MicroRNAs(miRNAs)are small noncoding RNA molecules ubiquitously distributed across diverse organisms,serving as pivotal regulators of genetic expression.Notably,plant-derived miRNAs have been demonstrated to have uniq...MicroRNAs(miRNAs)are small noncoding RNA molecules ubiquitously distributed across diverse organisms,serving as pivotal regulators of genetic expression.Notably,plant-derived miRNAs have been demonstrated to have unique bioactivity and certain stability in mammalian systems,thereby facilitating their capacity for cross-kingdom modulation of gene expression.While there is substantial evidence supporting the regulation of mammalian cells by plant-derived miRNAs,several questions remain unanswered.Specifically,a comprehensive investigation of the mechanisms underlying the stability and transport of plant miRNAs and their cross-kingdom regulation of gene expression in mammals remains to be done.In this review,we summarized the origin,processing,and functional mechanisms of plant miRNAs in mammalian tissues and circulation,emphasizing their greater resistance to mammalian digestion and circulation systems compared to animal miRNAs.Additionally,we introduce four well-known plant miRNAs that have been extensively studied for their functions and mechanisms in mammalian systems.By delving into these aspects,we aim to offer a fundamental understanding of this intriguing field and shed light on the complex interactions between plant miRNAs and mammalian biology.展开更多
Natural antiseptic formulas are increasingly favored by consumers. This article take preservatives compounded from cinnamon, sophora flavescens and other plant extracts as the main research object, evaluated its antib...Natural antiseptic formulas are increasingly favored by consumers. This article take preservatives compounded from cinnamon, sophora flavescens and other plant extracts as the main research object, evaluated its antibacterial efficacy and application in cosmetics, expect that it can be used in cosmetics to replace conventional chemical preservatives. Research on its antibacterial efficacy through inhibition zone and MIC experiment, and product application research used anti-corrosion challenge and antibacterial rate experiment. The results showed that the plant-derived antiseptic system had a broad antibacterial spectrum, inhibition of 10 different common pathogenic bacteria, and had a very significant inhibitory effect on Gram-positive bacteria and fungi;Among them, the diameter of the antibacterial circle for Bacillus subtilis and Aspergillus niger can reached 31.89 mm and 28.26 mm, while the MIC value was 0.4 mg/mL and 0.8 mg/mL. The spray product with 1.5% addition amount successfully passed the anti-corrosion challenge test and meets the anti-corrosion standard requirements;The 2% added amount of disposable gel product has an inhibitory rate of 51.05% and 70.74% against Escherichia coli and Staphylococcus aureus within 20 minutes of action. In summary, the plantderived compound preservative has ability to be used in cosmetic preservative systems.展开更多
We developed a novel approach to determine rotenone residues in foodstuffs, by integrating solid-phase extraction (SPE) and liquid chromatography/tandem mass spectrometry (LC-MS/MS) technologies, to achieve high s...We developed a novel approach to determine rotenone residues in foodstuffs, by integrating solid-phase extraction (SPE) and liquid chromatography/tandem mass spectrometry (LC-MS/MS) technologies, to achieve high sensitivity and selectivity. In our method, the solvent extraction with n-hexane-dichloromethane (50:50, v/v) and cleanup with florisil SPE cartridges using ethyl acetate-ethyl ether (25:75, v/v) as eluents provided adequate recovery of rotenone. The detection of rotenone was then carried out by LC-MS/MS using acetonitrile-water with the 0.1% formic acid (w/v) as the mobile phase. The multiple reaction monitoring (MRM) scheme employed in the approach involved the transitions of the precursor ion to three selected product ions, in which one pair for quantification was m/z 395.3 〉 213.2 and the other two pairs for identification were m/z 395.3 〉 192.2 and 395.3 〉 367.0. The limits of quantification (LOQs) of the method ranged from 0.001 to 0.005 mg kg-1 depending on the matrix. Intra- and inter-day precisions (relative standard deviations, RSDs) for rotenone were less than 7.1 and 14.8%, respectively. Results from repetitive analysis suggested good reproducibility of the method for rotenone residue detection. The recoveries at three concentrations (LOQ, 10LOQ and 100LOQ) ranged from 79.3-118.3% in cabbage, potato, onion, carrot, apple, orange, banana, lichee, tea, and Shiitake mushroom. The proposed procedure was then applied to the analysis of 129 real samples collected from Xiamen, Fujian Province, China. The existence of rotenone was found in two tea products with concentrations of 0.012 and 0.016 mg kg-1, respectively. The method has great potential for routine analysis of monitoring rotenone residue in foodstuffs.展开更多
