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A frequency servo SoC with output power stabilization loop technology for miniaturized atomic clocks 被引量:1
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作者 Hongyang Zhang Xinlin Geng +3 位作者 Zonglin Ye Kailei Wang Qian Xie Zheng Wang 《Journal of Semiconductors》 EI CAS CSCD 2024年第6期13-22,共10页
A frequency servo system-on-chip(FS-SoC)featuring output power stabilization technology is introduced in this study for high-precision and miniaturized cesium(Cs)atomic clocks.The proposed power stabilization loop(PSL... A frequency servo system-on-chip(FS-SoC)featuring output power stabilization technology is introduced in this study for high-precision and miniaturized cesium(Cs)atomic clocks.The proposed power stabilization loop(PSL)technique,incorporating an off-chip power detector(PD),ensures that the output power of the FS-SoC remains stable,mitigating the impact of power fluctuations on the atomic clock's stability.Additionally,a one-pulse-per-second(1PPS)is employed to syn-chronize the clock with GPS.Fabricated using 65 nm CMOS technology,the measured phase noise of the FS-SoC stands at-69.5 dBc/Hz@100 Hz offset and-83.9 dBc/Hz@1 kHz offset,accompanied by a power dissipation of 19.7 mW.The Cs atomic clock employing the proposed FS-SoC and PSL obtains an Allan deviation of 1.7×10^(-11) with 1-s averaging time. 展开更多
关键词 CMOS technology atomic clock phase-locked loop output power stabilization 1PPS
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Gigahertz frequency hopping in an optical phase-locked loop for Raman lasers
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作者 毛德凯 税鸿冕 +3 位作者 殷国玲 彭鹏 王春唯 周小计 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期60-65,共6页
Raman lasers are essential in atomic physics,and the development of portable devices has posed requirements for time-division multiplexing of Raman lasers.We demonstrate an innovative gigahertz frequency hopping appro... Raman lasers are essential in atomic physics,and the development of portable devices has posed requirements for time-division multiplexing of Raman lasers.We demonstrate an innovative gigahertz frequency hopping approach of a slave Raman laser within an optical phase-locked loop(OPLL),which finds practical application in an atomic gravimeter,where the OPLL frequently switches between near-resonance lasers and significantly detuned Raman lasers.The method merges the advantages of rapid and extensive frequency hopping with the OPLL’s inherent low phase noise,and exhibits a versatile range of applications in compact laser systems,promising advancements in portable instruments. 展开更多
关键词 Raman lasers optical phase-locked loop frequency hopping
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CMOS analog and mixed-signal phase-locked loops: An overview 被引量:3
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作者 Zhao Zhang 《Journal of Semiconductors》 EI CAS CSCD 2020年第11期13-30,共18页
CMOS analog and mixed-signal phase-locked loops(PLL)are widely used in varies of the system-on-chips(SoC)as the clock generator or frequency synthesizer.This paper presents an overview of the AMS-PLL,including:1)a bri... CMOS analog and mixed-signal phase-locked loops(PLL)are widely used in varies of the system-on-chips(SoC)as the clock generator or frequency synthesizer.This paper presents an overview of the AMS-PLL,including:1)a brief introduction of the basics of the charge-pump based PLL,which is the most widely used AMS-PLL architecture due to its simplicity and robustness;2)a summary of the design issues of the basic CPPLL architecture;3)a systematic introduction of the techniques for the performance enhancement of the CPPLL;4)a brief overview of ultra-low-jitter AMS-PLL architectures which can achieve lower jitter(<100 fs)with lower power consumption compared with the CPPLL,including the injection-locked PLL(ILPLL),subsampling(SSPLL)and sampling PLL(SPLL);5)a discussion about the consideration of the AMS-PLL architecture selection,which could help designers meet their performance requirements. 展开更多
关键词 phase-locked loop(PLL) charge-pump based PLL(CPPLL) ultra-low-jitter PLL injection-locked PLL(ILPLL) subsampling PLL(SSPLL) sampling PLL(SPLL)
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An improved arctangent algorithm based on phase-locked loop for heterodyne detection system 被引量:1
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作者 晏春回 王挺峰 +2 位作者 李远洋 吕韬 吴世松 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第3期141-148,共8页
