This paper reports that the designed optical polarization mode dispersion compensator shows a good performance under the real-time variation of differential group delay, state of polarization and principal state of po...This paper reports that the designed optical polarization mode dispersion compensator shows a good performance under the real-time variation of differential group delay, state of polarization and principal state of polarization in a (40×43)-Gb/s dense-wavelength-multiplexing, 1200-km enhanced return-to-zero differential-quadrature-phase-shift- keying (RZ-DQPSK) system. The polarization mode dispersion tolerance of the system is improved by 26 ps using the optical polarization mode dispersion compensator. The short and long time stabilities are tested with the bit error ratio recorded.展开更多
Polarization mode dispersion(PMD) is considered to be the ultimate limitation in high-speed optical fiber communication systems. Establishing an effective control algorithm for adaptive PMD compensation is a challengi...Polarization mode dispersion(PMD) is considered to be the ultimate limitation in high-speed optical fiber communication systems. Establishing an effective control algorithm for adaptive PMD compensation is a challenging task, because PMD possesses the time-varying and statistical properties. The particle swarm optimization(PSO) algorithm is introduced into self-adaptive PMD compensation as feedback control algorithm. The experiment results show that PSO-based control algorithm has some unique features of rapid convergence to the global optimum without being trapped in local sub-optima and good robustness to noise in the optical fiber transmission line that has never been achieved in PMD compensation before.展开更多
A simple two-section polarization mode dispersion(PMD) compensator is proposed for multichannel PMD compensation, which can compensate two or even more channels simultaneously. Because of the statistical characteristi...A simple two-section polarization mode dispersion(PMD) compensator is proposed for multichannel PMD compensation, which can compensate two or even more channels simultaneously. Because of the statistical characteristics and the frequency-dependence of PMD, for current single mode fiber with moderate PMD, the probability that all channels are severely degraded at the same time is extremely small, which makes it possible to compensate a dense wavelength division multiplexing(DWDM) transmission system with moderate PMD using this compensator. It is shown that the outage probability of a 40×43 Gb/s DWDM transmission system using this compensator is decreased significantly from 3.6×10-3 to 3.6×10-5.展开更多
In this study,the multi-peak terahertz metamaterials sensors are designed and fabricated,whose structures are the asymmetrical single split ring(SSR)and three split rings(TSR).The resonant formation and sensing mechan...In this study,the multi-peak terahertz metamaterials sensors are designed and fabricated,whose structures are the asymmetrical single split ring(SSR)and three split rings(TSR).The resonant formation and sensing mechanism of the two structures are investigated by using the finite-difference time-domain(FDTD)method.Vitamin B6(VB6)and its reactants with bovine serum protein(BSA)are tested as the medium,and the sensing experiments of the SSR and TSR are carried out.The experimental and simulation results indicate the consistent law,which is the sensitivity of the resonance in the transverse magnetic(TM)mode is much greater than that in the transverse electric(TE)mode.According to the weighted average method and the law for unequal precision measuring,the quality factor of the resonance is used as the weighting coefficient to calculate the comprehensive evaluation parameter(CEP)of the multi-peak metamaterials sensors in the TE and TM modes based on the experimental data.When the CEP and frequency shifts are as the evaluation parameter in experiments,the law’s variation of the CEP is consistent with that of the frequency shift,indicating that it is feasible to characterize the sensing characteristics of metamaterials with the CEP,which presents simplified characteristics of multi-peak metamaterials at different polarization modes.The method implies that the different influencing factors may be integrated into the CEP with the idea of weight,which promotes the practical application of the metamaterials sensor.The revelation of the sensing law also provides a method for the design of the terahertz metamaterials sensor with the high sensitivity.展开更多
In this paper, we simulate the effect of Polarization Mode Dispersion( PMD ) on 40 Gb/s dispersion compensation transmission system by resolving the coupled nonlinear Schrodinger equation, and calculate the perf...In this paper, we simulate the effect of Polarization Mode Dispersion( PMD ) on 40 Gb/s dispersion compensation transmission system by resolving the coupled nonlinear Schrodinger equation, and calculate the performance of system with different duty cycle order and chirp of the super Gaussian pulse. The results show that the performance of the system changes with these parameters, and there is a group of optimum parameters for the optimum performance of the system.展开更多
