Outcomes of small gauge pars plicata vitrectomy for patients with persistent fetal vasculature:a report of 105 cases

AIM：To evaluate the surgical outcomes in eyes with persistent fetal vasculatures（PFV） managed by small gauge pars plicata vitrectomy.METHODS：Consecutive patients with PFV treated by small gauge pars plicata vitrectomy at Beijing Tongren Eye Center between January 2010 and January 2013 were retrospectively reviewed.RESULTS：A total of 118 eyes of 105 patients with PFV were included and undergone small gauge pars plicata vitrectomy,of which 84（71.2%） eyes had lensectomy and 16（13.6%） eyes had lens aspiration and immediate intraocular lens implantation.The percentage of sutured scleral incision of 23 gauge vitrectomy（71.7%,33/46） was higher than that of the 25 gauge vitrectomy（18.1%,13/72）.At last follow-up,visual acuity remained stable in 34 eyes（28.8%） and improved in 84 eyes（71.2%）.Age at surgery（less than 2 y）,anterior type of PFV,and immediate IOL implantation were associated with postoperative improved visual acuity.Sixty five（55.1%） eyes had retinal detachment preoperatively,among which 33（50.8%,33/65） eyes had retinal reattachment or partial retinal reattachment.CONCLUSION：The results suggest that cases with PFV have a potential for developing good visual acuity after small gauge pars plicata vitrectomy with favorable anatomic outcomes and acceptable rate of serious surgical complications.

Ocular development in children with unilateral congenital cataract and persistent fetal vasculature

AIM: To investigate the ocular development of patients who had unilateral congenital cataract(CC) combined with persistent fetal vasculature(PFV).METHODS: This cross-sectional, observational study included patients who had unilateral CC and PFV and those with isolated unilateral CC.Axial length(AL), keratometry, anterior chamber depth(ACD), lens thickness, and vitreous length were obtained.The ocular biometric parameters of the affected eyes of patients with CC and PFV were compared with the fellow eyes and with the affected eyes of patients with isolated CC.RESULTS: A total of 110 patients were included and divided into 4 groups: group 1(18 patients with CC and PFV, <24 mo), group 2(22 patients with CC and PFV, ≥24 mo), group 3(35 patients with CC, <24 mo), and group 4(35 patients with CC, ≥24 mo).The ALs of the affected eyes were shorter than those of the fellow eyes in group 1(20.02±1.06 vs 20.66±0.63 mm, P=0.025).While the ALs of the affected eyes were longer than those of the fellow eyes in group 2(23.18±2.00 vs 22.31±1.06 mm, P=0.044) and group 4(22.64±1.80 vs 22.02±1.01 mm, P=0.033).The keratometries of the affected eyes were steeper than those of the fellow eyes in group 2(44.78±1.66 vs 43.83±1.38 D,P=0.041) and group 4(43.76±1.91 vs 43.34±1.46 D, P=0.043).No difference of ACDs between two eyes was found in all groups(all P>0.05).CONCLUSION: Compared with the fellow eyes, the ALs of the eyes with unilateral CC and PFV are shorter in patients younger than 24 mo and longer in those older than 24 mo;the keratometries of the eyes with unilateral CC and PFV are steeper in patients older than 24 mo and similar with those younger than 24 mo.These findings provide further understanding of ocular development in patients with both CC and PFV.