We present an ameliorated arctangent algorithm based on phase-locked loop for digital Doppler signal processing,utilized within the heterodyne detection system. We define the error gain factor given by the approximati... We present an ameliorated arctangent algorithm based on phase-locked loop for digital Doppler signal processing,utilized within the heterodyne detection system. We define the error gain factor given by the approximation of Taylor expansion by means of a comparison of the measured values and true values. Exact expressions are derived for the amplitude error of two in-phase & quadrature signals and the frequency error of the acousto-optic modulator. Numerical simulation results and experimental results make it clear that the dynamic instability of the intermediate frequency signals leads to cumulative errors, which will spiral upward. An improved arctangent algorithm for the heterodyne detection is proposed to eliminate the cumulative errors and harmonic components. Depending on the narrow-band filter, our experiments were performed to realize the detectable displacement of 20 nm at a detection distance of 20 m. The aim of this paper is the demonstration of the optimized arctangent algorithm as a powerful approach to the demodulation algorithm, which will advance the signal-to-noise ratio and measurement accuracy of the heterodyne detection system. 展开更多
关键词 HETERODYNE detection LASER applications arctangent ALGORITHM phase-locked loop
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Design of radiation hard phase-locked loop at 2.5 GHz using SOS-CMOS 被引量:1
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作者 Partha Pratim Ghosh Jung Sungyong 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第6期1159-1166,共8页
A radiation hard phase-locked loop (PLL) is designed at 2.5 GHz using silicon on sapphire complementary metal-oxide-semiconductor process. Radiation hardness is achieved through improving circuit design without sacr... A radiation hard phase-locked loop (PLL) is designed at 2.5 GHz using silicon on sapphire complementary metal-oxide-semiconductor process. Radiation hardness is achieved through improving circuit design without sacrificing real estate. Stability is guaranteed by a fully self-bias architecture. The lock time of PLL is minimized by maximizing the loop bandwidth. Frequency tuning range of voltage controlled oscillator is significantly enhanced by a novel load configuration. In addition, multiple bias stages, asynchronous frequency divider, and silicon on sapphire process jointly make the proposed PLL more radiation hard. Layout of this PLL is simulated by Cadence Spectre RF under both single event effect and total induced dose effect. Simulation results demonstrate excellent stability, lock time 〈 600 ns, frequency tuning range [1.57 GHz, 3.46 GHz], and jitter 〈 12 ps. Through comparison with PLLs in literatures, the PLL is especially superior in terms of lock time and frequency tuning range performances. 展开更多
关键词 phase-locked loop radiation hard self-bias silicon on sapphire complementary metal-oxidesemiconductor.
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A 5.12-GHz LC-based phase-locked loop for silicon pixel readouts of high-energy physics 被引量:1
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作者 Xiao-Ting Li Wei Wei +3 位作者 Ying Zhang Xiong-Bo Yan Xiao-Shan Jiang Ping Yang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2022年第7期49-59,共11页
There is an urgent need for high-quality and high-frequency clock generators for high-energy physics experiments.The transmission data rate exceeds 10 Gbps for a single channel in future readout electronics of silicon... There is an urgent need for high-quality and high-frequency clock generators for high-energy physics experiments.The transmission data rate exceeds 10 Gbps for a single channel in future readout electronics of silicon pixel detectors.Others,such as time measurement detectors,require a high time resolution based on the time-to-digital readout architecture.A phase-locked loop(PLL)is an essential and broadly used circuit in these applications.This study presents an application-specific integrated circuit of a low-jitter,low-power LC-tank that is PLL fabricated using 55-nm CMOS technology.It includes a 3rd-order frequency synthesis loop with a programmable bandwidth,a divide-by-2 pre-scaler,standard low-voltage differential signaling interfaces,and a current mode logic(CML)driver for clock transmissions.All the d-flip-flop dividers and phase-frequency detectors are protected from single-event upsets using the triple modular redundancy technique.The proposed VCO uses low-pass filters to suppress the noise from bias circuits.The tested LC-PLL covers a frequency locking range between 4.74 GHz and 5.92 GHz with two sub-bands.The jitter measurements of the frequency-halved clock(2.56 GHz)are less than 460 fs and 0.8 ps for the random and deterministic jitters,respectively,and a total of 7.5 ps peak-to-peak with a bit error rate of 10^(-12).The random and total jitter values for frequencies of 426 MHz and 20 MHz are less than 1.8 ps and 65 ps,respectively.The LC-PLL consumed 27 mW for the core and 73.8 mW in total.The measured results nearly coincided with the simulations and validated the analyses and tests. 展开更多
关键词 LC phase-locked loop Analog electronic circuits Front-end electronics for detector readout High-energy physics experiments
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A LOW POWER TIME-TO-DIGITAL CONVERTER FOR ALL-DIGITAL PHASE-LOCKED LOOP 被引量:1
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作者 Yu Guangming Wang Yu Yang Huazhong 《Journal of Electronics(China)》 2011年第3期402-408,共7页