A tunable polarization mode dispersion (PMD) compensator based on strain-ckirped fiber Bragg gratings (FBGs) is proposed. It natures in flexible designing, large tuning range, without using linear or nonlinear chirped...A tunable polarization mode dispersion (PMD) compensator based on strain-ckirped fiber Bragg gratings (FBGs) is proposed. It natures in flexible designing, large tuning range, without using linear or nonlinear chirped phase mask, fast tuning response time, continuously adjustable, all-fiber based, compact, and cheap.展开更多
The probability distribution of the differential group delay for arbitrary mode coupling is simulated with Monte-Carlo method. Fitting the simulation results, we obtain probability distribution function for arbitrary ...The probability distribution of the differential group delay for arbitrary mode coupling is simulated with Monte-Carlo method. Fitting the simulation results, we obtain probability distribution function for arbitrary mode coupling.展开更多
In this paper, the dispersion managed soliton (DMS) transmission equation is built on considering the effects of polarization mode dispersion (PMD) and filter control. The DMS transmission of filtering control in cons...In this paper, the dispersion managed soliton (DMS) transmission equation is built on considering the effects of polarization mode dispersion (PMD) and filter control. The DMS transmission of filtering control in constant birefringence fibers is firstly analyzed by varitional method, from which the evolving rules of characteristical DMS parameters are obtained. Secondly, the stability of DMS transmission and its timing jitter are investigated in the random varying birefringence fibers with the conventional model of PMD. The results reveal that filter control DMS system has powerful robustness to PMD effects and DMS's timing jitter can be decreased considerably with the help of filters.展开更多
We propose a novel transmitter and receiver for differential quadrature phase-shift keying (DQPSK) format. The impact of the first-order polarization mode dispersion (PMD) on systems using DQPSK with 100- Gb/s non...We propose a novel transmitter and receiver for differential quadrature phase-shift keying (DQPSK) format. The impact of the first-order polarization mode dispersion (PMD) on systems using DQPSK with 100- Gb/s non-return-to-zero (NRZ) or return-to-zero (RZ) format is investigated. Through computing the eye openings of DQPSK formats under different PMD conditions, it is found that NRZ DQPSK, as compared with RZ DQPSK, incurs smaller eye opening due to PMD. Carrier-suppressed return-to-zero (CSRZ) DQPSK format has better tolerance than RZ DQPSK format to PMD for a given bit rate.展开更多
This paper presents the sampling and feedback control techniques, which are the kernel of our experiment on adaptive Polarization Mode Dispersion (PMD) compensation for optical fiber communication systems. Some key po...This paper presents the sampling and feedback control techniques, which are the kernel of our experiment on adaptive Polarization Mode Dispersion (PMD) compensation for optical fiber communication systems. Some key points on sampling and feedback techniques are discussed and practical resolutions for them are put forward.展开更多
This paper has designed 2-channel dense wavelength division multiplexing (DWDM) chaotic sys- tem at the frequencies of 193.1 and 193,2THz, respec- tively. The optical chaotic signals were produced by using the semic...This paper has designed 2-channel dense wavelength division multiplexing (DWDM) chaotic sys- tem at the frequencies of 193.1 and 193,2THz, respec- tively. The optical chaotic signals were produced by using the semiconductor laser that is numerically modeled by employing laser rate equations. These two channels were multiplexed and then propagated through single mode optical fiber (SMF) of 80kin length with dispersion compensating fiber of 16 km length. Erbium doped fiber amplifier (EDFA) was used to compensate the power losses in the SMF. In lhis paper, we investigated the effects of polarization mode dispersion (PMD) and nonlinearities especially stimulated Raman scattering (SRS) on 2 channel DWDM chaotic communication system by varying the length of the SMF and value of differential group delay (DGD).展开更多
On-chip optical communications are growingly aiming at multimode operation together with mode-division multiplex-ing to further increase the transmission capacity.Optical switches,which are capable of optical signals ...On-chip optical communications are growingly aiming at multimode operation together with mode-division multiplex-ing to further increase the transmission capacity.Optical switches,which are capable of optical signals switching at the nodes,play a key role in optical networks.We demonstrate a 2×2 electro-optic Mach-Zehnder interferometer-based mode-and polar-ization-selective switch fabricated by standard complementary metal-oxide-semiconductor process.An electro optic tuner based on a PN-doped junction in one of the Mach-Zehnder interferometer arms enables dynamic switching in 11 ns.For all the channels,the overall insertion losses and inter-modal crosstalk values are below 9.03 and-15.86 dB at 1550 nm,respect-ively.展开更多
