Point bars are well developed on the Yellow River delta, an~ which theShengli I point bar is the most typical. The point bar, being about 4 km in length and several tensto more than 100 meters in width, is located on ...Point bars are well developed on the Yellow River delta, an~ which theShengli I point bar is the most typical. The point bar, being about 4 km in length and several tensto more than 100 meters in width, is located on the south side of the Shengli Bridge in KenliCounty, Dongying, Shandong. It is a typical fine-grained point bar with silt, which is predominant,some clay and minor plant debris and clay boulders. The Shengli I Point bar has complicated 3-Dstructures. Firstly, in a plane view, it comprises mainly eight sedimentary units, bar edge, baredge, bar platform, bar plain, bar channel, bar gully, bar pond and bar bay, developing side by sideand superimposed one by one m a complex way. Secondly, its vertical structures are very complex dueto the partial superimposition of the 8 sedimentary units. Besides hydatogenesis, very intensivewind erosion, eolian, ice and meltwater actions are also visible on the Shengli I point bar. Thecomplex form is made even more complicated because of the above co-actions.展开更多
In order to solve dynamic Problems caused by the internal structure of fluvial reservoir,it is necessa-ry to study the fine anatomy of Point bar. Taking Minghuazhen Formation in the northern block of Q oilfield, Bohai...In order to solve dynamic Problems caused by the internal structure of fluvial reservoir,it is necessa-ry to study the fine anatomy of Point bar. Taking Minghuazhen Formation in the northern block of Q oilfield, Bohai Sea as an examPle,the authors studied identification marks,distribution Pattern and scale of Point bar based on coring,logging and dynamic data. The results show that the length of Point bar and the width of lateral accretion body are 713-911 m and 71-111m,resPectively;the diP angle and the thickness of lateral accretion bedding are 3. 5o-5. 9o and 0. 1-0. 5 m. The lateral accretion beddings are the key factor affecting the seePage velocity of the tracer.展开更多
Geomorphic dynamics of alluvial rivers in response to upstream damming have substantial impacts on navigation, habitat protection, and channel stability. The purpose of this study was to determine how flow and sedimen...Geomorphic dynamics of alluvial rivers in response to upstream damming have substantial impacts on navigation, habitat protection, and channel stability. The purpose of this study was to determine how flow and sediment regimes, and meander characteristics affect the morphological adjustment of bends in the Lower Jingjiang Reach(LJR) before and after the Three Gorges Project(TGP). Based on detailed field measurements and hydrological and topographic datasets from 1991 to 2016, banks and point bars morphodynamics of 12continuous bends in the LJR were comprehensively analyzed. Point bars in the LJR mainly experienced a net deposition before the TGP operation, but substantially deteriorated with a net erosion rate of 4.6 million m^(3) yr^(-1) in the post-TGP periods(2003–2016), and erosion on heads and upstream margins of point bars was a general adjustment pattern in the 12 bends.The most significant morphological changes of point bars and banks occurred in 2006–2011,indicating a delayed response of the channel evolution of the LJR to damming. Detailed observations suggested that the medium discharges(16,000–18,000 m^(3) s^(-1)) were the most contributive discharges in shaping the morphology of point bars and banks in the LJR after damming. In addition, we revealed the importance of sediment supply on meander deformation of the LJR, driven by sediment exchange over point bars, and more upstream planform deformation tended to occur in bends with high sinuosity(>2.0) in the LJR after damming.The relationship between meander deformation and sinuosity was manifested through the geometric adjustment range of point bars. The morphological adjustments of point bars in the highly curved or compound bends of the LJR were more conducive to cause flow deflections,leading to form concave-bank bars after the TGP operation.展开更多
Precipitation samples collected at Point Barrow, Alaska in the August and September of 1994 was analyzed for pH, conductivity and all major ions. A mean pH value of 5.53 was gained, and the samples' conductiv...Precipitation samples collected at Point Barrow, Alaska in the August and September of 1994 was analyzed for pH, conductivity and all major ions. A mean pH value of 5.53 was gained, and the samples' conductivity showed no linear correlation with its acidity, which did not agree to the similar work results on the Qinghai Tibet Plateau. Cl - and Na + were found to originate mainly with seasalt. The concentrations of SO 2- 4 varied from event to event. But the exSO 2- 4 concentrations remained small, which indicated less anthropogenic effect on the environment at the site.展开更多
