之间的关联性,可以得到更加稳定的血流特征,用于人脸识别,在不同环境温度的情况下(对于时延数据)具有较强的鲁棒性。 展开更多
关键词 生物热传学 pennes方程 血流图 人脸识别 鲁棒性
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Mathematical and numerical analysis of thermal distribution in cancerous tissues under the local heat therapy 被引量:1
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作者 M. A. Khanday Khalid Nazir 《International Journal of Biomathematics》 2017年第7期157-166,共10页
The main purpose of this study is to investigate the thermal behavior of living tissues in the presence of spatial external heat source. An effort has been made to formulate the mathematical model to study the tempera... The main purpose of this study is to investigate the thermal behavior of living tissues in the presence of spatial external heat source. An effort has been made to formulate the mathematical model to study the temperature distribution in in vivo tissues of the human body. The mathematical formulation is governed by bio-heat equation together with appropriate initial, boundary and interface conditions. The solution of the model was carried out using variational finite element method and computational simulations. The model describes the exchange of heat between the internal biological tissues and other surrounding media. The effect of external heat source under different conditions of atmospheric temperature and as a local hyperthermic method provides an impor- tant information to the temperature regulation in biological tissues under normal and malignant conditions. Thermal fluctuations at the targeted regions were obtained with respect to various time-dependent heating sources and scattering coefficients. The results obtained may be helpful for clinical purposes especially in the treatment of cancerous tumors through radiotherapy and other local hyperthermic approaches. 展开更多
关键词 Variational finite element method pennes bio-heat equation local hyper-thermia tumor cells.
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