We design an 850 nm tunable vertical-cavity surface-emitting laser(VCSEL)structure using an internal-cavity sub-wavelength grating.The use of such a tuning structure allows for wider wavelength tuning range and more s...We design an 850 nm tunable vertical-cavity surface-emitting laser(VCSEL)structure using an internal-cavity sub-wavelength grating.The use of such a tuning structure allows for wider wavelength tuning range and more stable single-polarization as compared to conventional tunable VCSELs.The features of the internal-cavity grating effect on the wavelength tuning and polarization characteristics of the tunable VCSEL are analyzed.The simulation results show that the largest wavelength tuning range achieves 44.2 nm,and the maximum orthogonal polarization suppression ratio(OPSR)is 33.4 dB(TE-type)and 38.7 dB(TM-type).展开更多
Although a number of methods are available for evaluating Linezolid and its possible impurities, a common method for separation if its potential impurities, degradants and enantiomer in a single method with good effic...Although a number of methods are available for evaluating Linezolid and its possible impurities, a common method for separation if its potential impurities, degradants and enantiomer in a single method with good efficiency remain unavailable. With the objective of developing an advanced method with shorter runtimes, a simple, precise, accurate stability-indicating LC method was developed for the determination of purity of Linezolid drug substance and drug products in bulk samples and pharmaceutical dosage forms in the presence of its impurities and degradation products. This method is capable of separating all the related substances of Linezolid along with the chiral impurity. This method can also be used for the estimation of assay of Linezolid in drug substance as well as in drug product. The method was developed using Chiralpak IA (250 mm 4.6 mm, 5 mm) column. A mixture of acetonitrile, ethanol, n-butyl amine and trifluoro acetic acid in 96:4:0.10:0.16 (v/v/v/v) ratio was used as a mobile phase. The eluted compounds were monitored at 254 nm. Linezolid was subjected to the stress conditions of oxidative, acid, base, hydrolytic, thermal and photolytic degradation. The degradation products were well resolved from main peak and its impurities, proving the stability-indicating power of the method. The developed method was validated as per International Conference on Harmonization (ICH) guidelines with respect to specificity, limit of detection, limit of quantification, precision, linearity, accuracy, robustness and system suitability.展开更多
Previous studies revealed that the error of pole coordinate prediction will significantly increase for a prediction period longer than 100 days, and this is mainly caused by short period oscillations. Empirical mode d...Previous studies revealed that the error of pole coordinate prediction will significantly increase for a prediction period longer than 100 days, and this is mainly caused by short period oscillations. Empirical mode decomposition (EMD), which is increasingly popular and has advantages over classical wavelet decomposition, can be used to remove short period variations from observed time series of pole co- ordinates. A hybrid model combing EMD and extreme learning machine (ELM), where high frequency signals are removed and processed time series is then modeled and predicted, is summarized in this paper. The prediction performance of the hybrid model is compared with that of the ELM-only method created from original time series. The results show that the proposed hybrid model outperforms the pure ELM method for both short-term and long-term prediction of pole coordinates. The improvement of prediction accuracy up to 360 days in the future is found to be 24.91% and 26.79% on average in terms of mean absolute error (MAE) for the xp and yp components of pole coordinates, respectively.展开更多
This paper puts forward a novel magnetically insulated transmission line oscillator (MILO) for the first time which takes a modified HEM11 mode as its main interaction mode. The excitation of the oscillation mode is...This paper puts forward a novel magnetically insulated transmission line oscillator (MILO) for the first time which takes a modified HEM11 mode as its main interaction mode. The excitation of the oscillation mode is made possible by carefully adjusting the arrangements of each resonant cavity in a two-dimensional (2-D) slow wave structure. The high frequency characteristics are analyzed and a PIC simulation is carried out; the detailed results are discussed to get a better understanding of this new MILO. Employing an electron beam of about 441 kV and 39.7 kA, it finds that the modified HEM11 mode MILO generates a high power microwave output of about 1.47 GW at 1.45 GHz. The power conversion efficiency is about 8.4% and the generated microwave is in a TEll-like circularly polarized mode; its polarization direction is decided by the rotation direction of the SWS.展开更多