Time-to-Digital Converter (TDC) is a key block used as the phase/frequency detector in an All-Digital Phase-Locked Loop (ADPLL). Usually, it occupies a large proportion of ADPLL's total power consumption up to abo... Time-to-Digital Converter (TDC) is a key block used as the phase/frequency detector in an All-Digital Phase-Locked Loop (ADPLL). Usually, it occupies a large proportion of ADPLL's total power consumption up to about 30% to 40%. In this paper, the detailed power consumption of different components in the TDC is analyzed. A Power Management Block (PMB) is presented for the TDC to reduce its power consumption. A 24-bits TDC core with the proposed PMB is implemented in HJTC 0.18 μm CMOS technology. Simulation results show that up to 84% power reduction is achieved using our proposed technique. 展开更多
关键词 Low power Power management All-Digital phase-locked loop (ADPLL) Time-to-Digital Converter (TDC)
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Phase-Locked Loop Based Cancellation of ECG Power Line Interference
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作者 LI Taihao ZHOU Jianshe +2 位作者 LIU Shupeng SHI Jinsheng REN Fuji 《ZTE Communications》 2018年第1期47-51,共5页
Power line(PL)interference is one significant artifact in electrocardiography(ECG)that needs to be reduced to ensure accurate recording of cardiac signals.Because PL interference is non-stationary and has varying freq... Power line(PL)interference is one significant artifact in electrocardiography(ECG)that needs to be reduced to ensure accurate recording of cardiac signals.Because PL interference is non-stationary and has varying frequency,phase,and amplitude in ECG measurement,adaptive techniques are often necessary to track and cancel the interference.In this paper we present a phase-locked loop(PLL)-based adaptive filter to cancel PL interference.The PLL obtains the reference signal that is fed into the adaptive filter to remove the PL interference at the central frequency of 50 Hz.It is found that the technique can effectively cancel PL interference in real ECG signals and,when compared with some existing techniques such as least mean squares(LMS)adaptive filter,the new technique produces better results in terms of signal-to-interference ratio(SIR). 展开更多
关键词 phase-locked loop ECG adaptive FILTER power line cancella-tion
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Hybrid phase-locked loop with fast locking time and low spur in a 0.18-μm CMOS process
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作者 朱思衡 司黎明 +2 位作者 郭超 史君宇 朱卫仁 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第7期748-753,共6页
We propose a novel hybrid phase-locked loop (PLL) architecture for overcoming the trade-off between fast locking time and low spur. To reduce the settling time and meanwhile suppress the reference spurs, we employ a... We propose a novel hybrid phase-locked loop (PLL) architecture for overcoming the trade-off between fast locking time and low spur. To reduce the settling time and meanwhile suppress the reference spurs, we employ a wide-band single-path PLL and a narrow-band dual-path PLL in a transient state and a steady state, respectively, by changing the loop bandwidth according to the gain of voltage controlled oscillator (VCO) and the resister of the loop filter. The hybrid PLL is implemented in a 0.18-μm complementary metal oxide semiconductor (CMOS) process with a total die area of 1.4×0.46 mm2. The measured results exhibit a reference spur level of lower than -73 dB with a reference frequency of 10 MHz and a settling time of 20 μs with 40 MHz frequency jump at 2 GHz. The total power consumption of the hybrid PLL is less than 27 mW with a supply voltage of 1.8 V. 展开更多
关键词 phase-locked loop (PLL) fast locking time low spur complementary metal oxide semiconductor(CMOS)
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Comparative Study of Low-Pass Filter and Phase-Locked Loop Type Speed Filters for Sensorless Control of AC Drives
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作者 Dong Wang Kaiyuan Lu +1 位作者 Peter Omand Rasmussen Zhenyu Yang 《CES Transactions on Electrical Machines and Systems》 2017年第2期207-215,共9页
High quality speed information is one of the key issues in machine sensorless drives,which often requires proper filtering of the estimated speed.This paper comparatively studies typical low-pass filters(LPF)and phase... High quality speed information is one of the key issues in machine sensorless drives,which often requires proper filtering of the estimated speed.This paper comparatively studies typical low-pass filters(LPF)and phase-locked loop(PLL)type filters with respect to ramp speed reference tracking and steady-state performances,as well as the achievement of adaptive cutoff frequency control.An improved LPF-based filter structure with no ramping and steady-state errors caused by filter parameter quantization effects is proposed,which is suitable for applying LPF for sensorless drives of AC machines,especially when fixed-point digital signal processor is selected e.g.in mass production.Furthermore,the potential of adopting PLL for speed filtering is explored.It is demonstrated that PLL type filters can well maintain the advantages offered by the improved LPF.Moreover,it is found that the PLL type filters exhibit almost linear relationship between the cutoff frequency of the PLL filter and its proportional-integral(PI)gains,which can ease the realization of speed filters with adaptive cutoff frequency for improving the speed transient performance.The proposed filters are verified experimentally.The PLL type filter with adaptive cutoff frequency can provide satisfactory performances under various operating conditions and is therefore recommended. 展开更多