An effective method for the trace analysis of indoxacarb residue in foodstuffs of plant and animal origin [grapefruit, ginger, fresh soybean, bamboo shoot, qing-gen-cai (cruciferous vegetable), chicken, fish, and po...An effective method for the trace analysis of indoxacarb residue in foodstuffs of plant and animal origin [grapefruit, ginger, fresh soybean, bamboo shoot, qing-gen-cai (cruciferous vegetable), chicken, fish, and pork] was developed using gas chromatography (GC-ECD) and liquid chromatography tandem mass spectrometry (LC-MS/MS). Samples were extracted using acetone and n-hexane mixed solvent (1:2, v/v) and then purified using solid-phase extraction (SPE) columns. The extracts were analyzed using GC-ECD and LC-MS/MS. The multiple reaction monitoring (MRM) scheme used involved transitions of the precursor ions to selected two product ions in which one pair for identification was m/z 529 → 293 and another pair for quantification was m/z 529 → 249. The detection limits (LODs) of the method were 0.0015 and 0.0006 mg kg^-1, and the quantification limits (LOQs) were 0.005 and 0.002 mg kg^-1 for GC-ECD and LC-MS/MS, respectively. The relative standard deviations (RSDs) of recovery for indoxacarb were lower than 15% in 10 types of agro-products. Ten repetitive determinations of recovery achieved good reproducibility for indoxacarb and the recovery ranged from 72.08 to 113.74%. The proposed procedure was applied to the analysis of several real samples of different origin from Fujian Province, China, and 299 samples were screened for indoxacarb residue, of which 5 positive samples were found.展开更多
Nanotechnologies have been successfully applied to the treatment of various diseases.Plant-derived exosome-like nanoparticles (PENs) are expected to become effective therapeutic modalities for treating disease or in d...Nanotechnologies have been successfully applied to the treatment of various diseases.Plant-derived exosome-like nanoparticles (PENs) are expected to become effective therapeutic modalities for treating disease or in drug-delivery. PENs are minimally cytotoxic to healthy tissues, with which they show excellent biocompatibility, and are biased towards tumors by targeting specific tissues through special endocytosis mechanisms. Thus, the use of these PENs may expand the scope of drug therapies while reducing the off-target effects.In this review, we summarize the fundamental features and bioactivities of PENs extracted from the grape, grapefruit, ginger, lemon, and broccoli and discuss the applications of these particles as therapeutics and nanocarriers.展开更多
There is still no effective means to analyze in depth and utilize domestic mass data about agricultural product quality safety tests in china now. The neural network algorithm, the classification regression tree algor...There is still no effective means to analyze in depth and utilize domestic mass data about agricultural product quality safety tests in china now. The neural network algorithm, the classification regression tree algorithm, the Bayesian network algorithm were selected according to the principle of selecting combination model and were used to build models respectively and then combined, innovatively establishing a combination model which has relatively high precision, strong robustness and better explanatory to predict the results of perishable food transportation meta-morphism monitoring. The relative optimal prediction model of the perishable food transportation metamorphism monitoring system could be got. The relative perfect prediction model can guide the actual sampling work about food quality and safety by prognosticating the occurrence of unqualified food to select the typical and effective samples for test, thus improving the efficiency and effectiveness of sampling work effectively, so as to avoid deteriorated perishable food’s approaching the market to ensure the quality and safety of perishable food transportation. A solid protective wall was built in the protection of general perishable food consumers’ health.展开更多
Fungal and mycotoxin contamination has been found in fordstuffs from Cixian County, an area with a high incidence of esophageal carcinoma (Eca). To set a scientific foundation for the prevention of Eca at the etiologi...Fungal and mycotoxin contamination has been found in fordstuffs from Cixian County, an area with a high incidence of esophageal carcinoma (Eca). To set a scientific foundation for the prevention of Eca at the etiological level, fungal and mycotoxin contaminations of local foodstuffs in Cixian County were analyzed using classical fungal culture methods and HPLC. From 1990 to 1994, 220 corn/wheat samples and 34 corn samples were studied. As a control, 26 corn samples collected from a relatively low incidence area of Eca in Zanhuang County were analyzed for mycotoxins in 1990. The results showed that fungal contamination in corn and wheat was severe and that several of the predominant contaminating fungi such as Furasium moniliforme, etc. were carcinogenic. HPLC results showed that the detection rate and mean content of the mycotoxin sterigmatocystin (ST) in the mountainous area (5/8; 9. 