Longitudinal polar modes generate a macroscopic electric field in piezoelectric crystals and cause an additional mechanism of Raman scattering. The classical theory holds that transverse polar modes cannot produce suc...Longitudinal polar modes generate a macroscopic electric field in piezoelectric crystals and cause an additional mechanism of Raman scattering. The classical theory holds that transverse polar modes cannot produce such an additional mechanism. Our quantum theory shows that there is an additional Raman scattering mechanism arising from the electro-optic effect of transverse polar modes.展开更多
Lanthanide-based microlasers have attracted considerable attention owing to their large anti-Stokes shifts,multiple emission bands,and narrow linewidths.Various applications of microlasers,such as optical communicatio...Lanthanide-based microlasers have attracted considerable attention owing to their large anti-Stokes shifts,multiple emission bands,and narrow linewidths.Various applications of microlasers,such as optical communication,optical storage,and polarization imaging,require selecting the appropriate laser polarization mode and remote control of the laser properties.Here,we propose a unique plasmon-assisted method for the mode selection and remote control of microlasing using a lanthanide-based microcavity coupled with surface plasmon polaritons(SPPs)that propagate on a silver microplate.With this method,the transverse electrical(TE)mode of microlasers can be easily separated from the transverse magnetic(TM)mode.Because the SPPs excited on the silver microplate only support TM mode propagation,the reserved TE mode is resonance-enhanced in the microcavity and amplified by the local electromagnetic field.Meanwhile,lasingmode splitting can be observed under the near-field excitation of SPPs due to the coherent coupling between the microcavity and mirror microcavity modes.Benefiting from the long-distance propagation characteristics of tens of micrometers of SPPs on a silver microplate,remote excitation and control of upconversion microlasing can also be realized.These plasmon-assisted polarization mode-optional and remote-controllable upconversion microlasers have promising prospects in on-chip optoelectronic devices,encrypted optical information transmission,and high-precision sensors.展开更多
We demonstrate the transmission of a microwave frequency signal at 10 GHz over a 112-km urban fiber link based on a novel simple-architecture electronic phase compensation system.The key element of the system is the l...We demonstrate the transmission of a microwave frequency signal at 10 GHz over a 112-km urban fiber link based on a novel simple-architecture electronic phase compensation system.The key element of the system is the low noise frequency divider by 4 to differentiate the frequency of the forward signal from that of the backward one,thus suppressing the effect of Brillouin backscattering and parasitic reflection along the link.In terms of overlapping Allan deviation,the frequency transfer instability of 4.2×10-15 at 1-s integration time and 1.6×10-18 at one-day integration time was achieved.In addition,its sensitivity to the polarization mode dispersion in fiber is analyzed by comparing the results with and without laser polarization scrambling.Generally,with simplicity and robustness,the system can offer great potentials in constructing cascaded frequency transfer system and facilitate the building of fiber-based microwave transfer network.展开更多
Based on uniform fiber Bragg grating bonded with a magnetostrictive rod in the non-uniform magnetic field,a novel PMD compensation technique is proposed.This all-fiber PMD compensation technology is cost-effective and...Based on uniform fiber Bragg grating bonded with a magnetostrictive rod in the non-uniform magnetic field,a novel PMD compensation technique is proposed.This all-fiber PMD compensation technology is cost-effective and flexible in designing the differential group delay profile.展开更多
基金Project supported by the Huawei Technology Project (Grant No.YBON2008014)the National "863" High Technology Projects (Grant No.2009AA01Z224)
文摘This paper reports that the designed optical polarization mode dispersion compensator shows a good performance under the real-time variation of differential group delay, state of polarization and principal state of polarization in a (40×43)-Gb/s dense-wavelength-multiplexing, 1200-km enhanced return-to-zero differential-quadrature-phase-shift- keying (RZ-DQPSK) system. The polarization mode dispersion tolerance of the system is improved by 26 ps using the optical polarization mode dispersion compensator. The short and long time stabilities are tested with the bit error ratio recorded.