关键词 Adaptive cutoff frequency low-pass filter machine sensorless drive phase-locked loop speed filter static error
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Dynamic Free-Spectral-Range Measurement for Fiber Resonator Based on Digital-Heterodyne Optical Phase-Locked Loop
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作者 Hongchen Jiao Tao Wang +2 位作者 Heli Gao Lishuang Feng Honghao Ma 《Optics and Photonics Journal》 2021年第8期332-340,共9页
<div style="text-align:justify;"> We propose a novel scheme, based on digital-heterodyne optical phase-locked loop with whole-fiber circuit, to dynamically measure the free-spectral-range of a fiber re... <div style="text-align:justify;"> We propose a novel scheme, based on digital-heterodyne optical phase-locked loop with whole-fiber circuit, to dynamically measure the free-spectral-range of a fiber resonator. The optical phase-locked loop is established with a differential frequency-modulation module consists of a pair of acousto-optic modulators. The resonance-tracking loop is derived with the Pound-Drever-Hall technique for locking the heterodyne frequency of the OPLL on the frequency difference between adjacent resonance modes. A stable locking accuracy of about 7 × 10<sup>?9</sup> and a dynamic locking accuracy of about 5 × 10<sup>?8</sup> are achieved with the FSR of 8.155 MHz, indicating a bias stability of the resonator fiber optic gyro of about 0.1?/h with 10 Hz bandwidth. In addition, the thermal drift coefficient of the FSR is measured as 0.1 Hz/?C. This shows remarkable potential for realizing advanced optical measurement systems, such as the resonant fiber optic gyro, and so on. </div> 展开更多
关键词 Free Spectral Range Fiber Resonator Dynamic Measurement Digital-Heterodyne Optical phase-locked loop Resonant Fiber Optic Gyro
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A sapphire fibre thermal probe based on fast Fourier transform and phase-lock loop
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作者 王平田 王冬生 +1 位作者 葛文谦 崔立超 《Chinese Physics B》 SCIE EI CAS CSCD 2006年第5期975-979,共5页
A sapphire fibre thermal probe with Cr^3+ ion-doped end is developed by using the laser heated pedestal growth method. The fluorescence thermal probe offers advantages of compact structure, high performance and abili... A sapphire fibre thermal probe with Cr^3+ ion-doped end is developed by using the laser heated pedestal growth method. The fluorescence thermal probe offers advantages of compact structure, high performance and ability to withstand high temperature in a detection range from room temperature to 450℃. Based on the fast Fourier transform (FFT), the fluorescence lifetime is obtained from the tangent function of phase angle of the non-zeroth terms in the FFT result. This method has advantages such as quick calculation, high accuracy and immunity to the background noise. This FFT method is compared with other traditional fitting methods, indicating that the standard deviation of the FFT method is about half of that of the Prony method and about 1/6 of that of the log-fit method. And the FFT method is immune to the background noise involved in a signal. So, the FFT method is an excellent way of processing signals. In addition, a phase-lock amplifier can effectively suppress the noise. 展开更多
关键词 fluorescence thermometer fast Fourier transform phase-lock loop sapphire optical fibre
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A High-Speed Dual Modulus Prescaler Using 0.25 μm CMOS Technology
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作者 杨文荣 曹家麟 +1 位作者 冉峰 王健 《Journal of Shanghai University(English Edition)》 CAS 2004年第3期342-347,共6页
A high-speed dual-modulus divide-by-32/33 prescaler has been developed using 0.25 μm CMOS technology. The source-coupled logic (SCL) structure is used to reduce the switching noise and to ameliorate the power-speed t... A high-speed dual-modulus divide-by-32/33 prescaler has been developed using 0.25 μm CMOS technology. The source-coupled logic (SCL) structure is used to reduce the switching noise and to ameliorate the power-speed tradeoff. The proposed prescaler can operate at high frequency with a low-power consumption. Based on the 2.5 V, 0.25 μm CMOS model, simulation results indicate that the maximum input frequency of the prescaler is up to 3.2 GHz. Running at 2.5 V, the circuit consumes only 4.6 mA at an input frequency 2.5 GHz. 展开更多
关键词 CMOS PRESCALER source-coupled logic(SCL) phase-locked loop(PLL).