14 μg/kg) were significantly higher than those in the hilly (0; 0) and plain areas (1/18; 1. 29 μg/kg) as well as in low risk area control samples (3/26; 0. 76 μg/kg). Detection rates of deoxynivalenol (DON) in mountainous and hilly areas (5/8, 4/8 respectively) were slightly higher than that in plain area (8/18), while the mean content of DON in the plain area was significantly higher (90. 45-170. 22 vs 50. 56 and 46. 45 μg/kg).Among the different aflatoxins, AFB1 was detected in samples from the two villages in the plain area for the subsequent two years. The mean content of AFB1 was 0. 0183μg/kg, and the highest level was 0. 0497 μg/kg. No AFB1 was detected in the samples from mountainous and hilly areas. AFG1 was detected in more than half of all the samples, and its concentration ranged from 8. 77 to 46. 51 ng/kg. No AFG2 was found in the samples. Thus, the results suggest that at present, fungal and mycotoxin contamination of foodstuffs in Cixian County are quite common.展开更多
This study was to find out the suitable application amount of plant-derived humic acid organic fertilizer for selenium-rich rice production in northern Guilin area by applying the fertilizer at different amounts.The r...This study was to find out the suitable application amount of plant-derived humic acid organic fertilizer for selenium-rich rice production in northern Guilin area by applying the fertilizer at different amounts.The results showed that plant-derived humic acid organic fertilizer could effectively activate selenium in selenium-rich soil,and then promote the uptake of selenium by rice.With costs,selenium enrichment and rice yield as the main evaluation indicators,A4 was chosen as the best treatment,that is,the application of 4 500 kg/hm^2 of plant-derived humic acid organic fertilizer as base fertilizer could achieve the best benefit.展开更多
The natural radioactivities in three major groups of foodstuff widely consumed in Upper Egypt were de- termined. The specific activities of 226Ra, 232Th, and 40K in cereals, leguminosae, and flour were measured using ...The natural radioactivities in three major groups of foodstuff widely consumed in Upper Egypt were de- termined. The specific activities of 226Ra, 232Th, and 40K in cereals, leguminosae, and flour were measured using γ-ray spectroscopy. Another group of hay, water, and soil samples from the same location were also analyzed. Hay samples were found to contain the highest radioactivity concentration among all the samples that were investigated. This in- crement could be due to the high water content in the shoots which tends to accumulate soluble radionuclides. The average calculated concentrations of soil samples in the present study exhibits the lowest values with respect to those from different countries. In the case of water samples, the average activities of both 232Th and 40K were similar to those for soil while 226Ra was twice that of water sample. The annual ingestion dose from each radionuclide was cal- culated. The computed annual dose owing to daily intake of radium, thorium, and potassium via wheat flour, lentils, and bean in the present study (214.8 μSv) is ten times lower than the global average annual radiation dose (2400 μSv) from the natural radiation sources as proposed by UNSCEAR. The obtained results show that the dose values are quite low and carry insignificant radiation dose to the public.展开更多
Retinoblastoma(RB)is a highly aggressive ocular tumor,and due to socioeconomic and medical constraints,many children receive treatment only in the metaphase and advanced clinical stages,resulting in high rates of blin...Retinoblastoma(RB)is a highly aggressive ocular tumor,and due to socioeconomic and medical constraints,many children receive treatment only in the metaphase and advanced clinical stages,resulting in high rates of blindness and disability.Although several approaches exist in the treatment of RB,some children with the disease do not have satisfactory results because of various factors.Plantderived natural products have shown definite therapeutic effects in the treatment of various tumors and are also widely used in the study of RB.We review plant-derived natural products used in the study of anti-RB to provide ideas for the clinical application of these drugs and the development of new therapeutic drugs.展开更多