BACKGROUND:It has been shown that interleukin-1 (IL-1) may cause inflammatory reactions, which stimulate the nerve root of patients with lumbar intervertebral disc protrusion and leads to pain. Whether the clinical...BACKGROUND:It has been shown that interleukin-1 (IL-1) may cause inflammatory reactions, which stimulate the nerve root of patients with lumbar intervertebral disc protrusion and leads to pain. Whether the clinical curative effects of acupuncture in the treatment of lumbar and leg pain are linked to an inhibition of local IL-1 secretion is unknown. OBJECTIVE: To assess the influence of acupuncture on IL-1, this study was designed to verify the effects of acupuncture at the "Huatuojiaji (Extra)" point on the nerve root in a rat model of lumbar nerve root compression, compared with administration of meloxicam, a non-steroidal anti-inflammatory drug. DESIGN, TIME AND SETTING: Randomized, controlled, molecular biology experiment, performed at the Experimental Center, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University between September 2005 and April 2006. MATERIALS: Forty healthy adult Sprague Dawley rats of either gender were included in this study. The rats were randomly and evenly divided into the following four groups: normal control, model, acupuncture and meloxicam groups. Lumbar nerve root compression was induced in rats in the model, acupuncture, and meloxicam groups by inserting a specially made silicon rubber slice at the juncture of the L5 nerve root and the dural sac. The acupuncture needle (pattern number N3030, 30#, 1.5 inch) was purchased from Suzhou Medical Appliance Factory, China. IL-1 enzyme linked immunosorbent assay (ELISA) kit was purchased from Santa Cruz Biotechnology, Inc., USA. METHODS: The acupuncture group was acupunctured at the "Huatuojiaji" point, which is lateral to the compressed L5-6 nerve root, with an acupuncture depth of 0.5 cm. There were two treatment courses, each of involved seven 20-minute acupuncture sessions, one session a day. The meloxicam group was administered intragastrically 3.75 mg/kg meloxicam (5 mg meloxicam /10 mL physiological saline). Rats in the normal control group and model group received an intragastric administration of 10 mL/kg physiological saline. All administrations were performed once a day. MAIN OUTCOME MEASURES: At day 14 post-surgery, the IL-1 level in the compressed nerve root was determined by a streptavidin-peroxidase (S-P) immunohistochemical method, and IL-1β mRNA expression in the compressed nerve root was simultaneously detected by real-time reverse transcription-polymerase chain reaction. RESULTS: The expression levels of IL-1 and IL-1β mRNA in the L5 nerve root were significantly higher in the model group than in the control group (P 〈 0.01). However, the expression levels of IL-1 and IL-1β mRNA were significantly lower in the acupuncture and meloxicam groups than in the model group (P 〈 0.05–0.01). Expression levels of IL-1 and IL-1β mRNA were significantly higher in the acupuncture group than in the meloxicam group (P 〈 0.01). CONCLUSION: Acupuncture at the "Huatuojiaji" point decreases the IL-1 level by inhibiting IL-1β mRNA expression to a greater extent than meloxicam administration.展开更多
Grain kernel discoloration(KD)in cereal crops leads to down-grading grain quality and substantial economic losses worldwide.Breeding KD tolerant varieties requires a clear understanding of the genetic basis underlying...Grain kernel discoloration(KD)in cereal crops leads to down-grading grain quality and substantial economic losses worldwide.Breeding KD tolerant varieties requires a clear understanding of the genetic basis underlying this trait.Here,we generated a high-density single nucleotide polymorphisms(SNPs)map for a diverse barley germplasm and collected trait data from two independent field trials for five KD related traits:grain brightness(TL),redness(Ta),yellowness(Tb),black point impact(Tbpi),and total black point in percentage(Tbpt).Although grain brightness and black point is genetically correlated,the grain brightness traits(TL,Ta,and Tb)have significantly higher heritability than that of the black point traits(Tbpt and Tbpi),suggesting black point traits may be more susceptible to environmental influence.Using genome-wide association studies(GWAS),we identified a total of 37 quantitative trait loci(QTL),including two major QTL hotspots on chromosomes 4H and 7H,respectively.The two QTL hotspots are associated with all five KD traits.Further genetic linkage and gene transcription analyses identified candidate genes for the grain KD,including several genes in the flavonoid pathway and plant peroxidase.Our study provides valuable insights into the genetic basis for the grain KD in barley and would greatly facilitate future breeding programs for improving grain KD resistance.展开更多
