Objective To explore the application effect of time tracking platform in improving the reperfusion treatment of patients with acute ischemic stroke in primary hospitals. Methods and Results Patients with acute ischemi...Objective To explore the application effect of time tracking platform in improving the reperfusion treatment of patients with acute ischemic stroke in primary hospitals. Methods and Results Patients with acute ischemic stroke who carried out emergency intravenous thrombolysis and arterial thrombectomy in our hospital in 2021, 2022 and 2023 were selected. The time tracking mode was implemented, and the patients were recorded at each time node of the hospital and the whole-process digital management was conducted. Compared the mean DNT (Door to Needle Time) of intravenous thrombolysis in emergency stroke patients in 2021, 2022 and 2023, the total number of hospital cases within 4.5 h of onset, the total number of thrombolysis cases within 4.5 h of onset, the number of intravenous thrombolysis in 60 minutes of acute ischemic stroke, and the number of thrombolysis cases. The results show that from 2021 to 2023 our emergency stroke patients with intravenous thrombolysis average DNT shortened year by year, to the hospital within 4.5 h after the onset of the difference is statistically significant (all P < 0.05) conclusion through the application of stroke time tracking platform, is beneficial to shorten the treatment time of each link, can effectively reduce the hospital time delay, improve the rate of thrombolysis, improve the reperfusion of stroke centers in primary hospitals.展开更多
目的:分析基于eStroke影像平台醒后卒中前循环血管取栓的临床预后相关因素。方法:回顾性纳入梧州市工人医院神经内科2018年6月-2022年4月收治的104例醒后卒中前循环梗死患者,经多模式MRI检查上传eStroke影像平台评估后行血管取栓。以术...目的:分析基于eStroke影像平台醒后卒中前循环血管取栓的临床预后相关因素。方法:回顾性纳入梧州市工人医院神经内科2018年6月-2022年4月收治的104例醒后卒中前循环梗死患者,经多模式MRI检查上传eStroke影像平台评估后行血管取栓。以术后90 d改良Rankin量表(mRS)的评分进行分组,mRS评分0~2分为预后良好组(n=46),mRS评分3~5分为预后不良组(n=53)。采用logistic回归模型分析影响醒后卒中前循环血管取栓的临床预后因素。结果:单因素分析示:两组年龄、入院基线美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分、NIHSS-意识评分、24 h神经功能改善、核心梗死体积、DSA侧支循环比较,差异均有统计学意义(P<0.05)。多因素logistic分析结果显示:年龄[OR=1.057,95%CI(1.018,1.098),P=0.004]、NIHSS-意识评分[OR=2.358,95%CI(1.136,4.893),P=0.021]、基线NIHSS评分[OR=0.852,95%CI(0.752,0.965),P=0.012]、24 h神经功能改善[OR=37.763,95%CI(9.964,143.114),P=0.000]DSA侧支循环[OR=0.234,95%CI(0.063,0.868),P=0.030]是影响醒后卒中患者取栓预后的影响因素(P<0.05)结论:基于eStroke影像平台醒后卒中前循环血管取栓临床预后与年龄、NIHSS-意识评分、基线NIHSS评分、24 h神经功能改善、侧支循环情况等多因素有关,临床综合多因素指标更有利于预测醒后卒中取栓预后转归,指导临床治疗。展开更多
Shaking tables with moving platforms are widely used in laboratory testing of structural models and full-sized devices. In most cases, the platform＇s movement should reproduce real ground acceleration records. Howeve...Shaking tables with moving platforms are widely used in laboratory testing of structural models and full-sized devices. In most cases, the platform＇s movement should reproduce real ground acceleration records. However, the stroke of the platform, required for reproduction of real records, is usually rather large. This limitation does not allow an accurate realization of the ground motion by the shaking table. Commonly, in order to overcome this problem, original records are modified, which causes a significant change in the acceleration records＇ spectra. That is why structural responses to the original and to the modified records are different. A new method for modification of original acceleration records is proposed, in which the original record is corrected by an additional artificial one that changes the shaking platform＇s displacement. The corrected record is obtained as a sequence of impulses, The magnitude and duration of each impulse, as well as their location on the time scale, are obtained by an optimization procedure. The optimization is implemented according to a performance index, aimed to minimize the influence of the correcting acceleration record on the specmam of the original one. The proposed method has higher reproduction accuracy, compared to other known methods. Its effectiveness is demonstrated by comparison of response spectra and dynamic behaviors of three multi-story structures subjected to natural and modified seismic excitations.展开更多