<span style="font-family:'';font-size:10pt;"><span style="font-size:12px;font-family:Verdana;">Pathogenic spore-forming bacteria pose high risks to healthcare settings, as well ...<span style="font-family:'';font-size:10pt;"><span style="font-size:12px;font-family:Verdana;">Pathogenic spore-forming bacteria pose high risks to healthcare settings, as well as in the food and beverage industries. We reported recently that novel alcohol-based formulations containing plant-derived compounds, including epigallocatechin-3-gallate-palmitate (EGCG-P), a green tea polyphenol ester, provide > 99.99% inactivation of bacterial spores within 60 sec. Based on recently published data from our group and others, we hypothesize that a combination of EGCG-P and alcohol formulated with other plant-derived ingredients would achieve high sporicidal efficacy against a wide spectrum of bacterial spores and can provide novel hand hygiene methods against bacterial spores without toxicity. The objectives of the current study were to optimize </span><span style="font-size:12px;font-family:Verdana;">two novel formulations with combinations of glycerol, citric acid, and EGCG-P</span><span style="font-size:12px;font-family:Verdana;"> to increase sporicidal activity and explore the rapid inactivation mechanisms and suitability for sporicidal products with broad-spectrum activities against aerobic and anaerobic bacterial spores. Methods included suspension testing of two formulations against spores from </span><i><span style="font-size:12px;font-family:Verdana;">Bacillus cereus</span></i><span style="font-size:12px;font-family:Verdana;"> and </span><i><span style="font-size:12px;font-family:Verdana;">Clostridium sporogenes</span></i><span style="font-size:12px;font-family:Verdana;">, quantification of spore germination, and scanning electron microscopy. The results demonstrated that these novel formulations were able to reduce spore germination by >99.999% after 30 sec exposure in </span><span style="font-size:12px;font-family:Verdana;">suspension tests, and rapidly caused physical damage to the spores. Additional</span></span><span style="font-family:'';font-size:10pt;"> </span><span style="line-height:1.5;font-family:Verdana;">studies</span><span style="font-family:'';font-size:10pt;"> </span><span style="line-height:1.5;font-family:Verdana;">are </span><span style="line-height:1.5;font-family:Verdana;">warranted to determine the suitability of the novel formulations for future hand hygiene use.展开更多
Zhejiang, situated in the Yangtze delta and neighbouring Shanghai, is widely known for fish and rice production. The Zhejiang Provincial Cereals, Oils and Foodstuffs I/E Co. Ltd. formerly Zhejiang provincial Cereals, ...Zhejiang, situated in the Yangtze delta and neighbouring Shanghai, is widely known for fish and rice production. The Zhejiang Provincial Cereals, Oils and Foodstuffs I/E Co. Ltd. formerly Zhejiang provincial Cereals, Oils and Foodstuffs I/E Company, is one of the largest foreign trade shareholding enterprises in Zhejiang Province. It展开更多
Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the osteoporosis.More and more evidences proved that plant-derived polysaccharides could have a rema...Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the osteoporosis.More and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts,exerting anti-osteoporosis effects.According to the previous research,the extract of Cibotium barumoz,Achyranthes bidentata,Curculigo orchioides,Epimedium brevicornum,Angelica sinensis,Polygonatum sibiricum,Dendrobium officinale,Morinda officinalis,Nelumbo mucifera,Diospyros kaki,Hordeum vulgare,Cistanche deserticola,Commiphora Myrrha and other plant-derived polysaccharides could benefit to the osteoblasts and osteoclasts.The essential mechanisms are mainly related to the activation or inhibition of many factors,including runt-related transcription factor 2(Runx2),B-catenin,osterix(Osx),activator protein-1(AP-1),osteocalcin(OCN/BGP),alkaline phosphatase(ALP),osteopontin(OPN),bone morphogenetic protein(BMP),phosphatidylinositol 3-kinase(PI3K)/C-Jun N-terminal kinase(JNK)/extracellular regulated protein kinase(ERK),osteoprotegerin(OPG),receptor activator of nuclear factor-kB(RANK),monocyte/macrophage colony-stimulating factor(M-CSF),tumor necrosis factor receptor-associated factor 6(TRAF-6),receptor activator of nuclear factor(NF)-KB ligand(RANKL),nuclear factor of activated T cells 1(NFATc1),c-Fos,matrix metallopeptidase-9(MMP-9),glycogen synthase kinase 3β(GSK3B)/B-catenin,nuclear factor E2-related factor 2(Nf2),as well as these related pathways,such as Wnt/p-catenin,BMP-2/SMAD1/5/8,PI3K/AKT,OPG/RANKL/RANK,NF-κB,MAPKs,etc.These plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its formation.The reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.展开更多
Heilongjiang Province is an important marketable grain depot in China. Since the reform and opening up, Heilongjiang Province production capacity of foodstuff is increasingly growing into a new level. This paper start...Heilongjiang Province is an important marketable grain depot in China. Since the reform and opening up, Heilongjiang Province production capacity of foodstuff is increasingly growing into a new level. This paper started with the actuality of Heilongjiang Province integrated production capacity of foodstuff, and analyzed its major factors empirically through the mathematical model, then proposed some measures to enhance Heilongjiang Province production capacity of foodstuff which ensured China foodstuff security展开更多