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Indorama Ventures和Loop Technologies将组建合资企业从塑料废料生产PET树脂和聚酯纤维
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作者 钱伯章 《聚酯工业》 CAS 2019年第1期62-62,共1页
Indorama Ventures公司通过其子公司美国Indorama Ventures控股公司与可持续塑料树脂和聚酯的技术创新者加拿大Loop工业公司于2018年9月25日达成协议,组建一家平等拥有的合资企业Indorama Loop Technologies公司(ILT),将从饮料和消费品... Indorama Ventures公司通过其子公司美国Indorama Ventures控股公司与可持续塑料树脂和聚酯的技术创新者加拿大Loop工业公司于2018年9月25日达成协议,组建一家平等拥有的合资企业Indorama Loop Technologies公司(ILT),将从饮料和消费品公司的塑料废料生产聚对苯二甲酸乙二醇酯(PET)树脂和聚酯纤维。该合作伙伴关系汇集了Indorama Venture的制造足迹和Loop的专有技术。ILT将拥有全球独家许可. 展开更多
关键词 聚酯纤维 聚对苯二甲酸乙二醇酯 loop technologIES Indorama Ventures PET
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CHAOS AND BIFURCATION OF PHASE-LOCKING LOOPS UNDER PERIODIC PERTURBATION
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作者 郭瑞海 袁晓凤 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 1989年第11期1081-1089,共9页
This paper discusses the chaos and bifurcation for equation x+cosxx+asinx =ebsint. By use of the Melnikov method the conditions to have the chaotic behavior and to have subharmonic oscillations are given.
关键词 CHAOS AND BIFURCATION OF phase-lockING loopS UNDER PERIODIC PERTURBATION
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Development and Applications of Simulation Technology 被引量:1
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作者 WangZicai 《工程科学(英文版)》 2004年第2期33-37,共5页
The developing process of simulation technology is discussed in view of its development, maturation and further development. The applications of simulation technology in the fields of national economy are introduced. ... The developing process of simulation technology is discussed in view of its development, maturation and further development. The applications of simulation technology in the fields of national economy are introduced. Finally, the level and status quo of simulation technology home and overseas are analyzed, and its future trend in the new century is presented. 展开更多
关键词 系统仿真 分布式相互模拟 军事领域 工业 武器设备 仿真技术 计算机 网络技术
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利用智慧化管理平台实现患者护理服务体验的闭环管理
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作者 张育红 张玉侠 +3 位作者 陈潇 韩彭飞 陈建友 杨春 《中国卫生质量管理》 2024年第7期17-21,共5页
持续提升患者就医体验是进一步改善护理服务行动计划的目的。为破解传统患者体验调查方式存在的患者参与率低、问卷有效率低、测评结果无法及时反馈、测评数据无法充分利用等问题,基于技术接受模型理论和“以人为中心”的理念,设计和优... 持续提升患者就医体验是进一步改善护理服务行动计划的目的。为破解传统患者体验调查方式存在的患者参与率低、问卷有效率低、测评结果无法及时反馈、测评数据无法充分利用等问题,基于技术接受模型理论和“以人为中心”的理念,设计和优化住院患者护理服务体验智慧化管理平台,通过患者体验测评短信自动触发、患者体验数据自动分析与反馈、针对性改进计划提交,实现了患者体验“测评-反馈-提升”闭环管理,改善了患者护理服务体验。 展开更多