基金National Natural Science Foundation of China(60577046) Cooperation Building Project of Beijing EducationCommittee(XK100130437)
文摘Polarization mode dispersion(PMD) is considered to be the ultimate limitation in high-speed optical fiber communication systems. Establishing an effective control algorithm for adaptive PMD compensation is a challenging task, because PMD possesses the time-varying and statistical properties. The particle swarm optimization(PSO) algorithm is introduced into self-adaptive PMD compensation as feedback control algorithm. The experiment results show that PSO-based control algorithm has some unique features of rapid convergence to the global optimum without being trapped in local sub-optima and good robustness to noise in the optical fiber transmission line that has never been achieved in PMD compensation before.
基金National Nature Science Foundation of China(60320130174)
文摘A simple two-section polarization mode dispersion(PMD) compensator is proposed for multichannel PMD compensation, which can compensate two or even more channels simultaneously. Because of the statistical characteristics and the frequency-dependence of PMD, for current single mode fiber with moderate PMD, the probability that all channels are severely degraded at the same time is extremely small, which makes it possible to compensate a dense wavelength division multiplexing(DWDM) transmission system with moderate PMD using this compensator. It is shown that the outage probability of a 40×43 Gb/s DWDM transmission system using this compensator is decreased significantly from 3.6×10-3 to 3.6×10-5.
基金The authors are grateful for the financial support from the National Natural Science Foundation of China(NSFC)(Grant Nos.62065005 and 62063003)the Natural Science Foundation of Guangxi(Grant Nos.2021GXNSFBA196081 and 2021AC19093)the Foundation from Guangxi Key Laboratory of Automatic Detection Technology and Instrument(Grant Nos.YQ20116,YQ21109,and YQ19103).
文摘In this study,the multi-peak terahertz metamaterials sensors are designed and fabricated,whose structures are the asymmetrical single split ring(SSR)and three split rings(TSR).The resonant formation and sensing mechanism of the two structures are investigated by using the finite-difference time-domain(FDTD)method.Vitamin B6(VB6)and its reactants with bovine serum protein(BSA)are tested as the medium,and the sensing experiments of the SSR and TSR are carried out.The experimental and simulation results indicate the consistent law,which is the sensitivity of the resonance in the transverse magnetic(TM)mode is much greater than that in the transverse electric(TE)mode.According to the weighted average method and the law for unequal precision measuring,the quality factor of the resonance is used as the weighting coefficient to calculate the comprehensive evaluation parameter(CEP)of the multi-peak metamaterials sensors in the TE and TM modes based on the experimental data.When the CEP and frequency shifts are as the evaluation parameter in experiments,the law’s variation of the CEP is consistent with that of the frequency shift,indicating that it is feasible to characterize the sensing characteristics of metamaterials with the CEP,which presents simplified characteristics of multi-peak metamaterials at different polarization modes.The method implies that the different influencing factors may be integrated into the CEP with the idea of weight,which promotes the practical application of the metamaterials sensor.The revelation of the sensing law also provides a method for the design of the terahertz metamaterials sensor with the high sensitivity.