基金supported by grants from the Ministry of Science and Technology of the People’s Republic of China(2018YFA0507101,2021YFA1300301)the Beijing Natural Science Foundation(5215016)。
文摘MicroRNAs(miRNAs)are small noncoding RNA molecules ubiquitously distributed across diverse organisms,serving as pivotal regulators of genetic expression.Notably,plant-derived miRNAs have been demonstrated to have unique bioactivity and certain stability in mammalian systems,thereby facilitating their capacity for cross-kingdom modulation of gene expression.While there is substantial evidence supporting the regulation of mammalian cells by plant-derived miRNAs,several questions remain unanswered.Specifically,a comprehensive investigation of the mechanisms underlying the stability and transport of plant miRNAs and their cross-kingdom regulation of gene expression in mammals remains to be done.In this review,we summarized the origin,processing,and functional mechanisms of plant miRNAs in mammalian tissues and circulation,emphasizing their greater resistance to mammalian digestion and circulation systems compared to animal miRNAs.Additionally,we introduce four well-known plant miRNAs that have been extensively studied for their functions and mechanisms in mammalian systems.By delving into these aspects,we aim to offer a fundamental understanding of this intriguing field and shed light on the complex interactions between plant miRNAs and mammalian biology.
文摘Natural antiseptic formulas are increasingly favored by consumers. This article take preservatives compounded from cinnamon, sophora flavescens and other plant extracts as the main research object, evaluated its antibacterial efficacy and application in cosmetics, expect that it can be used in cosmetics to replace conventional chemical preservatives. Research on its antibacterial efficacy through inhibition zone and MIC experiment, and product application research used anti-corrosion challenge and antibacterial rate experiment. The results showed that the plant-derived antiseptic system had a broad antibacterial spectrum, inhibition of 10 different common pathogenic bacteria, and had a very significant inhibitory effect on Gram-positive bacteria and fungi;Among them, the diameter of the antibacterial circle for Bacillus subtilis and Aspergillus niger can reached 31.89 mm and 28.26 mm, while the MIC value was 0.4 mg/mL and 0.8 mg/mL. The spray product with 1.5% addition amount successfully passed the anti-corrosion challenge test and meets the anti-corrosion standard requirements;The 2% added amount of disposable gel product has an inhibitory rate of 51.05% and 70.74% against Escherichia coli and Staphylococcus aureus within 20 minutes of action. In summary, the plantderived compound preservative has ability to be used in cosmetic preservative systems.
基金supported by the Fujian Provincial Department of Science and Technology, China(2006F3002)Xiamen Science and Technology Bureau,China (3502Z20072003, 3502Z20092008 and3502Z20092009)Ministry of Agriculture,China (200903034)
文摘We developed a novel approach to determine rotenone residues in foodstuffs, by integrating solid-phase extraction (SPE) and liquid chromatography/tandem mass spectrometry (LC-MS/MS) technologies, to achieve high sensitivity and selectivity. In our method, the solvent extraction with n-hexane-dichloromethane (50:50, v/v) and cleanup with florisil SPE cartridges using ethyl acetate-ethyl ether (25:75, v/v) as eluents provided adequate recovery of rotenone. The detection of rotenone was then carried out by LC-MS/MS using acetonitrile-water with the 0.1% formic acid (w/v) as the mobile phase. The multiple reaction monitoring (MRM) scheme employed in the approach involved the transitions of the precursor ion to three selected product ions, in which one pair for quantification was m/z 395.3 〉 213.2 and the other two pairs for identification were m/z 395.3 〉 192.2 and 395.3 〉 367.0. The limits of quantification (LOQs) of the method ranged from 0.001 to 0.005 mg kg-1 depending on the matrix. Intra- and inter-day precisions (relative standard deviations, RSDs) for rotenone were less than 7.1 and 14.8%, respectively. Results from repetitive analysis suggested good reproducibility of the method for rotenone residue detection. The recoveries at three concentrations (LOQ, 10LOQ and 100LOQ) ranged from 79.3-118.3% in cabbage, potato, onion, carrot, apple, orange, banana, lichee, tea, and Shiitake mushroom. The proposed procedure was then applied to the analysis of 129 real samples collected from Xiamen, Fujian Province, China. The existence of rotenone was found in two tea products with concentrations of 0.012 and 0.016 mg kg-1, respectively. The method has great potential for routine analysis of monitoring rotenone residue in foodstuffs.