关键词 患者体验 护理服务 智慧化管理 闭环管理 技术接受模型
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基于半实物仿真工厂的化工生产技术课程教学改革实践研究
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作者 刘立新 于跃龙 《化工设计通讯》 CAS 2024年第7期74-76,共3页
针对现行高职院校化工生产技术课程教学内容情境性不强、教学方法学生主体地位体现不够、考核评价体系数字化程度不足等问题,将半实物仿真工厂引入课程教学中,通过在其营造的“实装、实岗、实操”的职业情境中优化课程教学内容、教学方... 针对现行高职院校化工生产技术课程教学内容情境性不强、教学方法学生主体地位体现不够、考核评价体系数字化程度不足等问题,将半实物仿真工厂引入课程教学中,通过在其营造的“实装、实岗、实操”的职业情境中优化课程教学内容、教学方法和评价体系,推动课程的教学效果。 展开更多
关键词 半实物仿真工厂 化工生产技术课程 教学改革 数字化教学
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A low spur,low jitter 10-GHz phase-locked loop in 0.13-μm CMOS technology
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作者 梅年松 孙瑜 +3 位作者 陆波 潘姚华 黄煜梅 洪志良 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2011年第3期100-104,共5页
This paper presents a 10-GHz low spur and low jitter phase-locked loop(PLL).An improved low phase noise VCO and a dynamic phase frequency detector with a short delay reset time are employed to reduce the noise of th... This paper presents a 10-GHz low spur and low jitter phase-locked loop(PLL).An improved low phase noise VCO and a dynamic phase frequency detector with a short delay reset time are employed to reduce the noise of the PLL.We also discuss the methodology to optimize the high frequency prescaler’s noise and the charge pump’s current mismatch.The chip was fabricated in a SMIC 0.13-μm RF CMOS process with a 1.2-V power supply.The measured integrated RMS jitter is 757 fs(1 kHz to 10 MHz);the phase noise is-89 and-118.1 dBc/Hzat 10kHz and 1 MHz frequency offset,respectively;and the reference frequency spur is below -77 dBc.The chip size is 0.32 mm2 and the power consumption is 30.6 mW. 展开更多
关键词 phase-locked loop VCO charge pump current mismatch
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脑卒中神经环路研究技术进展
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作者 陈彦熹 徐志栋 +3 位作者 刘婷婷 马连素 孙芳玲 王文 《中国比较医学杂志》 CAS 北大核心 2024年第4期114-122,128,共10页
神经环路由神经元之间通过突触结构相互连接而形成,是大脑信息传递和处理的基本单元,在神经功能调控中发挥重要作用。卒中后,脑梗死区域及梗死周围区域与远程区域的神经连接受损,导致患者出现神经功能障碍甚至残疾。然而,随着检测技术进... 神经环路由神经元之间通过突触结构相互连接而形成,是大脑信息传递和处理的基本单元,在神经功能调控中发挥重要作用。卒中后,脑梗死区域及梗死周围区域与远程区域的神经连接受损,导致患者出现神经功能障碍甚至残疾。然而,随着检测技术进步,越来越多研究已证实卒中患者在慢性期时能产生一定的功能恢复,可能与突触连接和神经环路的重新建立有关。因此,开发特定的技术来识别和操纵神经元活动模式,以及使用高时空分辨率成像策略解读这些神经变化过程,使我们能够了解卒中恢复的全脑网络动力学和神经环路重建的发生机制,从神经生物学角度理解卒中病理学发展到行为结果的闭环关系。目前研究神经环路的技术主要集中于光遗传学、化学遗传学、在体钙成像和功能磁共振成像技术。本文将介绍这4种主要技术的工作原理,重点总结各自在解析卒中后神经重塑研究中的应用成果,并简要分析了每种技术的应用场景、优劣性和未来发展趋势,帮助临床及基础研究人员利用这些技术发现新的治疗策略以及评估康复策略的有效性。 展开更多
关键词 卒中 神经环路 光遗传学 化学遗传学 成像技术
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