In recent years, the authors have treated 30 cases of acute lumbar sprain by acupuncture combined with point medicinal injection at Tianzhu (BL 10), and obtained quite good therapeutic results, as is reported in the f...In recent years, the authors have treated 30 cases of acute lumbar sprain by acupuncture combined with point medicinal injection at Tianzhu (BL 10), and obtained quite good therapeutic results, as is reported in the following.展开更多
Single cell trapping in vitro by microfluidic device is an emerging approach for the study of the relationship between single cells and their dynamic biochemical microenvironments. In this paper, a hydrodynamic-based ...Single cell trapping in vitro by microfluidic device is an emerging approach for the study of the relationship between single cells and their dynamic biochemical microenvironments. In this paper, a hydrodynamic-based microfluidic device for single cell trapping is designed using a combination of stagnation point flow and physical barrier.The microfluidic device overcomes the weakness of the traditional ones, which have been only based upon either stagnation point flows or physical barriers, and can conveniently load dynamic biochemical signals to the trapped cell. In addition, it can connect with a programmable syringe pump and a microscope to constitute an integrated experimental system.It is experimentally verified that the microfluidic system can trap single cells in vitro even under flow disturbance and conveniently load biochemical signals to the trapped cell. The designed micro-device would provide a simple yet effective experimental platform for further study of the interactions between single cells and their microenvironments.展开更多
Recently, there have been some attempts of Transformer in 3D point cloud classification. In order to reduce computations, most existing methods focus on local spatial attention,but ignore their content and fail to est...Recently, there have been some attempts of Transformer in 3D point cloud classification. In order to reduce computations, most existing methods focus on local spatial attention,but ignore their content and fail to establish relationships between distant but relevant points. To overcome the limitation of local spatial attention, we propose a point content-based Transformer architecture, called PointConT for short. It exploits the locality of points in the feature space(content-based), which clusters the sampled points with similar features into the same class and computes the self-attention within each class, thus enabling an effective trade-off between capturing long-range dependencies and computational complexity. We further introduce an inception feature aggregator for point cloud classification, which uses parallel structures to aggregate high-frequency and low-frequency information in each branch separately. Extensive experiments show that our PointConT model achieves a remarkable performance on point cloud shape classification. Especially, our method exhibits 90.3% Top-1 accuracy on the hardest setting of ScanObjectN N. Source code of this paper is available at https://github.com/yahuiliu99/PointC onT.展开更多
The material point method(MPM)has been gaining increasing popularity as an appropriate approach to the solution of coupled hydro-mechanical problems involving large deformation.In this paper,we survey the current stat...The material point method(MPM)has been gaining increasing popularity as an appropriate approach to the solution of coupled hydro-mechanical problems involving large deformation.In this paper,we survey the current state-of-the-art in the MPM simulation of hydro-mechanical behaviour in two-phase porous geomaterials.The review covers the recent advances and developments in the MPM and their extensions to capture the coupled hydro-mechanical problems involving large deformations.The focus of this review is aiming at providing a clear picture of what has or has not been developed or implemented for simulating two-phase coupled large deformation problems,which will provide some direct reference for both practitioners and researchers.展开更多
Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of navigation.In the Arctic,merchant ships with low ...Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of navigation.In the Arctic,merchant ships with low ice class often navigate in channels opened up by icebreakers.Navigation in the ice channel often depends on good maneuverability skills and abundant experience from the captain to a large extent.The ship may get stuck if steered into ice fields off the channel.Under this circumstance,it is very important to study how to identify the boundary lines of ice channels with a reliable method.In this paper,a two-staged ice channel identification method is developed based on image segmentation and corner point regression.The first stage employs the image segmentation method to extract channel regions.In the second stage,an intelligent corner regression network is proposed to extract the channel boundary lines from the channel region.A non-intelligent angle-based filtering and clustering method is proposed and compared with corner point regression network.The training and evaluation of the segmentation method and corner regression network are carried out on the synthetic and real ice channel dataset.The evaluation results show that the accuracy of the method using the corner point regression network in the second stage is achieved as high as 73.33%on the synthetic ice channel dataset and 70.66%on the real ice channel dataset,and the processing speed can reach up to 14.58frames per second.展开更多
A new algorithm called homotopy iteration method based on the homotopy function is studied and improved. By the improved homotopy iteration method, Polynomial systems with high Order and deficient can be solved fast a...A new algorithm called homotopy iteration method based on the homotopy function is studied and improved. By the improved homotopy iteration method, Polynomial systems with high Order and deficient can be solved fast and efficiently comparing to the original homotopy iteration method. Numerical examples for the ninepoint path synthesis of four-bar linkages show the advantages and efficiency of the improved homotopy iteration method.展开更多
32 cases of the third lumbar transverse process syndrome were treated mainly byelectroacupuncture at Huatuojiaji points of the first and second lumbar vertebrae, andanother 30 cases of the syndrome by conventional acu...32 cases of the third lumbar transverse process syndrome were treated mainly byelectroacupuncture at Huatuojiaji points of the first and second lumbar vertebrae, andanother 30 cases of the syndrome by conventional acupuncture as the controls. The resultsshowed that treatment by electroacupuncture at Huatuojiaji points was superior inanalgesic effect and clinical total effective rate to that by conventional acupuncture. It isconsidered that the mechanism of treatment by electroacupuncture at Huatuojiaji pointsis related to the trunk of posterior ramus of the spinal nerve where the points are located.展开更多
Cultural relics line graphic serves as a crucial form of traditional artifact information documentation,which is a simple and intuitive product with low cost of displaying compared with 3D models.Dimensionality reduct...Cultural relics line graphic serves as a crucial form of traditional artifact information documentation,which is a simple and intuitive product with low cost of displaying compared with 3D models.Dimensionality reduction is undoubtedly necessary for line drawings.However,most existing methods for artifact drawing rely on the principles of orthographic projection that always cannot avoid angle occlusion and data overlapping while the surface of cultural relics is complex.Therefore,conformal mapping was introduced as a dimensionality reduction way to compensate for the limitation of orthographic projection.Based on the given criteria for assessing surface complexity,this paper proposed a three-dimensional feature guideline extraction method for complex cultural relic surfaces.A 2D and 3D combined factor that measured the importance of points on describing surface features,vertex weight,was designed.Then the selection threshold for feature guideline extraction was determined based on the differences between vertex weight and shape index distributions.The feasibility and stability were verified through experiments conducted on real cultural relic surface data.Results demonstrated the ability of the method to address the challenges associated with the automatic generation of line drawings for complex surfaces.The extraction method and the obtained results will be useful for line graphic drawing,displaying and propaganda of cultural relics.展开更多
By means of programs GTMPAC based- on generalized triangle method,analysis and synthesis of mechanism design in accordance with absolutely graphicalmethod( absolutely germetrical method) are developed.In this paper,we...By means of programs GTMPAC based- on generalized triangle method,analysis and synthesis of mechanism design in accordance with absolutely graphicalmethod( absolutely germetrical method) are developed.In this paper,we make aspecial study about centering- point curve and circling- point curve and couplercurves based on Ball’s points.展开更多
Since 1996,the author has treated 40 cases of protrusion of lumbar intervertebral disc with ultra short wave and the point injection,and obtained good therapeutic effects.This is reported as follows.