文摘In this paper, we simulate the effect of Polarization Mode Dispersion( PMD ) on 40 Gb/s dispersion compensation transmission system by resolving the coupled nonlinear Schrodinger equation, and calculate the performance of system with different duty cycle order and chirp of the super Gaussian pulse. The results show that the performance of the system changes with these parameters, and there is a group of optimum parameters for the optimum performance of the system.
基金This work was supported by the National 973 Basic Research and Development Program of China (No. 2003CB314901), the National Natural Science Foundation of China (No. 60377026), the National "863" High Technology Project of China (No. 2003AA311070),
文摘A tunable polarization mode dispersion (PMD) compensator based on strain-ckirped fiber Bragg gratings (FBGs) is proposed. It natures in flexible designing, large tuning range, without using linear or nonlinear chirped phase mask, fast tuning response time, continuously adjustable, all-fiber based, compact, and cheap.
文摘The probability distribution of the differential group delay for arbitrary mode coupling is simulated with Monte-Carlo method. Fitting the simulation results, we obtain probability distribution function for arbitrary mode coupling.
基金This work was supported by the National Natural Science Foundation under Grant No.69982006 and 60132040.
文摘In this paper, the dispersion managed soliton (DMS) transmission equation is built on considering the effects of polarization mode dispersion (PMD) and filter control. The DMS transmission of filtering control in constant birefringence fibers is firstly analyzed by varitional method, from which the evolving rules of characteristical DMS parameters are obtained. Secondly, the stability of DMS transmission and its timing jitter are investigated in the random varying birefringence fibers with the conventional model of PMD. The results reveal that filter control DMS system has powerful robustness to PMD effects and DMS's timing jitter can be decreased considerably with the help of filters.
基金supported by the National"863"Program of China(No.2007AA01Z263)the Hunan Provincial Natural Science Foundation of China(No.06JJ50108)+1 种基金the Open Fund of Key Laboratory of Optical Communication and Lightwave Technologies(Beijing University of Posts Telecommunications,Ministry of Education,P.R.China)the Program for New Century Excellent Talents in University,and the Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20040532005).
文摘We propose a novel transmitter and receiver for differential quadrature phase-shift keying (DQPSK) format. The impact of the first-order polarization mode dispersion (PMD) on systems using DQPSK with 100- Gb/s non-return-to-zero (NRZ) or return-to-zero (RZ) format is investigated. Through computing the eye openings of DQPSK formats under different PMD conditions, it is found that NRZ DQPSK, as compared with RZ DQPSK, incurs smaller eye opening due to PMD. Carrier-suppressed return-to-zero (CSRZ) DQPSK format has better tolerance than RZ DQPSK format to PMD for a given bit rate.
文摘This paper presents the sampling and feedback control techniques, which are the kernel of our experiment on adaptive Polarization Mode Dispersion (PMD) compensation for optical fiber communication systems. Some key points on sampling and feedback techniques are discussed and practical resolutions for them are put forward.
文摘This paper has designed 2-channel dense wavelength division multiplexing (DWDM) chaotic sys- tem at the frequencies of 193.1 and 193,2THz, respec- tively. The optical chaotic signals were produced by using the semiconductor laser that is numerically modeled by employing laser rate equations. These two channels were multiplexed and then propagated through single mode optical fiber (SMF) of 80kin length with dispersion compensating fiber of 16 km length. Erbium doped fiber amplifier (EDFA) was used to compensate the power losses in the SMF. In lhis paper, we investigated the effects of polarization mode dispersion (PMD) and nonlinearities especially stimulated Raman scattering (SRS) on 2 channel DWDM chaotic communication system by varying the length of the SMF and value of differential group delay (DGD).