基金grants from Fujian Pro- vincial Department of Science and Technology (2006F3002)Xiamen Science and Technology Bureau (3502Z20072003)China Postdoctoral Programme (20060390291)
文摘An effective method for the trace analysis of indoxacarb residue in foodstuffs of plant and animal origin [grapefruit, ginger, fresh soybean, bamboo shoot, qing-gen-cai (cruciferous vegetable), chicken, fish, and pork] was developed using gas chromatography (GC-ECD) and liquid chromatography tandem mass spectrometry (LC-MS/MS). Samples were extracted using acetone and n-hexane mixed solvent (1:2, v/v) and then purified using solid-phase extraction (SPE) columns. The extracts were analyzed using GC-ECD and LC-MS/MS. The multiple reaction monitoring (MRM) scheme used involved transitions of the precursor ions to selected two product ions in which one pair for identification was m/z 529 → 293 and another pair for quantification was m/z 529 → 249. The detection limits (LODs) of the method were 0.0015 and 0.0006 mg kg^-1, and the quantification limits (LOQs) were 0.005 and 0.002 mg kg^-1 for GC-ECD and LC-MS/MS, respectively. The relative standard deviations (RSDs) of recovery for indoxacarb were lower than 15% in 10 types of agro-products. Ten repetitive determinations of recovery achieved good reproducibility for indoxacarb and the recovery ranged from 72.08 to 113.74%. The proposed procedure was applied to the analysis of several real samples of different origin from Fujian Province, China, and 299 samples were screened for indoxacarb residue, of which 5 positive samples were found.
基金supported by the National Natural Science Foundation of China (No. 81773911, 81690263 and 81573616)the Development Project of Shanghai Peak DisciplinesIntegrated Medicine (No. 20180101)。
文摘Nanotechnologies have been successfully applied to the treatment of various diseases.Plant-derived exosome-like nanoparticles (PENs) are expected to become effective therapeutic modalities for treating disease or in drug-delivery. PENs are minimally cytotoxic to healthy tissues, with which they show excellent biocompatibility, and are biased towards tumors by targeting specific tissues through special endocytosis mechanisms. Thus, the use of these PENs may expand the scope of drug therapies while reducing the off-target effects.In this review, we summarize the fundamental features and bioactivities of PENs extracted from the grape, grapefruit, ginger, lemon, and broccoli and discuss the applications of these particles as therapeutics and nanocarriers.
文摘There is still no effective means to analyze in depth and utilize domestic mass data about agricultural product quality safety tests in china now. The neural network algorithm, the classification regression tree algorithm, the Bayesian network algorithm were selected according to the principle of selecting combination model and were used to build models respectively and then combined, innovatively establishing a combination model which has relatively high precision, strong robustness and better explanatory to predict the results of perishable food transportation meta-morphism monitoring. The relative optimal prediction model of the perishable food transportation metamorphism monitoring system could be got. The relative perfect prediction model can guide the actual sampling work about food quality and safety by prognosticating the occurrence of unqualified food to select the typical and effective samples for test, thus improving the efficiency and effectiveness of sampling work effectively, so as to avoid deteriorated perishable food’s approaching the market to ensure the quality and safety of perishable food transportation. A solid protective wall was built in the protection of general perishable food consumers’ health.
文摘Fungal and mycotoxin contamination has been found in fordstuffs from Cixian County, an area with a high incidence of esophageal carcinoma (Eca). To set a scientific foundation for the prevention of Eca at the etiological level, fungal and mycotoxin contaminations of local foodstuffs in Cixian County were analyzed using classical fungal culture methods and HPLC. From 1990 to 1994, 220 corn/wheat samples and 34 corn samples were studied. As a control, 26 corn samples collected from a relatively low incidence area of Eca in Zanhuang County were analyzed for mycotoxins in 1990. The results showed that fungal contamination in corn and wheat was severe and that several of the predominant contaminating fungi such as Furasium moniliforme, etc. were carcinogenic. HPLC results showed that the detection rate and mean content of the mycotoxin sterigmatocystin (ST) in the mountainous area (5/8; 9. 14 μg/kg) were significantly higher than those in the hilly (0; 0) and plain areas (1/18; 1. 29 μg/kg) as well as in low risk area control samples (3/26; 0. 76 μg/kg). Detection rates of deoxynivalenol (DON) in mountainous and hilly areas (5/8, 4/8 respectively) were slightly higher than that in plain area (8/18), while the mean content of DON in the plain area was significantly higher (90. 45-170. 22 vs 50. 56 and 46. 45 μg/kg).Among the different aflatoxins, AFB1 was detected in samples from the two villages in the plain area for the subsequent two years. The mean content of AFB1 was 0. 0183μg/kg, and the highest level was 0. 0497 μg/kg. No AFB1 was detected in the samples from mountainous and hilly areas. AFG1 was detected in more than half of all the samples, and its concentration ranged from 8. 77 to 46. 51 ng/kg. No AFG2 was found in the samples. Thus, the results suggest that at present, fungal and mycotoxin contamination of foodstuffs in Cixian County are quite common.