文摘Objective To explore the application effect of time tracking platform in improving the reperfusion treatment of patients with acute ischemic stroke in primary hospitals. Methods and Results Patients with acute ischemic stroke who carried out emergency intravenous thrombolysis and arterial thrombectomy in our hospital in 2021, 2022 and 2023 were selected. The time tracking mode was implemented, and the patients were recorded at each time node of the hospital and the whole-process digital management was conducted. Compared the mean DNT (Door to Needle Time) of intravenous thrombolysis in emergency stroke patients in 2021, 2022 and 2023, the total number of hospital cases within 4.5 h of onset, the total number of thrombolysis cases within 4.5 h of onset, the number of intravenous thrombolysis in 60 minutes of acute ischemic stroke, and the number of thrombolysis cases. The results show that from 2021 to 2023 our emergency stroke patients with intravenous thrombolysis average DNT shortened year by year, to the hospital within 4.5 h after the onset of the difference is statistically significant (all P < 0.05) conclusion through the application of stroke time tracking platform, is beneficial to shorten the treatment time of each link, can effectively reduce the hospital time delay, improve the rate of thrombolysis, improve the reperfusion of stroke centers in primary hospitals.
文摘目的:分析基于eStroke影像平台醒后卒中前循环血管取栓的临床预后相关因素。方法:回顾性纳入梧州市工人医院神经内科2018年6月-2022年4月收治的104例醒后卒中前循环梗死患者,经多模式MRI检查上传eStroke影像平台评估后行血管取栓。以术后90 d改良Rankin量表(mRS)的评分进行分组,mRS评分0~2分为预后良好组(n=46),mRS评分3~5分为预后不良组(n=53)。采用logistic回归模型分析影响醒后卒中前循环血管取栓的临床预后因素。结果:单因素分析示:两组年龄、入院基线美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分、NIHSS-意识评分、24 h神经功能改善、核心梗死体积、DSA侧支循环比较,差异均有统计学意义(P<0.05)。多因素logistic分析结果显示:年龄[OR=1.057,95%CI(1.018,1.098),P=0.004]、NIHSS-意识评分[OR=2.358,95%CI(1.136,4.893),P=0.021]、基线NIHSS评分[OR=0.852,95%CI(0.752,0.965),P=0.012]、24 h神经功能改善[OR=37.763,95%CI(9.964,143.114),P=0.000]DSA侧支循环[OR=0.234,95%CI(0.063,0.868),P=0.030]是影响醒后卒中患者取栓预后的影响因素(P<0.05)结论:基于eStroke影像平台醒后卒中前循环血管取栓临床预后与年龄、NIHSS-意识评分、基线NIHSS评分、24 h神经功能改善、侧支循环情况等多因素有关,临床综合多因素指标更有利于预测醒后卒中取栓预后转归,指导临床治疗。
文摘Shaking tables with moving platforms are widely used in laboratory testing of structural models and full-sized devices. In most cases, the platform＇s movement should reproduce real ground acceleration records. However, the stroke of the platform, required for reproduction of real records, is usually rather large. This limitation does not allow an accurate realization of the ground motion by the shaking table. Commonly, in order to overcome this problem, original records are modified, which causes a significant change in the acceleration records＇ spectra. That is why structural responses to the original and to the modified records are different. A new method for modification of original acceleration records is proposed, in which the original record is corrected by an additional artificial one that changes the shaking platform＇s displacement. The corrected record is obtained as a sequence of impulses, The magnitude and duration of each impulse, as well as their location on the time scale, are obtained by an optimization procedure. The optimization is implemented according to a performance index, aimed to minimize the influence of the correcting acceleration record on the specmam of the original one. The proposed method has higher reproduction accuracy, compared to other known methods. Its effectiveness is demonstrated by comparison of response spectra and dynamic behaviors of three multi-story structures subjected to natural and modified seismic excitations.