基金supported in part by the National Key Research and Development Program of China under Grant 2019YFB2203600the National Natural Science Foundation of China(NSFC)under Grant 61975115/61835008/62035016the Science and Technology Commission of Shanghai Municipality under Grant 2017SHZDZX03。
文摘On-chip optical communications are growingly aiming at multimode operation together with mode-division multiplex-ing to further increase the transmission capacity.Optical switches,which are capable of optical signals switching at the nodes,play a key role in optical networks.We demonstrate a 2×2 electro-optic Mach-Zehnder interferometer-based mode-and polar-ization-selective switch fabricated by standard complementary metal-oxide-semiconductor process.An electro optic tuner based on a PN-doped junction in one of the Mach-Zehnder interferometer arms enables dynamic switching in 11 ns.For all the channels,the overall insertion losses and inter-modal crosstalk values are below 9.03 and-15.86 dB at 1550 nm,respect-ively.
基金the Jilin Science and Technology Development Plan,China(Grant Nos.20180519018JH and 20190302052GX)Jilin Education Department“135”Science and Technology,China(Grant No.JJKH20190543KJ)+1 种基金the National Natural Science Foundation of China(Grant No.11474038)the Key Project of Equipment Pre-Research Fund of China(Grant No.61404140103)。
文摘We design an 850 nm tunable vertical-cavity surface-emitting laser(VCSEL)structure using an internal-cavity sub-wavelength grating.The use of such a tuning structure allows for wider wavelength tuning range and more stable single-polarization as compared to conventional tunable VCSELs.The features of the internal-cavity grating effect on the wavelength tuning and polarization characteristics of the tunable VCSEL are analyzed.The simulation results show that the largest wavelength tuning range achieves 44.2 nm,and the maximum orthogonal polarization suppression ratio(OPSR)is 33.4 dB(TE-type)and 38.7 dB(TM-type).
文摘Although a number of methods are available for evaluating Linezolid and its possible impurities, a common method for separation if its potential impurities, degradants and enantiomer in a single method with good efficiency remain unavailable. With the objective of developing an advanced method with shorter runtimes, a simple, precise, accurate stability-indicating LC method was developed for the determination of purity of Linezolid drug substance and drug products in bulk samples and pharmaceutical dosage forms in the presence of its impurities and degradation products. This method is capable of separating all the related substances of Linezolid along with the chiral impurity. This method can also be used for the estimation of assay of Linezolid in drug substance as well as in drug product. The method was developed using Chiralpak IA (250 mm 4.6 mm, 5 mm) column. A mixture of acetonitrile, ethanol, n-butyl amine and trifluoro acetic acid in 96:4:0.10:0.16 (v/v/v/v) ratio was used as a mobile phase. The eluted compounds were monitored at 254 nm. Linezolid was subjected to the stress conditions of oxidative, acid, base, hydrolytic, thermal and photolytic degradation. The degradation products were well resolved from main peak and its impurities, proving the stability-indicating power of the method. The developed method was validated as per International Conference on Harmonization (ICH) guidelines with respect to specificity, limit of detection, limit of quantification, precision, linearity, accuracy, robustness and system suitability.
基金supported by Chinese Academy of Sciences(No.201491)“Light of West China” Program(201491)
文摘Previous studies revealed that the error of pole coordinate prediction will significantly increase for a prediction period longer than 100 days, and this is mainly caused by short period oscillations. Empirical mode decomposition (EMD), which is increasingly popular and has advantages over classical wavelet decomposition, can be used to remove short period variations from observed time series of pole co- ordinates. A hybrid model combing EMD and extreme learning machine (ELM), where high frequency signals are removed and processed time series is then modeled and predicted, is summarized in this paper. The prediction performance of the hybrid model is compared with that of the ELM-only method created from original time series. The results show that the proposed hybrid model outperforms the pure ELM method for both short-term and long-term prediction of pole coordinates. The improvement of prediction accuracy up to 360 days in the future is found to be 24.91% and 26.79% on average in terms of mean absolute error (MAE) for the xp and yp components of pole coordinates, respectively.