According to the World Health Organization, approximately 3 million deaths are prevented each year in the world thanks to vaccination and then, in addition, each year, it makes it possible to avoid nearly 750,000 chil...According to the World Health Organization, approximately 3 million deaths are prevented each year in the world thanks to vaccination and then, in addition, each year, it makes it possible to avoid nearly 750,000 children suffering from serious physical, mental or neurological handicaps and 1.5 million other deaths could be avoided if the vaccination coverage is improved. However, vaccination coverage is often not achieved due to various difficulties encountered by health providers in the expanded program on vaccination activities. Yet, it is important to strengthen the program. This research paper aimed to assess health providers’ points of view on the impact of the project to strengthen the routine expanded program on vaccination in the Barumbu health zone in Kinshasa, Democratic Republic of Congo (RDC). To do so, we surveyed a convenience sample of 234 health providers involved in the implementation of the project, including 210 community relays, 9 permanent nurses, 9 health committee chairpersons and 6 health authorities. A questionnaire related to the objective of the research was submitted to them. After analyzing the data, we found that the points of view of health providers are negative. The performance of the vaccination program was not great. Several reasons were given for this, including the non-involvement of the political and administrative authorities, the failure to respect the funds disbursement circuit and the non-effective financing of vaccination activities in the Barumbu health zone in Kinshasa, DRC.展开更多
The paper discusses the characteristics of next generation services, and analyzes its development barriers and cut-in points.Broadband services that NGN offers have to transit from an unknown state to an popular state...The paper discusses the characteristics of next generation services, and analyzes its development barriers and cut-in points.Broadband services that NGN offers have to transit from an unknown state to an popular state to become a scale economy.Personal information and communication services and multimedia entertainment services will be the cut-in points.展开更多
文摘Point bars are well developed on the Yellow River delta, an~ which theShengli I point bar is the most typical. The point bar, being about 4 km in length and several tensto more than 100 meters in width, is located on the south side of the Shengli Bridge in KenliCounty, Dongying, Shandong. It is a typical fine-grained point bar with silt, which is predominant,some clay and minor plant debris and clay boulders. The Shengli I Point bar has complicated 3-Dstructures. Firstly, in a plane view, it comprises mainly eight sedimentary units, bar edge, baredge, bar platform, bar plain, bar channel, bar gully, bar pond and bar bay, developing side by sideand superimposed one by one m a complex way. Secondly, its vertical structures are very complex dueto the partial superimposition of the 8 sedimentary units. Besides hydatogenesis, very intensivewind erosion, eolian, ice and meltwater actions are also visible on the Shengli I point bar. Thecomplex form is made even more complicated because of the above co-actions.
基金Supported by Project of Fine Reservoir Description Technology of Heavy Oil Reservoir(No.1507)
文摘In order to solve dynamic Problems caused by the internal structure of fluvial reservoir,it is necessa-ry to study the fine anatomy of Point bar. Taking Minghuazhen Formation in the northern block of Q oilfield, Bohai Sea as an examPle,the authors studied identification marks,distribution Pattern and scale of Point bar based on coring,logging and dynamic data. The results show that the length of Point bar and the width of lateral accretion body are 713-911 m and 71-111m,resPectively;the diP angle and the thickness of lateral accretion bedding are 3. 5o-5. 9o and 0. 1-0. 5 m. The lateral accretion beddings are the key factor affecting the seePage velocity of the tracer.
基金Key Program of National Natural Science Foundation of China,No.U2040219National Natural Science Foundation of China,No.51579015Program of National Key Research and Development Plan of China,No.2016YFC0402108, No.2016YFC0402103。
文摘Geomorphic dynamics of alluvial rivers in response to upstream damming have substantial impacts on navigation, habitat protection, and channel stability. The purpose of this study was to determine how flow and sediment regimes, and meander characteristics affect the morphological adjustment of bends in the Lower Jingjiang Reach(LJR) before and after the Three Gorges Project(TGP). Based on detailed field measurements and hydrological and topographic datasets from 1991 to 2016, banks and point bars morphodynamics of 12continuous bends in the LJR were comprehensively analyzed. Point bars in the LJR mainly experienced a net deposition before the TGP operation, but substantially deteriorated with a net erosion rate of 4.6 million m^(3) yr^(-1) in the post-TGP periods(2003–2016), and erosion on heads and upstream margins of point bars was a general adjustment pattern in the 12 bends.The most significant morphological changes of point bars and banks occurred in 2006–2011,indicating a delayed response of the channel evolution of the LJR to damming. Detailed observations suggested that the medium discharges(16,000–18,000 m^(3) s^(-1)) were the most contributive discharges in shaping the morphology of point bars and banks in the LJR after damming. In addition, we revealed the importance of sediment supply on meander deformation of the LJR, driven by sediment exchange over point bars, and more upstream planform deformation tended to occur in bends with high sinuosity(>2.0) in the LJR after damming.The relationship between meander deformation and sinuosity was manifested through the geometric adjustment range of point bars. The morphological adjustments of point bars in the highly curved or compound bends of the LJR were more conducive to cause flow deflections,leading to form concave-bank bars after the TGP operation.
