Planarians provide the ideal model for studying eye development,with their simple eye structure and exceptionally rapid regeneration.Here,we observed the eye morphogenesis,photophobic behavior,spectral sensitivity and...Planarians provide the ideal model for studying eye development,with their simple eye structure and exceptionally rapid regeneration.Here,we observed the eye morphogenesis,photophobic behavior,spectral sensitivity and expression pattern of Djopsin in the freshwater planarian Dugesia japonica.The results showed that:(i)Djopsin encoding the putative protein belonged to the rhabdomeric opsins group and displayed high conservation during animal evolution;(ii)planarians displayed diverse photophobic response to different visible wavelengths and were more sensitive to light blue(495 nm)and yellow(635 nm);(iii)the morphogenesis and functional recovery of eyes were related to the expression pattern of Djopsin during head regeneration;and(iv)Djopsin gene plays a major role in functional recovery during eye regeneration and visual system maintenance in adult planarians.展开更多
基金supported by grants from the National Natural Science Foundation of China(Nos.31570376,31471965 and 31170357)the PhD Programs Foundation of the Ministry of Education of China(No.200804760003)+2 种基金the Innovation Foundation of Henan Province(No.2005126)the Basic and Advanced Technique Research Program of Technology Department of Henan Province(Nos.122300410142,142300410160)the College Students’Innovative Project(No.201410476066).
文摘Planarians provide the ideal model for studying eye development,with their simple eye structure and exceptionally rapid regeneration.Here,we observed the eye morphogenesis,photophobic behavior,spectral sensitivity and expression pattern of Djopsin in the freshwater planarian Dugesia japonica.The results showed that:(i)Djopsin encoding the putative protein belonged to the rhabdomeric opsins group and displayed high conservation during animal evolution;(ii)planarians displayed diverse photophobic response to different visible wavelengths and were more sensitive to light blue(495 nm)and yellow(635 nm);(iii)the morphogenesis and functional recovery of eyes were related to the expression pattern of Djopsin during head regeneration;and(iv)Djopsin gene plays a major role in functional recovery during eye regeneration and visual system maintenance in adult planarians.
