SOME soil, moss, kelp and reindeer liver were collected at 5 sites in a wide range of the Canadi an Arctic from 58°N to 81°31′N by the First Scientific Expedition of China to Canadian Arctic during April th...SOME soil, moss, kelp and reindeer liver were collected at 5 sites in a wide range of the Canadi an Arctic from 58°N to 81°31′N by the First Scientific Expedition of China to Canadian Arctic during April through May, 1995. The concentrations of persistent organochlorine HCH and DDT of these samples were determined. After sampling, the samples were extracted with appropriate solvents, analyzed by packed column gas chromatography with electron capture展开更多
Environmental pollution has become one of the greatest problems in the world, and the concerns about environmental pollutants released by human activities from agriculture and industrial production have been continuou...Environmental pollution has become one of the greatest problems in the world, and the concerns about environmental pollutants released by human activities from agriculture and industrial production have been continuously increasing. Although intense efforts have been made to understand the health effects of environmental pollutants, most studies have only focused on direct toxic effects and failed to simultaneously evaluate the long-term adaptive, compensatory and secondary impacts on health. Burgeoning evidence suggests that environmental pollutants may directly or indirectly give rise to disordered element homeostasis, such as for iron. It is crucially important to maintain concerted cellular and systemic iron metabolism. Otherwise, disordered iron metabolism would lead to cytotoxicity and increased risk for various diseases, including cancers. Thus, study on the effects of environmental pollutants upon iron homeostasis is urgently needed. In this review, we recapitulate the available findings on the direct or indirect impacts of environmental pollutants, including persistent organic pollutants（POPs）, heavy metals and pesticides, on iron homeostasis and associated adverse health problems. In view of the unanswered questions, more efforts are warranted to investigate the disruptive effects of environmental pollutants on iron homeostasis and consequent toxicities.展开更多
文摘SOME soil, moss, kelp and reindeer liver were collected at 5 sites in a wide range of the Canadi an Arctic from 58°N to 81°31′N by the First Scientific Expedition of China to Canadian Arctic during April through May, 1995. The concentrations of persistent organochlorine HCH and DDT of these samples were determined. After sampling, the samples were extracted with appropriate solvents, analyzed by packed column gas chromatography with electron capture
基金supported by a grant under the national " 973 " program (No: 2014CB932000)the Strategic Priority Research Program of the Chinese Academy of Sciences (No.XDB14000000)the National Natural Science Foundation of China (Nos: 21425731, 21377159, 21177151, and 21321004)
文摘Environmental pollution has become one of the greatest problems in the world, and the concerns about environmental pollutants released by human activities from agriculture and industrial production have been continuously increasing. Although intense efforts have been made to understand the health effects of environmental pollutants, most studies have only focused on direct toxic effects and failed to simultaneously evaluate the long-term adaptive, compensatory and secondary impacts on health. Burgeoning evidence suggests that environmental pollutants may directly or indirectly give rise to disordered element homeostasis, such as for iron. It is crucially important to maintain concerted cellular and systemic iron metabolism. Otherwise, disordered iron metabolism would lead to cytotoxicity and increased risk for various diseases, including cancers. Thus, study on the effects of environmental pollutants upon iron homeostasis is urgently needed. In this review, we recapitulate the available findings on the direct or indirect impacts of environmental pollutants, including persistent organic pollutants（POPs）, heavy metals and pesticides, on iron homeostasis and associated adverse health problems. In view of the unanswered questions, more efforts are warranted to investigate the disruptive effects of environmental pollutants on iron homeostasis and consequent toxicities.