文摘Precipitation samples collected at Point Barrow, Alaska in the August and September of 1994 was analyzed for pH, conductivity and all major ions. A mean pH value of 5.53 was gained, and the samples' conductivity showed no linear correlation with its acidity, which did not agree to the similar work results on the Qinghai Tibet Plateau. Cl - and Na + were found to originate mainly with seasalt. The concentrations of SO 2- 4 varied from event to event. But the exSO 2- 4 concentrations remained small, which indicated less anthropogenic effect on the environment at the site.
文摘BACKGROUND:It has been shown that interleukin-1 (IL-1) may cause inflammatory reactions, which stimulate the nerve root of patients with lumbar intervertebral disc protrusion and leads to pain. Whether the clinical curative effects of acupuncture in the treatment of lumbar and leg pain are linked to an inhibition of local IL-1 secretion is unknown. OBJECTIVE: To assess the influence of acupuncture on IL-1, this study was designed to verify the effects of acupuncture at the "Huatuojiaji (Extra)" point on the nerve root in a rat model of lumbar nerve root compression, compared with administration of meloxicam, a non-steroidal anti-inflammatory drug. DESIGN, TIME AND SETTING: Randomized, controlled, molecular biology experiment, performed at the Experimental Center, Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University between September 2005 and April 2006. MATERIALS: Forty healthy adult Sprague Dawley rats of either gender were included in this study. The rats were randomly and evenly divided into the following four groups: normal control, model, acupuncture and meloxicam groups. Lumbar nerve root compression was induced in rats in the model, acupuncture, and meloxicam groups by inserting a specially made silicon rubber slice at the juncture of the L5 nerve root and the dural sac. The acupuncture needle (pattern number N3030, 30#, 1.5 inch) was purchased from Suzhou Medical Appliance Factory, China. IL-1 enzyme linked immunosorbent assay (ELISA) kit was purchased from Santa Cruz Biotechnology, Inc., USA. METHODS: The acupuncture group was acupunctured at the "Huatuojiaji" point, which is lateral to the compressed L5-6 nerve root, with an acupuncture depth of 0.5 cm. There were two treatment courses, each of involved seven 20-minute acupuncture sessions, one session a day. The meloxicam group was administered intragastrically 3.75 mg/kg meloxicam (5 mg meloxicam /10 mL physiological saline). Rats in the normal control group and model group received an intragastric administration of 10 mL/kg physiological saline. All administrations were performed once a day. MAIN OUTCOME MEASURES: At day 14 post-surgery, the IL-1 level in the compressed nerve root was determined by a streptavidin-peroxidase (S-P) immunohistochemical method, and IL-1β mRNA expression in the compressed nerve root was simultaneously detected by real-time reverse transcription-polymerase chain reaction. RESULTS: The expression levels of IL-1 and IL-1β mRNA in the L5 nerve root were significantly higher in the model group than in the control group (P 〈 0.01). However, the expression levels of IL-1 and IL-1β mRNA were significantly lower in the acupuncture and meloxicam groups than in the model group (P 〈 0.05–0.01). Expression levels of IL-1 and IL-1β mRNA were significantly higher in the acupuncture group than in the meloxicam group (P 〈 0.01). CONCLUSION: Acupuncture at the "Huatuojiaji" point decreases the IL-1 level by inhibiting IL-1β mRNA expression to a greater extent than meloxicam administration.
基金supported by the Australian Grain Research and Development Corporation(UMU00047)。
文摘Grain kernel discoloration(KD)in cereal crops leads to down-grading grain quality and substantial economic losses worldwide.Breeding KD tolerant varieties requires a clear understanding of the genetic basis underlying this trait.Here,we generated a high-density single nucleotide polymorphisms(SNPs)map for a diverse barley germplasm and collected trait data from two independent field trials for five KD related traits:grain brightness(TL),redness(Ta),yellowness(Tb),black point impact(Tbpi),and total black point in percentage(Tbpt).Although grain brightness and black point is genetically correlated,the grain brightness traits(TL,Ta,and Tb)have significantly higher heritability than that of the black point traits(Tbpt and Tbpi),suggesting black point traits may be more susceptible to environmental influence.Using genome-wide association studies(GWAS),we identified a total of 37 quantitative trait loci(QTL),including two major QTL hotspots on chromosomes 4H and 7H,respectively.The two QTL hotspots are associated with all five KD traits.Further genetic linkage and gene transcription analyses identified candidate genes for the grain KD,including several genes in the flavonoid pathway and plant peroxidase.Our study provides valuable insights into the genetic basis for the grain KD in barley and would greatly facilitate future breeding programs for improving grain KD resistance.