基金Supported by the Special Fund for the Construction of Guangxi Innovation Team of China Agriculture Research Systemthe Agricultural Key Science and Technology Project of Guangxi(201621,201604)+6 种基金the Program for the Scientific Research and Technology Development in Guangxi(Guike AD16380194)the Special Fund for the Innovation-Driven Development in Guangxi(Guike AA17202026)the Key Research and Development Program of Guangxi(Guike AB16380207)the Science Research and Technology Development Program of Guilin City(2016011202,20170116-4)the Science Research and Technology Development Program of Nanning City(20165370)the Special Fund for the Collaborative Innovation of Fundamental Research,Guangxi Academy of Agricultural Sciences(Guinongke 2017YZ03)the Fund for Science and Technology Development of Guangxi Academy of Agricultural Sciences(2017JM07)
文摘This study was to find out the suitable application amount of plant-derived humic acid organic fertilizer for selenium-rich rice production in northern Guilin area by applying the fertilizer at different amounts.The results showed that plant-derived humic acid organic fertilizer could effectively activate selenium in selenium-rich soil,and then promote the uptake of selenium by rice.With costs,selenium enrichment and rice yield as the main evaluation indicators,A4 was chosen as the best treatment,that is,the application of 4 500 kg/hm^2 of plant-derived humic acid organic fertilizer as base fertilizer could achieve the best benefit.
文摘The natural radioactivities in three major groups of foodstuff widely consumed in Upper Egypt were de- termined. The specific activities of 226Ra, 232Th, and 40K in cereals, leguminosae, and flour were measured using γ-ray spectroscopy. Another group of hay, water, and soil samples from the same location were also analyzed. Hay samples were found to contain the highest radioactivity concentration among all the samples that were investigated. This in- crement could be due to the high water content in the shoots which tends to accumulate soluble radionuclides. The average calculated concentrations of soil samples in the present study exhibits the lowest values with respect to those from different countries. In the case of water samples, the average activities of both 232Th and 40K were similar to those for soil while 226Ra was twice that of water sample. The annual ingestion dose from each radionuclide was cal- culated. The computed annual dose owing to daily intake of radium, thorium, and potassium via wheat flour, lentils, and bean in the present study (214.8 μSv) is ten times lower than the global average annual radiation dose (2400 μSv) from the natural radiation sources as proposed by UNSCEAR. The obtained results show that the dose values are quite low and carry insignificant radiation dose to the public.
基金Supported by the Scientific Research Fund of Jiangxi Education Department(No.GJJ211224)the Joint Key Project of Yunnan Universities(No.202001BA070001-007)。
文摘Retinoblastoma(RB)is a highly aggressive ocular tumor,and due to socioeconomic and medical constraints,many children receive treatment only in the metaphase and advanced clinical stages,resulting in high rates of blindness and disability.Although several approaches exist in the treatment of RB,some children with the disease do not have satisfactory results because of various factors.Plantderived natural products have shown definite therapeutic effects in the treatment of various tumors and are also widely used in the study of RB.We review plant-derived natural products used in the study of anti-RB to provide ideas for the clinical application of these drugs and the development of new therapeutic drugs.