基金Project supported by the Science Foundation of the China Academy of Engineering Physics (Grant No 2008B0402046)
文摘This paper puts forward a novel magnetically insulated transmission line oscillator (MILO) for the first time which takes a modified HEM11 mode as its main interaction mode. The excitation of the oscillation mode is made possible by carefully adjusting the arrangements of each resonant cavity in a two-dimensional (2-D) slow wave structure. The high frequency characteristics are analyzed and a PIC simulation is carried out; the detailed results are discussed to get a better understanding of this new MILO. Employing an electron beam of about 441 kV and 39.7 kA, it finds that the modified HEM11 mode MILO generates a high power microwave output of about 1.47 GW at 1.45 GHz. The power conversion efficiency is about 8.4% and the generated microwave is in a TEll-like circularly polarized mode; its polarization direction is decided by the rotation direction of the SWS.
文摘Longitudinal polar modes generate a macroscopic electric field in piezoelectric crystals and cause an additional mechanism of Raman scattering. The classical theory holds that transverse polar modes cannot produce such an additional mechanism. Our quantum theory shows that there is an additional Raman scattering mechanism arising from the electro-optic effect of transverse polar modes.
基金supported by the National Natural Science Foundation of China(Grant Nos.U22A6005,92150110,12074237,and 12304426)the National Key R&D Program of China(Grant Nos.2020YFA0211300 and 2021YFA1201500)+3 种基金the Natural Science Foundation of Shaanxi Province(Grant No.2024JC-JCQN-07)the Fundamental Science Foundation of Shaanxi(Grant No.22JSZ010)the Fundamental Research Funds for Central Universities(Grant Nos.GK202201012,GK202308001,and LHRCTS23065)the Xi’an Young Elite Scientists Sponsorship Program(Grant No.1203050367)
文摘Lanthanide-based microlasers have attracted considerable attention owing to their large anti-Stokes shifts,multiple emission bands,and narrow linewidths.Various applications of microlasers,such as optical communication,optical storage,and polarization imaging,require selecting the appropriate laser polarization mode and remote control of the laser properties.Here,we propose a unique plasmon-assisted method for the mode selection and remote control of microlasing using a lanthanide-based microcavity coupled with surface plasmon polaritons(SPPs)that propagate on a silver microplate.With this method,the transverse electrical(TE)mode of microlasers can be easily separated from the transverse magnetic(TM)mode.Because the SPPs excited on the silver microplate only support TM mode propagation,the reserved TE mode is resonance-enhanced in the microcavity and amplified by the local electromagnetic field.Meanwhile,lasingmode splitting can be observed under the near-field excitation of SPPs due to the coherent coupling between the microcavity and mirror microcavity modes.Benefiting from the long-distance propagation characteristics of tens of micrometers of SPPs on a silver microplate,remote excitation and control of upconversion microlasing can also be realized.These plasmon-assisted polarization mode-optional and remote-controllable upconversion microlasers have promising prospects in on-chip optoelectronic devices,encrypted optical information transmission,and high-precision sensors.
基金National Natural Science Foundation of China(Grant Nos.61825505,91536217,and 61127901).
文摘We demonstrate the transmission of a microwave frequency signal at 10 GHz over a 112-km urban fiber link based on a novel simple-architecture electronic phase compensation system.The key element of the system is the low noise frequency divider by 4 to differentiate the frequency of the forward signal from that of the backward one,thus suppressing the effect of Brillouin backscattering and parasitic reflection along the link.In terms of overlapping Allan deviation,the frequency transfer instability of 4.2×10-15 at 1-s integration time and 1.6×10-18 at one-day integration time was achieved.In addition,its sensitivity to the polarization mode dispersion in fiber is analyzed by comparing the results with and without laser polarization scrambling.Generally,with simplicity and robustness,the system can offer great potentials in constructing cascaded frequency transfer system and facilitate the building of fiber-based microwave transfer network.
文摘Based on uniform fiber Bragg grating bonded with a magnetostrictive rod in the non-uniform magnetic field,a novel PMD compensation technique is proposed.This all-fiber PMD compensation technology is cost-effective and flexible in designing the differential group delay profile.