文摘In recent years, the authors have treated 30 cases of acute lumbar sprain by acupuncture combined with point medicinal injection at Tianzhu (BL 10), and obtained quite good therapeutic results, as is reported in the following.
基金supported by the National Natural Science Foundation of China (Grants 11172060 and 31370948)
文摘Single cell trapping in vitro by microfluidic device is an emerging approach for the study of the relationship between single cells and their dynamic biochemical microenvironments. In this paper, a hydrodynamic-based microfluidic device for single cell trapping is designed using a combination of stagnation point flow and physical barrier.The microfluidic device overcomes the weakness of the traditional ones, which have been only based upon either stagnation point flows or physical barriers, and can conveniently load dynamic biochemical signals to the trapped cell. In addition, it can connect with a programmable syringe pump and a microscope to constitute an integrated experimental system.It is experimentally verified that the microfluidic system can trap single cells in vitro even under flow disturbance and conveniently load biochemical signals to the trapped cell. The designed micro-device would provide a simple yet effective experimental platform for further study of the interactions between single cells and their microenvironments.
基金supported in part by the Nationa Natural Science Foundation of China (61876011)the National Key Research and Development Program of China (2022YFB4703700)+1 种基金the Key Research and Development Program 2020 of Guangzhou (202007050002)the Key-Area Research and Development Program of Guangdong Province (2020B090921003)。
文摘Recently, there have been some attempts of Transformer in 3D point cloud classification. In order to reduce computations, most existing methods focus on local spatial attention,but ignore their content and fail to establish relationships between distant but relevant points. To overcome the limitation of local spatial attention, we propose a point content-based Transformer architecture, called PointConT for short. It exploits the locality of points in the feature space(content-based), which clusters the sampled points with similar features into the same class and computes the self-attention within each class, thus enabling an effective trade-off between capturing long-range dependencies and computational complexity. We further introduce an inception feature aggregator for point cloud classification, which uses parallel structures to aggregate high-frequency and low-frequency information in each branch separately. Extensive experiments show that our PointConT model achieves a remarkable performance on point cloud shape classification. Especially, our method exhibits 90.3% Top-1 accuracy on the hardest setting of ScanObjectN N. Source code of this paper is available at https://github.com/yahuiliu99/PointC onT.
基金The financial supports from National Outstanding Youth Science Fund Project of National Natural Science Foundation of China(Grant No.52022112)the International Postdoctoral Exchange Fellowship Program(Talent-Introduction Program,Grant No.YJ20220219)。
文摘The material point method(MPM)has been gaining increasing popularity as an appropriate approach to the solution of coupled hydro-mechanical problems involving large deformation.In this paper,we survey the current state-of-the-art in the MPM simulation of hydro-mechanical behaviour in two-phase porous geomaterials.The review covers the recent advances and developments in the MPM and their extensions to capture the coupled hydro-mechanical problems involving large deformations.The focus of this review is aiming at providing a clear picture of what has or has not been developed or implemented for simulating two-phase coupled large deformation problems,which will provide some direct reference for both practitioners and researchers.
基金financially supported by the National Key Research and Development Program(Grant No.2022YFE0107000)the General Projects of the National Natural Science Foundation of China(Grant No.52171259)the High-Tech Ship Research Project of the Ministry of Industry and Information Technology(Grant No.[2021]342)。
文摘Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of navigation.In the Arctic,merchant ships with low ice class often navigate in channels opened up by icebreakers.Navigation in the ice channel often depends on good maneuverability skills and abundant experience from the captain to a large extent.The ship may get stuck if steered into ice fields off the channel.Under this circumstance,it is very important to study how to identify the boundary lines of ice channels with a reliable method.In this paper,a two-staged ice channel identification method is developed based on image segmentation and corner point regression.The first stage employs the image segmentation method to extract channel regions.In the second stage,an intelligent corner regression network is proposed to extract the channel boundary lines from the channel region.A non-intelligent angle-based filtering and clustering method is proposed and compared with corner point regression network.The training and evaluation of the segmentation method and corner regression network are carried out on the synthetic and real ice channel dataset.The evaluation results show that the accuracy of the method using the corner point regression network in the second stage is achieved as high as 73.33%on the synthetic ice channel dataset and 70.66%on the real ice channel dataset,and the processing speed can reach up to 14.58frames per second.