文摘<span style="font-family:'';font-size:10pt;"><span style="font-size:12px;font-family:Verdana;">Pathogenic spore-forming bacteria pose high risks to healthcare settings, as well as in the food and beverage industries. We reported recently that novel alcohol-based formulations containing plant-derived compounds, including epigallocatechin-3-gallate-palmitate (EGCG-P), a green tea polyphenol ester, provide > 99.99% inactivation of bacterial spores within 60 sec. Based on recently published data from our group and others, we hypothesize that a combination of EGCG-P and alcohol formulated with other plant-derived ingredients would achieve high sporicidal efficacy against a wide spectrum of bacterial spores and can provide novel hand hygiene methods against bacterial spores without toxicity. The objectives of the current study were to optimize </span><span style="font-size:12px;font-family:Verdana;">two novel formulations with combinations of glycerol, citric acid, and EGCG-P</span><span style="font-size:12px;font-family:Verdana;"> to increase sporicidal activity and explore the rapid inactivation mechanisms and suitability for sporicidal products with broad-spectrum activities against aerobic and anaerobic bacterial spores. Methods included suspension testing of two formulations against spores from </span><i><span style="font-size:12px;font-family:Verdana;">Bacillus cereus</span></i><span style="font-size:12px;font-family:Verdana;"> and </span><i><span style="font-size:12px;font-family:Verdana;">Clostridium sporogenes</span></i><span style="font-size:12px;font-family:Verdana;">, quantification of spore germination, and scanning electron microscopy. The results demonstrated that these novel formulations were able to reduce spore germination by >99.999% after 30 sec exposure in </span><span style="font-size:12px;font-family:Verdana;">suspension tests, and rapidly caused physical damage to the spores. Additional</span></span><span style="font-family:'';font-size:10pt;"> </span><span style="line-height:1.5;font-family:Verdana;">studies</span><span style="font-family:'';font-size:10pt;"> </span><span style="line-height:1.5;font-family:Verdana;">are </span><span style="line-height:1.5;font-family:Verdana;">warranted to determine the suitability of the novel formulations for future hand hygiene use.
文摘Zhejiang, situated in the Yangtze delta and neighbouring Shanghai, is widely known for fish and rice production. The Zhejiang Provincial Cereals, Oils and Foodstuffs I/E Co. Ltd. formerly Zhejiang provincial Cereals, Oils and Foodstuffs I/E Company, is one of the largest foreign trade shareholding enterprises in Zhejiang Province. It
基金supported by the College students’innovation Project of Henan University(20221020006).
文摘Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the osteoporosis.More and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts,exerting anti-osteoporosis effects.According to the previous research,the extract of Cibotium barumoz,Achyranthes bidentata,Curculigo orchioides,Epimedium brevicornum,Angelica sinensis,Polygonatum sibiricum,Dendrobium officinale,Morinda officinalis,Nelumbo mucifera,Diospyros kaki,Hordeum vulgare,Cistanche deserticola,Commiphora Myrrha and other plant-derived polysaccharides could benefit to the osteoblasts and osteoclasts.The essential mechanisms are mainly related to the activation or inhibition of many factors,including runt-related transcription factor 2(Runx2),B-catenin,osterix(Osx),activator protein-1(AP-1),osteocalcin(OCN/BGP),alkaline phosphatase(ALP),osteopontin(OPN),bone morphogenetic protein(BMP),phosphatidylinositol 3-kinase(PI3K)/C-Jun N-terminal kinase(JNK)/extracellular regulated protein kinase(ERK),osteoprotegerin(OPG),receptor activator of nuclear factor-kB(RANK),monocyte/macrophage colony-stimulating factor(M-CSF),tumor necrosis factor receptor-associated factor 6(TRAF-6),receptor activator of nuclear factor(NF)-KB ligand(RANKL),nuclear factor of activated T cells 1(NFATc1),c-Fos,matrix metallopeptidase-9(MMP-9),glycogen synthase kinase 3β(GSK3B)/B-catenin,nuclear factor E2-related factor 2(Nf2),as well as these related pathways,such as Wnt/p-catenin,BMP-2/SMAD1/5/8,PI3K/AKT,OPG/RANKL/RANK,NF-κB,MAPKs,etc.These plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its formation.The reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.
基金Supported by the Achievement of Program for New Century Excellent Talents in Heilongjiang Province (1153-NCET-004)Project of Postdoctoral Scientific Research Launch Foundation in Heilongjiang Province
文摘Heilongjiang Province is an important marketable grain depot in China. Since the reform and opening up, Heilongjiang Province production capacity of foodstuff is increasingly growing into a new level. This paper started with the actuality of Heilongjiang Province integrated production capacity of foodstuff, and analyzed its major factors empirically through the mathematical model, then proposed some measures to enhance Heilongjiang Province production capacity of foodstuff which ensured China foodstuff security