文摘A new algorithm called homotopy iteration method based on the homotopy function is studied and improved. By the improved homotopy iteration method, Polynomial systems with high Order and deficient can be solved fast and efficiently comparing to the original homotopy iteration method. Numerical examples for the ninepoint path synthesis of four-bar linkages show the advantages and efficiency of the improved homotopy iteration method.
文摘32 cases of the third lumbar transverse process syndrome were treated mainly byelectroacupuncture at Huatuojiaji points of the first and second lumbar vertebrae, andanother 30 cases of the syndrome by conventional acupuncture as the controls. The resultsshowed that treatment by electroacupuncture at Huatuojiaji points was superior inanalgesic effect and clinical total effective rate to that by conventional acupuncture. It isconsidered that the mechanism of treatment by electroacupuncture at Huatuojiaji pointsis related to the trunk of posterior ramus of the spinal nerve where the points are located.
基金National Natural Science Foundation of China(Nos.42071444,42101444)。
文摘Cultural relics line graphic serves as a crucial form of traditional artifact information documentation,which is a simple and intuitive product with low cost of displaying compared with 3D models.Dimensionality reduction is undoubtedly necessary for line drawings.However,most existing methods for artifact drawing rely on the principles of orthographic projection that always cannot avoid angle occlusion and data overlapping while the surface of cultural relics is complex.Therefore,conformal mapping was introduced as a dimensionality reduction way to compensate for the limitation of orthographic projection.Based on the given criteria for assessing surface complexity,this paper proposed a three-dimensional feature guideline extraction method for complex cultural relic surfaces.A 2D and 3D combined factor that measured the importance of points on describing surface features,vertex weight,was designed.Then the selection threshold for feature guideline extraction was determined based on the differences between vertex weight and shape index distributions.The feasibility and stability were verified through experiments conducted on real cultural relic surface data.Results demonstrated the ability of the method to address the challenges associated with the automatic generation of line drawings for complex surfaces.The extraction method and the obtained results will be useful for line graphic drawing,displaying and propaganda of cultural relics.
文摘By means of programs GTMPAC based- on generalized triangle method,analysis and synthesis of mechanism design in accordance with absolutely graphicalmethod( absolutely germetrical method) are developed.In this paper,we make aspecial study about centering- point curve and circling- point curve and couplercurves based on Ball’s points.
文摘Since 1996,the author has treated 40 cases of protrusion of lumbar intervertebral disc with ultra short wave and the point injection,and obtained good therapeutic effects.This is reported as follows.
文摘According to the World Health Organization, approximately 3 million deaths are prevented each year in the world thanks to vaccination and then, in addition, each year, it makes it possible to avoid nearly 750,000 children suffering from serious physical, mental or neurological handicaps and 1.5 million other deaths could be avoided if the vaccination coverage is improved. However, vaccination coverage is often not achieved due to various difficulties encountered by health providers in the expanded program on vaccination activities. Yet, it is important to strengthen the program. This research paper aimed to assess health providers’ points of view on the impact of the project to strengthen the routine expanded program on vaccination in the Barumbu health zone in Kinshasa, Democratic Republic of Congo (RDC). To do so, we surveyed a convenience sample of 234 health providers involved in the implementation of the project, including 210 community relays, 9 permanent nurses, 9 health committee chairpersons and 6 health authorities. A questionnaire related to the objective of the research was submitted to them. After analyzing the data, we found that the points of view of health providers are negative. The performance of the vaccination program was not great. Several reasons were given for this, including the non-involvement of the political and administrative authorities, the failure to respect the funds disbursement circuit and the non-effective financing of vaccination activities in the Barumbu health zone in Kinshasa, DRC.
文摘The paper discusses the characteristics of next generation services, and analyzes its development barriers and cut-in points.Broadband services that NGN offers have to transit from an unknown state to an popular state to become a scale economy.Personal information and communication services and multimedia entertainment services will be the cut-in points.